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العلاقه بين الجهد التاكسدي والهرمونات الدهنيه للاطفال المصابين بالربو القصبي

Author name: افراح نزار طالب
Supervisor name: مفيد جليل عوض | سهير عيسى القيسي
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: الربو هو اكثر امراض الجهاز التنفسي السفلي المزمنة شيوعا في الطفولة في جميع انحاء العالم. الربو غالبا ما يبدا في وقت مبكر من الحياة ولها دورات متغيرة والنماذج الظاهرية غير المستقرة التي قد تقدم او تحويل مع مرور الوقت. قد ينجم عن الاطفال في سن ما قبل المدرسة عدد من الظروف المختلفة. حوالي نصف ازيز مرحلة ما قبل المدرسة تصبح غير متناظرة في سن المدرسة بغض النظر عن العلاج. ومع ذلك، قد تستمر اعراض الربو، في كثير من الاحيان للحياة، وخاصة في حالات التاتبي واكثر شدة. البدانة عامل خطر لتطور الربو. وقد ثبت جيدا ان السمنة تتميز ايضا بالتهابات نظامية منخفضة الدرجة تقلل من سلسلة من الوسطاء. اديبوكينس، التي تحفز على حالة تنشيط التهابات في اجهزة بعيدة الى الانسجة الدهنية. في لبتين السمنة واديبونيكتين، هما الهرمونات الرئيسية التي تشارك في التوازن الالتهابي والتي هي ذات الصلة المحتملة في الربو. هناك ادلة متزايدة على وجود علاقة ايجابية بين الربو والبدانة لدى الاطفال والبالغين. اديبوكينس تنظيم العديد من وظائف التمثيل الغذائي والالتهابات. وقد اظهرت العديد من الدراسات ان انواع الاكسجين التفاعلية(ROS) تلعب دوررائيسيا في بدء وكذلك تضخيم الالتهابات في الشعب الهوائية الربو. انتاج روس الزائد في الربو يؤدي الى تغيير في مضادات الاكسدة الانزيمية الغير انزيمية الرئيسية مثل الكاتالاز، الجلوتاثيون ومضادات الاكسدة الكلية. هذه الدراسة هي لتسليط الضوء على اختلال اكسدة ومضادات الاكسدة فيما يتعلق بمستوى اديبونيكتين في الاطفال المصابين بالربو. اديبونيكتين، اللبتين، الكاتالاز، الجلوتاثيون، ومضادات الاكسدة الكلية ومالونديالدهيد تم قياسها في 100 طفل. تم تسجيل 60 مريضا حديثا بالربو و40 طفلا غير مصابين بالربو مع العمر والجنس المقارنين في هذه الدراسة. الاطفال الربو تنقسم الى مجموعتين 30 مريضا في كل مجموعة (البدناء وغيرالبدناء ). تراوحت اعمار المرضى والسيطرة بين (2 سنة - 12 سنة). اديبونيكتين، اللبتين ومضادات الاكسدة الكلية التي تم تقديرها من قبل تقنية الانزيم المناعي اليزا ، الجلوتاثيون بواسطة هبلك، الكاتالاز ومالونديالدهيد بواسطة الطيف. اظهرت نتائج الدراسة الحالية زيادة في الليبتين وخفض مستويات الاديبونيكتين في المجموعة البدناء مما هو عليه في المجموعة التي لاتعاني السمنة لدى مرضى الربو والسيطرة بفارق معنوي (P <0.04) و(P <0.03) على التوالي. بالاضافة الى هذه الزيادة في مالونديالدهيد وانخفاض الكاتالاز، ومضادات الاكسدة الكلية ومستويات الجلوتاثيون، مع وجود فرق كبير 0.01)>p). لوحظ وجود ارتباط معنوي ايجابي بين اللبتين ومؤشر كتلة الجسم، ارتباط معنوي ايجابي بين الجلوتاثيون ومؤشر كتلة الجسم، ارتباط معنوي سلبي بين الاديبونيكتين مع الجلوتاثيون وارتباط معنوي ايجابي بين اجمالي مضادات الاكسدة والمالونديالدهيد. ونتائج الدراسة اعلاه كشفت عن وجود اختلال اكسدة ومضادات الاكسدة بين الاطفال المصابين بالربو يعانون من السمنة المفرطة، بالمقارنة مع التغيرات في مستوى اديبوكينس. بين الاطفال المصابين بالربو الذين يعانون من السمنة المفرطة وزيادة مستويات اللبتين والاديبونيكتين على التوالي حيث تشير الى ارتباط كبير بين اديبوكينس والسمنة في الاطفال الذين يعانون من الربو. زيادة القوى المؤكسدة وتقليل القدرة المضادة للاكسدة، معا نتائج تدعم بقوة ان الاكسدة هو زيادة في الاطفال الذين يعانون من الربو ويمكن ان تلعب دورا في التسبب في الربو. | Asthma is the most common chronic lower respiratory disease in childhood throughout the world. Asthma most often starts early in life and has variable courses and unstable phenotypes which may progress or remit over time. Wheeze in preschool age children may result from a number of different these conditions; around half of preschool wheeze become asymptomatic by school age irrespective of treatment. However, asthma symptoms may persist, often for life, especially in atopic and more severe cases. Obesity is a risk factor for the development of asthma. It has been well established that obesity is also characterized by low - grade systemic inflammation that reduces a series of mediators. Adipokines, which induce an inflammatory activated state in organs distant to adipose tissue. In obesity leptin and adiponectin, are the two main hormones involved in inflammatory balance and which are potentially relevant in asthma. There is an increasing evidence of a positive correlation between asthma and obesity in children and adults. Adipokines regulate several metabolic and inflammatory functions. Several studies have shown that reactive oxygen species (ROS) play a key role in initiation as well as amplification of inflammation in asthmatic airways. Excessive ROS production in asthma leads to alteration in key enzymatic as well as nonenzymatic antioxidants such as catalase, glutathione and total antioxidant . The aim of this study to assess of the leptin and adiponectin in sera of control and asthma groups and to study the correlation between adipokines (leptin and adponectin) and oxidative stress in asthmatic children. Adiponectin , leptin, catalase, glutathione , total antioxidant and malondialdehyde were measured in 100 children; 60 newly diagnosed with asthma and 40 non asthmatic children with the comparable age and sex were enrolled in this study . Asthmatics children subdivided in two groups 30 patients in each group( obese and nonobese). Ages of patients and control ranged between (2years - 12 years). Adiponectin , leptin and total antioxidant were estimated by enzyme - linked immunoassay ELISA technique, glutathione by HPLC, catalase and malondialdeheyde (MDA) by spectrophotometer. Results in present study are shown an increase in leptin and decrease adiponectin levels in the obese group than in non - obese group in asthmatic patients and control with significant difference (P<0.04) and (P<0.03) respectively. In addition to that increase in malondialdehyde and decrease catalase, total antioxidant and glutathione levels in asthmatic children than control, with significant (p<0.01) difference. There were significant (P>0.004) positive correlation observed between leptin and BMI , significant (P>0.03) positive correlation between glutathione and BMI, while significant (p<0.032) negative correlation between adiponectin with glutathione and significant (p<0.04) positive correlation between total antioxidant and malondialdehyde. The Present study concludes that Among obese asthmatics children there is an increase and decrease levels of leptin and adiponectin respectively that indicate the significant association between adipokines and obesity in those asthmatic children. Increase of oxidant forces and decrease antioxidant capacity, together results strongly support that oxidative stress is increased in asthmatic children and may play a role in the pathogenesis of asthma. The existence of an oxidant - antioxidant imbalance among obese asthmatics children, in parallel to changes in adepokines level

الكشف الجزيئي للفايروس البشري المتوجه للخلايا اللمفاوية التائيه - النوع الاول والتعبير البروتيني ل P27, CDK6,CDK4 وBcl - 2 في سرطان الغدد اللمفاوية الهودجكن واللاهودجكن == Molecular Detection of Human T Lymphotropic Virus Type - 1 (HTLV - 1) and Expressional Proteins of CDK4, CDK6, P27 and Bcl - 2 in Hodgkin?s and Non - Hodgkin?s Lymphomas

Author name: نور سامي عبود الليباوي
Supervisor name: جواد كاظم طراد الخفاجي | شاكر حماد محمد العلواني
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: صممت هذه الدراسة على انها دراسة بحثية ذات اثر رجعي ,وسيطره . اذ اشتملت على120خزعة نسجية من منطقة الغدد اللمفاوية المحفوظة بالفورمالين والمطمورة بشمع البارافين.جمعت هذه النماذج من ارشيفات الانسجة المرضية لمختبرات مستشفى الحلة التعليمي/ محافظة بابل , مستشفى الحسين التعليمي/ محافظة كربلاء ,مستشفى الصدر التعليمي/ محافظة النجف ,مستشفى الحسين التعليمي/ محافظة المثنى ومستشفى القادسية التعليمي/ محافظة القادسية وكذلك العديد من مختبرات الانسجة المرضية الخاصة الموجودة في بابل ,بغداد, كربلاء, القادسيه, المثنى اذ جمعت هذه العينات للفترة من اذار 2016 الى كانون الاول 2016. هذه النماذج تعود للمرضى المصابين بسرطان العقد اللمفاوية للسنوات من 2011 لغاية 2016 .قسمت هذه العينات حسب المجموعات التالية : - 1 - اربعون قطعة نسيجية لمفاوية مصابة بسرطان العقد اللمفاوية نوع هودجكن .2 - اربعون قطعة نسيجية لمفاوية مصابة بسرطان العقد اللمفاوية نوع اللاهودجكن .3 - اربعون قطعة نسجية لعقد لمفاوية (لايظهر عليها اي تغيرات مرضية نسيجية) ظاهريا سليمة استعملت كمجموعة سيطرة .بعد التقطيع النسيجي لخزع العقد اللمفاوبة وتصبيغها باستخدام صبغتي الايوسين والهيماتوكسلين تم اجراء الفحص التاكيدي الدقيق لغرض التشخيص النهائي من قبل اخصائي الامراض النسيجية لهذه الدراسة. تم تصميم الجانب العملي لهذه الدراسة الذي اتخذ مسارين رئيسين : - 1. التحديد الجزيئي للفايروس البشري المتوجه للخلايا اللمفاوية التائيه من النوع الاول بفحصها داخل خلايا الانسجة اللمفاوية حيث تم انجازه بوساطة استخدام تقنية التهجين الموضعي ذات الحساسية العالية .2. اجراء دراسة كيميائية - نسيجية مناعية لوصف الحالة التعبيرية ل CDK4 وCDK6 ومثبط CDK (p27) وفحص الجينات السرطانية للخلايا اللمفاوية B (Bcl - 2 ) في الانسجة المصابة بالهودجكن واللاهودجكن والعقد اللمفاوية السليمة ظاهريا (غير مصابة).ان مجمل النتائج التي تم الحصول عليها هذه الدراسة كانت كما يلي : 1 - نسبة الذكور( (57.5% المصابين بسرطان الغدد اللمفاوية الهودجكن واللاهودجكن ومجموعة السيطرة كانت اعلى من نسبة الاناث (42.5%) في هذه المجاميع الثلاثة. حيث كانت نسبة الذكور/اناث هي1 : 1.35.2 - اظهر الفحص النسيجي ان النسبة العليا من مرضى الهودجكن كان من الدرجة المنخفضة (42.5%) يتبعها الدرجة المتوسطة (35%) وادنى نسبة هي الدرجة العليا (22.5%). بينما النسبة العليا من مرضى اللاهودجكن كانت من الدرجة المنخفضة والمتوسطة %37.5)) وادنى نسبة هي الدرجة العليا ( 25%).ا - نتائج الفايروس البشري المتوجه للخلايا اللمفاوية التائيه من النوع الاول وCDK4 وCDK6 ومثبط CDK (p27 ) وكذلك الجينات السرطانية للخلايا المفاوية B (Bcl - 2 ) في الانسجة المصابة بالهودجكن : 1 - النتائج الموجبة لجين HBZ للفايروس البشري المتوجه للخلايا اللمفاوية التائيه من النوع الاول بتفاعل التهجين الموضعي كانت ( 22.5%) 2 - اظهرالاختبارالكيميائي النسجي المناعي لـ p27 ان 35% من الانسجة كانت موجبة .3 - اظهرالاختبارالكيميائي النسجي المناعي لـ CDK4 ان 35% من الانسجة كانت موجبة .4 - اظهرالاختبارالكيميائي النسجي المناعي لـ CDK6 ان 57.5 % من الانسجة كانت موجبة . 5 - اظهرالاختبارالكيميائي النسجي المناعي لـ Bcl - 2ان47.5 % من الانسجة كانت موجبة .6 - تم تمييز علاقة طردية قوية تربط بين تحديد والانتشارالتعبيرالبروتيني والكثافة للفيروس وCDK4 .7 - وجدت علاقة طردية قوية بين تحديد والانتشارالتعبيرالبروتيني والكثافة للCDK4 وCDK6 .وايضا وجدت علاقة بين تحديد وكثافة ال CDK6 وBcl - 2.8 - تم تمييز علاقة طردية قوية تربط بين تحديد والانتشارالتعبيرالبروتيني والكثافة ل p27 وعمر المرضى. كذلك علاقة طردية بين p27 وBcl - 2.ب‌ - نتائج للفايروس البشري المتوجه للخلايا اللمفاوية التائية من النوع الاول وCDK4 وCDK6 ومثبط CDK (p27 ) وكذلك الجينات السرطانية للخلايا المفاوية B (Bcl - 2 ) في الانسجة المصابة باللاهودجكن : 1 - النتائج الموجبة لجين HBZ للفايروس البشري المتوجه للخلايا اللمفاوية التائيه من النوع الاول بتفاعل التهجين الموضعي كانت (45%) بينما لم تظهر اي حالة موجبة بتفاعل التهجين الموضعي للفايروس ضمن مجموعة السيطرة .2 - اظهرالاختبارالكيميائي النسجي المناعي لـ p27 ان 42.5% من الانسجة كانت موجبة. بينما لم تظهر اي حالة موجبة للp27 بواسطة الاختبارالكيميائي النسجي المناعي ضمن مجموعة السيطرة.3 - اظهرالاختبارالكيميائي النسجي المناعي لـCDK4 ان 50% من الانسجة كانت موجبة. بينما لم تظهر اي حالة موجبة في هذا الاختبار في مجموعة السيطرة.4 - اظهرالاختبارالكيميائي النسجي المناعي لـ CDK6 ان 72.5% من الانسجة كانت موجبة . بينما لم تظهر اي حالة موجبة في هذا الاختبار في مجموعة السيطرة.5 - اظهرالاختبارالكيميائي النسجي المناعي ل Bcl - 2 ان 72.5% من الانسجة كانت موجبة. بينما لم تظهر اي حالة موجبة في هذا الاختبار في مجموعة السطرة.6 - تم تمييز علاقة طردية قوية تربط بين تحديد الفيروس وBcl - 2 وكذلك وجدت علاقة قوية طردية تربط بين الانتشارالتعبيرالبروتيني والكثافة للفايروس وCDK6.7 - وجدت علاقة طردية قوية بين تحديد والانتشارالتعبيرالبروتيني والكثافة للBcl - 2 وCDK6 .وايضا وجدت علاقة بين تحديد وكثافة ال p27 وBcl - 2 فقط .كذلك وجدت علاقة عكسية بين عمر المريض وBcl - 2 .8 - تم تمييز علاقة طردية تربط بين كثافة CDK4 وp27 وكذلك بين CDK4 وBcl - 2

دراسة بكتيرية ووراثية لبكتريا Gardnerella vaginalis وعلاقتها بالولادة المبكرة == Bacteriological and Molecular study of Gardnerella vaginalis association with preterm labor

Author name: ازل علاء عباس الربيعي
Supervisor name: الهام عباس بنيان الساعدي | لميس عبد الرزاق عبد اللطيف
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: In this study , one hundred fifty samples were collected from paitents with preterm labor (PTL), who have been attending to Babylon Maternity and pediatric hospital and Al - Hilla Teaching Hospital, at the period from February to October 2016. Two swabs were collected one for culturing and the other for direct extraction for isolation Gardnerella vaginalis.Out of the 150 samples only 6(4%) on culture and 30 (20%) on molecular level isolated from preterm labor caused by Bacterial vaginosis , Urinary tract infection and aborted women. The results isolation and laboratory diagnosis as well as biochemical test approved that there is only 6 isolates belong to G.vaginalis confirmed by using Vitek 2 system and molecular detection by specific primers.Preterm birth is one of the most common causes of neonatal morbidity and mortality. Associated with sub sequent preterm labor in up to 40% of cases as shown in our resultsThe isolates are varied in their ability to produce sidrophore and extracellular protease in addition to their hemolytic activity .Adherence activity were investigated and indicate that G.vaginals have pili on her surface help her to attached and initiated infection Metronidazole was effective in prevent adherence at low concentration (5%) was 100% percentage.All isolates are able to produce biofilm in different level which provided as main step in pathogenesis caused it can evade and evoke the action of immune response and antibiotics , Alum , sodium chloride and sodium bicarbonate were shown very high effectively to eradicationSummaryIIG.vaginalis biofilm which gave results (0%) whereas the thymol extract (carvacrol) were moderate in action gave (50%) effect on Biofilm .Results also preveld that increased of pH value give a chance to overgrowth of G.vaginalis .The results indicated that Lactic acid considered as a limiting factors preventing growth of G.vaginalis when its grown with lactic acid , measured by optical Density (OD) the high production level is (1.901) in 2% concentration Whereas the lowest level is (0.32) in 10% concentration.Isolates Have ability to produce wide spectrum Bacteriocin which inhibited growth of both Gram positive and Gram negative bacteria that founded in vagina environment, Staphylococcus saprophyticus were the most bacteria that inhibited .extracted Vaginolysin was have a completed hemolytic activity in different temperatures (37 - 38 - 40 - 42). The results showed that its activity as were increased in high temperature.Recent study were clarified that purified vaginolysin was active in presence of cholesterol in media, gave (1.205) growth rate measured by the optical density at (100%) concentration. vaginolysin is cholesterol - dependent cytolysin (CDCs) toxin.Antimicrobial activity were investigated to the extracted Vaginolysin to evaluation of its activity depending on inhibition zone, the results showed that candida is more affective between the other microorganism gave (1.3)mm.Some virulence factor have been detected in molecular level ( Vly - SI - LuxS - LexA - rec a - Pl - Fur - Omp - Gal - protease ). Which wereSummaryIIIvaried in production may be as a results to the un presence of this gene in bacteria , may be silent gene or due to the amount of bacteria in sample are rare.Three Antibiotics were used at a molecular level (Tet b) were varied between resistance and sensitive to this gene (10) sample are resist,(RdxA) all sample are sensitive to its gene at percentage (100%), whereas (erna)gene were resist in all samples (100%).The results show there was no sequence homology between Mycoplasma spp. and G. vaginalis in the adhesion level this were detected by P30/P32 specific primer .The outcome of RFLPS - PCR is confirmed that G.vaginalis is virulent and have a role in preterm labor by degradation of membranes with the association of variable Silidase and presence of β - Galactosidase .MBL (mannose binding lectin ) levels were have a direct role pregnancy. It is also apparent that MBL plays a role in the defense against vaginal infection. MBL is essential to successful pregnancy in regards to maternal defense against infection, recent study indicate that MBL deficiency related to pregnancy outcome disorderedthis considered the first study of mannose in Iraq .DNA sequencing were done for two main virulence factor Phospholipase gene and Quorum sensing gene which showed some variation , then recorded in NCBI - gene sequencing as first descriped in Iraq.

التاثير المايكروبي المضاد لدقائق الفضة النانوية ضد بكتريا الزوائف الزنجارية المعزولة من عينات سريرية == The Antimicrobial Effect of Silver Nano Particles (AgNPs) Against Pseudomonas aeruginosa Isolated from Clinical Samples

Author name: سارة عقيل حسن التميمي
Supervisor name: هدى هادي الحسناوي
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: اجريت هذه الدراسة للكشف عن التاثيرالمايكروبي المضاد لدقائق الفضة النانوية ضد بكتريا الزوائف الزنجارية المعزولة من عينات سريرية, تم جمع 100 عينة من مصادر سريرية مختلفة, تضمنت العينات السريرية عينات الحروق , والادرار, والدم, واصابات الاذن, والقشع تم اخذ هذه العينات من المرضى الراقدين في مستشفى الحلة التعليمي خلال الفترة من تشرين الثاني 2016 الى كانون الثاني 2017. زرعت جميع العينات على وسط السترمايد, وسط اكار الدم, وحضنت كل الاطباق هوائيا بدرجة حرارة C°37 لمدة 18ساعة. تم تشخيص بكتريا الزوائف الزنجارية بالاعتماد على الصفات المظهرية والكيموحيوية.كان توزيع العزلات كالاتي : 22(52.4%) من عينات الحروق, 8(19%) من عينات الادرار, 14.3)6%) عينة من المرضى المصابين بالالتهاب الاذن الخارجية, 4(9.5%) من عينات الدم,2(4.7%) من عينات القشع. اظهرت نتائج اختبار الحساسية باستخدام طريقة الانتشار في الوسط ان جميع العزلات(26) كانت مقاومة لكل من الببراسلين (100%), السيفوتاكسيم (100%),بينما نسبة المقاومة لكل من الاميكاسين (88%), سيفترياكسون (65%), جنتامايسن (62%), بينما وجدت نسبة مقاومة قليلة للسفتازديم (15%), وكل العزلات كانت حساسة (100) لكل من الميروبينيم, اوفلوكساسين, نورفلوكساسين والسبروفلوكساسين. تم في هذه الدراسة ايضا الكشف عن تكوين الاغشية الحيوية بواسطة طريقتين : طريقة الطبق الزرعي النسيجي (TCP) وطريقة صبغة الكونكو الحمراء (CRA) فكانت النتائج كالاتي : وجد ان في طريقة الطبق الزرعي النسيجي كانت جميع عزلات الزوائف الزنجارية والبالغ عددها (9) منتجة للاغشية الحيوية, (4) من اصل (9) (44%) من عزلات الزوائف الزنجارية انتجت مستعمرات سوداء بواسطة طريقة صبغة الكونكو الحمراء. وكذالك في هذه الدراسة تم الكشف عن تاثير جزيئات الفضة النانوية ((AgNPs على تكوين الاغشية الحيوية باستخدام تراكيز مختلفة (µg/ml 2.5, µg/ml 5, 10 µg/ml, 20µg/ml),حيث اظهرت النتائج ان اعلى فعالية لجزيئات الفضة النانوية كانت عند التركيز (20) وبنسبة تثبيط (100%), من جهة اخرى تم اختبار التاثير البكتيري المضاد لجزيئات الفضة النانوية ضد مختلف انواع العزلات البكتيرية باستخدام طريق التخافيف في الوسط الصلب وتراكيز مختلفة من جزيئات الفضة النانوية (12.5 µg/ml, 25 µg/ml, 50 µg/ml, (100 µg/ml, 200 µg/ml وكانت العزلات كالتالي : ـ(S. aureus, E. coli, E. cloacae, K. pneumonia, P. aeuroginosa)اظهرت النتائج ان اعلى فعالية لجزيئات الفضة النانوية كانت عند التراكيز(100 µg/ml, 200 µg/ml).ايضا تم تعريض ظاهرة السوارمنك في عزلات الزوائف الزنجارية لتراكيز مختلفة من جزيئات الفضة النانوية (2.5 µg/ml, 5 µg/ml, 10 µg/ml ), ووجد ان اعلى نشاط لجزيئات الفضة النانوية ضد ضاهرة السوارمنك وانتاج البايوسيانين كانت بتركيز ((10 µg/ml, 5 µg/ml .تم زراعة جميع عزلات بكتريا الزوائف الزنجارية (26)عزلة بوجود نترات الفضة (AgNO3) بتراكيز تتراوح (100 µg/ml - 400 µg/ml ) باستخدام طريقة التخافيف في الوسط الصلب مع قدرات مختلفة لانتاج البيوسيانين. اظهرت النتائج ان جميع العزلات 26((100 المنتجة للبايوسيانين كانت مقاومة للسلفر نايتريت (AgNO3) من خلال ظهور نمو في الطبق الحاوي على التراكيز المذكورة نترات الفضة (AgNO3).في هذه الدراسة تم اختبار بكتريا الزوائف الزنجارية لانتاج البكتريوسين باستخدام عزلات بكترية مختلفة تضمنت العزلات (امعائية مذرقية,مكورات العنقودية الذهبية,اشريكية قولونية, كلبسيلة رئوية). كذلك تم العثور على مجموعة واسعة من منطقة تثبيط (24mm - 30mm) في الانواع البكتيرية اعلاه مع قطر (30mm, 28mm, 24mm, 30mm) على التوالي. عزلات (امعائية مذرقية, كلبسيلة رئوية) كانت الاكثر تاثر والتي انتجت قطر تثبيط ((30mm. في هذه الدراسة ايضا تم تقييم علاقة مقاومة الفضة مع انتاج بيوسيانين في بكتريا الزوائف الزنجارية متعددة المقاومة للمضادات الحيوية. في هذه الدراسة تم استخدام تقنية تفاعل البلمرة المتسلسل للتاكد من وجود بعض الجينات. في هذه التقنية، تم فحص جينات bla - IMP)) التي تشفر الى انزيم ميتالو - β - لاكتاميز المسؤول عن مقاومة ايميبينيم وجينات (silS ,silE) التي تشفر لمقاومة الفضة في عزلات بكتريا الزوائف الزنجارية بواسطة استخدام برايمرت خاصة. وقد وجد ان جميع العزلات ال 26 (100%) من بكتريا الزوائف الزنجارية كانت سلبية لهذه الجينات. كما تم استخدام اثنين من البرايمرات المحددة للكشف عن فينازين (بيوسيانين) (phzS, phzM). اظهرت النتائج لل (phzM) ان من اصل 26)) عزلة , 21 (80.8%) اعطت نتيجة ايجابية, , فيما يخص (phzS gene) وجد ان 14(% 53.9) عزلة كانت حامله لهذا الجين . والخاتمة ان جزيئات الفضة النانوية (AgNps) تمتلك تاثير ضد الاغشية الحيوية وايضا لها تاثير بكتيري مضاد ضد بكتريا الزوائف الزنجارية وانواع بكتيرية اخرى, والتي من الممكن استخدامها كعلاج بديل. فيما يخص انتاج البايوسيانين ومقاومة الفضة، ظاهريا كان هناك تاثير البايوسيانين على مقاومة الفضة ولم تكن مقاومة الفضة بسبب نقل وجود جينات (silS, silE). | This study was conducted to detect the antimicrobial effect of silver nanoparticles (AgNPs) against Pseudomonas aeruginosa isolated from clinical samples, total of 100 specimens were collected from different clinical sites included urine, burns, ear, blood , and sputum. The specimens were taken from patients admitted to Al - Hilla Teaching Hospital during a period extended from November 2016 to January 2017. All specimens were cultured on selective medium (cetrimide agar), blood agar, then incubated at 37°C for 18 hr. The isolated of P. aeurginosa were diagnosed depending on morphological and biochemical characteristics.The distribution of P. aeurginosa isolates was as follows : 22(52.4%) isolates from burns, 8(19%) isolates from urine, 6(14.3%) isolates from patients with otitis externa, 4(9.5%) isolates were isolated from blood and 2(4.7%) isolates from sputum. Antibiotic susceptibility test using disc diffusion test revealed that all isolates (26) were resistant (100%) to Piperacillin, Cefotaxime. While the resistance rate for Amikacin (88%), Ceftriaxone (65%), Gentamicin (62%), but low resistance rate was found to Ceftazidime (15%) and all isolates were sensitive (100%) to Meropenem, Ofloxacin, Norfloxacin and Ciprofloxacin. The biofilm formation in P. aeurginosa isolates was investigated by two methods include, tissue culture plates method (TCP) and congo red agar method (CRA). The results showed that all isolates 9 (100%) were found to be biofilm producer when investigated by TCP assay, and 4 out of 9 (44. %) isolates of P. aeurginosa were producing black colonies when detected by CRA method.The effect of AgNps on biofilm formation was tested by using different concentrations of silver nanoparticles (2.5 μg/ml, 5 μg/ml,10 μg/ml, 20μg/ml). The results showed that the highest activity was at a concentration of 20 μg/ml, with an inhibition rate of 100%. On the other hand the antibacterial activity of AgNps was tested against different bacterial species isolates (Staphylococcus aureus, Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, Pseudomnas aeurginosa) using agar dilution method with different concentrations of silver nanoparticles (12.5 μg/ml, 25 μg/ml, 50 μg/ml, 100 μg/ml, 200 μg/ml). The results showed that the highest activity was at a concentration of (100 μg/ml and 200μg/ml). On the other hand Swarming motility in P. aeruginosa isolates was detected and subjected to different concentrations of (AgNps) (2.5 µg/ml, 5 µg/ml, 10 µg/ml), it was found that the highest activity of AgNps against swarming motility and pyocyanin production of P. aeurginosa was at a concentration of (5 µg/ml, and 10μg/ml).The relation of silver resistance with pyocyanin production in P. aeruginosa was assessed. Screening test for silver resistance was performed by agar dilution method, all (26 isolates) of P. aeruginosa were cultivated in the presence of AgNo3 at a concentration (100 µg/ml - 200 µg/ml, 400µg/ml) using agar dilution method with differing capacities for pyocyanin production. All isolates of P. aeurginosa 26(100%) that produce pyocyanin were found to be resistant to AgNo3.In this study P. aeruginosa isolates were tested for bacteriocin activity by the agar well diffusion method using different bacterial isolates : E. coli, K. pneumoniae, S. aureus, E. cloacae. Wide range of inhibition zone (24mm - 30mm) was found against above bacterial species with diameter (28mm, 30mm, 24mm, 30mm), respectively. The most affected bacteria were K. pneumoniae and E. cloacae isolates, which produce inhibition zone (30)mm.PCR technique was used in this study for investigation some genes. In this technique, blaIMP gene that encode Metallo - β - lactamase enzyme responsible for imipenem resistance and (silE and silS) genes that encoding silver resistance were investigated in P. aeuroginosa isolates by using specific primers. It was found that all 26 (100%) isolates of P. aeuroginosa were negative for these genes. Also two specific primers were used to detect phenazine (pyocyanin) modifying genes (phzM, phzS). According to phzM gene, it was found that out of 26 P. aeuroginosa isolates, 21 (80.8%) isolates gave positive results at 330 bp, in regard to phzS gene, it was found out of 26 P. aeurginosa isolates, 14 (53.9%) isolates gave positive result at 664 bp.In conclusion AgNps have an antibiofilm, antibacterial activity against P. aeruginosa and different bacterial species that could be used as an alternative therapy. In regard to pyocyanin production and silver resistance, phenotypically there was effect of pyocyanin pigment on silver resistance and the silver resistance was not due to carriage of silE, silS genes.

التشخيص والتوصيف الجزيئي لبكتريا Clostridium perfringens المعزوله من حالات مرضية سريرية في مدينة الحلة == Molecular Diagnosis and Characterization of Clostridium Perfringens from Clinical Samples in Al - Hilla city

Author name: علياء محمد حمود الشمري
Supervisor name: علاء هاني الجراخ | ميساء صالح الشكري
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: تهدف هذه الدراسة لمعرفة وبائية بكترياC. Perfringens في العينات المؤخوذة في محافظة بابل. تم جمع 140عينة من الجروح العميقة من المرضى الداخلين في مستشفيات مدينة الحلة الرئيسية (مستشفى الحله التعليمي ومدينة مرجان الطبيه) والذين يعانون من مرض السكري المزمن وايضا من مرضى تعرضوا الى طلق ناري فضلا عن المرضى الذين يعانون من التهاب الخلوي اللاهوائي في الجلد(anaerobic cellulitis ) للفترة من شهر شباط ولغاية شهرتشرين الاول 2016. بالاضافه الى ذلك تم تشخيص وعزل بكترياC. perfringens بطرق مختلفة منها استخدام الطرق البكتيرية التقليدية من خلال طرق التنمية على الاوساط الزرعية الاختيارية لهذه البكتريا واظهرت النتائج الحصول على 3 (2.14%)عزلات كان عزل اثنان منها 1.42%)) من مرضى السكري المزمن اما العزله الثالثه (0.72%) فقد تم الحصول عليها من الذين تعرضوا لطلق ناري في حين لم يتم الحصول على عزلات من المرضى الذين يعانون من الالتهاب الخلوي اللاهوائي . وكذلك تم تاكيد التشخيص باستخدام المعلم الوراثي المستند على دور جين 16s rRNA وجين16S - 23S spacer rRNA حيث اظهرت النتائج, من اصل 140 عزلة فان 7 عزلات تعود لبكتريا C. perfringens. بالاضافة الى ذلك, تم التحري عن قابلية هذه البكتريا واختبار قابليتها على انتاج انزيم (phpspholipase C) ووجد ان جميع العزلات منتجة الى هذا الانزيم. كما تم الكشف عن حساسية عزلات البكتريا اللاهوائية تجاه 24 مضادا حيويا. بينت نتائج الدراسة ان جميع العزلات اظهرت حساسية عالية (100%) تجاه كل من penicillins .مثل benzypencillin, ,amoxicillin فضلا عن حساسيتها تجاه  - lactamase inhibitor مثل Ampicillin - sulbactam وحساسيه عالية لكل من metronidazole وaminoglycosidesومن ناحية اخرى، اظهرت جميع العزلات مقاومة عالية لكل من مضادات tetracyclin, Linezolid, levofloxacin, erthromycin بينما اظهرت هذه العزلات تغاير في درجات المقاومة تجاه مضادات pipracillin, Clindamycin, and Impenem.تم استخدام الطرق الوراثية في الكشف عن جينات المقاومة للمضادات الحياتية كجيناتM,Q,W,B) ) tet الخاصة بالكشف عن المقاومة للتتراسايكلين وجينات erm(A,B) للكشف عن المقاومة للكلندامايسين وجين nim للكشف عن المقاومة للمترونيدازول حيث اظهرت النتائج ان الجين tet M كان ذا سيادة عالية بنسبة 71.42 %تم استخدام طريقة التشخيص الجزيئي لتوكسينات البكتريا (alpha,epsilon, iota) للاستدلال على وجود جينات (cpa, etx, iap)، في C. perfringens وبنسبة 100%, 28.4%, 28.4% )) على التوالي.بالاضافة الى ذلك تم استخدام جينات cpa, etx and iap لقياس تعاقب القواعد النيتروجينية للمادة الوراثية للعزلات المدروسة فضلا عن تسجيلها في بنك الجينات العالمي ( ,(Gene Bank,اذ تم خلال هذه الدراسة ولاول مرة في العراق، الحصول على خمسة ارقام انضمام الى بنك الجينات العالمي (5 accession numbers)، حيث تم نشر هذه الارقام في بنك الجينات الامريكي gene bank - NCBI وهذه الارقام هي : جينiap : KY523199, KY523200 اما فيما يخص الجينetx فكانت الارقام هي : KY523201, KY523202 وفيما يخص الجين cpaفكان رقم الانضمام هو : . KY523203تعد هذه الدراسه انها اول دراسه في العراق تضمنت تحليل , دراسه تعاقب القواعد النايتروجينية للمادة الوراثية فضلا عن التسجيل في بنك الجينات العالمي لسموم عزلات محلية من بكتريا C.perfringens معزولة من عينات سريرية. | This cross sectional and hospital - based study aimed to studying the incidenceof Clostridium perfringens in clinical samples in Babylon province. A total of 140 wound swabs were taken from patients admitted to two main hospitals in Hilla city, Iraq (Hilla Teaching Hospital and Medical Marjan City), during the period from February to October 2016. Swabs were collected from diabetic patients, anaerobic cellulitis, and bullet wounds. These wound swab samples were subjected to different methods for identification of C. perfringens according to standard method. It was found that 3 (2.14%) C. perfringens isolates were recovered, of which 2 isolates (1.42%) were obtained from diabetic patients, 1 isolates (0.72 %) from bullet wounds, No isolates are recovered from the other clinical samples (cellulitis). Furthermore, molecular detection method was applied by using 16s rRNA, 16S - 23S intergenic spacer rRNA genes as a genetic marker for confirmation of detection of C. perfringens isolates,7 isolates of C. perfringens out of 140 are detected by using PCR with specific primer.The study also focuses on the ability of this bacteria to produce Phospholipase C and it was found that all isolates are positive for this enzyme (100%) . The results of antibiotic susceptibility testing using Vitek 2 system and disc diffusion method (DDT) of C. perfringens isolates (No.= 3) against 24 antibiotics showed that all isolates were highly sensitive to penicillins, (benzylpenicillin, and amoxicillin), all isolates (3/3) were sensitive to  - lactamase inhibitor such as Ampicillin - sulbactum. They were more susceptible to metronidazole and aminoglycosides in (3/3). On the other hand, all isolates were highly resistant to tetracycline, Linezolid ,levofloxacin, and erythromycin However, these isolates expressed different degree of susceptibility towards other antibiotics (Clindamycin, piperacillin and Imipenem). Molecular detection of C. perfringens of antibiotic resistance genes had been investigated and it had been found that tetracycline resistance gene tet M is the most commonly observed (71.42%) among ribosomal protection genes among C. perfringens isolates. While all isolates (7) gave negative results for other tetracycline resistance genes (tet W and Q, tet B, erm(A), erm(B),nim gens).Furthermore, detection of clostridial toxin (alpha, epsilon, iota toxins was applied using specific genes (cpa, etx, iap) and the results showed that the rate of the presence of these genes are : 100%, 28.8% and 28.4% respectively. The following genes : cpa, etx and iap were used for sequencing analysis, registration in gene bank - NCBI. Five accession numbers were obtained from registration of five sequences of these three genes at gene bank - NCBI : iap gene; accession numbers are : KY523199, KY523200etx gene; accession numbers are : KY523201, KY523202cpa gene; accession number is : KY523203. This is the first study in Iraq which employed analysis sequencing and registration in gene bank - NCBI, of clostriaial toxin of local isolates of C. perfringens obtained from clinical samples

تقييم دور بروتين عامل نمو بطانة الاوعية الدموية ونسبة الصوديوم, البوتاسيوم, والكالسيوم الى الكرياتينين في الادرار كفحص تشخيصي لمرضى ما قبل تسمم الحمل == The Role of Vascular Endothelial Growth Factor and Urinary Sodium, Potassium, and Calcium to Creatinine Ratio as Diagnostic Tests in Pre - eclampsia

Author name: غيث كامل جواد
Supervisor name: حيدر هاشم الشلاه | ملال محمد الجبوري
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: Preeclampsia is defined as hypertension associated with proteinuria arising de novo after the 20th week of gestation in a previously normotensive woman and resolving completely by the 6th postpartum week.It is a major cause of morbidity and mortality during pregnancy. There are many ways to diagnose the disease, based on clinical diagnosis and conduct some tests; screening tests measurement of the amount of protein found in the urine sample that had been collected for a period of twenty - four hours. In the present study, the ratio of (Na+, K+, and Ca++) to creatinine in the urine spot sample, in addition to the protein vascular endothelial growth factor in the serum were measured as an attempt to be used as screening or diagnostic tests for patients with pre - eclampsia. This study was carried out at Babylon Teaching Hospital for Gynecology and Pediatrics, in Babylon Province, Hilla City during the period between February 2016 till August 2016. This study included 88 women, 44 were patients diagnosed with preeclampsia in the second and third trimester and the other 44 were healthy pregnant women in the same period of pregnancy taken as a control. Cases with age over 135 year, BMI > 300, previous historyd of pre - eclampsia, family history of pre - eclampsia, multipled pregnancy and hydrops fetalis, pre - existing hypertension or renal disease, pre - existing vascular disease, and antiphospholipid syndrome were excluded. Serum levels of vascular endothelial growth factor were measured by using ELISA technique, while urine were collected to estimate calcium and creatinine by spectrophotometric method. Sodium and potassium by ion selective electrode technique. The ratio of sodium to creatinine, potassium to creatinine, and calcium to creatinine were calculated.Serum vascular endothelial growth factor level was significantly lower in patients with preeclampsia compared to control group (P value < 0.01).The sensitivity of VEGF to detect preeclampsia was (75%) while, it's specificity was (90.9%).Similarly, the urinary Na+/creatinine ratio and Ca++/ creatinine ratio was significantly lower in patients with pre - eclampsia compared to control groups (P value < 0.01). The sensitivity of urinary Na+/Creatinine ratio was (93%) and it's specificity was (70%). While the sensitivity of urinary Ca++/ creatinine ratio was (34%) and specificity was (97%).On the other hand, urinary K+/creatinine ratio was significantly higher in patients with pre - eclampsia compared to control groups (P value < 0.01).The sensitivity of urinary K+/creatinine ratio to detect pre - eclampsia was (77%) while, its specificity was (68%).This study concluded that urinary Na+/creatinine ratio can be used as a screening tests because of excellent sensitivity, however because of excellent specificity of vascular endothelial growth factor and urinary Ca++/creatinine ratio (90.9% and 97% respectively), they are convienent for diagnostic purpose.

