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دراسة فسلجية لمرضى الفشل الكلوي قبل وبعد الديلزة في محافظة واسط A Physiological Study of Renal Failure Patients Pre And Post Dialysis In Wasit Province

اسم المؤلف: تمارة حمد احمد العقبي
اسم المشرف: كاظم جهيد كاطع الطائي هيثم قاسم محمد
الموضوع العام: علوم الحياة
السنة: 2015
الموضوع الدقيق: الحيوان - الفسلجة
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: واسط
الصفحات الاولى:
المستخلص: تم اجراء هذه الدراسة في كلية العلوم/ قسم علوم الحياة في جامعة واسط وبالتعاون مع مركز الكلية الصناعية في محافظة واسط للفترة من 1/10/2012 ولغاية 1/5/ 2013 لغرض دراسة التغيرات الفسلجية التي تحدث لمرضى الفشل الكلوي بنوعيه الغسيل الدموي والغسيل البريتوني قبل و| This study was conducted in the Department of Biology, College of Science, University of Wasit. The samples were collected in cooperation with artificial kidney center in AL - Kut Hospital, AL - Kut city, Wasit Province, during the period from 1 /10/2012 to 1/5/2013. In order to study the physiological changes of renal failure patients before and after hemodialysis and peritoneal dialysis. The blood samples were taken from one hundered thirty four patients for this study.The patients in this study were divided into two groups according to the type of dialysis : 94 hemodialysis patients, 52 males with age range (21 - 69) years and 42 females with age range (20 - 70) years, 40 peritonial dialysis patients, 24 males with age range (21 - 60) years and 16 females with age range (23 - 63) years. All results were compared with the results of 57 healthy person who were selected from both sexes (29 males and 28 female). Eight milliliters of venous blood were collected from control subjects and patients with renal failure by using disposable syringe of 10 ml before and after dialysis process.The blood analyses was conducted for evaluating the hematological parameters which are included (Hb, PCV, WBCs and PLT ) biochemical parameters which include (Blood Urea, Serum Creatinine, Total Protein and Calicum) electrolyte parameters which include sodium and potassium, measured concentration of (Erythropoietin and Aldosterone) hormone in patients with renal failure before and after dialysis and control groups and measure the effectiveness of phagocytic cells in patients with renal failure before dialysis by using Nitroblue Tetrazolium stain (NBT). The study revealed the following results : 1 - When comparing the results of parameters between before and after hemodialysis and peritoneal dialysis with healthy control show the following : a - Significant decrease (P < 0.01) in the levels of (Hb and PCV) while significant increase (P < 0.01) in PLT in renal failure patients before and after dialysis compared to healthy control and significant increase (P < 0.01) in the numbers of WBCs in male peritoneal dialysis patients compared to healthy control.b - Significant increase (P < 0.01) in urea, creatinine, sodium, potassium and in the aldosterone hormone concentration in renal failure patients before and after dialysis compared to healthy control.c - Significant decrease (P < 0.01) in the erythropoietin hormone concentration, total protein, calcium and phagocytic cells activity in renal failure patients compared to healthy control.2 - When comparing the results of parameters between before and after dialysis for each type of dialysis showing the following : - a - All hematological parameters and the concentration of hormones (Erythropoietin and Aldosterone) observe no significant differences between before and after dialysis.b - Significant decrease in the levels of urea, creatinine and there is a significant increase in the levels of total protein and calcium after dialysis comparing with before dialysis.c - Significant decrease in the levels of potassium in hemodialysis patients after dialysis comparing to before dialysis and there is a significant decrease in the levels of sodium and potassium after peritoneal dialysis comparing to before dialysis. 3 - When comparing the results of males and females hemodialysis with males and females peritoneal dialysis shows the following : a - Significant increases in numbers of WBCs before and after dialysis in the male and female peritoneal dialysis comparing with hemodialysis b - Significant decreases in the levels of urea and creatinine after dialysis in the male and female peritoneal dialysis comparing with hemodialysis.c - No significant difference in the levels of Hb, PCV, PLT, total protein, calcium, sodium, potassium, the phagocytic activity and the concentration of hormones (Erythropoietin and Aldosterone) before and after dialysis in the male and female hemodialysis comparing with peritoneal dialysis. We conclude that renal failure patients in Wasit Province suffer from severe anemia, high blood pressure, increase in the levels of urea and creatinine, disturbance in the levels of potassium, sodium and calcium with deficiency in the body's immunity.

تاثير المدعمات المختلفة في حاصل ومكونات الفطر الغذائي Agaricus bisporus واختبار كفاءته في عدد من المتغيرات الكيموحيوية والفسلجية في اناث الجرذان Effect of Various Supplementation in The Yield And Compositions of An Edible Mushroom Agaricus Bisporus And Evaluation of Its Efficiency in Some Biochemical And Physiological Parameters in Female Rats

اسم المؤلف: جمال جليل احمد البياتي
اسم المشرف: كركز محمد ثلج الجبوري عبد الله عبد الكريم حسن
الموضوع العام: علوم الحياة
السنة: 2015
الموضوع الدقيق: النبات
الدرجة: دكتوراه
اللغة: العربية
مكان الجامعة: صلاح الدين
الصفحات الاولى:
المستخلص: اجريت الدراسة في كل من مزرعة العرهون التابعة لقسم وقاية النبات - كلية الزراعة ومختبرات قسم علوم الحياة - كلية التربية للعلوم الصرفة في جامعة تكريت خلال المدة 1/9/2013 - 10/6/2014 تضمنت دراستين الاولى تم فيها تقدير تاثير اضافات متنوعة من المدعمات الكاربو | The study was conducted in each of the Al - Mushroom farm in Department of plant protection, College of Agriculture and the laboratories of Biology Department - College of Education for Pure Science at the University of Tikrit for a duration of 1/9/2013 to June 2014. The first studies were included the adding of carbon, nitrogen and other additives at casing period on productivity, quality characteristics and chemical composition of Agaricus bisporus mushroom. The results showed significant increased (p<0.05) in total production and biological efficiency when adding carbon supplement at 1% of starch and became 26.41 kg/m2 and 88.03% respectively, also with nitrogen supplement at 1% from Erbil feed (EF) that’s became at 23.20 kg/m2 and 77.33% respectively, compared with the same value in control group which at 21.68 kg/m2 and 72.26% respectively. Also both treatments were recorded earlier in production at 15 and 16 days after casing compared with 18 days in a control, while the qualitative characterizes has been the treatment of 3% from methionine the highest content of total antioxidants and became at 1975 µg/g dry weight compared to the 1572 µg/g dry weight in the control treatment, and the highest protein content was became at 40.32% in treatment of 1% of LB compared with 22.36% of their content in the control treatment. The treatment of 1% of EF was recorder as higher content from mineral of calcium, magnesium and iron at 390, 2574, 50.74 µg/g dry weight compared to the content in the control group at 290, 1683 and 37.64 µg/g respectively, and the treatment of sodium selenite 5% was recordes a higher content of selenium at 5.00 µg/g compared to the control treatment which at 4.00 µg/g dry weight. The treatment of EF also recorded a higher copper content at 108.60 µg/g dry weight compared to the control treatment which at 37.00 µg/g. The other study was apply to assessment the effects of replacing casein at 5, 10 and 15% by the Agaricus bisporus product from the treatments with starch and multi - vitamin and EF on some growth and physiological parameters in female rats feding for 28 days. The results showed that the presence of mushroom in food has caused a significant decline in weight. The present of mushroom powder at 5% in rats feed lead to significant increasing in hemoglobin and total account of RBC resulting in 12.53 and 6.36× 106 cell/mm3, 13.13 and 7.06× 106 cell/mm3, 7.36× 106 cell/mm3 for starch, multivitamins and EF, respectively, compared to 12.25 and 6.8× 106 cell/mm3, respectively. As well as the significant increased in the total counts of white blood cells that were at 5.50, 5.20 and 5.00 x 103 cells/mm3, respectively, with the starch, and at 5.70, 5.40 and 5.20 x 103 cells/mm3, respectively, with multivitamins and at 5.90, 5.50 and 5.40 x 103 cells/mm3, respectively, for the EF group compared with the control group were at 5.15 x 103 cell/mm3. also was significant increased in differential WBCs as lymphocytes with increasing the replacing percentage for treatments above. Also due the replace of casein by mushroom on proportions referred to in the above change in blood biochemicals parameters which significant decreased in urea, total cholesterol, triglycerides and low density lipoproteins and increase the concentration of high density lipoproteins, as well as reduced the activity of enzymes Alanine amino transferase (AST), Aspartic amino transferase (ALT) and Alkaline phosphatase (ALP) with increasing the percentage of replacing. As for the effect of replacing the same proportions of the mushroom instead of casein on growth and physiological characteristics of female rats with experimental diabetes induced by Alloxan and fed for 17 days. The results showed that the development of diabetes trial led to a reduction in the rate of animal weights and an increase in the relative weight of internal organs such as the heart, liver, spleen, pancreas and kidneys of infected sugar group, and became at 0.46, 4.39, 0.60, 0.46 and 1.19 g/100 g respectively when compared with the control animals, at 4.07, 0.42, 0.39, 0.23 and 1.04 g/100 g, respectively. And decreased of red blood cells that were at 5.93 x 106 cells/mm3, respectively, for the group affected by diabetes, while at 7.36 x 106 cells/mm3 respectively the healthy control group. And decreased WBCs in the infected animals with diabetes trial and became at 4.83 x 106 cells/mm3 compared with the healthy control group which at 7.03 x 103 cells/mm3. Also there was caused in significant increased in glucose concentration, which was on the first, 7th, 14th, and 17th days at 428, 405, 431.60 and 432.20 mg/100 ml respectively, in comparison with a control without diabetis that was at 123.33, 124.66, 126.33 and 125.33 mg/100 ml, respectively. Further to increased concentrations of urea, cholesterol, triglycerides and low density lipoproteins and a decrease in the values of high density lipoproteins also, increased the values of enzymes activity of each Alanine amino transferase(ALT), Aspartic amino transferase (AST) and Alkaline phosphatase (ALP) compared with the non - diabetic infected control group. That feeding female rats of experimental diabetes on the replacement rates of the mushroom instead of casein in their diet has led to the significant decline of the weight and relative weight of internal organs such as the heart, liver, spleen, pancreas and kidneys compared with animals infected with the induced diabetes with increasing rates of substitution. The results also showed that increased in total counts of red and white blood cells that was at 6.40 x 106 cell/mm3 and 5.00 x 103 cell/mm3 respectively when replacing 5% casein from mushroom compared to the infected control group were at 5.93 x 106 cell/mm3 and 4.83 x 103 cell/mm3 respectively. The substitution of casein with 5, 10 and 15% from mushroom was caused to significantly lower of glucose values to became 273.40, 251.60 and 302 mg/100 ml compared with control group infected which at 432.20 mg/100 ml. Also, because of the found of mushroom in the food was caused a changed in the biochemical blood, which significantly reduced the concentration of urea, total cholesterol, triglycerides, LDL and increase the concentration of HDL. As well as significantly reduced the enzymes (AST), (ALT) and (ALP) activity with the replacement rate increase compared with values in the animals infected with diabetes induced by Alloxan. The results concluded that the possibilty of use starch and EF at 1% for the commercial mushroom production. Mushroom also can be used as a food for lowering blood glucose, cholesterol, triglyseride, LDL and liver enzymes with increase in HDL for the people suffered from diabetes, obesity and heart diseases.

دراسة تشريحية مقارنة لبعض الانواع البرية من ذوات الفلقتين النامية في محافظة بغداد Comparative Anatomy of Some Wild Dicots Spp. Grown In Baghdad Province

اسم المؤلف: زبيدة عبد اللطيف اسماعيل
اسم المشرف: علي حسين الموسوي
الموضوع العام: علوم الحياة
السنة: 2014
الموضوع الدقيق: النبات
الدرجة: دكتوراه
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: The present investigation dealt with comparative anatomical characters of 29 selected wild species that belongs to different families growing in different parts of Baghdad Province. These species are : 1. Brassica deflexa Boiss.2. Brassica rapa L.3. Cardaria draba (L.) Desv.4. Sinapis arvensis L.5. Sisymbrium irio L.6. Strigosella africana (L.) Boch.7. Stellaria media (L.)Vill.8. Atriplex nitens Schkuhr.9. Chenopodium album L.10. Chrysanthemum coronarium L.11. Lactuca serriola L.12. Sonchus oleraceus L.13. Medicago polymorpha L.14. Melilotus indicus (L.) ALL.15. Vicia sativa L.16. Erodium cicutarium(L.) L'H17. Geranium rotundifolium L.18. Lamium amplexicaule L.19. Malva parviflora L.20. Plantago lanceolata L.21. Polygonum aviculare L.22. Rumex dentatus L.23. Ranunculus muricatus L.II24. Veronica polita Fries.25. Astrodaucus leptocarpus (Hoghst.) H. Riedl26. Urtica urens L.27. Verbena officinalis L.28. Lippia nodiflora (L.) Rich.29. Tribulus terrestris L.Some of these species have been anatomically investigated for the first time.Anatomical characters might be useful for plant biologist for the identification of important wild plants as an additional character at global level. Comparative anatomical characters were used; such as characteristics of ordinary epidermal cells of stems and leaves and stomatal complexes. The epidermis possesses number of important diagnostic character that offer valuable clues for identification, like size, shape, in addition to indumentum of both stems and leaves. Venation system was investigated and compared. Cross sections of root were useful taxonomically especially the thickness of epidermis, cortex, phloem and xylem. The study observed presence of sclerenchyma tissues in the root cortex of some species. Cross sectioning of stems and petioles were also studied. Epidermis, cortex, pericycle, vascular bundle shapes and numbers, pith characters, presence of crystals and tannin filled cells were useful aid in distinguishing species. Vertical sections of leaf blades, shape and number of vascular bundles, thickness of palisade and spongy layers and other mesophyll characters were important taxonomically.ccording to some of these characters, species were divided into groups. This study concluded the presence of variations in characters and these were presented for the first time comparatively, so that, the anatomical characters were a good support to the exomorphological characters in the studied species. Field photographs of the different studied plants and sections of organs were put in addition to numerous tables in this work. The above results were discussed scientifically regarding mainly the environmental factors.

دراسة التغايرات النسجية والمناعية لمرضى اللشمانيا الجلدية في محافظة ديالى Study The Histological And Immunological Variation of Cutaneous Leishmaniasis Patients In Diyala Province

اسم المؤلف: منى حميد احمد العزاوي
اسم المشرف: اسراء قاسم العبيدي
الموضوع العام: علوم الحياة
السنة: 2015
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: ديالى
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية على المرضى المصابين بداء اللشمانيا الجلدية والمراجعين لبعض المستشفيات والمراكز الصحية في محافظة ديالى للمدة من تشرين الاول 2013 ولغاية نيسان 2014. اذ بلغ عدد المصابين باللشمانيا الجلدية 115 مصابا وبمختلف المراحل العمرية يضاف لهم 25شخ | The present study was conducted on patients that infected with cutaneous leishmaniasis reviewing to some hospitals and health centers in Diyala province for the period from October 2013 to April 2014.The number of patients with cutaneous leishmaniasis was 115 in different ages in addition to them 25 person as a control group (uninfected). The proportion of infected women with cutaneous leishmaniasis ulcers was higher 56.522% than males 43.47%, the age group ten years and less was more group that being infected with rate 47.83% while the age group that rang from 71 to 80 was the less categories being infected in percentage 0.87% with a significant differences in the level of improbability less than 0.05. The presence of multiple ulcers was high 71.304% than single ulcers 28.696%. The presence of ulcers that length 1 cm and less (64%) more than other with more than 1 cm (36%) with statistically significant. The cutaneous ulcers were distributed on different areas of the body, the injuries on face was more 36.242% with anumber of 54 cases followed by upper limbs in rate 33.557% with anumber of 36 cases, the sore shoulder came latter with apercentage 1.342% in a significant differences at the level of improbability less than 0.05. The percentage incidence of cutaneous leishmaniasis was rise in kids and students in rats 33.043%, 39.130% respectively in a comparison with earners, housewives and of officers their percentages were 24.349% and 3.478% consecutively in statistically differences at 0.05 probability. The diagnosis of cutaneous leishmaniasis infections was done depending on clinical diagnosis based on the characteristics of the morphological and pathological ulcers, culture methods, impression smears and histopathological diagnosis. Clinical diagnosis for the cutaneous ulcer was recorded 100% percentage in comparison with culture method 10.435% versus 74.782%. percentage to positive smears, while the result of positive histopathological diagnosis was 88.571% on vision of promastigote of Leishmania parasite on semisolid medium while a adoption of existence amastigote from as appositive result of smears and histopathological method of the tissue biopsies taken from ulcer. The histopathological method was high efficiency supported clinical diagnosis when compared to other methods this rise in the diagnosis ratio has been demonstrated in significant differences in statistical probability less than 0.05.A study of amain impacts of histopathological changes in cutaneous ulcers on the infected skin layers at the level of light microscopy was also conducted. These pathological effects were in epidermis of skin including hyperkeratosis, pseudoepitheliomatous epidermal changes, ulcers and emergence of a dark colour, thickening in this layer accompanied suppurations and desquamation of chronic cases. As for the dermis layer, the inflammatory cells were infiltrate include plasma cells, macrophages, lymphocytes and eoisophils, disturbance in the order of layers especially in acute ulcers was taken, while the pathological effects were more in chronic ulcers as observed granulomatous inflammation and necrosis. The amastigote from were presence inside and outside the phagocytic cells.Aswell as some immunological changes that associated with the infection were studied in patients therapists by Pentostame (Sodium Stubogluconate) medication and uninfected control group by measuring the levelsof some cytokines IFN - ?, TNF - ?, IL - 12, IL - 17A and the chemokine MCP - 1. The level of IFN - ? was elevated in serum of cutaneous leishmaniasis patients and reached to 54.118±1.740 pg/ml, then the level was decreased during therapy and recorded 34.421±0.984 pg/ml after 1 - 3 dose a then dropped more after 4doses and more 22.489±0.795 pg/ml compared to uninfected control group 5.092±0.805 pg/ml. As well as the case of TNF - ? which rose their concentration in serum of CL patients and reached to 98.145±2.925 pg/ml, then decrease after treatment 71.507±2.901 pg /ml, 48.381±2.379 pg/ml after 1 - 3dose and more of treatment respectively, while the mean of TNF - ? in control group was 13.173±1.388 pg/ml.An increase in the level of IL - 12 was observed in the group of CL patients 845.598±16.273 pg/ml then the level was dropped during treatment and recorded 619.164±20.209 pg/ml, 495.578±27.038 pg/ml respectively but in control the concentration was 160.222±11.761 pg/ml. IL - 17A level was elevated in CL patients 227.268±5.027 pg/ml and decreased during therapy reach to 170.512±5.481, 126.443 ± 5.565 pg/ml after 1 - 3 doses and four doses and more respectively. The concentration of MCP - 1 chemokine was increased in CL patients 111.0397± 6.985 pg/ml then dropped during treatment 71.084± 2.636 pg/ml after 1 - 3 doses then dropped more 49.543± 2.167 pg /ml after four doses and more while they were in control 12.268 ± 1.609 pg/ml. The results of statistical analysis showed significant differences between these cytokines and their groups at the level of probability less than 0.05.

فعالية مستخلصات بعض الطحالب الكبيرة للفطريات الممرضة للنبات Activity of Some Macro - Algae Extracts Against Phytopathogenic Fungi

اسم المؤلف: دنيا يوسف محمد يوسف
اسم المشرف: عبد اللطيف محمد جواد
الموضوع العام: علوم الحياة
السنة: 2014
الموضوع الدقيق: النبات
الدرجة: دكتوراه
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: تضمنت الدراسة الحالية عزل وتشخيص طحالب كبيرة من بيئتين مائيتين محليتين مختلفتين. تم عزل ثلاث طحالب كبيرة هي Cladophora glomerata (N) وEnteromorpha rafsii من منطقه بحر النجف في محافظة النجف, في حين عزل Cladophora glomerata (R) من احد مبازل منطقة الراشدية ش | The present study includes isolation and identification of Macro - algae from two different environmental water bodies. Three Macro - algae were isolated, Cladophora glomerata (N) and Enteromorpha ralfsii from Baher Al - Najaf region in Holy Najaf city. In addition, C. glomerata (R) was isolated from Al - Rashdiya, north of Baghdad.Phytopathogenic fungi from soil and some infected fruits were also isolated. They were identified as Pythium ultimum and Rhizoctonia solani.Water and ethanol were used to extract each algae to evaluate their antifungal activity against isolated phytopathogenic fungi. Different concentrations of these algal extracts had been prepared which are (10, 25 and 50) mg/ml and the antagonistic activity against the isolated phytopathogenic fungi were evaluated, the hot and cold water extracts did not show any antagonistic activity against fungi. However, all these extracts were ignored in the future work for this study. Furthermore, the hot ethanolic extract was more efficient than these of cold ethanolic extracts. Results have been shown that there were significant differences when macro - algal ethanolic extract were used.C. glomerata (R), which isolated from Al - Rashdiya, was more efficient against tested fungi than the same alga what isolated from Baher Al - Najaf region. However, E. ralfsii extract was more efficient against tested fungi than C. glomerata (N). Percentage of inhibition against P. ultimum when hot ethanolic extract of E. ralfsii, C. glomerata(R) and C. glomerata(N) were (88.8, 83.3 and 63.3) respectively.However, results for cold ethanolic extract of the same algae were (63.3, 52.2 and 32.2) respectively when 50 mg/ml of algal extracts were used.Percentage of inhibition against R. solani when hot ethanolic extract of E. ralfsii, C.glomerata (R) and C.glomerata(N) were (94.4, 100 and 78.8) respectively.However, results for cold ethanolic extract of the same algae were (66.6, 64.4 and 48.8) respectively when 50 mg/ml was used. According to the difference in biological activities against those phytopathogenic fungi caused by the same species of macro - algae or different genera from different environments. Due to difference in biological activity of the same macro - algae species Physiochemical parameter for each environments obtained such as air and water temperature, Turbidity (NTU), Electrical Conductivity(EC)and Salinity%, Water pH, CA+2 concentration, Mg+2 concentration, Total Hardness and Total Alkalinity. Results indicated that soaked Cucumis sativus and Capsicum annum seeds in cold and hot ethanolic macro - algae extracts of (E. ralfsii, C. glomerata (R) and C.glomerata (N) for 24 hours were able to protect seed germination that have been grown in a Petri dish contaminated with P. ultimum and R. solani comparing with control. In addition, results indicated that spraying C. sativus and C. annum seedling with these algal extracts within two weeks old again protects these seedlings from the same phytopathogenic fungi either before or after 24 hr. However, results indicated that adding the algal extracts within two months age to the C. sativus and C. annum plants again protects these plants from the same phytopathogenic fungi comparing with control and fungicide treatment. Moreover, results indicated that the active chemical compounds in E. ralfsii was Tannins, Saponins and Flavonoids. While C. glomerata was contained Tannins, Saponins, Alkaloid and Phenols. Results indicated that both hot crud methanolic extract of C. glomerata (R) and E. ralfsii have a lot of active chemical compounds against micro - organisms by using the GC - Mass Spectrometry technology.

التاثيرات الفسلجية والكيموحيوية لعدد من المستخلصات النباتية في الدم والجهاز التناسلي الذكري في الجرذان البيض Rattus norvegicus المعرضة للكرب التاكسدي A Study of Physiological And Biochemical Effects of Plant Extracts on Blood And Male Reproductive System of Albino Male Rats (Rattus Norvegicus) Exposed To Oxidative Stress

اسم المؤلف: صاحب جمعة عبد الرحمن
اسم المشرف: زيد محمد مبارك المهداوي صالح محمد رحيم العبيدي
الموضوع العام: علوم الحياة
السنة: 2008
الموضوع الدقيق: الحيوان
الدرجة: دكتوراه
اللغة: العربية
مكان الجامعة: صلاح الدين
الصفحات الاولى:
المستخلص: تضمنت الدراسة الحالية معرفة بعض التاثيرات الفسلجية والكيموحيوية للمستخلصات المائية للكرفس (Apium graveolensL) والجرجير(Eruca sativa Mill) والطماطم (Lycopersicon esculentum Mill) في الدم والجهاز التناسلي لذكور الجرذان البيض المعرضة للاجهاد التاكسدي المستحد | The aim of the present study was to investigate some physiological and biochemical effects of the aqueous extract of celery (Apium graveolens L.), gardeen rocket (Eruca sativa Mill) and tomato frait (Lycopersicon esculentum Mill) on blood and male reproductive so system of Albino rats (Rattus norvegicus) exposed to oxidative stress induced by hydrogen peroxide 0.5% with drinking water for 21 days using vitamin E, as well known antioxidant as criterion for comparison. For the purpose of this study, preliminary experiments were carried out to find the most effective doses of plant extracts and it was found that these doses were 100, 150, 250 mg/kg body weight for, tomato, celery and gordeen roket extracts respectively. Fifty rats (12 - 14 weeks age) were randomly divided to ten groups (treatments) each with five replicates.These groups are : Group (1) (control group) : Rats without any treatment.Group (2) : Rats treated with H2O2.Group (3) : Rats treated with celery extract (150 mg/kg b.w.).Group (4) : Rats treated with celery extract (150 mg/kg b.w.) and H2O2.Group (5) : Rats treated with Eruca extract (250 mg/kg b.w.).Group (6) : Rats treated with Eruca extract (250 mg/kg b.w.) and H2O2.Group (7) : Rats treated with tomato extract (100 mg/kg b.w.)Group (8) : Rats treated with tomato extract (100 mg/kg b.w.) and H2O2.Group (9) : Rats treated with vitamin E (500 mg/kg b.w.).Group (10) : Rats treated with vitamin E (500 mg/kg b.w.) and H2O2 Results could be summarized as follow : 1. Compared with the control, the oxidative stress induced by H2O2 caused significant increase in total count of leukocytes, neutrophilis, acidophils, basophilis, monocytes and lymphocytes, and in the level of blood sugar (glucose), Total cholesterol, triglycerides(TG), low density lipoprotein (LDL - C), very low density lipoprotein (VLDL - C) atherogenic index (First and second), Urea, Malondialdehyde (MDA) and percentages of dead sperms and abnormal sperms.This stress showed as well, a significant decrease in body weight, Hb, PCV, high density lipoprotein (HDL - C), total protein, Albumin, glutathione, sperm total number, percentages of motile and normal sperms, testes weight, prostate and epididymis weights and seminiferous tubules diameter. This treatments, however, showed no significant variations in activity levels of ALT and AST enzymes and seminal vesicle weight.2. In comparison with treatment (2) (rats treated only with H2O2) , the treatment of rats, under oxidative stress with celery extract showed a significant decrease in total count of leukocytes neutrophils, lymphocytes and in blood suger, cholesterol TG atherogenic (First index) blood urea, MDA, Percentage of dead and abnormal sperms and seminal vesicle weight.This treatment showed also a significant increase in level of Hb, PCV., body weight, total protein, Albumin glutathione, number of sperm, percentages of motile and normal sperms, testis weight, epididymis weight and prostate weight. However no significant variations were detected in levels of acidophils, basophils, monocytes, HDL - C, atherogenic (second index) and seminituferous tubules diameter.3. Treatment of Eruca extract and compared with the treatment of H2O2, showed significant decrease in lymphocytes number and in the level of blood sugar, cholesterol (T.G), LDL - C, VLDL - C and atherogenic (first and second index) blood urea, MDA, percentage of dead and abnormal sperms and seminal vesicles weight. The treatment showed also a significant increase in body weight, numbers of acidophils, monocytes, basophils, HDL total sperm numbers, percentages of motil and normal sperms and weights of testis, epididymis and prostate.However, no significant variations were observed in Hb, PCV, Leukocyte total counts, neutrophil, albumin, ATL and AST and seminiferous tubule diameter.4. The treatment of tomato extract showed similar results to that of celary and Eruca extracts except, a significant increase in AST enzyme and seminiferous tubules diameter was detected in case of tomato extract (i.e not seen in case of other plant extracts).5. Compare with H2O2 treatment, rats under oxidative stress treated with vitamin E (500 mg/kg b.w) showed significant decrease in lymphocyte numbers, Total cholesterol, TG, LDL - C, VLDL - C, atherogenic (first and second index), urea, MDA and percentages of dead and abnormal sperms.At the same time the vitamin E treatment showed a significant increase in body weight , Hb, neutrophils, acidophils , monocytes, total protein, glutathione, total sperms number, percentage of motile and normal sperms, and weights of testis, epididymis, and prostate.However, this treatment (compared with H2O2 treatment) showed no significant difference in the level of PCV total count of leukocytes, basophils, blood sugar, HDL - C, albumin, ALT, AST, seminal vesicle weight and seminiferous tubules diameter 6. The most important histological changes exhibited by the animals under oxidative stress were apparent interstitial degeneration, necrosis of supporting and spermagonial cells, separation of these cells in semicyclic manner from the basement membrane, decrease in spermatids (spermatoblasts) and mature sperms in seminiferrous tubule cavity.These effects (due to H2O2 treatment) were decreased to minimal levels when the H2O2 treated rats exposed to plant extracts and vitamin E, used in this study.7. Animals treated with plant extract or vitamin E alone (i.e not treated before with H2O2) showed no clear difference from the control animal (without any treatment) though some improvement was observed in some physiological, biochemical and histological characters of blood and male reproductive system of the studied animals The above results revealed that the plant extract used in this study play an important role in decreasing the harmful effect of the free radicals in the animals (rats) studied.

دراسة جزيئية ومناعية لطفيلي اللشمانيا الجلدية Cutaneous Leishmania في المحافظات الوسطى والجنوبية Molecular And Immunological Study of Cutaneous Leishmania In The Middle And Southern Provinces

اسم المؤلف: ازهار موسى جعفر الموسوي
اسم المشرف: علي حسين الكبيسي مهدي حسين العمار
الموضوع العام: علوم الحياة
السنة: 2015
الموضوع الدقيق: علوم الحياة
الدرجة: دكتوراه
اللغة: العربية
مكان الجامعة: كربلاء
الصفحات الاولى:
المستخلص: The study includes distribution of the Cutaneous Leishmania in some governorates in Iraq. Specimens are included cases of outpatients in hospitals like : Al - Karamah, Al - Sadir Teaching Hospital in Baghdad, Al - Hilla Teaching Hospital, Al - Hussein Teaching Hospital and Ein Altamer General Hospitals in Kerbala, Al - Sadir Teaching Hospital in Al - Najaf, Al - Karamah and Al - Zahraa Teaching Hospitals in Wasit, Al - Diwanyia General Hospital. Al - Hussein General Hospital in Al - Nasiriya, Al - Smawa General Hospital, Al - Sadir Teaching Hospital and Al - Qurna General Hospital in Al - Basrah during October 1122 to march 1121 Cutaneous Leishmania is consider a major problem that faces the patients because it causes deformities in the infection region. The study includes 330 cases of skin ulcer in which 225 of them were microscopically positive. Parasitic growth was done using two types of cultural media NNN and RPMI - 1640.The results have shown a considerable difference between male and female in which male was significantly exceeding 131) %22.11 (and female was 94) %72.44 (and 139) %72.44 (of outpatients from rural areas increased in numbers from outpatients of urban areas, and only) %12.11(from urban areas.The number of ulcerations in body has exceeded infection, that means more than one ulceration in male 83 (85%) and for female 41 (62%), and concerning infection in three or four ulceration, it is approximately equal and normally distributed on face areas 99 and a percentage of (44%) then lower arms are 92 and a percentage of (40.80%) and the upper parts are 33 and a percentage of (14.66%). Also, one infection was recorded on The study shows that 46 patients in a percentage of (%20.44) having a dry infection; whereas 179 patients (%79.55) having the wet type.For accurate diagnosis of Leishmaniaa species distributed in Iraq, PCR Was used technique and diagnosed two types of Leishmania parasite that causes the illness. A band in a length of 560 bp in 186 samples related to Leishmania major and the band sample was 750 bp related to 39 Leishmania tropica.Through studying the samples in Kerbala City, the number infected samples were 125 for the years of 2010 - 2011 the actuality is (73) infection and (52) infection from 2011 - 2012 in a ratio of (58.4 % and % 72.7 accordingly) in different inhibited areas in the governorate in which (51)) %71.2 (was in Ein Al - Tamir Suburb, and 29 cases of) %11.1 (in Al - Husseinya Suburb, as well as 17 cases of (13.6%) in Al - Hur Suburb, 16 cases) %21.2 (in the south quarters and 7 cases of (5.6%) in the north quarters and only 5 cases of (4%) in the city center.The molecular diagnosis in Polymerase Chain Reaction for Kerbala governorate samples have shown 31) %17.2 (of L.tropica, 22) %24.7(of them were male and 9 of) %4.1 (of them were female. L. major was 94 of) %42.1 (in which 55 of) %77 (were in male and 39 of) %12.1 (were in female.The immunological study for the patients serums with L. major by ELISA technique has significantly shown raised values of IgG and IgM during infection in comparison with the control group, then it declines slowly after treatment in which IgG was in ratio (1811.1 ± 523.1 mg/dl), and IgM was in ratio (166.7 ±23.6 mg/dl). Also, in L. tropica - IgG was in ratio (1722.1 ± 524.0mg/dl) and IgM was in ratio (25.3±182.9mg/dl) in comparison with control specimens, and then the ratios have declined after treatment dosages with Pentostam drug.The cellular dynamics values have shown an abstract increase in which interferon - gamma (IFN - ?) in infected patients with cutaneous L. major were (221.1±2.2mg/dl) which declined after treatment abstractly to (7.12±1.1mg/dl) as well as for L tropica (22.1±7.2mg/dl) which shows no significant abstract difference after treatment with control.An increase appears in cytokine IL - 10 that reached in L.major (122.1±8.2mg/dl) and after treatment was (8.11±2.2mg/dl) and in L. tropica was (222.1±2.2mg/dl) with no significant abstract difference after treatment with control specimen.As a simple attempt to find a vaccine for Leishmania disease a Lipophosphoglycan was isolated and purified as known factor for promastigot stage. The vaccine injected for two groups of Bulb mice in a concentration of purified vaccine (L.majorand Ltropica) to study the immunological response by detecting the Lymphocyte Transformation assay, the Delayed Type Hypersensitivity test and the PhagocytosisIndex.In lymphocyte transformation the ratio of L. tropica was % 7.2 and for L. major was % 21.7 and there is significant difference by P? 0.05 in comparison with control specimen in which its ratio was %7.4, and for Delayed Hypersensitivity test study the average foot thickness injected with vaccine and the other foot which injected with phenol - saline solution - only (1.11 ± 2.12ml) for the first group and (1.21 ± 2.72) for the second group, and for the control group it has registered (1.77± 1.15 ml) with a considerable difference of P? 0.05. By calculating the ratio of Phagocytosis Index cells, it was 17% and 27.6% for the first and second groups while for the control group it has been reaching 9.10%. Therefore, we can get advantage from these values as indicators for the rule of vaccine in the immunological response and triggering of vaccine idea for this disease.

عزل وتشخيص البكتريا العنقودية السالبة لانزيم الخثرة من حالات مرضية مختلفة ودراسة مقاومتها للمضادات الحيوية Isolation And Identification of Coagulase Negative Staphylococci From Different Clinical Cases And Study of Their Antibiotic Resistance

اسم المؤلف: مجاهد خلف علي احمد الجميلي
اسم المشرف: عباس علي هادي الدجيلي وعد محمود رؤوف
الموضوع العام: علوم الحياة
السنة: 2008
الموضوع الدقيق: التقنيات الاحيائية
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: صلاح الدين
الصفحات الاولى:
المستخلص: جمعت 265 عينة من مستشفى تكريت التعليمي العام وشملت هذه العينات عينات سريرية لمرضى راقدين في المستشفى ومرضى مراجعين لها. اخذت العينات من المرضى المشتبه باصابتهم بخمج السبيل البولي وخمج الجروح والحروق وخمج الاذن الوسطى ولكلا الجنسين وباعمار مختلفة. انجزت هذ | A number of 265 samples had been collected from Tikrit Teaching Hospital (T.T.H.).These samples were taken from inpatients and outpatients suspected to have Urinary Tract Infection, Wound & Burn Infections and Mid - Ear infection for males and females in varied ages. The practical part had been fulfilled during the period from the beginning of December 2006 till the beginning of March 2007.Isolates diagnosed were identified depending on morphological and cultural characteristics. The results revealed 60 Staphylococci isolates, which shows 27 isolates (45%) were S. epidermidis, 13 isolates (21.66%) S. saprophyticus, 10 isolates (16.67%) S. xylosus, 3 isolates (5%) S. lentus, two isolates (3.33%) S. heamolyticus, and one isolate (1.67%) for each of S. simulans and S. hominis Ten (34.48%) of patients are located in the age group (15 - 30) years. while concerning the classification according to sex, females were (65.5%). Otitis media and Wounds and Burns infections, their ratio was high (61.1%, 53.8%) consequently both in males in comparison with females. Concerning the relationship between the infection and the residence and the level of education, the results revealed that isolation of Coagulase Negative Staphylococci (CoNS) were high in rural areas and in uneducated persons regarding the various infections than those live in urbans and educated ones. A of main tests were carried out in order to achieve the purpose of this study according to the planned goals, some of which are the virulence factors of Coagulase negative Staphylococci. These include DNase, Urease, Lipase, Lecithinase, and Alkaline phosphatase.The results revealed the ability of 67.5% of isolates to produce Alkaline phosphatase, and 46.6% of isolates to produce Urease, also 27.5% of isolates were able to produce Lecithinase , and the ability of 19.16% to produce Lipase, while 22.5% of isolates were capable of producing DNase. In addition to these tests, the test for producing ? - lactamase was done, 85% of isolates were positive to this test because ? - lactamase is one of the significant enzyme which are produced by bacteria since it improves the resistance of bacteria for antibiotics. Thirteen different antibiotics used for the Antibiotics susceptibility tests which show that most effective antibiotic is Nitrofurantoin (95%), followed by Amikacin (93.3%), Novobiocin(90%), Chloramphenicol(88.3%), Rifampicin (78.5%), Vancomycin (75%), Ciprofloxacin (73.3%), Clindamycin (70%), Gentamicin (58%), Penicillin G (50%), Trimethoprim (50%), Tetracycline (40%) and Cefoxitin (18.3%).