علاقة هورمونات الغرلين, اللبتين, غلوكاغون والانسولين بمقاومة الانسولين بمرضى السمنة والناس الغير مصابين بالسمنة == Relationship between Ghrelin, Leptin, Glucagon and Insulin with Insulin Resistance in Obese Patients and Non - Obese Individuals

Author name: دعاء مهدي عمران
Supervisor name: علي حسين البياتي | سعد مرزة الاعرجي
General topic: Medicine
Specific topic: Physiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: تعتبرالسمنة وباءا عالميا حيث انها تؤثرفي حوالي اكثر من 2 مليار شخص حول العالم حتى عام2013, ان ارتفاع نسبة انتشار السمنة في كل من البلدان المتقدمة والنامية كانت نتيجة لعدد من الاسباب والتي تتمثل بالبيئة، الوراثة الطبية مثل اضطراب الغدد الصماء، والعلاج مثل العقاقير المضادة للذهان والمنشطات الستيرويدية, ان اغلب الناس البدينين يكونون عرضة للاخطار الكبيرة حيث تعرضهم للمضاعفات كداء السكري وارتفاع ضغط الدم وتصلب الشرايين، ومشاكل المفاصل، وامراض السرطان وخاصة السرطانات المحفزة بالهرمون، بالاضافة الى مشاكل في الجهاز التنفسي وغيرها من المضاعفات الاخرى, ان الهدف من هذه الدراسة هو اظهار تاثير زيادة الوزن على تمثيل تاهورمونات التالية : الغرلين, اللبتين, الانسولين والغلوكاكون في المرضى المصابين بالسمنة مع او بدون مقاومة الانسولين ومقارنتهم بالناس الغير مصابين بالسمنة مع او بدون مقاومة الانسولين, تم اخذ 100 شخصا منهم 50 شخصا مصابين بالسمنة و50 شخصا غير مصابين للفترة بين شهر كانون الثاني 2015 وشهر حزيران 2016 بمعدل اعمار بلغ (34.00±9.43) بالنسبة لمرضى السمنة و(34.50±7.40) بالنسبة للاشخاص الغير مصابين بالسمنة, تم الاعتماد على معامل كتلة الجسم لتفريق المجموعتين وتم سؤال الجميع حول ان كانوا مصابين بامراض معينة او يتناولون ادوية معينة تؤثر في وزنهم, وتم مختبريا اجراء الفحوصات التالية : فحص نسبة السكر في الدم, هورمون الانسولين, هورمون الغلوكاكون, هورمون اللبتين, هورمون الغرلين وتم قياس مقاومة الانسولين حسب المعادلة بين الانسولين والسكرو اظهرت النتائج وجود فرق معنوي بين المجموعتين (p value ≤ 0.05) فيما يخص اختلاف الجنس والتعليم وكذلك اختلافا معنويا (p value ≤ 0.05) فيما يخص الفحوصات المختبرية لنسبة السكر في الدم, نسبة هورمون الانسولين, هورمون اللبتين ومقاومة الانسولين فيما لم تظهر فرقا فيما يخص هورموني الغرلين والكلوكاكون.اعتمد الباحث في تعريب المصطلحات العلمية على : المعجم الطبي الموحد - انكليزي - عربي. رئيس التحرير د. محمود الجليلي - الطبعة الرابعه 2009 م , مطبعة المجمع العلمي العراقي. | Obesity is representing a global epidemic that affecting more than 2 billion peoples around the world on 2013. The obesity prevalence has risen in both developed and developing countries. Many causes have been implicated for developing obesity such as : environmental, hereditary, medical disease like endocrine disorders furthermore, some medication like antipsychotic drugs and steroids. Obese people are at high risk to develop much complication such as diabetes, hypertension, atherosclerosis, joints problems, cancers especially hormone dependent, respiratory problems and others. The aim of this study was to compare the impact of increase in weight on the clinical presentation of Ghrelin, Leptin, Insulin, and Glucagon in obese patients with or without Insulin resistance and compare it to that of non - obese individuals with or without Insulin resistance, one hundred people are included in this study attending Marjan medical city from December 2015 till June 2016, a fifty normal non - obese and fifty obese, the overall mean age of patients and controls were (34.00±9.43) and (34.50±7.40) years old, respectively, they are classified according to body mass index after measuring their weight, height, the mean BMI of case patients was (39.23±6.71 kg/m²) and (23.08±1.19 kg/m²) for the control individuals, a general questionnaire were done for all patients and control for diagnosis excluded disease and any treatment that effect on obesity, the investigations that were done include : fasting blood sugar with hormonal testing is performed by ELISA kits examining Serum Insulin, Glucagon, Leptin and Ghrelin and the results of this study showed a significantly higher difference in percentage (p value ≤ 0.05) between study and control groups concerning education and gender. Regarding investigation there is significantly higher difference in percentage (p value ≤ 0.05) between study and control groups in parameters of fasting blood sugar, HOMA IR, Leptin and Insulin, while no significant difference (p value ˃ 0.05) in percentage between study and control for Ghrelin hormone and Glucagon hormone, so the conclusion of the results of this study support the evidence that obesity associated with Insulin Resistance, high level of Insulin and Leptin hormones and low concentrations of Ghrelin hormone, while it did not found a link with Glucagon hormone

دراسة فيروس نظير الانفلونزا وبكتريا المسبحيات القيحية مع التهاب الاذن الوسطى القيحي في الاطفال == Study of Parainfluenza virus and Streptococcus pyogenes with suppurative otitis media in children

Author name: ايام محمد صالح علي العامود
Supervisor name: جواد كاظم طراد الخفاجي | غانم عبود المولى
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: هدفت هذه الدراسة الى التحري عن دور فيروس نظير الانفلونزا وبكتريا المسبحيات القيحية Streptococcus pyogenes في الاطفال الذين يعانون من التهاب الاذن الوسطى القيحي . جمعت 200 عينة (ثلاث مسحات لكل مريض تضمنت مسحة من افرازات الاذن ومسحة من افرازات الانف لدراسة الفيروس ومسحة من افرازات الاذن لدراسة البكتريا و50 عينة دم) من 50 مريض يعانون من التهاب الاذن الوسطى القيحي احيلوا الى مستشفى الحلة التعليمي في محافظة بابل للفترة من شباط (2016) لغاية ايار (2016). والذين يعانون من التهاب الاذن الوسطى. وتضمنت الدراسة 32 عينة ماخوذه من اشخاص اصحاء كمجموعة سيطرة وتم تقسيمهم الى ست مجاميع عمرية بنفس طريقة تقسيم مجاميع المرضى. شملت الدراسة اربعة اجزاء رئيسية : اولا التشخيص الفيروسي اعتمد على التقنيات المتقدمة (العزل الاولي باستخدام فحص التالق المناعي المباشر لتحديد وتمييز الانواع الثلاثة لفيروس نظير الانفلونزا 1,2, and 3 والتشخيص الجزيئي بواسطة استخدام فحص تفاعل سلسلة انزيم البلمرة بالوقت الحقيقي لتحديد وتمييز الانواع الاربعة للفيروس1,2,3, and 4 وتم استخدام المجهر الالكتروني النفاذ لمشاهدة جزيئة الفيروس . والجزء الثاني فحص البكتريا باستخدام فحوصات الكيموحيوية وفحص Vitek 2 system وتم التحري ايضا عن انزيم الهيمولايسين حيث كانت جميع العزلات منتجه لهذا الانزيم . التشخيص الجزيئي للكشف عن وجود الجين mga بواسطة تقنية سلسلة تفاعل انزيم البلمرة .الجزء الثالث شمل وجود الفيروس والبكتريا في عينات الاذن للمرضى المصابين بالتهاب الاذن الوسطى . الجزء الرابع تضمن دراسة مناعية لمعرفة دور الحركيات الخلوية IL - 6, TNF - α, IFN - α, CD8, and CD56))عند الاصابة بفيروس نظير الانفلونزا بواسطة فحص الامتصاصية المناعي المرتبط بالانزيم وباستخدام تقنية التالق المناعي المباشر لفيروس نظير الانفلونزا بانواعه الثلاثة (hPIV 1,2,3) كانت نسبة الاصابة 64% (اي 32 طفلا من اصل من اصل50) وعند استخدام فحص تفاعل سلسلة انزيم البلمرة بالوقت الحقيقي ( (RT - PCR وجد ان نسبة الاصابة بفيروس نظير الانفلونزا بانواعه الاربعة (hPIV_1,2,3 and 4) 44% ( اي 22 من 50) تضمنت الدراسة استخدام المجهر الالكتروني النفاذ لرؤية جزيئة فيروس نظير الانفلونزا في افرازات الاذن . اظهرت نتائج التشخيص البكتيري ان نسبة الاصابة بالمسبحيات القيحية هي 14%(7 من 50) بعد زرعها على وسط اكار الدم وحضنت لمدة 24 ساعة بدرجة 37 وتم فحصها بواسط المجهر الضوئي بعد تصبيغها بصبغة كرام , تم التشخيص بواسطة استخدام فحص Bacitracin sensitivity وفحص انتاج انزيم الهيمولايسين على وسط الدم بواسطة فحوصات الكيموحيوية وفحص Vitek 2 systemاظهر التشخيص الجزيئي للكشف عن وجود mga جين ان جميع العزلات تحتوي على هذا الجين اي نسبة 100% .كما اظهرت الدراسة ان نسبة وجود الفيروس مع البكتريا في في سوائل الاذن بنسبة (16%)( . 4 وكانت نسبة وجود الفيروس (72%) 18وشملت الدراسة ايضا فحص الحركيات الخلوية بواسطة فحص الامتصاصية المناعي المرتبط بالانزيم واظهرت النتائج ارتفاع مستوى السايتوكينات في مصل مرضى التهاب الاذن الوسطى مقارنة مع الاشخاص الاصحاء وكان اعلى مستوى لانترليوكين 6 في امصال مجموعة المرضى المصابين بفيروس نظير الانفلونزا للذكور والاناث هو) 88.24 )و (100.95) 1Pg/ml على التوالي . في حين كان اعلى مستوى لعامل النخر الورمي نوع الفا في امصال مجموعة المرضى المصابين بفيروس نظير الانفلونزا للذكور والاناث هو (99.35 ) و(109.81 ) Pg/ml على التوالي. وكان اعلى تركيز لانترفيرون الفا في امصال مجموعة المرضى المصابين بفيروس نظير الانفلونزا للذكور والاناث هو( 217.16) و(( 197.84 Pg/ml على التوالي . واظهرت النتائج ان تركيز الواسمين المناعيين CD8 وCD56 ان تركيزهما اعلى في مصل مرضى التهاب الاذن الوسطى مقارنة مع الاشخاص الاصحاء , اظهرت النتائج ان تركيز CD8 في امصال مجموعة المرضى المصابين بفيروس نظير الانفلونزا للذكور والاناث هو ((11.46±1.49 و(14.76±1.73) ng/ml على التوالي . في حين كان تركيز CD65 في امصال مجموعة المرضى المصابين بفيروس نظير الانفلونزا للذكور والاناث هو (12.82±1.62 )و (10.59±1.19) ng/ml على التوالي | This study aimed to detect the role of of parainfluenza virus and Streptococcus pyogenes in children suffering from suppurative otitis media. A total of two hundred sample (three swab for each patients include ear swabs , nasopharyngeal secretion for viral study and ear swab for bacterial study and 50blood sample) , were collected from 50 patients suffering from suppurative otitis media attending to AL - Hilla Teaching Hospital in Babylon - Iraq during the period from February 2016 to May 2016. The study includes 35 samples obtained from healthy subject as control group that classified to six group according to age in similar way of patient's with parainfluenza virus infection group years old The study includes four main parts .First one is the viral diagnosis based on relied diagnostic procedure ( Primary detection of parainfluenza virus in ear discharge by direct Immunofluorescence for parainfluenza virus 1, 2 and 3 types, molecular diagnosis by Real - Time PCR technique for the qualitative detection and differentiation of Parainfluenza Virus 1, 2, 3, 4 and diagnosis of parainfluenza virus by transmission electron microscope. The second part includes the bacterial diagnostic based on relied diagnosis procedure (using conventional biochemical reaction and commercial kit (Vitek 2 system). The heamolysis on blood agar was also observed in all isolates. Molecular detection of mga virulence gene for Streptococcus pyogenes was detected using conventional PCR technique. The third part is Co - infection between GAS and HPIV in OM specimens of children with suppurative OM. The fourth part is an immunological study to investigate the role of cytokines (IL - 6, TNF - α, IFN - α, CD8 and CD56) in HPIV infection by ELISA assay . Direct immunofluorescence for parainfluenza virus 1, 2 and 3 types antigen was positive in 64% (32 out of 50) , when we use Real - time reverse transcription PCR(RT - PCR) the percent of children infection with HPIV1, 2, 3, and 4 was 44% (22 out of 50). The study also include the use of transmission electron microscope for visualized the parainfluenza virus particle in ear swab. Streptococcus pyogenes isolates was detected in 14%(7 from 50) the isolate were confirmed after culturing on the blood agar and incubated for 24 hour at 37ºC, then microscopically by Grams̕̕ staining. Identification was done using commercially prepared bacitracin and the type of hemolysis on blood agar by primary biochemical test and confirmatory identification by vitek2 system compact. Molecular Identification of mga gene for Streptococcus pyogene showed that all Streptococcus pyogenes positive result 100%. The occurrence of Bacterial and viral co - infection in middle ear fluids which have been observed in 16% (4 out of 50 cases). HPIV was identified as a single agent in ear swab in 72%(18 out of 50). The study include estimation of some immunological parameter include (IL - 6, TNF - α, IFN - α , CD8 and CD56 ) using ELISA and revealed elevation the concentration of cytokines in sera of otitis media patients in comparison with healthy control groups. The concentration of IL - 6 is higher in sera of otitis media patients with parainfluenza virus than healthy control group. The high level of IL - 6 Pg/ml in otitis media patients for male and female was (88.24) and (100.91) Pg/ml respectively. Also level of TNF - α Pg/ml in otitis media patients for male and female was (99.3) and (109.8) Pg/ml respectively . The level of IFN - α Pg/ml in otitis media patients for male and female was (217.16 )and (197.84 )Pg/ml respectively. The results also show elevation concentration of CD8 and CD56 in sera of otitis media patients with parainfluenza virus than healthy control group. For CD8 ng/ml in otitis media patients for male and female was(11.46) and (14.76)ng/ml respectively. The level of CD56 ng/ml in otitis media patients for male and female was (12.82) and (10.59)ng/ml. respectively.

الكشف عن اللولبية البوابية في خزعة المعدة ودراسة مستوى P53 وطفرات مورثة Bax المرتبطة بالقرحة الهضمية == Detection of Helicobacter pylori in Gastric Biopsy and Study the Level of P53 and Bax Gene Mutations Associated With Peptic Ulcer

Author name: اصيل هاشم راضي السعبري
Supervisor name: محمد صبري عبد الرزاق السعيد | مشتاق عبد العظيم وتوت
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: اللولبية البوابية هي بكتريا سالبة لصبغة كرام, الذي تصيب غالبية سكان العالم وتسبب امراض مختلفة مثل التهاب المعدة المزمن, القرحة الهضمية وسرطان المعدة. في حين ان غالبية الناس المصابين بالبكتريا اللولبية لا تظهر عليهم اعراض مرضية. ان العوامل الرئيسية التي تحدد تطور الامراض ذات الصلة بالبكتريا اللولبية قد تكون ضراوة البكتريا, وعوامل المضيف الوراثية والبيئية.الهدف من هذه الدراسة هو الكشف عن اللولبية البوابية في انسجة المعدة ودراسة عوامل الضراوة الرئيسية لهذا الممرض والعوامل الوراثية للمضيف في المرضى الذين يعانون من اعراض اصابات المعدة والاثني عشري. وتشمل الطرق الجزيئية ايضا تفاعل سلسلة البلمرة (PCR) للكشف عن جينات التشخيص والضراوة لبكتريا اللولبية البوابية وتقنية (SSCP) تم القيام بها للكشف عن الطفرات الجينية ل P53 وال Bax جين التي قد تترافق مع عدوى اللولبية البوابية.بلغ العدد الكلي للنماذج (الخزعات) المعوية 180 نموذج. فقط 92 خزعة معدة (51 ٪) اعطى نتيجة ايجابية لللوليبيات البوابية (Helicobacter pylori ) للتشخيص بواسطة التقنية الجزيئية, مع ذلك من بين هذه النتائج الايجابية 60% منها اعطى نتيجة ايجابية للزراع, التي تعتمد على الميزات الكيميائية الحيوية. كما تم اخذ 100 عينة مصل الدم من افراد اصحاء مع عدم وجود تاريخ عدوى بالبكتريا اللولبية كمجموعة سيطرة ونتائج اختبار الاجسام المضادة على اساس (اختبار المصلية) اعطت نتائج سلبية للبكتريا اللولبية.قد تم ملاحظة وجود تكرار عالي للولبية البوابية بالتهاب المعدة المزمن الذي يشكل 88٪ بينما التكرار القليل كان مقداره 3٫3٪ لسرطان المعدة في حين ان 8٫7٪ كان لقرحة الاثنى عشري. وقد كان التكرار العالي لعدوى اللولبية البوابية بين المصابين الذكور اكثر من الاناث, ويعود سبب ذلك لعدة عوامل مثل (متوسط العمر الاجتماعي والاقتصادي ونقص التغذية وسوء النظافة) ويعتبر التدخين احد العوامل الاضافية المرتبطة مع انتشار عدوى (اللولبية البوابية ) بسبب السلوكيات غير الصحية المرافقة للتدخين , والتي قد تشمل نقل البكتيريا من خلال اللعاب بين المدخنين. من جهة اخرى اظهرت النتائج ان معدل العدوى العالي للمجموعة العمرية (31 - 50) سنة الذي تم تسجيله كان 44٫6٪. علاوة على ذلك فان الكشف عن اللولبية البوابية بتقنية سلسلة تفاعل البلمرة PCR)) قد اجريت على جميع انواع خزعات المعدة وجين (ure C ) اضافة الى جين (ure A ) اللذان يستخدمان كعلامات للتشخيص التاكيدي للولبية البوابية من خلال استخدام (primers ) خاص لتقنية PCR. وضحت النتائج ان 84٫8٪ و73٫9٪ للولبية البوابية كانت ايجابية لكلا الجينين. للعينات التي اعطت نتائج ايجابية (للتضاعف الجيني amplification ) بواسطة (PCR ), كان 56 عينة ما يمثل (60٪) قد اعطت استجابة لنتائج الزرع. اضافة الى التضاعف بواسطة PCR لعلامات جين (ure C ) وجين (ure A ). اضافة الى ذلك ,المعدل الايجابي للولبية البوابية للخزعات تحت الاختبار كان 51٪ بالاعتماد على الكشف الجزيئي المباشر بواسطة (PCR) باستخدام جين (ure A) وجين (ure C ). علاوة على ذلك, تم فحص جين (cag A) لكل عينات اللولبية البوابية التي تم عزلها. اشارت النتائج الى ان65 عزلة (70٫6٪) كانت ايجابية لتضاعف (PCR ) للجين من نوع cagA) ) حيث ان عزلة 56 (60٫8٪) كانت ايجابية لتضخيم (PCR ) للجين من نوع (cag E ). من بين النتائج الايجابية التي تم عزلها 49 عزلة (53٫3٪) كانت قد اعطت نتائج ايجابية للجين من نوع (cag A ). كذلك وجد تكرار الجين (vac A ) مقداره في الدراسة الحالية 68٫5٪ (63/92). اضافة الى كل اللولبيات البوابية الايجابية لخزعة المعدة 49 (53٫3٪) اظهرت اشارة كاملة للجينات نوع (cagA, cagE وvacA (. بالنسبة للعينات المعدية المتبقية 27 عينة (30٫4٪) التي تحوي سلالات سلبية كانت سلبية للجين (cag E). وقد تم تحديد طفرات جين (p53) في الاكسونات 5 و6و 7 و8 باستخدام طريقة SSCP. ومع ذلك تم استخدام PCR لتضخيم الاكسونات 5 و6 و7 و8 للجين (p53) التي من المعروف انها بقع ساخنة طافرة .تحليل PCR - SSCP يكشف تعديلات في الجين (p53) في عدة اكسونات. حيث ان ستة عشر من التعديلات في الاكسون E5A , سبعة عشر التعديلات في الاكسون E5B6A, وكذلك سبعة عشر التعديلات في الاكسون E7 وتعديل واحد فقط في الاكسون E6B لكن لم يظهرتعديل في الاكسون E8 في الجين (p53). بنفس الاسلوب ان تحليل PCR - SSCP كشف عن تعديلات في جين bax في الاكسونات E1 وE4 وE6. ويظهر ذلك في الاشكال. فيما يخص الاكسون 1 في bax يمكن ملاحظة وجود 6 نماذج فقط تعطي طفرات موضع ايجابية للجين. قد يعزى ذلك الى اللولبية البوابية التي تحفز طفرة bax من خلال قابليتها على انتاج بروتين cag A الذي له القابلية على تغيير التسلسل الجيني والوظيفة. واستنتجنا الى ان التشخيص الجزيئي قدم دليلا توكيديا على وجود اللولبية البوابية في عينات المعدة. ايضا قد تؤثر السلالات الاكثر ضراوة على تحفيز طفرات جينية في جينات ال p53 وال bax. | Helicobacter pylori is a gram - negative bacteria which infects a majority of the world population. It causes various diseases such as chronic gastritis, peptic ulcer and gastric cancer. While majority of the people infected with H. pylori is asymptomatic. The main factors, which determine the development of H. pylori related diseases might be bacterial virulence, host genetic and environmental factors.The aim of this study is detection of H. pylori in gastric tissue and study the main virulence factors of this pathogen and host genetic factors in patients with gasteroduodenal manifestation. Molecular methods include polymerase chain reaction (PCR) for diagnosis and virulence genes of H. pylori and single strand confirmation polymorphism (SSCP) technique was done to detect the p53 and bax genes mutation may be associated with H. pylori infection. In this study, 180 patient were included, only 92 gastric biopsies (51%) gave positive for the presence of H. pylori diagnosed by direct molecular technique. Among these positive result, 60% gave positive results in cultivation based on biochemical features. In addition, 100 serum samples were taken from healthy individuals, with no history of H. pylori infection as a control group and the results of antibody based test (serological test) were negative for H. pylori.In this study, the high frequencies of H. pylori were observed for chronic gastritis, which constituted 88% while low frequencies were 3.3% for gastric cancer, whereas 8.7% for duodenal ulcer.Also, the highest frequencies of H. pylori infection were found in male patients in comparison to female. On the other hand, the results showed that the high significant infection percentage 44.6%, among age group ranging from 31 - 50 years. Moreover, detection of H. pylori by Polymerase Chain Reaction (PCR) technique is performed on all gastric biopsy. ure C as well as ure A genes are used as markers for confirmatory diagnosis of H. pylori through using specific primers of PCR technique. The results show that 84.8% and 73.9% of H. pylori are positive for both genes, respectively. Among samples with positive result for PCR amplification, 56 samples (60%) also had positive culture result. Besides, the PCR amplification of ureC and ureA markers. Also, the rate of positive H. pylori in the tested biopsies was 51% depending on direct molecular detection by PCR using the ureA and the ure C genes.In addition, cag A gene is investigated in all H. pylori isolates. The results show that 65 isolates (70.6%) are positive for PCR amplification of cagA gene whereas 56 isolates (60.8%) are positive for PCR amplification of cag E gene. Among of these positive isolates, 49 isolates (53.3%) give positive result for cag A gene. The frequency of the vacA gene found in the present study is 68.5% (63/92).Furthermore, among of all H. pylori positive gastric biopsy, 49 (53.3%) reveal full signals of cagA, cagE, and vacA. The remaining 27 (30.4%) gastric biopsies, harboring cagA - negative strains, are PCR negative for cagE.Mutations of the p53 gene in exons (5,6,7 and 8) are identified by PCR - SSCP method. However, PCR is used to amplify exons 5,6,7 and 8 of p53 gene which are known to be mutational hot spots. PCR - SSCP analysis has detected alterations in the p53 gene in several exons. Where sixteen alterations in exon E5A, nineteen alterations in exon E5B6A, seventeen alterations in exon E7 and only two in exon E6B but no alteration is seen in exon E8 of P53 gene.In the same way, PCR - SSCP analysis detected alterations in Bax gene where only 17% of positive samples gave alteration in the sequence of Bax gene in exons E1, E4 and E6. Regarding exon 1 of Bax gene, it was seen that only 6 samples gave positive gene locus mutation. It conclude that the molecular diagnosis gave an evidence and confirmatory guide on the existence of H. pylori in gastric samples. Also the more virulent strain may be affected on the stimulation of p53 and bax genes mutation.

دراسة بكتريولوجية وجزيئية لبكتريا Proteus mirabilis معزولة من عينات مختلفة == Bacteriological and Molecular Study of Proteus mirabilis Isolated from Different Clinical Samples

Author name: ختام فاضل عباس
Supervisor name: جواد كاظم الخفاجي | ميساء صالح الشكري
General topic: Medicine
Specific topic: Microbiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: تلخصت هذه الدراسة بجمع وتشخيص P. mirabilis حيث عزلت وشخصت سبعة عشر عزلة (12.6%) عائدة الى بكتريا P. mirabilis من 135 عينة جمعت من مصادر مختلفة من المرضى المراجعين الى مستشفى الحلة الجراحي خلال الفترة من (تشرين الاول 2014 الى شباط 2015). عدد ونسبة العزلات التي تم الحصول عليها من مرضى المجاري البولية 11(64%)و التهاب الاذن 3(17%) . بالاضافة الى ذلك نسبة العزلات التي تم الحصول عليها من مرضى الاسهال والجروح والتهابات المهبل من كل حالة 1(5.9%). العزلات التي تم الحصول عليهزارعت في اوساط خاصة وشخصت بايوكيميائيا وبكتريولوجيا.من خلال التحري عن بعض عوامل الضراوة وجد ان جميع العزلات (100%) قادرة على انتاج الهيمولايسين ، اليورييز، البروتسين وظاهرة الانثيال. تم الكشف على انتاج البيتالاكتميزلجميع العزلات المقاومة لمضادات البيتا لاكتام بحسب طريقة Rapid Iodiometric وبينت نتائج الدراسة ان16(94.1%) من العزلات منتجة للبيتالاكتميز. اظهرت نتائج الدراسة قابلية جميع العزلات على مقاومة بعض المضادات الحياتية فقد بينت النتائج بان كل العزلات كانت مقاومة كليا 17(100%) الى Imipenem كما ان اغلب العزلات كانت حساسة الى Ertapenem حيث ان نسبة المقاومة فقط 3(17.6%). علاوة على ذلك مقاومة العزلات لمختلف المضادات الحياتية فحصت وظهرت ان العزلات مقاومة بنسب مختلفة 14(82.3%) منهم اعطت مقاومة الى Amoxicillin وCefotaxime , 9 (52.9%) منهم اعطت مقاومة الى Amoxiclave, 11(64.7 %) منهم اعطت مقاومة الى Ceftriaxone و4(23.5%) منهم اعطت مقاومة الى Cefepime Clavulanic acid.لجينات المشفرة عوامل الضراوة لبكتريا P. mirabilis كشفت باستخدام تقنية تفاعل البلمرة المتسلسل PCR)). ظهرت النتائج ان كل عزلات البكتريا اعطت نتيجة موجبة للجين rsbA, luxS, pm1, mrpA ,ureC مع عدد ونسبة ,(53%)9 7(41%), 8(47%),,(35%)6 ,(18%)3 بالتعاقب. | This study is devoted to isolation and identification of Proteus mirabilis; 17 isolates of P. mirabilis have been isolated and identified out of one hundred thirty five clinical specimens obtained from patients attending to Hilla teaching Hospital during a period from October 2014 to February 2015. The number and percentage of isolates obtained from patients with urinary tract infections was 11(64.7%), and ear infection 3(17.6%). Other isolates obtained from patients with diarrhea, wound and vaginal infection that each case has percentage 1(5.9%). The isolates obtained have been cultured in selective media and biochemically assay. Some virulence factors of all isolates are studied, and the results showed that all bacterial isolates 17(100%) produced hemolysin, urease, Bacteriocin (proticin) and swarming. The detection of β - lactamase production is performed according to Rapid Iodometric Method and the result is shown that 16(94.1%) of isolate produced beta - lactamase. Antibiogram of P. mirabilis isolates has been studied and it has been found that all isolates were entirely resistant to Imipenem 17(100%), while most of the P. mirabilis isolates were sensitive to Ertapenem so the resistant only 3(17.6%). Furthermore, the resistance of isolates to a variety of antibiotics has been investigated and found that these isolates have been resistant to more than one antibiotic : 14(82.3%) to Amoxicillin and Cefotaxime, also 9(52.9%) of them were resistant to Amoxiclave, 11(64.7%) of them were resistant to Ceftriaxone and 4(23.5%) of them were resistant to Cefepime Clavulanic acid. Virulence factors encoding genes of P. mirabilis is detected by using polymerase chain reaction PCR. It is found that all bacterial isolates gave positive result for ureC, mrpA, pm1, luxS and rsbA with number and percentage 3(18%), 6(35%), 7(41%), 8(47%), 9(53%) respectively

تقييم الرعاية الذاتية لممارسات الامهات قبل الولادة في مدينة الحلة == Assessment of self - care Practices during Prenatal Period among Mothers In Hilla City

Author name: نور موسى كاظم البياتي
Supervisor name: سلمى كاظم جهاد
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: دراسة وصفيه تحليليه اجريت على عينه غير احتماليه, غرضيه, من اجل تحقيق الاهداف وتقييم ممارسات الرعاية الذاتية للامهات قبل الولادة في مدينة الحلة . ابتداء من 1 الفترة من ديسمبر 2014 الى 3 اغسطس 2015. , تم اختيارهم عشوائيا من مجتمع الدراسة والتي تتكون من (150) امراه حامل ومن خلال مراجعة شاملة من المؤلفات ذات الصلة والدراسات السابقة ، تم بناء الاستمارة استبيانيه لغرض الدراسة. تم تنفيذ عملية جمع البيانات من خلال استخدام اداة الدراسة والاستبيان من الفترة (2 يناير 2015 الى 31 مارس 2015) من اجل تحديد ما اذا تحققت اهداف الدراسة ام لا، واستخدمت نوعين من طرق تحليل بيانات الدراسة. اجريت دراسة تجريبية لتحديد ثبات اداة الدراسة لقياس المتغيرات, (15) ام حامل اختيرت بنفس معايير العينة بشكل عشوائي للمشاركة في جمع البيانات. وتم استبعادها من العينة الاصلية اجريت من الفترة الثالث من يناير ولغاية الحادي عشر منه لسنة 2015 , تم تحليل البيانات للوصول الى النتائج بواسطه استخدام التحليل الوصفي للعينه والتي تتضمن الوسائل الوصفية مثل (التكرارات , النسب المئوية , الوسط الحسابي , الوسيط والانحراف المعياري ) كوسائل تحليلية مثل مربع كاي تشير النتائج من خلال المصادر الى وجود علاقة معنوية عالية بين الخصائص الديموغرافية التقييم العام للممارسات خلال فترة الحمل مثل (العمر المستوى التعليمي نوع العائلة حجم العائلة والمستوى الاقتصادي ) عند قيمة معنوية اقل ,010 ونتائج ذات معنوية عالية فيما يخص (العمل , محل الاقامة) عند قيمة معنوية اقل من,05 0 وتشير النتائج الى وجود علاقة ذات معنوية عالية بين تاريخ الام الانجابي وتقييم ممارسات الرعاية الذاتية والذي يشمل (عمر الحمل الاسقاط ,عدد الولادات الميتة ,التعرض لوسائل الاعلام) عند مستوى معنوي اقل من 0,01وكانت ذات قيمة معنوية (عدد الولادات الميتة , الزيارات الروتينية) اقل من 05 0.وعلاوة على ذلك لا توجد علاقة ذات دلالة معنوية (عدد الولادات الحية, عدد مرات الحمل) تحت قيمة معنوية 0.05 استنتجت الدراسة ان العينة وصلت الى مستوى جيد من الممارسات فيما يخص ( التغذية , النشاط البدني ,النظافة الشخصية , الراحة والنوم والممارسات الاخرى) . اوصت الدراسة بتركيز الجهود على ممارسة النشاط البدني في هذي الفترة وتشجيع وسائل الاعلام النساء الحوامل لمتابعة البرامج الغذائية | A descriptive design study was carried - out in order to achieve the early stated objectives. And to assess the self - care practices during prenatal period among mothers in Hilla city starting from the period 1st of December 2014 to the 3rd of August 2015. A non - Probability was performed convenient sampling, which consists of (150) pregnant women . as randomly selected from the general population. Through an extensive review of relevant literature and previous studies, a questionnaire was constructed for the purpose of the study . The data collection was performed through use of the study instrument and the questionnaire for the period (January 2nd 2015 to March 31th of 2015). In order to determine whether the objectives of the study were met or not, two statistical approaches were used for analyzed the data of the study. A pilot study was conducted in order to determine the reliability of the study instrument which were used for measuring the variable of the study, (15) women who had the same criteria of the study sample were selected randomly to participate in the collection of the data. The sample of pilot study was excluded from the original sample of the study . The study was conducted (from the period January 3rd 2015 to January 11th 2015) . Data analysis approaches were used in order to analyze and assess the results of the study under application of the descriptive data analysis approach. The descriptive data analysis consisted tables such as : (Frequencies (F), Percentages (%), Arithmetic, Mean, Mean of Scores, Standard Deviation) & Inferential data analysis approach such as ( chi - square test) The findings of the study indicated that through result of the study there was a high significant association between the demographical data with their overall assessment of the self - care practices during prenatal period with their (age, educational level, type of the family, family size, economic status) at p - value less than 0.01, and there was a significant (occupational status, Residency) at P - value less than 0.05. The histories of the mother with their overall assessment of the self - care practices during prenatal period that there a high significant association between the histories of the mother with their overall assessment of the self - care practices during prenatal period with their (gestational age, abortion, number of dead, exposure to mass media) at P - value less than 0.01, there was a significant (number of dead, and routine visits) at p - value less than 0.05. Moreover no - significant association with their (Gravida , Para) at P - value more than 0.05. The study concluded that sample showed a good level of practices during this period in regard to (nutritional , physical activity , personal hygiene , rest and sleep & other practices). The study recommended that efforts must ensure the practices of exercises in this period, mass media must encourage pregnant for following the dietary guides.

دراسة النمط المناعي وقابلية الاصابة بالعدوى الميكروبية لدى ذوي السمنة البالغين == Study The Immune Profile & Susceptibility to Some Microbial Infections in Obese Adults

Author name: فؤاد قاسم جبير الزيادي
Supervisor name: محمد عبد كاظم حسن السعدي | هديل فاضل فرهود
General topic: Medicine
Specific topic: Microbiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: هدفت هذه الدراسة الى توضيح العلاقة بين البالغين الذين يعانون من السمنة والتعرض للعدوى الميكروبية من خلال تقدير المعايير المناعية مثل (IFN - γ & IL - 2)، عناصرcomplement system (C3, C4) , وقياس فعالية الخلايا المناعية الالتهامية من خلال الكشف عن الاصابة بـ Streptococcus pyogenes وMeasles virus. انجز هذا العمل على 50 شخصا من ذوي السمنة البالغين (11 ذكرا و39 انثى) تتراوح اعمارهم من (20 - 60) عاما قاموا بزيارة قسم التغذية في مستشفى مرجان التعليمي في محافظة بابل خلال الفترة من نوفمبر 2014 الى يناير 2015، و30 شخصا اخرين اصحاء لا يعانون من السمنة (21 ذكور و9 اناث) تتراوح اعمارهم من (22 - 42( عاما. وتم قياس مؤشر كتلة الجسم (BMI) لكل فرد من ذوي السمنة والاصحاء. تم جمع عينات الدم من كلا المجموعتين لقياس فعالية الخلايا الالتهامية، والمعايير المناعية الاخرى مثل (IFN - γ & IL - 2)، وعناصر complement system (C3, C4), والكشف عن الاصابة بـ Streptococcus pyogenes وMeasles virus بطريقة الامتزاز المناعي المرتبط بالانزيم. اظهرت النتائج ان تركيز (IL - 2) عند ذوي السمنة اقل بكثير وبشكل معنوي عن الذين لا يعانون من السمنة (P˂0.05) ، ولم يظهر تركيز IFN - γ)) في مجموعة ذوي السمنة انخفاضا معنويا (p>0.05) عن تركيزه عند الاصحاء. وكانت عناصر complement system (C3, C4)مرتفعة عند ذوي السمنة وبشكل عالي المعنوية (p˂0.001) عن مجموعة الاصحاء الذين لا يعانون من السمنة، ولكن فعالية الخلايا الالتهامية اظهرت انخفاضا عالي المعنوية (p˂0.001) عند مجموعة ذوي السمنة (6.1٪) مقارنة بمجموعة الاصحاء (10.6٪)، وزيادة تراكيز كل من ASO وanti - measles virus - IgG وبشكل عالي المعنوية (p˂0.001) عند ذوي السمنة مقارنة بالاصحاء | This study aimed to clarify the relationship between obese adults & susceptibility to microbial infections by evaluating the parameters of cytokines (IFN - γ & IL - 2), complement components (C3 & C4), and phagocytic index using of Anti - Streptococcus pyogenes Ab and Anti - Measles virus - IgG Ab as indicators of infections. This work was applied on 50 obese adults visited to the center of nutrition in Marjan hospital in Babylon province from November 2014 to January 2015, and 30 non - obese apparently healthy as controls. Obese adults consist of (11 males and 39 females) with age range 20 - 60 years, while 30 apparently health controls consist of (21 males and 9 females) with age range 22 - 50 years. Body mass index (BMI) for all subjects obese & controls was estimated. Blood samples were collected from obese group and control group to estimate phagocytic index, and ELISA test for cytokines (IFN - γ & IL - 2), complement components (C3 & C4), and detection of measles - IgG antibody and anti - streptolysin O antibody. IL - 2 concentration in obese adults was significantly lower than non - obese adults (p˂ 0.05), and no significant decreased (p>0.05) of IFN - γ in obese group, the complement components (C3 &C4) in obese adults were a highly significant than controls, but the phagocytic index showing there is a highly significant decreased (p˂0.001) in activity of neutrophils of obese adults (6.1%) compared to control group (10.6%), ASO and Anti - measles - IgG concentrations increased in obese adults with a highly significant (p˂0.001) as compared to controls. This findings can be concluded as that obese subjects have low levels of immune system and more susceptible to be infected with microbial infections

التشخيص الكهربائي المبكر لاعتلال الاعصاب القحفي غير السريري لدى مرضى السكري المصابين او غير المصابين باعتلال الاعصاب المحيطيه == Early Electrodiagnosis of Subclinical Cranial Neuropathy in Diabetic Patients with or without Peripheral Neuropathy

Author name: ولاء فاضل جلال الحسناوي
Supervisor name: سعد مرزة حسين الاعرجي | كريم مصحب التميمي
General topic: Medicine
Specific topic: Physiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: داء السكري من النوع الثاني هو مشكلة صحية منتشرة على نطاق واسع ويمتاز بمضاعفات عديدة تصيب الاوعية الدموية مما يؤدي الى ارتفاع معدلات الاعتلال والوفيات. الاعتلال العصبي المحيطي السكري هو اكثر المضاعفات شيوعا لداء السكري من النوع الثاني ، وفي الغالب يكون بشكل اعتلال الاعصاب القاصي المتناظر والذي يكون على هيئة قفازات وجوارب. ارتفاع السكر في الدم هو العامل المسبب الرئيسي لاعتلال الاعصاب المحيطية لدى مرضى السكري. اعتلال الاعصاب القحفية عادة تظهر مع الاعتلال العصبي المحيطي السكري اما سريريا او في شكل تحت السريري. الهدف الرئيسي من هذه الدراسة هو تقييم لدور منعكس الطرفة في التشخيص المبكر لاعتلال الاعصاب القحفية لدى مرضى السكري من النوع الثاني مع او بدون اعتلال الاعصاب. الطرق والاساليب : اجريت الدراسة خلال الفترة من شهر كانون الثاني الى شهر اب 2014. شملت الدراسة 83 مريضا ممن يعانون من داء السكري النوع الثاني ضمن الفئة العمرية من 35 - 69 سنة. اعتبر المرضى الذين يعانون من الاعراض السريرية لضعف الاعصاب الطرفية والذين لديهم تخطيط الاعصاب الكهربائي غير طبيعي بانهم مرضى اعتلال الاعصاب المحيطية السكري (61 مريضا)، في حين اعتبر المرضى الذين لايعانون من ضعف الاعصاب الطرفية وتخطيط الاعصاب الكهربائي لديهم كان طبيعيا بانهم لا يشكون من اعتلال الاعصاب المحيطية السكري ( 22 مريضا). شملت الدراسة ايضا اشخاص لا يعانون من اي مرض تتناغم اعمارهم وجنسهم مع المرضى المشمولين بالدراسة سميت مجموعة السيطرة(60مريضا).وقد خضع المرضى ومجموعة السيطرة المشمولين بالدراسة الى التقييم الكامل الذي شمل : التقييم السريري (التاريخ والفحص)، وتقييم الكيمياء الحيوية (قياس سكر الدم بعد الصيام، الهيموجلوبين السكري، قياس نسبة دهون الدم) وتخطيط الاعصاب الكهربائي الذي يشمل دراسات التوصيل الحسية والعصبية الحركية NCS)) مع منعكس طرفة.النتائج : وجدت الدراسة ان مرضى السكري لديهم تاريخ عائلي ايجابي، انخفاض المستوى التعليمي وارتفاع مؤشر كتلة الجسم بالمقارنة مع مجموعة السيطرة. مرضى السكري مع اعتلال الاعصاب المحيطية لديهم رابطة كبيرة مع زيادة العمر (القيمة P <0.01) ، وكبيرة للغاية مع مدة المرض (0.007=P)، واهمية عالية مع الفرق في مؤشر كتلة الجسم (قيمة P <0.01) بالمقارنة مع مرضى السكري من دون اعتلال الاعصاب المحيطية . وكان مرضى السكري المصابون باعتلال الاعصاب المحيطية علاوة على ذلك لديهم ضعف السيطرة على نسبة السكر في الدم التي تعكسها نسبة عالية لقياس سكر الدم بعد الصيام ونسبة الهيموكلوبين السكري, بينما اظهرت صورة الملف الشخصي لقياس دهون الدم قيمة غير مهمه. بينت دراسة التوصيل العصبي (الحسية والحركية) فرق كبير بين الكمون، والسعة، وسرعة التوصيل بين مرضى السكري مع اعتلال الاعصاب المحيطية والذين لا يعانون من هذه الحالة. واظهرت نتائج منعكس الطرفة فرق هام للغاية (قيمة P <0.01) بين مرضى السكري ومجموعة السيطرة.مناقشة : اظهرت نتائج هذه الدراسة ان اعتلال الاعصاب المحيطية السكري يرتبط مع العديد من عوامل الخطورة مثل العمر, مدة المرض، مؤشر كتلة الجسم، وضعف السيطرة على نسبة السكر في الدم . وكشفت الدراسة ايضا ارتفاع معدل اعتلال الاعصاب المحيطية السكري في المرضى قيد الدراسة (73.5٪). اعتلال الاعصاب القحفية تحت الاكلينيكي موجود ايضا في المجموعة قيد الدراسة بغض النظر عن وجود او عدم وجود اعتلال الاعصاب المحيطية السكري. وقد تبين ذلك من خلال منعكس طرفة غير طبيعي في 44.6٪ من المرضى. كان معظم المرضى الذين يشكون من منعكس طرفة غير طبيعي يعانون ايضا من اعتلال الاعصاب المحيطية السكري (89.2٪) . ووفقا لنتائج هذه الدراسة اعتلال الاعصاب المحيطية السكري يزيد من فرصة وجود منعكس طرفة غير طبيعي بخمس مرات اكثر، وهو ينبئ باعتلال قحفي تحت الاكلينيكي لوجود نسبة غريبة بين اعتلال الاعصاب المحيطية السكري ومنعكس طرفة شاذ لا ارادي هي 5.29.اعتمد الباحث في تعريب المصطلحات العلمية على : 1 - اطلس التشريح العصبي. الاستاذ الدكتور محمد توفيق الرخاوي. جمهورية مصر العربية - الطبعة الاولى 2000 م.2 - المعجم الطبي الموحد - انكليزي - عربي. رئيس التحرير د. محمود الجليلي - الطبعة الرابعه 2009 م , مطبعة المجمع العلمي العراقي.3 - الموجز المصور لفحص الجهاز العصبي. ترجمة د. عبد الهادي الخليلي - بغداد - 1992 م , د. موريس فان الن ود. روبرت روزنسكي. | Background : Type 2 diabetes mellitus is a widely spread health problem associated with countless micro - and macro - vascular complications leading to rise morbidity . Diabetic peripheral neuropathy (DPN) is the most common complication of type 2 diabetes mellitus and it may presents as distal symmetrical polyneuropathy in which the body involved in gloves and stock pattern. Hyperglycemia is the main causative factor for peripheral neuropathy in diabetic patients. Cranial neuropathies is usually presenting as mononeuropathies coexist with DPN either presented clinically or in subclinical form. The aim of this study is to detect cranial neuropathy in diabetic patients also to evaluate the role of blink reflex for early diagnosis of cranial neuropathy in diabetic patients with or without polyneuropathy. Materials and methods : The study was conducted from January till August 2014. Eighty three patients with type 2 diabetes mellitus within age group of 30 - 69 years were included in the study. Patients who had clinical features of peripheral nerve dysfunction and recognized with abnormal electrophysiological findings of their peripheral nerves were regarded as patients with DPN (61 patients), while those who did not have complains of peripheral nerve dysfunction and with normal electrophysiological study of their peripheral nerves were considered as patients without DPN (22 patients). The study also involved normal healthy persons whose age and gender are harmonized with that of our patients that were deliberated as control group (60 persons). The patients and the controls joined in the study had undergone full evaluation that included : clinical assessment (history and examination), biochemical assessment (measurement of fasting blood sugar, glycosylated haemoglobin, lipid profile) and electrophysiological assessment that included sensory and motor nerve conduction studies (NCS) with blink reflex.Results : The study found that diabetic patients had positive family history, low educational level and high BMI when compared with control. Diabetic patients with DPN had significant (P value <0.01) difference in age(they were older), highly significant (P value =0.007)difference in the duration of the disease(they had longer disease duration), and highly significance (P value < 0.01) difference in BMI(they were obese ) when compared with diabetic patients without DPN.Furthermore diabetic patients with DPN had poor glycemic control reflected by high FBS and HbA1c, while lipid profile picture showed insignificance difference. Nerve conduction study (sensory and motor) showed a significant difference between latency, amplitude, and conduction velocity between diabetic patients with DPN and those without DPN. The results of blink reflex showed highly significant (p value < 0.01) difference between diabetic patients and controls.Discussion : The results of this study showed that diabetic peripheral neuropathy associated with many factors like age, duration of the disease, BMI, and poor glycemic control.The study also revealed a high prevalence of DPN among the studied group (73.5%). Subclinical cranial neuropathies also present in the studied group which was reflected by abnormal blink reflex found in 44.6% of the patients. Most of the patients with abnormal blink reflex had diabetic peripheral neuropathy (89.2%).According to the results of this study, DPN increases the chance of having abnormal blink reflex five times more, which means prophecy of underlying subclinical craniopathy, since the odd ratio between DPN and abnormal blink reflex is 5.29

علاقة الجهد التاكسدي مع بروتين الاوستيوبونتين عند مرضى السكري نوع الثاني الذين يعانون من متلازم الانسداد الحاد == The Relationship between Oxidative Stress and Osteopontin Levels in Patients with Type - II Diabetes Mellitus Presented with Acute Coronary Syndrome

Author name: بشرى عريبي فاضل الحسيني
Supervisor name: طارق حفظي الخياط | منعم مكي الشوك
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: متلازمة الشرايين التاجية الحادة ACS))تمثل مجموعة من الصفات السريرية تتراوح بين الذبحة الصدرية UA))الغير مستقرة وصولا الى احتشاء العضلة القلبية الحاد المصحوب(STEMI) بارتفاع موجة ST - والغير مصحوب بارتفاع موجة ST - (NSTEMI). احتشاء العضلة القلبية الحاد يترافق مع استجابة التهابية موقعيه وجهازية ويعتبر من التعقيدات الرئيسية لمرضى السكري. يزداد انتاج الاوستيوبونوتين في الطبقة الوسطية لشرايين مرضى السكري .يترافق مرض السكري مع ارتفاع الجهد التاكسدي والفقدان الوظيفي لطبقة الخلايا الطلائية . تم جمع العينات من مدينة مرجان التعليمية في محافظة بابل ، خلال الفترة الممتدة تشرين الثاني ٢٠١٤ وشباط ٢٠١٥ . العدد الكلي ١٠٠ شخص منهم ٦٠كمرضى و٤٠مجموعة سيطرة. تم تصنيف مرض السكري الى المجاميع التالية 1 - عشرون مريض مصاب بالسكري بدون اي مضاعفات .2 - عشرون مريض مصاب بالسكري مع وجود ارتفاع الموجه STEMI)ST - ). 3 - عشرون مريض مصاب بالسكري من دون ارتفاع الموجه - ST ( NSTEMI ) تحليل البيانات كشفت عن زيادة معنوية كبيرة في تراكيز (Osteopontin) OPN ، MDA(Malondialdehyde) ونسبة HbA1c في المصل والانخفاض في Catalase))CAT وSuperoxide dismutase))SOD في مجموعات المرضى بالمقارنة مع مجموعه السيطرة .وقد لوحظ وجود زيادة ارتباط ايجابية ذات دلالة احصائية بين OPN وMDA (0.414 = r و8.000 p<) في مجموعتي MI .اظهرت وجود ارتباط سلبي كبير مع SOD (0.461 r= - ، 0.003 p<) وOPN مع وجود ارتباط ايجابي كبير مع نسبة HbA1c (0.336 r=، 0.03 p<) في مجموعتي .MI اظهرت وجود ارتباط سلبي كبير مع SOD(0.362 r = - ،0.02p<) وCAT (0.512 r= - ، 0.01p<) في مجموعتي MI . في مجموعة مرضى السكري النمط الثاني ( Type 2 ) لوحظ ان هناك زيادة كبيرة في نسبة HbA1c ، OPN ، MDA وانخفاض SOD وCAT , هذه النتائج تشير الى وجود مخاطر عالية لامراض القلب في هؤلاء المرضى نظرا لوجود ( ACS) . وحيث ان هنالك زيادة معنوية في التراكيز لكل من OPN ، MDA ، ونسبة HbA1c مع انخفاض بنسبة تركيز SOD في الدم، وتركيز CAT هذا الاختلاف قد يؤدي الى قلة انتاج المواد المضادة للاكسدة وتعزيز انتاج المواد المؤكسدة.في الختام من نتائج الدراسة الحالية ، وجود زيادة كبيرة في تركيز Osteopontin مع وجود الصلة مع مواد الاكسدة وزيادة نسبة HbA1c قد يشير الى ان دور او اهمية ارتفاع السكري في تحفيز مؤشرات التهابية الحادة والتي يمكن اعتبارها كمؤشر لتطور المضاعفات الخطيرة للسكري خاصة على المرضى المصابين باحتشاء العضلة القلبية MI . | The acute coronary syndrome (ACS) encompasses a spectrum of clinical entities, ranging from unstable angina (UA), non - ST - segment elevation myocardial infarction (NSTEMI) to ST - elevation myocardial infarction (STEMI). The acute myocardial infarction(AMI) is associated with a local and systemic inflammatory response , it is a major complication in diabetic patients. Osteopontin (OPN) expression is increased in the media of diabetic arteries . Diabetes is highly associated with oxidative stress and endothelial dysfunction. Subjects were recruited at Merjan Teaching Hospital / Babylon Province, During the period from November, 2014 and February 2015. A total number of 100 persons were classified according to ( 60 ) patients and ( 40 ) control. Diabetes mellitus was classified into the following categories : 1 - Twenty diabetic patients with no complications.2 - Twenty diabetic patients with ST segment elevation ( STEMI).3 - Twenty diabetic patients without ST segment elevation (NSTEMI). Analysis concentration of the data revealed a significant increase of serum (osteopontin ) OPN, ( Malondialdehyde) MDA and HbA1C but decrease in(catalase) CAT and(superoxide dismutase) SOD concentration in the patient groups when compared with those of control groups . A significant positive correlation increase was observed between OPN and MDA (r=0.414, p<0.008) in MI groups . OPN exhibited a significant negative correlation with SOD (r= - 0.461, p< 0.003) and OPN a significant positive correlation with HbA1C (r= 0.336, p< 0.03) in MI groups . MDA exhibited a significant negative correlation with SOD (r= - 0.362, p<0.02) and CAT (r= - 0.512, p<0.01) in MI groups. In type 2 diabetic patients group there is a significant increase in HbA1C, OPN, MDA and low SOD and CAT indicate a high risk for heart diseases in those patients due to the ACS.Where there is an increase of serum OPN, MDA, HbA1C in comparison with decrease of serum SOD,CAT concentration may disturb the antioxidants and enhance the oxidant production. In conclusion of present study results , The significant increase of Osteopentin concentration in relevance to oxidative stress and HbA1C concentration may indicate that the role of hyperglycemia in the induction of this acute inflammatory marker which can be considered as a prognostic indicator of diabetic complications especially diabetic patients with MI.

دراسة التعبير المناعي النسيجي الكيميائي لمستقبلات الاستروجين الفا والبروجستيرون وعلاقتها مع الحالة السريرية المرضية لسرطان الظهارة البولية == Immunohistochemical Study of Estrogen ? and Progesterone Receptors in association with clinicopathological status of urothelial Carcinoma

Author name: احمد اسود حسين
Supervisor name: نعمه حسوني الجبوري | علي حسن التميمي
General topic: Medicine
Specific topic: Diseases
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: سرطان المثانة شائع الحدوث في جميع البلدان في انحاء العالم وانها تمثل اكثر انواع السرطان شيوعا في اوروبا وامريكا الشمالية. سرطان المثانة هو الاول من بين السرطانات شيوعا في العراق وثاني الاورام الخبيثة والاكثر شيوعا في الجهاز البولي والتناسلي في جميع انحاء العالم بعد سرطان البروستات. حالات الاصابة بسرطان المثانة اقل في اسيا مقارنة باوروبا وامريكا الشمالية. الذكور اكثر عرضه للاصابة من الاناث. سرطان الخلايا الانتقالية هو الاكثر حدوثا والتي تمثل نحو 90٪، والنسبة الباقية 10٪ تمثل سرطان الخلية الحرشفية، سرطان الخلايا الغدية، وبعض انواع اخرى نادرة. بداية هناك العديد من البروتينات وكذلك جينات تمت دراستها على سرطان الخلايا الانتقالية للمثانة مثل Ki67،/neu HER - 2 ، CA19.9، CK7، PSA وغيرها. مستقبلات هرمون الاستروجين هي واحدة من فصيلة مستقبلات النووية وعامل النسخ التي تنظم مختلف الوظائف والاعضاء الطبيعي بما في ذلك التنمية، وظيفة الجهاز التناسلي، وتؤثر على انظمة اخرى مثل الهيكل العظمي والقلب والاوعية الدموية. هناك نوعان من مستقبلات هرمون الاستروجين : مستقبل الاستروجين الفا (ERα) ( 60 - 66kD) ومستقبل الاستروجين بيتا (51 - 61kD). يختلف وجود مستقبلات هرمون الاستروجين في الانسجة المختلفة مع وجود اختلافات ملحوظة في التعبير عنها. مستقبلات هرمون البروجستيرون هي واحدة من فصيلة المستقبلات النووية التي وجدت داخل الخلايا، والتي يمكن تفعيلها او تنشيطها من خلال الستيرويد هرمون البروجستيرون. ويوجد هذا المستقبل في شكلين رئيسيين، المستقبل A(kD94) والمستقبل) B (kD114 في معظم انواع الخلايا، يعمل مستقبل هرمون البروجستيرون A كاداة قامع لعمل البروجستيرون في حين ان وظيفة مستقبل هرمون البروجستيرون B هو منشط لعمل البروجستيرون من نفس الجينات. مستقبلات هرمون البروجستيرون موجودة في الجهاز التناسلي للانثى، الغدد الثدية والدماغ والغدة النخامية ويكون تنشيط المستقبل بواسطة هرمون البروجستيرون. ولمستقبلات هرمون البروجستيرون عند الاناث دور كبير في عملية الاباضة، زرع الاجنة ونمو الغدة الثدية وسير الحملالهدف من الدراسة1 - دراسة التعبير المناعي النسيجي الكيميائي لمستقبلات الاستروجين الفا والبروجستيرون في سرطان الخلايا الانتقالية للمثانة بواسطة التقنية المناعية (التعبير المناعي النسيجي).2 - دراسة العلاقة بين مستقبلات الهرمونات المذكورة مع بعض المتغيرات والخصائص السريرية المرضية المتاحة للحالات المرضية. اجريت هذه الدراسة على 95 عينة من مرضى سرطان الخلايا الانتقالية للمثانة (68 حالة من الذكور و27 حالة من الاناث). درست العينات بواسطة صبغة الهيماتوكسيلين وصبغة الايوسين وذلك لتاكيد التشخيص، درجة التمايز والمرحلة من المرض ودرست العينات بالطريقة المناعية (التعبير المناعي النسيجي الكيميائي) مع مستقبلات الاستروجين الفا والبروجستيرون لمعرفة ما اذا كان هناك علاقة مع بعض المتغيرات المتاحة مثل الجنس والعمر والمرحلة، ودرجة الورم. تم تقسيم المرضى حسب العمر الى اقل من 65 سنة واكبر او يساوي 65 سنة. وكان متوسط عمر جميع الحالات 64.6 وانها تراوحت بين 30سنة الى 90 سنة. الحالات التي تم جمعها من مختبرات الفحص النسيجي في مستشفى الحلة التعليمي، مدينة الامام الحسين الطبية في كربلاء، ومختبر السجاد التخصصي في كربلاء. كانت نتائج العمل تشير الى 15 عينة ايجابية لمستقبلات هرمون الاستروجين الفا، وكانت ست حالات ايجابية لمستقبلات هرمون البروجستيرون. وان من هذه العينات الايجابية من مستقبلات هرمون الاستروجين الفا، 10 عينات من الذكور وخمس عينات من الاناث وان العينات الايجابية الستة من مستقبلات هرمون البروجستيرون جميعها ذكور. بعد دراسة النتائج احصائيا كان هناك ارتباط احصائي بين مستقبلات الهرمونين سويا (ERα / PR) ومرحلة الورم (P ≤ 0.05 ).و لم يكن هناك اي ارتباط احصائي بين العوامل الاخرى بما في ذلك السن والجنس ودرجة التمايز.من النتائج اعلاه يمكن لنا ان نستنتج ان هناك فقط علاقة بين مستقبلات هرمون الاستروجين الفا والبروجسترون معا وبين مرحلة سرطان الخلايا الانتقالية للمثانة ولا يوجد اي علاقة بين هذه المستقبلات واي عامل او متغير اخر ممكن ان يساعد في تقييم هذا النوع من السرطانات | Urinary bladder cancer occurs in all countries around the world. It is the first most common malignancy of the genitourinary tract in Iraq. Urinary bladder cancers present as urothelial bladder carcinoma or as transitional cell carcinoma, which account for about 90%, and the remaining 10% represent squamous cell carcinoma, adenocarcinoma, and other types. Urothelial Bladder cancer is a complex disease that have various internal and external risk factors like age, genetic factor, gender, smoking, exposure to chemical carcinogens and others. There are many tumor markers studied in urothelial bladder cancer (transitional cell carcinoma) like Estrogen and Progesterone receptors, CK20, CK18, CK8, Ki67, Her - 2/ Neu, CA19.9, Glutathione and Glatt Reductase and many others.Estrogen receptors (ER) are members of the superfamily of nuclear hormone receptors they play an important role in growth of estrogen - responsive tumors, including breast and endometrial cancers. There are two different forms of the estrogen receptor, usually referred to as α and β, each encoded by a separate gene (ESR1 and ESR2, respectively).The progesterone receptor (PR) are related to the nuclear receptor superfamily and present in two isoforms, PR - A and PR - B, which arise from different promoter usage in a single gene located on chromosome 11.Aims of study1 - To detect and assess any expression of estrogen and progesterone receptors in urothelial cell carcinoma of urinary bladder by immunohistochemical technique.2 - To study the relationship of receptor expression to some of clinicopathological features available for the present cases like age, sex, grade and stage of tumor.Patients and methodsA retrospective study was conducted on 95 Paraffin embedded blocks (68 cases male and 27 cases female) of urothelial cell carcinoma of urinary bladder specimens (biopsy and TUR). Firstly investigated by Hematoxylin and Eosine stain for histopathological study to confirm the diagnosis, grade and stage (Ta and TII). Then the cases undergo immunohistochemical staining with estrogen and progesterone monoclonal antibody to study if there were expression and correlate the expression to some of clinicopathological features available like sex, age, stage, and grade of the tumor. The age of patient classified as <65 years old and ≥ 65 years old. The cases collected from laboratories of Histopathology of AL Hilla Teaching Hospital, Imam AL Hussien Medical City in Karbala, and ALSajjad private histopathological laboratory in Karbala.ResultsFrom these 95 cases, 15 cases were positive for estrogen receptor, and six cases were positive for progesterone receptor. From these 15 positive cases of estrogen receptor, 10 cases were male and 5 cases were female. Positive low grade were 11 cases and positive high grade were 4 cases. Positive stage 0a were 7 cases and positive stage II were 8 cases. From these 6 positive cases of progesterone receptor, all cases were male. Positive low grade were 5 cases and positive high grade were1. Positive stage Ta were 3 cases and positive stage T II were 3 cases. There was a significant association between combined receptor expression (ERα/PR) and tumor’s stage (Ta and TII), p value ≤ 0.05 is significant. There were no significant association between combined receptors expression and other parameters including age, sex, and grade (p value > 0.05).Conclusions1 - There was no statistically significant association between estrogen α and progesterone receptors expression a lone in UBC and the parameters that we have studied (age, sex, stage (Ta and TII), and grade of tumor). 2 - There was a statistically significant association between combined receptors expression (ERα/PR) and tumor’s stage (Ta and TII) only, p value ≤ 0.05 is significant. There was no significant association between other parameters including age, sex, and grade with the combined hormone receptors expression (p value > 0.05). 4 - According to our finding estrogen α and progesterone receptors expression are not reliable indicators in association to clinicopathological status of UBC. 5 - Our results confirm results obtained by previous studies on the same subject

التعابير المناعية النسيجية الكيميائية لبروتين كي اي - 67 والعامل المحرض من نقص الاكسده - 1الفا في سرطان الثدي ثلاثي السلبية == Immunohistochemical Expression of Ki - 67 and Hypoxia - Inducible Factor - 1? in Triple Negative Breast Cancer

Author name: مهدي جاسم محمد علي
Supervisor name: حيدرعبد الرضا الخفاجي | عباس فاضل حسون
General topic: Medicine
Specific topic: Diseases
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: ان سرطان الثدي يمثل النوع الاكثر شيوعا من سرطان النساء في جميع انحاء العالم وله عبئا كبيرا على سلطات الصحة العالمية. ان احد اهم الانواع الجزيئية لسرطان الثدي هو سرطان الثدي ثلاثي السلبيه الذي يتميز بلتعبير السلبي لمستقبلات هرمون الاستروجين وهرمون البروجسترون وعامل النمو البشاروي وهو غير متجانس سريريا او من ناحية اخرى هو في الغالب من النوع الشرس والقاتل. هناك مؤشرات متزايدة لدعم دراسة المناعة النسيجية الكيميائية لمختلف المعلمات وتكون بطريقة او باخرى متعلقة بالمعرفة المتزايدة حول التشخيص والعلاج وتحديد سرطان الثدي او لاضافة نتائج جيدة. ان احد هذه المعلمات التي تعتبر من العوامل المحدد والمرتبطة بمعدل انتشار سرطان الثدي الثلاثي السلبية هوبروتين كي اي - ٦٧و العامل المحرض من نقص الاكسده - ١الفا. الاهداف : هدف هذه الدراسة هو العرفة على اي شراكة بين سرطان الثدي ثلاثي السلبيه وغيره من الانواع الفرعية لسرطان الثدي اواي ارتباط بينه وبين التعابير المفرطة لبروتين كي اي - ٦٧ والعامل المحرض على نقص الاكسده - ١الفا مع العديد من المتغيرات السريرية والمرضية .المواد وطرق العمل : هذه الدراسة شاملة ومستعرضة لمختلف القطاعات والفئات اجريت في قسم علم الامراض في كلية الطب - جامعة بابل تضمنت ٢٨١ امراءة ممن يعانون من سرطان الثدي الابتدائي اختيروا من البيانات التي تم الحصول عليها من المحفوظات في مختبرات مستشفى الحلة التعليمي ومستشفى الصدر التعليمي في النجف ومدينة الحسين الطبية ومختبر السجاد الخاص في كربلاء خلال الفترة من نوفمبر ٢٠١٣ الى ابريل ٢٠١٥. كما ان المرضى صنفوا استنادا الى الصبغه المناعية النسيجية الكيميائية الى مجموعتين ٥٤حاله من سرطان الثدي ثلاثي السلبية و٢٢٧حاله من الانواع الفرعية الاخرى.الانواع النسيجية والدرجة قسمت وفقا لتصنيف منظمة الصحة العالمية ودرجة بلوم - ريتشاردسون المعدلة. المتغيرات السريرية والمرضية والتي تضم العمر وحالة انقطاع الطمث وحجم وجهة الورم ونوع الجراحة وعودة الورم ونظام TNM للتدريج والدرجة. تم التعبير عن بروتين كي اي - ٦٧ والعامل المحرض من نقص الاكسده - ١الفا عند صبغه مع نظام الكشف عن الصبغه المناعية لمعقد افيدين بيوتين على ٥٤ عينة من الانسجة المحفوظة بالفورمالين والمطمورة بشمع البارافين من حالات سرطان الثدي ثلاثي السلبية. وقد تم تحليل العلاقة بين جميع متغيرات الدراسة بطريقة اختبار مربع كاي. وتعتبرالنتائج ذات دلالة احصائية اذا كانت قيمة ٠٬٠٠٥P ≤.النتائج : لقد تراوحت اعمار المرضى بين٢٣ - ٨٥ سنة , (متوسط ٥١٬٢٣± ١١٬٢٦) سنة. سرطان الثدي ثلاثي السلبية يشغل ١٩٬٢٪ فقط من مجمل الحالات وغالبا ما تكون المصابات به اصغر عمرا من غيره من الانواع الفرعية لسرطان الثدي. نسيجيا كان سرطان الاقنية الاختراقي غير المحدد الاكثر شيوعا من المجموع الكلي لحالات ) ٢٢٣/٢٨١ (.التقييم المناعي النسيجي الكيميائي لبروتين كي اي - ٦٧يرتبط بقوة مع حجم الورم(٠٬٠٢٨=P) ودرجة الورم(٠٬٠٠١ P<) وانتشارالعقدة الليمفاوية (٠٬٠٢=P) والنقائل السرطانية مكان بعيد (٠٬٠٠١ P<). في حين التقيم لبروتين العامل المحرض من نقص الاكسده - ١الفا يرتبط بقوة مع درجة الورم (٠٬٠٠١=P) وانتشار العقدة الليمفاوية (٠٬٠٠١ P<) ولتعبير بروتين كي اي - ٦٧ (٠٬٠٠٣=P).الاستنتاجات : من هذه النتائج يمكن الاستنتاج بان لتعبير بروتين كي اي - ٦٧ والعامل المحرض من نقص الاكسده - ١الفا دور هام في نشوء المرضية لسرطان الثدي ثلاثي السلبية. هذا ويمكن ان يؤيد مقترح دورهما في المقاومة للادوية، والى زيادة او الانتشار غير المنضبط للخلايا الخبيثة. حتى انه قد يكونا موصلان هامين في التنبا الاسوا للمرضى الذين يعانون سرطان الثدي ثلاثي السلبية. | Breast cancer represents the most frequent type of women cancer worldwide and it has a huge burden on the global health authorities. One of the most important molecular subtypes of breast cancer is the triple negative - breast cancer (TNBC), which is characterized by absent expression of estrogen(ER), progesterone(PR) and human epidermal growth factor - 2 receptors (HER - 2). There are mounting indications to support the study of different markers immunohistochemically(IHC) in one way or another and they related to an increased knowledge about diagnosis, treatment and prognosis of breast cancer or to adding good outcome. One of these markers regarded as a prognostic factor and closely related to the proliferation rate in triple negative - breast cancer is Kiel - 67(Ki - 67) or hypoxia inducible factor - 1 (HIF - 1α).Objectives : The aim of study is to find out that if there is any association between the triple negative breast cancer and other breast cancer subtypes or any association between it and over expression of Ki - 67 and HIF - 1α and several clinicopathological variables. Materials and methods : The cross - sectional study was conducted in the Department of Pathology in the College of Medicine - Babylon University in which 281 female patients with primary breast cancer were selected from Data obtained from archives in the laboratories in AL - Hilla Teaching Hospital, AL - Sadr Teaching Hospital in Najaf and AL - Hussein Medical City and Al - Sajad Private laboratory in Karbala during the period from November 2013 to April 2015. The patients were classified based on their immunohistochemical staining into two groups as 54 cases of triple negative breast cancer and 227 cases of other subtypes. The Clinicopathological variables comprising age, menopausal status, tumor size and site, type of surgery, recurrence, TNM Staging system, histological subtype and grade were estimated. The expression of Ki - 67 and HIF - 1α were stained with Avidin - Biotin Complex detection system of Immunostaining on 54 selected formalin fixed, paraffin embedded tissues of Triple negative breast cancer cases. The relationship between all study variables were analyzed by chi - square test. The results were considered statistically significant if the p value was ≤ 0.05. Results : The overall patients ages ranged from 23 - 85 years (mean 51.23±11.26) years old.Triple negative breast cancer presented in only 19.2% of overall cases; most frequently younger age than other breast cancer subtype. Histologically, Infiltrative ducal carcinoma was the most frequent type (223/281). Immunohistochemically, Ki - 67 expression is strongly associated with tumor size (p=0.028), grade (p<0.001), lymph node metastasis (p=0.02) and distant metastasis (p<0.001). While HIF - 1α expression is strongly associated with grade (p=0.001), lymph node metastasis (p<0.001) and Ki - 67 expression (p=0.003). Conclusions : From these results, it can be concluded that Ki - 67 and HIF - 1α expression have an important role in pathogenesis of triple negative breast cancer evolution. This may support the suggestion of their role in drug resistance, and in increased or uncontrolled proliferation of the malignant cells. So they may be an important conductor of the worst prognosis in triple negative - breast cancer patients

تقييم الجوانب البدنية والنفسية الاجتماعية لاطفال عمر المدرسة المصابين بمرض فقر دم البحر الابيض المتوسط الشديد في النجف الاشرف == Assessment of Physical and Psychosocial Aspects of School Age Children with Thalassemia Major in Al Najaf Al Ashraf

Author name: عمار عبد الاله عبد الكاظم
Supervisor name: قحطان هادي حسين | سلمى كاظم جهاد
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: اجريت دراسة وصفية في النجف الاشرف للفترة في الثاني من ايلول 2014 ولغاية الثالث من اب 2015, لتقييم الجوانب البدنية والنفسية الاجتماعية لاطفال عمر المدرسة المصابين بمرض فقردم البحر الابيض المتوسط الشديد, ولتحديد العلاقة بين الجوانب البدنية والنفسية الاجتماعية مع المتغيرات الشخصية والصفات السريرية لهم. عينة غير احتمالية (غرضية) شملت (100) مريض لكلا الجنسين مع ابائهم من اطفال عمر المدرسة المصابين بالمرض في النجف الاشرف كانوا مشخصين طبيا ومراجعين الى مركز الثلاسيميا في مستشفى الزهراء التعليمي للولادة والاطفال . تم جمع البيانات من خلال تنظيم استمارة الاستبيان المطورة (النسخة العربية) وكذلك بواسطة المقابلة الشخصية مع كل طفل ووالده او والدته الذي تم شمولهم في الدراسة الحالية. النسخة النهائية لاستمارة الاستبيان تكونت من ثلاثة اجزاء : الجزء الاول تكون من استمارة البيانات الشخصية, الجزء الثاني تكون من استمارة الصفات السريريه.,والجزء الثالث تكون من اربع جوانب : الجانب البدني,الجانب النفسي, الجانب الاجتماعي,والجانب المدرسي.عن طريق تقنية المقابلة المباشرة مع اطفال الثلاسيميا وابائهم. تم تحقيق ثبات استمارة الاستبانة من خلال اجراء الدراسة المصغرة وحددت مصداقيتها من خلال مجموعة مكونة من (17) خبير. وتم وصف وتحليل البيانات باستخدام اساليب الاحصاء الوصفي والاستنباطي. اظهرت نتائج الدراسة الحالية ان التقييم النهائي لعينة البحث, الجوانب البدنية والنفسية والاجتماعية والمدرسية كانت متاثرة بسبب الثلاسيميا الكبرى وان الجانب العاطفي كان اكثر جانب متاثر متبوع بالجانب الاجتماعي والبدني والجانب المدرسي. اوجدت الدراسة ان هنالك تاثير من حيث الجنس وعدد مرات نقل الدم في الشهر على الجانب البدني كما ان العمر والجنس ومستوى الطفل في المدارس الابتدائية والوضع الاجتماعي الاقتصادي ومدة حدوث المرض يؤثر على الجوانب النفسية الاجتماعية للاطفال المصابين بالثلاسيميا الكبرى. اوصت الدراسة بوجود طبيب نفساني واجتماعي في مركز الثلاسيميا للمساعدة في تحسين الصلة بين الاطفال، والمدارس، والاسر، والاطباء. وسائل الاعلام الجماهيري الموجه للصحة في توفير المعلومات للسكان حول الثلاسميا وغيرها من الامراض الموروثة | A descriptive design was carried out in Al Najaf Al Ashraf from September 2nd, 2014 to August 3rd 2015, in order to assess physical and psychosocial (emotional, social, and school) aspects of school age children with thalassemia major, and find out the relationship between physical and psychosocial aspects for those children with socio - demographic characteristics and clinical data. A Non Probability "purposive" sample of (100) school age children with thalassemia major, who were medically diagnosis and attended the thalassemia center of Al - Zahra Maternal and child Teaching Hospital.Data was collected through the utilization of a developed questionnaire (Arabic version) and by means of interview method with each child and their parents who is included in the present study. The final copy of the questionnaire consists of three parts, the 1st part consists of socio demographic data; 2nd part consists of clinical characteristics, and the 3rd part consists of four domains : physical, emotional, social, and school domain, by means of direct interview technique with thalassemia children and their parents.Reliability of the questionnaire is determined through a pilot study and the validity through (17) experts. The data analyzed through the use of the descriptive and inferential statistical analysis procedures.The findings of the present study indicated that the overall assessment for the study sample physical, emotional, social, and school aspects were affected due to thalassemia major and the emotional domain had highly affected domain, followed by the social, and the physical and school domain.The study concludes that the gender and number of blood transfusion per month were affecting the physical aspect of the study sample due to thalassemia major. The age, gender, child primary school levels, Socio - economic status and their duration of disease occurrence were affect the psychosocial aspects of the study sample due to thalassemia major. The study recommends that a psychologist and sociologist in the hematological units is a necessary present to help in promotion a relationship between children, school representatives, the families, and the doctors. Mass media should have awareness in providing information to population about thalassemia and other inherited diseases.

تقييم وتعريف المكورات المسبحية الطافرة والمتحولة اللثوية في مرضى تسوس الاسنان وامراض النسيج الداعم للاسنان == Evaluation and Identification of Streptococcus mutans and Entamoeba gingivalis in Patients with Periodontal Diseases and Dental Caries

Author name: مؤيد نعمة مصلح الخفاجي
Supervisor name: الهام عباس بنيان الساعدي | هيام خالص المسعودي
General topic: Medicine
Specific topic: Microbiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: The present was carried out during the period of November 2014 to April 2015 in Al - Hilla City. This study included 100 samples which were collected from patients at ages ranged between 4 to 75 years old whom were suffering from dental caries and periodontal diseases ; (50) samples were taken from patients infected with dental caries (23 male and 27 female) and (50) samples taken from patients with periodontal diseases (15 male and 35 female), who have submitted to a college of Dentistry in Babylon university and special center of Dentistry. Thirty samples were taken from apparently healthy persons and considered as control.The isolation and identification of S. mutans was performed by Mitis Salivarius Bacitracin agar as a selective medium and biochemical tests as well as API 20 strep, then investigated the virulence factors and show the effect of some antibiotics on bacterial isolates, and the identification of E. gingivalis parasite was by a wet preparation method.The obtained results showed that S. mutans was with a higher existence in patients with dental caries, with lower existence in the patients with periodontal diseases and it was found in healthy persons (30%, 18%, and 0%) respectively. Entamoeba gingivalis was higher in patients with periodontal diseases than patient with dental caries and less in healthy individuals (62%, 24%, and 6%) respectively. The presence of these microorganisms was related to the type of dental disease (p=0. 009), gender (p=0. 009), age (p=0. 008) and risk factors (diabetes, smoking and hypertension) (p=0.037).The effect of some antibiotics on S.mutans was also tested, and the obtained results showed that all isolates were with high resistance to Erythromycin (70.8%) and (66.7%) were resistant to Doxycycline. Some isolates showed low level of resistance to Vancomycin (54.2%), CefatoximeII(33.4%) and Clindamycin (25%), while these isolates were with high susceptibility to Chloramphenicol (100%) and Ofloxacin (83.4%).Finally, some virulence factors of S. mutans were studied and it was seen that the (62.5%) of S. mutans isolates produced α - hemolysis and (8.3%) produced β - hemolysis but (29.2%) of isolates non - hemolysis, but (58.3%) of isolates were made capsule and (100 %) were able to synthesize glucan, (83.3%) of S. mutans isolates were able to produce mutacin and (45.83%) of isolates were found to produce dextranase enzyme, while (84%) were able to biofilm formation .In addition, all isolates in this study were able to adhere to oral epithelial cells.