تقييم خليط الكيتامين والترامادول والباراسيتامول والزايلازين كبرامج للتخدير العام بالحقن في الاغنام Evaluating of Ketamine, Tramadol, Paracetamol And Xylazine Combination As An Injectable General Anesthetic Protocols In Sheep

اسم المؤلف: علي اسماعيل جاسم
اسم المشرف: ثاير علوان عبد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الجراحة
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: هدفت الدراسة الى تقييم استخدام الكيتامين (K)، والترامادول (T)، والباراسيتامول (P) والزيلازين (X) كبرامج تخدير للاغنام باستخدام جرعات مختلفة وطرق اعطاء مختلفة. استخدم في التجربة ثلاثون من الاغنام الكبار البالغة من السلالة المحلية (تراوحت معدل اوزانها 27.4 | The study aim to evaluate the use of ketamine (K), tramadol (T), paracetamol (P) and xylazine (X) as an anesthetic protocol for anesthesia in sheep by using different doses and different routes of administration. Thirty animals of adult local breed sheep weighing (27.4±2.46) kg were used in 6 different anesthetic protocols. The animals were divided into six groups (5 animals of each). The first three groups (without using of xylazine) were giving the drugs by IV injection in the jugular vein : G1 giving K4 and P10 mg/kg IV, G2 giving K4T2 mg/kg IV, and G3 giving K4 T2 P10 IV. In the other groups (G4, G5, and G6) xylazine were adding to the anesthetic protocol. G4 giving K4 T2 P10 X0.05 by IV route. G5 was giving K10 T2 P10 X1 mg/kg by IM route and G6 giving K20 T4 P10 X2.5 mg/kg by IM route. The HR, RR, RT, muscle relaxation, limb, and flank analgesia, and rumen movement were taken before administration of anesthesia (time 0) and consider as the control reading. Then taken at 5, 10, 15, 20, 30, 45 and 60 minutes or till the end of anesthesia. In the IV groups (without using of xylazine), (G1, G2, and G3). The induction time was 53.2, 60, and 68 seconds, the surgical anesthesia was 2.8, 5, and 5 minutes, and the total recovery time was 4.8, 5.4, and 3 minutes in G1, G2 and G3 respectivily. The RR, and HR were increased, and the RT was decreased. The muscle relaxation was mild, and the analgesia was moderate. In G4 after adding of xylazine and giving the anesthetic protocol by IV route, the induction time, the surgical anesthesia, and the total recovery time were become 50.6 seconds, 23 minutes, and 9.4 minutes respectively. The HR, RR, and RT were increased, the muscle relaxation, and analgesia were moderate. In G5 after increased the dose of ketamine and xylazine and giving the anesthetic protocol by IM route, the induction time, the surgical anesthesia, and the total recovery time were 5, 36, and 5.6 minutes respectively. The HR and RR were decreased, and the RT was increased. The muscle relaxation was deep for 10 minutes, and the analgesia was moderate for 10 minutes also. In G6 after doubling the ketamine, tramadol, and xylazine doses, and giving the anesthetic protocol by IM route. The induction time, the surgical anesthesia, and the total recovery time were 3.6, 73.4, and 7 minutes respectively. The HR started stable, then after 15 minutes decreased sharply, The RR was irregular, with apnea, the RT was increased, the muscle relaxation was deep for 35 minutes, and the analgesia was deep for 45 minutes. In conclusion the addition of tramadol and paracetamol to the ketamine anesthesia of sheep in low doses, improve the induction and recovery time of anesthesia, without increase the duration and depth of anesthesia. Adding of xylazine to the anesthetic protocols increase the duration and depth of anesthesia. The protocol of K10 T2 P10 X1 by the IM route is the best protocol dose among the six protocols used in this study.

تاثير فيتامين E والسلنيوم على الجرذان المحقونة بالذيفان الداخلي لجراثيم Salmonella typhimurium Effect of Vitamin E And Selenium On Rats That Injected With Salmonella Typhimurium Endotoxin

اسم المؤلف: زينة حمزة جعفر
اسم المشرف: جبار عباس احمد الساعدي محسن عبد نعمة الروضان
الموضوع العام: الطب البيطري
السنة: 2010
الموضوع الدقيق: الطب الباطني والوقائي
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: صممت الدراسة الحالية بهدف تحديد التاثيرات الفسلجية والمناعية والنسجية المرضية التي تسببها الذيفان الداخلي لجرثومة Salmonella typhimurium وتداخل فيتامين E والسلنيوم في تقليل تاثيراتها السمية في اعضاء الجسم وتعزيز فعالية الجهاز المناعي لذكور الجرذان البيض. | The present study has been designed to determine the physiological, biochemical, immunological and histopathological effects of endotoxin of Salmonella typhimurium and the interaction of vitamin E and selenium in releifing its toxic effects on body organs, as well as its immuno - modulatory effect in mature male ratsForty mature male rats, nearly similar in their weight and age, were randomly divided into four equal groups : First group (control) rats were injected with normal physiological saline (0.5 cc ip) and 2nd group (T1) have been given the ration drinking water and injected with endotoxin intrapretonealy with dose 0.5 mg/kg bw for 18 days while (T2) and (T3) groups were treated by vitamin E with a dose of 30 mg/kg bw and selenium with a dose of 2.8 ppm/kg bw) for 30 days. (T2) was injected at thirty one day by endotoxin at a dose 0.5 mg/kg bw intrapretonealy for 8 days. Public health parameters like body weight, blood parameters (RBC count, PCV, total WBC count and differential leucocytes count, AST and ALT concentration) Phagocytosis activity for neutrophil and monocytes. Immunoglobulins (IgA, IgM and IgG) estimation, gross and histopath - ological changes and clinical sings were included in the present study.The results revealed that endotoxin injection led to different changes, its significancy flactuated according to the type of studied parameter, as follow : The results of clinical sings of experimental animals revealed occurrence of excitation after 10 minutes of injection, sever dullness, loss of appetite, muscular weakness, lateral recumbency in addition of loss of weight and easily handle. Significant decrease (P<0.05) of body weight, RBC count, ,PCV and monocytes percentage. Significant increase (P<0.05) of total WBC count and percentage of neutrophil, lymphocytes, eosinophil, and AST, ALT, IgM and IgA concentrations and no significant difference of IgG concentration. Significant decrease (P<0.05) of phagocytic activity.Gross pathological changes represented by the presence of necrotic and hemorrhagic foci, clotting as well as congestion and enlargement of liver, kidneys, lungs, spleen and heart. The histopathological appearance revealed by vaculation, necrotic and degenerative changes of hepatocytes in live, the spleen showed many changes led to imbalance between white and red bulb spaces, the heart showed lack of cross striation, edema between cardiac muscle fibers, while lungs showed an emphysema and sever hyperplasia in the bronchial epithelium. From other hand, the results showed that receiving vitamin E and selenium had an efficient effect for the improving the toxic effects of endotoxin and relieving its toxicological changes in the animal organs as compare with group that injected with endotoxin only, this group shows slight clinical signs and increase of appetite and drinking of water, improvement of blood parameters and reduce in the concentration of ALT and AST in blood serum, also there was increase in the phagocytic activity and increase in the levels of IgM, IgA and IgG. The gross pathological cganges less sever as compare with T1. It can be concluded that exposure to Salmonella typhimurium endotoxin leads to many distinct toxic effects on different organs and systems of the body which may results in many physiological disturbances. This study, also, proved that vitamin E and selenium have an important efficient role in improving the toxicological changes resulted from endotoxin poisoning.

دراسة نسجية ,كيمو نسجية وكيمو حيوية لتاثير عقار الكودائين - باراسيتامول في ذكور الجرذان المختبرية Histological, Histochemical And Biochemical Study of The Effects of Codeine - Paracetamol In Male Sprague Dawley Rats

اسم المؤلف: اسيل كامل حميد الهاشمي
اسم المشرف: عادل جبار حسين صالح كاظم مجيد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: التشريح والانسجة والاجنة
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: صممت هذه الدراسة لمعرفة التاثيرات النسجية, الكيمونسجية والكيموحيوية للاستخدام طويل الامد لعقار الكودائين - باراسيتامول على الجرذان المختبرية, حيث استخدمت في هذه الدراسة اربع وعشرون جرذ ذكر (وزن الحيوانات 200غم) قسمت عشوائيا وبالتساوي على اربع مجاميع. احتو | The present study is performed to evaluate the histological, histochemical and biochemical effects of long term use of codeine - paracetamol drug on laboratory rats, this study performed in college of veterinary medicine at university of Basra, there was (24) male rats(Body weight 200g) were divided randomly and equally into four groups, each group consisted of six rats for which codeine - paracetamol drug was orally administered for (90) days as the following : for group (A) normal saline was administered and it served as a control group. Group (B)was administered with (8/500 mg/200g) and served as low dose group, group (C)was administered with (16/1000 mg/200g) and served as intermediate dose group, and group (D) was administered with (32/2000 mg/200g) and served as high dose group. The statistical analysis results of body weight of the long term use of drug for the treated groups showed significant decreases (P?0.05) of body weight of both(L.D) and (H.D) while the (I.D) showed no significant (P?0.05) difference when compared to the control group. The internal organs weight (liver, kidney and spleen) showed significant decreases (P?0.05) of liver weights in both (L.D) and (I.D), while the (H.D) showed no significant difference of liver weight when compared to the control group; the kidney weight showed significant increases in both (L.D) and (I.D), while the (H.D) showed no significant difference when compared to the control group. Spleen weight also showed a significant increase in both (L.D) and (I.D), while the (H.D) showed significant decrease when compared to the control group. The serum lipid profile showed significant increases (P?0.05) in the levels of (cholesterol, triglyceride, High Density Lipo - protein and Low Density Lipo - protein) and no significant difference of (Very Low Density Lipo - protein) of (L.D), while the (I.D) showed significant increases of the levels of (cholesterol, HDL and LDL) and no significant differences of the levels of (triglyceride and VLDL), (H.D) also showed significant increases of levels of (cholesterol, triglyceride, HDL, LDL and VLDL) when compared to the control group. The statistical analysis of the results of liver and kidney function enzymes showed no significant differences of total serum bilirubin (TSB) of both (L.D) and (I.D) and a significant increase in (H.D); There was no significant (P?0.05) differences in the level of serum direct bilirubin (D.B) among all treated groups when compared to the control group , while the (H.D) group there was non significant compared with control and other treated groups, while the levels of (Aspartate Aminotransferase AST , Alanine Aminotransferase ALT, Alkaline phosphatase ALP and creatinine) showed significant increases in all treated groups when compared to the control group. Histological results of the liver of (L.D) and (I.D) showed vacuolation of hepatocytes and dilatation of sinusoids in which the vaculation is more severe in (I.D) with early septal fibrosis, while the liver of (H.D) showed severe centrolobular necrosis, hemorrhage, dilation of sinusoids and septal fibrosis. While the kidney of (L.D)and (I.D) showed vaculation of proximal convoluted tubules and glomerular mesengial cells with minimal vacuolation in (L.D), The kidney of (H.D) showed necrosis and vaculation of proximal convoluted tubules with vaculation of glomerular mesengial cells. The nervous system (brain, spinal cord and sciatic nerve) of all treated groups showed vacuolation of nerves cells and axons, severe vacuolation in (H.D). The lung showed edema and aggregation of inflammatory cells in lung of both (L.D) and (I.D) while the lung of (H.D) showed severe edema, enlarged proliferative and aggregation of lipid laden macrophages (pulmonary lipidosis). While the heart showed mild vacuolation of myocardial muscle cells of both (L.D) and (I.D), but the (H.D) showed sever vacuolation of myocardial muscle cells. The stomach also showed mild vacuolation of gastric epithelium in all treated groups. The testes also showed vacuolation and suppression of spermatogenesis in the (L.D) and moderate vacuolation and suppression of spermatogenesis in (I.D) while (H.D) showed present of giant multinucleated spermatid with sever vacuolation and suppression of spermatogenesis. While the spleen showed mild to moderate atrophy of white pulps of the (L.D) and (I.D), (H.D) also showed severe atrophy of white pulp with mild fibrosis and the presence of hemosiderin laden macrophages and foamy vacuolated macrophages. The histochemical study of poly saccharides(glycogen) of liver and kidney showed decrease of poly saccharides composition in mid zonal area and near the central vein, while in kidney, it was present in proximal convoluted tubules and in bowman's capsules in the (L.D) and (I.D), those changes were more severe in (H.D). While the histochemical study of lipid showed increase of lipid composition in hepatocytes near the central vein and in kidney in the proximal convoluted tubules and bowman's capsules, and those lipid compositions increased when the dose increased. The electron microscope study of liver showed mild to moderate swelling of mitochondria and dilation of smooth endoplasmic reticulum in both (L.D) and (I.D), while (H.D) showed severe swelling of mitochondria and dilatation with proliferation of smooth endoplasmic reticulum.

دراسة تاثير بعض الاضافات على الاستجابة المناعية ووزن الجسم والتغيرات النسجية لفروج اللحم الملقح بلقاح مرض النيوكاسل A Study The Effect of Some Additives On Immune Response And Body Weight And Histological Changes For Broiler Chicks Vaccinated With Newcastle Disease Vaccine

اسم المؤلف: هبة تركي عطية الرماحي
اسم المشرف: نافع صبيح جاسم
الموضوع العام: الطب البيطري
السنة: 2015
الموضوع الدقيق: الامراض - الدواجن
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت? هذه الدراسة لمعرفة تاثير بعض الاضافات في الاستجابة المناعية والوزن والتغيرات النسجية في الامعاء الدقيقة. حيث تم تقسيم (350) طيرا من فروج اللحم بعمر يوم واحد من نوع Ross 308) ) غير مجنسة , وزعت عشوائيا الى (7) معاملات تغذوية متساوية وهذه المعامل | This study was conducted to investigate the effects of feed additives on immune response , weight and histological changes in small intestine. A total of (350) broiler chicks one - day old (Ross 380) - unsexed were randomly divided in to (7) equal dietary treatment groups , as fallows : Treatment (T1) : Basal diet without any addition ( control group).Treatment (T2) : Basal diet + Garlic 4cc/10 LTreatment (T3) : Basal diet + Saccharomyces cervisiae 2.5gm/10 L.Treatment (T4) : Basal diet +Stpire 2.5cc/10 L.Treatment (T5) : Basal diet +B. glucan 8gm/10 kgTreatment (T6) : Basal diet + Levamisole 1gm/kg.Treatment (T7) : Basal diet + Neomycin 0.5 gm/L.These additions were presented on the first day of the arrival for 5 days, and on the day of first vaccination for 5 days and at the end of experiment for 5 days also. This chicks vaccinated with NDV on the day one of age by injection in the neck and re - vaccinated at day 10 of age with LaSota, Body weight were weekly determined. ,blood samples were collected from wing vein for ELISA test in ( 4,18,27 ) days old respectively. The results as following : - 1 - Treatment of levamisole (T6) were significantly increased ( p<0.05) in (T2, T5) in level of Abs production against ND virus.2 - Chicks feed diet with saccharomyces cerevisiae showed significantly increased ( p<0.05) in body weight among all experimental group , and improvement in weight in (T6,T7) with other group.3 - Chicks feed diet with (T7) showed improvement in villus hight and in the ( T3, T4).

دراسة التاثير العلاجي لحليب الافراس المخمر للتقليل من تاثير الاجهاد التاكسدي المستحدث بواسطة خلات الرصاص في الجرذان البيض Study The Therapeutic Effect of Fermented Mare? S Milk To Reduce The Effect of Oxidative Stress Induced By Lead Acetate In White Albino Rats

اسم المؤلف: شيماء عباس صبيح
اسم المشرف: كريم ناصر طاهر
الموضوع العام: الطب البيطري
السنة: 2015
الموضوع الدقيق: الصحة العامة
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية في البيت الحيواني التابع لكلية الطب البيطري / جامعة القادسية بهدف تقييم الدور العلاجي لحليب الافراس المخمر في التقليل من تاثير الاجهاد التاكسدي المستحدث بواسطة خلات الرصاص. استخدم في هذه الدراسة ( 40 ) ذكر من الجرذان البيضاء نوع ( w | The present study was conducted at the animal house of veterinary medicine college of AL - Qadisiyah University during the period from 27 - 2 - 2014 to 30 - 3 - 2014. to evaluate the productive role of fermented mare's milk in to reduce the oxidative stress that induced by lead acetate , 40 male albino rats weighing between 200 - 210 gm were used in this study. the animals were obtained from the animal house of veterinary medicine College / Baghdad University. The animals were randomly distributed into four equal groups , ( 10 rats per each group / cage) as follow : - Control group : The rats were given only basal diet and deionized drinking water - - First treatment group ( T1) : The rats were given basal diet and deionized drinking water that contain 1000 ppm lead acetate for 30 days. - Second treatment group ( T2 ) : The rats were administrated basal diet and deionized drinking water that contained 1000 ppm of lead acetate and received orally ( by gavag ) fermented mare's milk at a dose ( 10ml / kg b.w / day ) for 30 days. - Third treatment group (T3) : The rats were given basal diet and deionized drinking water that contained 1000 ppm of lead acetate and received orally ( by gavag ) EDTA at a dose ( 50 mg/ kg b.w / day ) for 30 days. At the end of the experiment all the animals were fasted for ( 12 hours ) and then killed animals from each treatment group blood samples were collected from the heart to measures some blood parameters such RBC , Hb and PCV and biochemical parameters such as liver function parameters ( total protein and activity of some enzymes such as ALT , AST , ALP and LDH ) , kidney function parameters such as Urea and Creatinine concentration and oxidative stress parameters such as GSH , SOD , MDA ). In addition to that study the histopathological changes of liver and kidney tissues were studied The results of the present study can be summarized as follow : - 1 - Blood parameters : The results of the statistical analysis showed that there was a significant ( p < 0.05 ) decrease in the mean values of RBC , Hb , and PCV in a group treated with lead acetate only ( T1 ) as compared to other experimental groups. while groups treated with EDTA and fermented mares milk showed a significant ( p < 0.05 ) improvement in blood parameters. 2 - Biochemical parameters : A - Liver function parameters : The result revealed that there was a significant ( p < 0.05 )effect of lead acetate on level of total protein where caused a decrease in total protein concentration and increase the in activity of ALT , AST , ALP , and LDH as compared to other experimental groups. Yet treatment with fermented mare's milk ( T2 ) resulted in an increase in the total protein concentration and a decrease in the activity ALT , AST , ALP AND LDH. Also treatment with EDTA ( T3 ) caused a similar results to ( T2 ). B - Kidney function parameters : The results obtained in this study demonstrated that a significant ( p < 0.05 ) increase in the level of urea and creatinine in a group of animals treated with lead acetate only ( T1) , while using fermented mare's milk ( T2 ) and also EDTA contributed reduction in the level of urea and creatinine 3 - Oxidative stress parameters : The results of the present study showed that there was a significant ( p < 0.05) decrease in the concentration of GSH and SOD a significant ( p < 0.05 ) increase in MDA concentration in animals that administrated lead acetate only ( T1) while administration fermented mare's milk and EDTA resulted in significant ( p < 0.05 ) increase in the concentration of GSH and SOD while a significant ( p < 0.05 ) reduction in MDA concentration. The values becomes close to the concentration of the control group. 4 - Histopathological changes : The results of Histopathological examination for tissues of liver and kidney of rats given lead acetate alone ( T1 ) showed that there was a clear Histopathological changes presented in degeneration of hepatocytes and congestion in central vein which associated with hemorrhage in liver and kidney tissues of animals administrated fermented mare's milk showed normal and free from congestion.

عزل وتشخيص النمط المصلي O78 : K80 لاشريشيا القولون الممرضة للطيور من دجاج اللحم ودراسة اصابتها تجريبيا Isolation And Identification of Avian Pathogenic E. Coli O78 : K80 Serotype From Broilers And Study of Its Experemintal Infection

اسم المؤلف: رجاء عبد الزهرة علي
اسم المشرف: علي عبد سهم المياح
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الامراض - الدواجن
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: الايشريشيات القولونية مسئولة عن احداث حالات مرضية مختلفة تسبب خسائر اقتصادية ناتجة عن الهلاكات العالية وانخفاض معدل التحويل الغذائي والخسائر في اتلاف الجثث والاعضاء المصابة بعد الذبح.تم في الدراسة الحالية فحص 70عينة من افراخ فروج اللحم الهالكة او التي كا | Escherichia coli (E. coli) is responsible for a variety of diseases conditions which cause high economic losses in poultry due to high mortalities, decreased food conservation rate and condemnation of whole affected carcass or organs after slaughter. In the present study, 50 out of 70 broiler chickens which have been collected from diseased chickens were exhibited lesions of fibrinous perihepatitis, fibrinous pericarditis and/or airsacculitis. Birds with these lesions were subjected for bacteriological examination. The examination revealed isolation of 23 E. coli isolates with incidence of 46%. Concerning the virulence factors , Congo red binding activity of these isolates reveled detection of 6 positive isolates with incidence of 26.08%. Serotyping showed that out of 6 Congo red positive strains, only 3 strains were serologically typed and were belonged to the serotype O78 : K80. Detection of pathogenic E. coli serotypes was confirmed by PCR technique with specific primers for fimA and fimH genes. All these 3 isolates of the serotype O78 : K80 were reacted with these 2 genes. Antimicrobial suscebtibility pattern displayed sensitivity of these isolates to Chloramphinicol and Gentamicin and their resistance to Amoxicillin, Erythromycin and Nalidixic acid. Experimental infection has been made with this isolate. Two groups of broiler chickens were used the first at one day old and the second at 5 weeks of age. Signs, lesions, histopathological changes were revealed that the first experiment was differed from the second through the presence of pus in the bursa of Fabricius, but hemorrhage in the lungs tissue occur in two experiments.

دراسة الاهمية الوقائية لحليب الماعز وتاثيراته في بعض الصفات الانتاجية والمناعية لاناث الارانب المعاملة بالمضاد الحيوي اموكسي كلافولانيك اسيد The Important Protective Study of Goat Milk And Its Effects On Some Productive And Immune Traits of Female Rabbits Treated With Amoxi - Clavulanic Acid

اسم المؤلف: حسين باعي خضر حسين الجياشي
اسم المشرف: كريم ناصر طاهر علاوي لعيبي داغر
الموضوع العام: الطب البيطري
السنة: 2012
الموضوع الدقيق: الصحة العامة
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: This study was carried out from 12 - 3 - 2011 to 29 - 4 - 2011 to find out the protective importance of goat milk and its effects on some productive traits ( body weight , weight gain , feed intake, and feed conversion efficiency) ,some immunological traits ( white blood cells , percent of lymphocyte cells) ,some biochemical traits (total serum protein , albumin ,globulin ) ,some physiological traits ( hemoglobin and Packed cell volume) in the rabbits treated with Amoxicillin - clavulanic acid.A total of (32) female rabbits (local breed) aged range between 2 - 3 months with average of initial body weight 1706.25 gm.were distributed randomly into four groups each one consist of eight rabbits as below : 1 - Control group ( C ) : Fed basal diet without any addition.2 - First treatment group ( T1 ) : Fed the same basal diet + 5 mg ? kg b.w. x 2 amoxi - clavulanic acid for one week3 - Second treatment group ( T2) : Fed the same basal diet +( 5 mg ? kg b.w. x 2 amoxi - clavulanic acid + 5ml x2 raw goat milk ) for one week.4 - Third treatment group ( T3 ) : Fed the same basal diet + 5ml x2 raw goat milk for one week.The experiment continued for five weeks in which each rabbit weight at weekly interval and the residual feed weighed daily ,The results revealed the following : - Treatment one showed signs of gastric ulcer ,diarrhea , small and large intestinal inflammation ,while T2 group ( antibiotic + goat milk ) did not show any signs of gastric ulcer, diarrhea and their digestive system normal like the control ( C ) and Treatment three ( T3 ) group ( goat milk ).Body weight of ( T3 ) group recorded significantly) P < 0.05 )increased as compared with body weight of T1 group in all study weeks. And recorded the highest body weight among the other study groups during all periods of the study weeks (1769.12, 1751.37,1795.00 , 1824.25 ,1852.75) gm respectively.Animals in group ( T3 ) exceeded in weekly body weight gain as compared with other treatment groups during the studied period except the second week ( 62.87, - 5.25, 32.5, 29.25 , 28.5) gm respectively.Treatment ( 1 ) showed decrease in weekly feed intake on the first 4 weeks of study ) 60 , 42.51 , 44.88 , 34.25 gm )respectively as compared with C and T3 groups.Treatment ( 3 ) showed that feed conversion efficiency means recorded better value during the fifth weeks of studied weeks and was ( 5.53 , - 64.30 , 10.79 , 11.98, 12.11) gm food ? gm gain respectively recorded.There are significant increases ) P < 0.05 ) in white blood cell means for C ( control ), T2 , T3 groups) 6.352, , 6.32 6.45) x 10 3 ? ?L. compare with the T1 group ( 4.772 x 10 3 ? ?L ) and also lymphocyte percentage means of T1 (38.95 % ) showed significant lower ) P < 0.05 ) compared with other treatment groups ( C , T2, T3 ) ( 55.05 , 54.80 , 57.07 ) respectively.The control and T3 groups showed significant) P < 0.05 ) exceeded in hemoglobin and packed cells volume as compared with T1 and T2 groups which there is no significant difference between them.Where the average of four treatment group control ,T1 ,T2, T3 record 44.837 , 38.675 , 38.825 , 44.800 respectively.Treatment 3 exceeded other treatment groups in the total protein ( 88.156 )gm/l and also T1 group showed significant ) P < 0.05 ) decrease in albumin ratio ( 26.682 ) gm/l, while T1 showed significantly ) P < 0.05 ) higher in their gamma globulin compared with other treatment groups.Treatment 3 and 1 groups showed significant ) P < 0.05 ) increase in liver relative weight as compared with the control and T2 groups and the liver relative weight means of the ( C ,T1 ,T2 ,T3 ) groups as followed respectively 2.64, 3.05, 2.53 , 3.08 %.

The Role of Cyclosporine In Intra Bone - Bone Marrow Transplantation In Male Rabbits

اسم المؤلف: عادل جاسب عويد
اسم المشرف: Abdulbari A. Alfaris Alaa A. AL Sawad
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الجراحة
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: استخدم فيها 30 ارنبا ذكرا حيث قسمت الى ثلاثة مجاميع متساوية بالعدد كل مجوعه تحوي على عشرة ارانب اثنان منها تم اختيارها كواهب لنخاع العظم والثمانيه الاخرى كانت مستلمه, وكانت المجموعه الاولى هي مجموعه سيطرة وقد اعطيت المحلول الملحي الطبيعي ,والمجموعه الث | Thirty male rabbits were randomly divided into three groups as following : Group one (sham group) consists of ten male rabbits, two of them were used as donors and other eight were administered 12.5ml/kg/BW normal saline (N.S) orally for ten days. At Zero time of the experimental the collection of blood samples (10ml) was carried out on each animal from the heart (cardiac puncture) and by a sterile syringe 22 Gage needle. The (10ml) amount of blood was divided into two parts. (5ml) was deposited into tubes without anticoagulant and then refrigerated for a maximum of 12h and centrifuged at (5000 rpm) for 15 minutes these serum samples were stored in polyethylene eppendorff tubes at - 20?C Estimation of Total interleukin 2 in serum by using an Enzyme - Linked Immunosorbent Assay (ELISA). The 2nd sample was also (5ml) taken for performing hematological test to measure the WBCs account and their differential, RBCs account, Hb & P.C.V. At Day10 of experimental was collecting the blood as similar procedure at zero time and did a similar examination before operation. At Day11 of the experimental an allogeneic Intra - bone - marrow injection of bone marrow transplantation aspiration method (IBM - BMT) AM was carried out and rabbits were re administered with normal saline after surgical operation until Day21 of experimental. Following that rabbits were anesthetized with Ketamine (20 mg/Kg/BW) and xylzine (9 mg/Kg/BW) intra muscular. Before bone aspiration for bone marrow histological test the smears were stained with Giemsa stain. At the end of this experimental study of there was collection of blood as a same procedure at zero time and DAY10 then made the same test to estimate of blood values and interleukin 2. Then all recipients’ rabbits were sacrificed and bled to death to obtain the Kidney and liver, which were dissected out, trimmed and processed for the histological study with used Heamatoxyline and Eosin Stain. Group two (treated with 12.5ml/kg/BW cyclosporine orally administrated) and same protocol of the sham group was applied except when using (treatment with 12.5ml/kg/bw cyclosporine orally administrated) replacing the normal saline. Group three (treatment with 25ml/kg/BW cyclosporine orally administrated) and same protocol of sham group was applied except when using (treated with 25ml/kg/BW cyclosporine orally administrated) replacing the normal saline. The results of the present study Conclusions cyclosporine effects on the bone marrow, immune system because of decrease of WBCs, lymphocytes, neutrophils and interleukin 2.The study Conclusions cyclosporine caused many adverse effects, where by it caused severe liver and kidney; therefore it was considered predisposing factor to infection with several diseases as well as it is considered the main cause of disorders in renal function renal dysfunction. The results of the present study Conclusion the surgical operation of intra - bone - bone marrow transplantation more safe than other ways of intra vinous bone marrow transplantation also the study the operation increase the hematopoietic cells

اسباب انخفاض الخصـوبة والعقـم في الافراس العراقية The Causes of Infertility And Sterility In Iraqi Mares

اسم المؤلف: سمير صبري كاظم الخفاجي
اسم المشرف: ضياء حسين جاسم الدليمي
الموضوع العام: الطب البيطري
السنة: 2013
الدرجة: دبلوم عالي
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اظهرت نتائج الدراسة الحالية ومن خلال مراجعة المصادر ان مشاكل الخصوبة والعقم في الافراس تتخلص بــ : اسباب خارجية تتعلق بعدم استخدام الافراس خلال الموسم التناسلي بسبب ظروف تصميمية او ظروف لايمكن تجنبها متمثلة بقصر موسم التناسل والولادات في وقت متاخر من الموس

دراسة مسببات عسر الولادة في الجاموس Etiological Study of Dystocia In Buffaloes

اسم المؤلف: مروة علي هادي الفياض
اسم المشرف: طاهر عبد الحسين فهد
الموضوع العام: الطب البيطري
السنة: 2010
الدرجة: دبلوم عالي
الجامعة: جامعة البصرة
اللغة: العربية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: تهدف هذه الدراسة الى معرفة الاسباب الرئيسية لعسر الولادة في الجاموس الذي يؤدي الى حدوث خسائر اقتصادية كبيرة نتيجة لموت المواليد، وزيادة فترة المخاض، زيادة تكاليف العلاجات البيطرية، انخفاض في الاداء التناسلي المستقبلي للاناث المجهضة، احيانا يؤدي الى فقدان | The aim of the present study was to find out the common major causative agents of dystocia. Dystocia causes important economic losses due to fetus death loss ,increased labor ,increased veterinary cost, reduced subsequent reproductive performance of the dam, potential loss of buffaloes, and reduced milk production. Many factors affecting calving difficulty, including birth weight of the fetus, pelvic area of the dam, gestation length,sex of the fetus, body condition of the female at calving, inadequate heifer development , abnormal presentation of the fetus and abnormal hormones levels in the female when giving birth.The major cause of dystocia is a disproportion between the birth weight and dam pelvic area. The study concluded that the selection of sires based on birth weight is a much more effective tool that selection of replacement heifers based on pelvic area to reduce dystocia in first pregnant heifers.The proper feeding and management is the right solution to decrease the incidence of dystocia.

Coccidiosis In Poultry

اسم المؤلف: يثرب خضر عبيس
اسم المشرف: نافع صبيح جاسم
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الامراض - الدواجن
الدرجة: دبلوم عالي
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: تعتبر الكوكسيديا في الدواجن واحدة من الامراض الرئيسية التي تؤثر على اداء الدواجن المرباة تحت نظام الانتاج المكثف الذي يؤثر على صناعة الدواجن في جميع انحاء العالم، بخسائر اقتصادية كبيرة عن طريق قلة التحويل الغذائي وخفض الانتاجية. هذا ليس فقط يعيق نمو الدجا | Coccidiosis in poultry is still considered as one of the main diseases affecting performance of poultry reared under intensive production system that affects the poultry industry worldwide , having major economic losses in poultry by reducing performance and decreasing productivity.this disease not only hinders the growth of chickens but also facilitates other epidemic diseases. Coccidiosis is mainly controld by prophylactic coccidioststs administrated in the feed. However , the extensive use of these drugs has resulted in the development of drug resistance by Eimeria spp., Which causes Coccidiosis.The aim of the study was to updated the recent information of of infection,gross evaluation of the intestinal tract and microscopic evaluation of wet smear are used as routine diagnostic methods and to acquire data on the prevalence of coccidiosis and drug resistance of field isolated in chickens,Frequent use of anticoccidial drugs ,however , has resulted in the development of resistance in the Eimerian spp. Because farmers mainly rely on the prophylactic and therapeutic use of chemicals for the control of avian coccidiosis. Increasing awareness about populic health hazards associated with drug residues in food chain has also added to the constraints in using synthetic drugs for treatment and control of disease in animals and control methods according to the collected formation chickens were in danger of clinical coccidiosis , and here coccidia generated a certine degree of resistance and not easy ty control in our industry in Iraq because of that the poultry industry in Iraq is not as integrated system without strict biosecurity. The study also highlight the information on the anticoccidial vaccines are in the market with controversial efficacy.

دراسة تاثير الفصول على بعض الصفات التشريحية والفسلجية للجهاز التناسلي في ذكور الجمال وحيدة السنام (Camelus Dromedarius) Study of The Seasonal Effect On The Some Anatomical And Physiological Features of Parts of The Genital System In Adult Male One Humped Camel (Camelus Dromedarius)

اسم المؤلف: عماد حمزة مروح
اسم المشرف: ضياء حسين جاسم الدليمي
الموضوع العام: الطب البيطري
السنة: 2013
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية على (96 عينة) لاجهزة تناسلية (خصى وبرابخ )ودم لذكور جمال ناضجة جنسيا بمعدل (6 - 5سنة) بعد التاكد من سلامتها قبل الذبح وبعده والتاكد من عمرها بواسطة المعادلة السنية من مجازر (النجف وعفك والديوانية ) لمدة سنة كاملة بواقع (8عينة) لكل شه | The current study was conducted on(96 samples) of genital organs (testes and epididymis) as well as blood of male mature camels (5 - 6 years) after the confirmation of their health before and after slaughter, and to make sure from their ages by the dential equation,these sample were collected from abbatoris of AL - Najaf, Afak and Diwaniya) for the full year with (8 samples) per - month for the purpose of determination parameters anatomical parameters for some of the genital system of the testes and epididymis (right and left), physiological parameter (hormonal elements chemical), the study anatomical results biggest weight, length, width and circumference of the lift testis and the weight and length of the left epididymis , mis recorded in winter significally(p <0.05), which reached(90.041 ± 0.613, 103.904 ± 0.633, 50.541 ± 1.957, 256.812 ± 0.615, 40.500 ± 0.288, 109±0.7), respectively, while less weight, length, width, circumference, weight and length of of the testis left and weight length of lift epididymis which recorded in the summer significally (p <0.05)and reached (85.666 ± 0.441, 92 ± 0.357,, 40.583 ± 0.220, 242.266 ± 0.15, 35.083 ± 0.083, 94.34 ± 0.45) respectively, while the measurements were in the weight, length, width and circumference of the right testis and weight and length of the right epididymis was recorded in winter and the level of significance (p <0.05), recorded(89.373 ± 0.474, 101.958 ± 0.622, 48.895 ± 1.181, 256.060 ± o.688, 35.945 ± 2.878,30.728 ± 0.518) respectively, , while the measurements of the less weight, length, width and circumference of the right testis and weight and length of the right epididymis was recorded in the summer in level of significance (p <0.05)and recorded (84.700±0.472,97.314±0.291,39.666±0.707,241.104±0.104,26.395±0.055, 92.5±0.3) respectively, the results of physiological and features related with hormonal the measurements that Folicul stimulate hormone (FSH) and lutyal hormone(LH) and (Testosterone hormone) have recorded the highest concentration in the winter and the level of significance( p<0.05) and recorded (5.128 ± 0.455, 2.770 ± 0.3184, 10 ± 1), respectively, while the lowest levels were recorded in summer with level of significance( p<0.05) and recorded(1.633 ±0.130 IU,2.145 ± 0.13 IU, 3.5 ± 0.091 ng/ml) while prolactin hormone has recorded lowest level of significance (p <0.05) in the winter and the highest level in the summer which recorded (102.2 ± 8.405 IU ,244 ± 24.463 IU)respect ally. the chemical elements increased their ranges in the winter and spring (p <0.05) which reached each of calcium, magnesium, sodium and potassium (8.791 ± 0.122 mg/dl, 3.016 ± 0.130 mg/dl, 147.916±2.061 Mmol/L, 7.000±0.003Mmol/L) and in the spring(8.100±0.52mg/dl,2.279±0.056mg/dl,146.458±3.129Mmol/L,8.405±5.181Mmol/L).while the lowest levels were in summer(p<0.05)which recorded(7.683 ±0.202, 2.236 ±0.148mg/dl,145.454 ±0.275Mmol/L,24.463 ± 5.027Mmol/L) respectively

دراسة تاثير برامج الرعاية التناسلية على الخصوبة خلال فترة النفاس في ابقار الحليب Study of The Effect of Reproductive Care Programs On Fertility During Postpartum Period

اسم المؤلف: اسراء راضي لطيف الزبيدي
اسم المشرف: عبد الكريم محمد جعفر
الموضوع العام: الطب البيطري
السنة: 2013
الدرجة: دبلوم عالي
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: تهدف الدراسة الى استعراض المراجع المهمة التي تهتم بالرعاية التناسلية لحيوانات المزرعة وخاصة الابقار لما لها من اهمية كبيرة في حيات الانسان حيث شملت استعراض لبرامج الرعاية التناسلية والطرق اللازمة للحفاظ على اعلى انتاج حيواني وكما شملت الدراسة اهم الامراض | This study aimed to review important references which deal with reproductive care of farm animals specially cows because of the great importance in human life. That included the ways to maintain high animal production and it included the most important maternal disease that cause reduction in animal reproductive efficient and perdition or exclusion of animal.The study review predisposing factors and environmental conditions which cause significant economic losses perhaps the nutrition has been consider the most importance factor. And this study also covered the roles of hormones because of the active effect in reproductive efficient and explain each hormone and its affect on the animal body during pregnancy and correlation with other hormones.The reproductive care programs are the most programs which must applied for high animal production and reduce the reproductive disease and treat them with simple ways to decrease economic losses that affect on owner s yield material then affect on national economy directly so shall be taken into consideration. The most importance problems and correlation with good management for high reproductive efficient of farm animals specially dairy cattle. Supervisor's certificate We certify that this study (the study of the effect of reproductive care programs on fertility during postpartum period in dairy cattle) was prepared under our supervision at the college of Veterinary Medicine of AL - Qadissiyah University, as a partial fulfillment of the requirement of the degree of Higher Diploma of Science in Veterinary Medicine

عزل وتشخيص جزيئي لمورثات مجاميع الانماط المصلية لجرثومة اللستيريا المستوحدة Listeria monocytogenes من الانسان والحيوانات في محافظة القادسية Isolation And Molecular Detection of Serotype Genes Group of Listeria Monocytogenes From Human And Animals In Al - Qadissyia Province

اسم المؤلف: حسين عمران كريم العابدي
اسم المشرف: هدى عبد الهادي علي النصراوي
الموضوع العام: الطب البيطري
السنة: 2015
الموضوع الدقيق: الامراض المشتركة
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية خلال الفترة من تشرين الثاني 2014 الى نيسان 2015، جمعت العينات المرضية من النساء التي تعاني من حالات الاجهاض وولادة مبكرة والاطفال المصابين بالتهاب السحايا من مستشفى الولادة والاطفال التعليمي وقد جمعت العينات تحت اشراف طبي متخصص وكان | This study was carried out during the period from November 2014 to April 2015, whereas samples were collected from women that suffered of abortion and infected children in the maternal and children hospital in Al - Qadissiya province , so the samples were collected under supervising of a specialist medicine , the number of taken samples of the women is 65 samples , while the number of taken samples of children is 32 samples , so the samples that belong to animals have included a gall bladder samples were collected from Al - Diwaniya slaughterhouse were 100 samples of sheep and 100 samples of cows. in addition to collect 200 samples of milk as 100 samples for each sheep and cows from different rural zones in al - Qadissiya province. L.monocytogenes was isolated by using oxford listeria selective agar for listeria , so the special stimulator for growth of the bacteria was added to it in order to determine the type of bacteria , also it diagnosed an isolates for L.monocytogenes by using the microscopically examination and biochemical tests , furthermore the germ isolates was planted on blood agar for diagnosing the blood analysis type : ? - heamolysis as affirmative checking for the isolates. also PCR technique used for affirming the diagnosing of L. monocytogenes by using the initiator for the blood analysis gene (hly) , whereas all the L. monocytogenes isolates' gave a positive result in inspection , so this technique is used too in the detection about the serous types for L.monocytogenes isolates by the molecular diagnosing for the fierce genes of the germ and these are (D1,D2,Glt,FlaA and MAMA gene ). The results of the research showed that isolating and diagnosing percentage of the Listeria monocytogenes is about 9.27%, whereas the isolation percentage in women infected in abortion is 4.61%, while the percentage of listeria germ isolation was higher in the children that infected in meningitis whereas it was 18.75% of the total amount of the samples.As for the percentage of the isolating in sheep it was 4% and 7% for milk and gall bladder respectively. In the cows the isolation percentage of the germ from milk and gall bladder was 2% and 3% respectively. So the the results of isolating for listeria germ during the study period in human and animals were disparate , whereas the highest percentage of isolation for the germ in human were scored in January and February months of the year whereas it scored 20% and 16% respectively.As for sheep the percentage of isolation was higher in December and January months whereas it is 6.25% and 10% respectively , while in the cows the percentage was higher in January and February months where it is 4.2% and 7.4% respectively. Regarding The results of detection about the genes of the serous types for the isolates of L.monocytogenes by using PCR technique 14 isolates of the samples showed a positive result when they react with the initiator for gene (D1)in percentage about 56%, so this isolates showed a positive result when they react with the initiator for gene (Glt) as amount of 5 isolates and they classified to be belong to the serous types (1/2B or 3B), while 9 isolates gave a negative result in the inspection , whereas these isolates were tested with the initiator for gene (MAMA), 5 isolates showed a positive result in this reaction with this gene and they classified to be belong to the serous types (4c or 4a), while 4 isolates gave a negative result as they classified to be belong to the serous types (4b or 4d or 4c).As for the isolates' that gave a negative result with the initiator of gene (D1)there are 11 isolates all these isolates gave a positive result when they inspected with the initiator of gene (D2) in a percentage about 44%, so when these isolates inspected with the initiator for gene (FLaA) then 6 isolates of them gave a positive result in the inspection and classified as they belong to (1/2a or 3a), while 5 isolates of them gave a negative result in the inspection and classified as they belong to (1/2c or 3c). As for the serous types that have not diagnosed in the germ isolates of the human there are(1/2a or 3c), while in the germ isolates of the sheep the serous types (4a or 4c) have not been diagnosed , then the serous types (1/2b or 3b) have not been scored in the cows. The present study concluded that the percentage of infection in L.monocytogenes was high in human in al - Qadissiya province , in which that refer to the risks of the diseases and health problems spread that could be caused by L.monocytogenes , also the results included isolating the germ from milk and gall bladder samples for sheep and cows that could be a source to carry the infection to the human by contaminating the meat, milk and its derivatives'. whereas the isolation percentage of the germ was higher in the cold months of the year in human and animals, so the highest isolation percentage of the serous types for the L.monocytogenes in human and cows were (4a , 4c) , while in sheep the serous types were (1/3c,3c).