دراسة على المايكرومايكروبية الشائعة المعزوله من القناة الهضمية وبعض المعايير المناعية للمرضى الذين يعانون من مرض السكري النوع الثاني == A Study on Common Microbiaes isolated from Gastrointestinal and some Immunological Parameter in Patients with Type II Diabeties Mellitus

Author name: شذى خزعل كاظم الوائلي
Supervisor name: هيام خالص المسعودي | علي حسين البياتي
General topic: Medicine
Specific topic: Microbiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: المرضى الذين يعانون من من داء السكري النوع الثاني هم مجموعة غير متجانسة من الاضطرابات التي تتميز بمقاومة الانسولين الواسعة للانسجة ويختلف على نطاق واسع. داء السكري من النوع الثاني هي حتى الان الاكثر شيوعا. تضمنت الدراسة (100) مريض مصاب بالسكري النوع الثاني مشخص من قبل اطباء متخصصين بالسكري و(50) شخص من الناس الاصحاء وفي الفئه العمرية (25 - 65) سنة الوافدين الى مستشفيات في بابل (القاسم ومرجان) خلال الفترة من كانون الثاني 2015 حتى حزيران 2015.واظهرت النتائج ان البكتريا السالبه لصبغة كرام من مجموع العزلات هي السائدة مقارنة مع البكتريا الموجبه لصبغة كرام تشكل 26٪ وشكلت العزلات البكتيرية E.coli الاكثر شيوعا كانت يتبعها Enterobacter spp., K.Pneumoniae, Proteus spp., والبكتريا الاقل شيوعا كانتS.aureus, S.epidermidis, Citrobacter, Micrococcus Kocuria kristinae وStreptococcus spp,في حين ان الطفيليات الاكثر شيوعا كانت E.histolyticaبنسبة 55% وGiardia lambliaبنسبة 45% . تم دراسة عوامل الضراوة للبكتريا الشائعه المعزولة من مرضى السكري من النوع الثاني في هذه الدراسة. وكانت عزلات K.pneumoniae وعزلات Enterobacter وبعض عزلات E.coli تعطي الكبسول بينما بكتيريا Proteus spp. المعزوله في هذه الدراسة لم تمتلك الكبسولة. تم الكشف عن عامل الاستعمار CF - I وIII في العزلات البكتيرية فكانت ايجابيه في البكتريا الاكثر شيوعا وكانت جميع عزلات بكتيريا المكورات العنقودية الذهبية قادرة على انتاج المخثرة التي يعتبر عامل الضراوه لامراضية هذه البكتيريا. وان كل عزلات المكورات العنقودية الذهبية والاشريكية القولونية اظهرت تحللا كاملا (lyses كاملة) β - الانحلالي، في حين ان جميع عزلات المكورات العقدية نمط (lyses غير مكتملة) α - الانحلالي حيث اظهرت خط مخضر حول المستعمرات البكتيرية. وكانت جميع عزلات S.epidermidis وبعض العزلات من Proteus spp. (غير الحالة للدم) γ - الحالة للدم. في هذه الدراسة تم التحري عن sidrophore بين العزلات البكتيرية واظهرت النتائج ان جميع العزلات البكتيرية (E. coli K.Pneumoniae,)، ومعظمها من عزلات E. aerogenes و.Proteus spp كانوا قادرين على صنع sidrophore. وكانت بعض العزلات من. Proteus spp وEnterobacter ايجابية لتفاعل الجيلاتيناز، في حين ان جميع العزلات من Klebseilla واكثر عزلات E.coli سالبة لهذا العامل. واظهرت نتائج اختبار انتاج ال lipase في سالبة الجرام ان معظم العزلات ايجابية لاختبار lipase. وكشفت النتائج ان جميع العزلات كانت موجبه Biofilm وضع تشكيل (50٪)، في حين لا يوجد عزلات سالبه له. وفيما يتعلق بعوامل الضراوة الشائعة للبكتيريا المعزولة من عدم وجود مرض السكري وعوامل الضراوة فكانت نادرة. وكانت نتائج المتغيرات المناعية (C3، C4، Ig A، IL4، وIL6) للمرضى السكري في الدراسة, قد انخفضت مستويات C3، IgA، IL4، وIL6 للمرضى السكري ، في حين مستوى C4 قد ارتفع. من خلال نتائج هذه الدراسة، يمكن ان نستنتج؛ ان انواع البكتيريا التي عزلت من مرض السكري من النوع الثاني هي التالية E.coli تليها K. Pneumoniae, Enterobacter spp., Proteus spp, Micrococcus, Citrobacter S.epidermidis, kocuria kristinae, S.aureus , and Streptococcus spp. والطفيليات هي الاميبا الحاله للنسيج ثم الجيارديا اللامبيليا | In this study include (100) diabetic type (II) patients as diagnosed by Diabetolegist and 50 healthy control with an age range of (25 - 65 years) who attended to the two hospitals in Babylon : (Al - Qasem and Marjan), during the period from January 2015 until June 2015. Shown that grams - negative bacteria constitutes 74% from the total isolates and were considered the predominant aetiological agent of DM compared to gram - positive bacteria which constitutes 26%. The most common bacterial isolates were E.coli followed by Klebsella Pneumoniae, Enterobacter spp, Proteus spp, and less common bacteria were Staphylococcus aureus, Staphylococcus epidermidis, Kocuria kristinae, Citrobacter, Micrococcus and Streptococcus spp, whereas the most common parasites were Entamoeba histolytica 55% and Giardia lamblia 45%.The virulence factors of common bacterial isolated from diabetes Mellitus type II in this study are studied. The capsule was present in all Klebsella pneumoniae isolates, Enterobacter isolates and some isolates of E.coli, whereas the other bacteria such as Proteus mirabilis isolates in this study does not possess the capsule. Colonization factor antigens were detected; The CF - I and III were detected in mostly bacterial isolates which showed positive results with these factors. All isolates of Staphylococcus aureus bacteria were able to produce coagulase which is considered as a virulence factor for pathogenicity of these bacteria. All isolates of Staphylococcus aureus and E. coli expressed β - hemolytic (complete lyses), while all isolates of Streptococcus were α - hemolytic pattern (incomplete lyses) showing a greenish line around the bacterial colonies. All isolates of Staphylococcus epidermidis and some isolates of Proteus spp. were γ - hemolytic (non hemolytic). In the present study the siderophore synthesis was investigated among bacterial isolates and the results showed that all bacterial isolates (E. coli and K. pneumonia), and mostly of isolates of Enterobacter spp. and Proteus spp. were able to synthesis siderophore. Some isolates of Proteus mirabilis and Enterobacter spp. were positive for gelatinase reaction, while all isolates of Klebseilla pneumoniae and mostely E.coli were negative for this factor. The results of lipase production test in G - ve showed that most isolates were positive to lipase production test. The results revealed that all isolates were biofilm former, high and moderate biofilm formation mode were account for (50%) while there is no isolates that express non - biofilm formation. Regarding the virulence factors of common bacterial isolated of non - diabetes Mellitus have rare virulence factors.The results of Immunological parameters (C3, C4, IgA, IL4, and IL6) for DM patients were studied. In this study the levels of C3, IgA, IL4, and IL6 for DM patients were decreased, whereas the level of C4 was increased. In light of the results documented in this study, we can conclude the following; the types of bacteria which isolated from diabetes mellitus type II from the most to least common are E.coli followed by K. Pneumoniae, Enterobacter spp., Proteus spp., S.aureus, S.epidermidis, kocuria kristinae, Citrobacter, Micrococcus, and Streptococcus spp. And parasite : Entamoeba histolytica and Giardia lamblia isolated from diabetes mellitus type II. Most bacterial isolates in this study have the ability to possess more than one virulence factor such as capsule, siderophors, lipase production, hemolysin, extracellular protease, adherence factors, and biofilms to produce infection in diabetes mellitus type II patients. The virulence factors of common bacterial isolated in non - diabetes mellitus have rare virulence factor. The levels of Immunological parameters of C3, IgA, IL4, and IL6 for DM patients were decreased, whereas the level of C4 was increased.

تقييم رضا النساء الحوامل نحو خدمات الرعاية الصحية الاولية المقدمة فـــي مراكـــــز الرعاية الصحية الاولية في مدينة الحلة == Assessment of Pregnant Women Satisfaction with Primary Health Care Services Provided at Primary Health Care Centers in Al - Hilla City

Author name: علي فارس عبد الحسين السعدي
Supervisor name: امين عجيل ياسر الياسري
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: اجريت دراسة وصفية تحليلية في مراكز الرعاية الصحية الاولية للفترة ما بين 1 كانون الاول 2014 الــى10 ايار 2015 من اجل تقييم رضا النساء الحوامل نحو خدمات الرعاية قبل الولادة المقدمة في مراكز الرعاية الصحية الاولية في مدينة الحلة. اختيرت عينة غير احتمالية (عينة غرضية) كان قوامها (220) امراة حامل. جمعت البيانات من خلال استخدام استبانة لتقييم الخدمات الرعاية قبل الولادة والرضا عنها. تكونت اداة الدراسة من اربعة اجزاء والتي تتكون من اولا : المعلومات الشخصية تشمل السكن، العمر، المستوى التعليمي، المهنة والدخل الشهري. ثانيا : معلومات التاريخ الصحي للحامل تشمل عدد مرات الحمل السابقة، مدة الحمل الحالي, عدد الاجهاضات, مضاعفات الحمل, التوعية الصحية وزيارات خلال فترة الحمل, ثالثا : معايير الخدمات قبل الولادة يتكون من (35) فقرة, رابعا : معاير رضا النساء الحوامل ازاء الخدمات قبل الولادة لهم في وحدة رعاية الام والطفل يتكون من (30) فقرة. حدد الثبات والمصداقية من خلال اختبار الثبات والمصداقية التي تحققت من خلال لجنة مكونة من (13) خبير. تم اجراء تحليل البيانات باستخدام برنامج SPSS)) وانجزت عملية تحليل البيانات من خلال استخدام طرائق اسلوب التحليل الاحصائي الوصفي (النسب المئوية، التكرارات، شريط الرسم البياني, الوسط الحسابي ومقياس التكافؤ النسبي (Relative Sufficiency) واختبارات مربع كاي ((Chi - Square tests. النتائج والاستنتاجات من هذه الدراسة تشير الى ان هناك تقييم شامل لخدمات الرعاية قبل الولادة لوحدة صحة الام والطفل كان متوسط المستوى وان رضا النساء الحوامل من خدمات الرعاية السابقة للولادة جيدة المستوى في مراكز الرعاية الصحية الاولية في مدينة الحلة. اوصت الدراسة بضرورة انشاء مراكز صحية جديدة لتقليل الزخم الحاصل على المراكز الصحية وفقا لاعداد النساء الحوامل خلال الموقع الجغرافي للمنطقة. والتركيز على وجود مساحة كافية في بقية مراكز الرعاية الصحية الاولية. وقد تبنت منظمة الصحة العالمية نموذج جديد للرعاية السابقة للولادة في خدمات رعاية الامومة لدينا للقضاء على الحواجز التي تعيق الحوامل من الحضور المنتظم لزيارة الرعاية السابقة للولادة ، ومع القيام بالكشف المبكر عن مضاعفات الحمل بالاضافة الى تعزيز الرعاية الصحية لهم في مجتمعنا | A descriptive design and analytical study was conducted in primary health centers for the period between 1th December 2014 to 10th May 2015 in order to assess pregnant women satisfaction with primary health care services provided at primary health care centers in Al - Hilla City. A Non - Probability (purposive) sample of 220 cases selected from pregnant women in two primary health care sectors including (22) primary health care centers that provide daily antenatal care services. Data were collected through the use of a questionnaire for assessing antenatal care services and pregnant women satisfaction. The questionnaire is comprised of four parts which include : Part - I is concerned with demographic data including age group, residence, occupation, level of education, monthly income, part - II - maternal health history, including gravida, duration of pregnancy, abortion, complications, services provider and type of visits, part - III antenatal care services domain which consists of (35) items, and part - IV pregnant women's satisfaction domain which consists of (30) items. Reliability of the questionnaire is determined through a pilot study and validity is achieved through a panel of (13) experts. Data are analyzed through using the Statistical Package of Social Sciences (SPSS, Version 20) performed through the use of descriptive statistical data analysis approach.The findings and conclusion of the study indicate that there is overall evaluation of the ANC services for MCH unit is fair, the ANC services including family planning, health education and postnatal services need improvement. The ANC services provided in PHC centers were curative for all pregnant women with different of their demographic characteristics and overall pregnant women satisfactions is good in respect to antenatal care services at the primary health care centers in Al - Hillah City.The study recommends the establishment of buildings for primary health care centers according to the numbers of pregnant women within their geographical areas and emphasis on having enough space in the rest of primary health care centers. Adoptions of the new WHO antenatal care model in maternal care services to eradicate women’s barrier to attending regularly for antenatal care visits, and reveal early detection of pregnant women complications and promoting help in maternal health care in our society.

تقييم الاكتئاب والقلق بين مرضى السرطان في مدينة بابل == Assessing Depression and Anxiety among Cancer Patients in Babylon City

Author name: برهان هادي درب السلطاني
Supervisor name: انتصار عبد الغني الخضري
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: دراسة وصفية تحليلية اجريت للفترة ما بين 5 تشرين الثاني 2014 الى 9 نيسان 2015 من اجل تقييم الاكتئاب والقلق بين مرضى السرطان في مدينة بابل. عينة غير احتمالية (غرضية) ل (100) مريض اختيروا من مركز بابل لمعالجة السرطان / مدينة مرجان الطبية، مركز بابل لمعالجة السرطان يجهز تدابير علاجية يومية لمختلف انواع السرطان. قد جمعت المعلومات من خلال استخدام استبانة لتقييم القلق والاكتئاب. تكونت اداة الدراسة من ثلاثة اجزاء احتوت على (71) فقرة. والتي الجزء الاول : احتوت على المعلومات الشخصية وتشملت العمر، الجنس، الحالة الزوجية، المستوى التعليمي، السكن، العمل ونوع العمل والصفات السريرية تشملت نوع السرطان، مراحل السرطان ونوع العلاج. الجزء الثاني تكون من مقياس القلق الذي احتوى على (50) عبارة. الجزء الثالث تكون من مقياس الاكتئاب الذي احتوى على (21) عبارة. الثبات حدد من خلال اختبار معامل الارتباط الفا كرون باخ وحددت المصداقية من خلال عرض الاستبانة على مجموعه من الخبراء (16) خبير. تم تحليل البيانات باستخدام برنامج الاحصائي SPSS)) من خلال استخدام طريقة التحليل الوصفي (النسب المئوية، التكرارات، متوسط القيم، والانحراف المعياري والاحصاء الاستدلالي بطريقة اختبارات مربع كاي. اشارت نتائج الدراسة بان اغلب مرضى السرطان يعانون من مستوى عالي من القلق والاكتئاب. اغلب عينة مرضى السرطان من فئة عمرية (46 - 60) سنة، اناث، متزوجين، غير متعلمين، يسكنون المناطق الحضرية وربات البيوت، مصابين بسرطان الثدي، خلال المرحلة الثانية من السرطان (المرحلة العضوية) واعلى نسبة للعلاج هو العلاج الكيمياوي والجراحي من حيث النوع. اظهرت نتائج الدراسة ان هناك علاقة بين المرضى الاميين، ربات البيوت، المرضى من الموظفين الحكوميين والمرضى الذين خاضعين العلاج الجراحي والكيمياوي مع مستوى القلق الحاد وكذلك مع الاكتئاب الحاد. اوصى الباحث الى تحسين الرعاية وتوفير الدعم النفسي والعاطفي لمرضى السرطان وخصوصا بواسطة الكادر التمريضي، التنسيق بين مركز معالجة الاورام وقسم طب الصحة النفسية لغرض اعطاء العلاج لتقليل القلق والاكتئاب، تثقيف المؤسسات الحكومية لغرض لكشف المبكر عن السرطان وكذلك اجراء دراسات مماثلة على الصعيد الوطني لتقييم القلق والاكتئاب بين مرضى السرطان. | A descriptive analytical study is conducted from 5th November 2014 to 9th April 2015 to assess depression and anxiety among cancer patients in Babylon city. A non - probability (purposive) sample of 100 patient selected from cancer patients in Merjan Medical City, Babylon Oncology Center that provides daily management for different types of cancer. Data was collected through the use of a questionnaire for assessing depression and anxiety. The questionnaire is comprised of three parts, and containing (71) items. part one is consisted Sociodemographic factors include age, gender, marital status, level of education, residence, occupation ,occupation type and clinical characteristics include cancer type, treatment type and cancer stages, part two is the anxiety scale consists of 50 items, and part three is the depression scale consists of 21 items. Reliability is determined using Alfa correlation (Cronbach's Alfa) and the validity is achieved through a panel of (16) experts. Data is analyzed through using the Statistical Package of Social Sciences (SPSS, Version 20) performed through the use of descriptive statistical data analysis approach, such as frequencies, percentages, mean of scores and inferential statistical approach which is presented as analysis of variance chi - square test. The findings of the study indicate that most cancer patients have severe level of anxiety and depression. Most of the sample cancer patients were (46 - 60) age group, females, married, illiterate, lived in urban areas, housewives, diagnosed with breast cancer. Most of them in organic stage and treated with surgical and chemotherapy treatment .It was found that illiterate patients, housewives, government employees, and surgical and chemotherapy treated patients have significantly severe anxiety level. Cancer patients complaining from severe depression level, especially illiterate patients, patients live in rural areas, housewives, government employee and surgical and chemotherapy treatment. The study recommend improving psychological and emotional status for cancer patients of all types, especially by nursing staff after taking chemotherapy treatment. Coordination between oncology center and the Department of Psychiatry in the hospital for giving treatment to reduce anxiety and depression levels. Educate all government institutions to conduct periodic tests for early detection of cancer, especially breast cancer to reduce spread. Conducting similar studies at the national level to assess anxiety and depression among cancer patients.

تعزيز ممارسات العناية الذاتية لمرضى الصرع ببرنامج تعليمي في مركز الفرات الاوسط للعلوم العصبية في مدينة النجف == Enhancing Self - care Practices for Epileptic Patients by Educational Program at Middle Euphrates Neuroscience Center in AL - Najaf City

Author name: حيـــــــدر ابراهيــــــــم علـــــــي
Supervisor name: سحر ادهم علي
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: لمعرفة تاثير البرنامج التعليمي في تعزيز ممارسات العناية الذاتيه للمرضى المصابين بالصرع من المرضى المراجعين للعيادة الاستشارية في مركز الفرات الاوسط للعلوم العصبيه في مدينة النجف من الفترة ما بين 3 كانون الاول 2014 ولغاية 26 ايار2015. اعتمد مركزا واحدا كمحيط لجمع بيانات الدراسة، العينة قسمت الى مجموعتين وتم تعريضهم الى اختبار قبلي وبعدي، وتطبيق اسلوب البحوث شبه التجريبية. اختيرت عينة من (57) مريض مصاب بالصرع تتراوح اعمارهم ما بين (18 - 47) سنة، مقسمين الى مجموعة ضابطة وعددهم (30) مريض لم يتعرضوا الى اي برنامج تعليمي لتعزيز الممارسات الذاتية حيال المرض، حيث كانوا قد حصلوا على الاستشارة والعناية الروتينية المقدمة في الاستشارية خلال الزيارة. ومجموعة للدراسة وعددهم (27) مريض حضروا ثلاثة جلسات من البرنامج التعليمي الخاص لتعزيز ممارسات العناية الذاتية. صممت استمارة الاستبانة لتقييم ممارسات العناية الذاتية للمرضى المصابين بالصرع وتتكون من جزئين : الجزء الاول، البيانات الديموغرافيا، والجزء الثاني مقسم الى ثلاثة جوانب : الاول، ممارسات العناية الذاتية في (البيت، المطبخ، الحمام، وفي مكان العمل او الدراسة، واثناء النوم)، ثانيا، تعزيز ممارسات العناية الذاتية فيما يتعلق باستخدام الادوية، والجزء الثالث يتضمن ممارسات العناية الذاتية فيما يتعلق بالعوامل النفسية الاجتماعية التي تثير نوبة الصرع.فيما يتعلق بمصداقية الاستمارة تم تقيم وتحديد المحتوى خلال الدراسة الارشادية التي اجريت في الفترة من 3 الى 31 كانون الاول 2014، اما مصداقية محتوى الاستمارة فقد حدد بعد توزيع الاستمارة على (16) خبير حيث اخذ بنظر الاعتبار كل مقترحاتهم، تم جمع البيانات بمقابلة المرضى.النتائج في الاختبار البعدي اظهر اختلاف كبير في ممارسات العناية الذاتية بين اعضاء المجموعة الضابطة عند مقارنتهم بالاختبار البعدي لمجموعة الدراسة.التوصيات : بناء برنامج تعليمي لتزويد مرضى الصرع بمعلومات خاصة وتثقيفهم حول ممارسات العناية الذاتية للسيطرة او تقليل نوبات الصرع. بالاضافة الى وضع خطة لتزويد المرضى بهوية تعريفية للمحافظة وجدولة المتابعة لحالة المريض الصحية بهدف تغطية احتياجات وحل المشاكل التي تواجه المرضى. | In order to determine the effectiveness of the educational program to enhance self - care practices for epileptic patients who visit the clinic in the Middle Euphrates Neuroscience in AL - Najaf City , from the period 21 December 2014 to 26 March 2015. Single center was used as a setting for collecting data, two groups, pre - test and post - test quasi - experimental study design conducted A convenience purposive sample of (57) patients who diagnosed with epilepsy aged from (18 - 70) years was divided into : (n=30) act as control group who did not receive self - care practices educational program and who received a routine care in the clinic during visit. The study group (n=27) who attended three sessions of self - care practices educational program. Questionnaire which was constructed to assess self - care practices for epileptic patients, contained of two parts : First ,demographical data, and second part divided for three aspects : First, self - care practices at (home, kitchen, , bathroom, and work or study place and sleeping ), second : self - care practices related to medication consumption, and the third aspect includes self - care practices related to psychosocial factors that trigger the seizure.To test the content validity of the pre - test form distributed among (16) experts, and according to their notes and suggestion the final form was constructed. In addition to that the reliability was (0.76) investigated through a pilot study by applying coefficient of correlation and interrate reliability. Mean and stander deviation were used to determine the findings, t - test was used in statistical analysis methods in results of current study. The results in post - test show highly significant differences in self - care practice among study group members when compared with the post - test of the control group.The researcher recommended that the epileptic patients should provide with specific information and education about self - care practices to control or decrease seizure attacks. Identification cards policy should be planed to maintain scheduled follow - up to ensure the patients progress in order to cover the needs and solve problems.

تقييم رضا المرضى من حيث العناية التمريضية المقدمة لهم في المستشفيات العامة في مدينة النجف الاشرف == Assessment of Patients' Satisfaction Regarding Nursing Care Provided at General Hospitals in Al - Najaf Al - Ashraf City

Author name: رياض عواد عبد الحسين الزيادي
Supervisor name: منى عبد الوهاب خليل
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: Patients are considered to be the best source of information about a hospital system’s communication, education, and pain - management processes. Patients' satisfaction has become an important indicator in measuring the quality of care rendered to the patients while in hospitals. A descriptive Cross - Sectional study design is carried throughout the present study from November 11th, 2014 to July 2nd 2015, to assess of patients' satisfaction with nursing care provided at medical and surgical wards, and to determine the relationship between the satisfaction levels of patients with their demographic variables. A Non Probability "purposive" sample of (150) patients were included in the present study. The data was collected through the utilization of a developed questionnaire (Arabic version) and by means of interview with each patient included in the present study. The final copy of the questionnaire consists of the following parts : the first part is composed of patient's demographic data sheet. Second part includes the Patient's Satisfaction form. Validity of the study instrument was determined through the panel of (14) experts, and the reliability of the study questionnaire through the pilot study. Descriptive and inferential statistical analyses procedures were used for data analyses. The study demonstrated that there was an accepted satisfaction among the nurses - patient's communication, also with nursing care domain. In addition, the study subjects were satisfied with the skills and competency of the nurses in performing nursing care procedures. There was a non - significant relationship between the patient’s satisfaction with nursing care domain and all of the demographic variables, except with the study subject’s gender, levels of education, occupation, and monthly income. The study concluded that majority of the study sample were satisfied with nursing care provided in medical and surgical wards at studied hospitals. Except the patients' gender, levels of education, occupation, and monthly income had effect on. The study recommended to nursing administrators and nurses that they can utilize the findings of the present study to recognize the strengths and weaknesses of nursing care services and adopt necessary measures in enhancing quality of nursing care to increase patient satisfaction. More emphasis to be put on importance of patients satisfaction especially with nursing care in the curriculum of medical and nursing colleges as well as health institutes and nursing schools.

تقييم مطاوعة المرضى للنظام العلاجي عند الاصابة بامراض القلب التاجية في مدينة النجف == Assessment of Patients Compliance Regarding Therapeutic Regime with Coronary Heart Disease in Al - Najaf City

Author name: احمد كاظم خشالة الزرفي
Supervisor name: فخرية جبر محيبس الزبيدي
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: امراض القلب التاجية, ايضا تعرف بامراض الشرايين التاجية وسببها ترسب او تراكم اللويحات على جدران الشرايين وتعرقل سريان الدم الغني بالاوكسجين للوصول لعضلة القلب وتكون هذة اللويحات خليط من الدهون والاملاح. هذة الامراض تعتبر مشكلة صحية في جميع دول العالم، وتؤثر على اغلب السكان وخاصة في دول العالم النامية وتصيب البالغين وليست كبار السن فقط.المنهجية : - اجريت دراسة وصفية في محافظة النجف /مركز النجف لجراحة القلب والتداخل القسطاري, للفترة من الرابع من كانون الاول, 2014 ولغاية السابع والعشرون من ايار, 2015, لتقييم مطاوعة المرضى للنظام العلاجي المصابين بامراض القلب التاجية. وتحديد العلاقة بين الصفات السكانية المتعلقة بالمرضى, ونوع المرض, والعوامل الاجتماعية والاقتصادية, ومدى مطاوعة المرضى للنظام العلاجي واتباعه. اخذت عينة "غرضيه" متكونة من (150) مريضا يعاني من امراض القلب التاجية, من اللذين زاروا مركز النجف لجراحة القلب والتداخل القسطاري, جمعت المعلومات من خلال استخدام الاستبانة التي تم تطويرها بعد تحديد صدقها وثباتها وباستخدام تقنية المحاورة مع المرضى. حددت ثبات استمارة الاستبانة من خلال اجراء الدراسة المصغرة وحددت مصداقيتها من خلال مجموعة مكونة من (19) خبير. وتم وصف وتحليل البيانات باستخدام اساليب الاحصاء الوصفي والاستنباطي.النتائج : - اظهرت نتائج الدراسة ان التقييم النهائي لالتزام المرضى بالنظام العلاجي كان مناسب. بالاضافة الى ان التقييم النهائي للعوامل الاجتماعية والاقتصادية وتاثيرها على التزام المرضى بالنظام العلاجي كان مناسب ايضا.الاستنتاج : - اوجدت الدراسة ان هنالك تاثير للعوامل المتعلقة بالمرضى, والعوامل المتعلقة بالمعالجة والمرض, والعوامل الاجتماعية والاقتصادية على مطاوعة المرضى المتعلق بالنظام العلاجي عند الاصابة بامراض القب التاجية. التوصيات : - اوصت الدراسة بان الارشاد والمتابعة يجب ان يستمر، على سبيل المثال في الزيارات المنزلية عن طريق الزائر الصحي، العيادات الاستشارية او البطاقة الصحية يمكن ان تساعد المرضى على التاقلم مع النظام العلاجي. يجب ان تكون هنالك خطة تثقيفية صحية لتوعية المرضى لكي يكون استجابتهم بشكل افضل وبتحسن مستمر. بالاضافة, الاعلام والبرامج الصحية ووحدات تتعزيز الصحة يجب ان يكون لها دور بارز في زيادة المعرفة والادراك والوعي لدى الناس حول امراض القلب التاجية مثل (الذبحة الصدرية, واحتشاء العضلة القلبية) ومخاطر هذة الامراض واهمية مطاوعة المرضى للنظام العلاجي. علاوة على ذلك بناء نظام واساليب خاصة تتقالم وتنسجم مع المتابعة ووضع حلول لهذة المشاكل المتعلقة بمطاوعة المرضى للنظام العلاجي. | Coronary heart disease (CHD) also referred to as coronary artery illness, is caused by the buildup of plaque within the arteries that source oxygen - rich blood for the heart. Plaque, a number of fat, cholesterol, and calcium deposits, can develop in the arteries over a long time. They are the leading causes of death in both developed and developing countries, accounting for approximately one third of all deaths worldwide. All age groups may die from a heart attack. But older people are more inclined to die than younger people.Methodology : - Descriptive study is carried out in Al - Najaf City at Al - Najaf Center for Cardiac Surgery and Trans Catheter Therapy, from December, 4th, 2014 to May, 27th, 2015, in order to assess patients compliance regarding therapeutic regime with coronary heart disease in Al - Najaf City, and to find out the association between the demographic data, clinical data, social and economic statuses, and the patients' compliance to the therapeutic regime. A Non - Probability (Purposive Sample) of (150) coronary heart disease patients, those who visit Al - Najaf Center for Cardiac Surgery and Trans Catheter Therapy, the data were collected through the utilization of the developed questionnaire after the validity and reliability are estimated, and by means of interview technique. Reliability of the questionnaire is determined through a pilot study and the validity through (19) experts. The data analyzed through the use of the descriptive and inferential statistical analysis procedures.Result : - The findings of the present study indicated that the overall assessment for the patient’s compliance therapeutic regime is fair, also the social and economic factors and the patients' compliance therapeutic regime with coronary heart disease is fair.Conclusion : - The study concluded that there is a strong effect of the patient's centered of the disease and therapy, and the social and economic factors, on the patient's compliance therapeutic regime with coronary heart disease.Recommendations : - The study recommended that reinforcement should be employed (e.g., home visits, visits outpatient’s of the medical center) may help patients to cope with their therapeutic program. Should be the recommendations must participate in the educational insurance policy for patients so as to improve their compliance. In addition health oriented mass media approach should be employed to increase population knowledge and awareness of coronary heart disease (e.g. angina, myocardial infarction) and the importance of the patient’s compliance therapeutic regime. Moreover establishment of special policies which deal with the monitoring and managing the problems associated with the patients' compliance to the therapeutic regime.

فاعلية التمرينات التنفسية في التقليل من الم الولادة عند النساء البكريات في مستشفيات الحلة التعليمي == Effectiveness of Breathing Exercises on Reduction of Labour Pain among Primi Gravida Mothers at Hilla Teaching Hospitals

Author name: فوزية محمد نطاح الثويني
Supervisor name: وفاء عبد الكريم عباس
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: خلفية الدراسة/ تساعد الطرق العلاجية وغير العلاجية المتنوعة المراة في تحمل الم الولادة . واحد هذه الطرق المهمة لتخفيف الم الولادة الطبيعي هو تمارين التنفس. تمارين التنفس هي واحدة من اكثر الطرق الشائعة المستخدمة لتخفيف الالم الطبيعي خلال المرحلة الاولى من الولادة التي تستطيع تحفيز الاسترخاء البدني بواسطة تقليل الشد العضلي وتحفيز الاسترخاء العاطفي بواسطة تقليل الالم . الهدف/ لتحديد فاعلية التمارين التنفسية في التقليل من الم الولادة عند النساء البكرياتطريقة العمل /استخدمت الدراسة تصميم التجربة ، عشوائيا اختيرت مستشفى بابل التعليمي للنسائية والاطفال. تم جمع العينة من 2 كانون الاول 2014 الى الاول من اذار 2015. اختيرت (100) امراة بكرية شخصت في المرحلة الاولى من الولادة قسمت الى مجموعتين (50) كعينة تجريبية و(50) كعينة ضابطة .استخدم في هذه الدراسة مقياس التماثلية البصرية للالم وانواع مختلفة من تمارين التنفس .النتائج : اشارت نتائج الدراسة الى ان مستوى الالم كان اقل معنويا (p≤ 0.05) في نوع التنفس العميق البطيء مقارنة بالنوعين الاخرين .يزداد الالم في المجموعتين لكن اقل في مجموعة الدراسة من المجموعة الضابطة التي وصل الالم فيها تقريبا اعلى مستوى من مقياس الالم. اوضح تقييم مقياس الالم باستخدام مقياس التماثلية البصرية للالم (VAS ) كل 30 دقيقة ان النساء في مجموعة الدراسة كانت معنويا منخفضة القياس p≤ 0.05)) مقارنة بالمجموعة الضابطة. الاستنتاجات/ الالم كان اقل في مجموعة الدراسة باستخدام انواع مختلفة من تمارين التنفس في المرحلة الاولى من الولادة بين النساء البكريات. التوصيات/ استخدام تمارين التنفس ضمن التدريب العملي التمريضي خلال مرحلة ما قبل الولادة (مرحلة الحمل) والمرحلة الاولى من الولادة ومن خلال وسائل الاعلام . | Background : A variety of non - pharmacologic and pharmacologic methods that help the woman to cope with the pain of labour. One important method of natural labour pain relief is breathing exercises . Breathing exercises is one of the most common methods used for natural pain relief during first stage of labour that can promote physical relaxation by reducing muscle tension and promotes emotional relaxation by reducing pain . Objective : To determine the effectiveness of breathing exercises on reduction of labour pain among primi gravida mothers.Methodology : The study is a quasi - experimental design ,randomly selected Babylon Teaching Hospital for Maternity and Pediatric. Sample were collected on 2ed December /2014 to the 1st of March /2015. (100) primi mothers were selected in first stage of labour , divided into two groups (50) primi mother as study group , while (50)primi mother as control group. The pain scale (VAS) and different types of breathing exercises were used in this study.Results : The result of this study showed that the level of pain was significantly lower at (P≤0.05) in the Slow Deep Breathing type than other two types. The pain in both groups were increased, but less in the study group than the control group in which the pain reach approximately maximum level of pain score. Assessment of pain score by visual analogue scale every 30 minute, revealed that the mothers in study group have significantly lower score at (P≤0.05) than in control group. Conclusions : Pain were minimum for study group by using different types of breathing exercises in the first stage of labour among primi mothers . Recommendations : Uses Breathing exercises in the nursing practices of ante - natal care and first stage of labor and through mass media

اثر البرنامج التعليمي لمخطط الولادة (البارتوغراف) على معرفة القابلات في صالة الولادة في مستشفيات كربلاء == Impact of the Partograph Teaching Program on Midwives, Knowledge in Delivery Rooms in Karbala Hospitals

Author name: منار مجيد حميد حسين
Supervisor name: وفاء عبد الكريم عباس | امين عجيل الياسري
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: البارتوغراف هو المخطط الاول لتقيم عملية الولادة صمم من قبل العالم فريدمان سنة 1954 وبعد ذلك عدل من قبل العالمين فليبوت وكاسل في 1972. ان الغرض من مخطط البارتوغراف مساعدة القابلات في تسجيل وتفسير وتحليل واستخدام البيانات لاتخاذ قرارات وتدابير سريرية بينما يكون المخاض في حالة التقدم.الاهداف : تقييم معرفة القابلات بخصوص استعمال البارتوغراف في الطور الاول من المخاض في صالة الولادة .المنهجية : اختبار شبه تجريبي وجد للتاثير على الدراسة الحالية. تتكون عينة الدراسة من جميع القابلات اللاتي يعملن في صالات الولادة في مستشفى النسائية والتوليد التعليمي ومستشفى الهندية العام في مدينة كربلاء المقدسة . الية اختيار العينة في هذه الدراسة هي عينة غير احتمالية ملائمة. تتكون من 50 قابلة يعملن في صالة الولادة في مستشفيات مدينة كربلاء. يتكون الاختبار من 25 فقرة تتعلق بمعرفة القابلات بمخطط البارتوغراف . النتائج : اظهرت نتائج الدراسة ان 88% من القابلات لا تمتلك معرفة بخصوص مخطط البارتوغراف في مجموعة الدراسة و92% في المجموعة الضابطة و12 % من القابلات تمتلك معرفة مناسبة حول المخطط في مجموعة الدراسة و8% في المجموعة الضابطة. بينما كانت 80% من القابلات تمتلك معرفة جيدة في مجموعة الدراسة بعد تنفيذ البرنامج التعليمي بخصوص المخطط الولادي . الخاتمة : ان معرفة القابلات بخصوص المخطط الولادي تزداد بعد التداخل ( البرنامج التعليمي) وهذه النتائج اوضحت ان التعليم الجماعي فعال جدا في تحسين وتطوير معرفة القابلاتالتوصيات : تحسين معرفة القابلات بالمخطط الولادي (البارتوغراف) بواسطة الاستعمال المستمر للبرامج التعليمية والتدريب وورشات العمل لجميع القابلات وخصوصا في صالات الولادة . | Background : Partograph was first graphic used to assess the progress of labour designed by Friedman in 1954 and further developed by Philpott and Castle in1972. The role of the partograph, is to aid midwives record, understand, analyze, and use information to make medical management judgments while labor is in progress. Objective : To assess midwives knowledge of the use of partograph in first stage of labor in delivery room. Methodology : Quasi experimental design was found to be effective for the present study. In this study, the target population consisted of all midwives working in delivery rooms in hospitals of Holy Karbala city. The sampling technique used in this study was non probability convenience method of sampling , the sample consisted of 50 midwives working in delivery rooms in Maternity Teaching Hospital and Al - Hindyia General Hospital in Karbala City. There were 25 items regarding knowledge of partograph. The data analyzed through the use of the descriptive and inferential statistical analysis procedures. Results : the results of the study reveal that (88%) of midwives have poor knowledge regarding partograph in study group and (92%) in control group,12%have fair knowledge in study group and 8% in control group, 80% of midwives have good knowledge in study group after implementation of teaching program regarding partograph. The result revealed that the knowledge of midwives regarding partograph is increased after the intervention. Conclusion : The finding revealed that the teaching program was very effective in increasing midwives knowledge regarding the use of partograph.Recommendation : Enhance the midwives knowledge regarding partograph by frequent application of teaching program, training course and workshop for all midwives, especially in the delivery room By Ministry of Health (MOH).