الامراضية السمية لنابروكسين الصوديوم في الجرذان البيضاء مع الكيتوبروفين كعامل تحكم ايجابي Toxicological Pathology of Naproxen Sodium In White Laboratory Sprague Dawley Rats (Rattus Rattus) With Ketoprofen As Positive Control

اسم المؤلف: ثائر علي محسن
اسم المشرف: زينب وحيد خضير صالح كاظم مجيد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الطب البيطري
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: ان الغرض من الدراسة هو تحديد السمية المرضية الدوائية لنابروكسين الصوديوم (كعامل مضاد التهاب غير استيرويدي) في الجرذان البيضاء، مع الكيتوبروفين كعامل تحكم ايجابي. لانها ذات فائدة على نطاق واسع في الحيوان والانسان، لتلقي العلاج الميداني، ومعرفة العلامات الس | The purposes of study are : first, to determine the toxicity and pathogenesis of naproxen sodium [as non - steroidal anti - inflammatory agent(NSAIDs)] in white rats in comparison with ketoprofen as positive control, as they are of wide use in animal and human, for treatment of variable disease; and knowledge of the clinical signs, macroscopic changes and microscopic changes by toxic dose of naproxen, second to observe note - 1 the histological changes in comparison with the control group (as untreated group), and note - 2 to examine the biochemical parameters in response to naproxen treatment, note - 3 where naproxen is (NSAID) with analgesic and antipyretic properties. In the present study, white rats are used. Divided into five groups each group contain 12 rats; these group divided into the following manner : The first group - C, representing untreated group has been treated with normal saline only; the second group - L, representing the low dose which has received (5mg/kg B.W) of naproxen sodium, while the third group - I is the intermediate dose, which has received (10mg/kg B.W); the fourth group - H, representing the high dose, that has received (20mg/kg B.W), and finally the fifth group, representing the positive control group, has received(4mg/kg B.W of ketoprofen). The method of dosing these animals are by oral gavage which continues for three months. All the animal groups have been put in the same conditions of temperature and humidity. This study shows that the treatment with naproxen sodium has led to significant gradually increase in the body weight of both high dose and intermediate dose groups in early treatment period in comparison with the control group. In contrast, the animals which have received low dose of naproxen sodium show only minimal and gradual increase in their body weight in comparison with the intermediate and high dose. As well as there has been noticeable little increase and decrease in some value of liver and kidney enzymes concentrations(AST, ALT, ALK, Urea/Cr as treated with naproxen and positive control of ketoprofen). The study also showed that the treatment with naproxen sodium had led to clinical findings include uterine hemorrhage and still birth which specially occurs in the last period of pregnancy. Infections happen in some regions of body forming abscess in the subcutaneous tissue of neck, leg, cheek. The macroscopic findings include pallor of liver and Abscess of the liver and kidney, also there is increase in size of the spleen as a result of congestion of the splenic red pulp and minimal changes of the mucosa of the stomach. Moreover the microscopic findings include minimal hepatic periportal fibrosis , moderate diffuse vacuolation of hepatocytes, area of vacuolated degenerative centrilobular hepatocyte arround the central vein and subcapsular infiltration of inflammatory cells. There was necrosis of renal cortical tubules and atrophy of glommeruli, vacuolation of mesenchymal glomerulular cells , dilated vacuolated cortical tubules, some with degeneration and loss of epithelial in lumen and degenerative necrotic tubules. In addition there is degenerative and vacuolative changes of myocardial muscle cells, and atrophy of myocardial muscle cells; and there was an evidence of interstitial edema. as well as there is atrophy of white pulp lymphoid tissue and congested of red pulp, also there was increase cellularity of red pulp(present of macrophage cells in red pulp). Furthermore,the present study exposes that the treatment with naproxen sodium would lead to other histo - pathological changes in the stomach and small intestine include vacuolation of mucosal epithelial cells of the stomach and inflammatory cells in the serosa with noticeable presence of prominant ganglion cells in the outer zone of muscularis externa and degeneration of mucosal lining and mucosal glands in the lamina propria of stomach(glandular region). In addition there have been vacuolation and degeneration of mucosal epithelial lining of small intestine , ulceration of the mucosa in the small intestine , increase in length of the villi and infiltration of inflammatory cells in lamina properia and inflammatory cells in the serosa and vacuolation of muscularis externa. In the colon there is vacuolation (prominent mucous gland) and mix of inflammatory cells infiltration, vacuolation (increase mucous gland) and a few mononuclear cells in the lamina propria and there was increase minimal fibrosis.Either in the uterus there was thicken fibrotic lamina propria and few endometrial gland. Finally the pathological changes that have been found for high dose group of naproxen prove to be more severe than both the intermediate and low dose groups.

دراسة تاثير الخصي في مستويات بعض الهرمونات التناسلية وبعض المعايير الدمية في ذكور الماعز المحلي الاسود Study The Effect of Castration On The Levels of Some Reproductive Hormones , And Some Hematological Parameters In The Local Black Buck

اسم المؤلف: باسم حميد عبد علي
اسم المشرف: ضياء حسين جاسم الدليمي
الموضوع العام: الطب البيطري
السنة: 2011
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت الدراسة لغرض التعرف على تاثير عملية الخصي في ذكور الماعز المحلي الاسود في مستويات الهرمونات التناسلية والصورة الدمية , وقد اشتملت الدراسة على (25) ذكرا تراوحت اعمارها بين (1.5 - 2.5) سنة وكانت خالية من الامراض والمشاكل التناسلية , وقسمت عشوائيا ال | The current study was conducted for the purpose of identification the effect of the castration in male goats on levels of reproductive hormones and some hematological parameters , and had included (25) males ranged from ages between (1.5 - 2.5) years old and was free from diseases and reproductive problems. The animals in this study were randomly divided into two groups (control group includes (10) male and experimental group includes (15) male) that housed in same conditions of nutrition and management. The levels of reproductive hormones include (Spermatogenesis Stimulating hormone (SSH) , Interstitial cell stimulating hormone (ICSH), testosterone, Estradiol - 17 beta and progesterone) as well as blood parameters that include (red blood cells( RBCs), total white blood cells ( tWBCs), packed cell volume (PCV), hemoglobin concentration (Hb), total protein and cholesterol concentration) were estimated three times before castration and in intervals of two weeks between examination and other , Experimental animals were examined after castration all hormones and blood parameters checked two weeks after castration, then after four weeks from castration, and re - measured all hormones and blood parameters after six weeks of the castration. The method of analysis Radioimmunoassay (RIA) was used to measure the levels of reproductive hormones in animals blood serums also the routine blood tests were use for checking the blood parameters. The results revealed that there are significant increased in the level of ICSH in experimental animals after castration (0.345 ± 0.0413) mIU / ml while the level of testosterone and estradiol - 17 beta significantly decrease in experimental animals after castration and the results were (0.0225 ± 0.0036) ng/ ml and (0.93 ± 0.15) pg/ ml, respectively. While castration did not show any significant effect on the levels of reproductive hormones SSH and progesterone (0.145 ± 0.01) mIU/ ml and (0.295 ± 0.03) ng /ml respectively in experimental group. The result showed that there were significant increased in RBCs , PCV, total protein and cholesterol (17125 ± 335.18) × 10 3 cell/µL , (37.7 ± 0.40) , (6.84 ± 0.25) g /100 ml and (84.41 ± 6.6) mg/100 ml respectively in experimental group after castration, while tWBCs and hemoglobin didn't affect after castration in experimental group (10788 ± 429.39) cell /µL and (11.35 ± 0.180) g/ 100 ml, respectively.

تشخيص فايروس التهاب القصبات المعدي في حقول دجاج اللحم في محافظة ذي قار باستخدام تقنية الاليزا (ELISA) وتفاعل سلسلة البلمرة المنعكس في الوقت الحقيقي (rRT - PCR) Identification of Infectious Bronchitis Virus In Thi - Qar Province In Broilers Farms By Using ELISA and rRT - PCR

اسم المؤلف: ظافر ياسر عزيز الفاضلي
اسم المشرف: نافع صبيح جاسم
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الامراض - الدواجن
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت هذه الدراسة لتقييم مدى انتشار مرض التهاب القصبات المعدي الفيروسي في دجاج اللحم في محافظة ذي قار, قسمت منطقة الدراسة جغرافيا الى خمسة مناطق (شمالية, جنوبية, غربية , شرقية, مركزية) حيث تمت الدراسة على عشرون حقل دجاج لحم غير ملقحة اربعة قاعات من كل منط | The current study was conducted for evaluation of prevalence of IB in broilers in the Thi - Qar province, which geographically divided into five regions, (Northern, Southern, Western, Eastern and central area), twenty broiler farms without history of previous vaccination, four from each region were included in this study. Serum and autopsies were collected from affected birds after recording of the clinical signs that observed on the birds; positive serum samples that detected by rapid test were used for evaluation the antibodies titrations by ELISA technique, while the histological specimens (trachea, lung and kidney) were used for detection of histopathological changes and detection of presence of the IBV infection by molecular approach (real time - PCR). The clinical manifestation includes : typical respiratory sings of IB infections, with depression, rough feather, and assembling near the heat source, as well as some birds were found dead with mortality rate ranging between 30 - 80%. Also 96 serum samples were collected from other broiler farms as following ( 42 asymptomatic vaccinated, 54 asymptomatic non - vaccinated, 26 symptomatic vaccinated) for ELISA and real time PCR tests. The result of rapid test showed that the percentages were different among the areas of study when the southern area revealed the highest percentage (80%) among the others followed by the northern area and western (70%), then central and eastern(65%). The results of ELISA showed a high titer for antibody of IBV in all these farms in areas of the study, but the highly significant results (P<0.05) were found in the southern area(7032.2±1640.92) and then northern area (5722.18±2060.1), a less significant differences were in central and eastern areas (3188.11±742.45; 3161.8±52.6) respectively. In relation to age, the high titer of IB antibodies in total 20 farm by ELISA were recorded in 12 farms at 4 weeks of age (60%) followed by 4 farms at 5 weeks of age (20%), 3 farms at 3 weeks of age (15%) and 1 farm at 2 weeks of age (5%), while there is no recorded infection in farms at 6 ages. According to history of vaccination and clinical manifestation of tested birds, most of the tested flocks showed high level of antibody titers to IBV by ELISA technique in asymptomatic vaccinated chickens samples 38/42 (90%) followed by asymptomatic non vaccinated chickens 8 (14.8%) and symptomatic vaccinated chickens 6(23.07%). While rRT - PCR showed that 69 ( 80%) sample were revealed positive results. The most important gross lesion observed on immediately the necropsy after death were tracheal congestion, caseous exudates in the trachea, pneumonia, airsacculitis, pericarditis and perihepatitis, as well as, nephritis; while The histopathological changes were summarized by desquamation of tracheal epithelial cells and hemorrhage with infiltration of inflammatory cells specially lymphocyte cells, hyperplasia of epithelial cells with hemorrhage, lung sections showed severe infiltration of inflammatory cells mostly lymphocyte cells and severe congestion with spots of pneumonia and the histopathological changes in kidneys were characterized by tubules degeneration , glomerular distention with severe hemorrhage and lymphocyte infiltration.

الامراضية السمية لكبريتات الثاليوم في الجرذان المختبرية البيضاءSprague Dawley (Rattus norvegicus) Toxicological Pathology of Thallium Sulfate In White Laboratory Spraguedawley Rats (Rattus Norvegicus)

اسم المؤلف: مازن عادل جايان
اسم المشرف: زينب وحيد خضير صالح كاظم مجيد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الطب البيطري
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية في البيت الحيواني التابع لكلية الطب البيطري - جامعة البصرة لمعرفة الامراضية السمية لكبريتات الثاليوم على انسجة الجسم المختلفة وبعض المعايير الكيموحيوية للجرذان المختبرية البيضاء Sprague Dawley (Rattus norvegicus). في هذه الدراسة تم | The present study was conducted at the College of Veterinary Medicine - University of Basrah to investigate the effect of Thallium Sulfate on some physiological parameters and histological changes in the Laboratory White Sprague Dawley Rats (Rattus norvegicus). In this study 48 rats were used, that were sexually mature (16 weeks age and 250±50 gm weighing). These animals were divided into four groups each group contain 12 rats. All of these groups administrated orally with : - normal saline ,0.4 ,0.8 ,1.6 mg /kg b. w. of thallium sulfate respectively for 90 days.After ending of this period, all animals were sacrificed after anesthesia by chloroform inhalation for the study. The study includes the effects of thallium sulfate on some biochemical parameters as estimation of serum liver function enzymes ( AST and ALT ) and kidney function enzymes ( Urea and Creatinine ). This study also includes the estimation of serum acetylcholine (Ach) concentration. The present study revealed histopathological effects of thallium sulfate on nervous system, liver, kidneys, eyes, skin, and testis. In addition to its electron microscopic changes were occurred on mitochondria of hepatocyes and cells of proximal convoluted tubules of kidney. The results of this study showed significant increase (P? 0.05) in liver enzymes and kidney function enzymes and acetylcholine concentration in treated groups in comparison with control group. There is also histopathological changes occurred in nervous tissue (brain, spinal cord, and sciatic nerve), liver, kidney, testis, eye, and skin. The ultrastructural changes showed swelling of mitochondria and also an increased in number in rats treated with 1.6 mg/kg b.w. of thallium sulfate in comparison with control group.

تركيز المعادن الثقيلة في حليب الابقار والاغنام والماعز في محافظـة القادسية The Concentration of Heavy Metals In Milk of Cows , Sheep & Goats In Al - Qadisiya Province

اسم المؤلف: علياء حسن علـي السماوي
اسم المشرف: كريم ناصر طاهر
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الصحة العامة
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت هذه الدراسة في محافظة القادسية للمدة من كانون الاول 2012 لغاية اذار 2013 شملت خمسة مناطق مختلفة من محافظة القادسية هي كل من (مركز الديوانية وناحية السنية وناحية الشافعية وناحية الدغارة وقضاء الحمزة) لغرض تحديد مدى تلوث الحليب الخام ببعض المعادن | This study was carried out in AL - Qadissiyah province during the period from December 2012 to March 2013 involved five different regions such as (Diwaniyah city center , Saniyah district , shafeia district , Dagharah district and AL - Hamza district) to determine the level of contamination of raw milk with the toxic heavy metals such as Cadmium (Cd), Lead (Pb), Nikel (Ni), Arsenic (As) and Mercury (Hg). A total of 150 raw milk samples were collected from 150 animals belonged to three species involved (50) cows , (50) sheep and (50) goats selected randomly, ten animals per each species per regions. The results of a statistical analysis of the experimental data showed that : Chemical components of milk 1.There are a significant differences (p <0.05) in all contents of milk among different species of studied animals (cows , sheep and goats). Except fat content for cows and goats milk were not significant different. Sheep's milk had significantly (p<0.05) of (protein, fat, solids not - fat and ash) in comparison to cow's and goat's milk (7.535, 6.617, 12.026 and 0.646) % respectively. Cow's milk had significantly (p<0.05) higher lactose content (4.757%) than both sheep's and goat's milk. components of milk 2. PhysicalThe results revealed that there were significant differences (p <0.05) in all physical characteristics of milk among different species of animals involved in this study (cows, sheep and goats). Sheep milk had significantly (p<0.05) (Titratable Acidity 0.182% and conductivity 3.214 mS/cm) than both cow's and goat's milk , goat's milk contains the highest specific gravity 1.057mg /100 ml while the pH values of cow's , sheep's and goat's milk were similar. Heavy metals in milk - Effect of Species The results revealed that significant differences (P<0.05) among the mean values of heavy metal concentrations included in the study (Cadmium (Cd) , lead (Pb), Nikel (Ni), Arsenic (As) and Mercury (Hg) in milk of different species (cows , sheep and goats). Sheep's milk had significantly levels of such heavy metals (0.251, 0.801, 0.563, 0.283 and 0.124) mg/ l respectively than both cow's and goat's milk while cow's milk had significantly the lower levels (0.098, 0.311, 0.221, and 0.122 , 0.037) mg / l respectively. - Effect of regions : The results showed that significant differences (P<0.05) in the means values of heavy metal concentrations in milk among different regions. The Highest levels of heavy metals were observed in AL - Hamza district (0.184, 0.624, 0.494, 0.246 and 0.119) mg / l respectively and the lowest levels of heavy metals were noticed in Dagharah (0.144 , 0.507, 0.382 , 0.167 and 0.061) mg / l respectively. - Effect of month : The results of the statistical analysis showed that there were non - significant differences in the average concentrations of cadmium, lead and arsenic among months while a significant differences (P <0.05) were observed in the level of nikel between march and other studied months [(0.494) mg / l in march and (0.397, 0.418 and 0.415) mg / l for December, January and February respectively]. Also the results showed that there were a significant differences (P<0.05) in the levels of mercury between march and each of January and February [(0.106) mg / l in march and (0.081 and 0.083) mg / l in January and February respectively]. From the results obtained in the present study,it can be concluded that : 1 - Heavy metals like cadmium (Cd), lead (Pb), Nikel (Ni), Arsenic (As and Mercury (Hg) which distributed among different sites were exceed the maximum acceptable limits set by WHO and EPA. 2 - High concentration of heavy metals (Cd, Pb, Ni, As and Hg) in city center site may be due to the industrial activities. 3 - High concentration of heavy metals in the other sites may be due to application of waste water for agriculture purposes (irrigation) which pollute the soil and also be allowing toxic metals to enter in to the food chain posing a serious health hazard.

التحري عن اهم الامراض الفيروسية التنفسية في دجاج اللحم باستخدام فحص الاليزا (ELISA) وتقنية تفاعل سلسلة البلمرة المنعكس في الوقت الحقيقي (rRT - PCR) في محافظة الديوانية Detection of Certain Viral Respiratory Diseases In Broiler Chickens By ELISA And Real Time RT - PCR Technique In Al - Diwaniyia Province

اسم المؤلف: عباس هادي جاسم المحمودي
اسم المشرف: نافع صبيح جاسم
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الامراض - الدواجن
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: تعد انفلونزا الطيور والتهاب القصبات المعدي والنيوكاسل من الامراض المهمة اقتصاديا في صناعة الدواجن.صممت الدراسة الحالية لتسليط الضوء على دور فيروسات ND, IB, AI , ومعرفة مدى انتشارها في احداث الاوبئة التنفسية في دجاج اللحم باستخدام تقنية الاستنساخ المن | Avian influenza, Newcastle disease and Infectious bronchitis are diseases that have economical importance in poultry industry. This study was designed to clarify the roles of IBV, AIV and NDV in an outbreaks of respiratory diseases in broiler chickens by using ELISA and real time RT - PCR assay in Al - Diwaniyia province , Iraq. A total of 30 commercial broiler flocks with high mortality (20 to 80 %) in Al - Diwaniyia province were investigated.Tracheal swabs and tissue specimens ( Trachea, lung, kidney and cecal tonsils ) were tested initially by rapid test for detection of Infectious bronchitis virus ( IBV ) , Influenza type A virus ( AIV) and Newcastle disease virus (NDV).The total results of rapid immunochromatography assay showed that out of 30 flocks 28 ( 93.33%) were positive for IBV and 21(70%) flocks were positive for AIV while 4(13.33%) flocks were positive for NDV. Blood samples were collected for detection of antibodies against IBV, AIV & NDV in serum samples , the results of indirect ELISA showed that out of 30 flocks were 30(100%) gave positive result with indirect ELISA test for IBV and 23(76.67%) flocks were positive for AIV (H9 ) whereas 5(16.67%) flocks showed positive result for NDV. The result of rRT - PCR showed out of 30 (100%) flocks were positive for IBV and 23(76.67%) positive for AIV (H9) whereas 5(16.67%) flocks were gave positive results for NDV. In conclusion the high positivity in the examined broiler flocks were mainly due to mixed infections of IBV, AIV(H9) and NDV, However we concluded that IBV and AIV were most important causes of respiratory diseases in this study. Also this study demonstrated that Real time qRT - PCR technique and ELISA were rapid and accurate as diagnostic tool in early detection of IBV, AIV and NDV.

التاثيرات السمية المرضية للسايبرمثرين على بعض المعايير الكيموحيوية, وفعالية الاستايل كولين في الجرذان البالغة Toxicopathological Effects of Cypermethrine On Some Biochemical Parameters And Acetylecholine Activity In Sprague Dawley Rarts (Ruttus Norvegicus)

اسم المؤلف: طلال جبل حسين
اسم المشرف: زينب وحيد خضير صالح كاظم مجيد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الطب البيطري
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية في البيت الحيواني التابع لكلية الطب البيطري في جامعة البصرة لتقييم التاثير السمي للجرع المختلفه للسايبرمثرين على الدماغ والحبل الشوكي والعصب الوركي والكبد والكلية والخصية اضافة الى تاثيره على انزيمات الكبد(AST,ALT) وانزيمات الكلية (ا | The present study was conducted in the laboratory animal house - college of veterinary medicine - University of Basra to investigate the Toxicological effects of different doses of Cypermthrin on Brain, Spinal cord ,Sciatic nerve, Liver, Kidney ,and Testis and also its effect on liver enzymes (ALT and AST), kidney enzymes (urea and creatinine) ,and serum acetylcholine (Ach) in adult Sprague dawley rats (Rattus norvegicus). Fourty eight adult rats were used , they were divided randomly and equally into four groups. Control group orally dosed with normal saline for 90 days. The other three groups were dosed orally with different three doses of cypermthrin , high dose ( 64 mg / kg b.w. ) intermediate dose ( 32 mg / kg b.w. ) and low dose ( 16mg / kg b.w. ). The results showed that there were hitopathological changes of brain, spinal cord and Sciatic nerve that revealed there were a dose dependent increase in vaccuolation in nerves fibers to be affect larg number of nerve fiber in high dose and also affected few numbers of nerve fibers in low dose. Also there were changes in liver ,kidney and testis. Serum AST, ALT, urea, creatinine and acetylecholine concentrations increased significantly ( p ? 0.05) in rats exposed to cypermethrin in comparisons with control. In conclusion cypermthrin affects positivly on histopathological findings of nervous system, liver tissues and enzymes, kidney tissues and enzymes ,and Acetylcholine (Ach) neurotransmitter.

دراسة شكلية ونسجية وكيمياء نسجية للمعدة في الجاموس المحلي البالغ Bubalus bubalis Histomorphological And Histochemical Study of Stomach of The Adult Local Buffalo Bubalus Bubali

اسم المؤلف: سوسن غفوري احمد
اسم المشرف: فوزي صدام محسن الاسدي
الموضوع العام: الطب البيطري
السنة: 2015
الموضوع الدقيق: التشريح والانسجة والاجنة
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: العربية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: اجريت هذه الدراسة على عشرين معدة للجاموس المحلي الخالية من الامراض والتي جمعتمن مجزرة العـــشار في البصرة. تضمنت الدراسة الشكلية قياسات متعددة للاجزاء الاربعة من المعدة كالطول والارتفاع علاوة على حساب معدل عدد الحليمات الموجودة في الكرش في السنتمتر ال | 20 Stomach of healthy stomach of local buffalo were used in present study which collected from Al. Ashar Massacre in the city of Basrah.morphological study included several measurements for all parts of Stomach like length and width in addition to calculate the average of number of papillae that present in rumen per each Square centimeter and the average of length of these papillae as well as find the diameters of openings between chambers of Stomach. While the histological part was comprise investigate the histological structure of the wall of chambers of Stomach. Histological Section were prepared from these chambers stained with hematoxylin and eosin Stain to Study the general characters of tissue, while other sections were Stain with special Stains to detect the histochemical properties of these tissues. The morphological study showed that the stomach of buffalo formed from four chambers these are rumen, reticulum , omasum and abomasum differs in their length and width. The inner lining of rumen was contained on many papillae the average of length was 800 micrometers while their average of number was 118 papilla /cm2. while the inner lining of reticulam was included several number of lamellae which arranged in form like honeycomb. Omasal lining showed crescent lamella differs in their number and length while the wall of abomasums is divided in to two regions real gastro glands origin region and the color red and has a helical folds the seconed region is the pyloric glands region, a light colored region and the container on the irregular folds. In Histological part the present study revealed that the wall of all the chamber in buffalos, stomach were histologically composed from four layers; these are tunica Mucosa , Submucosa , Muscularis and Serosa.The tunica Mucosa of rumen was characterized by of papillae that differs in their number and length according to its region in rumen while the glands were abscent in lamina properia as well as abscent of muscularis mucosa, while the wall of abomasums appeared divided histologically into 3 regions ; cardiac , Fundic and pyloric region About the histochemical part , this study demonstrated that the collagen fibers were prevalent more density in Submucosal tunica than other histological tunicas in wall of rumen ,in contrast the elastic fibers were highly constricted in muscular tunica of the rumen and mucosal larger of reticulum in comparion with other tunicas and Submucosa of the Ommasum ,the elastic fibers showed prevalenced in all layers of the cardic region of the abomasums. this study showed prevalence of keratin in the mucosa denser than other layers in the rumen , reticulum and omasum while abscent in abomasum. this study also showed prevalence of glycogen and proteins in all parts of rumen as well as prevalence of fat and alkaline phosphatase activity in the wall of all chambers of stomach.

دراسة تشخيصية وامراضية نسجية للقناة الهضمية في الدجاج المنزلي Gallus gallus domasticus المصابة بالطفيليات المعوية في مدينة البصرة Diagnostic And Histopathological Study of Intestinal Tract of Domestic Fowl Gallus Gallus Domesticus Infected With Intestinal Parasites At Basrah City

اسم المؤلف: اسراء صبيح بداي الغنامي
اسم المشرف: غازي يعقوب عزال الامارة
الموضوع العام: الطب البيطري
السنة: 2013
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: امتدت الدراسة الحالية من شهر تشرين الاول 2011 ولغاية شهر اذار 2012 , حيث جمعت خلالها 108 نموذجا بواقع 36 عينة من الذكور و72 عينة من الاناث من الدجاج المحلي1758) Gallus gallus domesticus (Linnaeus, من محافظة البصرة بهدف عزل الديدان المتطفلة على القناة الهض | The recent study extended from October 2011 to January 2012, collected 108 samples by 36 samples of males and 72 samples of female of local chickens Gallus gallus domesticus (Linnaeus, 1758)from Basrah to isolate parasitic worms on the gastrointestinal tract and diagnosed as well as study percentage and severity of the infection, as well as monitoring biological activities of isolated parasites and find out macroscopic and pathological changes caused by these worms and find out the impact of tapeworms on the values of the blood parameters of chicken. The results showed infected of chicken with five types of tapeworms (Hymenolepis carioca, Raillietina tetragon, Raillietina cesticillus, Choanotania infundibulum, Cotugina sp) with percent of infection and severity reached 4.62%, 11.4; 19.44%, 12.09; 5.55%, 12.66; 9.25%, 12.6; 6.48 %, 11.14 respectively and got one type of nematodes Subulura brumpti with percentage of infection and severity reached 10.18%, 91 and three types of trematode Echinostoma revulatum, Hypoderm coniodium, Psilolecithum longorchum with percent of infection and severity reached 1.85%, 15.5; 0.92%, 10; 0.92% , 7 respectively.The results of the recent study showed that infection with two types is the most common reaching incidence of 25.92%, and study results indicated that there were significant differences between males and females in susceptibility to intestinal worms.Observed by studying the sites of worms in the gut that the proportion of tapeworms in the small intestine are more than in the large intestine while recorded nematodes only in the large intestine As for worms Trematode has found in the small intestine. The results also included monitoring biological activities of isolated parasites from the gastrointestinal tract from the beginning of the division of the egg and develop into a larva has been observed that the nematodes have the ability to survive outside the host, who were present more than tapeworms.the study contained a physiologic side on the impact of tapeworms on some blood parameters where showed infection of domestic fowl with anemia by observing the decrease in the number of red blood cells R.BC , hemoglobin Hb and P. CV while there was an increase in the number of white blood cells WBC. The study recorded the number of grossly and histological lesions in the intestine and the cecum of domestic chicken Because they infected with tapeworms, nematodes and flukes. grossly lesions included blockage and swelling in the intestines infected with tapeworm and cecum infected with nematode and appearance of rough nodules on the walls of the intestine infected with tapeworm with hemorrhage and the appearance of yellowish green purulent material in the inner wall of the intestines, and the histological changes has included atrophy of intestinal villi with sloughing and desquamation of epithelial layer with appearance of inflammation in the form of pseudomembrane and infiltration of inflammatory cells and coaglative necrosis, it have seen hemorrhage and superficial erosion in the mucous layer and sloughing of villi and epithelial layer with hyperplasia appearance purulent cells and destruction of intestinal glands and ulceration in the mucous layer in addition to the congestion

استخــدام فحصي الاليـزا واثباط التلازن الدموي في تحديد معيار الاضداد في افراخ اللحم المحصنة بطرق مختلفة ضد مرض النيوكاسل Using of Hi And Elisa For Detection of Antibody Titers Against Newcastle Disease Vaccines Using Different Methods of Vaccination In Broiler Chicks

اسم المؤلف: محمد حميد خلف
اسم المشرف: علي عبد سهم المياح
الموضوع العام: الطب البيطري
السنة: 2010
الموضوع الدقيق: الامراض - الدواجن
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: العربية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: استخدم في الدراسة 200 فرخ لحم سلالة روز بعمر يوم واحد وغير مجنس لغرض استخدام فحصي الاليزا واثباط التلازن الدموي في تحديد معيار الاضداد في افراخ اللحم المحصنة بطرق مختلفة ضد مرض النيوكاسل واجريت الدراسة في فرع الامراض وامراض الدواجن / كلية الطب البيطري / | In this study 200 Ross breed broiler chicks aged 1 day and in both sex used for using of ELISA and HI tests in determination the titer of antibody in broiler chicks which vaccinated by different ways against Newcastle disease. the study done in a special house in college of Veterinary Medicine / Basra University / Department of Pathology and Poultry disease. The chicks divided randomly to 5 treated groups each one contain 35 chicks and the 6th group not treated (Act as control) contain 25 chicks. All chicks provide free feed and the 5 groups vaccinated by different ways against Newcastle disease , in 7th day vaccinated with Hitchner B1 vaccine and in days ( 21 and 35) with LaSota vaccine.The 1st and 2nd groups vaccinated by drinking water , in the 1st group used of tap water mixed with Skimmed milk while in the 2nd group used of RO Water. The third group vaccinated by spray , the 4th group vaccinated with eyes drop and the 5th group vaccinated in nostril. The distilled water used with vaccine of third , 4th and 5th groups , the control group leaved without vaccination. All groups vaccinated against Gumboro disease in 14th day of age. The blood sample collected in ages of ( 1 , 21 , 35 , 49 ) days with the range of 10 specimens from each group and 5 specimens from the control group then serum separated in order to testing immunity by using of Elisa and HI tests.Because of maternal immunity the titer of antibody in the 1st day was very high in range different in probability (0.05 >P) in comparison with other days (21 , 35 , 49 ) in other groups.The result of ELISA test show that the 1st group was excellence in (49) days of age that used the tap water mixed with skimmed milk in comparison with other groups in days ( 21, 35 ) with range different in probability of (0.05 >P). The 2nd group which was used of RO water the second order while the third group which used the spray vaccination was in third order and the 4th and 5th groups were some that the same in result and there was no any moral different.The result of HI test show that the 1st group that used of tap water mixed with skimmed milk was excellent in (49) days of age in comparison with other groups in days ( 21 , 35 ) with range moral different in probability of (0.05 >P). The 4th group that used of eye drop vaccination was in second order , the third group that used of spray vaccination in third order while the 2nd and 5th groups were somewhat similar in result and there was no moral different.We concluded that the vaccination by using of drinking water that consist of tap water mixed with Skimmed milk was the best methods and gave an important satisfactory results in comparison with other methods. The ELISA test have high efficiency and best than HI test in detection titers of Newcastle disease antibodies due to the test sensitivity in measurement of IgY present in vaccinated chicks serum while the HI test didn’t reach the same sensitivity of ELISA test in complete detection of this immuno globulin ( IgY ).

الكشف السيرولوجي والجزيئي لفايروس مرض الحمى القلاعية في الابقار في محافظة البصرة Serological And Molecular Detection of Fmdv In Cow of Basrah Province

اسم المؤلف: زينب مجيد سالم الكلي
اسم المشرف: عدنان موسى الروضان
الموضوع العام: الطب البيطري
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: اجريت هذه الدراسة في6 مناطق مختلفة ( شط العرب والزبير والقرنه وابي الخصيب ومركز البصره والمدينه) ممثله لجميع اجزاء محافظة البصره خلال الفتره من شهر تشرين الاول من العام 2012 الى شهر تموز من عام 2013 ولتحديد نسبة انتشار مرض الحمى القلاعيه في الابقار استخد | This study was conducted on local cattle from 6 different regions (Shutt - Alarab,Al - Zubair, Al - Qurna, Abi - Elkhasib, Basrah center and Almdaina) covering all parts of the Basrah province during the period from October 2012 to July 2013. In order to determine the prevalence of foot and mouth disease in bovine species Enzyme Linked Immune Sorbent Assay ( ELISA) and reverse transcriptase polymerase chain reaction techniques( RT - PCR) were used in the testing of serum ,saliva and vesicular fluid samples collected from clinically diseased cattle, moreover this study was also mentioned some clinical aspects of the disease.Diseased animals showed the following clinical signs : depression(92.1%),sever salivation(90.9%) ,vesicles in mouth(90.3%), fever(89.1%) , conjunctivitis(87.9%) and smacking of lips in higher rates( 80.6%).While the vesicles on teat(12.7%), lameness(36.9%)and vesicles on feet (45.5%)appeared in lower rates.The overall prevalence of this disease was(72.7%.).Of 165 serum samples subjected to nonstructural protein (NSP) ELISA screening test (ELISA CHEKIT FMD - 3ABC Bo - Ov ELISA Test ) , 120 were interpreted as positive representing (72.7%.) while the other 45samples were negative representing 27.3%.The seropositivity significantly associated with age groups (p<0.01) and sex (P < 0.01).Depending on sex of these animals , the higher seropositivity rate was observed in females (78.6%).Concerning the age of tested cattle the animals of 2nd age group (>4 - 8 years) appeared in higher rate (84.8 %) of seropositivity followed by the rate (51.7% ) of 1st age group animals(<1 - 4 years).The sero - positivity against FMDV was non significantly different(>P 0.05)among the cattle in Basrah districts and highest sero - prevalence rate was observed in cattle of Basrah center (100%), Al - Mdaina (77.8%), Shut - Alarab(76.3%) and Abi - Elkhasib (70%).The lower sero - positivity rate was observed in Qurna(58.8%)and Zubair (50%) cattle.RT - PCR detection of FMDV for primary and serotype specific diagnosis was used. of eighty three clinically positive samples including, mouth vesicles, saliva and serum samples tested by RT - PCR, only 68(81.9%) were successfully amplified, their identification was done with universal primer sets (1F / 1R, )with expected band of( 328 bp).Of sixty eight universal primer based RT - PCR positive samples tested for serotype A - 1C562(865bp), O - 1C272( 635bp ) and Asia1 - 1C505(911bp) serotypes primers, 19(27.9%) samples were found to be serotype A - 1C562 positive and 26(38.2%) were serotype O - 1C272 positive and nil for Asia1 - 1C505 serotype. The frequency of foot - and - mouth disease viral genome presence in cattle had significant differences concerning the sex (P<0.05) while the difference among age groups was highly significant (P < 0.01) in case of universal gene and not significant(P>0.05) in case of all serotypes genes. Depending on the sex effect, the rate of RT - PCR positive results of universal gene and O - 1C272 serotype gene were higher in females (87.5 and38.8% respectively ),while A - 1C562 serotype RT - PCR positivity rate was higher in males (31.6% ).Different rates of RT - PCR positivity was observed in the two age groups of cattle and the second age group(>4 - 8 year) showed higher rate of positivity as a follow : (universal primer (90.7%),O - 1C272 serotype primer( 40.8%) and A - 1C562 serotype primer(34.7% ).In the studied regions of Basrah province , the FMDV genes were significantly(P<0.05)distributed. The rates of universal gene appearance were100, 93.3 and 83.3%of cattle in Zubair ,Qurna and Shutt - Alarab respectively. The serotype A - 1C562 was distributed in higher rate ( 100 and 40%) of Zubair and Al - Mdaina cattle respectively , while the serotype O - 1C272 was observed in higher distribution rate in cattle of Abi - Elkhasib (44.4%) and Qurna(42.9%), so there is significant differences ((P<0.05) according to distribution of serotypes of FMDV of regions of Basrah province.