تقييم الحالة النفسية الاجتماعية عند الايتام في دور الرعاية في مدينة بغداد == Assessment of psychosocial status of orphans in orphanages in Baghdad city

Author name: علي احمد كاظم الحطاب
Supervisor name: سجاء هاشم محمد الربيعي
General topic: Medicine
Specific topic: Nursing
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: دراسة وصفية تحليلية اجريت لتقييم الحالة النفسية الاجتماعية عند الايتام في دور الرعاية في مدينة بغداد للفترة من تشرين الاول 2014 ولغاية اغسطس 2015.اختيرت عينة غرضية (غير احتمالية) كان قوامها (50) يتيم لهذه الدراسة.بنيت الاستبيانية لتحقيق اهداف هذه الدراسة التي تتالف من جزئين ,الاول يتضمن المعلومات الشخصية,والثاني الحالة النفسية الاجتماعية.جمعت العينة باستعمال الاستبانة وبطريقة المقابلة الشخصية للاطفال الايتام . من 9 كانون الثاني2015 ولغاية 20 شباط 2015.تم تحليل البيانات من خلال تطبيق التحليل الاحصائي الوصفي (النسب المئوية، التكرارات، متوسط الانحراف المعياري والتحليل الاستنتاجي (اختبارات مربع كاي) مع نظام الحزمة الحصائية للعلوم الاجتماعية (الاصدار 20).اشارت نتائج الدراسة جميع الايتام كانوا متاثرين بالمشاكل النفسية الاجتماعية بمستويات مختلفة,عدم وجود دلالة احصائية بين الجنس والمشاكل النفسية الاجتماعية , اشارت اغلب نتائج الدراسة ان هناك علاقة قوية بين المعلومات الشخصية والحالة النفسية الاجتماعية, هناك علاقة قوية ذات دلالة احصائية بين المشاكل النفسية والمشاكل الاجتماعية.في ضوء الدراسة نتائج اوصى الباحث على توعية الايتام حول التاثير السلبي للمشاكل النفسية على حياتهم ومواجهة كل انواع الحالات الصعبة من فقدان الابوين في الحياة، برامج تثقيفية ضرورية للمسؤولين عن دار الايتام لزيادة معرفتهم نحو المشاكل النفسية , دليل خاص حول التثقيف الدين والاخلاق متخصص للحد من الصراع ما بين الايتام وتطور المشاكل النفسية الاجتماعية. | A descriptive analytical study was carried out to assess of psychosocial status of orphans in orphanages in Baghdad City from October 2014 to August 2015.A purposive (non - probability) sample of (50) orphans was selected for the present study.A questionnaire was constructed to achieve the objectives of this study, which consists of two parts the first is one sociodemographic data, the second psychosocial status.Data were collected through the use of the constructed questionnaire and the process of interviewing the orphans children and used as data collection from 9th January 2015 to 20th February 2015. Data were analyzed through the application of descriptive statistical analysis (percentage, frequency, mean of score and S.D) and inferential data analysis (Chi - square) with (SPSS, Version 20).The results of the present study indicated that all orphans are affected by the psychosocial problems in different levels, there are non - significant differences between females and males as variable gender group with psychosocial problems, the most findings of the study indicated that there were high significance between sociodemographic and psychosocial status, psychological problems had a high significant relationship with social problems.In the light of these findings, the researcher recommended that educate the orphans about the psychological effects and its negatively impacts on their lives to face all kinds of difficult conditions in which they live from the loss of their parents, an educational program is necessary to those who were responsible about the orphanage to increase their knowledge toward the psychological problems, guidance towards religious and moral education specialist to reduce the conflict between the orphans and development of psychosocial problems.

دراسة جزيئية وبكتريولوجية لبكتريا Porphyromonas gingivalis المعزوله من المرضى المصابين بامراض اللثه == Molecular and Bacteriological Study of Porphyromonas gingivalis Isolated from Patients with Periodontitis

Author name: فاطمة مالك عبود
Supervisor name: محمد صبري عبد الرزاق السعيد | الهام عباس بنيان
General topic: Medicine
Specific topic: Microbiology
Degree: Doctorate
Language: English
University location: Babylon
First pages:
Abstract: تم جمع 103عينة من الصفيحة الجرثومية العميقة (subgingival dental plaque) من المرضى الذين يعانون من التهاب اللثة المزمن والمتقدم (72, 31) على التوالي لمراجي العيادة الاستشارية لامراض اللثة في كلية طب الاسنان/ جامعة بابل والمركز التخصصي لطب الاسنان في مدينة الحلة. للفترة من كانون الاول 2013 الى حزيران 2014. تم تشخيص وعزل بكتريا P. gingivalis بطرق مختلفة منها استخدام الطرق البكتيرية التقليدية واظهرت النتائج ان 69.5%) 16) منها تم عزلها من التهاب اللثة المزمن وتم عزل 7 (30.5) من التهاب اللثة المتقدم باستخدام التنمية على الوسط الانتقائي الخاص لهذه البكتريا. وكذلك تم استخدام طريقة التشخيص الجزيئي باستعمال المعلم الوراثي المستند على دور جين 16s rRNA حيث اظهر ان12 عزلة من اصل 23 عزلة تم تشخيصها بشكل نهائي انها تعود لبكتريا P. gingivalis. منها حوالي 8 تعود الى التهاب اللثة المزمن و4 تعود الى التهاب اللثة المتقدم. بالاضافة الى ذلك, تم التحري عن قابلية هذه البكتريا للالتصاق(adherence ability) بالخلايا الطلائية المبطنة للفم حيث وجد ان جميع العزلات لها القابلية على الالتصاق بهذه الخلايا وتم ايضا اختبار قابليتها على انتاج انزيم (Gingpain) ووجد ان جميع العزلات منتجة الى هذا الانزيم.في هذه الدراسة تم التحري المظهري عن عملية تكوين الاغشية الحيوية(Biofilm formation) للعزلات المدروسة باستخدام فحص tissue culture plate test (TCP) اذ كانت مكونة للاغشية الحيوية بنسبة 100% وكذلك تم فحص تاثير بعض المواد المستخدمة في طب الاسنان على انتاج biofilm ووجد ان اعلى تثبيط سجل للكلورهكسدين (غسول الفم) والشب (Alum)ويليه تاثير Clove مقارنة باقل تاثير لمادة السعد ((Cyprus rotundus. وكذلك تم الكشف عن حساسية العزلات لبعض المضادات الحيوية ووجد بان كل العزلات كانت حساسة الى Co - amoxiclave وعلى العكس اغلب العزلات تظهر مقاومة عالية لل Amoxicillin بينما سجلت مقاومة قليلة جدا لل Ampicillinو Metronidazole(16.3%, 20.3%, ) على التوالي. واخيرا تم فحص تاثير بعض المواد المستخدمة في طب الاسنان على تثبيط نمو هذه البكتريا وتوضح النتائج ان اعلى تاثير سجل للكلورهكسدين (غسول الفم) والشب (Alum)ويليه تاثير القرنفل(Clove) mm) 25,30,40) على التوالي مقارنة باقل تاثير لمادة السعدC. rotundus (10mm) .في هذه الدراسة ايضا تم التحري عن التغاير الجيني ((TLR - 4 Polymorphisms باستخدام تقنية البلمرة والقطع بالانزيم ((PCR - RFLP. وتبين من النتائج وجود ثلاث انماط جينية في موقع طفرة Thr399Ile : CC وCT وTT ، اذ بلغت نسبة انتشارها ((12.5%,10%,77.5% في مجموعة المرضى على التوالي بينما هناك فقط نمطين في مجموعة السيطرة TT,CCوبنسبة انتشار(36.6% ,63.4%) على التوالي ، فيما بلغت نسبة انتشار الاليلC السائد في المرضى 82.5 % بالمقارنة للسيطرة 63.3% مع وجود اختلاف معنوي. وفي المقابل سجل وجود ثلاث انماط جينية في موقع طفرة Asp299Gly : AA وAG وGG وبنسبة انتشار % 67.5 و12.5% و20% في مجموعة المرضى على التوالي بينما هناك فقط نمطين في مجموعة السيطرة GG, AA وبنسبة انتشار34.4%) 66.6%,) على التوالي. حيث سجلت نسبة انتشار الاليل A السائد (73.75%) في مجموعة المرضى بالمقارنة بمجموعة السيطرة (66.6%) وبفرق معنوي. | In this study, 103 clinical samples were collected from subgingival dental plaque of patients with chronic (CP) and aggressive periodontitis (AP) (72 and 31) respectively, and (n=30) a healthy group admitted to teaching Hospital in college of Dentistry / Babylon University and specialized center of Dentistry in Hilla city, From February 2013 to June 2014). Out of which (n=40) with a chronic periodontitis group from them blood sample were collected for detection of gene polymorphisms in Toll - like receptor - 4 (TLR - 4). These dental plaque samples were subjected to different methods for identification of P. gingivalis mainly traditional bacteriological method. It was found that 23 P. gingivalis isolates were recovered by using selective media where 19 isolates (26.3%) obtained from (CP) and 4 isolates (12.5%) from (AP). Furthermore, molecular detection method was applied by using 16s rRNA gene as a genetic marker for confirmation of detection of P. gingivalis isolates, 12 isolates of P.gingivalis out of 23were detected by molecular method focusing on the role of 16s rRNA gene of P. gingivalis. 8 isolates were isolated from CP, and 4 isolates were isolated from AP subgingival plaques. In addition, these 12 isolates were investigated to detect Adherence of P.gingivalis to oral epithelial cells. The result showed that all isolates have ability to adhere to oral epithelial cells. The study also detected the ability of this bacteria for production of Gingipain, it was found that all isolates were positive for this enzyme at a rate 100%.Furthermore, biofilm formation was tested in the semi quantitative microtiter plate test. The results revealed that all isolates were biofilm former, high and moderate biofilm formation mode were accounted for (50%) while there are no isolates that express non biofilm formation.Regarding to effect of Chlorhexidine (CHX) gluconate (0.12%) on biofilm formation, the results of this study demonstrated (CHX) effectively and reduced the viability of biofilm - forming bacteria from moderate to 25%, weak to 75% and no strong. The study was also evaluating the effect of some plant extracts on biofilm formation. The results showed the highest effect for Alum potassium phosphate followed by Clove, in contrast to lowest effect of C. rotundus. And after screening the effect of Flagyl solution on production of bacterial pigment. The results showed that the metronidazole produced the highest inhibition activity range (30 - 10mm). Furthermore, the susceptibility of isolates to a variety of antibiotics had been investigated and it had been found that all isolates were sensitive to co - amoxiclave and, in contrast, the isolates showed high resistance to other type of beta lactam such as amoxicillin (54.3%). In addition, the result showed that the resistance of p. gingivalis was very low for ampicillin and metronidazole (16.3% and 20.3%), respectively.The screening of antimicrobial activity of (CHX) gluconate (0.12%) was carried out and the results showed that it produced the highest inhibition activity whether against p. gingivalis with inhibition zone range 40 - 15mm. Finally in vitro antibacterial activity of Alum, Clove and Cyperus rotundus plant extracts was studied and the results revealed that all tested isolates were inhibited by aqueous extracts at 50% concentration. The maximum inhibition zone was observed in Alum and Clove extracts respectively (30mm, 25mm), compared to the minimum inhibition by Cyperus rotundus (10mm). The antibacterial actions of 20% concentration of plant extract gave lower inhibition zone than 50% concentration of that extract which represented by (19mm, 16mm, and 10 mm) of the previous three mentioned extracts. This study also aimed to investigate the association of Thr399Ile and Asp299Gly single nucleotide polymorphisms (SNPs) in the (TLR - 4) with the incidence of (CP).The results revealed at the site of SNPThr399Ile, there were three genotypes for this SNP among CP patients; CC, CT and TT with frequency of 77.5%, 10% and 12.5 % respectively, whereas, there were only two genotypes among control group; CC and TT with frequency of 63.4% and 36.6% respectively with no significance differences between patients and control. However, the frequency of allele C (dominant) was higher among CP group (82.5%) than control (63.3) with significant difference. The site of SNP of Asp299Gly also showed three genotypes among CP patients; AA, AG and GG with frequency of 67.5%, 12.5% and 20% respectively, whereas, there were only two genotypes among control group; AA and GG respectively with frequency of 66.6 and 34.4% respectively with no significance differences between patients and control. However, the frequency of allele A (dominant) was higher among CP group 73.75 % than control 66.6%.

الجهد الوقائي والمضاد للاكسدة للمونتيلوكاست والاومبرازول على القرحة المعدية المستحدثة بحامض اسيتيل ساليسيلك في ذكور الارانب == Gastroprotective and Antioxidant Potential of Montelukast and Omeprazole Against Acetyl Salicylic Acid Induced Gastric Ulcer Model in Male Rabbits

Author name: علي حسن زكي عجام
Supervisor name: نسرين جلال محمد البياتي | مفيد جليل عوض
General topic: Medicine
Specific topic: Medicines and Toxins
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: قرحة المعدة هي واحدة من الامراض الاكثر انتشارا في العالم, تحدث عندما يتم فقدان الموازنة بين بعض العوامل العدوانية والوقائية . مضادات الالتهاب اللاستيرويدي هي معروفة كواحدة من العوامل الامراضية الاكثر شيوعا المقترنة بقرحة المعدة وذلك بان عقار المونتيلوكاست له اثار مفيدة في الحماية من تقرح الغشاء المخاطي المبطن لجوف المعدة المستحدث .اجريت هذه الدراسة في كلية الطب - جامعة بابل للفترة من كانون اول الى 2013حزيران 2014 وتهدف الى تقييم التاثير الوقائي لبطانة المعدة وفعالية مضادات التاكسد لعقار المونتيلوكاست بالمقارنة مع عقار الاومبرازول في نموذج لقرحة معدية مستحدثة بواسطة حامض استيل ساليسيليك ( حامض الصفصاف ) في ذكور الارانب . تم استخدام ثمانية واربعين من ذكور الارانب المحلية في هذه الدراسة التي تنقسم الى قسمين : 1 - الدراسة التجريبية : بعد اسبوعين من التاقلم, الحيوانات ( ثمانية عشر ارنبا ) قسمت بشكل عشوائي الى ثلاث مجاميع (ستة ارانب في كل مجموعة) واخذت العلاج بالشكل التالي : الحيوانات في المجموعة الاولى اعطيت حامض استيل ساليسيليك 250 ملغم/كغم عن طريق الفم , المجموعة الثانية اعطيت حامض استيل ساليسيليك 500 ملغم/كغم عن طريق الفم, المجموعة الثالثة اعطيت حامض استيل ساليسيليك 750 ملغم/كغم عن طريق الفم, على شكل جرعة واحدة فقط.2 - الدراسة الفعلية : بعد اسبوعين من التاقلم, هذه الحيوانات( ثلاثون ارنبا ) قسمت بشكل عشوائي الى خمس مجاميع (ستة ارانب في كل مجموعة) واخذت العلاج بالشكل التالي : مجموعة السيطرة الطبيعية : اعطيت ماء" مقطرا" عن طريق الفم , مجموعة السيطرة الفعالة : اعطيت حامض استيل ساليسيليك 500 ملغم/كغم بشكل جرعة واحدة ,مجموعة المعالجة بعقار الاومبرازول : اعطيت اومبرازول 20 ملغم/كغم عن طريق تجويف البطن(بيريتون) , مجموعة المعالجة بعقار المونتيلوكاست : اعطيت مونتيلوكاست 20 ملغم/كغم عن طريق الفم , مجموعة المعالجة بعقار المونتيلوكاست فقط : اعطيت فقط مونتيلوكاست 20 ملغم/كغم عن طريق الفم. يتم اعطاء عقار الاومبرازول والمونتيلوكاست مرة واحدة يوميا لمدة ثلاثة ايام وبعد ساعة من اخر جرعة( اليوم الثالث) لتلك الادوية يتم اعطاء حامض استيل ساليسيليك بجرعة 500 ملغم/كغم بعد ذلك يتم قتل الحيوانات بعد 5 ساعات . بعد ذلك يحضر مزيج النسيج المعوي ويستخدم لتحديد مؤشرات هذه الدراسة مثل تركيز المالونديلدهايد وليكوترين دي 4وليكوترين بي 4 وفعالية كل من زانثين اوكسيديز((XO وسوبراوكسايد دسميوتز((SOD وجلوتاثايون بيروكسيدز ( ( GPX وجلوتاثايون اس ترانسفيرز ( (GSTبالاضافة الى تحضير مقاطع نسيجية للمعدة لاختبارها تحت المجهر الضوئي.تضمنت نتائج هذه الدراسة ان حامض استيل ساليسيليك زاد كل من معامل القرحة وتركيز ليكوترين بي 4 وليكوترين دي4 بصورة معنوية وانخفاضا معنويا في معامل الاكسدة الحساس مقارنة مع مجموعة السيطرة الطبيعية بينما الاومبرازول والمونتيلوكاست يظهران انخفاضا معنويا في معامل القرحة وتركيز ليكوترين بي4 وليكوترين دي4 وارتفاعا معنويا في معامل الاكسدة الحساس مقارنة مع مجموعة السيطرة الفعالة . حامض استيل ساليسيليك زاد من تركيز المالونديلدهايد وفعالية انزيم زانثين اوكسيديز بصورة معنوية بالتزامن مع انخفاض معنوي في فعالية كل من سوبراوكسايد دسميوتز وجلوتاثايون بيروكسيدز وجلوتاثايون اس ترانسفيرز مقارنة مع مجموعة السيطرة الطبيعية . اظهرعقار الاومبرازول انخفاضا معنويا في تركيز المالونديلدهايد وانخفاضا غير معنويا في فعالية انزيم زانثين اوكسيديز بالتزامن مع ارتفاع معنوي في فعالية كل من سوبراوكسايد دسميوتز وجلوتاثايون بيروكسيدز وجلوتاثايون اس ترانسفيرز مقارنة مع مجموعة السيطرة الفعالة, علاوة على ذلك اعطاء عقار المونتيلوكاست يسجل انخفاضا معنويا في تركيز المالونديلدهايد وفعالية انزيم زانثين اوكسيديز بالتزامن مع ارتفاع معنوي في فعالية كل من سوبراوكسايد دسميوتز وجلوتاثايون بيروكسيدز وجلوتاثايون اس ترانسفيرز مقارنة بمجموعة السيطرة الفعالة.على مستوى الفحص النسيجي اظهرت النتائج عدم وجود تقرح في معد مجموعة السيطرة الطبيعية بالمقارنة بمعد مجموعة السيطرة الفعالة التي تظهر بان هناك تقرحا" شديدا" ونزف" متمثلا بنخر الغشاء المخاطي المبطن للمعدة مترافقة مع وذمة في الطبقة تحت المخاطية وارتشاحات خلوية التهابية . عند اعطاء عقار الاومبرازول الطبقة الطلائية المخاطية تبدو تشابه التركيب الطبيعي واقل نزيفا من مجموعة السيطرة الفعالة . فيما يخص عقار المونتيلوكاست تقرح الغشاء المخاطي المعدي يظهر اقل تاثيرا مع وقاية اقل من تاثير الاومبرازول . اعتمادا على نتائج هذه الدراسة نستنتج بان حامض استيل ساليسيليك بجرعة 500 ملغم/كغم احدث بصورة ناجحة قرحة في المعدة والليكوترين قد يكون مسؤولا" عن تلف الجدار المخاطي المعدي الحاد المستحدث بواسطة حامض استيل ساليسيليك . عقار المونتيلوكاست بجرعة 20 ملغم/كغم عن طريق الفم له دور مهم في حماية الجدار المخاطي المعدي من التلف بواسطة حامض استيل ساليسيليك وذلك قد يعزى الى قابليته في معادلة حالة الاكسدة ومضادات الاكسدة ويقلل من تاثير الليكوترين وتاثيره المثبط على ارتشاح الخلايا الالتهابية . | Gastric ulcer is one of the most widespread diseases in the world. It occurs when the balance between some aggressive and defensive factors is lost. NSAIDs are known as one of the most common pathogenic factors associated with gastric ulcer. Montelukast was reported to have beneficial effects in the management of experimental gastric mucosal ulceration.The present study was carried out in the Collage of Medicine, University of Babylon from December 2013 to June 2014 and aimed to evaluate the gastroprotective effect and the antioxidant activity of montelukast in comparison with omeprazole in a model of acetylsalicylic acid - induced gastric ulcer in male rabbits Forty - eight local domestic male rabbits were used in this study . This study was divided into two parts : 1. Pilot study design : After two weeks of adaptation period, the animals(18 rabbits ) were randomly separated into 3 groups (6 rabbits in each group) and treated as follows : Group A : received ASA (250 mg/kg ,orally) ,Group B : received ASA (500 mg/kg ,orally) and Group C : received ASA (750 mg/kg ,orally), as single dose . 2. Active study design : After two weeks of adaptation period, the animals ( 30 rabbits) were randomly separated into 5 groups (6 rabbits in each group). Normal control group received distilled water orally , active control group received ASA (500 mg/kg b.w. ) as single dose ,omeprazole pretreated group received omeprazole (20 mg/kg b.w.) intraperitoneally , montelukast pretreated group received montelukast (20 mg/kg b.w.) orally and montelukast alone treated group received montelukast alone ( 20 mg/kg b.w) orally. The omeprazole and montelukast were continually given once daily for 3 days. After one hour of the last dose( 3rd day ) of 36 hours fasted animals , acetylsalicylic acid was administered orally to the animals ( except normal control group and montelukast alone treated group) in a dose of ( 500 mg / kg b.w.) , then all the animals were sacrificed 5 hour later. Gastric tissues homogenate prepared and used to determine the parameter of this study as malondialdehyde (MDA) concentration, leukotriene D4 (LTD4) and leukotriene B4( LTB4) concentration, Xanthine oxidase( XO), superoxide dismutase (SOD), glutathione peroxidase (GPX) and glutathione S transferase ( GST) activities. Furthermore, stomach tissue sections were prepared for histological examination.The results of present study include the ASA significantly (P< 0.05) increase the ulcer index, leukotriene D4, leukotriene B4 concentrations and significantly(P< 0.05) decrease in the oxido - sensitive index when compared with the normal control group. While omeprazole and montelukast showed a significant (P< 0.05) decrease in ulcer index ,leukotriene D4 , leukotriene B4 concentration and significant(P< 0.05) increase in oxido - sensitive index when compared with the active control group. ASA, significantly increased the gastric tissue MDA concentration and XO activity (P< 0.05) concomitantly with decreased SOD, GPX,GST activity (P< 0.05), when compared with the normal control group. Omeprazole showed a significant decrease in gastric tissue MDA concentration (P< 0.05) and no significant decrease in XO activity (P> 0.05) concomitantly with a significant increase in gastric tissue SOD, GPX,GST activity (P< 0.05), when compared with the acetylsalicylic acid treated group. Moreover, the administration of montelukast significantly decreased both gastric tissue MDA concentration and XO activity (P< 0.05) concomitantly with significant increase in gastric tissue SOD, GPX,GST activity (P< 0.05), when compared with the active control group . Microscopically , the results showed that there is no lesion in the stomachs of normal control group in contrast to the stomachs of active control group that show severe ulceration and hemorrhage as represented by necrosis of gastric mucosa associated with submucosal edema and inflammatory cell infiltrate. Upon omeprazole pretreatment, the mucosal epithelium had near normal architecture and there is less hemorrhage than active control group . Regarding montelukast, the lesion of gastric mucosa show less severe effects with protection less than the effects of omeprazole. According to the results obtained in this study , it can be concluded that acetylsalicylic acid in dose of 500 mg/kg successfully induced ulcers in stomach. leukotrienes may be involved in the pathogenesis of acute gastric mucosal damage induced by ASA . Montelukast in doses of 20 mg/kg orally has an important role in the protection from ASA induced gastric mucosal damage and this can be attributed to its ability to balance oxidant - antioxidant status and to reduce the effects of leukotriene as well as its inhibitory effect on inflammatory cell infiltration in gastric tissue

التقييم السريري لمستوى تراكيز الهوموسيستين وحمض الفوليك وفيتامين ب - 12في امصال مرضى البهاق == Clinical Evaluation of Homocysteine, Folic acid & B12 Concentration Levels in Sera of Vitiligo Patients

Author name: محمد نوري ابراهيم
Supervisor name: حيدر هاشم الشلاه | محمد كاظم الحطاب
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: البهاق مرض مكتسب غير معد مجهول السبب وشائع في جميع انحاءالعالم ويحدث نتيجة الفقدان التدريجي لوظيفة الخلايا الصباغية التي تنتج الميلانين (الصبغة الجلدية) مما يؤدي الى فقدان الصبغة في الجسم او الشعر او الفم ولازالت مسببات هذا المرض غير مفهومة تماما فهناك العديد من النظريات التي تبين سبب ظهوره وواحدة من تلك النظريات تعزي سبب ظهورالبهاق الى الزيادة في (الهوموسيستين) والذي قد يشارك في تدمير الخلايا الصباغية ( الميلانوسايت) في الجلد عن طريق زيادة الجهد التاكسدي.ان هذه الدراسة تبحث دورالهوموسيستين وحمض الفوليك وفيتامين ب - ١٢ وتقييم هذه الادوار في التسبب او في انتشار هذا المرض ، وقد اجريت الدراسة في مدينة مرجان الطبية في العيادة الاستشارية الخارجية للامراض الجلدية في محافظة بابل /مدينة الحلة وقد تم جمع العينات في الفترة منذ نوفمبر 2015 حتى مارس 2016 وقد شملت ثمان وثمانون حالة : اربعة واربعون منهم مصابا بمرض البهاق واربع واربعون شخصا سليما وباعمار مختلفة. وقد تم استبعاد الاعمار فوق 40سنة ومن يزيد مؤشر كتلة الجسم لديهم عن 30 وكذلك المصابين بارتفاع ضغط الدم ومرضى السكري ومرضى فقر الدم الخبيث وداءالثعلبة والاشخاص الذين لديهم خللا في الغدة الدرقية والحوامل والمرضعات والمدخنين وشاربي القهوة. وقد تم قياس مستوى الهوموسيستين والفوليك وفيتامين ب - ١٢ في مصل الدم باستعمال الطريقة اللونية على جهازي ELISA و.TOSOH - 900تم التعبير عن النتائج من خلال استخدام المعدل والانحراف المعياري . وقد تم اجراء التحليلات الاحصائية باستخدام برنامج التحليل الاحصائي (SPSS 21) وتم اعتبار قيمة الاحتمالية0.05) ≤ p) لتكون ذات دلالة احصائية.كان مستوى الهوموسيستين في الدم اعلى لدى المرضى الذين يعانون من البهاق مقارنة بمجموعة الاشخاص الغير مصابين. وكان مستوى حمض الفوليك في مجموعة المرضى اقل بكثير مما كانت عليه مجموعة الاشخاص الغير مصابين على الرغم من ان مستوى حمض الفوليك كان طبيعيا. ولم يلاحظ اي اختلاف معتد به في مستوى فيتامين ب - ١٢ بين مرضى البهاق والاشخاص غير المصابين.اما فيما يتعلق بنشاط المرض فقد كان معدل الهوموسيستين في مجموعة المرضى الذين يعانون من مرض البهاق الفعال (النشط) اعلى مما كانت عليه في مجموعة الغير مصابين وكان متوسط مستوى الهوموسيستين في مصل الدم في مجموعة المرض النشط اعلى من تلك التي في مجموعة المرض المستقر. ان نتائج هذه الدراسة اظهرت ارتفاع مستوى الهوموسيستين قي المرضى الذين يعانون من مرض نشط ومستقر ولكن ليس في المرضى الذين تماثلوا للشفاء لافتا الى وجود علاقة وطيدة محتملة بين الهوموسيستين ونشاط المرض. وفي هذه الدراسة كانت هناك فروق ذات دلالة احصائية فيما يتعلق بمستوى حمض الفوليك في مصل الدم فكان في مجموعة المرضى الذين تماثلوا للشفاء اعلى بكثير مما كانت عليه مجموعة المرض المستقر واعلى من مجموعة المرض النشط بينما لم يكن هناك اختلاف يذكر في مستوي فيتامين ب - ١٢ فيما يتعلق بنشاط المرض. وفي الختام بينت هذه الدراسة الى ان من المحتمل ان تكون هناك صلة بين ارتفاع مستوى الهوموسيستين او قلة مستوى حمض الفوليك في مصل الدم وبين التسبب في مرض البهاق او نشاطه وقد تستخدم هذه العلامات البيولوجية لقياس نشاط المرض ومعرفة مراحله. | Vitiligo is a common, acquired, multifactorial and polygenic depigmenting disorder caused by the destruction of melanocytes. The exact etiopathogenesis is unknown. There has been conflicting reports on the association between the disease and the serum levels of homocysteine (Hcy) in vitiligo and its severity. Hcy may mediate melanocyte destruction via increased oxidative damage. In the present study homocysteine, folic acid and vitamin B12 were estimated to identify their role in the pathogenesis in vitiligo. This study was carried out in Marjan Medical City in the outpatient dermatology clinic in Babylon Province, Hilla City. All samples were collected from November 2015 till March 2016. This was a case control study which included 88 subjects, forty four were patients diagnosed with vitiligo and the other forty four were healthy subjects (controls). Cases over 40 years, BMI > 30, patients who clinically and laboratory diagnosed with hypertension, pernicious anemia, diabetes mellitus (D.M), alopecia areata, thyroid dysfunction, pregnancy and lactation, coffee drinkers and cigarettes smokers were excluded. Serum levels of folic acid, B12 and homocysteine were measured by using a colorimetric method technique. The results were expressed as mean ± standard error of mean. T - test, Annova test and the linear regression analysis Rho (ρ) were used for the determination of the level of significance. Statistical analysis was performed with Statistical Package for the Social Sciences (SPSS) version 21.0 software. A P value of ≤ 0.05 was considered to be statistically significant. The results of the present study demonstrate elevated serum homocysteine levels in extensive vitiligo. Elevation of homocysteine levels was observed in patients with active as well as stable disease, but not in patients with regressive disease, pointing to a possible relationship to vitiligo activity. Also in this study there was a statistically significant difference between active, stable and regressive activity regarding folic acid, on the contrary there was no significant difference regarding vitamin B12 in the activity of the disease. In conclusion, elevation of serum homcysteine level could be related to the pathogenesis and the activity of vitiligo and it could be used as a biomarker for the measurement of disease activity and in the prognosis of vitiligo

تقييم مستوى الفتوين ا لمرضى احتشاء العضله القلبيه الحاد في محافظة بابل == Evaluation of Fetuin A level in patieints with Myocardial Infarction in Babylon Province

Author name: دينا عائد محمد الخفاجي
Supervisor name: حيدر هاشم الشلاه | عدي جاسم الصالحي
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: احتشاء العضله القلبيه الحاد سبب المضعفات المرضيه والموت بشكل واسع في العالم. احتشاء العضله القلبيه موت الخلايا القلبيه التي تحدث بعد انعزالها عن الاوكسجين لفتره طويله. تم تقييم الخطورة لهذا المرض يتم عن طريق عوامل الخطورة والواسمات الحيويه للخطورة. وتمت دراسة عدد من عوامل الخطوره والواسمات الحيويه للخطوره لتقييم زيادتها او نقصانها المعنوي, قابليتها التنبؤيه للمرض, ومدى انتشارها في مجموعة الدراسه.تضمنت الدراسة 44 مريض تتراح اعمارهم من (45 - 80) سنة وتم تشخيصهم سريريا على انهم مصابين باحتشاء العضلة القلبية الحاد , تم الحصول عليهم من خلال رقودهم في وحدة العناية التاجية المركزة لمستشفى مدينة مرجان الطبية ومستشفى الحله لتعليمي بعد ان تم ادخالهم من قبل اطباء مختصين كونهم مصابين بمتلازمة الشرايين التاجية الحادة للفتره من 1/12/ 2015 لغاية 31/4/2016. بالاضافة الى هؤلاء تضمنت الدراسة 44 شخصا سليما ظاهريا وهم مجموعة السيطرة وقد روعي في الاختيار التطابق الديموغرافي بين المجموعتين كون الدراسه ذات بروتوكول يعنى بدراسة الحالات الافرادية ومقارنتها بحالات السيطرة. تم اجراء الفحوص المختبرية في مختبرات فرع الكيمياء السريرية في كلية طب/جامعة بابل.وبمقارنة مجموعة السيطرة مع مجموعة المرضى المصابين لوحظ قلة في مستوى الفتوين للمرضى مقازنه بمجموعة السيطرة( 0.05> p )،وزياده في مستوى T.Ch,LDLوHbA1c للمرضى مقارنة بمجموعة السيطرة(p>0.05). اما فيما يتعلق بالتنبؤبحدوث احتشاء العضله القلبيه الحاد وجد ان الاشخاص الذين لديهم مستوى HbA1c وT.Cholesterol عالي في مصل الدم يكونون عرضه للاصابه بالمرض لثلاث مرات.وقد تبين ان مستوى الFA في مصل الدم للمرضىيرتبط بشكل كبير مع نوع الاحتشاءالعضلي (STEMIوNSTEMI)وهذا يؤدي الى الايحاء بانه بامكانية دراستها كواسم حيوي تشخيصي لنوع الاحتشاء العضلي في الدراسات المستقبليه. | Acute myocardial infarction causes morbidity and mortality in wide areas of the world. It is the death of cardiac cells that occurs following prolonged cutoff of oxygen. The evaluation risk of this disease by the risk factor ,the study was aimed to evaluate the role of Fetuin A level in Acute myocardial infarction and to assess Fetuin A with some of risk markers .Risk assessment is done by using risk factors and risk markers. A number of risk factors and risk markers are evaluated in the present study to determine their significance, predictive ability in the studied population. A case control study was conducted between 1st December 2015and 31st April 2016, on 44 consecutive patients aged (45 - 80) years old, diagnosed by expert physicians to have Acute myocardial infarction admitted to the coronary care units of Merjan Medical City and Al - Hilla Teaching Hospital, in addition to other (44) subjects demographicaly matched without history of any coronary disease with similar risk factors considered as a control group.The sera obtained from the blood of patients and control group subjects were used to meacure the circulating level of Fetuin A, total cholesterol, LDL, albumin, urea, creatinine ,while the whole blood was used for HbA1c measurement, as they represent a group of risk markers of AMI. In comparison with the control group, the patients with acute myocardial infarction showed a significant decrease in fetuin A (P<0.05), and significant increase in total cholesterol ,LDL, and HbA1c(p< 0.05) .Regarding prediction of acute myocardial infarction , the study revealed that patients with myocardial infarction were three times more likely to have high HbA1c and total cholesterol. It was demonstrated that high serum fetuin - A level was not significantly correlated with HbAlc ,LDL, total cholesterol in acute myocardial infarction patients . However fetuin A serum level wuas significantly correlated with type of myocardial infarction (STEM and Non - STEMI).In conclusion the evidence of decreace level of Fetuin A in acute myocardial infarction could play arole in the development of pathogenesis acute myocardial infarction.

هرموني اللبتين والرزستين وعلاقتهما مع الجهد التاكسدي في مرض البقع المزمنة للصدفية == Correlation of Leptin and Resistin with Oxidative Stress in Chronic Plaque Psoriasis

Author name: احمد محمد فاضل جواد المختار
Supervisor name: عبد السميع حسن الطائي | محمد كاظم الحطاب
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: الصدفية هو مرض جلدي شائع يصيب 1 - 3 ٪ من سكان العالم ويتميز بالتهاب مزمن في خلايا بشرة الجلد مع تغيرات غير طبيعية في نضوج الخلايا الكيراتينية. تتراكم الادلة على دور السايتوكينات بما في ذلك الاديبوكينات مثل اللبتين والرزستين في التسبب بمرض الصدفية. ومن ناحية اخرى تتزايد الادلة على شمول الصدفية في الاجهاد التاكسدي نظرا لتعرض الجلد لاصناف الاوكسجين الفعالة، والتي تلعب دورا مهما في الاستجابات الالتهابية .الاهداف : تهدف الدراسة الحالية الى تقييم مستويات هرمونات اللبتين والرزستين، اضافة الى تقدير الاجهاد التاكسدي عن طريق قياس مستويات مضادات الاكسدة الكلوتاثايون والقدرة الكلية لمضادات الاكسدة وناتج اكسدة الدهون المالونيل ثنائي الالديهايد كمؤكسد في مرضى الصدفية ومجموعة من الاصحاء كمجموعة سيطرة في دراسة للحالات والشواهد. كما تهدف الدراسة الى التقصي عن العلاقة بين الاجهاد التاكسدي ومستويات اللبتين والرزستين فضلا عن دور هذه الاديبوكينات في توليد الاجهاد التاكسدي عند المرضى والاصحاء. المواد وطرق العمل : صممت هذه الدراسة كدراسة للحالات والشواهد. وشملت هذه الدراسة خمسين مريضا (30 ذكرا و20 انثى) مصابين بمرض الصدفية واربعين شخصا ( 20 ذكرا و20 انثى) اصحاء ظاهريا كمجموعة سيطرة بسن وجنس متوافقين. وكان متوسط العمر (45.47 ± 17.58) للذكور و(30.4 ± 19.33) للاناث لمرضى الصدفية ، وكان متوسط العمر لمجموعة السيطرة (46.35 ± 16.66) للذكور و(29.8 ± 12.25) للاناث. وقد اجريت هذه الدراسة في عيادة الامراض الجلدية في مستشفى مرجان التعليمي في مدينة الحلة، خلال الفترة من تشرين الثاني 2015 الى حزيران 2016. شخص مرضى الصدفية سريريا من قبل طبيب مختص. واجريت الاختبارات البدنية مثل مؤشر شدة مرض الصدفية ومؤشر كتلة الجسم بطرق منهجية.قدر هرموني اللبتين والرزستين بواسطة تقنية الفحص المناعي للانزيم المرتبط. وقدر الكلوتاثايون بوساطة تقنية كروماتوغرافيا السائل عالية الاداء، في حين تم تقدير القدرة الكلية لمضادات الاكسدة والمالونيل ثنائي الالديهايد بوساطة الطرق اللونية.النتائج : اظهرت نتائج الدراسة زيادة معنوية في مستويات هرموني اللبتين والرزستين والمالونيل ثنائي الالديهايد ، في حين اظهرت انخفاضا معنويا في مستويات الكلوتاثايون والقدرة الكلية لمضادات الاكسدة عند مرضى الصدفية بالمقارنة مع مجموعة السيطرة. لم يكن هناك ارتباطا معنويا بين الاديبوكينات اللبتين والرزستين مع مؤشر كتلة الجسم، بينما كان هناك ارتباطا معنويا موجبا مع مؤشر شدة مرض الصدفية. ووجدت علاقة معنوية سالبة بين الاديبوكينات ومضادات الاكسدة. في حين كانت العلاقة بين الاديبوكينات وناتج اكسدة الدهون المالونيل ثنائي الالديهايد علاقة معنوية موجبة. ووجدت ايضا العلاقات بين مؤشر شدة مرض الصدفية مع متغيرات الاجهاد التاكسدي كما هو الحال في علاقاته مع الاديبوكينات. الاستنتاجات : تقترح الدراسة الحالية شمول مرضى الصدفية بالاجهاد التاكسدي بوضوح من ملاحظة الانخفاض المعنوي في مستويات مضادات الاكسدة الكلوتاثايون والقدرة الكلية لمضادات الاكسدة والزيادة المعنوية في مستويات ناتج اكسدة الدهون المالونيل ثنائي الالديهايد، وكان ارتباط الاجهاد التاكسدي هذا ارتباطا معنويا مع شدة الصدفية.وجدت الدراسة ارتفاعا معنويا في مستويات هرموني اللبتين والرزستين في المرضى، وكان هذا الارتفاع يتناسب بشكل معنوي وطردي مع شدة مرض الصدفية. ووجدت الدراسة الحالية علاقة معنوية بين مستويات هرموني اللبتين والرزستين مع متغيرات الاجهاد التاكسدي، الامر الذي يدعم فكرة مساهمة اللبتين والرزستين في توليد الجذور الحرة والاجهاد التاكسدي في الصدفية. لذلك تقترح الدراسة ان هرموني اللبتين والرزستين قد يكونان السبب او قد يساهمان في توليد الاجهاد التاكسدي المرافق للصدفية وبعدة طرق | Psoriasis is a common skin disease affects 1 - 3% of the worldwide and is characterized by chronic inflammation of the skin epidermal cells with abnormal changes in the maturation of keratinocytes. There is accumulating evidence on the role of cytokines including adipokines such as leptin and resistin in the pathogenesis of psoriasis. On the other hand, increasing evidence was reported that psoriasis is involved in oxidative stress due to exposure of skin to reactive oxygen species, which play an important role in inflammatory responses. Objectives : The present study aims to evaluate the levels of leptin and resistin as well as, oxidative stress via measuring the levels of antioxidants, glutathione (GSH), total antioxidant capacity (TAC) and lipid peroxidation product malondialdehyde (MDA) as an oxidant in patients with psoriasis and healthy controls in case control study. The present study aims to investigate the relationship between oxidative stress and leptin and resistin levels as well as the role of these adipokines in the generation of oxidative stress in patients and healthy control.Subjects and Methods : This study was designed as a case control. Fifty patients (30 males, 20 females) with psoriasis and forty (20 males, 20 females) apparently healthy persons as control with the compatible age and sex were enrolled in this study. The mean age was (45.47±17.58) for males and (30.4±19.33) for females psoriatic patients, and the mean age for healthy control groups was (46.35±16.66) for males and (29.8±12.25) for females. The study was conducted in Dermatology Clinic of Merjan Teaching Hospital in Hilla City and Clinical Biochemistry Department in Babylon University College of Medicine during the period November 2015 to June 2016. Patients with psoriasis were diagnosis clinically by specialist physician. Physical examination like psoriasis area severity index PASI score and body mass index BMI were determined by systematic ways. Leptin and resistin adipokines were estimated by enzyme - linked immunoassay ELISA technique. GSH was estimated by high performance liquid chromatography HPLC, Whereas TAC and MDA were determined by spectrophotometic methods.Results : The results present in this study were shown as a significance increases in leptin and resistin levels as well as MDA, whereas significant decreases were found in the antioxidants levels GSH and TAC of psoriatic patients when compared with healthy control. There was no significance correlation between adipokines leptin and resistin with BMI, while there were significance positive correlations of adipokines with PASI score. The relations between adipokines and antioxidants found a significance negative correlations. Whereas, the relations between adipokines with lipid peroxidation end product MDA were significant positive correlations. Also, the disease severity as expressed by PASI score relation with oxidative stress parameters were found to be the same as that of adipokines correlations. Conclusions : The present study obviously suggested an involvement of the patients with psoriasis in oxidative stress by observing the significant decrease in TAC and GSH levels as well as the significant increase in levels of MDA, and this oxidative stress was significantly correlated with the severity of psoriasis. This study has found a significant elevation in levels of leptin and resistin in patients, and this elevation was significantly and directly proportional to the severity of the psoriasis. The current study has found a significant relationship among leptin and resistin levels with oxidative stress parameters, which supports the opinion of the contribution of leptin and resistin in the generation of free radicals and oxidative stress in psoriasis. Therefore, the present study suggested that the leptin and resistin may be the cause or may contribute in the generation of oxidative stress associated with psoriasis by many ways

دراسة لبعض الخصائص الوبائية والمصلية لاصابات الـBordetella perlussis في محافظة بابل

Author name: عمار عباس شعلان
Supervisor name: محمد عبود القرة غولي | يحيى الطفيلي
General topic: Medicine
Specific topic: Microbiology
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: تهدف هذه الدراسة الى وصف بعض الخصائص الوبائية للسعال الديكي في محافظة بابل وتقييم الاضداد المتخصصة للـ Bordetella pertussis IgG وIgA باستخدام تقنية الـ ELISA للتشخيص المختبري للسعال الديكي، هذا بالاضافة الى قياس الاستجابة المناعية الخلطية للقاح الثلاثي (DPT). جمعت عينات الدم من : 68 طفل مصاب بالسعال ديكي راقد في المستشفى (36 غير ملقح و32 ملقح) ، 103 من اشخاص اسوياء (49 شخصا ملقحا، 54 شخصا غير ملقح) و20 من العاملين بالخدمة الصحية في محافظة بابل. اضداد Bordetella pertussis IgG وIgA تم قياسها بواسطة تقنية الـ ELISA لكل مجموعات الدراسة. التعداد الكلي والتفريقي للخلايا البيضاء اجري للـ68 مريض و20 من مجموعة السيطرة. اظهرت الدراسة ان اعلى مستوى حدوث للسعال الديكي لوحظ في المرضى اقل من عمر سنة (49% من مجموع الحالات). كانت نسبة الذكور للاناث 1.27 : 1. 71% من المرضى مقيمين في المناطق الريفية مقارنة بـ 29 % في المناطق الحظرية. 36 (53%) من المرضى كانوا غير ملقحين و26 (38%) كانوا ملقحين جزئيا، بينما 6 (9%) تلقوا تلقيحا كاملا (3 جرعات من اللقاح الثلاثي). لوحظت مضاعفات السعال الديكي في 88% من المرضى، والتي كانت بصورة رئيسية الاختناق (88%)، اختلاجات (26%)، ذات الرئة (29%)، والوفاة (4%). كما لوحظ ارتفاع في تعداد الخلايا البيضاء في 64% من المرضى وارتفاع في تعداد الخلايا اللمفاوية في 69% من المرضى. معظم الحالات سجلت خلال الفترة بين شهر نيسان وتموز. كانت الحساسية والتخصص التشخيصي لاضداد الـ Bordetella pertussis IgG في الاطفال غير الملقحين كانت 77% و100% على التوالي، في حين كانت الحساسية والتخصص التشخيصي لاضداد Bordetella pertussis IgG في الاطفال الملقحين 67%، 91% على التوالي. كانت الحساسية والتخصص التشخيصي لاضداد الـ Bordetella pertussis IgA في الاطفال غير الملقحين كانت 33% و100% على التوالي، في حين كانت الحساسية والتخصص التشخيصي لاضداد Bordetella pertussis IgA في الاطفال الملقحين 72%، 86% على التوالي. لوحظت افضل حساسية وتخصص تشخيصي في العيانات التي جمعت بعد اكثر من 21 يوما بعد ظهور اعراض السعال الديكي. تم الحصول على اعلى حساسية وتخصص تشخيصي (92، 82% على التوالي) باستعمال مستوى موجب لـ اضداد Bordetella pertussis IgG او IgA. اظهرت الدراسة ان متوسط مستوى اضداد Bordetella pertussis IgG في الاسوياء الملقحين كانت 56.41 U/ml (المدى 19.77 - 143.89 U/ml)، بينما بلغ متوسط اضداد Bordetella pertussis IgG في الاسوياء غير الملقحين 29.33 U/ml (المدى 1.01 - 56.9 U/ml). كان متوسط مستوى اضداد Bordetella pertussis IgA في الاسوياء الملقحين كانت 9.05 U/ml (المدى 3.6 - 29.74 U/ml)، بينما بلغ متوسط اضداد Bordetella pertussis IgA في الاسوياء غير الملقحين 4.79 U/ml (المدى 3.05 - 7 U/ml). اظهرت الدراسة ان 10.7 % (11/103) من الاسوياء يظهرون مستوى موجب لاضداد Bordetella pertussis IgG او IgA، في حين اظهر 70% (14/20) من العاملين في الخدمة الصحية في هذه الدراسة مستوى موجب لاضداد Bordetella pertussis IgG او IgA | The aims of this study is to describe some of the epidemiological features of pertussis in Babylon Province in Iraq, and to evaluate the specific anti Bordetella pertussis IgG and IgA ELISA technique in the laboratory diagnosis of pertussis, and to determine the humoral immune response to DTP vaccine. Blood samples were obtained from the following groups : 68 (36 unvaccinated and 32 vaccinated)clinically diagnosed hospitalized pertussis patients, 103 normal healthy subject of similar age groups (49 vaccinated and 54 unvaccinated) and 20 healthcare workers in Babylon Province. The anti Bordetella pertussis IgG and IgA antibodies were tested by ELIZA technique in all study groups. The study shows that the highest incidence of pertussis was noticed in patients less than 1 year (49% of the total pertussis patients). The male to female ratio was 1.27 : 1. There were 71% of pertussis cases from rural area compared with 29% from urban area. 36 (53%) of the patients were unvaccinated and 26 (38%) of the patients were partially vaccinated, while only 6 (9%) are fully vaccinated (3 doses of DTP vaccine). Complications were noticed in (88%) of the patients; they are mainly apnea (88%), seizure (26%), pneumonia (29%), and death (4%). Most cases were noticed between March and July. The anti Bordetella pertussis IgG diagnostic sensitivity and specificity in unvaccinated subjects were 77%, 100% respectively; while in vaccinated subjects they were 67%, 91% respectively. The anti Bordetella pertussis IgA diagnostic sensitivity and specificity in unvaccinated subjects were 33%, 100% respectively, while in vaccinated subjects they were 72%, 86% respectively. The best diagnostic sensitivity and specificity was observed in samples collected after > 21 days of the onset of pertussis symptoms. The higher diagnostic sensitivity and specificity were obtained by using anti Bordetella pertussis IgG or IgA positive levels. The study shows that the anti Bordetella pertussis IgG mean level in DPT vaccinated normal subjects was 56.41 U/ml (range 19.77 - 143.89 U/ml), while it was 29.33 U/ml (range 1.01 - 56.9 U/ml) in unvaccinated subjects. The anti Bordetella pertussis IgA mean level in vaccinated normal subjects was 9.05 U/ml (range 3.6 - 29.74 U/ml), while it was 4.79 U/ml (range 3.05 - 7 U/ml) in unvaccinated subjects. There is 10.7% (11/103) of the normal subjects which have a positive anti Bordetella pertussis IgG or IgA levels. In addition, 70% (14/20) of the healthcare workers in this study have a positive anti Bordetella pertussis IgG or IgA levels.

جهد الاكسدة ومرض عوز نازعة هيدروجين الكلوكوز - 6 - فوسفات في الاطفال حديثي الولادة المصابين باليرقان == OXIDATIVE STRESS AND CLUCOSE - 6 - PHOSPHATE DEHYDROGENASE DEFICIENCY IN NEONATAL HYPERBILIRUBINEMIA

Author name: صفا وهاب عزيز
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: مرض عوز نازعة هيدروجين الكلوكوز - 6 - فوسفات يعد من الامراض المرتبطة بالاطفال المصابين باليرقان الولادي , تلف الدماغ وحتى الموت . اجريت هذه الدراسة لمعرفة ضرر الاكسدة في الاطفال المصابين باليرقان الولادي وخصوصا المصابين بمرض عوز نازعة هيدروجين الكلوكوز - 6 - فوسفات . اجريت ايضا هذه الدراسة لغرض تاكيد دور جهد الاكسدة ونظام الانزيمي المضاد للاكسدة في الاطفال المصابين باليرقان الولادي في مستشفى بابل التعليمي للنسائية والاطفال في بابل . خلال هذه الدراسة الممتدة من كانون الثاني 2008 الى الثلاثين من شهر حزيران 2008 , تم اختيار 225 طفلا مصابا بيرقان ولادي (145 ذكور و80 اناث) غير معروف السبب و50 طفلا حديثي الولادة طبيعيين (35 ذكور و15 اناث) . الاطفال المصابين باليرقان الولادي تم تقسيمهم الى اطفال مصابين بنقص انزيم عوز نازعة الهيدروجين الكلوكوز - 6 - فوسفات (المجموعة الاولى) واطفال مصابين بيرقان ولادي لكن ليس لديهم نقص في الانزيم اعلاه (المجموعة الثانية) وتم فحصهم بطريقة الاختزالية وطريقة الفقاعة المتفلورة لمعرفة عدد المصابين بنقص هذا الانزيم . لقد تبين من النتائج المحصلة في هذا البحث ان الاطفال المصابين بنقص الانزيم اعلاه هم 20 طفل (8.9 %) , 15 (75%) منهم كانوا ذكورا و5(25%) كانوا اناثا ونسبة الذكورالى الاناث هي 3 : 1 . كل الاطفال المصابين باليرقان الولادي كانوا بحاجة للعلاج الضوئي اما 14 (70%) من الاطفال المصابين بنقص الانزيم احتاجوا الى عملية تبديل كامل للدم . 2(10%) من الاطفال المصابين بنقص الانزيم كانت لديهم علامات تلف بالدماغ عند وصولهم للمستشفى وقد توفوا قبل اجراء عملية تبديل دم لهم . لا يوجد تاريخ ايجابي لتناول الادوية المحفزة لهذا المرض او تناول الباقلاء . تم دراسة عوامل دموية في الاطفال حديثي الولادة في كل المجاميع وتضمنت Hb and PCV , reticulocyte Count , WBC count . لقد تبين من هذه الدراسة وجود زيادة معنوية في reticulocyte and WBC count . لقد تبين ايضا من هذه الدراسة وجود نقصان معنوي في وزن الاطفال المصابين باليرقان الولادي وخصوصا الذين يعانون من نقص الانزيم اعلاه مقارنة مع الاطفال الطبيعيين (P value < 0.05) . ان نقص الانزيم يمكن ان يؤدي الى زيادة خطر اليرقان الولادي . هذه الدراسة دلت على وجود زيادة معنوية في مستوى مالون داي الديهايد (MDA) في الاطفال المصابين باليرقان الولادي والاطفال المصابين بنقص الانزيم (P value < 0.05) بينما نقصان معنوي في مستوى كلوتاثايون (GSH) وفعالية انزيم الكيتيليز (CAT) عندما قورنت مع الاطفال الطبيعيين (P value < 0.05) . وجد ايضا علاقة موجبة بين TSB وMDA وكذلك بين GSH وHb بينما هناك علاقة سالبة بين TSB مع GSH CAT , وHb وكذلك بين MD وكلا من GSHو CAT . | Glucose - 6 - phosphate dehydrogenase deficiency is the most common enzymopathy associated with neonatal hyperbilirubinemia , kernicterus and even death . This study was conducted to know oxidative damage in neonates with neonatal hyperbilirubinemia and G6PD deficiency . Also this study was conducted to detect the role of oxidative stress and antioxidant enzymatic system in neonatal hemolytic jaundice of Babylon Maternity and Children Teaching Hospital . A prospective study was conducted during the period from 1st of January 2008 to the 30th of June 2008 in Babylon hospital of Maternity and Pediatric . Over the study period , a total of 225 full - term newborn infants with neonatal hyperbilirubinemia (145 males and 80 females) and 50 healthy neonates taken as a control group (35 males and 15 females) were studied . Newborns with hyperbilirubinemia were subdivided into G6PD deficiency (I group) and normal G6PD (II group) , a reduction method test and fluorescent spot test were used to assay the activity of G6PD . In this study , 20 (8.9%) of neonates with hyperbilirubinemia had G6PD deficiency . Fifteen (75%) of the G6PD deficient patients were males and 5 (25%) were females with male : female ratio 3 : 1 . In both normal and G6PD deficient (II and I) , reticulocyte counts and WBC were increased while PCV and Hb were decreased when compared with control group . There was a significant decrease in weight in normal and G6PD deficient groups when compared with control group . G6PD deficiency was led to increase risk of neonatal hyperbilirubinemia with significant number of them which required exchange blood transfusion 14 (70%) . All neonates with hyperbilirubinemia have received phototherapy . Two neonates (10%) with G6PD deficiency were presented with kernicterus signs and both of them died . The present study indicates significant increase in malondialdehyde (MDA) level of neonates with hyperbilirubinemia and G6PD deficiency when compared with the control group . A significant decrease in serum catalase (CAT) activity and glutathione (GSH) in neonates with hyperbilirubinemia and G6PD deficiency was found . There was positive correlation between TSB and MDA , GSH and Hb . There was a negative correlation between TSB with GSH , CAT and Hb and between MDA with GSH and CAT .

دراسة فعالية نبات عين البزون كعلاج طبيعي لمرض سرطان الدم المستحث في ذكور الفئران == Study the Activity of Catharanthus Roseus as Natural Treatment for Induced Leukemia in Male Mice

Author name: محمد عبود عياش
Supervisor name: مفيد جليل عوض | نسرين جلال محمد
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: Leukemia is cancer of blood - forming tissues, begin in the bone marrow characterized by highly elevated of abnormal proliferation and circulation of immature clonal hematopoietic cells. It can affect all ages around the world which in turn considered as one of public health problem.Plants considered as an important source for medical drugs manufacturing due to the presence of certain compounds with medicinal biological activity, therefore adopted in the preparation of a lot of medicines and medical drugs because of its' speed therapeutic influence and low of negative side effects which caused by chemically manufactured medications.The present study aimed to evaluate the activity and efficiency of vincristine and other important constituent in Catharanthus Roseus plant in treatment of leukemia through enhance and direct impact on some of the body's vital biological activities by using fresh crude plant as herbal medicine. This study is Cohort study design. It is monitoring, detection, and investigation study that included some of groups that completely under control; this study used in medicine, nursing, psychology and social sciences in addition to the Ecology. This study included (60) Albino male mice divided into four groups (15) mice for each. Group (A) was the control group, group (B) was mice feed orally with of C. Roseus plant, group (C) was leukemia induced mice by subcutaneous injection of (300mg/kg B.W benzene), and group (D) was Induced leukemia mice treated by oral feeding with C. Roseus plant. The experimental work was carried out in Clinical Biochemistry Department / College of Medicine / University of Babylon during the period from (October 2015 to August 2016).High - Performance Liquid Chromatography (HPLC) technique was used for measurement of Vincristine drug (VCR) in plant and vitamin D levels in mices' serum, Enzyme Linked Immunosorbent Assay (ELISA) had was used for the measurement of serum ferritin, UV - Vis Spectrophotometer was used for determination of GSH - Px and GST concentrations, while Graphite Furnace Atomic Absorption Spectrophotometer technique (GFAAS) was used for measurement of trace elements concentration of (Fe, Cu, Zn, Se). There were hematological and histopathology studies carried out by using special required equipment to make sure that leukemia disease was indeed occur.Hematological study included measurement of Hb levels and WBC count, while histopathology study included bone marrow, liver, kidney, spleen smear. Microscopic investigation for Chromosomal Aberration and Micronuclei were also had been done.Results showed that C. Roseus plant contain the concentration of vincristine drug up to 148μg/gm. There was highly significant increase of serum ferritin levels, GST activity, Iron and Copper concentration, and WBCs in leukemic group (C) (P<0.001) when compared with control group (A), while there were highly significant decrease of these parameters in group (B) as compared with the control (A) and (C) groups.Results also showed a highly significant decrease of GSH - Px activity, Vit.D levels, Zinc and Selenium concentration, and Hemoglobin levels in group (C) (P<0.001) when compared with the control group, while there were highly significant increase of these parameters in group (B) as compared with control and (C) groups. The present study found a positive correlation between Vit.D and GSH - Px activity, Ferritin and GST activity, while this study found a negative correlation between Ferritin and GSH - Px activity, serum Iron and Selenium concentration.The present study found positive effect of C.Roseus on abnormal parameters and support the biological system which was clear in group (D) which demonstrated that there were significant inhibitions to decrease or increase of these parameters than those in healthy control.

الحقوق السياسية لمتعددي الجنسية == Political Rights For Multinationals

Author name: روافد محمد علي الطيار
Supervisor name: علي هادي حميدي الشكراوي | فراس كريم شيعان
General topic: Law
Specific topic: Private International Law
Degree: Doctorate
Language: Arabic
University location: Babylon
First pages:
Abstract: The contribution of the individual in political life is based on a fundamental requisite to enjoy the nationality of the State which purports to exercise their political rights on its territory, but that he may enjoy the individual more than the nationali

الحماية الجنائية للاطباء : دراسة مقارنة == The Criminal Protection For Doctors A Comparative Study

Author name: نسرين محسن نعمة الحسيني
Supervisor name: علي حمزة عسل الخفاجي
General topic: Law
Specific topic: Criminal Law
Degree: Doctorate
Language: Arabic
University location: Babylon
First pages:
Abstract: الحماية الجنائية للاطباء تتمثل بالنصوص التي يقررها المشرع الجنائي لاحاطة الاطباء بالحماية التي يراها كفيلة برد الاعتداءات والافعال غير المشروعة التي قد تؤدي الى النيل من حياتهم او سلامتهم الجسدية او شرفهم وذلك بتجريم كل من يعتدي عليهم ومعاقبته والاقتصاص م | The Criminal Protection for Doctors (A comparative Study)Criminal protection for physicians are texts decided by the criminal legislator to inform doctors the protection seen enough to chill all kinds of attacks and illegal acts that may lead to the Nile

التوفيق بين احكام التجريم والعقاب وثوابت احكام الاسلام : دراسة مقارنة == Matching Between Rules of Criminalization And Penalization And Constants of Islamic Rules Comparison Study

Author name: حيدر حسين علي الكريطي
Supervisor name: حسون عبيد هجيج
General topic: Law
Specific topic: Criminal Law
Degree: Doctorate
Language: Arabic
University location: Babylon
First pages:
Abstract: تعالج الاطروحة مشكلة دقيقة ومعقدة متشعبة الجوانب ومتعددة المستويات تتمثل بتعارض احكام جوهرية اساسية يضمها التشريع الجنائي العراقي مع القاعدة الدستورية المحورية التي رسخها دستور جمهورية العراق لعام 2005 وهي : ( عدم جواز سن قانون يتعارض مع ثوابت احكام الاسل | This study tackles with a minuet, complex and ramified - sides problem with multi levels are represented by conflicting of major essential laws included by Iraqi criminal legislation with the constitutional central base that was installed by the Iraqi con

اثر الحكم الصادر بعدم الدستورية : دراسة مقارنة == The Effects of The Judgment of Unconstitutionality Comparative Study

Author name: احمد علي عبود الخفاجي
Supervisor name: رافع خضر صالح شبر
General topic: Law
Specific topic: Constitutional Law
Degree: Doctorate
Language: Arabic
University location: Babylon
First pages:
Abstract: The constitutional judiciary controls laws with a view to ensure respect for the rules in the constitutional document of the most important legal means to ensure enforcement of the law and properly implemented, they are designed to safeguard the constitut

الجرائم ضد الانسانية في ضوء احكام القانون الدولي : دراسة مقارنة == Crimes Against Humanity In The Light of The Provisions of International Law A Comparative Study

Author name: جواد كاظم طراد الصريفي
Supervisor name: حيدر كاظم عبد علي | حسن عودة زعال
General topic: Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: ان ظاهرة الجريمة ليست ظاهرة حديثة, اذ انها وجدت منذ وجود الانسان على الارض, وما قتل قابيل لاخيه هابيل الا دليلا على ذلك, ومنذ ذلك الحين والى يومنا هذا تشهد البشرية انواعا كثيرة جدا من الجرائم, ومن اهم تلك الجرائم واشدها خطورة على الامن والسلم العا | the phenomenon of crime is not modern phenomenon, since it is found on the ground since the existence of human, and killed his brother Qabil Habil but proof of this, since then and to this day mankind is very many types of crimes, it is most important tha

النظام القانوني لعقد خدمات الهاتف المحمول : دراسة مقارنة == Legal System For Contract Carried Phone Services Comparative

Author name: كاظم فخري علي الخفاجي
Supervisor name: اسيل باقر جاسم
General topic: Law
Specific topic: Civil Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Led developments technological modern in the field of communications, especially in the field of wireless communications to the emergence of new ways used in the performance of these services and the emergence of mobile phone services has led to the emerg

النظام القانوني للمفاوضات في عقود التجارة الدولية : دراسة مقارنة == System Legal Status of The Negotiations In International Trade Contract A Comparative Study

Author name: استبرق محمد حمزة محسن
Supervisor name: ذكرى محمد حسين الياسين
General topic: Law
Specific topic: International Criminal Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Negotiations in the contract of international trade is a preparatory phase that has conducted talks and discussions between the parties wishing to contract by developing specific proposals and clear in order to reach agreement to its conclusion, The contr

الاختصاص التشريعي في الدولة الاتحادية : دراسة مقارنة == The Legislature Jurisdiction In Federal State Comparative Study

Author name: وليد حسن حميد الزيادي
Supervisor name: رافع خضر صالح شبر
General topic: Law
Specific topic: Constitutional Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: It is well known that the most important characteristics of the federal State is bilateral political power or duplication, so that there are two types of power, the first is the federal authority and the second is the authority of the constituent units of

النظام القانوني للهيئات المستقلة : دراسة مقارنة == The Legal System To Independent Bodies Comparative Study

Author name: صادق محمد علي الحسيني
Supervisor name: اسماعيل صعصاع غيدان البديري
General topic: Law
Specific topic: Constitutional Law
Degree: Doctorate
Language: Arabic
University location: Babylon
First pages:
Abstract: The idea of independent bodies, which prevailed in many of modern legal systems, considered as modern concept. however the purpose of establish its in order to achieve most important functions deals with public freedom, economic action or transparency as

حرية الموظف العام في التوقف عن العمل : دراسة مقارنة == The Freedom of Public Employee To Stop Working Comparative Study

Author name: اسماء عبد الكاظم مهدي العجيلي
Supervisor name: اسماعيل صعصاع غيدان البديري
General topic: Law
Specific topic: Administrative Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The public employee is the tool of the state to perform its vary tasks, it is impossible to imagine an existing of state without the human ingredients those work and manage the public facilities.Hence, the public employee must have some freedom to pract

الحق في حرية التظاهر السلمي : دراسة مقارنة == The Right To Freedom of Pacefic Demonstraion Comparative Study

Author name: اركان عباس حمزة الخفاجي
Supervisor name: علي هادي حميدي الشكراوي
General topic: Law
Specific topic: Constitutional Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Freedom of peaceful protest become in now days one of publicfreedom which has significant importance on individual and society level,and it no longer consider - at least in Arabic society - one of hard to gainfor native.it become approachable because o

الحماية الدولية للقائمين بالخدمات الانسانية اثناء النزاعات المسلحة == The International Protection For The People Who Are Dedicated For Humanitarian Tasks During The Armed Conflicts

Author name: احمد رحيم خضر
Supervisor name: طيبة جواد حمد المختار
General topic: Law
Specific topic: Constitutional Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: In its stages of the long history, the humanity witnessed wars which had disastrous effects on the innocent people. Since the beginning of history, the war is the event that accompanies the human beings in their time. Fierce wars have been taken place - s

حدود حل البرلمان : دراسة مقارنة == Restriction of The Parliament‘S Dissolve Comparative Study

Author name: علي سعد عمران
Supervisor name: رافع خضر صالح شبر
General topic: Law
Specific topic: Constitutional Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Every Act would done by a person, whether a natural, moralperson must be organized in a manner consistent with thesubject matter of the act on the legal relationship of the partieswhich may affect this act. Perhaps this is the legal organizationof the

الرقابة الادارية للمفتش العام على عقد الاشغال العامة في العراق == The Administrative Inspection For Public Inspector on Contract of General Works In Iraq

Author name: عبد الحسين عبد نور هادي الجبوري
Supervisor name: اسماعيل صعصاع غيدان البديري
General topic: Law
Specific topic: Constitutional Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The administrative inspection for the general inspectors offices on the contract of general works occupies more importance which taken from the aims to be achieved the inspection can be found in every rule of the constitution that draws the public from an

الحماية الجنائية لحقوق المواطنة السياسية : دراسة مقارنة == The Criminal Protection of Political Citizenship Rights : Comparative Study

Author name: عباس كاظم خطاب الربيعي
Supervisor name: لمى عامر محمود
General topic: Law
Specific topic: Criminal Law
Degree: Master
Language: Arabic
University location: Babylon
Abstract: تعد الحماية الجنائية واحدة من اهم صور الحماية المقررة لمختلف الحقوق وخاصة حقوق المواطنة السياسية, اذ تعد الحقوق محل البحث من اهم الحقوق التي تمنح للمواطن دون الاجانب عكس الحقوق المدنية والاقتصادية والثقافية الخ, حيث قد تمنح تلك الحقوق للمواطنين والاجانب | An individual in state has many rights; civil, social, economic, cultural and political rights. But the political rights are given a special interest, and must be arranged by local legislations, especially criminal legislations. The nationality is criter

استرداد المتهمين والمحكوم عليهم في جرائم الفساد == Recovery of The Accused And Convicted of Crimes of Corruption

Author name: حسين معن ابراهيم
Supervisor name: فخري عبد الرزاق صلبي الحديثي
General topic: Law
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تعد الجريمة اھم ما يھدد الكيان الاجتماعي للدولة، لذلك فان الدول تحاول في قوانينھا واجراءاتھا الحد منھا من خلال معاقبة فاعليھا ومنع الاخرين من اقتراف السلوك الاجرامي، وفي الاونة الاخيرة تفشت انواع من الجرائم وھي جرائم الفساد الاداري والمالي على نطاق واسع و

الهبات والهدايا عند ائمة اهل البيت عليهم السلام == Donations And Gifts Of The Prophet Progeny (Ahlul Bait ) God'S Peace Be Upon Them

Author name: الهام عبد الواحد ناجي
Supervisor name: زينب فاضل رزوقي مرجان
General topic: History
Specific topic: Islamic History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Donations and Gifts of the Prophet Progeny (Ahlul Bait ) God's peace be upon them "Praise be to Allah , Peace be on the elite of creatures " Prophet Mohammed and his Folk ".The speech about the Imams of Prophet Progeny " God's be upon them " is most fine speech and most fresh Biography ( Seerah) , they are the ideal devoted for Islamic nation to Good and direction ,therefore the offering of donation and gifts was an important factor of their noble social conduct that made them reach the most generous levels.The significance of subject is related by Imams of Prophet Progeny as what they represent of moral effect in Muslims spirits and for augustness rank that Holy Quran and Prophet's route had make reference to.No doubt that the develop of this nation is depend on how much it follow the way of life for Prophet Progeny and their instructions which is the instructions of their Grandfathers the Prophet Mohammed ( God's peace be upon him and his folk ) and it is the Instructions of Mighty Allah.Prophet Progeny were famous that they share people with what the people were suffering of agony and needs , so generosity is one of their Character that represented by Donations and Gifts that they gave. they were targeting the satisfy of Mighty Allah in this deeds , those donations and gifts in many times were lead to help the people who they in bad need for assistance or even to bring back the persons for direction route. Each gift or donation that Prophet Progeny were gave it shows a moral lesson , wise or exhortation that enable us to discipline ourselves for our good return in life and doomsday. Prophet Progeny were an owner of money and property , they spend those money and properties for the benefit of poor people just to seek Allah satisfaction. They had a great role of work in agriculture and trade and they emphasis through their speech on sedulity and avoid laziness due to work is reserve human dignity , also they emphasis on help beggar and respect his dignity and not reject his demand. Opportunity and Situations of offer that donations and gifts by Prophet Progeny are varied some of those gifts were for help poor ,needy people and traveller ,also it offer to encounter offense by humanism and to discharge of a debt ,and for support at disaster time and crises. Donations and gifts were offered in a manner scientific reward or for particular services.Poets has a share of Prophet Progeny gifts with appreciation and respect due to they adhere to principles of Imams (Gods peace be upon them ) and convey their virtues and explain their calamity. on other hand many of Jews and Christian embrace Islam by the Imams of Prophets Progeny due to what they found in them of good manners ,sciences they have and their religious. Prophets Progeny participated in enfranchisement of slaves and that after purchase them and taught them the Islamic Culture then enfranchise them for sake of Mighty Allah. The Imams of Prophet Progeny didn’t hesitate in provide moral support that is represented by advices and instruction for the Umayyad and Abbasian rulers at the time of crises for the Benefit of Islamic State, in spite of the oppression and persecution of those rulers against Imams of Prophet Progeny. The nature of Researcher requires to divide the subject into Introduction ,prelusion ,three chapters and conclusion : First Chapter deals with pecuniary Donations and Gifts that Imams of Prophet Progeny offered in different opportunities , while Second Chapter is in title of Donations and Gifts in kind that Imams offered like : property , enfranchisement , foods , clothes , jewels and perfume and much more.Third Chapter includes Donations and Gifts ( Pecuniary - in kind) and ethical , ethical gift represents by Kind words and Advice and granting Science and supplication , so they were exactly as their Grandfather The Prophet Mohamed (Allah Peace be upon them) if any one comes to the prophet to ask a need , the prophet wouldn’t reject him ever and wouldn’t made him return without his needs or with feasible of speech. We ask and pray to Mighty Allah to make us adhere to Imams of Prophet Progeny and we also pay to Mighty Allah to make us firms on their route by word and deed , May Mighty Allah respond to our pray
Summary:
References:

التوحيد الديني عند العرب قبل الاسلام : دراسة تاريخية في الديانة الحنيفية وعبادة الرحمن == Monotheism At Arab Nation Before The Islamic (And To Study The Arthdox And Worship The God Merciful)

Author name: صلاح غلام غضيب العوادي
Supervisor name: عبد الخضر جاسم حمادي
General topic: History
Specific topic: Arab History Before Islam
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The researcher had reach in his thesis (A consideration the single God at Arab nation before Islamic moment. I study Orthodox and belief in God the merciful ) the human being needs to religion. It gives him the rest in dogma and spiritual believing. It is in origin of human. Where as the Arabic man closed with his religion and conduct the worship , adoration therefor IBRAHIM and come to correct this consideration (peas upon him) to guide for faith and make correction the religions at that time. But it continue it established to them new rules and now dogma established the monotheism. To the orthodox nation. The researcher explained the terms of monotheism and worship of God only that was mention in wholly Quraan in several terms. As long as appeared some different religion in the Jewish and and Christian also ALSHBIAA and other kinds of religion. But all these kinds of religion didn`t affect on the monotheism in the Arab land and it became the way to express Arabic nation self to search orthodox religion and to worship God and related strongly with calling IBRAHIM peas upon. The significant of this thesis (Monotheism of Arabic man before the Islamic study in orthodox and worship God the merciful) that is the relation between worship of god and orthodox religion, that all these time consideration are represented the monotheism dogma.This thesis divided to three chapters : The first - meaning of Monotheism and the logical meaning in Quraan and history.Includes three parts (A) meaning of monotheism and the indication of language.(B) consideration of Quraan about the monotheism that to show the script of some terms in Quraan.(C) As historical religions consideration of the Arab and the heaven resources where as relation with IBRAHIM peas upon him.The second chapter it speaks about the monotheism and people who belief in this dogma. But the third chapter which is search with worship God merciful and mentioned on the old written and historical and Islamic resources and in general literature. The thesis and by summary about monotheism before Islamic movement
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اثر الموالي في الحياة الفكرية في بغداد من خلال كتاب تاريخ بغداد للخطيب البغدادي ت 463هـ/1070م == Pro In The Intellectual Life In Baghdad During The Impact Of The Book On The History Of The Baghdad Khatib Al - Baghdadi (D. 463 AH / 1070 AD)

Author name: سرى سلام عطية الابراهيمي
Supervisor name: عبد الستار نصيف جاسم العامري
General topic: History
Specific topic: Islamic History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: After it was founded in the city of Baghdad (145 - 146 AH / 762 - 663 AD) became this city a prominent role in the intellectual life became not only in the Muslim world but also in the whole world known in that era course science, it worked to attract scientists from different religions and countries for reasons of scientific, social and other political and economic. The importance of the study of the subject of the importance of the history book of Baghdad, which includes translations of Arab and pro - eating male genealogy and scientific journeys and their elders and their pupils and their works, and the fact that Baghdad was the capital has become a pilgrimage site for students of science and of them pro who was the offspring intellectual apparently comparable to the product of the Arab Muslims has contributed to supplement Islamic Arab libraries and for this reason that prompted Balbagesh Valley midst of their search for pro in Baghdad through the history book of the Baghdad Khatib al - Baghdadi. The letter came on the unprecedented three chapters with an introduction and followed by a conclusion and supplements and a list of sources and references. The first chapter, entitled (life - Khatib al - Baghdadi, social, scientific and factors that contributed to attracting loyal to Baghdad) has included a brief introduction about his social and scientific existence of several studies leading up about that, and also ensure that the factors that contributed to attracting loyal to Baghdad. The second chapter was titled (per pro in religious studies) included Quranic science of knowledge of interpretation and readings also included modern science and jurisprudence. The third chapter is entitled (per pro in the humanities and sciences Pure "Applied") was developed humanities and sciences Pure "Applied" and anyone to separate in order to balance the message and the reason for this is the limited number of these translations for them in pure science compared to religious sciences and humanities and mentioned in this chapter pro in language and grammar, poetry and prose branches of public speaking and writing the role, and we dealt with stated theology, mysticism and science of history, either pure science Vtnolna scientists from pro in Science said the account included Conclusion prominent our findings through what provides us the information. the most prominent the significance of the date in Baghdad said translations and pro about the social and intellectual life, and the study proved that the pro was their contribution is clear and prominent in the intellectual life and measured the number of intellectual works that have contributed to supplement the Arab Islamic libraries
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مصالي الحاج ودوره السياسي في الجزائر حتى عام 1974م == Messali Al Hadj And His Political Role In Algeria Until 1974

Author name: رنده زيدان خليف رشيد النعيمي
Supervisor name: يحيى كاظم حمود المعموري
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Algeria, which is one of the Arab Maghreb countries, was under French occupation in 1830 after forcing Ottoman occupation out, to become its replacement. National figures, such as Messali Hadj (1898 - 1974), worked hard to establish fronts, groupings, and blocs to challenge the new occupation which tried to Frenchify Algeria. Algerian historians disagreed about this figure, where some of them considered him as obedient to French occupation and accused him of treason while others considered him as a nationalist who struggled through following peaceful methods and international channels to submit the Algerian problem in order to stop or reduce bloodshed. Therefore, this difference about Messali Hadj resulted in different political situations which led to this confusion in general considerations about this figure. In this study, we put the lights on the character of Messali Hadj and we found that he was one of the nationalists who tried to convey his thoughts to get occupation out of the country without using armed force and by peaceful methods. Eventually, he convinced that it is necessary to use force. As a result of existing conflicts between those who stood up to liberate Algeria, he retired from political action, and yet he didn’t participate in the revolution of 1954 which granted Algeria full independence. Through examining the course of events, we found that the results reached by the researcher are : 1 - Messali Hadj is one of Algerian nationalists who affected the Algerian history and spent most of his live in struggle and resisting French occupation. 2 - National movements appeared in Algeria through national and religious figures after second world war and after returning most of young recruits to the country. 3 - Messali Hadj took part in establishing a party which succeeded in north Africa, where he was one of its founding members and hold leadership of the party in 1927. 4 - Messali Hadj was well known for his national spirit through his enthusiastic speeches for Algerian people or in the international forums. However he followed peaceful methods to present claims of Algerian people and achieve them. So, he decided to seek with all of his strength to submit claims of Algerian people in League of Nations and other conferences which were held to make reconciliation between the occupation and people of Algeria in a way that illustrate the sufferings of Algerians
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الرواية التاريخية في كتاب العقوبات لابن ابي الدنيا (ت281هـ/894م) == The Historical Narrationsin Alukuba'At Book By : Ibn Abi Al - Dunya(281 - 894 H)