دراسة سريرية وتشخيصية لنقص بعض العناصر النادرة في الاغنام في البصرة Clinical And Diagnostic Study For Some Trace Elements In Sheep In Basra

اسم المؤلف: بهجة غسان طالب
اسم المشرف: اسراء عبد الودود السعد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الطب الباطني والوقائي
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: صممت هذه الدراسة لتحديد نقص النحاس, الخارصين, والكوبالت في الاغنام في محافظة البصرة حيث تم فحص 1400 حيوان ,جمعت النماذج من اربع مناطق مختلفة (شمال, شرق, غرب, وجنوب) من المحافظة ومن خلال الفحص السريري للحيوانات, اظهرت 200 (14.2%) علامات سريريه و25 حيوان كا | The present study was planned to determine the deficiency of copper, zinc and cobalt in sheep serum in Basra province. 1400 sheep were inspected, then samples were collected from 225 sheep from different areas (North, East, West and South). 200 (14.2%) sheep showed a clinical signs, while 25 were clinically normal. The clinical examination was conducted on the sheep that were suspected to have mineral deficiency. In addition, hematological examinations were carried out including (Red Blood Cell Count "RBCc", Packed Cell Volume "PCV", Hemoglobin Concentration "Hb"), The concentrations of copper, zinc and cobalt were tested in the serum samples, and the concentration of (Superoxide dismutase "SOD" and Ceruloplasmin "CP" ) were tested as well. The result of clinical examination, showed there were alopecia (47.5%), parakeratosis (18%), diarrhea (11.5%), pale mucus membrane (49%), lacrimation (6%) and ataxia (4%). The mean value of temperature was within the normal value (39.47±0.33 C?) while there were increased mean values in pulse rate and respiratory rate (33.99±0.29 /Min and 90.48±4.53 Min) respectively in the affected sheep compared to that of the clinically normal.The hematological parameters showed significant decrease in RBCc (6.57±0.10*106/?l), PCV (19.75±0.24 %) and Hb (6.88±0.11 g/dl) compared to that of the clinically normal.The concentrations of copper, zinc and cobalt in the affected sheep were (0.15±0.00 ppm, ppm 0.73±0.03, 0.57±0.01ppm) respectively, which were less than the normal compared to that of the clinically normal.The present results revealed that the concentration of superoxide dismutase and ceruloplasmin enzymes in serum were significantly low in affected sheep compared to that of the clinically normal (P<0.05). The present results revealed a positive non - significant (P>0.05) correlation for copper with zinc and cobalt. While zinc was correlated negatively with cobalt.The present study has revealed that the concentration of SOD correlates positively with copper and zinc at (P>0.05). While there was a significant positive correlation between CP and copper (P>0.05).

التهاب الامعاء التنخري في الدواجن الامراضية, وطرق السيطرة والعلاج Necrotic Enteritis In Poulry Pathogenesis, Prevention And Curative Measures

اسم المؤلف: سهى نجم الربيعي
اسم المشرف: علاء عبد العزيز عبد
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الامراض - الدواجن
الدرجة: دبلوم عالي
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:

تاثير بعض معطلات الغدد الصم على بعض المعايير الفسلجية والتغيرات النسجية في ذكور الجرذان البالغة Rattus norvegicus The Effect of Some Endocrine Disruptors On Some Physiological Parameters And Histological Changes In Adult Male Rats “ Rattus Norvegicus“

اسم المؤلف: سارة جعفر سعدون الازيرجاوي
اسم المشرف: جاسم محمد احمد الكلبي
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الفسلجة
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: اجريت الدراسة الحالية في البيت الحيواني لكلية الطب البيطري / جامعة البصرة خلال الفترة الممتدة من 22/2/2013 الى 1/6/2013. لتقييم التاثيرات الصميه والتكاثرية لمعطلات الغدد الصم وايجاد الرابط بينهما في الذكور البالغة. استخدم في هذه الدراسة عقارين : بروبيل | The present study was carried out in the animal house of the College of Veterinary Medicine /University of Basrah during the period extending from 22/2/2013 to 1/6/2013. To evaluate the endocrine and the reproductive effects of endocrine disruptors chemicals and find the link between them in adult male rats. This study was done using two drugs : propylthiouracil (PTU) and flutamide (FLU) (anti - thyroid and anti - androgen agents) respectively, as a model of endocrine disruptors; to reveal their effects, they were used separately and in co - treatment manner for the first time using adult male rats (Rattus norvegicus) as animal models. For this purpose the study was divided into two experiments : The first experiment : forty adult male rats weighed (146 - 200) gm were divided into four equal groups (10 rats/group). The first group (control) was administered 0.3 ml/rat of distilled water, the second group was administered (PTU) (15mg/ kg B.W), the third group was administered (FLU) (37.5 mg/ kg B.W), and the fourth group was administered (PTU+ FLU) (15mg/kg + 37.5 mg/kg B.W ) respectively, in co - treatment dose. The treatments extended for 45 days; in the end of experiment the rats were euthanized and blood was collected and stored for hormonal and biochemical parameters and some of internal organs were weighed and kept in 10% formalin for histological examination. The results of the first experiment revealed the following : 1 - A significant decrease (P?0.05) in body weight gain in 2nd and 3rd periods (The animals were weighed four times in the begining of the experiment and every 15 days till the end of the experiment) in PTU and PTU+FLU treated groups.2 - A hypothyroidism state were induced after treatment with PTU and PTU+FLU by significant decrease (P?0.05) of Thyroxine (T4) and Triiodothyronine (T3) and significant increase (P?0.05) of TSH.3 - A significant decrease (P?0.05) in testosterone (T), Follicle Stimulating Hormone (FSH), and Luteinizing Hormone (LH) of PTU group while a significant increase (P?0.05) in T, FSH, and LH of FLU group. Moreover a significant decrease (P?0.05) in T and LH of PTU+FLU group occurred.4 - A significant increase (P?0.05) in Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) in all treatments, except in FLU no significant change has been observed in ALT. 5 - A significant increase (P?0.05) in total cholesterol, triglycerides, low density lipoprotein and very low density lipoprotein in all treatment, while, there was a significant decrease (P?0.05) in high density lipoprotein in all treatments as well.6 - A significant decrease (P?0.05) in serum glucose and a significant increase (P?0.05) in total protein in PTU and PTU+FLU groups, while, a significant decrease (P?0.05) in total protein of FLU group occurred.7 - A significant decrease (P?0.05) in sperm count of FLU and PTU+FLU groups. And a significant decrease (P?0.05) in individual motility in all treatments, while, a significant increase (P?0.05) in dead and abnormal sperm was observed in all treatments.8 - A significant increase (P?0.05) in thyroid relative weight of PTU and PTU+FLU groups and a significant increase (P?0.05) in liver relative weight in all treatments, while, a significant decrease (P?0.05) in kidney relative weight of PTU and PTU+FLU groups observed. Prostate relative weight significantly decrease (P?0.05) in FLU group and seminal vesicles relative weight significantly decrease (P?0.05) in FLU and PTU+FLU groups.9 - At the end of experiment six rats of each group was sacrificed and some of internal organs has been removed for histopathological examination and it was revealed changes as follows : 1 - Thyroid gland of PTU and PTU+FLU groups show increased number of different sizes of thyroid follicles with some vacuolation of colloid. Some follicles are misshaped. 2 - Testis of PTU group, most of seminiferous tubules are normal, a little number of them suffers from dilated lumen containing little number of spermatogonia and abnormal arrangement with degenerated Sertoli cells, little number of immature spermatid in the lumen, some vacuolation in the spermatogonia and edematous of interstitial tissue, FLU group shows clear degenerative changes in the Sertoli cells, there are few spermatogonia in some tubules and clear vacuolation in the cell with empty lumen (no spermatids). PTU+FLU group show most of the seminiferous tubules contain large number of spermatogonia but there are very thin irregular lining epitheliums, and nearly disappearance of interstitial tissue. 3 - Prostate of PTU group shows clear destructive changes in the lobules of the prostate. FLU group shows misshaped acini of the prostate lobules some of them are very enlarged and contain a large amount of secretion, others are empty with thickened irregular lining epithelium. Absence of inter acinar tissue, and PTU+FLU group show irregular shape of multiple number acini of the lobules of the prostate gland filled with shrinkage prostatic secretion. Moreover, the interstitial tissue between acini somewhat thickened with enlarged nuclei of many cells in addition to degeneration of others.4 - The liver of PTU group shows flattening of hepatocyte, clear enlargement of pyknotic nuclei and disarrangement of hepatic architecture, FLU show normal central vein, engorged with blood, disarrangement of hepatocyte architecture, and enlarged nuclei of hepatocyte. PTU+FLU show engorgement of central vein with clear flattening of hepatocyte containing enlarged nuclei.5 - The kidney of PTU group shows narrowing of lumen of renal tubules, engorgement of blood vessels, irregular sizes of glomeruli and different structure of their Bowman's capsule, FLU group shows a complete disappearance of Bowman's capsule of some glomeruli. Other glomeruli shows shrinkage and destructive changes of the content. The cuboidal epitheliums of the renal tubules shows some disarrangement of basement membrane with clear enlarged nuclei, and PTU+FLU group shows an irregular shape of renal tubules with absence of walls of the cuboidal lining epithelial cells with enlarged nuclei and shrinkage of Bowman's capsule of some glomerli. The second experiment : This experiment was carried out on 32 well experience female rats. They have been mated with 16 adult male rats which remained from the first experiment; they were divided into 4 groups : The first group : Untreated 8 female rats mated with 4 untreated male rats, the second group : Untreated 8 female rats mated with 4 treated male rats with PTU, the third group : Untreated 8 female rats mated with 4 treated male rats with FLU, the fourth group : Untreated 8 female rats mated with 4 cotreated male rats with PTU +FLU. The results of second experiment revealed a decrease in number of offspring as well as reduction in percentage of fertility and pregnancy rates.

دراسة مصلية لداء المقوسات في الجمال Serolgical Study of Toxoplasmosis In Camels

اسم المؤلف: سعيد محمد حسن حيدر المظفر
اسم المشرف: قاسم حليم كشاش
الموضوع العام: الطب البيطري
السنة: 2010
الموضوع الدقيق: الطب الباطني والوقائي
الدرجة: دبلوم عالي
الجامعة: جامعة البصرة
اللغة: العربية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: شملت الدراسة فحص مصول 334 جمل جمعت خلال الفترة من الاول من تموز - ولغاية نهاية شهر ايلول لعام 2010 متوزعة على 219 ذكر و115 انثى من الحيوانات الواردة الى مجزرة النجف الاشرف لغرض التحري عن الاجسام المضادة لطفيلي داء المقوسات باستخدام فحص تلازن اللاتكس Late | This study was conducted to examine serum of (334) Cameles in Al - Najaf slaughter house, which include (219) camel males and (115) camel females during the first of July until the end of September/ 2010 to investigate antibodies against Toxoplasmosis by Latex agglutination test as well as to estimate the levels of their antibodies by using semiquantative test.The total percentage of infestation 20.35%, and the sex has non significant on their infestation in examined camels (16.89%) in camel males and 26.95% in camel females.The highest percentage of seropositive with Toxoplasma is recorded in adult camels 23.33%, while it is (15.3%) in young camels.The results revealed that the highest titration of antibodies level was 32 (19.11%), and there is no significant effect of sex on antibodies level, while the age of examined camels was affect significantly.

تقييم مستوى بعض المعادن في الجاموس المحلي في محافظة البصرة Evaluation of Some Minerals In Buffaloes In Basra

اسم المؤلف: دنا حسن علي
اسم المشرف: محمد عبد الحسين يعقوب العامري
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الطب الباطني والوقائي
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: The present study was carried out to evaluate the levels of copper, zinc iron and calcium in buffaloes from different regions in Basra province /south of Iraq.Samples of serum were collected from (255) head of buffaloes, (20) multiple samples of soil from their pastures as well as (20) multiple samples of green forage grazed by the animals were also taken. Samples of serum, soil and forages were prepared and digested by acids then minerals were estimated by the method of atomic absorption spectrophotometer.All animals of the study were clinically examined to record the signs of mineral deficiency including alopecia, discoloration of the coat, emaciation, parakeratosis, abortion and abnormal gait, in addition to the vital signs(temperature of the body, pulse and respiratory rate). Two hundred seventeen buffaloes with characteristic clinical signs of mineral deficiency and thirty eight clinically healthy buffaloes which recommended as a group of control were selected while buffaloes those suspected to have infectious diseases were neglected.According to the results, the first group 38(14.9%) which was clinically healthy , revealed the highest levels of copper, zinc, iron and calcium and as the following (70.3±0.867, 154±4.459, 320±2.844) ?g/dl, and (9.9±0.106) mg/dl, respectively. The second group 217(78,4%) which characterized by clinical signs of mineral deficiency had significantly lower (p<0.05) levels of copper, zinc, iron and calcium in comparison with the first group and as the following (48.4±3.040 , 79±0.639 , 276±4.011) ?g/dl and (7.6±0.316) mg/dl respectively.It was evidenced from the examination of soil that the levels of copper, zinc, iron and calcium were (0.20 ±0.039, 0.72±0.032, 5.8±0.389 and 575.1±26.704) ?g/g respectively, and these results sign to the presence of the deficiency in copper and zinc while the levels of iron and calcium were in the normal limit of them in the soil.In relation to green forage, the levels of copper, zinc, iron and calcium were(2.3±0.269, 23.8±0.486, 25.5±0.641)?g/g, and (0.35±0.110) g/100gm respectively, and these results revealed a deficiency in the levels of copper, zinc and iron while the level of calcium was within the normal limit of it in the green forages.

التحري عن داء المقوسات في النساء والنعاج بواسطة طرق مصلية مختلفة في محافظة ميسان - العراق An Investigation of Toxoplasmosis In Women And Ewes By Different Serological Assays In Maysan Governorate, Iraq

اسم المؤلف: مرتضى شهاب جبار
اسم المشرف: منى محمد جوري
الموضوع العام: الطب البيطري
السنة: 2013
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: تم جمع 291 عينة من الدم الوريدي من النساء في سبعة مناطق مختلفة في محافظة ميسان للفترة من تشرين الثاني 2012 وحتى اذار 2013 للكشف عن داء المقوسات باستخدام ثلاثة اختبارات هي اختبار التلازن الحبيبي وانزيم الادمصاص المناعي واختبار المنفايدس ثلاثة مجاميع من الن | In this study, venous blood sample were collected from 291 women in seven different regions of Maysan province during the period from October 2012 to March 2013 for detecting the toxoplasmosis by using three tests (Latex agglutination (LAT), enzyme linked immunosorbent (ELISA - IgG) and minividas. Three groups of women ( pregnant ,non - pregnant and aborted ) and 283 ewes which represent 18 herds from nine regions of Maysan province were selected for the study in order to diagnose the toxoplasmosis by using ELISA and LAT tests. The results showed that the ratio of Toxoplasma seropositivity in aborted women was significantly the highest (69.23%) followed by pregnant group (60.16%) by using LAT. Moreover, the ratio of seropositivity was highest in aborted women (47.43%) followed by pregnant (36.58%) and non - pregnant (26.66%) groups, respectively by using ELISA test. With Minividas assay, the results showed the highest seropositivity percentage in aborted women (26.92%) followed by the pregnant (17.88%) and non - pregnant (11.11%) groups, respectively. According to regions of the study, there was higher seropositivity against T. gondii in women in Al - Musharah subdistrict by LAT (68.09%) and ELISA (44.68%) test, respectively. However, the seropositivity by using minividas assay in three regions in AL - Majar district, Al - Musharah subdistrict and AL - Maymona district were 23.52% , 23.40% , 23.52% , respectively in comparison with other regions in Maysan governorate. The significantly high (P? 0.05) seropositivity detected by LAT (72.63%), ELISA (50.52%) and minividas (28.42%) were in women of age group > 30 years. The results showed that the ratios of Toxoplasma seropositivity in aborted ewes group was the highest (73.33%) followed by pregnant group (65.38%) after using the LAT, while the seropositivity in aborted ewes detected by the ELISA test was 40%. The results from Al - Musharah subdistrict that showed highest seropositivity against Toxoplasma by using LAT and ELISA tests were 78.26% and 39.13%, respectively. The highest Toxoplasma seropositivity in the two - years age - group ewes was 65.57% and one - year age - group was 65.30% after using LAT test, while was 32.65% in the age - group more than a year by ELISA. The statistical analysis showed significant difference (p ? 0.05) between the LAT and ELFA tests conducted for women samples, but there were no significant differences (p? 0.05) between LAT and ELISA carried out for women and ewes samples with regarded to Toxoplasma seropositivity.

عزل وتشخيص جرثومة ال (Pasteurella multocida) من الابقار والاغنام وتصنيف انماطها المصلية باستخدام تقنية تفاعـل السلسلة المتبلمرة Isolation And Diagnosis Pasteurella Multocida From Cattle And Sheep And Serotyping Classification Using Polymerase Chain Reaction Technique

اسم المؤلف: جنان ناظم صادق العبيدي
اسم المشرف: عدنان حمد عبيد الحمداني قاسم حليم كشاش
الموضوع العام: الطب البيطري
السنة: 2012
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: تضمنت الدراسة جمع 150 نموذج من الرئات المصابة والمسحات الانفية ومسحات اللوزتين من الابقار والاغنام للمدة1 / 11 / 2010 ولغاية1 / /4 2011 من حظائر حيوانية ومجازر مختلفة في مدينة الديوانية. تم زرع العينات على ( وسط اكار الدم ووسط الماكونكي واكار تربتون الص | The study included the collection of (150) samples of infected lungs and nasal , tonsils swabs from cattle and sheep at the period 1/11/2010 to 1/ 4/2011 of farm animals and various massacres in the city of Diwaniya. Samples were cultured on the blood agar and MacConkey agar and Trypticase Soya agar then diagnosed after pure isolation of colonies of pasteurella multocida were diagnosied and identified using morphological and biochemical features. The results revealed that the total isolation percent of Pasteurella multocida was 82(54.6%) which distributed as 40(53%) and 42(56%) for cattle and sheep ,respectively.on the other hands ,the high percent of isolation were recoverd from infected lungs 16(64%) followed by tonsils 13(52%) then nasal swabs 11(44%) in respect with cattle ,while in sheep ,the percent were 17(68%) for infected lungs ,11(44%) for nasal swabs and 14(56%) for tonsils swabs The percent of P.multocida isolation in cattle was 28(51.8%) in age group (>2years)while it was 12(57.1%) in age group (<2years),where as these percents in sheep were 27(56.2%) and 15(55,5%) ,respectively. In male ,the percent of isolation were 22(45.8%) and 20(54%) in females in respect with sheep samples ,while it was 21(51.2%) and 9(55.81%) in cattle respectively ,there was no significant differences (p>0.05) between isolation percent according to species ,sex and age of animals. The results of polymerase chain reaction (PCR) as confirmatory test for P.multocida isolates after DNA extraction and amplification with specific primers named KMT - 1 showed asingle band amplified DNA with amolecular weight of 460 bp. In purpose of serotyping the isolates of Pasteurella multocida by using PCR, the specific primer of capsule ( CAPA, CAPB, CAPD, CAPE, CAPF) were amplified the results revealed that the serotype (B) was the dominat in cattle , with molecular weight (760pb) while type ( A) the dominat in sheep with molecular weight (1044pb). In Coclusion , the result of molecular diagnosis of P.multocida serotyping by using PCR revealed ahigh specificity (84.5 %) sensitivity (97.05%) in Comparision with routine diagnostic of this bacteria in cattle and sheep.

التحري عن الاصابة بفيروس جدري الابل في بعض محافظات العراق باستخدام تقنية تفاعل سلسة انزيم البلمرة PCR

اسم المؤلف: محمود شاكر عبد الامير عيدان مرزوق
اسم المشرف: هدى عبد الهادي علي النصراوي
الموضوع العام: الطب البيطري
السنة: 2012
الموضوع الدقيق: الامراض المشتركة
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:

تاثير نخاع العظم وحامض الهيالورونيك في اصلاح وتر القابضة الاصبعية السطحية المرفو في الحمير Effect of Bone Marrow And Hyaluronic Acid Bioscaffold of Repair of SDFT Tenorrhaphy In Donkeys

اسم المؤلف: حميد عبد غاطي
اسم المشرف: عبد الباري عباس ساهي الفارس
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الجراحة
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: The study was designed to assign the effectiveness of bone marrow and hyaluronic acid to repair of experimentally induced transected of the SDFT in donkeys by macroscopical, ultrasonical and histopathological evaluation.A total of 18 clinical healthy donkeys of both sexes with the age of 2 - 3 years weighting of 70 - 130 kg (mean ±SE, weight 97.77 ± 8.11 kg), were used for this study. The animals divided randomly into three equal groups (six animals/groups), the (group A) was used as a control group. The treatment groups were classified into and the bone marrow group (group B) and the hyaluronic acid group (group C) and the animals were generally anesthetized.In all animals of this study a mid - metacarpal linear skin incision was made in the palmer aspect of the left forelimb, the SDFT then was transected transversely and then the cut ends of the tendon were approximated by (0.2) Nylon suture and skin closure by using (0.2) silk suture. In group (B), two ml of bone marrow was applied to the sites of anastomoses tendon. In group (C), use a two ml of sodium hyaluronate on the sites of anastomoses tendon.Macroscopical examination showed adhesions between the tendon and surrounding tissues which were severe in the group (A) than in group (B) and lesser than that in group (C).Histopathological findings with the group (A) showed edematous fluid and collagen fiber in 30 days postoperatively and the presence of the edema and irregular collagen fiber were observed at day 60th. In group (B) showed a marked increase in neo blood vessels (angiogenesis) and collagen fiber in 30 days postoperatively and observed a moderate number of new blood vessels and collagen fibers at 60 days postoperatively.In group (C) demonstrated a numerate new blood vessels ,the collagen fiber and edema at 30 days postoperative and the prominent fibroblast at 60 days postoperative.Ultrasonographic examination for the tendons of the group (A), 30 days postoperatively showed the presence of marked fluid in SDFT with anechoic over the site of operation (dark area) while, 60 days postoperatively there is moderate fluid the SDFT appear as area of anechoic to hypo echoic.In tendons of group (B) in 30 days postoperatively notice the presence of lesion in a tendon, which appear as hypo echoic area with slower to demonstrate evidence of healing on ultrasound. In 60 days post operatively there is corresponding longitudinal fiber, alignment grade with hyper echoic appearance of operation area. In tendons of group (C) in 30 days postoperatively ultrasonography shows the presence of moderate fluid and the hypo echoic area within the SDFT. In 60 days postoperatively notice the presence of mild fluid in the site of operation that reflected as hypo echoic to hyper echoic area.The results of this study demonstrated the effectiveness of (Bone marrow) in acceleration the process of tendon healing and reducing fibrous adhesions that occur after the exposure of the tendon to injury compared to the (Hyaluronic acid), which has the same effect but to a lesser extent

استخدام حليب الافراس المخمر في علاج قرحة المعدة المستحدثة بالاسبرين في اناث الجرذان البيضاء Usage of Fermented mareP,Ps Milk In Treatment of Aspirin Induced Ulcer In Female Albino Rats

اسم المؤلف: اسراء طاهر مسلم العبيدي
اسم المشرف: كريم ناصر طاهر علي محمد غازي
الموضوع العام: الطب البيطري
السنة: 2015
الموضوع الدقيق: الصحة العامة
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: This study was carried out at the animal house of veterinary medicine College /AL - Qadisiya university during the period from 27 - 6 - 2014 to 27 - 3 2014 the study aimed to investigate the effect of usage fermented mareP P s milk on the healing of gastric ulcer induced by aspirin. A total of 56 female albino rats weighing between 200 - 250g were used in this study.. The animals were divided randomly in to four equal groups each groups comprising of 14 females per each group.Untreated group or negative control groups (C) : were received standard diet and distilled water only.treated groups : - positive control group (T1), second treated group ( T2) and Third treated group (T3). All animals of these groups were induced ulcer by administrated orally(100mg/kg b.w ) aspirin drug for one week ,Then two animals from each group were sacrificed after 7 days to ensure that ulcer induced,after that the animals of second treatment group(T2) were given orally by gavage fermented mare P Ps milk at dose(10ml/kg b.w) once daily for three weeks consecutive while animals of third treatment group (T3) were treated oraly by gavage rantidine (50mg/kg b.w) once daily for three consecutive weeks, four animals per each group were sacrificed at the end of each week، and the stomach were excised to measures the ulcer parameters (ulcers score, ulcer index,ulcerinhibition percentage and PH of gastric juice value) blood samples were collected from all animals from the heart for blood test parameters (red blood cell count , hemoglobin concentration and packed cell volume).Biochemicals parameters such as alanine trans amines(ALT), aspartate trans amines(AST),alkaline phosphatase (ALP) total protein ,urea and creatinine and oxidative stress parameters such as malondialdehyde (MDA), superoxide dismutase(SOD),glutathione, (GSH), and prostaglandin (PGER2R).in addition tohistological examination to ensure the exist of ulcer. The results of this study revealed the following : ulcer parameters : the result of this study revealed that administration of aspirin produced formation multi - ulcer in the stomach wall besides causes different changes in the studied parameters al so, the result has been shown a significantly ( P<0.05) increase in the ulcer score and ulcer index in aspirin administration groups (T1)in Comparison with other experimental groups during the three weeks of the experiment on the other hand aspirin administration causes a significant (P<0.05) reduction in pH value of gastric juice , at the same time given fermented mare ,s milk improvement for the previous parameters and causes a significant (P<0.05) decrease in it along the three weeks of experiment as well as causes a significant (P<0.05) increase in ulcer inhibition ( %) and the pH value of gastric juice ,these values were closed to the values of ranitidine treated group (T3) and control groups respectively.Blood parameters : the result of the present study revealed that there was a significant ( P<0.05) decrease in the total count of RBC ,Hb concentration and PCV in aspirin administration group (T1) as compared to the other experimental group along the three weeks of experiment. while given fermented mar P Ps milk causes improvement in the previous parameters and produce a significant (P<0.05) increase of these parameters and became close to the values of rantidine groups and negative control groups.Biochemicals parameters : The result indicated that administration of aspirin produced a significant (P<0.05) increase in ALT,ASTand ALP activity as compared to the othe experimental groups but causes a significant (P<0.05) decrease in concentration of total protein particularly in the third weeks of experiment ,while giving fermented mare P,Ps milk causes improvement the previousparameters and causes a significantly (P<0.05) reduction in it and became close to the values of rantidine groups and negative control groupsOxidative stress parameters : the result of the present study revealed that there was a significantly( P<0.05) increase in (MDA concentration) and significantly( P<0.05) decrease in the concentration of (SOD,GSH and PGE2) in aspirin treated groups ,while giving fermented mare ,s milk causes a significantly( P<0.05) decrease in concentration of MDA and a significantly (P<0.05) increase in the concentration of( SOD ,GSH ,PGE2) these result are closed to the result of rantidine treated groups and negative control group.the result also shown there were non significant differences in concentration of urea and creatinine along experimental weeks among different groups ,on the other hand, the results of the histological examination of aspirin treated groups that a pathological changes in the stomach tissue represented in formation ulcers , congestion and bleeding.while giving fermented mare's milk contributes in the active form in hide of ulcers in the stomach wall, hemorrhage signs and congestion similar results obtaining when treated with rantidine.it could be concluded that aspirin administration causes negative effect on stomach also the study has been showed the important role of fermented mare's milk in reduction damages and negative effects of aspirin.

تاثير التمنيع الميسر ضد وحدات الانهبين الفا وبيتا اي وبيتا بي في نمو وتطور الغدة اللبنية لاناث الجرذان Effect of Passive Immunization Against Inhibin - ?, ?A, or ?B Subunits On Mammary Gland Growth And Development In Female Rats

اسم المؤلف: منهل جبار عبد السعيدي
اسم المشرف: جبار عباس احمد الساعدي جاسم محمد احمد الكلبي
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الفسلجة
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: هنالك علاقة وثيقة بين اعضاء عائلة عوامل نمو بيتا الانتقالية TGF - ? مع توجيه الاحداث المتعلقة بالتكاثر. اجريت الدراسة الحالية في قسم الفسلجة بكلية الطب البيطري في جامعة البصرة خلال المدة بين شهر نيسان، 2013 وكانون الثاني، 2014، لاختبار دور التمنيع ضد وحد | The present study, which has been carried out at the department of physiology, College of Veterinary Medicine, University of Basrah, during the peroid extended from April, 2013 to May, 2014, has been designed to examine the role of immunoneutralization of endogenous inhibin - ?, ?A, and ?B subunits on mammary gland growth and development in primiparous female Wister rats, by evaluating serum growth and differentiation hormones, expression levels of pituitary GH and PRL, and mammary GH - r and PRL - r genes, and immunohistochemical expression of pituitary somatotrophic and lactotrophic cells, and mammary GH and prolactin.Eighty four pregnant female rats were randomly divided into four groups (21 per each). On 5th and 10th day of gestation, control was injected with saline (100?l, i.p.), Ta group was injected with inhibin - ? antiserum (1µg in 100?l of saline, i.p.), Tba group, was injected with inhibin - ?A antiserum (1µg in 100?l of saline, i.p.), and Tbb group was injected with inhibin - ?B antiserum (1µg in 100?l of saline, i.p.). Each group was allocated to 3 equal subgroups : pregnancy, delivery, and lactation subgroups was sacrificed on the 16th day of gestation, on the 1st day after parturition, and the 11th day of lactation, respectively. Body weights of females have been monitored during pregnancy. At parturition and 11th day of lactation, litters weight have been recorded. At the end of each subgroups period, females were anesthetized, dissected and blood samples were obtained for assessment of inhibin - A, - B, activin - A , - B, - AB, GH, and prolactin levels. Pituitary and mammary glangs from each female were removed for evaluation of expression levels of GH, PRL, GH - r, and PRL - r genes using qRT - PCR technique and other samples for histophysiological and immunohistochemical study.The results demonstrate significant increase in cumulative dam weight in Tba group during pregnancy period starting from 8th of gestation compared with control, Ta, Tbb groups. Litters of Ta group at parturition, revealed siginificant higher weight compared with Tba group, and no siginificant difference compared with control and Tbb groups. Litter of Tba group recorded a highest siginificant weight gain among experimental groups.Serum inhibin - A in Tbb group during pregnancy, recorded higher level among experimental groups. During delivery, the higher significant level has been registered in control and Tbb groups. During lactation, no siginificant difference has been recorded between groups. In comparison between periods, the level in control during delivery showed the higher level compared with pregnancy and lactation periods, whereas Ta and Tba groups recorded no difference between periods, while Tbb group showed significantly higher level during pregnancy and decreased during delivery and lactation. Inhibin - B during pregnancy in control females recorded the highest level among the experimental groups. During delivery, higher levels have been recorded in control and Tba groups. At lactation, there is no siginificant difference between Ta, Tba, and Tbb groups but they were significantly higher than control. In comparison between periods, the concentration in control during pregnancy recorded higher level than other periods. Ta, Tba, and Tbb groups recorded no siginificant differences between pregnancy and delivery periods but they were significantly higher in lactation period.Activin - A concentration during pregnancy and delivery in Tbb was higher among experimental groups. During lactation, there is no difference between experimental groups. In comparison between periods, all groups showed higher levels at delivery. Activin - B during pregnancy and delivery in Tbb group recorded the lowest concentration. During lactation, no differences has been shown between groups. In comparison between periods, the levels in all groups was higher at lactation followed by pregnancy period and delivery periods. Activin - AB concentration in control and Ta groups were higher during pregnancy and delivery periods, while no siginificancy was recorded during lactation. In comparison between periods, all groups showed higher levels at lactation period followed by pregnancy and delivery periods.Serum GH in Ta group during pregnancy recorded higher level among groups During delivery, the higher level has been recorded in Ta and Tba groups. During lactation, the higher level has been recorded by Ta group among groups. In comparison between periods, the levels in all groups were higher at delivery followed by pregnancy and lactation. Serum prolactin during pregnant, delivery, and lactation showed no siginificant difference between experimental groups. In comparison between periods, the levels in all groups showed higher levels at delivery followed by lactation and pregnancy.Result of pituitary GH gene expression levels in Ta and Tba groups increased significantly compared with Tbb in all of studied periods.Result of pituitary PRL gene expression levels during pregnancy increased siginificantly in Tba group among experimental groups. During delivery, the fold changes in Ta and Tba groups showed no significant difference between each other, but they were significantly higher than Tbb group. At lactation period, there is no siginificant difference between groups.Result of mammary GH - r gene expression levels during pregnancy and delivery registered siginificant elevation in Ta, whereas lactation period showed no siginificant difference between groups. Mammary PRL - r gene expression levels during pregnancy was higher in Tbb group, whereas delivery and lactation showed siginificant elevation in Ta and Tba groups.Expression of pituitary somatotrophic cells during pregnancy showed significant higher score (number of positive stained cells and intensity of staining) in Ta group among the experimental groups. At delivery and lactation, scores of Ta and Tba groups, increased significantly. In comparison between periods, in all groups, higher score has been shown at delivery, whereas the lowest score recorded at lactation. Expression of pituitary lactotrophic cells during each periods showed no difference between groups. In comparison between periods, in all experimental groups, higher score of staining was recorded at delivery and lowest score recorded at pregnancy.Expression of mammary GH during pregnancy showed significant higher score in Ta group among the experimental groups. At delivery, the score of Ta group increased siginificantly. At lactation, Ta and Tbb groups registreted no siginificant difference between them, whereas they were siginificant higher than control and Tba groups. In comparison between periods, in all groups, higher scores have been shown at parturition and the lowest at lactation. Expression of mammary PRL during pregnancy and lactation revealed no siginificant difference between experimental groups. In comparison between periods, in all experimental groups, higher score of staining has been shown at delivery, whereas the lowest score recorded at pregnancy.Histological findings in treated groups, pituitary sections reveals progress in the morphological appearance of secretory cells which appeared larger and contains profuse cytoplasmic secretory granules. Ta females reveals more proliferation and cytoplasmic secretory granules. These differences continued at delivery and retarded at lactation. Mammary glands of treated groups at pregnancy showed marked development in alveolar morphogenesis. At delivery, Ta and Tbb females showed high number of lobules and alveoli. Lactation period showed well - developed vacuolated epithelial cells.In conclusion, passive immunization against inhibin - ?, ?A, subunits but not ?B subunit, at 5th and 10th day of pregnancy, have potent role in mammary gland growth and development in primiparous female Wister rats.

التحري عن بعض عوامل الضراوة للزائفة الزنجارية المعزولة من الحليب الخام والجبن الطري Detection of Some Virulence Factors of Pseudomonas Aeruginosa Isolated From Raw Milk And Soft Cheese

اسم المؤلف: عبد الكریم كاظم عبد الحسین الحسب
اسم المشرف: علي حسن احمد الشمري
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: صحة الغذاء
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: In order to detection of Pseudomonas aeruginosa in food - chain especially from Cows raw milk and soft cheese with its whey, this study was designed in some regions of Baghdad (College of Veterinary Medicine, Abu - Ghraib, Al - Sadrya & Al - Radwaniyah), in which a standard isolation methods were used with some modification processing by new, modern and rapid technology tools such as chromogenic medium CNP agar and Electronic rapid Microbact TM 24E panel identification system supported by standard color differential chart and online American Type Culture Collection (ATCC) Codes; aids in rapid and precise identification, differentiation, confirmation and enumeration of P. aeruginosa isolates from raw dairy samples; as well as, detection of biofilm producing versatile morphotypes with chameleon phenomenon and fruity odour; and demonstration the activity of food spoilage enzymes (protease, lipase & lecithinase) of isolates with thermo - stability and viability in different temperatures with bitty cream and ropy fermentation phenomenon. The results profile showed : 1. Isolation of 46 (76.7%) isolate of P. aeruginosa from a total of 60 Cow Dairy samples : 30 Raw Milk samples (pooled from milk cans and apparently healthy Cows with a history of mastitis cases) as 19 (31.7%) isolates from regions of College of Veterinary Medicine, Abu - Ghraib and Al - Sadrya (10 from each region); and 30 Soft Cheese with its Whey samples (pooled from unhygienic processed cheese and containers in unclean dirty environment and apparently carrier or diseased workers) as 27 (45%) isolates from regions of Abu - Ghraib, Al - Sadrya and Al - Radwaniyah (10 from each region). Isolation percentages of oxidase positive P. aeruginosa from selected Regions in Baghdad Province indicates significant differences among regions at a level (P?0.05), in which highest isolation percent of P. aeruginosa from Abu - Ghraib as 20 (33.4%) isolates (10 isolates from raw milk and 10 isolates from soft cheese) in accordance to 17 (28.4%) isolates from Al - Sadrya (9 isolates from raw milk and 8 isolates from soft cheese), 9 (15%)SUMMARYisolates from Al - Radwaniyah (9 isolates from soft cheese) without any isolate from College of Veterinary Medicine, which may indicate good hygienic measurements.2. Segregation of isolates into two Haemolytic Patterns : Livestock type origin, lysis only sheep blood (L - type) as 19 (41.30%) isolates from raw milk samples; and Zoonotic type lysis, both blood (Z - type) as 27 (58.70%) isolates from soft cheese with its whey as high prevalence due to critical processing chain, risky carrier individuals and contaminated environment or polluted water supply. This may indicate indirectly genetic diversity and host or cross individual tropism in haemolysins - phospholipases activity according to different types of samples, regions and hosts.3. The study revealed isolation and segregation of versatile morphotypes and five pigments with fruity odor (Chameleon phenomenon) with mucoid drippy due to alginate or small colonial variants smooth or rough or both especially in isolate code M7 from mastitic milk and isolate code C27 from contaminated soft cheese and its whey. Wrinkled - Corroded green morphotypes were more evident in blood agar due to secretion of siderophore pyoverdine in order to chelating iron for activation of isolate. Motility Pattern with TTC salts was evident in all isolates with three types of motility : swarming, swimming and twitching, that noticed obviously in M7 isolate.4. New technology biochemical identification panel system (Microbact TM 24E) confirm that isolates were P. aeruginosa at level (P?0.01) after online matching with standard Remel ATCC Octalcodes bank of P. aeruginosa, in which 5 octalcodes typical and atypical were documented, that indicate genetic diversity in biochemical reactions of isolates and their morphotypes, modified microbial gene sharing protocol of P. aeruginosa with other bacteria and highly Sensitivity and Specificity of the test panel.SUMMARY5. Detection and isolation of Biofilm producing isolates by five methods, in which microtiter plate assay was the most sensitive and realizable technique while Congo red agar test detect quantity and type of biofilm production through colour of colonies (black very strong and huge, gray strong, pink moderate and white fair or non - producer). Biofilm produced in most morphotypes with pellicles at liquid interphase and ropy viscous threads (sliminess) and bitty cream especially in isolate codes M7 and C27. Small colonial variants of some morphotypes can revert to mucoid drippy variants. M7 showed unusual ropy thread of 30 cm long.6. The results showed secretion of thermo and psychro stable and labile food spoilage enzymes (protease, lipase and lecithinase) from isolates, in which versatile morphotypes showed indirectly diverse genetic ability, this may indicate variation of thermal tolerance mechanisms (heat shock proteins and biofilms formation) in isolates in accordance to time and temperature of processing, that linked genetically with the quorum sense mechanisms of acyl homoserine lactone gene regulatory region (AHL) in P. aeruginosa isolates (Stress Hardening phenomenon).7. The results showed the genetic ability (indirectly) of some isolates to resist, tolerate and proliferate in acidic environment at pH 2 & 4 especially isolate M7 & C27, while intermediate to susceptible tolerance of pH were noticed in others. This may indicate the power of electromagnetic charged net field of complex polymeric matrix of alginate exopolysaccharide layers in protecting some isolates from adverse acidic environment due to quorum sensing behavior of M7 & C27.Therefore, it could be concluded from this study that P. aeruginosa was prevalent in food chain especially from Cows raw milk and soft cheese with its whey samples from some regions in Baghdad, and Biofilm producing isolates with their thermo and psychro stable enzymes complex system and their tolerance to acidic environment stressors were more dangerous thus, we recommend monitoring these products periodically for insurance of public health.