Author name: فلاح حسن عباس
Supervisor name: عبد الستار نصيف جاسم العامري
General topic: History
Specific topic: Islamic History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: All praise is to Allah, the Lord of the worlds and His blessings and peace upon his prophet Muhammad and his Descendants (Ahl al - Bayt). The study of "Alukuba'at Book" ( Divine Miracle Punishments) written by Ibn Abi al - Dunya is one of the significant matters in religious Islamic History. Ibn Abi al - Dunya's full name is Abdullah bin Muhammad Bin Ubaid Bin Sufyan Bin Qais, Alqurashi,.He was born in 208 H/823 A.D in Baghdad and died there(Jumada Al - Ula) in 281H/894 A.D. He is considered one of the best learned and highly respected religion teachers, (deeply spiritual man) historians and narrators in the Third Hijri Century. His contributions are wide - spread in various fields of knowledge. His wide mentality and vast thinking are distinguished. This is very vivid in his productions(books) which some of them printed and others not yet. Although he was a freedman of the Umayyads, he became the tutor of several ?Abb?sid princes and in particular of those who were later to become caliphs as al - Mu?ta?id and al - Mu?taf? because of his intelligence and fame. Ibn Abi al - Dunya's father was a man of wisdom and Hadith narrator. He taught his son (Ibn Abi al - Dunya) and supported his progress from an earlier time. Ibn Abi al - Dunya contributed in The reformation movement of the community through his writings and classifications. He wrote many books in education and piety and continued teaching generations until his death at the age of seventy on Tuesday 14th of Jumadi 281 H/894A.D. Ibn Abi Al - Dunya was a man of moderation and neutralism between the sects in his religion(Muslims). So, he combined and comprised all sects. For examples, he wrote about Ahl al - Bayt (Prophet Muhammad's representatives) , and composed many books like; "Al - Awlia" (Faithful) and their virtues, "The Virtues of Imam Ali", "The death of Imam Ali", "The Marriage of Lady Fatima", "The Death of Imam Hussein", "Ashuraa", " The Telling of Lewis Al - Qurrani" and " The Death of Ibin Ju'bair" and others. This neutralism and fairness what has made me to select this personality because we (at this present time) are in an urgent need to such a person not to encourage extremism and terrorism. In my research paper, I have focused on Ibin Abi Al - Dunya of being historian rather than social counselor or religious educator. I have chosen his book "Alukuba'at Book" ( Divine Miracles and Punishments) a field of may study for what it contains so much history narrations (Stories) of nations (The People and their Prophets) of what happened to them. These nations disobeyed their Creator (Allah) and forged His Sharia (Divine Laws). I have organized this paper into four chapters with an index and the resources. The first section of the first chapter focuses on the background of Ibn Abi Al - Dunya, his name, birth, full name, surname, early growth (education), religious sect and his death. The second section handles his life, masters(teachers), students, fame, journeys and his books. The second chapter is of three sections which, of course, deals with the method and sources of the book" Alukuba'at". The first section I describe the book ,its reasons of writing, its importance, prints(copies) and its divisions. The second section is to clarify the resources Ibn Abi al - Dunya recited from which include Quran, Holy Hadith (The Prophet's speech) and other telling. The third section is about the fundamentality and method of his book (Alukuba'at), so I identified the basis of selecting his historical matters, his recitations of verses of Quran, the recitation of holy Hadiths and his personal mentality weaving these basis together. The third chapter I have dealt with the history of Hadiths (The time Hadith was narrated) in this book because it is not chronically arranged. I have rearranged them newly depends on other narrations which this chapter called 'History Stories of Prophets'. In this chapter I focused on the stories of the Prophets Adam, Abraham and Lot (PB). This chapter includes two sections. The first one is about the Story of Adam, its reasons and the heavenly punishments and the historical narrations about it. Also the story of the prophet Noah and what included of historical narrations. The second section comprises the stories of the prophets Methuselah, Heber, Abraham and Lot and their narrations. The fourth chapter is titled as 'The Historical Stories of the prophet Jacob' and also Elephant Companions and what has been revealed of Israelites. This chapter is of two sections. The first one deals with the stories of the prophets Jacob, Joseph and Jonah. The second one is about the story of the prophet Job, its history narrations and the Israelites in it.Finally, I have studied and reviewed these stories and historical narrations compared to other resources trying hard to achieve and select the most remarkable and acceptable one. In conclusion, I have deeply dealt with the best and convincing results of what I am aiming at depending on available information.
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كربلاء من 1749 - 1869 : دراسة في الاحوال السياسية والاقتصادية والاجتماعية == Karbala From 1749 - 1869 A Study In The Circumstances (Political, Economic And Social)

Author name: احمد باسم حسن الاسدي
Supervisor name: فؤاد طارق كاظم العميدي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تناولت هذه الدراسة تاريخ كربلاء في المدة 1749 - 1869 دراسة في الاحوال السياسية ولاقتصادية والاجتماعية، وكان الجانب السياسي قد تميز بمرحلتين المرحلة الاولى منذ عام 1749 - 1802 وفيها تمتعت مدينة كربلاء بالاستقرار السياسي والامني النسبي، وتبين ان لذلك تاثير ايجا | This study takes the history of Karbala in the period 1749 - 1869, a study in the political, economic and social conditions, and it was the political side has been marked by two phases the first phase since 1749 - 1802 which the city of Karbala enjoyed the political and the security stability relatively, showing a positive impact on the overall economic, social and intellectual life. The second began with Wahhabi attack in 1802, and the subsequent attacks that have caused insecurity in most of Iraq's border towns on the West, including Karbala, then Daood Pasha attack on Karbala until the end of the Mamluk era. Karbala was also attacked in the subsequent period by the governor of Baghdad Najib Pasha in 1843. Karbala witnessed a chaos in its security in 1757 when the people of Karbala revolted against conscription.the study in the second chapter went to the economic conditions in Karbala, and we dealt agriculture in the forefront and land and factors affecting the production, then we talked about industry and industrial trades in the countryside of Karbala, in the city we found that the industry was primitive and in the rest of the state of Baghdad and surrounded lands. the industry was dependent on raw materials available in the city like clay and palm wood or Aromated, then the study took the trade in Karbala so we mentioned roads, transport and the markets in Karbala, and means of trade coins, and incomes of the city and of the visitors and fee of funeral and etc. The third chapter we took the social conditions in Karbala starting with the urban planning for the city of Karbala, then Karbalai society and aspects of social life in the city and the countryside and the most important families who live in the city of Karbala and the clans that live on the outskirts of the city and mutual influence between them, and we took the social aspects at the community in the city and the rural community. and there is no doubt that the relationship was overlapping between them and even social manifestations are similar to a large extent, because the city's community is an extension of the community rural, As for social services. In fact, it has been non - existent for them, there are no hospitals, no schools, no doctors, no teachers, which led to the spread of ignorance that has led to the spread of diseases that Karbalai community suffered a lot. The fourth chapter contained the scientific movement in Karbala that have flourished since the mid - eighth century, and was the most prominent scholars of Karbala at that time is the religion leader Mohammed Baqer Al - Behbahani. During this period scientific schools spread, libraries, government offices and mosques. Scientific movement has been accompanied by the emergence of different religious mobilizations affected the fundamentalist religion that came into conflict with them, including the news and then Shaykhiyyah, scout and then Babiah which is the most dangerous thing that faced fundamentalist religion but it’s survived thanks to the efforts of fundamentalists scientists. As well as the cultural movement flourished and a number of poets were appeared, it is worth to mention that the scientific movement was influenced by the political situation and turned out to be that the period of political stability accompanied by scientific prosperity which became weak in the nineteenth century because of the Wahhabi attacks as well as the political turmoil that accompanied the attack of Daoud Pasha on Karbala and the subsequent as the attack of Najib Pasha. But in spite of that we should realize that Karbala was enjoying a scientific prosperity in the next period thanks to the presence of a number of scientists.
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العلاقات الالمانية - الروسية (1870 - 1914) == Germany - Russian Relations 1870 - 1914

Author name: نادية جاسم كاظم علي الشمري
Supervisor name: علي هادي عباس المهداوي
General topic: History
Degree: Doctorate
Language: Arabic
University location: Babylon
First pages:
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تطورات التعليم في الكويت 1946 - 1971 == Developments Of Education In Kuwait 1946 - 1971

Author name: عائد مجيد عبد زيد العيساوي
Supervisor name: احمد يونس زويد الجشعمي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The education of Kuwait has developed between 1946 - 1971 for many reasons that participated in this development, the geographical position and the trade with foreign countries , this has increased the relationship between the Kuwaiti people and tradesmen , so the idea of education created selecting the best educated people of Kuwait that are working in the trade field and by the help of capitalists and tradesmen by holding their accounts , also the help of mosques and small libraries that specialized in religion education to create people who know how to read so it became easy to teach them how to write by founding semi governmental schools by Al - Mubarakiya school , plus the founding of literature club that supported the students materially and spiritually and offered all their necessary needs that helped in supporting the education and the number of students , also the stable politician situation that happens in Kuwait after the stable ruling of Al - Sabah family that supported the education since 1921 ,and formed by founding the Al - Ahmadiyah school materially and spiritually so the governmental education emerged so as to the governmental schools that took the Egyptian and Iraqi curriculum , that supplied the society by local education energies , all that resulted in education cooperation between Kuwait and the rest of the world countries , because of the scholarships Kuwait offered its students outside its borders and the bursaries that offered to Arabian and the province students , that helped in developing the education of Kuwait , by contacting the different cultures of the countries that the scholarships have been sent to Kuwait helped other Arabian countries that helped in developing their education , the education in Kuwait did not stay at the elementary and high schools ,but it reached to creating the Kuwait University in 1966 and the graduation of different specializations in 1970.
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تطورات التعليم في البحرين (1961 - 1981) == Education In Bahrain Developments (1981 - 1961)

Author name: حسين نعمة محمد الخفاجي
Supervisor name: مشتاق طالب حسين الخفاجي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Education is one of the basic factors that contribute to building societies, politically, socially, economically and culturally, so the Bahraini government has paid education much attention, especially after that I realized that investing in people is the best investment in the long run, as I realized that the power of education, cohesion and planning and development helps in the development of society, and even help to the renaissance of the state and its development, hence the importance of the subject and the motivation to study it. Despite the importance of the subject and privacy, but that academic studies omitted searched historically and disclosure of mastery, and as the Bahrain are part of the Arab system in general and the Gulf in particular, and as the search in the partial problem contributes greatly to the development of treatments for similar problems in them, so the study came to contribute to shed light on this issue to achieve the desired objective and above, but it is a motive to search. Therefore, this study was entitled to (education developments in Bahrain 1961 1981), to search for the cause of the development of education in Bahrain during the years in question, being of privacy in the history of Bahrain in general and the history of education in particular the years. As education witnessed in these years a remarkable development since 1961, due to the attention of the Emir of Bahrain Sheikh (Isa Bin Salman Al - Khalifa) and his education, he has established in his reign, many schools, colleges and universities, has sent missions to the study, and encouraged talented and gifted in a ceremony to be held for them in every year b (science festival) as grant awards for science and his students. We finished the study and up to 1981 for the accession of Bahrain, the Gulf Cooperation Council, since its accession there have become common policies in several areas with the countries that participated in this cooperation, including education.By tracking the development of education in Bahrain in the years 1961 1981 can devise a set of results, most notably : 1 - early education began in Bahrain early, marked by religious education Ketatibi, as it was the boys and girls memorized the Koran and the Sunnah and learn to read and write by the mullahs and writers who Qsteke to receive lessons. It was natural blossoming of this type of education as a result of religious factors and others relating to their need to meet the needs of society at the time of readers and writers, accountants, staff, and indeed these madrassas have succeeded in preparing the individual for life in accordance with religious and moral ideals that advocated by Islam. Which encouraged these madrassas to spread, especially since the state were not educational services of their competence at the time, but the competence of individuals and groups. The traditional education in the Arabian Gulf in general and Bahrain in particular the first seed to learn, and that was popularly educated, not officially, but it shows the interest of the Gulf society in general and specifically in science education and Bahrain.2 - Soon, there has been an education is something new not seen in the region before and had an impact on the functioning of the educational process in the Arabian Gulf in general and Bahrain in particular, and prepared by some of the first signs of modern education in the Gulf, but it is education system introduced by the missionaries of America, and although the goals those missions colonial and motivated by the foundation is the preaching of Christianity in the Arabian Peninsula and convert the population to Christianity, but Zwemer and his colleagues practiced by missionaries and other activities do not represent the reality of the missionary religious goals, including medical activities and educational and cultural and archaeological and geographical, but the (US - Arab mission) It failed in its mission, because it linked the provision of basic services, a mission of evangelization be Christians, because Muslims and Arabs in general very special clinging to their religion and will not accept them an alternative.3 - private education charity in Bahrain at the beginning of the twentieth century, specifically in 1919, and was intended to proceed with the civil committees from various segments of society, whether local or expatriate, to develop the first foundations for the nucleus of formal education in Bahrain, and also came in reaction to the Education Ketatibi which He prevailed in that period and which now does not meet the wishes of the community, especially after the first World war, as things have changed and resulted in the opening up of Bahrain more broadly on data from modern Western Renaissance to make a big political and social changes in the country resulted in the emergence of cultural and social awareness among the members of the community of Bahrain, so there was a need to create a modern educational institutes differ from Koranic schools in terms of systems and curricula and goals. However it was this kind of education does not achieve scientific adequacy fit the spirit of the age.
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الاستاذ الدكتور صادق السوداني ومنهجه في كتابة التاريخ == Prof. Sadik Al - Soudani (Ph.D.) And His Method In History Writing

Author name: بسام رضا محمد
Supervisor name: كريم مطر حمزة الزبيدي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: An update of what initiated by researchers and historians studying the decades since the Iraqi mission joints of modern and contemporary history of Iraq through letters and Alatarih. And as far as the educational aspect has been many studies about the reality of education in Iraq it was discussed at the Royal and Republican covenants, including the doctoral thesis presented by Saleh Mohammed Abdullah tagged (the development of education in Iraq from 1945 to 1958). It is noted on these studies addressed the educational system structure only, ignoring the role of the scientific elite in the development of the scientific basis and development of education in Iraq, whether education in the initial stages (primary, secondary) or higher education, and did not receive light on the role this elite benevolent in this area. Proceeding from this and that decide to choose the subject with praise by the Scientific Committee in the department. The study is detailed and covers an important missing link of the history of education in Iraq, which cast a shadow over Iraqi society directly. In line with the interest of the Department of History at the College of Education / University of Babylon, studying the role of the early pioneers of leading academics historians who have left a clear imprint in the educational process in the country, we discussed the Master in the College of Education ten years ago dealt a prominent Iraqi historians, Dr. Kamal appearance Ahmed, then a series of historical studies dealing with these scientific personalities. In Baghdad University / College of Arts recently discussed the first two letters of Dr. Jafar - khasbak and the second for Dr. Saleh al - Abed, in the College of Education at the same university also discussed a message for Dr. Faisal Al - Samer, in the Department of History, University of Diyala also discussed the first two letters of the historian Fadel Hussein and the second for Dr. Hashim al - Tikriti. This academic scientific studies and contributed to bring the unique messages of its kind, as these studies did not discuss the personal life of the historian only, but dealt with his writings and his approach to the study and teaching of history, which is important because of the ignorance of most ((historians)) Iraq's new now, the foundations of the Iraqi school so to speak, or at at least those who are the pioneers of this school is founded by laid off or the first girls to her? These studies can give a clear picture of the aforementioned question. This study consists of an introduction, three chapters and a conclusion, eating in the first chapter "of his life and his social science". He held the title of the second chapter; "the evolution of the historical vision and scientific activities".The third chapter is devoted to the study of his approach based on an analytical study of historical writing. A number of conclusions have been reached during the study, the most important ones are : 1. Bon we can say through the study of His analytical study of both books by or books translated or scientific research that his approach to historical writing clear since completing his thesis. Since then he charted himself a peculiar approach it based on historical themes eating away at the analytical study tendencies and fancies in the interpretation of the historical event. What reinforces this saying his thesis and research published a master student, as well as upgrade research presented by the year 1978, but this does not mean that his studies at the University of Exeter in the United Kingdom has not changed or has not achieved any change to the method not vice versa increased scientific sobriety and convictions its methodology in historical writing2. Was his method of unique and based supervise the review of what is written by the student carefully read the letter more than seven of taking out the messages and Atarih impact readings proud of the scientific departments, which studied there, and went researchers from rattling become them later receipts and tours in the area of research scientific.3. Calculated for Dr. Sadik Sudan in the field of historical studies include : - A great interest in Jewish history and synthesizes translation, he wrote three thousand (Zionist activity in Iraq (1914 - 1952); the Jews of the United States; (A Brief History of the Jews of Iraq) and translated two books (a coil of the history of the Jews; chapters of the history of the Jews).(B) is the first to introduce the idea of writing letters and thesis in European history in the Department of History / Faculty of Arts / University of Baghdad, and at that time the idea has not lived up to many of those concerned with history, but after not long supported it and excited her.(C) the first to introduce the subject of the case the Irish studies instruction through the teaching of the subject ((international problems of historical and contemporary)) and supervision, as Ashraf proudly on the message Master of the College of Arts / University of Baghdad and four thesis PhD from the Irish case two in the Faculty of Arts, University of Baghdad and two in the Faculty of Education / University of Mustansiriya, a total of 7, the title of the late Dr. Saleh al message Irish case was one of the proposal and was one of the members of the committee discussed. In the proposed B + C has opened up new horizons for the students to record their messages and Atarihhm. After you have exhausted or nearly titles, especially those concerning Iraq.(D) Dr. Sadik Sudanese, to my knowledge is the only one who read a minimum of seven readings as may be up to ten in order to show a message or thesis, supervised by the student and the supervisor, which is unusual and unprecedented, embodies Sudan's keenness on the level of messaging and Alatarih that bears his name as a supervisor, a little something to his credit.
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محمد حسن الطالقاني ودوره الفكري حتى عام 2003 == Mohammad Hassan Al Talqani And Intellectual Role Until 2003

Author name: هند اشهاب عبد الحسين
Supervisor name: نعيم جاسم محمد
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Contributed their writings in addressing important issues that affect the cultural and social reality as it issued anumber of cultural magazines and that the most important AL - Najaf knowledge magazine (1958 - 1961). By its founder and editor Mr.Mohammad Hassan AL Talqani has lived through a critical stage and the task of modern histoey of iraq after he moved from the system royal to the republican system in 14 july 1958 directed its attention researcher highlight the personality of Mr.Mohammad Hassan AL Talqani and intellectual role until 2003 when he enjoyed the prestaige and scientific seminar since he is from Najaf prestigious families who had a prominent role in the scientific , cultural and literary life in Najaf in particular and Iraq in general. the study consisted of the introduction and chapters and aconclusion to the most prominent conclusions reached by the researcher then avital annexes variety touched directly the life of Mr.Mohammad Hassan AL Talqani then followed by the sources relied on by this study The first chapter on the distribution of five sections studied the first section the birth and lineage of Mr.Mohammad Hassan AL Talqani as well as the place of his birth. the second section has included prominent media family and the statement of translations and the conduct of the most prominent of translations and the conduct of of the most prominent scienlists as Mr.Mihammad Hassan AL Talqani and Mr.Mashror AL Talqani and Mr.Abdul - Rasul AL Talqani.The second chapter titied cultural role of Mr.Mohammad Hassan AL Talqani has branched in to five sections Highlighted to raise the intellectual and the most prominent books published and unpublished and highlighted on the book which originally master message obtained Mr.Mohammad Hassan AL Talqani from Jesuit University in Lebanon estimate of (very good) grade.This chapter also discussed the books that made the most important part of the religious writings. the most important (AL tadiagnh) , Religion basics the achievement of the court of Hashem AL kaabi.Third chapter studied the political activity of Mr.Mohammad Hassan AL Talqani in terms of his position of the internal political developments , practicularly the Royal system (1921 - 1958) and his position on the 14 july revolution , Shawwaf movement in Mosul 1959 As well as his position on the coup of 8 february 1963.The other topic dealt axpatriate political currents and the position of which Mr.Mohammad Hassan AL Talqani. And in particular his position of the current communist and the scholars liberal group. highlight on the situation of political in the Arab ocean.The last section to his death and the most prominent participants in the memorial service
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الهبات والهدايا فـي الاندلس من الفتح حتى نهاية عصر الطوائف (92 - 484هـ/711 - 1091م)

Author name: زينب حسن نجم
Supervisor name: محمد عبد الله المعموري
General topic: History
Specific topic: Islamic History
Degree: Master
Language: Arabic
University location: Babylon
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التعليم المهني في العراق (1968 - 1979) : دراسة تاريخية == Vocational Education In Iraq From 1968 - 1979 Historical Study

Author name: محمد احمد ياسر الحسيني
Supervisor name: مشتاق طالب حسين الخفاجي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
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هنري الثاني والتطورات الداخلية في انكلترا 1154 - 1189م == Henry II And Internal Developments In England 1154 - 1189

Author name: عباس فخري حمزة
Supervisor name: ماجد محيي عبد العباس الفتلاوي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Wrong to consider that the Middle Ages are the dark ages in the history of human civilization in general and in the history of Europe, in particular, but the student portion of those historical times do not find this description, but are eras led and helped in one way or another in the evolution of European societies through what we found in drafting and enacting laws and building the foundations of military, economic and physical state, which contributed to the development of the individual's personality EU in general and English in particular, and stimulated the spirit of creativity in which England was part of that civilization, which are available on the study, and what has been deduced from this is : 1. The submission of England to the authority of a foreign after it was divided into several small kingdoms warring with each other, to a great empire is the French Empire represented governing Normandy and its founder, William of Normandy aka polymerase light, which led to the fusion of two cultures and the emergence of French tiles and correspondence and culture in general language.2. punish other families on the new rule that kingdom by marrying a Albulantegent family represented by King Henry II, who inherited the property on by his French wife, which included French provinces to England until he became nicknamed the King of England and France, a former first in English history continued in addition to the Other titles of the king of England to Ages late.3. lay the foundations of a solid English kingdom during the reign of King Henry II reforms in all political, economic, religious and constitutional fields.4. create a central management system strong through all of inclusion and feudal barons and clergy and cavalry under the authority of the king and activating the role of civil courts as well as ecclesiastical courts. Which is contrary to the feudal system, therefore we can consider it a revolution or change radically shook feudal entity.5. led those actions to the occurrence of England in the internal and external conflicts was the religious establishment and the barons and even within the royal family, supported by a king of France when he saw him in the Kingdom Alanjuih of the danger that was threatening the French empire, as well as of the Pope of the Catholic Church in Rome's role in the defense their interests and privileges within the territory English and who saw it has shrunk as a result of what he had done, King Henry II to enact laws that would limit the privileges of the clergy and the Church in England.
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الصراع على السلطة في ايران (1796 - 1848) == Conflict For Power In Iran (1796 - 1848)

Author name: بركات الزهراء محمد جابر العوادي
Supervisor name: كريم مطر حمزة الزبيدي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The history of Iran has engaged researchers and learners since it includes sanguinary conflicts which cost the Iranian society so many sacrifices. The struggle for the throne has become controversial among most historians. The reasons and results of this struggle require more accuracy and investigation to get better acquainted with the issues behind these struggles. We have seen that the period between 1796 - 1848 is the most fertile period in the political events and fluctuations. This prompted me to study and explore this period and most salient events.Often, internal struggle in any society is attributed to deteriorated and unequal external relationships. This was what Iran underwent during the period under consideration. In this study, we have reviewed these struggles in details in the body of the study, and we denoted to their reasons and results. In doing so, we used important references that shed light on this period of the Iranian History which were rich with political events that ultimately led to diversity in struggle parties. The study consists of four chapters taking into consideration the chronological order of events. The first chapter deals with the struggle for power in Iran in 1797. This chapter focuses on the events during the reign of Karim Khan Al - zand which lasted from this year to the accession of Agha Mohammed Shah and the murder of Karim. The second chapter deals with the overall internal and external conflicts in the period 1797 - 1828. These internal sanguinary struggles paved the way to external struggles which ultimately led to the weakening of Iran from inside. Chapter three examines the results of external struggles, especially with Russia, and results of the conclusion of Turkamnji Agreement with Russia which considerably contributed to the deterioration of the situation in Iraq and played a significant role in the internal and external Iranian history. Among the important results of this agreement the Carnage of the Russian Embassy in 1829 and the regional internal conflicts. To completed historical information, the fourth chapter is added. It is entitled “Struggle of power and general situation in Iran after the death of Ali Shah”. This period is characterized by its rich historical events, increased competition for power, and appearance of claimants for the throne. The period of Mohammed Shah reign represented a critical point of his struggle with his competitors. After reviewing the political, economic, and social events of this period, we came out with a number of results; prominent among them is that the internal struggle in Iran had paved the way to the interference of neighboring states in its affairs. This led to external wars and their implications that laid their shadow on the life in Iran. This situation led to a series of internal conflicts which had took different shapes and reflected on the conflicts between the reigning dynasty and people. It also led to the outbreak of anti - government revolutions and movements in which rulers used all types of atrocities and excessive force to quell these movements. Due to these wars, the Kachar Dynasty was weakened and their reign dilapidated due to these long wars and defeats accompanied them, as well as due to the Russian Embassy Carnage in Tehran which was a reflection to the rage of the people against their rulers. Despite all this, the authorities did not succeed in finding a good way out of these political and economic crises which lasted to the reign of Shah Mohammed. Revolutions and movements continued due to the policy of the Shah and his retinue.Though we have stopped at the year 1848, internal struggle for power continued and movements continued to harass the reigning powers due to the weakness of authorities and death of the Shah.
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بيار الجميل ودوره السياسي في لبنان (1905 - 1984) == Pierre Gemayel, His Political Role In Lebanon (1905 - 1984)

Author name: عارف عبد الحسين عباس الفتلاوي
Supervisor name: مشتاق طالب حسين الخفاجي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: There is no denying the fact that writing the biography of prominent figures is a very hard task, especially such important figures as Pierre Gemayel. Leading the biggest sectarian party in Lebanon, Kataeb (phalanges), Pierre Gemayel played an important r
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بنو حنيف ودورهم السياسي والفكري حتى نهاية العصر الراشدي (41 هــ / 661 م) == Bnu - Hunaif And Their Political And Intellectual Role Until The End of The Rashidion Age (41 H / 661 A.D)

Author name: حيدر عبد الامير نعمة السيلاوي
Supervisor name: عبد الستار نصيف جاسم العامري
General topic: History
Specific topic: Islamic History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The family of Bani Hunaif Is one of the prominent families in the history of islam and she is from the supporters of the tribe of Aws, and this family entered in Islam before the prophets Emigration to the (city of Madina).As it was one of the members of
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ايران في عهد الامام الخميني : دراسة في السياسة الداخلية (25 شباط 1980 - 22 حزيران 1981) == Iran During The Reign of Imam Khomeini Study The Internal Politics (25Th Feb 1980 - 22Nd Jun 1981)

Author name: احمد فليح حسين الجبوري
Supervisor name: فؤاد طارق كاظم العميدي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Modern and contemporary history of Iran indicated a great importance to many researchers and historicals. the political events in Iran 1980 had great importance because it formed the first government stems and it was characterized by a new system which wa
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الاقصاء السياسي في تاريخ العراق المعاصر 1921 - 1953 م == Political Exclusion In The Contemporary History of Iraq 1921 - 1953

Author name: صلاح هادي عبادة الحلي
Supervisor name: يحيى كاظم حمود المعموري
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The Royal era of Iraq is stated as the first presidency in which Iraq was converned interiourly. That was after Iraq had its freedom of British and Uthmanian occupation; and that represented the virtual raise of its aged history by the virtue of Iraqis''
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الاسر الاقطاعية ودورها السياسي والاقتصادي في لواء الحلة 1921 - 1958 == Political And Economic Role of Feudal Families In The Hillah City 1921 - 1958

Author name: احمد صالح حذية عبادي المعموري
Supervisor name: وفاء كاظم ماضي الكندي
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Political, economic and social factors under which the Iraqi society lived at the end of the ninetieth century and early twentieth century played an important role in the emergence of feudal families as a social class having a considerable weight, especia
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الاحصاء السكاني في العراق (1947 - 1965) : دراسة تاريخية == Statistical Population In Iraq (1947 - 1965) : Historical Study

Author name: فاتن مهدي خيري عبد الامير الدليمي
Supervisor name: سعد كاظم حسن المولى
General topic: History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Researchers and historians Iraqis population studies did not the Iraq,s population census in particclar aclear interest, as they went out to study the history of Iraq,s political fear without interest in shedding Light on non - political matters Al anadra
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شيخ الاسلام تقي الدين بن دقيق العيد (ت : 702 هـ / 1302 م) : دراسة في حياته السياسية والفكرية == Sheik of Islam Taqi El - Deen Bn Daqeek Al - Eid (702 A.H. / 1300 A.D.) : A Study In His Political And Notional Life

Author name: ميسون عباس عناد
Supervisor name: عبد الستار نصيف جاسم العامري
General topic: History
Specific topic: Islamic History
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: Arab and Islamic civilization overabounded with a lot of scientific figures that contributed in nourishing History withachievements, works and honoured situationswhich have the favour in recording those achievements on the pages of History and one of thes
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العلاقات المكانية للتلوث الصناعي في مدينة الحلة == Spatial Relations Of Industrial Pollution In Hilla City

Author name: رؤى علي مهدي كاظم جوازري
Supervisor name: جبار عبد جبيل
General topic: Geography
Specific topic: Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يعد التلوث البيئي وخاصة الناتج عن الصناعة اعتداء سافر من قبل الانسان على البيئة وتوازنها والذي يؤدي الى تشوه وازالة المظاهر الجمالية فيها، ونتيجة لعملية طرح الملوثات الصناعية الضارة بالبيئة والتي بدات تهدد الوسط الهوائي والمائي والتربة , فقد جاءت هذه الدر | Pollution of environment is very danger which causes deform the beautiful situations especially industerail pollution which is caused by human. Because of industrial waste.It is damage air ,water and soil.There is a stady called "relationship of industerail pollution in Al Hilla town" It provides many important ways to benefit from these waste soil,gas, but with fewer effect of factories. This study help us to know the effect of waste on the environment balance in Hilla.It is found that industry is polluted for systems of our life in danger way. That over'centre organ for statics in Babil.Then,They are taken plece or model to examin them in the laboratory in Babil also in ministry of science ,Technology and Green AL Qasim university which relate to air ,water,soil pollution.They are used Equation of USA of growth of pupolation.The study is continued definition for some terms conserned the research.It also explaned the main role of natural elemants that their effect on in dustrail pollution Especially weather and its elements as winds.Even Human effects rise pollution because of increasing population which increase the Use of earth or people rong use for elements of environment without right plan previously.The air, water and soil pollution is caused defect at Ecological system which redounds life.There are some good points that have benefit as some technological ways which make pollution fewer even its economic cost.The study suggest some suitable indormations for some factories to achieve the gaol.

واقع واتجاهات النمو الحضري للمدن الصغيرة في قــضاء المحاويل == The Reality Of Urban Growth And Trends In Small Size Cities In Al - Mahaweel District

Author name: شيماء محمد خليـل محياوي
Supervisor name: عامر راجح نصر
General topic: Geography
Specific topic: Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تناولت هذه الدراسة احدى اهم الظواهر الحضرية وهو النمو الحضري الذي يعد من اعقد العمليات واكثرها تاثيرا على المراكز الحضرية والوحدات العمرانية من خلال تعرضها للتغير المستمر لمختلف الوظائف. وسلطت الدراسة الضوء على ظاهرة تكرر اغفالها عن برامج التنمية والخطط | This study examined one of the most important urban phenomena and urban growth is one of the most complex operations and most influential urban centres and physical units through exposure to the constant changing of various jobs. The study highlighted the phenomenon repeats overlooked about development programs and strategic plans (small towns) that population size ranges between (5000 to 20000 ) individual , which consists in the study area in three urban centres, shared several qualities and functions (Al - Mashroa ,Al - Neil, Al - Emam). I have discussed the study highlighted the reasons for the growth of the city is not without undergoing a range of geographical disciplines such as location and position and the nature of the surface water and soil resources that contribute to the emergence and local environment conditions imposed, and the human factors of population and economic, social, historical and political origins of the important role of cities. I have used several courses of study as a descriptive analytical and historical and morphological approach drawing on quantitative methods and software for geographic information systems (Gis) and quadruple (swot) analysis method in analysis of urban land uses, and field visits with use of a number of tables, maps and graphs to illustrate geographic phenomena in the cities studied. The study showed the planning stages of cities and urban land use planning stages through to each city and analysis of functional proficiency through capita account depending on appropriate planning standards. The study also showed the vision for urban growth and magnitude of future need for urban land uses until 2025 and showed some parameters which stands in front of the urbanization of the study and determine the appropriate directions for growth. The study concluded with a set of conclusions and recommendations that contribute to improve the reality of urban growth in the cities study and the possibility of development commensurate with the economic, social and cultural characteristics

المناخ واثره في التباين المكاني لزراعة المحاصيل الصناعية في العراق للمدة (1981 - 2012م) : دراسة في المناخ التطبيقي == Effect Of Climate On Spatial Variation Of Industrial Crop Cultivation In Iraq For The Period (1981 - 2012) AD A Study In Applied Climatology

Author name: سحر جابر كاظم سالم الغزالي
Supervisor name: علي مهدي جواد الدجيلي
General topic: Geography
Specific topic: Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يتضمن البحث دراسة "اثر المناخ في التباين المكاني لزراعة المحاصيل الصناعية في العراق"، وقد اختيرت لهذا الغرض عشر محطات مناخية موزعة على منطقة الدراسة من الشمال الى الجنوب، كما اعتمدت الباحثة على معلومات مناخية للمدة (1981 - 2012)م، من محطات منطقة الدراسة ال | The research study the “effect of climate on spatial variation of industrial crop cultivation in Iraq”.Ten climate stations where chosen for this purpose, the stations where distributed within the study area from North to South.The researcher has collected climate data for the period (1981 - 2014) AD, from the climate stations of the study area, which belongs to the Iraqi Meteorological Organization and Seismology. : 1. The climatic requirements of the industrial crops plays a key role in crop distribution according to the appropriate areas, where some crops is concentrated in a certain area without another due to the nature of the climatic conditions that determines its availability.2. Through analyzing the climatic properties of the study area, it has been concluded that some climatic elements have a key role in determining an appropriate area for industrial crops cultivation. The theoretical and actual radiance hours, temperature, and rainfall plays an important role in the distribution of the industrial crops.3. The study showed that the industrial crops have a big economic importance, where they contribute in developing industry. However, the total cultivated area from (2002 - 2012) AD and the Donum productivity is unstable from year to year.4. The study concluded that some climatic elements contribute in spreading pathogens such asthe above maximum temperature, below minimum temperature, over relative humidity, or wind contribution in spreading viral diseases.5. Radiance hours, temperature, rainfall, and climatic elements have direct effect on the distribution of industrial crops, the study area have appropriate radiance hours for industrial crops cultivation. Except for Flax, where the actual radiance is not enough to cultivate it.6. The temperature of the study area is appropriate to cultivate all of the industrial crops with a variation of some crop.The study area is experiencing water deficiency during the growth period of industrial crops, except for some months, this is what clarified by analyzing water consumption tables for the studied crops and subtract it from rainfall quantities. Which requires relying on other irrigation technics to give the crop enough water

العلاقات المكانية لانتاج واستهلاك مياه الشرب في مدينة الحلة == Spatial Relationships For Consumption And Production Of Drinking Water In Hilla City

Author name: دنيا ابراهيم محسن الحسناوي
Supervisor name: عايد سلوم حسين الحربي
General topic: Geography
Specific topic: Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تم اجراء الدراسة (العلاقات المكانية لانتاج واستهلاك مياه الشرب في مدينة الحلة ) بالاعتماد على تقدير عدد السكان في منطقة الدراسة لسنة 2013 وبالاعتماد على تقديرات دائرة الاحصاء ومن ثم جمع المعلومات من دائرة الماء في منطقة الدراسة فيما يخص القدرة الانتاجية ل | The study (spatial relation of production and consumption of drinking water in the city of hilla )was conducted depending on the estimate of population in the study area for 2013 based an census department and then collect the information from the water department in the study area in terms of production capcity of water filter projects and the storage capcity. in addition to capcity of the pumping station at a time with working hours and other information about transportation , distribution and estimate the product water quantities networks per day and for the distribution of water to the population in the study area to determine the future need. And then multiplied by the person share with the expected number of the population in 2025. in addition , the collection of samples for laboratory testing to departmine the quality and characteristics of drinking water (physical , chemical , biological ) and use of previous examination of the departments concerned (Department of Enviroments ) and for the pourpose of comparison and matching the results to realistic and comprehensive and the results of the above study wrer standing on the weaknesses in the process of production , transmission and distribution of drinking water for the development of solutions and recommedations for the provision of safe drinking water terms of quantity and quality , This serves the geographic case in the urban and industrial nature of the stdy area to suit the future needs to ensure that no expansion of population or industial randomly because of potable water is available some where and inevitably in other place in the study area.

ايرادات العراق المائية من نهر دجلة : دراسة في الجغرافية السياسية == Iraq Water Resources From Tigris River (A Study In Political Geography)

Author name: رفل حسين نجم
Supervisor name: سعدون شلال ظاهر | حسين وحيد عزيز
General topic: Geography
Specific topic: Geopolitics
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تزايد الاهتمام بالمياه دوليا واقليميا مع بداية النصف الثاني من القرن الحالي وقد صاحب هذا الاهتمام بروز مظاهر الخلاف المتصاعد بين الدول المتشاطئة في احواض الانهار الدولية, لذا تعد المياه واحدة من اهم مرتكزات الامن الوطني في اي بلد في العالم لاسيما في الا | The importance of water internationally, regionally and locally has increased with the beginning of second half of the current century. This concern has accompanied with occurrence arising disagreement aspects among coastal countries in worldly rivers poo

التمثيل الخرائطي لاستعمالات الارض الزراعية في قضاء الحلة باستعمال نظم المعلومات الجغرافية GIS == The Cartographic Representation To The Agriculture Land Uses In Discrete of Al - Hila Using Geographical Information System (Gis)

Author name: زهراء حسين يوسف الشريفي
Supervisor name: عبد الزهرة علي الجنابي | عايد سلوم الحربي
General topic: Geography
Specific topic: Human Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تعد الخارطة وسيلة مهمة في ايضاح الظواهر المختلفة لسطح الارض وبيان العلاقات التي تربط بين مختلف هذه الظواهر وعلاقتها بالانسان ونشاطاته المتنوعة, اذ لا يقتصر استخدام هذه الوسيلة على الجغرافي وحده فبامكان التخصصات والعلوم الاخرى الافادة منها ايضا, وكانت هنا | The map is one of the most important means that are used for explaining different phenomena on the surface of the earth and showing the relation between these phenomena and their effect on human activities, Although they can be used in different fields of

قضاء الهاشمية : دراسة في الجغرافية الاقليمية == Al - Hashmiya District A Study In Egional Geography

Author name: عواد عبود مطر ال واوي
Supervisor name: عامر راجح نصر
General topic: Geography
Specific topic: Human Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تهدف دراستنا الجغرافية الاقليمية في قضاء الهاشمية في الكشف عن الامكانات الطبيعية والبشرية والاقتصادية للاقليم من اجل تحليل التباين المكاني داخل حيز الاقليم فضلا عن انه يهيئ الامكانات الاقتصادية والحضارية ويحاول الوصول الى تفسيرها وايجاد الحلول المناسبة له | The aim of present study of regional geography in Al - Hashmiya District is disclosure about natural, human economic abilities for this regional to analysis the dissimilarity into the area since, this also to ready the economic and civilization abilities,

تحليل جيوبوليتيكي للمصالح الصينية في اقليم دول جنوب شرق اسيا == Geopolitical Analysis For Chinese Interests In The Region of States of Southern East of Asia

Author name: جواد كاظم عباس
Supervisor name: ماهر اسماعيل ابراهيم الجبوري
General topic: Geography
Specific topic: Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The subject of this study is so important as this subject didn’t get the sufficient concern in the previous academic studies especially when we realize that states of southern east of Asia are considered as much important states in the Asian continent, th

تحليل التباين المكاني لساعات السطوع الشمسي في العراق وعلاقته بقيم الاشعاع الشمسي الواصل للمدة (1980 - 2011) == Analysis of The Spatial Variability of The Solar Brightness For Hours In Iraq And Its Relationship To Radiation Connecting The Values For The Period (1980 - 2011)

Author name: سرى عبد الهادي مخيف
Supervisor name: عبد الحسن مدفون ابو رحيل
General topic: Geography
Specific topic: Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يعد السطوع الشمسي والاشعاع اهم عناصر المناخ لتاثيرهما على حياة الانسان ونشاطاته المختلفة 0تهدف هذه الدراسة الى(تحليل التباين المكاني للسطوع الشمسي في العراق وعلاقته بكميات الاشعاع الواصل للمدة 1980 - 2011) بالاعتماد على ثمانية محطات للرصد الجوي وهي (الموص | Solar radiation and brightness considered of the most important climate elements because it effect on the person life and his different activity. This study aimed to Analysis the spatial variation of the solar brightness in Iraq and its relation with the

الخصائص المناخية لمحافظة القادسية ومدى ملائمتها لزراعة المحاصيل الصناعية فيها باستخدام نظم المعلومات الجغرافية (GIS) == The Climatic Characteristics of Al - Qadisiyah Governorate And Their Suitability For The Cultivation of Industrial Crops Using Gis

Author name: حيدر مظهر عبيد الخيكاني
Supervisor name: عبد الاله رزوقي احمد كربل | عايد سلوم حسين
General topic: Geography
Specific topic: Agricultural Geography
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يعد المناخ من المقومات الرئيسية لزراعة المحاصيل الصناعية بما يتضمن من عناصر المناخ (الضوء،الحرارة،الرياح،الرطوبة،الامطار) ولقد اهتم البحث بدراسة الخصائص المناخية لمحافظة القادسية ومدى ملائمتها لزراعة المحاصيل الصناعية فيها لذلك تضمن البحث اربعة فصول تناول | Atmosphere is a key requirement in the growth of industrial crops, including its elements of light, temperatures, wind, humidity, and rain. This research studies the Climatic characteristics of Al - Qadisiyah governorate and their suitability for the cult

اثر تغيرات اسعار النفط الخام العالمية في تمويل الموازنة العامة للمدة 2003 - 2014 : دراسة مقارنة العراق والسعودية == Effect of Change In Global Crude Oil Prices In The Financing of The General Budget For Period (2003 - 2014) A Comparative Study of Iraq And Saudi Arabia

Author name: شيماء عبد الهادي حسين الشريفي
Supervisor name: خالد حسين علي المرزوك
Specific topic: Banking & Finance Science
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The impact of fluctuations in crude oil prices in the financing of the general budget for the period (2003 - 2014) and the extent of the link between the two as linked to balance all of the Iraqi economy and the Saudi closely linked to prices of global crude oil, which confirms the existence of a direct correlation between where increasing public budget increased prices and reduced the signal decreases and to approve both countries balance heavily on unilaterally source (oil) to get a large portion of overall revenues and this in turn has led to an imbalance structure of production as the majority of the GDP and output of the commodity sectors derived from the oil sector (mining and extractive industries) as it acquired this sector the largest proportion during the period of research. As for other sectors, it does not constitute a tiny alansph of GDP, has reached a researcher to several conclusions, including that oil revenues are the foundation of the specified public expenditure, which was characterized by imbalance as a result of the focus on the running costs of more than investment expenditure, this reflects consumer nature for both countries and that of oil exports the largest proportion of total exports and the adoption of the GDP in Iraq's biggest oil sector occupied than it is in Saudi Arabic. In light of results have been achieved for a number of recommendations, including the need to diversify sources of revenue (non - oil) and then by raising tax awareness among the citizens, raising the efficiency of tax systems in my sample as recommended by the researcher to the need to address the imbalance in the structure of GDP through activating the role of other sectors, and the need to provide for the activation of the role of investment expenditure in all production areas favorable investment environment, leading to the diversification of the productive base.