الكشف الجزيئي والمصلي لداء المقوسات في الانسان والاغنام في محافظة واسط Molecular And Serological Detection of Toxoplasma Gondii In Human And Sheep In Wasit Province

اسم المؤلف: عباس حسن خلاطي السراي
اسم المشرف: نعمان ناجي عايز
الموضوع العام: الطب البيطري
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: اجريت الدراسة الحاليه خلال الفترة من تشرين الاول 2013 الى ايار 2014 في محافظة واسط للكشف عن الاصابة T. gondii في الانسان والاغنام باستخدام الطرق الجزيئية والمصلية. تم جمع خمس مئة وثمانية عينات 500 عينه دم و8عينات من انسجه المشائم و305 عينه 300عينه دم و5ع | The present study was conducted during the period from October 2013 to May 2014 in Wasit province to detect the infection of T. gondii in women and sheep using Molecular and Serological methods.Five hundred and eight samples 500 blood samples and 8placenta and 305samples 300 blood samples and 5placenta were collected from both suspected women and sheep respectively. The sera samples were separated and examined by ELISA for human and Latex agglutination test for sheep to detect the infection with T. gondii serologically, then many blood and placental tissue samples (89 blood samples and 8 placental tissue samples for women, whereas 100 blood samples and 5 placental tissue samples for ewes) were subjected to polymerase chain reaction (PCR) technique to detect the infection molecularly.The Serological results showed that 17.8% of women were positive for the private screening ELISA detects toxoplasmosis (17 % with chronic infection and 0.8% with acute infection), it was noted that the highest rate of infection was in women who ranged in age between 20 - 29 years, reaching 19.9%, but with no significant difference (P>0.05) between the ages studied. On the other hand the rate of sheep infection by latex agglutination test with 2 - mercaptoethanol amounted to 33.33% (31.33% with chronic infection and 2% with acute infection) and most positive cases were among the ages which were equal to or more than 3 years (?3 years) with significant difference (P<0.05) between these ages. The present study indicated a lack of months effect on the distribution of parasite infection rates where these different months recorded relatively close rate ranged between 14.45% - 23.07% in women and 31.42% - 35.97% in sheep with no significant difference (P>0.05).Regarding to polymerase chain reaction test, a fragment of 399bp was amplified from B1 gene, the result showed that 6.74% and 4% of blood samples and 100% and 80% of placental tissue samples which taken from women and sheep respectively were positive to this test.

تحديد القرابة الوراثية لعزلات عراقية ضارية لفيروس مرض النيوكاســــل من تتابع القواعد النتروجينية في موروث الهموكلوتنين نيورامنيديز Phylogenetic Determination of Newcastle Disease Virus Hn Gene Sequences Iraqi Virulent Isolate

اسم المؤلف: مرتضى عبد المهدي محمد حسن المظفر
اسم المشرف: هدى عبد الهادي علي النصراوي احمد مجيد حمزة الشمري
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الامراض المشتركة
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: يعد مرض النيوكاسل من اخطر الامراض الفيروسية المعدية التي تصيب قطعان الدواجن وتسبب خسائر اقتصادية كبيرة في صناعة الدواجن واول تسجيل لمرض النيوكاسل كمرض مشترك بين الانسان والحيوان كان من قبل العالمBurnet في سنة 1943. والهدف من الدراسة هو عزل وتحليل تسل | Newcastle disease is considered to be the most contagious poultry disease and may cause severe economic loss in the poultry industry. The first report in which Newcastle disease virus (NDV) was consider as zoonotic disease and a human pathogen that was published by Burnet, in 1943. The aim of this study was to isolate and determination of nucleotide sequence of the Hemagglutinin - neuraminidase gene (HN) of two NDV Iraqi virulent isolates. These isolates were named as Najaf isolate (Najaf APMV1/ Chicken/ Iraq - Najaf/ ICCMGR/2012) and Baghdad isolate (Baghdad ICCMGR). This work was conducted in Iraq for the first time, the reason behind it was to correlate phylogenetically between these two isolates and the NDV strains in the countries of the region. This will help in determining the source of NDV outbreaks occurred in Iraq. Both Najaf and Baghdad isolates were propagated in embryonated chicken eggs, after inoculation of 11 days embryonated chicken eggs was showed and embryos were killed in different times (more than 40 hours and less than 72 hours). To assess the activity of both virus isolates, the main features of the infected embryos that reflect characteristics of congestion and sever hemorrhage was compared with control one. Hemorrhage was markedly severed in the infected embryos and it was similar in its severity by both isolates. The allantoic fluid was harvested post infection and the agglutination activity reflected titer of 1024 for Najaf isolate and 512 for Baghdad isolate. In order to isolate the Hemagglutinin - neuraminidase gene (HN) from both Najaf and Baghdad NDV isolates, specific primers for this gene were designed. After viral RNA purification, one - step reverse transcriptase - PCR was undertaken to amplify the NH gene and isolated it from the gel. Nucleotide sequence of the isolated NH gene from both virus isolates was determined. The purpose was to focus on molecular and phylogenetic analysis of the hemagglutinin - neuraminidase (HN) gene in both Iraqi isolates. The resulted nucleotide sequence of 647 nucleotides of the HN gene for both isolate were submitted to the GenBank database under the accession numbers KJ632972. To determine the origin of both Iraqi virulent isolates, HN gene sequence of both isolates was aligned with sequences of NDV isolates previously published in GenBank. The resulted alignment was then analyzed in terms of phylogenetic relation and variation. phylogenetic analysis of the isolated virus showed that both Iraqi isolates share significant similarity with 14 other international stains. Two strains of India origin and 12 was China isolates. The identity percentage was 99% - 100% with clustered group. Interestingly, Iraqi isolate was different from the neighbor countries such as Iran, and other Middle East countries. These results may indicate that certain migratory birds might have contributed to the distribution of NDV in Iraq. However imported infected beards from south East Asia may contribute to the current NDV outbreaks caused by foreign strain.

دراسة جزيئية مصلية وكيميائية عن الاصابة بطفيلي انابلازما مارجينالي في الابقار في محافظة الكوت Some Molecular ,Sero - Prevalence And Biochemical Study of Anaplasma Marginale In Cattle In Al - Kut Province

اسم المؤلف: علا عبد الحسين عكار الكفاري
اسم المشرف: غيداء عباس جاسم الجبوري
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الطب البيطري
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: صممت الدراسة للبحث في انتشار مرض الانابلازموسسس بين قطعان الابقار في مناطق مختلفة من محافظة واسط وقد اجري البحث على 184 عينة دم جمعت من ابقارمشكوك في اصابتها تعاني من الحمى (°41c) , فقر دم شديد , شحوب الاغشية المخاطية ,هزال شديد وانخفاض في انتاج الحليب. و| The study was designed to investigate the prevalence of bovine anaplasmosis among cattle from various area in Wassit governorate , the investigation is performed on 184 blood samples collected from suspected cattle suffering from fever (41°C), severe anemia ,pale mucus membrane , progressive emaciation and drop in milk yield , includes (85) males and (99) females , aged < 1year to 2 - 3 years, during October 2012 to April 2013 from AL - Kut , AL - hayy , AL - Bashair , AL - Moufaqia and AL - Noamania areas to investigate antibodies against Anaplasma parasite by using indirect ELISA test and to determine the species Anaplasma marginale by using RFLP - PCR technique, also measuring some biochemical parameters to indicate the effect of the disease on liver function. Results of ELISA test showed that the rate of infection was 13.04 % , and there were different between age groups without significant difference were give 8 % , 11.25 % and 16.45 % in ages < 1year , 1 - 2 year and 2 - 3 years respectively. There was no significant differencerecorded between females that give study revealed that females were give 14.14 % rate of infection and males with 11.7 % rate of infection.The highest rate of infection was recorded in AL - Kut 17.14 % followed by AL - hayy and AL - Bashair were give 14 % ,10 % respectively and the lowest rate was recorded in AL - Noamania and AL - Moufaqia 8.33 % , 5% respectively, the study showed significant differences in incidence of disease between study districts and area in Wassit province under p > 0.05. The most sensitive method used for the diagnosis of anaplasmosis was polymerase chain reaction , DNA extraction was performed only on 24 blood samples which were positive for Anaplasma parasite by ELISA test, the extracted DNA from blood cells were analyzed by PCR and PCR - RFLP technique using primers derived from 16S rRNA gene and restriction endonuclease Bst1107I enzyme which recognized the sequence (GTATAC) in corresponding PCR product of A. marginale and cut it in the position 68, whereas the used restriction enzyme can not cut the corresponding PCR product of other Aanaplasma spp. and the result was 20 from 24 was positive for Aanaplasma spp. by PCR and 18 from 20 was positive for A. marginale. The results of liver enzymes activity showed significant increase in serum AST, ALT, CK and TBIL level in infected cattle (96.8±0.97), (42±0.52) , (406±2.06) and (0.95±0.24) respectively as compared with control (65.5±1.26 ), (21.4±0.45 ) ,( 142±14.17 ) and (0.27±0.05 ) respectively.

تشخيص وتوصيف جراثيم الاشريشيا القولونية والمكورات العنقودية الذهبية ذات الاحتمالية المرضية المعزولة من الحليب الخام للابل والجاموس بالطرق الاعتيادية والجزيئية Identification And Molecular Characterization of Potential Pathogenic Staphylococcus Aureus And Escherchia Coli Isolated From She - Camel And Buffalo Raw Milk

اسم المؤلف: اسراء تلفان عناد
اسم المشرف: باسل عبد الزهرة عباس بسام ياسين خضير
الموضوع العام: الطب البيطري
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: تم جمع 430 عينة ,215 عينة من حليب الجمال الخام جمعت من مناطق مختلفه من محافظة البصرة ومحافظات بالمنطقة الجنوبية للعراق و215عينة من حليب الجاموس الخام جمعت من مناطق مختلفة من محافظة البصرة خلال فترة ثمانية اشهر(اب 2012 - اذار 2013) حيث تم جمع الحليب يدويا | During a period of eight months (August 2012 to March 2013), a total of 430 samples were collected from 215 camel milk samples, 215 buffalo milk samples from different regions in Basrah city and other cites in southern area in Iraq. All specimens were screened for the presence of E. coli and S.aureus by cultured on MAC, EMB and MS agar media.A total of 51 (11.8 %) of suspected E. coli isolates were obtained; 23 (10.6%) from camel milk samples and 28 (13.0%) from buffalo milk samples. The study showed higher occurrence of E. coli in buffalo milk samples than camel milk samples. All suspected E. coli isolates were tested with Api 20 and 35(68.6%) were confirmed as E. coli. Staphylococcus aureus were also isolated as suspected staph, A total of 39 (9.06) were obtained; 17 (7.9) from camel milk samples and 22 (10.2) from buffalo milk samples. The study showed higher occurrence of S.aureus in buffalo milk samples followed by camel milk samples. After test the suspected staph with api test appear 27 (69.2) were confirmed as S.aureus.All the isolates of E.coli and S. aureus were tested to at least 12 antibiotics to which they were subjected. All the isolated bacteria (100%) of E. coli isolates were susceptible to gentamycin,imipenem and amikacin but resistant (100%) to amoxicillin, trimethoprim, azithromycin ,amoxicillin/clavulanic acid, cephalothin, cefixime and cefoxitin. Some of them (50%) were resistance to nalidixic acid. Three isolates 75% were resistance to tetracycline whereas 75% were susceptible to ciprofloxacin, and nitrofurantoin. Intermediate susceptibility to ciprofloxacin ,nalidaxic acid , nitrofurantoin and tetracyclin was observed among 25% of the E. coli isolates whereas 25% showed resistance to nalidixic acid. Therefore, all these isolates were considered to be multidrug resistant.E. coli were further examined by PCR technique using two pairs of primers to amplify both itsf and pai genes. The results revealed that all (85.7%) of the isolates were positive for itsf gene, 57.1% of isolates yielded amplification products with Pai - PCR gene. Staph aureus examined to presence of mecA gene by technique using pairs of primers and it was found that 51.8% of strain contain that gene. Clustalw multiple sequence alignment of icd gene of E.coli and arcC gene of S.aureus isolates and three previously reported E.coli and S.aureus was done.

دراسة تاثير مستخلص الشاي الاخضر مقارنة بالانسولين على بعض الصفات الفسلجية والتعبير الجيني في الارانب المستحدثة تجريبيا بالسكري Study The Effect of Green Tea Extract As Compared With Insulin On Some Physiological Parameters And Gene Expression In Experimentally Induced Diabetic Rabbits

اسم المؤلف: ماهر مهدي صالح العارضي
اسم المشرف: حيدر عبد الكاظم نغيش الزاملي
الموضوع العام: الطب البيطري
السنة: 2014
الموضوع الدقيق: الفسلجة
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: القادسية
الصفحات الاولى:
المستخلص: هدفت الدراسه الحاليه لتحديد التاثيرات المحتملة للمستخلص المائي للشاي الاخضر200 ملغم / كغم في اناث الارانب المستحدث فيها السكري تجريبيا. استخدام 35 انثى ارنب بالغة من النوع المحلي تراوحت اعمارها 6 - 10 اشهر معدل اوزانها 1 - 1،5 كغم. قسمت الى خمسة مجاميع مت | The present study aimed to determine the effect of aqueous extract of green tea (200 mg / kg B.W) in experimentally induced diabetic female rabbits.Thirty five female rabbits with arange age of 6 - 10 months and 1 - 1.5 kg weight were used.They are divided into five equal groups.The first group used as negative control (C),The diabetes melltitus (DM) was induced in T1,T2 and T3 by injection of single dose of alloxan 100 mg /kg B.W in marginal ear vein , The T1 assigned as positive control. The T2 treated with 200 mg / kg B.W of aqueous extract of green tea for 8 weeks.The T3 treated with 3 IU/ SC of insulin for 8 weeks while the T4 was given 200 mg / kg B.W of aqueous extract of green tea alone for 8 weeks. After 5 days of diabetes mellitus induction the blood samples were taken from the same vein, the rabbits which have blood glucose more than 200 mg / dl blood consider as diabetic. At the end of the experiment blood samples were taken by cardiac puncture and the blood serum was separated by Centrifuge to measure glucose , albumin, total protein ,liver enzymes and lipid profile and histological sections for pancrease,liver and kidney were done. the Real - time PCR was done to measure the gene expression of (Ins 1) and (Ins 2) which are responsible for insulin hormone production.the results were revealed that there is significant ( p <0.05) decrease in glucose,Low density lipoprotein,very Low density lipoprotein , Triglyceride , Total cholesterol , Alkaline phosphatase , Aspartate Transaminase and Alanine transaminase and significant increase (p <0.05) in Highy density lipoprotein , albumin and total protein in T2 group compared with T1, there is non significant differences in these parameters with T3 group , also there is significant decrease in ( p < 0.05) in Low density lipoprotein,Very Low density lipoprotein , Triglycerid , Total cholesterol and significant increase ( p < 0.05) in Highy density lipoprotein in T4 group compared with all groups. The gene expression results revealed that there is significant ( p < 0.05) increase in Ins 1 and Ins 2 gene expression in T2 compared with T1.The histological study of T1 was explain that there is severe congestion in pancrease with necrosis and absent of islets of langerhans while in the liver there is congestion with large thrombus in central vein with hepatic necrosis. In the kidney there is thrombus and congestion in renal tissue and destruction in renal tubules. While in T2 most damage caused by alloxan was disappeared through regeneration of cells of studied organs

دراسة تاثير مبيد البيرمثرين Permethrin على اجنة وفروج الدجاج Gallus domestics Study The Effect of Permethrin Insecticide In Chicks Embryos Gallus Domestics And Chicks After Hatching

اسم المؤلف: اسراء عبد الزهرة قوري المياحي
اسم المشرف: علاء عبد الخالق حسين مجدي فيصل مجيد العلي
الموضوع العام: الطب البيطري
السنة: 2011
الموضوع الدقيق: التشريح والانسجة والاجنة
الدرجة: ماجستير
الجامعة: جامعة البصرة
اللغة: العربية
مكان الجامعة: البصرة
الصفحات الاولى:
المستخلص: This study was carried out in the college of veterinary medicine / Basrah university to find out the toxic effect of the synthetic parathyroid insecticides (permethrin) in embryos kidney and young chick Gallus domestics ,eggs were obtained (227) from Baghdad poultry farm, weights were (55.23 - 69.50) g. The study divided in to two main parts : The first part used (50) eggs were injected with experimental doses (0.00033,0.00022,0.0004,0.0001,0.00005) mg/L of permethrin insecticide before incubation , the results revealed : - A positive correlation between embryonic mortality percentage and insecticide concentration were obtained , whereas the (LD50)values were decreased with increase of exposure time, and the lowest value was recorded at (0,00033) mg/l after (96) hr. of exposure time according to this results the following concentrations of (0.00033,0.00022)mg/l for permethrin were taken.The second part (177) eggs were divided into (9) groups according to the age : 4,7,9,11,14,16,18,19 and the final one included group with 7 day age after hatching.Eggs were injected before incubation with 0.00033, 0.00022 mg/L of insecticide in air sac, while the control group with distal water were injected.The results showed significant differences (p<0.05) in length for groups that injected with concentrations (0.00022,0.00033) mg/L compared with control group specially (19,28 day)of age; on the other hand there were a significant differences (p<0.05) between groups that injected with 0.00022mg/L compared the other groups(0.0003mg/L) in( 28 day).This study shown a significant differences (p<0.05)in weight between groups that injected with (0.00033,0.00022)mg/L in (19,28 days) compared with control group.Also the study shown a significant differences(p<0.05) in weight for groups that injected with (0.00033,0.00022)mg/L from 14 to 28 days compared with the first days and it were the same differences that occurred in control group with less significant differences.The teratological changes of embryos and young chicks according to age were studied in the nine ages which mention above; while the histopathological changes by permethrin studied for mesonephron and metanphron in the same aging groups.Teratological changes occurred according to the following : - opisthotonus in (4th day) ,decrease in epithelial pigment of eyes in (4th,7th days), incomplete development of limbs and wings in (7th,11th,14th,16th,19th days) and some embryos in (11th day) have abnormal growth in maxillary bones , longitudinal fissure dorsally and abnormal brain.Delay growth of feathers in( 9th,11th,14th,19th days ), growth of tail in (9th , 14th days), incomplete development of beak in (9th,11th,18th days) , abnormal growth of skin in (9th,14th,18th,19th days) , congestion in head in (9th ,11th days) , swelling in head and incomplete entering of yolk sac from body in (19th day).The embryos in (14th ,16th ,19th days) suffered from abnormality of the some organs which located out of the body uncompleted development of the vitelline circulation of yolk in (14th day) while the chicks suffered from paralysis of wings and limbs and ruffled feathers.The study results recorded some embryos cases which detected for the first time with the following signs : cleft in dorsum skin region continue from down of neck to lumbar region of embryo body (11) ages , negation growth pads in embryo(11,19) ages ,exit organs out sides the body called hernia in (14,16,19 days), negation retraction yolk sac in to body in last days of incubation( 19) ; finally negation keratinized skin and scales for limbs in( 18 )day of incubation.Histopathological changes were observed in the kidney sections fo both embryos and chicks that injected with (0.00022,0.00033)gm/l of permethrin , included glomeruli and tubular necrosis, swelling in endothelial layer of tubules, absent of glomeruli in some sections accompanied by infiltration of inflammatory cells, congestion in the glomeruli ,decrease in diameter lumen of tubules,absent of space of Bowman's capsule ,swelling diffused in kidney, enlargement of glomeruli ,absent of the histological structure characters of glomeruli and tubules ,enlargement of some tubules nuclei were detected in comparison with the control groups.

كفاءة التنظيف لمبرد XP - endo Finisher بالمقارنة مع انظمة الارواء بالتردد الصوتي والتردد فوق الصوتي : دراسة خارج الجسم Cleaning Efficiency of Xp - Endo Finisher File In Comparison With Sonic And Ultrasonic Irrigation Systems (An In Vitro Study)

اسم المؤلف: مهند غازي عزاوي
اسم المشرف: جمال عزيز مهدي
الموضوع العام: طب الاسنان
السنة: 2016
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: This in vitro study was conducted to evaluate and compare the efficiency of XP - endo Finisher, EndoActivator sonic irrigation system and the NSK Varios ultrasonic irrigation system in removing dentin debris at three levels of root canals and to compare the percentage of dentin debris among the three levels for each irrigation system. Sixty freshly extracted upper molar teeth with straight palatal root canals were used in this study. All canals were prepared with ProTaper NEXT rotary files to size X4, 1mm from the anatomic apex with irrigation of 1 ml 2.0% NaOCl between the files. After that the samples were randomly distributed into three groups of twenty samples each, irrigated with 1 ml 2.0% NaOCl, followed by irrigant activation for 60 seconds with three different irrigation systems; group one, by using the XP - endo Finisher; group two, by sonic irrigation using the EndoActivator system; and group three, by ultrasonic irrigation using the NSK Varios, then all the groups received a final rinse of 5 ml 2.0% NaOCl. After the final rinse, the roots were split longitudinally into two parts and photographed with a professional digital camera. The digital images were then transferred into a computer and opened in Adobe Photoshop CC 2015 software and the canal was magnified 200x. The percentage of dentin debris remaining at the apical level (0 - 3mm), the middle level (3 - 6mm) and the coronal level (6 - 9mm) was calculated by dividing the number of pixels occupied by the dentin debris at each level by the number of pixels representing the entire canal area. Data were analyzed statistically by ANOVA and LSD at 1% and 5% significant levels. This study showed that cleaning the canal with the XP - endo Finisher or NSK Varios ultrasonic irrigation system resulted in significantly cleaner canals (P<0.01) than the EndoActivator sonic activation system at all canal levels. The XP - endo Finisher resulted in cleaner canals than the NSK Varios ultrasonic irrigation system at all levels, but the difference is not statistically significant (P>0.05). The apical level of all the canals showed a greater amount of dentin debris (P<0.01) compared to the middle and coronal levels, regardless of the irrigation device used.

تحليل القوى المستقرة لثلاثة انواع مختلفة من المواد الراتنجية بطريقة عملية وعددية Static Stress Analysis For Three Different Types of Composite Materials Experimentally And Numerically

اسم المؤلف: محمد وائل سعيد
اسم المشرف: حكمت عبد الرحيم الغراوي
الموضوع العام: طب الاسنان
السنة: 2016
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: t is important to analyze and compare the stresses induced in different composite material types during load application to know which type of composite will behave as preferred under the loading in the same circumstances. This study aimed at measuring and comparing the stress induced in Filtek ™ Z350 XT (3M ESPE) composite, Tetric EvoCeram ® (ivoclar vivadent) composite and BRILLIANT ™ NG (Coltène/Whaledent) composite experimentally and numerically.Experimental analysis included cavity preparation in the Brass block with a concave (U - shape) cavity which represent a proximal cavity preparation. This cavity was used as a mold for sample preparation. The internal line and point angles of the cavity (mold) were rounded and the dimensions of the cavity (mold) were 10mm × 10mm × 10mm (Total height of the box × Width of the top side of box × Length of the top side of box). The internal diameter of “U” was 5 mm at the base of the box. The mold was used to prepare forty five samples, fifteen samples for each type of composite material. So, three groups were prepared : Group A filled with Filtek ™ Z350 XT composite material, Group B filled with Tetric EvoCeram ® composite material and Group C filled with BRILLIANT ™ NG composite material.Electrical strain gauge (Tokyo Sokki, Japan) was embedded in composite material horizontally at the same level in each sample. Static load of 50 N was applied perpendicular to the center of the occlusal surface of composite restoration in each sample testing. The strain gauge was connected to a Wheatstone bridge with a signal amplifier which measures the strain during load application and gives the amplified signal from (0 to 4.8 volt) to LabJack data acquisition where a stream software give the final values of strain with the aid of a scaled equation of voltage. Then, the von Mises stress (effective stress) was calculated by using equations. Numerical analysis was done by using ANSYS 16.1 - (2015) (finite element tool) software that was used to create the 3 - Dimensional models represented the same materials and dimensions used experimentally. The physical characteristics of the composite models were inserted in the software which included Elastic modulus and Poisson’s ratio (?). Analysis was selected in a finite element method according to boundary conditions. A mesh size and an element size were estimated during the study. The stresses were calculated at static load of 50 N with the ANSYS 16.1 - (2015) software.The data were analyzed statistically by One - way ANOVA test and Least Significant Difference (LSD) test. One - way ANOVA test and LSD test results showed that there was a highly significant difference (P<0.001) presented between groups A and B, groups A and C and between groups B and group C. The Stress induced in BRILLIANT ™ NG composite after load application was the lowest stress value followed by Tetric EvoCeram ® composite and followed by Filtek ™ Z350 XT composite which was the highest stress value experimentally and numerically.

التسرب المايكروي لنوعين من القشرة الخزفية بوجود وعدم وجود الحشوة الراتنجية تحت جهاز التحميل الدوري Microleakage of Two Porcelain Laminate Veneers Materials With And Without Composite Filling Under Cyclic Loading

اسم المؤلف: ياسر علي النقيب
اسم المشرف: عمار عطا الله علي السعدي
الموضوع العام: طب الاسنان
السنة: 2016
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Although investigators have evaluated the microleakage of porcelain laminate veneers, there is insufficient data regarding the durability of porcelain laminate veneers bonded to existing composite fillings. The aim of this study was to evaluate the microleakage of porcelain veneers restorations fabricated from two types of CAD/CAM ceramic blocks bonded to teeth with or without composite class V composite filling.Forty eight sound, crack - free human maxillary first premolar extracted for orthodontic reasons were selected for this study. Teeth were divided randomly into.2 main groups, which further divded into 2 groups (12 sample each). Group A1 : IPS e.max CAD veneers with standardized class V composite filling, Group A2 : IPS e.max CAD veneers, Group B1 : VITA Suprinity veneers with standardized class V composite filling, Group B2 VITA Suprinity veneers. The class V cavities was restored with nanofilled composite (Filtek™ Z350 XT, 3M ESPE). Standard veneer preparations were made using Ceramic veneer burs system (Keramikveneers. de, Komet). All the veneers were milled by CAD/CAM technology (CEREC MC XL, inLab SW 15, Sirona Dental Systems) Composite fillings (groups A1 and B1) were sandblasted with alumina oxide.Porcelain veneers were cemented in place using light - cured resin cement (Rely Veneer Cement, 3M ESPE), Then the specimens were stored at 37? in distilled water for 2 weeks. Then mechanical load cycling (50,000 load cycle of 49 N at 2.5 Hz) and thermocycling procedure (500 cycles of 5 - 55 Co with 20 sec dwell time) were done. The specimens’ crowns were immersed in 2% methylene blue dye for two days, then mounted in clear acrylic before sectioning with a 0.35 mm microtome. Microleakage percentage were recorded using stereomicroscope and ImageJ program. Results were checked for normality of distribution (Kolmogorov - Smirnov test and Shapiro - Wilk test), and were analyzed with twoway ANOVA and independent samples t - tests. Two way ANOVA shows the significant effect of type of ceramic restoration and the highly significant effect of composite filling, however, the interaction between the main factors was non - significant. The results showed that the lowest mean of microleakage percentage was recorded for group A2 (4.6058% ± 1.5091) which considered statistically significant compared to group B2 (6.105%±1.456), and statistically highly significant compared to group A1 (6.6075%±1.3259) while group B1 recorded the highest mean of microleakage percentage (7.3158%±1.38713). In conclusion, the type of ceramic restoration and the presence of class V filling both had significant effects on microleakage of porcelain veneers. IPS e.max CAD veneers had significantly lower microleakage percentages compared to VITA Suprinity veneers. The presence of class V composite filling within the cervical finishing line of porcelain veneers had a highly significant higher microleakage percentage compared to groups without composite filling.

احتمالية حدوث العيوب في عاج الجذر نتيجة لاستخدام انظمة مختلفة من مبارد النيكل تيتانيوم The Incidence of dentinal root defects caused by different Nickel Titanium instruments

اسم المؤلف: نور الدين علي سعيد
اسم المشرف: ايمان محمد الزقة
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: يعد الاعداد الميكانيكي الاحيائي لقنوات الجذر احد الخطوات الرئيسية لتحقيق حشوة جذر ناجحة بسبب امكانية ازالة الاجسام البكتيرية والحطام المتراكم وتسهيل وضع حشوة الجذر داخل القنوات. الغرض من هذه الدراسة هو لملاحظة ومقارنة احتمالية حدوث العيوب في عاج الجذر نتي | Vertical root fracture and crack formation can be seen in root dentin during and after endodontic procedures. Vertical root fracture is one of the most frustrating complications of root canal treatment, which often results in tooth extraction. The aim of this in vitro study was to compare the effect of different Nickel Titanium instruments (ProTaper Universal, EndoSequence, ProTaper Next and RECIPROC) on the dentinal wall in term of dentinal defects.Seventy - five straight palatal roots of freshly extracted human maxillary first molars teeth were used in this study, the palatal roots were sectioned at 11 mm from the apex and wrapped with two layers of aluminum foil, then placed in the center of elastic silicon mold. Fifteen roots were left unprepared to serve as a negative control group, the remaining 60 roots were divided into 4 groups, each group contained 15 roots : • Group I was prepared by rotary ProTaper Universal system.• Group II was prepared by rotary EndoSequence system.• Group III was prepared by rotary ProTaper Next system.• Group IV was prepared by reciprocating RECIPROC system.All canals were prepared to MAF # 40. After each file size of the (rotary files) or after three pecking motion of the (reciprocating files), the file was removed from the canal and the canal was irrigated with 1 ml of 2% of sodium hypochlorite. All files were cleaned periodically to prevent clogging of flutes during instrumentation. The canal remained patent by insertion size 15 K - file.When the instrumentation was completed, the roots were then embedded in a clear acrylic resin blocks and each root was sectioned into three levels : apical, middle and coronal. All samples were examined from coronal direction under Stereomicroscope. The number and the type of dentinal defects were recorded and classified. The collected data was tabulated and subjected to statistical analysis using chi - square test.The EndoSequence group showed the lowest number of dentinal defects followed by ProTaper Next group and then ProTaper Universal group. The highest number of dentinal defects were observed in RECIPROC group. Chi - square test showed that there were highly significant differences among groups (P < 0.01). The results showed a non - significant difference between EndoSequence and Protaper Next group (p > 0.05), and a significant difference with ProTaper Universal group (P < 0.05) and a highly significant difference with RECIPROC group (P < 0.01). The ProTaper Next group showed a significant difference with ProTaper Universal group and a highly significant difference with RECIPROC groups. There was no significant difference between RECIPROC and ProTaper Universal groups.

انسلاخ المبيضات اللعابي المقاس بواسطة تفاعل البوليميراز المتسلسل الكمي اللحظي كاداة تنبؤ لحصول التهاب المبيضات الفموي عند مرضى الربو المتعاطين لدواء بيكلوميتازون المستنشق Salivary Candidal Shed Measured By Real Time Quantitative Polymerase Chain Reaction As A Predictor of Oral Candidiasis In Asthmatic Patients On Inhaled Beclomethasone Dp Therapy

اسم المؤلف: نغم قطران رحيم
اسم المشرف: رعد محي الدين حلمي
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الربو القصبي المزمن يمثل مشكله صحيه جديه في كل العالم وهو عادة يبدا في عمر الطفوله ويبقى المريض في كثير من الاحيان يتعاطى العلاجات المستنشقه مدى الحياة.انتشار الربو القصبي يزداد في كثير من دول العالم مما يجعله احد الامراض المعيقه والمهدده للحياة باعتبا | Asthma is a serious global health problem that usually starts in childhood and continues along patient’s life and most of them have to take inhaled therapy lifelong. The prevalence of asthma is rising in many countries of the world, making asthma one of the most disabling and life threatening diseases effecting patients with different age groups and social classes with variable clinical spectrums and outcomes starting from mild to severe disabling syndrome rendering nonproductive individuals to severe life threatening and sometimes fatal disease. Those patients continue inhaled steroid therapy for long duration, considered by GINA as first line treatment , however such a treatment is associated with local adverse effects on oral tissues, and one of the main concerns is the development of oral candidiasis, a chronic, potentially invasive, infection of oral tissues with fungus candida species resulting in failure of treatment. The scientific interests about such a serious complication have been raised over the past years and debates continued as the candida is considered one of the normal flora of the oral cavity in most of healthy population, however oral candidiasis in pathogenic forms still occur in immunocompromised patients including asthmatics on inhaled corticosteroid therapy.Aim of the study1. To investigate the effect of inhaled corticosteroid therapy in form of Beclomethasone Dipropionate250 microgram/dose CFC free in asthmatic patients on salivary candidal shed estimating by Real Time quantitative Polymerase Chain Reaction (RT qPCR) applied on direct unstimulated saliva samples.2. Evaluation of this shed as prediction of occurrence of oral candidiasis. Patients, Materials and MethodsThis study was conducted at Al Zahraa consultational Asthma and Allergy center - Baghdad Al Karkh Health Directorate from September 2013 to February 2014.The included patients were divided into 3 groups. Group A included asthmatic patients on inhaled Beclomethasone therapy, group B included asthmatic patients that never used any form of inhaled steroid therapy and group C was those asthmatic patients on inhaled Beclomethasone therapy who developed oral candidiasis. All patients were receiving two daily doses. The same exclusion forma was applied to choose Group D who were control healthy individuals. Each included patients and control cases were instructed to give saliva samples in the standard way and samples taken for estimation of candidal count by real time quantitative Polymerase Chain Reaction.Results During the study period, 698 patients were examined, however only 63 patients were included in the study. Those 63 were classified as follows : 28 patients were found on group, 28 were found on group B and only 7 patients were found on group C and 20 cases were selected in group D as a control.Group C patients were having the highest salivary candidal shed (mean=58.7x106 cn/ml) and longest duration of asthma (Mean=2718 days) and longest duration of Beclomethasone therapy (Mean=2224 days) and this was significantly higher than other groups (p<0.05).Group A patients were having the second highest rank after group C in regard of salivary candidal shed and both duration of asthma and Beclomethasone therapy. Inside each group, duration of asthma and duration of Beclomethasone therapy were associated with moderate positive correlation with salivary candidal shed (R>0.5).Age difference between groups were insignificant and age factor had no correlation with salivary candidal shed inside the groups.Discussion : Salivary candidal shed over the groups was directly related to the duration of inhaled Beclomethasone therapy and duration of asthma. They are significantly higher (p<0.01) as we go further from each group to the next, both appear as the reason behind increased candidal shed in groups A and C.The salivary candidal shed curve will gave us a very useful tool for follow up those patients on inhaled steroid therapy ,In addition , predict the risk of developing oral candidiasis and when to interfere prior to the establishment of Oral Candidiasis state as that we have noticed in the group C, in which it was recommended to stop inhaled steroid therapy and the patients would lose the benefits of the therapy.Conclusions1. Resting saliva samples with realtime quantitative PCR was a rapid and accurate tool in diagnosis of oral candidiasis.2. Salivary Candidal Shed could be used as a tool in predicting oral candidiasis in asthmatic patients on inhaled Beclomethasone therapy.3.Longer duration of asthma and longer duration of Beclomethasone therapy were associated with increased salivary candidal shed and established oral candidiasis have the highest amount of shed.4. Candida albicans are present in the oral cavity of any individual of our population

تقيم التسريب الجزني لمركبات الراتنج للحشوات الخلفية سونك فل مركب مستند على السيلورين ومركب نانوفل مستند على الميتاكرليت في : دراسة مقارنة Microleakage Evaluation of Sonicfill

اسم المؤلف: مهند احمد الحداد
اسم المشرف: حكمت عبد الرحيم الغراوي
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Resin composites have improved greatly since their introduction and are now the materials of choice for most of the restorations. This study was conducted with aim of comparing in vitro the marginal adaptation of three different, low shrink, direct posterior composites Sonic fill™ (nanohybrid composite), Filtek™ P90 (Silorane - based composite) and Filtek™ Z350 (nanofill composite) of a standardized Class V cavity after thermoal cycling. Sixty sound, freshly extracted human premolars were prepared with standardized Class V cavities. The specimens were divided into three groups of twenty teeth each according to the material used : Group A : The teeth were restored with Sonic fill™ posterior composite unidose capsules, Group B : The teeth were restored with a silorane - based posterior composite (FiltekTM P90), Group C : The teeth were restored with nanofill methacrylate - based composite (Filtek™ Z350 XT).After specimens were stored in distilled water at 37°C for 7 days, all specimens were subjected to thermocycling at (5° to 55 °C), then immersed in 2% methylene blue dye for 24 hours. For each group microleakage at the occlusal and gingival regions was estimated by determining dye penetration using scoring system under steromicroscope (10X). The statistical analysis of the results showed that, Filtek™ P90 silorane based composite exhibited the lowest mean of microleakage, with statistically highly significant difference (P < 0.01) when compared with Sonicfill™ composite and Filtek™ Z350 XT nanofill composite. On the other hand, the results of this study showed that Sonic fill™ composite exhibited no significant difference (P > 0.05) as compared with Filtek™ Z350 XT nanofill composite. Also, the results in this study showed that there is a highly significant difference (P < 0.01) in dye penetration between occlusal and gingival regions for each group

تقييم اصابة المفصل الفكي الصدغي عند مرضى الصدفية باستعمال التصوير المقطعي المحوسب للكشف عن التغيرات المفصلية Evaluation of The Involvement of The Tempromandibular Joint In Patients With Psoriasis Using Computed Tomography For Detection of Psoriatic Arthritis Changes

اسم المؤلف: منتهى فوزي صالح
اسم المشرف: هاجر ابراهيم عبد الله
الموضوع العام: طب الاسنان
السنة: 2015
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: اضطرابات المفصل الفكي الصدغي تشير الى مصطلح مركب يحتوي على عدة حالات تتضمن المفصل الصدغي,التركيبات المحيطة او كلاهما.اضطرابات المفصل الفكي الصدغي هي مجموعة اعراض معقدة اكثر من كونها حالة معينة واحدة, ويعتقد انها تنتج من عدة عوامل مثل : العوامل الجينية, ال | Tempromandibular disorders is a collective term, embracing several clinical problems involving the muscles of mastication, temporomandibular joint (TMJ), or both.Tempromandibular disorders is a symptom complex rather than a single condition, and it is thought to be caused by multiple factors like : genetic, developmental and metabolic.TMDs form a cluster of related disorders with common symptoms which include localized pain, limited or asymmetric movement, and clicks or grating on opening.Psoriatic arthritis is a chronic inflammatory arthropathy that affects patients with psoriasis. Psoriatic arthritis is most commonly a seronegative oligoarthritis found in patients with psoriasis and therefore occurs more commonly in patients with tissue type HLA - B27. The clinical findings for Tempromandibular Psoriatic arthritis are pain, tenderness, limitation of movement , joint stiffness, clicking as the jaw is opened or closed, difficulty in opening the mouth, locking of the jaw,and crepitations. These findings are essentially the same as for Tempromandibular disorders.• Objective of the study : • To determine the extent of tempromandibular joint involvement in patients with psoriatic arthritis.• To correlate between clinical findings and radiographic finding.Materials and method : In this study 98 patients were selected ,50 male and 48 female, their age ranged between(18 - 68)years. They were collected at Al - yarmook teaching hospital/department of dermatology during the period from ( NOV 2014 - May 2015).They were diagnosed as having psoriatic arthritis by a dermatologist according to (Moll and Wright diagnostic criteria 1973).These patients were sent to rheumatoid factor test RF to exclude the presence of rheumatoid arthritic disease, then the patients were exposed to CT scanning for the Tempromandibular joint in Al - Yarmook teaching hospital for screening the involvement of TMJ with psoriatic arthritis by the presence of any radiographic changes such as erosion, flattening,osteophyte and sclerosis in the condylar head.Results : The result of the study showed that the mean age of psoriatic arthritic patients in TMJ was (44.2) years, and the female percentage was (48.4%) and the male was (51.6%). Psoriatic arthritis in TMJ showed high significance in the unilateral side symptoms (100%) it was significant in patients with positive family history (54.8%), and non significant in the right/left ratio (41.9%). Oligo type was found in twenty six patients (83.9%) with significant p - value. Clinically, all symptoms including clicking, tenderness and tempromadibular joint pain were highly significant, limitation showed (54.8%), TMJ pain showed (64.5%) and tenderness showed (54.8%).Radiologically : CT scan showed sensitivity for erosion in TMJ (54.8%), for osteophyte (32.3%), for condylar flattening (16.1%) and for sclerosis (9.7%) while specificity for all were (100%). Association between clinical symptoms and radiological changes showed non significant correlation. Conclusions : Psoriatic arthritis of TMJ has been found oftenly unilateral (oligo type). Female/ male ratio is about 1 : 1. nearly 50% of patients were having limitation in mouth opening. Most of the patients were having positive family history.The development of psoriatic arthritis in TMJ is related to the duration of the disease. Plaque psoriasis is the most associated type with the psoriatic arthritis in TMJ. Most of patients with psoriatic arthritis show psoriatic nail changes. The most radiographic findings found in patients with psoritic arthritis was erosion in the condylar head. There is association between clinical and radiologic findings for psoriatic arthritis in TMJ.

ضبط الحواف ومقاومة الكسر لاغلفة ال Ceramill Sintron المعدنية المصممة والمصنعة بالحاسوب مكسوة بثلاث انواع مختلفة من الخزف Marginal Discrepancy And Fracture Resistance of CAD\CAM Ceramill Sintron Metal Copings With Different Porcelain Materials

اسم المؤلف: مصطفى نبيل عبد الغني
اسم المشرف: عمار عطا الله علي السعدي
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: دقة الحواف والقوة، لاي ترميم معوض للاسنان هي صفة مهمة. ويمكن اعتبارعدم تطابق للحواف او قلة القوة سبب مهم يؤدي الى فشل التعويضات الاصطناعية للاسنان.لذلك تم اجراء هذا البحث لغرض تقييم اختلاف ظبط حافات ومقاومة الكسر لتيجان السيراميك المصنعة من اغلفة الC | Marginal fit and strength are important criteria for any restoration; poor marginal fit and low strength may be considered as a source of prosthesis failure. This study was performed to compare the marginal fit changes and facture resistance of metal ceramic crowns constructed from Ceramill Sintron metal coping veneered with three different porcelain veneering materials (Vita Master Koromikos VMK, Willi Geller Creation CC and GC initial MC). Also evaluating the influence of thermocycling on load at fracture value. The method included the use of master brass die which was milled to represent the prepared maxillary central incisor. Sixty metal copings were milled directly using Ceramill Sintron blank, then divided randomly into three groups. Each group consist of twenty metal copings, then veneered with porcelain : VITA for group A, Creation for group B and GC for group C. The marginal gap was measured before and after porcelain veneering for each group using travelling light microscope, then marginal fit changes was calculated. Fracture resistance test was done by Instron®, the master die was duplicated to sixty analogs then each analog was fixed into acrylic base. After that each crown was cemented onto the corresponding die analog using zinc phosphate cement. Ten samples of each group were subjected to compressive loading to fracture and other ten subjected to thermocycling followed by compressive loading to fracture.The result showed that GC group was highly significant different from other tested groups in marginal fit changes, whereas there was no significant different between VITA and Creation group. While there was significant difference among tested group at (P < 0.01) in fracture resistance, and the effect of thermocycling process did not significantly reduce the load at fracture for all groups.This study concluded that GC group present the least marginal fit changes, while the fracture resistance was highest for VITA group follow by Creation then GC. Thermocycling reduce load at fracture but not significantly.

A Comparative Study To Evaluate Canal Transportation And Centering Ratio At Different Levels of Simulated Curved Canals Prepared By Irace, Protaper NEXT And Protaper Universal Files A Comparative Study To Evaluate Canal Transportation And Centering Ratio At Different Levels of Simulated Curved Canals Prepared By Irace, Protaper NEXT And Protaper Universal Files

اسم المؤلف: محمد علي فاضل
اسم المشرف: Hikmet A. Sh. Al Gharrawi
الموضوع العام: طب الاسنان
السنة: 2015
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: تحضير قناة الجذر يشمل كلا من تشكيل وتوسيع المساحة اللبية بالاضافة الى تطهيرها من الجراثيم، من دون اي خطا اجرائي هو من اقصى درجات التفضيل. حديثا، في مجال تطبيقات حشوات الجذور، ادوات النيكل تيتانيوم اصبحت تستخدم بصورة شائعة لتنظيف وتشكيل قناة الجذر. ادوات ا | Root canal preparation includes both shaping and enlargement of the endodontic space in conjunction with its disinfection, without any procedural error is of the utmost preference. Recently, in endodontic practice, the nickel - titanium instruments are used commonly for the preparation of the root canal space. Nickel - titanium instruments are much more flexible than stainless steel files and have superior cutting efficiency. Super - elasticity of nickel - titanium rotary instruments allows the clinicians to produce the desirable tapered root canal form with a reduced tendency to canal transportation and instrument fracture. The target of this study was to measure and compare the canal transportation and centering ability of iRaCe and ProTaper NEXT nickel titanium instruments with ProTaper Universal instruments in simulated curved canals at different levels and compare canal transportation and centering ability among different levels for each tested instrument.Sixty simulated curved canals of 40°curvature were randomly divided into three groups of twenty canals each; the first group (group A) was prepared with iRaCe instruments, the second group (group B) was prepared with ProTaper NEXT instruments and the third group (group C) was prepared with ProTaper Universal instruments. The canals were prepared to an apical size 30 by crown - down instrumentation technique. Removal of material was measured at five different levels : at the canal orifice (O), half way to the orifice in the straight sections (HO); the beginning of the curve (BC); the crest of the curve (AC); the end point (EP). Pre - and post - operative photos of the simulated canals were taken in a standardized technique at magnification of 40X. An assessment of canals shape has been determined using Photoshop CC 2014 and AutoCAD 2014 software program. The data of canal transportation as well as centering ratio were analyzed statistically using Shapiro - Wilk, ANOVA and LSD tests.Within the limitation of this study, it is shown that canals preparation with the three designs of NiTi instruments produced canal transportation. However, the iRaCe instruments showed a significantly less canal transportation and a significantly better centering ability than both ProTaper NEXT and ProTaper Universal instruments at all levels of measurements, followed by ProTaper NEXT instruments that showed a significantly less canal transportation and significantly better centering ability at all levels when compared with ProTaper Universal, while the ProTaper Universal instruments showed the highest values of canal transportation and the worst ability to stay centered in the canals at all levels. Considering the direction of canal transportation, the iRaCe instruments showed minimal transportation towards inner aspect of canal at coronal and at the apex of curve and towards outer aspect of canal at middle, beginning of curve and at the end point of the preparation, while ProTaper NEXT instruments were showed transportation usually towards the inner aspect of the canal at middle part of the canal and towards the outer aspect at coronal, beginning of curve, apex of curve and at the endpoint of the preparation, while ProTaper Universal files were usually towards the inner aspect at middle part of the canal and towards the outer aspect at coronal, beginning of curve, apex of curve and at the endpoint of the preparation.

الانتشار والعلاقة بين اضطرابات المفصل الصدغي بين طلاب طب الاسنان على اساس معايير التشخيص والاجهاد والاضطرابات الفموية Prevalence And Correlations Between Temporomandibular Disorders In Dental Students Based On Diagnostic Criteria (DC/TMD) , Parafunctions And Psychoemotional Stress

اسم المؤلف: علا علي خلف
اسم المشرف: هاجر ابراهيم عبد الله
الموضوع العام: طب الاسنان
السنة: 2015
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: اضطرابات المفصل الصدغي والاضطرابات الفموية يبدو انها مشكلة متكررة في المجتمعات الحديثة. ويرتبط الباثولوجيا السببية المفصل الصدغي الى العضلات، واقواس الاسنان، ودواعم الاسنان. وتشمل الاسباب الرئيسية على حد سواء العوامل الفيزيولوجية المرضية والنفسية وا | Bagkground : The temporomandibular disorders (TMD) and oral parafunctions seem to be a frequent problem in modern societies. The etiopathology of the temporomandibular joints is related to muscles, teeth arches, and periodontium. Their main causes involve both pathophysiological and psychosocial factors. In the literature, a significant impact of the psychoemotional factor is reported, comparable to the impact of other factors concerning physical health such as systemic diseases, malocclusions, loss of teeth, and traumas. Stress, fatigue, anxiety, depression, sleep disorders, and a fast pace of life affect negatively the human psyche.Aim of study : The aim of the study was to assess the prevalence of temporomandibular disorders (TMD) and oral parafunctions, as well as their correlation with psychoemotional factors among dental students by using diagnostic criteria (DC/TMD).Subjects, materials and methods : the sample’s size of 407 students (169 males and 238 females) of dental college (100 fifth stage , 102 fourth stage ,99 third stage and 106 second stage ). Firstly students subjected for stress questionnaire (perceived stress scale - 10) , secondly they subjected to different clinical and questionnaire measures according to diagnostic criteria of temporomandibular disorders DC/TMD (axis1) which have standerized series of diagnostic tests based on clinical signs and symptoms , finally the dental students subjected for oral parafunctions questionnaire using oral behavior checklist.Results : the results obtained from this study showed that the prevalence of TMDs was significantly greater among students with oral parafunctions. We also observed that the prevalence of TMDs according to DC/TMD was higher among students with headache.In this study, the prevalence of psycho - emotional stress , TMD according to DC/TMD and oral parafunctions were higher in females than males and in fifth stage greater than other stages.Conclusion : • the prevalence of TMDs according to DC/TMD were significantly higher among females than males.• Oral parafunctions ( bruxism , cheek/lips biting , objects biting and nail biting ) showed greater prevalence in fifth stages than others and higher in females than males • In all stages females showed greater prevalence of psycho - emotional stress than males and among students of fifth stage the prevalence of psycho - emotional stress was higher than other stages.

قوة الدفع الرابطة الى الخارج والتسرب القمي للمواد (MTA Plus, Biodentine and Bioceramic) بتقنية حشوة ثلث القمي للجذر : دراسة مختبرية Push - Out Bond Strength And Apical Microleakage of (Mta Plus, Biodentine, And Bioceramic)As Apical Third Filling (An In Vitro Study)

اسم المؤلف: عبير علي عباس
اسم المشرف: جمال عزيز مهدي
الموضوع العام: طب الاسنان
السنة: 2015
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: اجريت هده الدراسة المختبرية لتقيم قدرة ختم لثلاث مواد استعملت ( بتقنة حشوة ثلث القمي لقناة الجذر ) باستعمال اختبار قوة الربط الدفع الى الخارج ودراسة التسرب القمي.ستين جذر حلقي الاسنان العلوية ذو قناة مستقيمة ذات فتحة قمية مكتملة التكوين مختارة بعناية وفق | This study was conducted to evaluate the sealing ability of three materials used as apical third filling by using push - out bond strength test and apical microleakage study.Sixty straight palatal roots of freshly extracted maxillary first molars were selected. All teeth had mature apices, selected carefully according to specific criteria. The roots were instrumented using crown down technique with rotary Protaper universal system, instrumentation were done with 5ml of 2.5% sodium hypochlorite used as irrigation between files, 17% buffered solution of EDTA was used as final irrigant followed by 2.5% sodium hypochlorite then 10ml distilled water to remove any remnant of irrigant. Roots were randomly divided into three groups according to the filling materials used ( twenty roots for each group) : Group (1) : MTA Plus ( 4mm thickness) using as apical third filling. Group (2) : Biodentine (4mm thickness) using as apical third filling.Group (3) : Bioceramic root repair material (4mm thickness) using as apical third filling.Easy and Quick (E&Q) obturation system were used to complete obturation of roots. After incubation period at 37 °C for three days. Ten roots from each group were used for push - out test, after root were embedded in clear acrylic resin, sectioned at apical level in 2mm and 4mm from root apex to provide slice 2mm in thickness. The bond strength was measured using computerized universal testing machine, each section fixed in the machine so that the load applied from apical to coronal direction at 0.5mm/min speed and the computer drew curve to show the higher bond force before dislodgment of the filling material. These force were divided by surface area to obtain the bond strength in MPa.After debonding each sample was examined under Stereomicroscope and the type of failure mode was recorded. The result showed non significant different between Biodentine group and MTA Plus group. Biodentine group showed a very high significant difference with Bioceramic material group. Also high significant difference between MTA Plus group and Bioceramic material group. The Biodentine group showed highest mean of bond strength in comparison to other test group.Ten roots remain from each group used for apical microleakage study. The roots submerged in 2% methylene blue for three days. The roots were cleared and the degree of linear dye penetration was measured in millimeter by stereomicroscope under 40 X magnification with calibrated scale ocular grid. The result showed the Biodentine group lowest mean of microleakage than other group while Bioceramic material group showed high mean of microleakage than other groups. There are no significant difference among groups. There is positive correlation between push - out bond strength and an apical dye penetration in microleakage for each group of material.

فشل القشور الخزفية المصنوعه من السيراميك باستخدام تقنيات اللصق المختلفة : دراسة مقارنة مختبرية Failures of Porcelain Laminate Veneers Using Different Techniques of Bonding (A Comparative In Vitro Study)

اسم المؤلف: صفا عدنان كعيد
اسم المشرف: عمار عطا الله علي السعدي
الموضوع العام: طب الاسنان
السنة: 2015
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Esthetic dentistry as a concept and adhesive materials development as a functional element make the new dawn of dentistry especially with the continuous development of adhesive techniques. This study is to evaluate the failure patterns of porcelain laminate veneers used to esthetically restore maxillary first premolar by bonding them to enamel and dentin with two different techniques.Forty eight extracted human maxillary first premolar were used for this study. Teeth were divided randomly into one control group and three experimental groups of twelve teeth eachGroup (A) were prepared in enamel (0.5 mm) depth of preparation. Group (B) were prepared in dentin (1 mm) depth of preparation and their veneers were bonded by DDS technique. Group (C) were prepared in dentin (1 mm) depth of preparation and their veneers were bonded by IDS technique. Standard preparation for each tooth in the experimental groups with ceramic veneer set burs especially designed for laminate veneer preparation. All the experimental groups were restored with the same type of veneer which was lithium disilicate ceramic CAD/CAM blocks (IPS e. max CAD, ivoclar vivadent) and were milled by CAD/CAM technology (CEREC inLab 4.02 milling system, Sirona).For all the experimental groups, Choice™2 veneer cement (Bisco, USA) was used for the luting of veneers. After cementation, teeth were stored in distilled water in 37°C for one week. The specimens were loaded to failure using instron universal testing machine. Specimens in experimental groups were examined by stereomicroscope at magnification of 20x to evaluate the mode of failure.Results were statistically analyzed and showed that the highest mean of failure load was recorded for the control group (548.1 N ± 93.2), for group (A) the mean of failure load was (393.4 N ± 84.2), and for Group (B) had the mean of failureAbstract IIIload was (237.8 N ± 91.6), and for group (C) the mean of failure load was (318 N ± 82.2).The one way ANOVA test was carried out and showed that there is a statistically high significant difference among the groups.Then the LSD test have shown that there is a statistically high significant difference between the control group and all three of the experimental groups, and there was a statistical high significant difference between group (A) and group (B), while group (C) have shown that there is a statistical significant difference with groups (A) and (B).The mode of failure varied from only debonding in groups (B and C) to deboning and fracture in group A.In conclusion, this study found that although enamel is still the most favorable tooth substrate for indirect adhesive restorations, the development of bonding techniques like IDS made dentin as acceptable tooth substrate for indirect adhesive restorations when it's unavoidable.

تقييم صحة الفم والبروتينات اللعابية لدى المرضى المصابين بمرض باركنسن Assessment of The Oral Health And Saliva Proteins In Patients With Parkinsons Disease

اسم المؤلف: صباح فرحان مشتت
اسم المشرف: هاجر ابراهيم عبد الله مروان صالح النمر
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Parkinson's disease (PD) is a progressive neurodegenerative disorder related to the loss or absence of dopaminergic neurons in the brain. The deficits caused by PD result in slowness of movement, tremor, rigidity, and dysfunction of behavior and these symptoms negatively influence the patient’s capability to carry out the daily oral hygiene manoeuvres.Aims of study : This study aims at using saliva as a biological fluid for assessment in detecting the biomarkers of Parkinson's disease and to assess the impact of this disease on the oral health of patients.Materials and methods : A total number of fourty participants were involved in the study; twenty subjects who appeared healthy (Group I) and twenty Parkinson's patients (Group II). Patients who are eligible for this study were cases of Parkinson's disease treated with anti - Parkinson's medications, both genders and their ages ranged from 40 - 75 years. Specific information related to the demographic characteristics and illness is obtained from each patient. The Brain Bank Diagnostic Criteria for Parkinson’s disease established by United Kingdom Parkinson's Disease Society was used. Each patient was subjected to oral examination during which DMF index was scored, oral health impact Profile OHIP - 14 was used and from each participant the whole unstimulated saliva was collected for biochemical analysis including total salivary protein, direct determination of saliva proteins and determination of ? - synuclein. Results : many oral and clinical signs and symptoms elsewhere in the body were reported in the patient with Parkinson's disease while the clinical features of Parkinson's disease observed in all patients despite of their treatment. Static tremor observed in 100%, rigidity in 70%, disturbances in the autonomic nervous system reflected on the cardiovascular, gastrointestinal and urinary tracts, orthostatic dizziness observed in 75%, dry mouth in 65% difficulties in swallowing in 40% and constipation in 70%. Teeth examination revealed that Parkinson's patients have a non - significant high means of decay and missing teeth compared with healthy subjects. The total saliva protein in Parkinson's patients is significantly higher than the corresponding value of healthy subjects. The extinction coefficient of uncontaminated protein in Parkinson's patients is significantly less than the corresponding values of healthy subjects and salivary ? - synuclein level is significantly less in Parkinson's patients than healthy subjects.Conclusions : Salivary ? - synuclein may serves as a biomarker for Parkinson's disease. Specific protein with extinction coefficient 27.5 M.Cm - 1 is secreted in saliva of Parkinson's patients. The characteristic saliva protein produced in patients with Parkinson's disease is deficient in tyrosine level and Dental care is required for both groups (Parkinson's patients and healthy subjects).

الاستريتين الفموي مقابل غلوكونات الزنك عن طريق الفم : دراسة علاجية مقارنة وعبورية في علاج مرض بهجت Oral Acitretin Versus Oral Zinc Gluconate As A Comparative Cross - Over Therapeutic Study In Treatment of Behcet,S Disease

اسم المؤلف: سناء عبد الحميد حسين
اسم المشرف: هاجر ابراهيم عبد الله عادل عبد الغفور النعيمي
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: اساس البحث : مرض بهجت هو اضطراب جهازي حيث ان اسبابه المرضيه ليست محدده جيده.المظاهر الاكثر شيوعا هي الاغشيه المخاطيه الجلديه ولكن يمكن ان يشمل العين, انظمة القلب,الاوعيه الدمويه والجهاز العصبي. هناك العديد من طرائق المعالجه الموضعيه والجهازيه. تمت محاول | Background : Behcet’s disease is a systemic disorder where its etiopathogenesis is not well determined. The commonest manifestations are muccocutaneous but can involve eye, cardiovascular and neurological systems. There are many modalities of therapy topical and systemic.Isotretinion has been tried as an effective therapy of muccocutaneous manifestations. In present work was to try a new retinoid like acitretin which has longer half life than isotretinoin.Aims of the study : To evaluate the effectiveness of oral acitretin versus oral zinc gluconate in the treatment and prophylaxis of Behcet’s disease as a new therapeutic model.Materials and methods : This cross over controlled therapeutic study that conducted in the Department of Dermatology - Baghdad Teaching Hospital the period from August 2013 - May 2014.Twenty patients with fulfilled criteria of Behcets’s disease was included in this work. History and full examination were done for all patients regarding all demo - garaphic points related to the disease. They were given acitretin 25 mg orally once daily for three months to be seen on the day fourteenth firstly and then monthly to be assessed depending on the clinical manifestation index for Behcets disease. After three months, acitretin was stopped and patients were given zinc gluconate 25 mg twice daily for another three months. Results : Twenty patients were treated 12 males (60%), and 8 females (40%), with male to female ratio 1.5 : 1. All these patients completed the study and their ages ranged between 20 - 59 years with mean± SD (37.3±12.3). Pathergy both ordinary and oral were also minimized by this therapy while C - reactive protein was not much effective by this therapy. Zinc gluconate also had the same therapeutic action against these manifestations. Clinical manifestations index before treatment ranged between 1 and 11 with mean ± SD of 5.65±1.98.After acitretin therapy the mean of CMI started to decline to reach 2.65 ±2.03 in first month of the therapy with (p=0.00001) which was statistically high significant and continued high significant till the end of the third month with (p - value > 0.000001). After cessation of acitretin and zinc gluconate started the mean continued to decrease to reach 2.05±2.52 at the end of the first month with (p=<0.000001) which was statistically high significant then; started to increase to reach 3.3 ±2.31 at the end of six month of the therapy but statistically remained high significant (p - value=0.0007). Both acitretin and zinc gluconate have statistically significant effect in reducing severity and frequency of oral ulcers, genital ulcers, skin and rheumatologic manifestations. Conclusions : oral acitretin was found to be an effective therapy in addition to its prophylactic action in treatment of muccocutaneous manifestations of Behcet,s disease. Also zinc gluconate had effective therapeutic action against these features of Behcet’s disease.

تاثــير مستوى الاسترادايول والبروجستيرون في اللعاب على حالة صحة الفم عند النساء اثناء الحمل Effects of Salivary Level of Estradiol And Progesterone On Oral Health Status In Women During Pregnancy

اسم المؤلف: زينة كامل كاظم
اسم المشرف: هاجر ابراهيم عبد الله
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الحمل هو حالة فسيولوجية تجلب مجموعة واسعة من التغييرات في حياة المراة، بما في ذلك التعرض لامراض اللثة، ربما بسبب التغيرات الهرمونية المرتبطة مع الحمل. قد تؤثر الهرمونات الجنسية على اغشية الفم واللثة وربما هذا يؤدي الى العديد من الامراض اللثوية. ان هرمونا | Pregnancy is a physiological state that brings a wide range of changes in a woman’s life, including a susceptibility to gingival disease, probably due to hormonal changes associated with pregnancy. These female sex hormones may modify the oral mucosa and may lead to various degrees of gingival inflammation. The hormonal changes occurring during pregnancy may be associated with pregnancy gingivitis and gingival bleeding. Sex hormones are specific regulatory molecules have long been considered to play an influential role on periodontal tissues especially gingiva, bone turnover rate, wound healing and periodontal disease progression. Aims of the study1. Assessment of oral hygiene level and dental status in both second and third trimester pregnant women and compares results.2. Assessment salivary hormonal levels of endogenous female sex steroids in both second and third trimester pregnant women and compares results.3. Comparison of oral health status and endogenous female sex steroids salivary hormonal levels between gingivitis and non - gingivitis subgroups of both second and third trimester pregnant women groups.4. Find out the association between the gingival health status and salivary hormonal levels of endogenous female sex steroids (Estradiol and progesterone).Materials and methods This study was carried out on seventy - eight pregnant women who were attended for routine and regular follow up visits in obstetrics and gynecology department at Al - Yarmouk Teaching Hospital, from February 2013 to July 2013. This study was approved by the scientific committee in the department of oral medicine college of dentistry Al - Mustansiriya University. They were divided according to gestational age in to second trimester group and third trimester group. Fifty pregnant women (age range 18 - 38 years) and at gestational age was ranged between (20 - 27 weeks) were recruited as 2nd trimester group and Twenty - eight pregnant women (age range 18 - 39 years) at gestational age ranged between (28 - 33 weeks) were recruited as 3rd trimester group and according to Loe and Silness gingival index these two groups subdivided into gingivitis and non - gingivitis groups. Oral clinical examination including an assessment of gingival inflammation (Loe and Silness Gingival Index), Plaque amount (Silness and Loe Plaque Index), dental status (Decayed Missing Filling Teeth), and salivary flow rate (SFR) had also been done. Samples of whole unstimulated (resting) saliva were collected from all participants then investigated for sex steroids salivary hormonal levels of Estradiol, Progesterone. Results and discussion Oral health measurements including : GI, PLI, SFR and DMFT showed no significant difference between 2nd trimester and 3rd trimester groups. Sex steroids salivary hormonal levels of Progesterone showed a significant difference with higher mean value in 3rd trimester pregnant women than 2nd trimester pregnant women while sex steroids salivary hormonal levels of Estradiol showed no significant difference between two groups. Comparisons between gingivitis and non - gingivitis subgroups of 2nd trimester pregnant women group showed that there was highly significant difference in SFR with higher mean value in non - gingivitis group, and there was highly significant difference in PLI with higher mean value in gingivitis group, DMFT showed non - significant difference between the subgroups and (Estradiol and progesterone) salivary hormonal levels showed highly significant difference with higher mean values in gingivitis group. Comparisons between gingivitis and non - gingivitis subgroups of 3rd trimester pregnant women group showed that there was a non - significant difference in SFR, DMFT and a highly significant difference in PLI with higher mean value in gingivitis group, while progesterone salivary hormonal levels showed non - significant difference and Estradiol salivary hormonal levels showed a highly significant difference with higher mean value in gingivitis group. Comparison of GI between gingivitis groups of both 2nd and 3rd trimester pregnant women showed that there was a significant difference with higher mean value in 3rd trimester. Estradiol and progesterone salivary hormonal levels were non - significantly correlated with PLI and GI for gingivitis and non - gingivitis group of 2nd trimester pregnant women. Progesterone salivary hormonal level was non - significantly correlated with PLI and GI for gingivitis and non - gingivitis group of 3rd trimester pregnant women while Estradiol salivary hormonal level was non - significantly correlated with PLI and GI for non - gingivitis group and significantly correlated with PLI and GI for gingivitis group. GI and PLI for gingivitis groups of both 2nd and 3rd trimester revealed that there was a highly significant correlation.Conclusions Female Sex steroids hormones (Estradiol and Progesterone) salivary hormonal levels significantly increase from the second to the third trimester especially Estradiol and Play an important role in influencing gingival inflammation during pregnancy. These hormones are neither necessary nor sufficient to produce gingival changes by themselves. However, they may alter periodontal tissue responses to microbial plaque and thus indirectly contribute to gingivitis. Dental status in pregnant women is not significantly different between 2nd and 3rd trimester pregnant women groups. Women should be offered training in good oral hygiene habits, and community awareness programs should be conducted to increase their awareness of the crucial importance of such habits especially during pregnancy

قياس قوة الدفع للخارج لحشوات الجذور GuttaFlow 2 , Thermafil وGuttaCore : دراسة مختبرية Push Out Bond Strength of Guttaflow 2, Thermafil, And Guttacore Obturation Materials (An In Vitro Study)

اسم المؤلف: حيدر طالب فاضل
اسم المشرف: جمال عزيز مهدي
الموضوع العام: طب الاسنان
السنة: 2015
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: اجريت هذه الدراسه المختبرية لقياس قوة ارتباط لثلاثه مواد مختلفة لحشوات قنوات الجذور باستخدام قوة الدفع للخارج.ثلاثون جذر حلقي مستقيم من الاسنان العلوية الخلفية استخدمت في هذه الدراسه وهذه الاسنان تم تحضيرها بتقنيه التاج السفلي باستخدام نظام المبارد الد | This in vitro study was carried out to investigate the push out bond strength of three different obturation materials GuttaFlow 2, Thermafil and GuttaCore at different levels.Thirty extracted upper molars were collected and the platal roots were sectioned at the CEJ of the tooth. The platal roots were instrumented with Hyflex CM rotary files to the size of 40/0.06.The instrumented samples were divided into three groups of ten samples each, the first group were obturated with GuttaFlow 2, the second group were obturated with Thermafil and the third group were obturated with GuttaCore obturating materials.After an incubation period of 7 days, each sample were sectioned into three sections of 2 mm thickness (apical, middle, coronal), each slice then introduced to the push out testing using a universal testing machine at a cross head speed of 0.5 mm/min. The result of this study showed Push - out bond strengths were significantly higher when canals were filled with GuttaCore than those filled with Thermafil and GuttaFlow 2. And Thermafil showed a higher significant difference than the GuttaFlow 2. It also showed that the bond strength values decreased from the coronal to the apical direction.In conclusion, the thermoplasticized gutta - percha appears to achieve higher push out bond strength values than the cold flowable gutta - percha. With GuttaCore showed higher push out bond values than Thermafil.

التاثيرات الدوائية لمادة - كاپا كراجينان - في مهنية طب الاسنان : دراسات داخل وخارج الانبوب The Pharmacological Effects of Kappa Carrageenan In Dental Practice : An In Vitro And In Vivo Studies

اسم المؤلف: اسيل جاسم علي
اسم المشرف: هاجر ابراهيم عبد الله مروان صالح النمر
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: كاراجينان هومركب يحتوي على پولي كلايكان الكبريتي وهو مستخلص من الطحلب الاحمر. الكراجين بطبيعته الغروية المائية يمتلك خواص هلامية,مثخنة ومستحلبة تسمح باستخدامه بكثرة في الصناعات الغذائية,مستحضرات الصحة الفموية والكماليات.وبسبب مركباته الحياتية الفعالة فقد

Evaluation of the Involvement of the Tempromandibular Joint in Patients with Osteoarthritis and the Accuracy of Ultrasonography as Compared to Computed tomography for Detection of Osteoarthritic Changes.

اسم المؤلف: احمد عادل عثمان
اسم المشرف: هاجر ابراهيم عبد الله
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: خلفية البحث : اضطرابات المفصل الفكي الصدغي تشير الى مصطلح مركب يحتوي على عدة حالات تتضمن المفصل الصدغي ,التركيبات المحيطة او كلاهما , تظهر على شكل الم في منطقة المفصل والعضلات المرتبطة,وتحدد بالقدرة على الحركة الطبيعية مثل المضغ, الكلام والبلع. مرض التهاب | Tempromandibular joint disorders is a collective term embracing a number of conditions affecting the TMJ, the surrounding structures or both,manifested by pain in the area of joint and associated muscles, and limitation in the ability to make normal movement like mastication,speech and swallowing. Osteoarthritis is a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. A variety of causes—hereditary, developmental, metabolic, and mechanical deficits may initiate processes leading to loss of cartilage. When bone surfaces become less well protected by cartilage, bone may be exposed and damaged. As a result of decreased movement secondary to pain, regional muscles may undergo atrophy, and ligaments may become more lax.Objective of the study : • To determine the extent of tempromandibular joint involvement in patients with osteoarthritis.• To evaluate the correlation between clinical and radiographical findings. • To evaluate the accuracy of sonography in detection of osteoarthritic changes compared to Computed tomography.Materials and method : A comparative study had been done using thirty six symptomatic patients(24 female and 12 male) above 40 years diagnosed as osteoarthritis by specialist rheumatologist in Alkarkh general hospital, with clinical finding related to osteoarthritis like pain,tenderness,crepitation, clicking and limited mouth opening. these patients were exposed to computed tomography(CT) scan (Philips - Brilliance 64) in Al - Karkh general hospital and then the results were compared with sonographic findings (Philips 12.5 MHz transducer) to see the disc displacement, effusion, erosion, flattening, osteolytic and osteophytic lesions in the condylar head.The period of the study started from (october - 2013 to june - 2014).Results : The result of the study showed that the mean age of osteoarthritic patients was (49.69) years, and female percentage (66.7%) and male(33.3%). Chief complaine showed more predilection in the left side (28%) and bilateral showed(56%).Clinically : limitation in mouth opening (50%),crepitation(36.11%), clicking (27.7%), and tenderness (20.8%). Radiographically Computed tomography(CT) scan showed disc displacement (50%), joint effusion (37.5%), flattening(36.11%), osteophyte(18,05%), and erosion(11.1%). There was significant correlation between clicking and joint effusion in computed tomography(CT),while tenderness showed significant correlation with osteophyte and joint effusion in sonography. Other correlations were non significant correlation between clinical and radiological changes. Association between computed tomography(CT) and sonography showed fair agreement in osteophyte detection,fair agreement in joint effusion,moderate agreement in detection of joint erosion,moderate agreement in reduction of space and anterior disc displacement and also moderate agreement in condylar head flattening. Conclusions : Osteoarthritis in tempromandibular joint may be unilateral or bilateral. About 50% of Patients with osteoarthritis have limitation in mouth opening. Clinical findings play a major role in diagnosis of osteoarthritis. The tempromandibular joint changes in osteoarthritis were the results of degenerative processes, in contrast to rheumatoid arthritis were the changes as a result of the disease. Sonography was more likely to be sensitive rather than specific in detection of osteoarthritic changes

حدوث وشدة الالم بعد استخدام ثلاثة انظمة مختلفة لتحضير قنوات الجذور Incidence And Severity of Pain Following The Usage of Three Different Root Canal Instrumentation Systems

اسم المؤلف: احمد حمد عبيد
اسم المشرف: جمال عزيز مهدي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: معالجة الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Postoperative pain after endodontic procedures is an undesirable occurrence for both patients and clinicians. Certain factors may predispose to the development of postoperative pain. Knowledge of the causes and mechanisms behind interappointment pain in endodontics is of utmost importance for the clinician to properly prevent or manage this undesirable condition. The causative factors of interappointment pain encompass mechanical, chemical, and microbial injuries to the pulp or periradicular tissues, which are induced or exacerbated during root canal treatment. Ninety patients were recruited and included in this study out of one hundred and twenty patients, those patients requiring endodontic treatment on their permanent upper or lower molar teeth with asymptomatic irreversible pulpitis preoperatively, access opening and instrumentation was performed at the same visit.Patients ranged in age from 19 to 50 years old, and all were in good health, as determined from a written health history and oral interview.The patients were assigned randomly into three groups of 30 patients each : ? First group (n=30) : Teeth were instrumented using Universal ProTaper System (Full Rotary technique).? Second group (n=30) : Teeth were instrumented using ProTaper Next System (Full Rotary technique).? Third group (n=30) : Teeth were instrumented using WaveOne System (Reciprocating technique).Pain assessment carried out at day 1, 2, 3 & 7 using Verbal Rating Scale (4 - Point Scale). Patients recorded the incidence and severity of pain experienced.Patients were called at 24, 48 and 72 hours to obtain their reports for the first three days. Seven days after treatment their records were reviewed and percussion test was performed. Result showed that all groups induced Post - operative Pain, the difference is some systems cause more Post - Operative pain than other do : group 3 (WaveOne group) showed higher incidence and severity of PostoperativePain, followed by group 1 (Universal ProTaper group) that has shown less incidence and severity of Post - operative Pain than group 3 (WaveOne group), last group which it was group 2 (ProTaper Next group) has shown the lowest incidence and severity of Post - operative Pain. The data obtained were analyzed statistically using Chi Square test, total score for Verbal Rating Scale at day 1, 2, 3, and 7 showed that there was a highly significant differences between ProTaper Next group and other twogroups (P ? 0.001), and non - significant differences between ProTaper group and WaveOne group (P ? 0.05).

تقدير الظواهر الفمويه والعوامل المناعيه في اللعاب عند مرضى سرطان الغدد اللمفاويه قبل وبعد العلاج الكيميائي Assessment of Oral Manifestations And Salivary Immunological Markers In Patients With Lymphoma Before And After Receiving Chemotherapy

اسم المؤلف: محمد حسن عبد الشهید
اسم المشرف: فواز داوود الاسود
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Lymphomas are group of diseases caused by malignant lymphocytes that accumulate in lymph nodes and caused the characteristics lymphadenopathy.Occasionally, they may spill over into blood or infiltrate organs outside the lymphoid tissue The major subdivision of lymphomas is into Hodgkin's lymphoma and non - Hodgkin's lymphoma and this is based on the histologicpresence of Reed - Sternberg cells in Hodgkin's lymphoma. Aims of the study : The aims of this study were to determine the percentage of oral manifestations and identify the levels of salivary immunoglobulin A, interluekin - 6 and tumor necrosis factor - ? in lymphoma patients before the treatment and after receiving three cycles of chemotherapy in comparison with healthy control individuals.Subjects, materials and methods : The study included 25 patients( 15 male and 10 female ) with non - Hodgkin's lymphoma (B - cell type), 25 patients( 16 male and 9 female ) with Hodgkin's lymphoma and 25 ( 15 male and 10 female ) healthy control group with no signs and symptoms of any systemic disease and age, sex match with patient groups.Those patients were examined pre and post chemotherapy to see the oral manifestations and compared with healthy control group. Whole unstimulated saliva was collected to determine the level of salivaryimmunological markers which measured by Enzyme Link Immunosorbent Assay.IVResults : The percentage of oral manifestations was taste alteration in non - Hodgkin's lymphoma patients ( 36% ) and in Hodgkin's lymphoma patients ( 16% ) , followed by burning mouth syndrome ( 20% ) in non - Hodgkin's lymphoma patients and ( 16% ) in Hodgkin's lymphoma patients and lastly dry mouth was ( 12% ) in both non - Hodgkin's lymphoma and Hodgkin's lymphoma groups. In the present study there was no oral manifestations in both study groups before starting chemotherapy, and the mentioned oral manifestations incident after receiving chemotherapy regimens. The levels of salivary immunoglobulin A, interluekin - 6 and tumor necrosis factor - ? were significantly higher in pre - treatment patients in comparison with control group, and there was a significant decrease after chemotherapy treatment when compared to their base line levels in both study groups.Conclusions : The most frequent oral manifestations in lymphoma patients was taste alteration followed by burning mouth syndrome and dry mouth , and male patients affected more than females.The salivary immunological markers levels were higher in lymphomapatients than control, then these markers showed obvious decrease in patients after chemotherapy treatment

تاثير مستخلصات الشاي الاخضر على مسببات امراض انسجة الاسنان الرابطة (بكتريا البورفايروموناس اللثوية وبكتريا اجريجاتيباكتر اكتينومايستيمكومتانس) : دراسة مختبرية Antibacterial Effects of Green Tea Extracts On Periodontal Pathogens (Aggregatibacter Ctinomycetemcomitans And Porphyromonas Gingivalis) (In Vitro Study)

اسم المؤلف: ميس جمال مجيد
اسم المشرف: سيف سهام سليم
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: امراض ما حول الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: المقدمة : الشاي الاخضرهو واحد من المشروبات العلاجية القديمة والشعبية المستهلكة في جميع انحاء العالم، وهو مشتق من ورقة للنبات "كاميليا سينينسيس", يمكن ان يحضر كمشروب، والذي يمكن ان يكون له العديد من الاثار الصحية الشاملة او "مستخلص" يمكن الحصول عليه من الاو | Background : Green Tea is one of the most ancient and popular therapeutic beverages consumed around the world, it is made from the leaf of the plant “Camellia sinensis”. It can be prepared as a drink, which can have many systemic health effects or an “extract” which can be made from the leaves to be used as medicine. Green tea is reported to contain thousands of bioactive ingredients including catechins, catechins found in the tea have shown promise for having antimicrobial effects.Aim of study : to test the effect of green tea extracts on Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in comparison to 0.2% chlorohexidine gluconate and distilled water in vitro.Materials and Methods : plaque samples were collected from 20 patients with no signs of any systemic disease suffering from chronic periodontitis with probing pocket depth of at least 6 mm, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans were isolated and diagnosed according to morphological characteristic and biochemical test. Green tea leaves were extracted by using water and alcohol. This study involved two experiments in vitro concerning the effects of green tea extracts on these bacteria in addition to analysis of the extracts to determine the concentrations of the catechins in each extract. The first experiments involved testing the sensitivity of A.a and P.g to different concentrations of the extracts in addition to chlorhexidine gluconate 0.2% and distilled water using agar well diffusion method, the second experiment involved determination of the minimum inhibitory concentration of the extracts that inhibits the bacterial growth and then determination of the minimum bactericidal concentration of the extract that was requires to kill the bacteria. The present study also involved laboratory analysis of green tea extracts using high performance liquid chromatography (HPLC).Results : Both green tea extracts were effective in inhibition of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans using agar well diffusion method, 90% and 100% concentrations of alcoholic extract showed larger inhibition zones than chlorhexidine gluconate 0.2% with statistically significant difference, CHX showed higher inhibition zones than all aqueous extract concentrations.The MIC (minimum inhibitory concentration) of alcoholic green tea extract that inhibit Aggregatibacter actinomycetemcomitans growth was 60% and it was the same for Porphyromonous gingivalis.The MIC of aqueous green tea extract that inhibits Aggregatibacter actinomycetemcomitans growth was 70% and MIC of aqueous green tea extract extract that inhibits Porphyromonous gingivalis was 80%.The MBC (minimum bactericidal concentration) of alcoholic green tea extract that kills Aggregatibacter actinomycetemcomitans was 80%, the MBC of alcoholic green tea extract that kills Porphyromonous gingivalis was 90%, the MBC of aqueous green tea extract that kills Aggregatibacter actinomycetemcomitans growth was 90%, which was also the same for Porphyromonous gingivalis.HPLC analysis of aqueous and alcoholic green tea extracts that were used in this study revealed that alcoholic extract contained higher concentration of EGCG while aqueous extract had higher content of catechin and epicatechin.Conclusion : green tea extracts were effective against Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, alcoholic green tea extract showed inhibition ability more than the aqueous green tea extract and more than chlorhexidine gluconate and it showed bactericidal activity at 80%, 90% and 100% concentrations.