اثر سعر الصرف الاجنبي على النمو الاقتصادي في العراق للمدة (1990ـ2015) == The Impact of Foreign Exchange Rate On Economic Growth In Iraq (1990 - 2015)

Author name: حوراء عبد الزهرة جواد السلطاني
Supervisor name: احمد خليل الحسيني
Specific topic: Economy
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: هدف البحث الى ايضاح الاثار الاقتصادية لتقلبات سعر الصرف الاجنبي امام الدينار العراقي في معدلات النمو الاقتصادي خلال المدة (1990 - 2015)، وتحديد اتجاه تلك الاثار وطبيعة تاثيرها على الاقتصاد العراقي، كما ان الاقتصاد العراقي شانه شان جميع البلدان النامية تع | The study aimed to clarify the economic effects of the Iraqi dinar exchange fluctuations in economic growth rates during the period price (1990 - 2015), and to determine the direction of these effects and the nature of their impact on the Iraqi economy. The Iraqi economy, like all developing countries exposed to many of the economic imbalances and even more sharply since the early nineties and until now, which led to the loss of the factors of economic stability, and then the absence of an enabling environment for economic growth, due to wars and blockades Iraq experieuced, the weakness of domestic resource mobilization, and the increased reliance on external financing, in addition to the external debt problem. However these are the wrong economic decisions which had an influential role in most of the distortions and crises the Iraqi economy suffers from. Thus the importance of the study lies in the role that could be played by the exchange rate in effect on economic growth rates in Iraq and the advancement to overcome the problems. The study starts from the premise that " The fluctuations of the Iraqi dinar exchange rate has a negative impact on economic growth variables and their impact more pronounced as compared to the stability of the exchange rate; a neutral effect". To achieve the objectives of the study, there are three chapters, the introduction and conclusion.Chapter One : the theoretical and conceptual framework of the exchange rate and economic growth.Chapter TWO : The indices measure the exchange rate trends and economic growth in Iraq.Chapter Three : Measuring the impact of exchange rate in the economic growth of the Iraqi economy. The current study used a form of analysis record (VAR) and through a standard program (E - views), that depending on the stability of the time series as preprocessing results indicate. all model variables as stable at the level of the moral level of 1% and the level of significance of 5%, and then tested joint integration, that proved the existence of a long - term equilibrium relationship between the independent variables and the dependent variable, then the estimate vector autoregressive (VAR) to the variables of the study.

قياس وتحليل اتجاهات النمو الاقتصادي في دول عربية مختارة مع التركيز على العراق للمدة 2000 - 2013 == Measurement And Analysis of The Trends of Economic Growth In Selected Arab Countries With A Focus On Iraq For The Period 2000 - 2013

Author name: مينه عبد الحسين كريم الفتلاوي
Supervisor name: احمد خليل الحسيني
Specific topic: Banking & Finance Science
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: تعد دراسة النمو الاقتصادي لاي بلد من المواضيع المهمة والصعبة لان اهميته تتاتى من ضرورة استمرار تاثر النمو الاقتصادي وتطوره واستدامته مع الزمن من اجل تحقيق هدف التطور وتعزيز الرفاه الاقتصادي لعدد السكان الحالي والمستقبلي. فان عملية النمو للبلدان العرب | The study of the economic growth of any country is an important topic and it is difficult at the same time its importance comes from the need to continue to be affected and the evolution of economic growth and sustainability over time in order to achieve the goal of developing and promoting the economic well - being of the number of current and future population.The growth process of the Arab countries selected in the study (United Arab Emirates, Egypt) may be an easy and understandable. There is no need to complicate it for the enjoyment of their economies, the kind of stability and diversity of resources, while in Iraq, the issue is complex and thorny for of several aspects, some dating back to previous eras and the other due to political and security events experienced by the country up to the present.Therefore, the study cited in the first chapter (theoretical framework for economic growth and economic development) are distributed in three sections are : - Section one : - Theoretical framework for economic growth.Section two : - Sources of economic growth.Section three : - Theoretical framework for economic development.Chapter two is divided (analysis of Economy variables for the sample countries and Iraq for the period (2000 - 2013)) into three sections : - Section one : - Analysis of the UAE economy variables.Section two : - Analysis of the Egyptian economy variables.Section three : - Analysis of the Iraqi economy variables.Chapter three (the measurement and analysis of the economic growth of the sample countries and Iraq for the period (2000 - 2013)) deals with two topics namely : - Section one : - Characterization and formulation of standard models.Section two : - Determination and analysis of standard forms elected.The third chapter is tests the Stability of growth indicators included in the standard models by testing unit root (Test Dickey Fuller expanded), where the results indicate that the growth indicators of the UAE and Egypt are stable at the second difference and the level of significance is of 5%. As in Iraq, the indicators of growth has stabilized in the first difference and the level of significance is of 5%. also tests the common integration (Johansen) to see if there is a long - run equilibrium relationship between economic variables? It has a test of causality (Granger) to see the mutual influence between the growth indicators Is it a one - way? Two - way? Or there is no effect ?these variables to help determine the knowledge of what has been achieved of this development of whether this development is purposefully directed through economic plans or was the will of fate ; and that this is what has already been achieved in accordance with the curriculum adopted since been reviewed economic growth indicators has been reviewed by Digital facts and at the macro level for the period (2000 - 2013) in addition to using economic methods of measurement through a production function model (Cobb - Douglus) and the model of (Kaldor) and methods of mathematical measurement through model (Harrod - Doumar) to know the level of economic growth in those countries as well as in support of the analysis which was based on Digital facts. Where it turns out that the best model for the Production Function (Cobb - Douglus) is in Egypt, where the flexibility of the labor (salaries and wages) 0.23 and flexibility of the total fixed capital formation 0.22, the best model for Kaldor is in the UAE productivity parameter which was larger than the one is 2.174 denoting a high production efficiency, and the best model of Harrod - Doumar was in Iraq as the Iraqi economy achieved a maximum rate of economic growth in 2004, reaching 35.13%.

قياس اثر الارتداد الزمني في تفسير مسار دالة الاستهلاك في العراق : دراسة تطبيقية للمدة (1997 - 2012) == The Measuring of The Impact of Time Lag On Determining The Path of The Consumption Function In Iraq - An Application Study For The Period (1997 - 2012)

Author name: اطياف عصام حسين الجبوري
Supervisor name: حسين ديكان درويش الدليمي
Specific topic: Banking & Finance Science
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يهدف البحث الى تحديد وقياس اثر نماذج الارتداد الزمني على سلوك ومسار دالة الاستهلاك في الاقتصاد العراقي للمدة (1997 - 2012)، فقد تم تقسيم البحث الى ثلاث فصول لغرض تحقيق فرضيته واهدافه ولغرض الوصول الى هذه المنهجية استخدمت الباحثة البرامج الاحصائية الجاهزة | The research aims to determine and measurement the effect of the Lag models on the behaviour and trend of the consumption function in Iraq economy for the period (1997 - 2012 ). also , the research was divided into three chapters in order to reach it's hypothesis and aims ,to reach this methodology the research use (ols ) Technique related with ( EView 7 , SPPS , Excel ) statistical packages to estimated more than (30) Econometrics models , besides The research reaches some important conclusions which refers to the vital effect of Lag models specially ( MBA ) to draw the path and trend of the consumption function in Iraq comparing with other Lag models such as (Koyck , Almon , Friedman , and Duesenberry) , moreover , the Lag models is also play a vital role in explain and determining the process and the mechanism of fiscal and monetary policies in Iraq for the same period. finally , the research recommends to formulate anew scope of the ( Wealth ) variable more than ,the meaning of monetary supply (M2) in order to use this through the Lag models related with , also , it is important to plan the marginal propensity to consume in the Iraq economy through the consumption function in order to raise the Investment activity and economic growth.

تاثير خصائص تصميم العمل في الخيار الاستراتيجي التنافسي : دراسة استطلاعية في الشركة العامة لصناعة السيارات في الاسكندرية ومعمل سمنت الكوفة == The Effect of Work Design Characteristics In The Competitive Strategic Choice An Exploratory Study In Kufa Cement Plant And The General Company For The Automotive Industry In Alexandria

Author name: ريام عامر ريس الفيحان
Supervisor name: زينب عبد الرزاق عبود | كامل شكير الوطيفي
Specific topic: Industrial Management
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: سعت هذه الدراسة الى تحديد تاثير خصائص تصميم العمل في الخيار الاستراتيجي التنافسي ولاجل ذلك اعتمدت هذه الدراسة خصائص تصميم العمل (الاستقلالية, وتنوع المهارات، وتحديد المهمة، وهدف المهمة، والتغذية العكسية) بوصفها متغير مستقل، اما الخيار الاستراتيجي التنافسي | This study Intended to determine the work design characteristics effect of on competitive strategic choice and for that has been the adoption of the work design characteristics (autonomy, skills variety, task identity, task significant, feedback) as an in

اثر اللوجستك العكسي على حماية البيئة : دراسة تطبيقية في الشركة العامة لصناعة البطاريات في بغداد

Author name: ميس حسين امين العميدي
Supervisor name: مجبل رفيق مرجان
Specific topic: Industrial Management
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: سعت هذه الدراسة الى تحديد اثر اللوجستك العكسي في حماية البيئة كدراسة تطبيقية في الشركة العامة لصناعات البطاريات في بغداد.وحددت مشكلة الدراسة من خلال اثارة التساؤلات الاتية : - ما مدى تاثير اللوجستك العكسي على حماية البيئة ؟ - هل هناك علاقة بين اللوجس

تاثير اعادة تصميم العمليات في التميز بادارة المشاريع : دراسة حالة في شركة الواحة للمشروبات الغازية والعصائر والمياه المعدنية واللدائن وصناعة الاغطية البلاستيكية المحدودة == The Impact of Redesign Operations on The Project Management Excellence A Case Study of Al Waha Company For Soft Drinks, Juices And Mineral Water

Author name: بسمة مهدي الحسيني
Supervisor name: امل عبد محمد علي | عادل هادي البغدادي
Specific topic: Industrial Management
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: الغرض : الكشف عن العلاقة والتاثير بين اعادة تصميم العمليات والتميز بادارة المشاريع.التصميم/ المنهجية/ المدخل : لقد تم تصميم استمارة استبانة، وقائمة فحص، لكشف العلاقة والتاثير بين متغيرات الدراسة، وباستخدام عينة عشوائية مقدارها (43) فردا وقد تم توزيع الجزء | Purpose : To detect the relationship and the impact between the re - design processes and achievement of excellence in project management.Design / methodology / Portal : A questionnaire form was developed form, a checklist, to make sure of the existence o

اثر ممارسات ادارة سلسلة التجهز في الاداء الاستراتيجي == The Effect of Supply Chain Management Practices on Strategic Performance

Author name: اسراء سعد عبد الكاظم
Supervisor name: عباس حسين الحميري | كامل شكير الوطيفي
Specific topic: Industrial Management
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: سعت هذه الدراسة الى تحديد تاثير ممارسات ادارة سلسلة التجهيز في الاداء الاستراتيجي، ولاجل تحقيق ذلك اعتمدت ممارسات ادارة سلسلة التجهيز بابعادها (الشراكة الاستراتيجية مع المجهز، علاقات الزبائن، مستوى ونوعية تشارك المعلومات، التاجيل) فيما تم التعبير عن الاد | This study has sought to determine the effect of the supply chain management practices on strategic performance. In order to achieve this goal, the study adopted supply chain management practices including (strategic partnership with the supplier, custome

اثر السياسة المالية في مؤشرات اداء سوق الاوراق المالية في العراق والامارات للمدة (2004 - 2014 ) == Effect Fiscal Policy In Stock Maket Perfomance Indicatos In Iraq And UAE For The Period (2004 - 2014)

Author name: محمد جاسم شهيد القريشي
Supervisor name: عياد محمد علي باش
Specific topic: Banking & Finance Science
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: جاء هذا البحث لبيان الاثر الذي يمكن ان تتركه متغيرات السياسة المالية المتمثلة بالنفقات العامة والضرائب في مؤشرات اداء سوقي العراق ودبي للاوراق المالية للفترة من (2014 - 2004) ومدى الارتباط بينهما, وذلك من خلال دراسة واقع السياسة المالية في البلدين اعتمادا

دراسة تداولية للمغالطات في الخطابات السياسية البريطانية والامريكية == A Pragmatic Study of Fallacies In British And American Political Speeches

Author name: دعاء خريبط فاضل
Supervisor name: فريد حميد حمزة الهنداوي
General topic: Foreign Languages
Specific topic: English - Language
Degree: Master
Language: English
University location: Babylon
First pages:
Abstract: المغالطة هي ظاهرة خرق فن المناورة الشائعة كثيرا عند السياسيين في محاولاتهم لاقناع المتلقي بان وجهات نظرهم صحيحة. الا ان هذه الظاهرة لم تحظ بالاهتمام المرجو على الرغم من اهميتها مما جعلها تتطلب الكثير من البحث العلمي الدؤوب. وبناء على هذا فان هذه الدراسة | Fallacy is a derailment of strategic maneuvering which is quite often appealed to by politicians in their attempts to persuade others that their points of view are right. However, it seems that this field of language use has not been given its due attenti

اثر استخدام اسلوب الاثارة غير المنتظمة في تحصيل طالبات الصف الخامس العلمي في مادة الاحياء وتنمية التفكير العلمي لديهن == The Effect Of Using The Style Of Excitement In The Collection Of Non - Performing Students In The Fifth Grade Science Neighborhoods Substance And The Development Of Scientific Thought To Have

Author name: زينب محمد مجيد الجبوري
Supervisor name: عبد السلام جودت جاسم الزبيدي | ندى سعد ناجي الطائي
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: هدف البحث الحالي الى التعرف على اثر اسلوب الاثارة غير المنتظمة (الاثارة العشوائية) في : 1. تحصيل طالبات الصف الخامس العلمي في مادة الاحياء.2. تنمية التفكير العلمي لدى طالبات الصف الخامس العلمي في مادة الاحياء.ولغرض التحقق من هدفي البحث وضعت الباحثة الفر | The current research aims to find out the effect of using thrills irregular pattern (random excitation) in the collection of fifth - grade students in the neighborhoods of scientific material and the development of scientific thinking to have, and for the purpose of verifying the goal of the research and the researcher developed hypotheses Elsafreeten following cases : - 1. There is no difference statistically significant at the level (0.50) between the average scores of the experimental group students who are studying biology according excitement irregular pattern (random thrills) and the average score of the control group students who are studying the same material according to the conventional method in achievement test.2. There is no difference statistically significant at the level (0.50) between the average differences in grades pre and post tests for students in the experimental group who were studying biology according excitement irregular pattern (excitement random) and the average differences in grades pre and post tests for students the control group who were studying the same material according to the traditional way of thinking about the development of scientific testing.In order to validate these hypotheses conducted researcher experiment lasted an entire semester of the academic year (2015 - 2016) was chosen experimental design (with a partial seizure) of two unequal One is a pilot, and the other officer was limited research on students fifth grade science bio In one of the Directorate of schools public to raise the province of Babylon, as has been selected sample randomly, which were represented by (junior Revolution Girls) spread over four study people (a - b) two divisions biotic (c - d) applied two divisions, was chosen Divisions (a - b) biogenic for not Okamalhn Articlescientific because of the presence Courses system was chosen Division (a) draw random to represent the control group as numbered (36 students) and Division (b) to represent the experimental group and numbered (37) students and the total number of students research sample was (73) students were rewarded with two sets of search a group of the following variables : age, calculated in months, IQ (Raven Raven), degrees neighborhoods substance in the chorus the first test for the academic year 2015 - 2016, educational attainment of the parents, the former information in the subject of biology test, the test of scientific thinking and identified scientific article last four seasons ( IV, V, VI, and VII) of the biology textbook for fifth grade science bio, (i 4.2014),Saat researcher behavioral objectives of Article educational as numbered (165) behaviorally target, and the researcher built a collection tested b (50) checksums paragraph of multiple choice with four alternatives, either tool II has represented tested scientific thinking, which consisted of six sections as the first section and the second, third and fourth paragraphs it consists of seven and section V and VI of the six paragraphs. As used researcher statistical methods Ala?tah : (test Altaia for two independent samples, and a box (Ca 2) and equation Pearson coefficient Spearman correlation equation coefficient of difficulty, excellence and equivalent efficacy wrong) alternatives, was applied experience in the second semester as it was the beginning of the actual teaching (28.02.2016 ) and the end of the actual teaching (28/04/2016) when the data processing results showed statistically significant superiority of students who have studied according excitement irregular style of the experimental group (random excitation) on the contro In light of the results : - 1.oost researcher on the need to adopt the excitement irregular pattern (random excitation) in teaching biology to fifth grade bio - scientific because of its positive impact in raising the achievement and the development of scientific thinking for the students level2.oost researcher teachers and teachers need to pay attention to the use of excitement irregular pattern (random excitation) in teaching and give it a privileged position within the teaching process. Mayati researcher suggested : - 1.ojra similar study to demonstrate the effect of non - performing style thrills (random excitation) in the other study variables and other stages.2.ajra similar study to demonstrate the effect of non - performing style thrills (random excitation) in the last study materials
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اثر تدريس قائم على الدفاع عن وجهات النظر في تحليل النصوص الادبية عند طالبات الصف الخامس الادبي == The Impact Of Teaching Based On Defending Points Of Views In The Analysis Of Literary Texts By Fifth Literary Female Students

Author name: ميادة حمزة عبد الواحد حمادي
Supervisor name: رغد سلمان علوان الجبوري
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: ان البحث الحالي يهدف الى معرفة اثر تدريس قائم على الدفاع عن وجهات النظر في تحليل النصوص الادبية عند طالبات الصف الخامس الادبي، لذلك اخضعت الباحثة تدريس الدفاع عن وجهات النظر للتجريب لمعرفة اثره في تحليل النصوص الادبية لدى طالبات الصف الخامس الادبي في ما | The current research aims at understanding the impact of teaching based on defending points of views in the analysis of literary texts by fifth literary female students. To this end, the researcher applies this kind of methodology to trace its impact in the analysis of literary texts by fifth literary female students. To achieve this aim, the researcher has chosen Al - Zarqaa preparatory school for girls randomly. Similarly, class section B has been chosen to represent the experimental group which amounts to (21) students, whereas class section A to represent the control group which amounts to (21) students as well. As such, the total number of the participants is (42) students. The students of the two groups (the experimental and the control) have been proved to be compatible with reference to the following parameters : 1 - their ages counted by months2 - their fathers' educational attainment3 - their mothers' educational attainment4 - their first course final results in the Arabic language subject of the year (2015). The researcher has limited the teaching material used during the experiment period and she has also put forward the behavioural aims for the eight topics that she has taught to the two groups. They are (116) behavioural aims. The researcher has taught the two groups by herself during the experiment period which lasts for eight weeks. It starts on the 21st of February 2016 and ends on the 19th of April 2016. Another point is that the researcher has prepared teaching plans for the materials to be taught during the experiment period. Some of these teaching plans are handed to experts and specialists to check their validity. At the end of the experiment, the researcher has applied a literary text to be analyzed by the students and the answers are checked according to, after its validity and credibility has been showed by the researcher, Al - Esawi's criteria (2005). The researcher has used the following statistic means : 1 - T - Test for two independent samples; 2 - Chi - Square; 3 - Pearson correlation equation; and 4 - The percentage equation After statistically analyzing the findings, the researcher reaches the following conclusion that is the experimental group students, those who are taught literary texts according to the modern way of teaching, have exceled over the control group, those who are taught according to the traditional way. In the light of these conclusions, the researcher recommends that : 1. Teachers should resort to the strategy of defending points of views in the analysis of literary texts because of its impact on students' performance and this is evident through the positive results of the current research.2. Teachers should be taught how to use the strategy of defending points of views. Put in other words, the ministry of education should establish a special program to guide teachers through the process of this strategy in the analysis of literary texts.3. Experts and specialist supervisors from the ministry of education should explain the importance of using the strategy of defending points of views because of its important impact and its brilliant results. They should guide teachers how to use this strategy and its bright steps so that students can adequately be taught the literary texts.4. Teachers should go in line with the new advanced directions and ways used in teaching the Arabic language and one of these directions is the strategy of defending points of views. This strategy has been found of pivotal importance in creating thinking and guiding serious teaching to achieve the required results. The researcher suggests the following : 1. The application of a similar study on students of other preparatory stages.2. The application of a study to understand the reasons behind students weaknesses in the analysis of literary texts with the intention to discuss these weakness to delimit their difficulties. 3. The application of a comparable study between the strategy of defending points of views and other recent strategies that work on developing students creative thinking
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اثر استراتيجية البطاقات المروحية في تحصيل طالبات الصف الثاني المتوسط في قواعد اللغة العربية == The Impact Of The Fan Cards Strategy In The Collection Of Second Grade Students At The Average In The Arabic Language Rules

Author name: رسل جعفر صادق عبكه
Supervisor name: زينة جبار غني الاسدي | رائدة مهدي جابر العامري
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: ترمي الدراسة الحالية الى تعرف ( اثر استراتيجية البطاقات المروحية في تحصيل طالبات الصف الثاني المتوسط في مادة قواعد اللغة العربية )، وللتحقق من هدف الرسالة صاغت الباحثة الفرضية الصفرية الاتية : - "ليس هناك فرق ذو دلالة احصائية عند مستوى ( 0,05 ) بين متوسط | The present study aims to identify the effect of the card strategy in the achievement of intermediate second grade students in the Arabic grammar. In order to verify the objective of the thesis, the researcher formulated the following zero hypothesis : "There is no statistically significant difference at (0.05) between the average score of students in the experimental group who study Arabic grammar using the card strategy and the average score of students of the control group who study the same subject in the usual way." The researcher chose a experimental design with partial control of the research groups (experimental and control). She chose randomly the average chastity for girls from the middle and secondary schools in the center of Babil Governorate. The sample was 60 students for the academic year 2015 - 2016, The researcher randomly selected (D) to represent the experimental group (31) students who studied the Arabic grammar using the strategy of the cards and the (C), which represented the control group, and (33) students studied in the usual way. The researcher was statistically rewarded between the students of the research groups (experimental and control) in the following variables : (the age of time calculated in months, the academic achievement of the parents, the academic achievement of the mothers and the grades of the students of the research groups in the Arabic grammar for the first semester of the second grade for the current academic year (2015 - 2016). ~ As for the teaching plans, the researcher prepared a set of teaching plans for the groups to be taught to the experimental and control groups. Two of these plans were presented to a group of experts and specialists to express their opinions on their suitability and suitability for teaching.In order to measure the achievement of the students of the two research groups in the subjects studied by the researcher themselves, a final collection test was prepared, consisting of (30) multi - choice test cases, presented to a group of experts and specialists to verify the validity of the test and to process it statistically using the appropriate statistical means. After the end of the ten - week experiment, the final achievement test was applied to the students of the two research groups. After analyzing the results of the students' responses and their statistical processing, using the T - test, , 05) for the experimental group.Based on the results of the research, the researcher concluded : The students of the experimental group outperformed the students of the control group. In light of this result, the researcher recommended using the card strategy in teaching Arabic grammar at this stage because of its effect on increasing student achievement. Similar to the current study on other study samples such as (grade I average, middle school).
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تحليل محتوى كتاب قواعد اللغة العربية للصف السادس الادبي في ضوء المدخل الوظيفي == Analyzing The Content Of The Book Arabic Grammar For Sixth - Grade Literary In The Light Of The Functional Entrance

Author name: حسين علي رهيف
Supervisor name: عارف حاتم هادي الجبوري | اسعد محمد علي النجار
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: The current research aims to book Arabic grammar sixth - grade literary content in the light of the career portal analysis, and to achieve this goal deliberately researcher to review the literature and studies on functional entrance formulate standard for career entrance consists of (20) items and then presented to the gentlemen experts specialized curricula and methods the teaching of Arabic language and literature in order to express their views and their observations, and in the light of their observations been added some paragraphs and modify others, that completed the search tool and reach the final image to the standard functional entrance consists of (22) subparagraph branching of three dimensions : (functional in the text and supply and examples) and (functional in the grammatical rules) and (functional in the exercise), then proceeded to the researcher analyzed the book Arabic grammar content according paragraphs of standard dimensions, and to ensure the stability of the analysis used a researcher first two methods a sample of the content of the book of other analysts analysis, and other re - analysis between the researcher and the same after a specific period of (21) days; and using equation (Holsta) totaled reliability coefficient between the researcher and the first analyst (0.83) and between the researcher and the other analyst (0.87) and between the researcher and the same (0.92).For the purpose of extracting the results used researcher frequencies and percentages of the dimensions and compared to the percentage of the mean dimensions in order to know the extent achieved, the study resulted in the following results : 1. Check the first dimension of the career entrance standard, which reads (in functional text and display examples) and not to check dimensions, which read (in functional grammar) and (in the functional exercise).2. In the first dimension of the standard career portal that reads (functional in the text and display examples) achieved the following paragraphs (devoid of grammatical and stylistic and spelling errors) and paragraph (their structures formulated clearly and easily and free of ambiguity) and paragraph (focusing on the practical side of the base grammatical) and paragraph (check the integration of Arabic grammar and language skills : listening, speaking, reading and writing) in most of the subjects of the book, did not materialize paragraph (includes practical models which can be exposed to learners in their daily lives)3. In the second dimension of the standard career portal that reads (functional in grammar) the following paragraphs have been achieved (exposed to the subject of grammatical necessary in linguistic communication, which permeates the lives of students) and paragraph (compatible with learners' cognitive growth) and paragraph (progress in achieving integration between topics as studied by students) and paragraph (check gradient in its presentation in terms of difficulty) and paragraph (devoid of differences grammarians on the base grammatical one) and paragraph (formulated and clear, her words brief), while not achieved some of its clauses, such as paragraph (avoid grammatical structures is used to contact linguistic and that fall within the grammar topic studied).4. In the third dimension of the standard career portal that reads (functional in the exercise) Check the followingparagraphs (suit formulated teacher objectives, which focus on the side of the application) and paragraph (a specific reply and does not accept guessing) and paragraph (carrying students to touch the moral differences between tool and tool) in most of the exercises book, not paragraphs realized (including vertebrae test students' knowledge of the function of grammar method subject matter) and paragraph (working to enable students to employ the floor inside syntax) and paragraph (working to provide students with the ability to employ grammatical Qaeda in communication processes linguistic career) and paragraph (exercises include unresolved focus on the practical side career with the rules of grammar) in most of the subjects of the book, while there are passages did not materialize in the exercises the whole book, namely, (that enable students to employ syntax within the text) and paragraph (include clauses to address the mistakes of grammar common in the language of the students) and paragraph (carrying students to move a number of poetry or prose texts that offer them anonymous, from the shape and movements).In light of the search results, the researcher suggested a number of conclusions, including : 1. The one dimension of career entrance has been achieved the standard dimensions of others did not materialize.2. Sub - paragraphs of the dimensions of a standard doorway career is almost similar between the subjects of the book achieved.In light of these findings and conclusions researcher recommended a number of recommendations including : 1. Dependence on dimensions of career development at the
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تحليل محتوى تدريبات كتب القراءة العربية للمرحلة الابتدائية في ضوء مهارات التفكير الاساسية == Analysis Of Training Books In Arabic By Reading The Content Of The Basic Thinking Skills

Author name: عباس محمود عبيد
Supervisor name: سيف طارق حسين العيساوي | رائدة مهدي جابر العامري
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يهدف البحث الحالي الى تحديد مهارات التفكير الاساسية اللازمة لتلامذة المرحلة الابتدائية , ومدى توافر تلك المهارات في تدريبات كتب القراءة العربية للمرحلة الابتدائية , ولغرض تحقيق هذين الهدفين عمد الباحث الى مراجعة الادبيات والدراسات التي تناولت التفكير ومه | The current research is aimed at analyzing know necessary for the students of the primary stage of basic thinking skills, and the availability of those skills in exercises Books in Arabic reading of the primary school, in order to achieve these goals, the researcher reviewed the literature and studies on thinking skills, prepared a list of the skills of basic thinking consisted of nine skills, And then presented to some experts and specialists gentlemen in the curricula and methods of teaching Arabic language and to express their views around, and by for that have been modified and add and delete some paragraphs, that completed the search tool and reach the final image of the list of basic thinking skills, then proceeded to the researcher analyzed the training content reading books on according to the basic thinking skills, and to ensure the stability of the analysis used a researcher method of analysis with the help of others Analysts using equation (Holsty) totaled reliability coefficient between the researcher and the first analyst (0.91%) and between the researcher and the other analyst (0.85%) and between the first analyst another analyst (0.80%). For the purpose of extracting the results used researcher frequencies and percentages for the skills of basic thinking and yielded more results : The higher the skill of achieving the (application) skill by (35.90%), then (pager) skill by (30.20%), followed by (comparative skill) by (11.11%), then (note) skill by (9.40%), then (a skill ranking) by (4.56%), and (codec) skill by (3.99%) and (definition problems) skill, by (2.85%) and (the skill of asking questions) by (1.14%), and finally the skill (ratings) by (0.85%). by for the search results researcher recommended a number of recommendations, including : the need to develop curriculum based on field studies accurate and closer, and sensitive to the tastes of the students and their orientation and mental level, and taking into account the integration and coordination of Books in Arabic reading to include the skills of basic thinking, in terms of size and quality of educational material and activities and training commensurate with the mental level of students each row of the elementary grades, and the need to enrich the training exercises to help students develop thinking and Building inventories cognitive them. Complementing this research suggested the researcher several proposals, including : conducting a similar study of the current study in exercises written Arabic language rules for the primary stage analysis in light of the skills of basic thinking, conduct a pilot study entitled : The Impact drills enrichment in language ability Development when pupils primary school in Arabic reading material.
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اثر التدريس على وفق النظرية التواصلية في الاداء التعبيري لدى طالبات الخامس الادبي == The Effect Of Teaching According To The Communicative Theory In The Expressive Performance Of Students Of The Fifth Literary

Author name: سارة حسين عبد عون الجبوري
Supervisor name: حمزة هاشم محيميد السلطاني
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: يعد التعبير اهم فروع اللغة العربية اذ يفصح عن الافكار والمشاعر وعن طريقه يستطيع الفرد الكشف عن المتحدث او الكاتب وعن مواهبه وقدراته وميوله، ويمثل التعبير نشاطا ادبيا واجتماعيا فهو الطريقة التي يصون بها الفرد افكاره واحاسيسه بلغة سليمة مكتوبة او منطوقة، | The expression is considered the most important branches in Arabic language as it discloses the speaker's or the writer's thoughts and feelings besides his or her ability, talents or inclinations. The expression also represents social and arts active. It is the way that protects the person's feelings and thoughts by a neatly language and means of communication between the person and the other people. By it, she or he can understand what he need and make them understand what they need from him in the same way. In spite of the importance of the expression, it is still studying by the way that depends on indoctrination and memorization. Therefore, the researcher thinks that the students need a new method for teaching, which helps them to expand and enrich their knowledge, develop mind skills; directions or inclinations by depend on dialogue and discussing the information. On the other hand, give the pupils chance to express their new ideas and make them in different forms so as to encourage them to be able to make questions and inquiries about information. According to that, the researcher wanted to do her studying which is called "The Effect of Teaching according to the communicative theory in the Expressive Performance for Fifth Students Literary Branch "In order to achieve the aim of the research, she supposed" Null Hypothesis" : There is no related differences with statistically significant between the average pupils scores at the semantic level of (0.05) and between the experimental group students who are studying the way of expression with communicative way and between controlling group of students who are studying the expression in the usual way. In order to achieve the aim of the research, the researcher has chosen Al Zarqa School from the preparatory and High Schools which the number of the division not less two of the fifth literary stage. The researcher relied on the random method and with same way; she has chosen the B division to become the experimental group and the division A to become the controlling group. The research sample was 42 by 21 students in the control group and correspond researcher between the two groups in chronological age and educational attainment of the parents and degrees of the first course of the academic year. The researcher applied in the second half of the academic year 2015 - 2016 and continued to apply the experience classrooms full at the end of the experimental the researcher conducted a final test of the expressive unified theme for the two female researcher and corrected papers on Al - Hashemi according to standard adopted by the researcher.The researcher handled statistical data by using ({t} - test for two independent samples; test kai square, Pearson correlation coefficient).The results showed superiority of the students in the experimental group to the controlling group in the expressive performance.The search is over to a set of recommendations including : 1. Train the students to talk about their experiences and their observations with a correct and proper language in addition to a focus on topics that close to the environment of the students and their minds.2. Determine the curriculum or curriculum for the teaching of expression and giving it an important sufficient like all other branches of the Arabic language.3. Encourage the students to foreign reading then using it in their lesson expression.4. After she had completed the research, the researcher proposed a similar study of the current study on other branches
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اثر انموذج مارازانو في اكتساب المفاهيم الاحيائية وتنمية التفكير الناقد لدى طلاب الصف الخامس العلمي == The Effect Of A Marazano Model In The Biological Conceptes Acqwiring And The Development Of Critical Thinking For Students Of Fifth Scientific Class

Author name: حيدر خليل عزيز عيسى
Supervisor name: وفاء عبد الرزاق عباس العنبكي | عباس حسين مغير الربيعي
General topic: Educational Sciences
Degree: Master
Language: Arabic
University location: Babylon
First pages:
Abstract: هدف البحث التعرف على اثر انموذج مارازانو في : 1. اكتساب المفاهيم الاحيائية لدى طلاب الصف الخامس العلمي(الاحيائي) في مادة علم الاحياء. 2 - تنمية التفكير الناقد لدى طلاب الصف الخامس العلمي(الاحيائي) في مادة علم الاحياء. ولغرض التحقق من هدف البحث تم صياغة ا | The current research aimed to identify the impact of a Marazano model in : - 1 - The acquisition of the biological concepts acquring for students of a fifth - grade science (bio) in biology.2 - The developing of the critial thinking for the students of a fifth - grade science Development (bio) in Biology. For verification purposes of goal search, The folowing zero hypotheses following for mulated.1 - There is no statistically significant difference at the level of (0.05) between the average scores of the experimental group students studying biology at Marazano model and the average score of the control group students who are studying the same subjects in accordance with the traditional method in acquiring biological concepts test.2 - There is no statistically significant difference at the level of (0.05) between the average scores of the experimental group students studying biology at Marazano model and the average score of the control group students who are studying the same subjects in accordance with the traditional method in the development of critical thinking test.To validate the hypotheses the researcher conducted experiment for two months since the adoption of the following actions : the experimental design was used (with a partial seizure) wiht tow eqwal growps the sample research were cloos rondomly from populetion of, which represents school junior government daytime and secondary centrally spend Hashemite and hand - Qasim and was (junior martyr Adel Nasser), since the number of fifth grade science students (bio) in school (63 students) distribued in to divisions were selected Division (b) which randomly assigned to represent the experimental group, which consisted of (32) students studying on according to a Marazano model, while the control group, which consisted students Division (a) has consisted of (31) students studying on according to the traditional mhted, has been rewarded researcher statistically between the two groups in the following variables : (Age measured in months, prevous achievement in Biology subject, the previous information test in Biology subject, pre - test of critical thinking) and identified Article scientific at three chapters (V, VI, VII) of the biology textbook for fifth grade science, has been extracted (20) main concept and (66)branched concept for these chapters, has been formulating behavioral objective as final numbered (120) behaviorally objectives as well the researder prepared (24) teaching plan for each of the experimental and control groups and then presented to the experts and arbitrators have been appropriate adjustments.With regard to reaserch tools the researcher. prepared. the two tools search marked by the construction of testing to acquire biological concepts depending on the main and branched concepts, as given three paragraphs test for each concept based on three cognitive processes (definition, discrimination, application) and bringing the number of paragraphs of the test (60) items paragraph of multiple choice ever (four substitutes) have been apparent sincerity and genuineness construction account, the coefficient of difficulty, and the coefficient of discrimination and the effectiveness of the wrong alternatives test the stability of tool were extracted by using the midterm reaching. after correction by Spearman - Brown equation (0.83) The second tool was critical thinking test which consisted of five sections, each component part of the three positions and every position on the three paragraphs were apparent sincerity and genuineness construction account, the stability of the test was a way to extract by Alachtbaraz reached after (0.86).The experiment was applied in the second semester of the academic year (2015 - 2016) and over (8) weeks, as was the beginning of the actual teaching on Monday (22/2/2016) and end on Thursday (21/4/2016) After application of the two tools of research and analysis wich results obtained by researcher by using a program (Microsoft Excel), results showed outweigh the sdustdent of experimental group whom stayded to acording to the a Marazano model the students on control of group whow studed erso on according to the traditional method in acquisition test of biological concepts and development critical thinking, in light of the search results, the researcher recommended the necessity adoption of a Marazano model in teaching biology to fifth grade science because of its positive impact in raising the level of the acquisition of biological concepts and critical thinking for students, as well as the reacher proposed dowing a similar study to demonstrate the effect an other variables stages and another.
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