الطريقة السريرية للتنبؤ بكثافة العظام السخية في المنطقة الواقعة بين الضاحك الثاني والطاحن الاول في البالغين العراقيين اصحاب الاطباق الطبيعي Clinical Method For Prediction of Alveolar Bone Mineral Density In The Area Between The 2Nd Premolar And 1St Molar In Iraqi Adults With Class I Occlusion

اسم المؤلف: مها علي حسن الجبوري
اسم المشرف: هديل علي حسين الهاشمي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Orthodontic mini - implants are increasingly used in orthodontics and the bone density is a very important factor in stabilization and success of mini - implant.The aim of this study was to observe the relationship among maximum bite force; body mass index; face width, height; masseter muscle length, width and thickness; and bone density in an attempt to predict bone density from these variables to eliminate the need for CT scan which have a hazard on patient.Computed tomographic images were obtained for 70 patients (24 males and 46 females) with age range 18 - 30 years. The cortical and cancellous bone density was measured between maxillary and mandibular 2nd premolar and 1st molar at two levels from the alveolar crest (3 and 6 mm). Face height and width and masseter muscle length, width and thickness were measured from CT. Clinically; Maximum bite force was measured on first molar region unilaterally by a digital device. The sample was divided into two groups according to the body mass index into; normal and overweight.The results that were obtained showed that there were no significant differences in bone density or maximum bite force in both genders. Only the cortical bone density in maxilla in overweight group tended to be higher than normal body mass index group. The face width and height correlated significantly negatively with or maximum bite force which correlated significantly positively with cortical bone density and masseter muscle width.It was concluded that a prediction of cortical bone density of preselected areas can be made from maximum bite force, body mass index and inter - zygomatic width

التقييم النسيجي والميكانيكي للتكامل العظمي لزرعات التتانيوم بعد تحرير تصميم الجزء المسنن من الزراعة او طلائها بمادة بذور الكتان : دراسة تجريبية على الارانب Histological And Mechanical Evaluation of The Osseointegration of Titanium Implants By The Modification of Thread Design And/Or Coating With Flaxseed (An Experimental Study On Rabbits)

اسم المؤلف: مصطفى هادي جواد
اسم المشرف: عذراء يحيى الحجازي نبيل كاظم عبد الصاحب
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: الانسجة الفموية
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Dental implant surface technologies have been evolving rapidly to enhance a more rapid bone formation on their surface and hold a potential to increase the predictability of expedited implant therapy.Numerous surface modification approaches have been developed for all classes of dental implants to modulate biological responses and improve the osseointegration and primary stability. Hence, Implant threads should be designed to maximize the delivery of optimal favorable stresses while minimizing the amount of extreme adverse stresses to the bone implant interface. In addition, using of biomaterial coating of implant surface for the enhancement of bone formation has been achieved through the modulation of osteoblasts adhesion and spreading that induced better stability and more implant surface contact area.The aims of the study are : 1. Evaluation of titanium implant osseointegration by the modification of thread design and I or coating its surface by Flaxseed.2. Evaluate the new surface modification of titanium implant, histologically, mechanically and radiographically.Materials and methods : One hundred and twenty eight commercially pure titanium (CpTi) screws were implanted in rabbit tibiae. Implants were divided as follows : 1. Dual - threaded group (32 implants). 2. Single - threaded coated with grinded flaxseed group (32 implants).3. Single - threaded with central groove (32 implants).4. Single - threaded (control) group (32 implants).Histological, mechanical and radiographical analysis were performed for all implants after each healing periods (2,4,6 and 8) weeks.Results : 1. Dual - threaded implant illustrated the highest mean value in thread width and removal torque, and it showed mature bone at 8 weeks.2. Grooved implant illustrated close opposing threads. 3. Coated implant illustrated highest mean value in osteoblast cell count and showed a proliferating cartilage zone that later on degenerated and replaced by bone.Conclusion : The present results conclude that each modified implants shows a different benefits whether a modification of the implant surface mechanically (dual or grooved thread) or by coating the implants with Flaxseed.

الظهور الكيميائي النسيجي المناعي للاوستيوكالسين، OC عاملا لنمو المحول بيتا واحد TGF - B1 وبروتين الشكل العظمي سبعة BMP - 7 في خلل التنسج الليفي والورم الليفي المعظم في عظام الفك : دراسة مقارنة Immunohistochemicalexpression of Osteocalcin, Transforming Growth Factor Beta - 1And Bone Morphogenetic Protein - 7 In Fibrous Dysplasia And Ossifying Fibroma of The Jaw Bones Acomparative Study

اسم المؤلف: فرح غسان ابراهیم
الموضوع العام: طب الاسنان
السنة: 2014
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Fibrous Dysplasia & Ossifying Fibroma of the jawsare maxillofacial fibroosseous lesions sharing anoverlapping clinicopathological characteristics. This can be diagnostically challenging for pathologists& surgeons. It is important to make the distinction because of differences in their clinical behavior, modes of treatment and prognosis.Osteocalcin is an immunohistochemicalmarker; secreted by osteoblasts and its high serum levelsare correlated with increased bone mineraldensity. It is therefore, used as biomarker for boneformation process and also has a role in regulationof osteoblast function.Transforming growth factor beta - 1 is a multifunctional regulator of cell growth which will either stimulate or inhibit proliferation of mesenchymal cells depending on the presence of other growth factors. It is secreted by osteoblasts and is very abundant in bone matrix. Bone morphogenetic protein - 7is a member of transforming growth factor - b superfamily; it is widely expressed during embryonic growth, and is an essential morphogen in renal, skeletal, and eye development.Aims of the study : This study aimedto evaluate and compare the Immunohistochemical expression ofosteocalcin, transforming growth factor beta - 1 andbone morphogenetic protein - 7in the pathogenesis of Fibrous dysplasia and Ossifying fibroma of the jaw bones,correlate the expression of the aforementioned markers in these lesions.Analyze theimmunohistochemical expression ofosteocalcin, Transforming growth factor beta - 1 & bone morphogenetic protein - 7 inFibrous dysplasia & Ossifying fibroma, in order to assess its potential role in differentiation between these two disease entities.Materials&Methods : A total of 30 retrospective formalin - fixed, paraffin - embedded tissue blocks were included in this study, 15 were diagnosed asFibrous dysplasia of the jaws and 15 were ofOssifying fibroma of the jaws. Animmunohistochemicalstaining method using ofosteocalcin,transforming growthfactor beta - 1 andbone morphogenetic protein - 7 monoclonal antibodies were performed.Results : The results revealed that the majority of cases (73.33%) were females for each Fibrous dysplasia &Ossifying fibroma. the age range was (8 - 35)years for Fibrous dysplasia and (7 - 50)years forOssifying fibroma. For Fibrous dysplasia most cases presented in maxilla (66.76%) while for Ossifying fibroma most of the cases presented in mandible (73.33), with more predominant Fibrous dysplasia cases in molar area (60%) and more presented Ossifying fibroma cases in premolar & molar area (33.33%). Statistically significant difference was found between Fibrous dysplasia&Ossifying fibroma cases regarding jaws & site distribution (P=0.02&0.04) respectively.Osteocalcin positive immunohistochemicalexpression was found in fibroblast - like cells in 4 cases(26.66%) of Fibrous dysplasia and in 7 cases (46.67%) of Ossifying fibroma, according to Chi - square test the result showed statistically significant difference regarding osteocalcin expression in Fibrous dysplasia &Ossifying fibroma (P=0.04). Transforming growth factor beta - 1 was positivelyexpressed in 8cases (53.3%) of Fibrous dysplasiaand 10 cases (66.67%) of Ossifying fibroma. Bone morphogenetic protein - 7showed positive expression in 2 cases (13.3%) of Fibrous dysplasia and 4 cases (26.7%) ofossifying fibroma.Statistically non - significant difference regarding the immunohistochemicalexpression of transforming growth factor beta - 1 and bone morphogenetic protein - 7in Fibrous dysplasia &Ossifying fibroma. Moreover significant correlation was found regardingtransforming growth factor beta - 1 expression in response to bone morphogenetic protein - 7in Fibrous dysplasia (P=0.03)and osteocalcin expression in response totransforming growth factor beta - 1 in Ossifying fibroma (P=0.01).Conclusions : Transforming growth factor beta - 1 expressin the majority of Fibrous dysplasia &Ossifying fibroma cases indicate its important role in the process of osteogenesis. The significant correlation seen regarding the expression of some of the studied markers with each other suggest their cooperative role in the pathogenesis of Fibrous dysplasia &Ossifying fibroma

الظواهر الفمية، مؤشرات عامل الغلوبولين المناعي اللعابي A، الانترلوكين واحد بيتا وعامل تنخر الورم الفا في لعاب مرضى - الكلى المزمن الخاضعين للغسل الكلوي في محافظة ميسان Oral Findings, Salivary IgA, Interlukin - 1 Beta And Tumor Necrosis Factor Alpha Markers In Saliva of Chronic Kidney Disease Patients Undergoing Hemodialysis In Missan Governorate

اسم المؤلف: فارس عبد حاتم
اسم المشرف: زاهدة جاسم محمد
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Chronic kidney disease refers to an irreversible deterioration in renal function which classically develops over a period of years, the ageing of populations along with the growing prevalence of chronic diseases such as diabetes and hypertension is leading to worldwide increase in the number of chronic kidney disease patients, the patients suffering from chronic renal failure face oral health related problems because it affects the bone and soft tissue structures.During hemodialysis, blood contact with a foreign surface, such as a complement - activating dialytic membrane, promotes a variety of complex and interrelated events, leading to an acute inflammatory response.Cytokines are a broad and loose category of small proteins that are important in cell signaling, they are released by cells and affect the behavior of other cells, they are important in health and disease, specifically in host responses to infection, immune responses, inflammation, trauma, sepsis, cancer and reproduction.Aims of study : The aims of this study was to determine the prevalence of oral findings, salivary flow rate and evaluation of salivary immunoglobulin A, interleukin - 1? and tumor necrosis factor ? levels in chronic kidney disease patients on hemodialysis treatment in comparison with healthy control, and investigate if there is a relation between these salivary parameters (salivary flow rate, salivary immunoglobulin A, interleukin - 1? and tumor necrosis factor ? levels) in chronic kidney disease patients on hemodialysis (less and more than one year) and finally find the correlation between salivary parameters in patients group.Methods : Ninety (90) subjects were participated in this study, they were divided into two groups : Patients group comprised of 45 subjects undergoing hemodialysis with chronic kidney diseases; Control group comprised of 45 subjects with no history of any systemic diseases.Intra oral examination was done for each individual to record the prevalence of oral findings in chronic kidney diseases patients. Saliva collected was measured and levels of salivary immunoglobulin A, interleukin - 1? and tumor necrosis factor ? were measured by enzyme linked immunosorbent assay (Elisa).Results : The most frequent oral findings in chronic kidney disease patients on hemodialysis, in this study were dry mouth (77.7%), uremic breath (bad odor) (55.5%) , taste alteration (55.5%), angular chelitis (35.5%), mucosal pallor (26.6%), burning mouth syndrome (28.8%), staining of teeth (26.6%), oral ulceration (11.1%) and petechia and ecchymosis (2.2%), and the present study showed that no statistically significant differences (p>0.05) were found in oral findings distribution except angular chelitis which showed statistically significant difference (p<0.05) between chronic kidney diseases patients on hemodialysis for less than one year & for more than one year. According to salivary flow rate, the present study found that there was a significant difference in patients with chronic kidney disease in comparison to healthy control subjects, also statistically there was no significant difference in salivary parameters (salivary immunoglobulin A, interleukin - 1? and tumor necrosis factor ? and salivary flow rate) in chronic kidney diseases patients on hemodialysis for less than one year & for more than one year. The present study showed that there was no correlation between salivary parameters (salivary immunoglobulin A, interleukin - 1? and tumor necrosis factor ? and salivary flow rate) except salivary immunoglobulin A and interleukin - 1? showed positive significant linear correlation (r=0.368, p=0.006) and negative significant linear correlation between salivary immunoglobulin A and salivary flow rate (r= - 0.275, p=0.009).Conclusions : Cytokines may play roles in pathogenesis of chronic kidney diseases represented by increasing interleukin - 1? and tumor necrosis factor ? levels in saliva of those patients, the chronic kidney diseases patients on hemodialysis recommended comprehensive professional oral care and self - care instructions

العلامات الالتهابية اللعابية وعلاقتها بحالة الفم الصحية بين مجموعة من الصبيان الذين يعانون من السمنة بعمر 21 سنة Salivary Inflammatory Biomarkers In Relation To Oral Health Status Among Obese Boys Aged 12 Years

اسم المؤلف: عاتكة رسول عزيز
اسم المشرف: احلام طه محمد
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان الوقائي
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Worldwide, obesity trends are causing serious public health concerns and significantly increases the risk of morbidity and mortality. It has an effect on the person`s general health including the oral health. Aims of the study : This study was designed to investigate the oral health status among a group of obese boys in relation to salivary inflammatory biomarkers (interleukin - 6 and Creactive protein) and selected salivary elements.Materials and methods : The study group consists of forty obese boy of an age 12 year, and forty normal weighted boy of the same age as a control group. Assessment of nutritional status was done by using Body Mass Index specific for age and gender. Dental caries severity was recorded by using the index of Muhlemann (1976). Plaque index of Silness and Loe (1964) was used for plaque assessment, calculus component of periodontal disease index of Ramfjord (1959) was used for calculus assessment and gingival condition assessed according to gingival index of Loe and Silness (1963). Unstimulated salivary samples were collected under standardized condition, salivary flow rate was determined and then the salivary samples chemically analyzed to determine the concentration of salivary interleukine - 6, Creactive protein, calcium, magnesium and phosphorus.Results : Caries experience of permanent dentition (DMFS) among study group was lower than that among control group with significant difference (P<0.05) for D2, while caries experience of primary dentition (dmfs) was significantly (P<0.05) lower among study group compared with control group with significant difference (P<0.05) for ds and highly significant difference (P<0.01) for d4.Salivary flow rate was lower among study group compared with control group with no significant difference. No significant correlations (P>0.05) were recorded between salivary flow rate and dental caries, oral cleanliness and gingivalhealth conditions among both groups. The mean value of plaque, calculus and gingival indices were not significantly lower among study group compared with control group. A positive highly significant correlations (P<0.01) were recorded between gingival and plaqueindices among both groups. The level of salivary interleukin - 6 (pg/ml) was higher among study group compared with control group with no significant difference between them; whereas there was no significant difference between the two groups regarding C - reactive protein (?g/ml) level. Salivary calcium and magnesium levels (mg/dl) were highly significantly (P<0.01) lower among study group compared with control group, whereas salivary phosphorus level (mg/dl) was not significantly higher among study group compared with control group. Salivary interleukin - 6 and C - reactive protein were negatively correlated with dental caries of both dentitions among study group with significant correlation (P<0.05) between IL - 6 and D2, while they were correlated positively with dental caries of both dentitions among control group with highly significant correlation (P<0.01) between IL - 6 and D3 and significant correlation (P<0.05) between IL - 6 and d4. Salivary calcium was correlated positively highly significantly (P<0.01) withDMFS and significantly (P<0.05) with D4 among control group. Salivary magnesium was correlated positively significantly (P<0.05) with DMFS and D2 among study group; also it was correlated negatively highly significantly (P<0.01) with d3 amongcontrol group. Salivary phosphorus was correlated significantly (P<0.05) in positive direction with d3 among study group; also it was correlated highly significantly (P<0.01) in negative direction with DMFS and significantly (P<0.05) in positivedirection with d3 among control group.

اثر التطبيق الموضعي من الكركمين مسحوق وزيت اساسي على التئام جروح الجلد : دراسة نسيجية وكيميائية نسيجية مناعية في الارانب Evaluation The Effect of Topical Application of Curcumin Powder And Essential Oil On Skin Wound Healing In Rabbits (Histological And Immunohistochemical Study On IGF - 1R)

اسم المؤلف: نضال حسين محمد
اسم المشرف: بان عبد الغني جميل
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: الانسجة الفموية
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: خلفية الموضوع : طب الاعشاب يمكن ان يعرف كواحد من فروع الطب باشكال مختلفة. وقد اثبت كركمين الكركم فعاليته كماده ملونة، ومنكهة واستخدم تقليديا في الطب،فقد اظهر له خصائص ملحوظه مضادة للالتهابا ت، مضادات الاكسده وخصائص بيولوجية متنوعة.ان عدم وجود سمية للكركم | Back ground : Herbal medicine can be called one of the branches of medicines in various forms.Turmeric curcumin has proved it's efficiencies a coloring, flavoring agent and has been traditionally used in medicine, exhibiting remarkable anti - inflammatory, and antioxidant properties. The varied biological properties of curcumin and lack of toxicity even when administered at higher doses makes it attractive toexplore its use in various disorders like diseases of skin.It is good potential agent for wound healing.Considerable interest has been focused on curcumin compound, mechanisms that drive wound repair are complex and have challenged wound - healing investigators for many years.Aims of the study : To evaluate the effects of topical application of curcumin (powder and essential oil)on skin wound healing histologically and immunhistochemically.Materials and methods : Sixty four New Zealand rabbits were used in this study, they were divided into four groups (16 animals for each healing period)each group was subdivided as follows : - Experimental groups(8 rabbits)subdivided into : a - Right facial side of(eight rabbits animal) for essential oil application Left facial side of(eight rabbits animal)for curcumin powder application - Control group (eight rabbits)(right facial sides used as control). Histological evaluation of wound healing was performed for all studied groups.Imunohistochemical analysis was utilized to localize and characterizethe IGF - R1 immuno positive cells at the wound site of allgroups (experimental and control).Results : Histological findings of the present study have shown that reepithelialization, wound contraction were accelerated after topical application of curcumin and essential oil. The results ofimmunohistochemical examination of this study revealed that there was increased expression of IGF - 1R by epithelial and connective tissue cells of skin especially with the topical application of curcumin oil at wound site.Conclusion : - Essential oil is more effective in enhancement of wound healing regarding histological and immuonohistochemical assessment revealed higher mean values of positive expression for insulin growth factor1receptor(IGF - 1R) , (for both stromal and epidermal).

دراسة نسيجية , شكليه نسيجيه ونسيجية مناعية للاستخدام الموضعي ل VEGF / Collagen I في تجويف الاسنان المقلوعة : دراسة تجريبية على الجرذان Histological, Histomorphometrical And Immunohistochemical Evaluation of Local Application of Collagen I And /Or Vascular Endothelial Growth Factor (An Experimental Study In Rats

اسم المؤلف: رفل راشد عبد السادة
اسم المشرف: عذراء يحيى الحجازي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: امراض ما حول الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Back ground : Healing socket consists of three new tissue components; epithelium, connective tissue, and bone tissue. Interactive dynamic changes take place between these 3 components during healing period.During the process of healing of the extraction socket the following events occur : firstly, a blood clot (mainly blood cells and network of fibrin) forms and fills the empty socket. Then, the blood clot matures and is organized by the formation of granulation tissue (rich in newly formed vascular structure, abundance of inflammatory cells. The granulation tissue replaces the blood clot completely by the seventh day. After 20 days, the granulation tissue was replaced by collagen, and bone began forming at the base and the periphery of the extraction socket. Epithelium covers the newly formed bone that filled the socket.The healing cascade of all wounds ultimately requires neovascularization, collagen deposition, and collagen constriction by myofibroblasts. Neovascularization in the adult is known to occur by two distinct processes, angiogenesis and vasculogenesis which needs for expression of VEGF.Aim of the study : Histological ,Histomorphometrical and immunohistochemical studies to evaluate the effect of local application of exogenous VEGF/collagen I separately and as a combination in socket healing.Materials and Method : Sixty male Albino Wistar rats were subjected for a surgical tooth extraction of upper 1st molar of both sides ( right side was considered as experimental site ,while left be the control one).The animals were divided into following groups according to the applicable of biomaterials.A. Control group the tooth socket treated with 1?L of normal salineB. Experimental group includes• Group I contains (20) rats, the tooth socket treated with 1?L of VEGF• Group II contains (20) rats the tooth socket treated with 1?L ofcollagen type I• Group III contains (20) rats, the tooth socket treated with 1?L of a combination of VEGF and collagen I. Each group is composed of 20 rats that will be studied in four periods 3,7,14,28 days (5 rats for each period).The specimens were studied histologically histomorphometrical and immunohistochemical identification of fibroblast growth factor 2 (FGF2) and tissue non specific alkaline phosphtase (ALP).Results : 1. Histological findings for all groups illustrate formation of blood clot at 3 days.2. Granulation tissue appears in all groups at 7 days period, and new bone is demonstrated in collagen group and a highly cellular woven bone with active proliferative osteoblast and newly blood vessel is detected in combination group.3. At 14 days new epithelization and new bone trabeculae with fibrous tissue are presented mostly in all groups but with different constitution.4. At 28 days all groups show reepithelization but in different thickness, and with newly bone apposition and with different maturity.5. For positive cells expressed ALP VEGF group records a high mean values at 3,14,28 days periods and with high differences in comparisum to other groups while control group reports a high mean value at 7 days.6. For positive cells expressed FGF2.Control group illustrates a high record for the mean of positive cells expressed FGF2 at 3,7days periods and with high differences in comparisum to other groups, while combination group reports a high mean value at 14 days.7. Results demonstrated that in most periods for each group ,whenever ,ALP is a high value in expression ,records a low expression in FGF2.Conclusion : Results ,high lighted on the effect of local application of VEGF in extracted tooth socket that facilited epithelization ,while combination of (Collagen and VEGF ) shows a high mineralization zone.

تقييم الظهور النسيجي الكيميائي المناعي لفايروسات (EBV,HPV16 - 18,HSV1) في الحزاز المنبسط الفموي Assessment of The Immunohistochemical Expression of Epstein - Barr , Human Papilloma (18 ,16) And Herpes Simplex - 1 Viruses In Oral Lichen Planus

اسم المؤلف: تانیه عبد الاله الطحان
اسم المشرف: احلام حمید مجید
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: امراض ما حول الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: يعد مرض الحزاز المسطح الفموي من الامراض الشائعة ولة مسار مرضي مرتبط بالخلايا المناعية ويرتبط باختلالات الاداء المناعي للجسم مع بعض الفرضيات التي تربط وقوع المرض بالعدوى الفايروسية. وھو من عائلة الھربس الفايروسية، بوقوع بعض الامراض ك "كثرة الوحيدات، EBV ار | oral lichen planus (OLP) is a common chronic inflammatory immune - mediated disease, The antigen responsible for inducing OLP is still unidentified, although viral agents have been proposed as etiologic factors. Viral infection (Epestin - barr,human papilloma and herpes simplex) has been hypothesized as a predisposing factor in the pathogenesis of this disease.Aims of study : The aim of this study was to assess the expression of Epstein Barr virus , Human Papilloma virus 16& 18 and Herpes Simplex virus - 1 immunohistochemistry in oral lichen planus cases and evaluate whether any clinical variant, histopathological or demographic feature correlates with the expression of these viruses.Materials and Methods : This study was performed on thirty formalin fixed, paraffin - embedded tissue Blocks of oral lichen planus retrospectively. An immunohistochemical staining done by using monoclonal antibodies EBV and HPV 18&16 and polyclonal antibody HSV1. Results : Expression of EBV was highly detected in epithelium of oral lichen planus cases (46.6%), no statistically significant correlation was found with clinical parameters.Astatistically significant with sex was observed.Immunostaning results revealed negative expression for both HPV16 & HPV18 in the studied cases except one case which was positive for each viruses. No statistically correlation was found with clinical parameters. Herpes simplex virus - 1 expression was positive in 12 cases (40%) of oral lichen planus cases. Statistically barely significant correlation with sex and clinical types, and a non significant one wasfound with age.ConclusionEpstein Barr and Herpes simplex viruses are present in considerable amounts in oral lichen planus whereas Human papilloma viruses 16 and 18 are rarely present.Taking into account the potential of viruses in OLP.

المؤشر الورمي CA153 عناصر مختارة في اللعاب وعلاقتها بصحة الفم والاسنان ضمن مجموعة من النساء العراقيات المصابات بسرطان الثدي Salivary Tumor Marker CA15 - 3 And Selected Elements In Relation To Oral Health Status Among A Group of Iraqi Breast Cancer Women

اسم المؤلف: بسمة عبد الباري عزیز
اسم المشرف: احلام طه محمد
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Breast cancer is the commonest type of malignancy worldwide and in Iraq. It is a serious disease that affects the general health and cause systemic changes that affect the physical and chemical properties of saliva leading to adverse effects on oral health.Aims of the study : The aims of this study were to assess the oral health condition (including dental caries, oral cleanliness and periodontal health condition), to evaluate the changes in salivary flow rate and to assess the concentration of tumor marker CA15 - 3 and selected elements (calcium, phosphorus, zinc, copper, total proteins) in saliva and their relation to oral variables among breast cancer women in comparison to control group.Subjects, Materials and Methods : The total sample consisted of 60 women aged 35 - 45 years attending Al - Kadhemyia Teaching Hospital. Those comprised 30 women newly diagnosed with breast cancer before starting treatment and 30 women without clinical signs and symptoms of breast cancer as a control group.Diagnosis and recording o f dental caries was done by using DMFS indexaccording to the criteria of WHO (1987). Plaque index of Silness and Loe (1964) and calculus component of Ramfjod index for periodontal disease (1959) were applied to assess oral cleanliness. Periodontal disease was evaluated using the gingival index (Loe and Silness, 1963) and loss of attachment level (Ramfjord, 1959). Stimulated salivary samples were collected and salivary flow rate, salivary CA15 - 3, calcium, phosphorus, zinc, copper ions and total proteins were determined.Results : Results showed that caries experience (DMFS) was higher among the study group compared with the control group but the difference was statistically not significant. The mean values of plaque index, calculus index, gingival index and loss of attachment were higher among the study group than the control group with a highly significant difference (P<0.01).The salivary levels of CA15 - 3 in breast cancer patients were higher than that of the controls with a highly significant difference (P<0.01). All the correlations between salivary CA15 - 3 and dental caries and periodontal diseases were statistically not significant.The salivary flow rate was lower among the study group than control group with a highly significant difference (P <0.01). Higher concentrations of salivary phosphorus, copper and total proteins were recorded among study group compared to control with statistically highly significant differences concerning phosphorus and copper (P<0.01). On the other hand, salivary calcium and zinc were lower among study group compared to control group with statistically highly significant difference concerning zinc (P<0.01). All the correlations between the caries experience and salivary constituents in the study and control groups were weak and not significant except the correlation with total proteins in the control group which was significantly positive. Concerning the correlations of oral hygiene and periodontal disease with salivary constituents, the study showed that all the correlations were weak and not significant except the correlations between the total proteins with loss of attachment in study group and with dental plaque in control group which were significantly positive relations.Conclusions : This study showed that the breast cancer patients had poor oral hygiene and higher rates of periodontal diseases and dental caries, therefore special preventive programs need to be designed for this group of patients. Also the results of this study could support the concept that salivary oncentrations of CA15 - 3 might serve to be used in the detection of breast cancer and/or the po operative follow - up of patients under treatment for carcinoma of the breast

تاثير انواع مختلفة من المواد الملونة على الاستقرار اللوني للحاصرات التقويمية الخزفية المرتبطة مع انواع مختلفة من المواد اللاصقة الضوئية التصلب : دراسة مختبرية Effect of Different Staining Materials On Color Stability of Sapphire Brackets Bonded With Different Types of Light Cure Orthodontic Adhesives (An In Vitro Study)

اسم المؤلف: الاء فالح البو حسن
اسم المشرف: نضال حسين غايب
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: لقد ازدادت الحاجة الى استعمال الاجهزة التقويمية التجميلية في هذه الايام مما دفع مقومي الاسنان الى البدء باستخدام الاسلاك التجميلية والحاصرات التجميلية بالاضافة الى الاشرطة المطاطية التجميلية.الحاصرات التقويمية الشبيهة بلون الاسنان انتجت من انواع مختلفة م | The demand for better esthetic during orthodontic treatment has increased now a days, so orthodontists starting using esthetic arch wires, brackets and ligatures.Tooth colored brackets were introduced in different types of materials.Sapphire ceramic brackets are one type of esthetic brackets and their color stability remains the main concern for the clinicians and patients at the same time.The present study design to evaluate the effect of three different staining materials (black tea, pepsi and cigarette smoke) on the stainability of sapphire ceramic brackets bonded with three types of light cure orthodontic adhesives whichinclude : Resilience, Enlight and Transbond. The sample consisted of three hundred sixty sapphire brackets. The brackets were divided according to bonding materials into three groups each group consist of one hundred twenty brackets, then each subgroup further subdivided into four groups according to the material they were immersed (distilled water, black tea, Pepsi and cigarette smoke) with thirty brackets each, then each group with ten brackets further subdivided according to time interval of immersion in each media into three groups one day, seven days and fourteen days at 37°C in the incubator. A UV - Visible spectrophotometer (Shimadzu, UV - 1800) was used to perform a light absorption test.ANOVA and LSD tests were used to identify the significant effects of the staining materials at a significance level P ? 0.05.It was found that the immersion time gradually influenced the color stability of the adhesive materials with sapphire brackets with the highest activity observed at fourteen days interval. The brackets bonded with Resilience light cure adhesive are the most type affected by staining materials, then followed by the brackets bonded with Transbond and finally the brackets bonded with Enlight lightcure adhesive.For the staining materials it was found that the cigarette smoke is the mostpowerful staining material, followed by tea and finally pepsi.From the above result we can conclude that the type of adhesive must takein consideration when the esthetic brackets have been used.

دراسة المضاعفات الفموية الوجهية, مؤشرات عامل - الغلوبيولين المناعي اللعابي A , الانترليوكين 6 وعامل تنخر الورم الفا في لعاب مرضى بيتا ثلاسيميا الكبرى في محافظة ميسان Study of Orofacial Complications, Salivary IgA, Interleukin - 6 And Tumor Necrosis Factor - Alpha Markers In Saliva of Beta - Thalassemia Major Patients In Missan Governorate

اسم المؤلف: جمال محبس ديوان
اسم المشرف: زاهدة جاسم محمد
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الثلاسيميا نوع بيتا هو الاضطراب الاحاد اليين الاكثر شيوعا في الشرق الاوسط، والتي تتميز بشذوذ في تركيب سلاسل بيتا من خضاب الدم مما يؤد الى ظواهر متفاوتة تتراوح بين فقر الدم الشديد الى عدم وجود اعراض سريريا.اهداف الدراسة : تحديد مدى انتشار المضاعفات الفمو | Beta - thalassemia is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. Several immunological defects can be found in patients with beta - thalassemia major patients, among which circulating cytokines levels, impairment of neurophil, macrophage phagocytic and killing functions, this impairment may be due to iron over load.Aims of study : Aims of this study was to evaluate the prevalence of Orofacial complications in beta - thalassemia major patients, salivary flow rate, salivary levels of salivary immunoglobulin A, interleukin - 6 and tumor necrosis factor alpha and to evaluate correlations between salivary parameters (salivary immunoglobulin A, interleukin - 6, tumor necrosis factor alpha and salivary flow rate) in beta thalassemia major patients.Methods : Sixty subjects were participated in this study, they were divided into two groups, patients group composed of 30 patients with major beta - thalassemia, age rang (5 - 23), and 30 healthy looking subjects of both sexes as a control group, age rang (5 - 25). Data was collected using a special formula for general, medical and Orofacial examination sheet. Whole non - stimulated saliva was collected, measured and analyzed by enzyme linked immmunosorbent assay.Results : Most patients were in the first and second decade of life (90%), 20 (60%) were males and 10 (40%) were females with an age rage (5 - 23 years). The prevalence of Orofacial complications in beta - thalassemia major patients increased with age.The prevalence of orofacial complications in beta - thalassemia major patients were color change of oral mucosa (73.3%), rodent face (66.7%), maxillaryprotrusion (66.7%), saddle nose (63.3%), deep bite (26.7%)), open bite (13.3%) and spacing (10%).Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013).Laboratory investigations for salivary concentration of interleukin - 6, tumor necrosis factor alpha and salivary immunoglobulin A revealed highly significant to significantly in mean of these parameters in beta thalassemia major patients as compared with control group, interleukin - 6 (p=0.001), tumor necrosis factor alpha (p= 0.01) and salivary immunoglobulin A (p= 0.05) at P value ? 0.05.Conclusions : Beta - thalassemia major patients have specific Orofacial complications and a particular salivary cytokines compared to normal individuals.

سمك العظم الشدقي في مناطق مختلفة من الفك السفلي واهميتة السريرية في تثبيت المسامير الحلزونية احادية القشرة باستخدام جهاز الاشعة المقطعية متعدد الشرائح Thickness of Buccal Bone At Various Sites of Themandible And Its Clinical Significance In Monocortical Screws Placementusing Multislice Computed Tomography

اسم المؤلف: حوراء نوري عطا لله
اسم المشرف: لمياء حامد النقيب
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: اشعة الفم والاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Open reduction and internal fixation (ORIF) using miniplates and screws is the treatment of choice for mandibular fractures.Using miniplates and screws along the ideal line of osteosynthesis provides sufficient support and stability to the bone fragments to allow immediate function. It is important to know both : the region where the bone providesafirm anchorage for the screw,andthe topography of thedental apices and inferior alveolar nerve to avoiddamaging them when inserting the screwThe aim of study : The purpose of this study is to determine the thickness of buccal cortical plate and that of buccal bone using computed tomography,at the parasymphysis and mandibular body, thereby determining the area that provide afirm anchorage and the maximum length of mono - cortical screws that can be safely placed in these regions without injuring the tooth roots orinferior alveolar nerve.Materials and Methods : The sample of the present study was a total of 110 Iraqi patients (77 males & 33 females) aged (18 - 35) years old who admitted to Computed Tomography scan unit in AL - SadrTeaching Hospital in Al - Najaf city to getComputed Tomographic examination of facial bones from November 2013 to May 2014. The conventional section of CT (axial) wasused to do the measurements and dental planning analysiswhich is a specific investigation protocol was also used.The thickness of buccal cortical plate and the thickness of buccal bone were measured at the level of root apex of (canine, first premolar, second premolar) and at the level of : root apex and inferior alveolar canal in (mesial and distal root of first and second molar). Results : The mean buccal bone thickness at canine area was (3.7 - 4.3 mm), in premolars area (3.6 - 4 mm), in molar area (at the level of apex) (5.6 - 6 mm), in molar area (at the level of inferior alveolar canal) (5.2 - 5.6 mm) for females and males respectively. The mean buccal cortical plate thickness at canine area was (1.4 - 1.6 mm), in premolars area (1.5 - 1.7 mm), in molar area (at the level of apex) (2.4 - 2.6 mm), in molar area (atthe level of inferior alveolar canal) (2.4 - 2.3 mm) for females and males respectively.There was no statistically significant age and gender difference in buccal cortical plate thickness and buccal bone thickness. Conclusion : Buccal cortical plate thickness and buccal bone thickness in various sites of the mandible could be measured precisely using Multislice Computed Tomography which can guide surgeons in selecting the proper screw length without causing injury to rootapex or inferior alveolar nerve.

تاثير الجنس،العمر وفقدان السن على ابعاد القناة الثاقبة والعظم الامامي للقناة : دراسة بالتصوير المقطعي Effect of Gender, Age And Tooth Loss On The Dimensions of Incisive Canal, And Buccal Bone Anterior To The Canal (Computed Tomography Study)

اسم المؤلف: رياحين غازي رشيد
اسم المشرف: احلام احمد فتاح
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: اشعة الفم والاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: القناة الثاقبة تركيب تشريحي لھا موقعا ھاما في الفك العلوي الامامي، دراسة خصائص ھذه القناة وتقييم علاقتھا مع العظم الامامي للقناة ضروري خلال زرع القواطع المركزية العلوية. الاشعة المقطعية لھذه المنطقة يمكن ان توفر ميزات دقيقة عن حدود وموقع القناة الثاقبة | The incisive canal is an anatomical structure with an important location in the anterior maxilla, analyzing this canal characteristics and evaluated its relation to the bone anterior to the canal is necessary during dental implantation of maxillary central incisors. CT scan image for this region can provide accurate features about the border, position of incisive canal and status of buccal bone anterior to this canal.Aim of the study : To study for the effect of gender, age and tooth loss in area of maxillary central incisors teeth on the dimensions of the incisive canal and buccal bone anterior to the canal using spiral computed tomography.Subjects, Materials and Methods : The sample consisted of prospective study for 156 subjects of both gender. The sample were divided into two groups, 120 dentate group (60 male and 60 female) with age ranging from (20 - 70) and 36 edentate group(with missing both maxillary central incisor) (18 male and 18 female) with age ranging from (50 - 70), which was further divided into two group according to the duration of maxillary central incisorsteeth loss, long duration (5+) years which consists of 26 subjects and short duration (<5 years) which consists of 10 subjects. All subjects attended to Baquba Teaching General Hospital in Diyala for Computed Tomographic scan investigation for different Maxillofacial diagnostic purposes from November/2013 to April/2014.Using sagittal section of computed tomography scan, the following measurementswere done : A - The diameters of incisive canal were measured at crestal, middle and apical level and the total mean value of canal diameters was calculated. B - The length of incisive canal.C - The distance of buccal bone anterior to incisive canal at crestal, middle and apical level and the total mean value of buccal bone distances was calculated. D - The length of buccal bone anterior to incisive canal from the apical measurement of buccal bone to the alveolar crest. The measuring unit was in millimeter in all measurements.Result : Gender had moderately strong effect on the dimensions of incisive canal and buccal bone anterior to this canal, the mean values begin generally higher for male as compared to female for both control and cases group. Absence of maxillary central incisors decreased incisive canal length and buccal bone dimensions with mean values begin higher in control group than that in cases group, the effect of teeth loss on these selected measurements seem to be strong ;however, canal diameter remain unchanged with dental status and there was no effect of teeth loss on this parameter.There was a moderately strong to strong effect of the duration of maxillary central incisors teeth loss on canal length and buccal bone dimensions with mean values being significantly lower in long duration (5+) years than that in short duration (<5 years) while it had weak effect on incisive canal diameter for both gender. The results showed that there was no significant linear correlation between age and all selected measurements in male and female for both control and cases group. Conclusion : CT scan is a valuable tool to evaluate the anatomic variation at the examined area in the current study, gender and dental status are important factors that can affect incisive canal characteristics and amount of bone anterior to the canal. Clinicians should perform careful planning using CT scans before performing dental implant surgeries in premaxillary region.

قياس كثافة العظم السنخي في الفك العلوي في سن 13 - 15 سنة باستخدام المفراس الحلزوني Measurment of Maxillary Alveolar Bone Density At 13 - 15 Years Age Using Spiral Omputerized Tomography

اسم المؤلف: ازهار عبد الامير فرج
اسم المشرف: فخري عبد علي الفتلاوي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Bone density is a major factor that affect mini implant primarily stability. No Iraqi studies had been evaluated bone density related to mini - implant placement for orthodontic anchorage at age 13 - 15 years.The present research aims to evaluate gender, side and site differences in the bone density at various orthodontic implant sites for the maxillary alveolar bone (cortical; buccal and palatal and cancellous).The sample of this study consisted of CT images for patients who were attending Al. Shaheed Ghazi Al - Hariri Hospital/the Computerized Tomography department from January 2014 until May 2014. Twenty nine individuals (16 males and 13 females) had subjected to clinical examination, then 64 - multislice computed tomography scan data were evaluated and bone density was measured in Hounsfield unit at 21 points (9 points for each side and 3 points between the right and left central incisors).The results obtained showed that there were no significant differences in bone density between males and females and between the left and right sides. There are no significant differences in bone density between the maxillary buccal cortical bone and the palatal cortical bone except at lateral incisor and canine point where the palatal side had higher bone density than buccal side. The mean bone density of the cancellous bone in the anterior part was higher than that in the posterior of the maxilla.These differences in bone density between and within regions of the maxilla must be considered when placing mini implants and may provide valuable information when selecting sites, size, angle and placement methods for mini implant in the dental arch.

حاله الاكتئاب وعلاقتها بحاله الفم والخصائص الفزيوكيميائيه لدى طلاب المدارس من فئه عمر 15 سنة في مدينة الصويره - حافظة واسط - جمهورية العراق Depression Status In Relation To Oral Health Condition And Salivary Physiochemical Characteristics Among 15 Years Old School Students In Al - Swera City - Wassit Governorate - Iraq

اسم المؤلف: هدى سلمان خیاله
اسم المشرف: بان صاحب ذیاب
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان الوقائي
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Depression is a common mental disorder that presents with depressed mood, its affect oral health through its effect on salivary function. The aims of this study were to assess the relation of depression status on prevalence and severity of dental caries and gingival inflammation among students aged 15 years in relation to salivary physical (flow rate and viscosity) and chemical characteristics concentration of (total protein, zinc, copper, chromium and lithium).Materials and methods : The total sample involved 800 students (males and females) aged 15 years old that were selected randomly, the depression status was measured using Children Depression Inventory (CDI) index that divided the students with depression into four groups according to severity of depression (low or average grade, high average grade, elevated grade and very elevated grade). The diagnosis and recording of dental caries was made by using Decay, Missing, Filled surface index (DMFs), according to the criteria of Manji et al (1989), while gingival condition was evaluated by using the gingival index by L?e and Silness, (1964). Salivary samples were collected under standardized condition from 30 students with very elevated grade and 30 students with low average grade, and then analyzed for measuring salivary flow rate and viscosity, in addition to the estimation of salivary elements (total protein, zinc, copper, chromium and lithium).Results : The prevalence of depression was 100%. The DMFs was lower among students with high average grade than other grades of depression with nonsignificant difference. The severity of dental caries was higher among students with elevated grade concerning D1, D3 and in very elevated grade of depression concerning D2, D4 with highly significant among D4 (P = 0.01). The prevalence of gingivitis in present study was found to be 100%, mild gingivitis occurrence found higher among low or average grade than other grades, but moderate gingivitis was more among very elevated grade, while sever gingivitis was absent. Salivary analysis demonstrated that the salivary flow rate was non significantly higher among students with low or average grade of depression than very elevated, while the viscosity of saliva was not significantly higher among students with very elevated grade. The data analysis of salivary elements found that the total protein and copper was higher among students with very elevated grade while other elements show the opposite result with significant difference concerning copper and zinc among females in very elevated grade, while others with not significant.Conclusion : The results of the current research revealed that caries experience and gingival inflammation increase with depression that has an adverse effect on salivary physicochemical characteristics. There were changes in saliva variables between low or average grade and very elevated grade of depression.

تاثير متسلل التسوس ممزوج مع او بدون مواد لاصقة تقليدية على ختم المينا السليمة : دراسة مختبرية The Influence of Caries Infiltrant Combined With And Without Conventional Adhesives On Sealing of Sound Enamel (In Vitro Study)

اسم المؤلف: مروة بلاسم محمد الجيبةجي
اسم المشرف: ضياء جعفر الدباغ
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: The formation of white spot lesions around fixed orthodontic attachments is a common complication during and following fixed orthodontic treatment, which hinder the results of a successfully completed case.The aim of the study was to assess the effectiveness of the Caries Infiltrant (ICON®) on prevention of caries on the smooth enamel surface when applied alone or combined with conventional adhesives. To achieve this objective, seventy eight human premolar enamel discs were randomly assigned to six groups (n=13). The discs were etched and treated with resins of different monomer content forming the following groups : (1)Untreated etched samples served as the negative control, (2) ICON® (DMG), (3) Adper™ SB 2 (3M ESPE), (4) Heliobond (Ivoclar Vivadent), (5) ICON®+ Adper™ SB 2 and (6) ICON®+ Heliobond. Specimens were subjected to demineralization by immersion in hydrochloric acid (pH 2.6) for 18 days. Calcium dissolution into the acid was assessed by photometric test via spectrophotometer at 24 hour intervals.The results revealed that, there was a highly significant difference between the sealed groups and the unsealed (untreated) one (p?0.00) indicating that the unsealed specimens showed the highest amount of Ca ion loss among all other groups. Additionally, there was no significant difference between untreated specimens and the ICON® sealed ones. While, Heliobond decreased the Ca ion loss significantly compared to the untreated specimens and Adper™ SB 2 performed significantly better than both ICON® and Heliobond. Furthermore, the combination of ICON® with either Adper™ SB 2 or Heliobond served as the best protective measures and maintained the protective effect during the whole experiment period.Therefore, within the limitations of this in vitro study, it could be concluded that the use of low - viscosity Caries Infiltrant prior to application of the tested conventional adhesives increases their protective effect against demineralization.

تقييم تاثير بلازما النيتروجين المتوهج لغرسة التيتانيوم التجاري على الترابط العظمي بالتحليل الميكانيكي والتحليل النسيجي Evaluation of The Effect of Glow Plasma Nitriding of Commercially Pure Titantium Dental Implant On Osseointigration Through Mechanical And Histomorphometric Analysis

اسم المؤلف: حسن جواد فرحان المسعودي
اسم المشرف: شذى سليم الامير
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الاتجاه الجديد للغرسات هوايجاد المواد التي تسرع عملية بناء العظم في السطح البيني للعظم والغرسه وتحسين الاندماج العظمي من اجل توفير التحميل الفوري والمباشر بعد وضع الغرسات وتقليص فترة الانتظار التي تكون مزعجه وغير مريحه للمرضى.الاهداف.تقييم تاثير طلاء ال | Introduction : The new trend of implants is to find materials which accelerate bone formation in bone implant interface and improve osseointegration to provide immediate or early loading after placement in addition to eliminate the waiting period which is usually uncomfortable and disturbs patients. Aim of study : To evaluate the effect of plasma nitride treatment of screw shaped commercially pure titanium dental implant on bond strength at bone implant interface by torque removal test and histomorphometric analysis after 2 and 6 weeks in comparison to non treated one.Materials and methods : Commercial pure titanium plates and screws were plasma nitrided for 10h using glow plasma nitride apparatus. X - ray diffraction (XRD) analysis , scanning electron microscope examination were carried out on the nitride surfaces of the plates ,contact angle measurement (Wettability) was done by applying drop of saline and blood on the nitrided surface and compared to control. The femur of 10 white New Zealand rabbits were chosen as implantation sites. The femur of each rabbit received two screws, one plasma nitride treated and one non treated and a total of 40 screws were implanted. Torque removal test was performed(by digital torque meter) to measure bond strength between implant and bone, after 2 and 6 weeks healing periods. For each period of time 18 screws were tested for the torque required to remove the implant from the bone and 2 screws were kept for histological examination. Results : The results revealed that the mean removal torque values for the plasma nitride treated implants was significantly higher than the non treated implants and over the two periods of time. There was an increase in the bond strength (torque value) of bone - implant interface with time. The torque removal force for plasma nitride implants after 2 and 6 weeks was (30.22, 59.56 N.cm ,respectively) and for non treated implants after 2 and 6 weeks were ( 23.61,56.11N.cm, respectively) and new bone formation ratio for plasma nitride treated implants after 2 and 6 weeks(3.36, 4.72 , respectively) and for non treated after 2 and 6 weeks(1.56, 3.04, respectively). Conclusion : Plasma nitriding of Cp Ti screws significantly increased the torque removal value and new bone formation ratio at 2 and 6 weeks compared with the non treated implant.Dental implant, Osseointegration, Digital torque meter

مواصفات الاطباق وادراكه والحاجة والطلب على تقويم الاسنان لدى الطلاب البغداديين بعمر 13 سنة : دراسة مقارنة مسحية ميدانية Occlusal Features, Perception of Occlusion And Orthodontic Treatment Need And Demand Among 13 Years Aged Baghdadi Students (A Comparative Cross Sectional Epidemiological Study

اسم المؤلف: زينب محمد رضا الجلبي
اسم المشرف: فخري عبد علي الفتلاوي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: The study was conducted to assess the distribution, prevalence, severity of malocclusion and orthodontic treatment need in Baghdad governorate in relation to gender and residency, and whether it has increased or not over 12 years by comparison with previous survey in Baghdad.A multi - stage stratified sampling technique was used in this investigation to make the sample a representative of target population. The sample consisted of 2700 (1349 males and 1351 females) intermediate school students aged 13 years representing 3% of the total target population.A questionnaire was used to determine the perception of occlusion and orthodontic treatment demand of the students and the assessment procedures for occlusal features by direct intraoral measurement using veriner and an instrument to measure the rotated and displaced teeth. In summary the followingresults were obtained : 1 - 7.7% of the sample had some type of orthodontic treatment or consultation.2 - 39.1% of the students answered that they have malaligned teeth, being significantly more in female than males.3 - of the students who stated that they have malaligned teeth, 26% reported that they had crowded teeth, 26.6% had spaced teeth, 22.4% had protruded teeth and 25.7% had rotated and displaced teeth.4 - Regarding the answers of the effect of mal - aligned teeth, 70.3% answered that it affects their appearance, 17.7% chewing, and 7.7% speech while 4.1% answered that mal - aligned teeth did not affect appearance, chewing or speech.5 - the most common reasons for not seeking orthodontic treatment that the student thought that treatment is fear of pain (48.8%) and not important or not possible (25.8%).6 - One or more missing teeth due to extraction or trauma were found in 4.9% of the sample, and the most common extracted teeth were the first molars (1.6% mandibular and 0.9% maxillary). One or more rotated teeth were found in 38.3% of the sample; one or more displacement teeth were found in 19.6% of the sample.7 - The maxillary anterior region showed the highest prevalence of 2mm or more spacing (15.2%) and the mandibular anterior region showed the highest prevalence of 2mm or more crowding (12.6%); a maxillary central diastema of 1mm or more was found in 18.1% of the sample with a mean of 0.306±0.015mm.8 - Angle’s class I occlusion was found in 78.29%of the sample, class II in 19.5% (17.2% division 1 and 2.3% division 2) and 2.3% had class malocclusion (1.6% postural and 0.7% true). The mean overjet of the sample was 3.31± 0.04 mm. The mean overbite was 2.99±0.03 mm,9 - Midline shift (?1mm) was found in 54.3% of the sample (28% to the right and 26.3% to the left side).Soft tissue impingement was found in 3.3% (3% palatally and 0.3% labially). Normal lip form was found in 86.6%, contracting lip form in 10.1% and lip trap in 3.3% of the sample.10 - The DAI scores registered in this study ranged between 13 and 65 with a mean of 23.234±0.12. 7.3% with treatment highly desirable, and 4.5% with treatment mandatory.Significant changes in the proportions of malocclusions as a whole in school children were found over the last decade; also increase the need for orthodontic treatment among adolescents in the Baghdad commune and low perception level of the Baghdadi children to their own occlusion and the demand on treatment was remarkably low. This data will be useful for public oral health service and emphasize the need for orthodontic treatment among adolescents in Baghdad and stressing on the role of oral health education to encourage the children to undergo orthodontic treatment.

تاثير اضافة فلوريد الصوديوم كمطهر على بعض خواص مادة طبعة الالجنيت Effect of Sodium Fluoride Addition As A Disinfectant On Some Properties of Alginate Impression Material

اسم المؤلف: علاء مهدي حسين
اسم المشرف: رغداء كريم جاسم
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: صناعة الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: المقدمة : تلوث طبعات الاسنان مع اللعاب والدم من تجويف الفم يحصل مباشرة في عيادات الاسنان ومختبرات صناعة الاسنان يجعل من طبعات الاسنان الملوثة فقرات يصعب التعامل معها من وجهة نظر انتشار الاخماج. اشارت التقارير السابقة الى امكانية الطبعات الملوثة بتلويث ال | Introduction : Contamination of dental impressions with saliva and blood from the oral cavity occurs readily in dental clinics, direct interaction between dental clinics and dental laboratories makes contaminated dental impressions difficult items to deal with it from the cross contamination point of view. Previous reports indicated that contaminated impressions can cross infect gypsum casts that were poured against them, however immersing or spraying commonly used alginate impression material with disinfectant may adversely affect the accuracy of dies or casts obtained. Objective : The objective was to evaluate the effect of (0.25%,0.5%,1%, 2%, 3%, 4% ) of (NaF) addition on the self - disinfection of alginate impression material and its effect on setting time, tear strength, dimensional change and accuracy of alginate impression materials and to compare this with CHX containing alginate material related to the same properties mentioned above.Materials and methods : A total No. of 800 specimens were prepared in this study, they were divided into five main groups according to the type of the tests used (tear strength test, setting time test, dimensional change test, dimensional accuracy test, and bacteriological tests (Streptococcus mutans and Candida albicans).Six concentrations of NaF from (0.25% to 4%) and 0.1% CHX gluconate were mixed with alginate impression material and compare it with control alginate without disinfectant. Results : The self - disinfecting impression material containing NaF showed a total kill of microorganisms immediately after impressions were made.Tear energies for all experimental impression materials were greater than those of the control products. There were no statistically significant differences between the dimensional change tests and also reproduction of detail test, that contained (NaF) and one that did not. With regard to setting time of the impressions, statistically significant reduction were seen between the control and experimental groups of alginate impression materials. The experimental material that did not contain (NaF) had a considerably longer setting time than all of the other materials tested.Conclusion : the use of (NaF) and CHX disinfection when taking alginate dental impression is a good measure in reduction of contamination and cross infection and have a minute effect on dimensional stability and is recommended as step in protecting dentist and dental laboratories teams.

التاثير السمي للضوء الازرق المرئي على البكتيريا المشعشعة المصاحبة للورم الفطري والبورفيروموناس اللثوية في المرضى المصابين بالتهاب اللثة المزمن : دراسة مختبرية Phototoxic Effect of Visible Blue Light On Aggregatibacter Actinomycetemcomitans And Porphyromonas Gingivalis In Patients With Chronic Periodontitis (An In - Vitro Study

اسم المؤلف: علي رعد عبد العزيز
اسم المشرف: مها شكري محمود وفاق محمود الوتار
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: امراض ما حول الاسنان
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الخلفية : على الرغم من ان ازالة الصفائح الجرثومية (الجير) وكلس الاسنان ( الحصى السنية ) بالطرق الميكانيكية يمثل حجر الزاوية في علاج امراض اللثة، يبقى ذلك بحاجة الى علاج مساند اذا علمنا ان التنظيف الميكانيكي لا يستطيع الوصول الى كل السطوح والاماكن حول السن | Background : Although mechanical debridement of dental plaque and calculus represents the corner stone in periodontal treatment , still it needs an adjunctive therapy since mechanical cleaning cannot reach all the surfaces and sites all around the tooth and within periodontal defect or the bacteria that resides inside periodontal tissues. Chemotherapy been used as an adjunctive therapy alongside with mechanical debridement in different compositions and routes, i.e. : chlorhexidine mouth washes (local routes) , antibiotics (systemic route) , yet chemical treatment might not be sufficient or cannot be used as in cases of drug sensitivity , difficulty to maintain effective concentration at wanted sites and lack of patient dexterity and compliance.Hence, arises the need for an alternative adjunctive therapy, photodynamic therapy has been used in recent years, taking advantage of the toxic effect of light on periodontal pathogens (bacteria). Aims of the study : The purpose of this study was to determine the toxic effect of visible blue light emitted from dental curing led light device of wavelength ranges between 400 - 500nm and energy of 1000 - 1200 mw/cm on the viability of periodontal pathogens (Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis), alone once , and with combination of 0.2% chlorhexidine mouthwash in vitro.Materials and methods : A.actinomycetemcomitans and P. gingivalis, was obtained from periodontal pockets of patient suffering from periodontitis by removing the plaque carefully to be cultured under anaerobic conditions for 3 days in suitable culture media using anaerobic jar in the incubator, presence of the wanted micro - organism is confirmed using Gram stain and biochemical activity tests.The amount (quantity of bacteria) was determined by direct colony counting and using visual software aids (open CFU software program) when needed.Visible blue light (LED curing light) from a commercially available device the same used in light - cured fillings in dentistry was used to generate a beam of visible blue light with amount of energy 1000 - 1200 mW/cm2 of a wavelength ranges between 400 - 500nm. Samples were subjected to blue light for increasing time intervals and were subcultured after each exposure.Same procedure of light exposure was repeated on plates containing chlorhexidine mouth wash in holes created with pasture tube, a standardized amount of chlorhexidine (0.1mml) was administrated into the holes of each plate, and then the inhibition zone was measured repeatedly for each plate after 72 hours of anaerobic incubation.

تسوس الاسنان والاحتياجات العلاجية لطالبات الثانوية لعمر (16 - 18) سنة وعلاقتهما مع نظافة الفم، المستوى الدراسي للاهل والتحليل الغذائي في مدينة المسيب/ محافظة بابل/ العراق Dental Caries And Treatment Needs Among 16 - 18 Years Old High School Girls, In Relation To Oral Leanliness, Parent'S Education And Nutritional Status, In Al - Mussayb City/ Babylon Governorate/ Iraq

اسم المؤلف: زهراء محمد حسین
اسم المشرف: سلافة خالد السامرائي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان الوقائي
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Dental caries is a quite prevalent disease in Iraqi community however, baseline data concerning this disease and related etiological and risk factor are limited, concerning in selected geographic area in Iraq.Aims of study : This survey was made to investigate the prevalence and severity of dental caries in Al - Mussayb city/ Babylon governorate, the co - relation of this disease was studied with nutrition status and dietary analysis, oral cleanliness and parent'seducation among (16 - 18) years old in high school girls.Materials and Methods : The survey was conducted among high school girls, with a total sample of 900. Diagnosis and recording of dental caries and treatment needs were done according to the criteria of WHO. Dental plaque was assessed by using Plaque Index following the criteria of Silness and Loe. Nutritional status was recorded according to Body Mass Index indicator by applying anthropometric measurement. Dietary analysis was according to Dietary Guidelines in primary health centers in Iraq. Parent's education was divided in to five levels according to modification to educational status of Kuppuswamy's scale.Results : The prevalence of dental caries was (70.5%). The DMFS mean value was (4.94 ±SE 0.161) and the median was equal to (4.00) for the total sample. The DMFS value increased with ages with statistically highly significant difference (P<0.01), The highest percentage of examined girls were in need of one surface filling (60.8%), followed by those in need of two or more surface filling (36.6%). Result showed a weak positive highly significant correlation between plaque index and DMFS (r=0.315, P<0.01). A statistically highly significant difference in DMFS was recorded by different level of parent's education as a lower value of DMFS was seen among girls with high level of parent's education. Results showed statistically highly significant differences in the value of DMFS between different grade of Body Mass Index indicator (P <0.01, df=3), for total sample (11.7%) was malnourished and (65.77%) of girls was with normal weight. Statistically highly significant weak negative correlation was seen between DMFS and different food groups (fruits, vegetable, meat, grain and diary). A weak positive highly significant correlation between DMFS and sweet consumption was seen (r=0.155, P<0.01).Conclusions : Girls in high schools in Al - Mussayb city/ Babylon Governorate demonstrated a high prevalence of dental caries. Nutritional status, dietary habits, oral cleanliness and parent's education were found to affect the severity of this disease, thusthere is a need for public and school preventive programs among those population

ابعاد البلعوم فيما يتعلق ببعض المتغيرات السنية والقحفية للصنف الهيكلي الاول والثاني : دراسة مقارنة بالاشعة القياسية الجانبية عند البالغين Nasopharyngeal Dimensions In Relation To Some Dento - Cranium Variables of Class I And II Skeletal Patterns (A Cephalometric Comparative Study In Adults)

اسم المؤلف: عمار عباس فضل
اسم المشرف: فخري عبد علي الفتلاوي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: The size of the nasopharyngeal airway was believed to have an important role in the development of the dentofacial structure. Therefore, this study was done on 60 subjects (30 males and 30 females) at age range 18 - 25 years. Cephalometric radiograph has been taken to each subject and the measurements were recorded. The sample was divided into two groups, class I skeletal relationship (15 males and 15 females) and class II skeletal relationship (15 males and 15 females). Comparisons between the different study groups were undertaken and the following results were obtained.In class I skeletal relationship, all the nasopharyngeal liner measurements and all the dento - cranium linear measurements are significantly higher in males than females, except lower airway thickness (PNS - ad1) and upper airway thickness (PNS - ad2)showed no significant gender difference. While all the angular measurements showed no significant gender difference.In class II skeletal relationship, most of the nasopharyngeal liner measurements have no significant gender difference, while all the dento - cranium linear measurements are significantly higher in males than females. In comparison for class difference between class I and class II skeletal relations in total sample, all the nasopharyngeal linear measurements have no significant class difference, except lower airway thickness showed significant difference which were higher in class II than class I and upper airway thickness showed significant difference which were higher in class I than class In the whole sample of the study, positive correlation was found between lower airway thickness and upper airway thickness.

معدل انتشار وشدة نقص التمعدن الضرسي القاطعي والعلاقة مع العوامل المسببة بين اطفال المدارس بعمر 7 - 9 سنة في محافظة النجف Prevalence And Severity of Molar - Incisor Hypomineralisation In Relation To Its Etiological Factors Among School Children Age 7 - 9 Years In Al - Najaf Governorate

اسم المؤلف: ولاء عامر عوفي
اسم المشرف: بان علي صالح
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب اسنان الاطفال
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Molar - Incisor hypomineralisation (MIH) is one of the biggest challenges with great clinical interest for dental practice because MIH has a great impact on the oral health as consequently, on the quality of life of children. Currently, the etiology of MIH remains unclear and is thought to be acquired via multifactorial, systemic disturbances during amelogenesis. There is no previous study concerning school children aged 7 - 9 years in Al - Najaf govemorate in order to estimate the prevalence and severity of molar incisorhypomineralisation and the possible associated risk factors. Objective : To estimate the prevalence , severity and the possible associated etiological factors of molar - incisor hypomineralisation and also to study the correlation between body mass index and molar - incisor hypomineralisation.Patients and Methods : A cross sectional study was conducted at Al - Najaf Govemorate, data were collected during the period from January to the end of April 2014. study population included the primary school children aged, 7 - 9 years of both genders who attending the primary schools of Al - Najaf govemorate. Children having amelogenesis imperfecta, tetracycline staining or undergoing orthodontic treatment at the time of study, those with completely broken crowns of the first permanent molars, or those whose parent/guardians refusedto missed data or not get back the questionnaire were excluded from the study. Sample size was calculated according to the standard equation and a total of 600 children were enrolled. A structured self - administered validated arabic language questionnaire and an examination sheet was measured. Body weight and height were measured and the body mass index was calculated according to the standards. Dental material and supplies were used in examination, Prior to the clinical examination the participating children were given a toothbrush and fluoridated toothpaste to brush their teeth thoroughly under the supervision of the researcher. The demarcated hypomineralization was recorded according to the 10 point scoring system depended on the European academy of pediatric dentistry evaluation criteria. The severity was assessed according to the clinical evaluation of the examiner and the presence of opacities. Data of the studied group were entered and analysed by using the statistical package for social sciences (SPSS) version 21 and appropriate statistical tests were used to assess the differences and correlations between variables. Results : The response rate was 84. 7% and the highest was in the 9 - year - old children, the participants were 532 children, the prevalence of hypomineralisation defect was 22.9%. The prevalence of demarcated hypomineralisation was increased concomitantly with the age, and the 9 - yearold children were the more affected. The overall prevalence of molar - incisor hypomineralisation among boys was lower than girls; (17.3%) and 22.6%, respectively. Molar - incisor hypomineralisation was more frequent in normal body mass index children. The total number of teeth of the studied group was 1464. The number of affected teeth was 3 81 represented (26%) of the total number of teeth. The molar and incisors were most affected with White/creamy demarcated opacities with no posr eruptive enamel breakdown, (27.7% and 15.2%), respectively. The severely affected teeth were 33 teeth, represented 4.5% of the total number of teeth of the 122 children , severely affected molars were 25 (5.1 %) and the severely affected incisors were 8 (0.8%), (P=0.001), Obeseand overweight were more likely to have more severely affected teeth and the severity was also increased with the age of child. Conclusions and Suggestions : The prevalence of Molar Incisor Hypomineralisation among Iraqi schoolchildren of Al Najaf govemorate was 22.9%, it was more prevalent among girls, the 9 - year - old children , normal body weight children and urban residents. Molars were more affected with than incisors. It was more prevalent in maxillary than mandibular teeth. The severely affected teeth represented 4.5% of the total number of teeth of the 122 children. , molars were more severely affected than incisors. The more severely affected teeth reported inobese and underweight children. Further studies are suggested for further understanding of the etiological and risk factors of the disease.

الحالة الصحية للفم لاطفال الرياض وعلاقتها بالحالة الاقتصادية والاجتماعية في محافظة النجف الاشرف العراق Oral Health Status Among Kindergarten Children In Relation To Socioeconomic Status In Al - Najaf Governorate - Iraq

اسم المؤلف: سهى مهدي حميد شبر
اسم المشرف: وصال علي العبيدي
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب الاسنان الوقائي
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تقييم بعض مقاييس اللعاب المناعية وتركيز عنصر الحديد وعلاقتهما بحالة صحة الفم للاطفال المصابين بفقر دم البحر الابيض المتوسط النوع الكبير كربلاء/العراق Evaluation of Selected Salivary Immunological Parameters And Iron Ion Concentration In Relation To Oral Health Condition Among Children With Beta Thalassemia Major (Karbala’ / Iraq)

اسم المؤلف: شيرين سمير يوسف
اسم المشرف: بان علي صالح
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب اسنان الاطفال
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Beta Thalassemia Major is an inherited, genetic blood disorder which affect the bone marrow's ability to produce 2Themoglobin 2Tmolecules( the component of normal1T 1T2Tred blood cells1T2T 1Tthat transports oxygen to the body's cells), thered blood cells will have been short lifespan and 2Tdestroyed1T2T 1Tat a1T 1T2Tfaster rate2T. These patients are typically transfusion - dependent, and have significant complications, including iron overload, immune system disorders, and bacterial and/or viralinfections which can affect the oral health condition. Aims of the study : The aims of the present study were to assess the severity of dental caries, dental plaque, gingivitis, levels of selected salivary immunological components and iron concentration in saliva, among a group of boys and girls with beta thalassemia major in comparison with the control group.Materials and methods : The study involved 17 boys and 23 girls with beta thalassemia major, aged 8 - 9 years compared to 17 healthy boys and 23 healthy girls with the same age group. dmfs/ds and DMFS/DS indices (WHO, 1987), plaque index (Silness and L?e,1964), and gingival index (L?e and Silness, 1963) were applied, unstimulated salivary samples were collected for estimation the salivary immunological components(Secretory Immunoglobulin A, lysozyme, peroxidase, and lactoferrin) in which they were analyzed by enzyme - linked immune sorbent assay kits and iron ion concentration in saliva which was analyzed biochemically.Results : Results showed that, caries - experience was higher among beta thalassemia children compared to healthy children. In primary teeth, a higher dmfs/ds mean value was recorded for study group (dmfs/ds=8.93±6.40) compared to control group (dmfs/ds=6.63±5.38), the difference was statistically not significant (p>0.05), except for girls the difference was statistically significant (p<0.05). For permanent teeth, DMFS/DS mean value was found to be higher instudy group (DMFS/DS=0.63±1.23) compared to control group (DMFS/DS=0.58±0.75), and the difference was statistically not significant (p>0.05). plaque index mean value was higher in study group (PI=1.69±0.45) compared to control group (PI=1.52±0.28), and the difference was statistically significant (p<0.05). gingival index mean value was higher in study group (GI=1.38±0.20) compared to control group (GI=1.22±0.10), and the difference was statistically highly significant (p<0.01). Correlation between dental plaque and gingivitis in study group was positive with statistically highly significant(p<0.01). There were some variation in the levels of salivary immunological parameters between study and control groups, the differences were statistically not significant(p>0.05), except that for peroxidase, the levels were higher in study group compared to control group and the difference was statistically significant (p<0.05). Iron ion concentrations were higher in study group compared to control group, the difference was statistically not significant (p>0.05). The correlation between secretory immunoglobulin A levels and dmfs/ds in study group was statistically significant (r= - 0.32, p=0.02). Lysozyme was correlated with DMFS/DS in study group and the correlation was statistically significant (r=0.38, p=0.01). lactoferrin was correlated with dmfs/ds and DMFS/DS in control group, and the correlation was statistically highly significant and significant respectively (r=0.52, p=0.00), (r=0.32, p=0.04). The correlations between iron ion concentrations and dental caries were statistically not significant(p>0.05) for both groups. All the correlations between measured salivary parameters and dental plaque and gingivitis were found to be statistically not significant(p>0.05) for both groups. The correlations between iron ion and immunological components were statistically not significant(p>0.05). The correlation between lysozyme and lactoferrin was statistically significant in both study group and control group respectively (r=0.36, p=0.02) and (r=0.36, p=0.01). The correlation between peroxidase and lactoferrin in study group was statistically highly significant (r= - 0.40, p=0.00). In control group, there was statistically highly significant correlation between secretory immunoglobulin A and lactoferrin (r=0.41, p=0.00). Conclusion : dental caries, dental plaque and gingivitis found to be higher in beta thalassemia major patients than normal children; they need periodic dental examination and effective preventive program.

تقييم تاثير التيجان المقاومة للفولاذ (تقنية الهول) على معالجة التسوس للطواحن اللبنية : دراسة رجعية Evaluation of The Influence of Preformed Metal Crown ((Hall Technique)) On The Managing of Carious Primary Molars A Retrospective Study

اسم المؤلف: ورف محسن موسى
اسم المشرف: بان علي صالح
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: طب اسنان الاطفال
الدرجة: ماجستير
الجامعة: جامعة بغداد
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : When prevention of dental caries fails, and a child is exposed to the risk of pain and infection, the disease must be managed to reduce this risk. There is a growing evidence supporting more 'biological approaches' for managing dental cariesin primary teeth. The Hall Technique is one of the biological approaches for managing caries in primary molars which involves sealing caries beneath preformed metal crowns (stainless steel crowns). The crown is cemented over the tooth without theuse of local anesthesia, caries removal, or tooth preparation. The clinical steps for the Hall Technique are straightforward but, as with all dental care provision, appropriate treatment planning for the procedure requires skill. The Hall Technique offers anothermethod of managing early to moderately advanced, active carious lesions in primary molars, with good evidence of effectiveness and acceptability.Aims of the study : This study was conducted to assess the possible local factors that might happen along with using this novel technique regarding the possible adverse effect of the increased occlusal - vertical dimension and the condition of the surrounding tissues.Also to assess the correlation between the rate of the successful outcome with the caries extension towards the pulp.In addition to evaluate the cost - effectiveness of the Hall Technique in comparison with the conventional restorations. Finally to estimate whether this technique can be performed efficiently by both the specialized dentists and general practitioners in terms of putting the appropriate treatment plan based on the radiographic assessment.Material and methods : A retrospective research was conducted, standardized bitewing radiographs of 100 patients between 3 - 9 years old were evaluated for marginal bone changes. The distance between the cemento - enamel junctions and the alveolar bonecrest was measured. The dentine was evaluated as well regarding the existence of clear band of dentine and the extension of the caries towards the pulp of the tooth. - The cost effectiveness was conducted by creating a scenario of the possible outcomes for the treatment decision whether it was Hall preformed metal crown or traditional restoration. Incremental cost - effectiveness ratio was calculated to find the savingamount value. - A panel consisting of five general practitioners and three specialized dentists weas asked to evaluate twelve bitewings radiograph presented to them and give their opinion whether these radiographs are suitable for Hall Technique or not.Results : The result of this presented study showed that there is decreasing in the distance between the cemento - enamel junction and alveolar bone level at the Hall PMCs treatment side between the before and after insertion periods.it also showed thatthere's no different bone level changes between the Hall preformed metal crown treatment side and its contra - lateral side regardless of its condition (Hall preformed metal crowns, no Hall preformed metal crowns). - A high rate of successful treatment is highly associated with observing a clear band of dentine but it is not associated with the carious extinction toward the pulp as long as a clear band of dentine can be seen. - The Hall Technique is more cost - effective by making more cost saving and more gained teeth. The Hall Technique can be performed efficiently by both the general practitioners and the specialized dentist.Conclusion : according on the results of this research it can be settled that there are no adverse effects of using Hall preformed metal crowns regarding the increase of occlusalvertical dimension and the periodontal condition also the Hall Technique is more costeffective and can be performed by specialized dentists as well as the general practitioners.

تقييم تاثير وجود الكحول في الغسولات الفموية على تلاشي قوة السلاسل التقويمية المرنة المختلفة الاشكال : دراسة مختبرية Evaluation of The Effect of Alcohol Presence In Mouth Washes On Force Degradation of Different Configurations of Elastomeric Chains (An In Vitro Study)

اسم المؤلف: نور نوري عباس عبد الله
اسم المشرف: نضال حسين غايب
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Elastomeric chains are one of the most commonly used force delivery systems. They have the ability to exert an interrupted force, convenience of use, compatibility to oral environment and cost effectiveness despite of the inherited disadvantage which is force degradation.This in vitro study was designed to evaluate the effect of alcohol presence in mouthwashes on force degradation of different configurations of clear elastomeric chains from Ortho Technology company which are : closed, short and long under the effect of time at different intervals (Initial, 1day, 1, 2, 3 and 4 weeks) with exposure to different chemical solutions.A total of (540) elastomeric chains of three different types (long, short and closed) transparent in color, with an initial length (19mm) and about 50% extension (29mm) were used for the study. These elastomeric chains was divided into four groups and exposed to different chemical solutions (Distilled water, Listerine Original alcoholic mouthwash, Listerine Zero alcohol mouth wash, Ethanol 26.9%) twice daily for 60 seconds each according to manufacturer's instructions to measure the amount of force degradation in different time intervals. These elastomeric chains were incubated in covered glass containers at 37C? for the entire testing period.The results of the present study showed that the elastomeric chains were greatly affected by time, the majority of force loss occurred after the first 24hr. then followed by a less steep gradient for the rest of the working period.We can conclude that alcoholic mouth wash (Listerine Original) causes an increase in force degradation of all types of elastomeric chains while alcohol free mouth wash (Listerine Zero) causes less force degradation of all types of elastomeric chains, additionally closed configuration elastomeric chains has the least percentage of force degradation than other configurations of elastomeric chains.

الحركة الوحشية للطاحن العلوي الاول باستخدام انواع مختلفة من الاجهزة مسبقة الصنع : دراسة مختبرية مقارنة Distal Movement of Maxillary First Molar Using Different Types of Ready Made Appliances : An In Vitro Comparative Study

اسم المؤلف: ليث عمر المولى
اسم المشرف: هند طاهر جرجيس
الموضوع العام: طب الاسنان
السنة: 2014
الموضوع الدقيق: تقويم الاسنان
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Maxillary molar distalization is an important method for correcting class II molar relationship.The important thing in the use the distalizing appliances is to reduce the patient cooperation with minimizing the effects of distalizing appliances on the anchoring teeth.Aims : The aim of this study is to compare three different intra - maxillary molar distalization devices with different designs , force direction. Other aims are to compare the effect of these devices on first permanent molars in mesiodistal , buccopalatal, rotational aspects. It aims also to compare the effect of these devices on the first premolar ( which is a part of anchoring system ).Materials and Methods : The samples consisted of three groups; Frog appliance, K - Loop spring and Multidistalizing arch on typodont simulation system (Ormaco). Upper typodont arch of class II division I was used.Pre and postoperative digital images were taken and analysed using AutoCAD software for each group, Six parameters was measured and compared ; first molar ( vertical change ,tipping change ,rotation, distalization rate) and first premolar (vertical change ,tipping change).A significant value of 0.05 was determined.Results : The results of present study showed that the multidistalizing arch gave rise a significant distal tipping, extrusion, distopalatal rotation of first molar and gave rise the highest mean value of first molar distalization rate. Also, gave rise a significant distal tipping and extrusion of first premolar.Frog appliance showed the lowest mean value of molar distalization rate ,distal tipping and rotation , in comparison with Multidistalizing arch (MDA) and K - Loop spring. Also, these parameters ranged between the highest and lowest mean value in extrusion of first molar , first premolar vertical change , Also showed lowest mean of distal tipping of first premolar than Multidistalizing arch (MDA).K - Loop spring ranged between the highest and lowest mean value distalization rate , distal tipping of first molar. Also, showed the lowest mean value in extrusion of first molar and extrusion of first premolar and rotation of first molar.However, The K - Loop spring show mesial tipping of first premolar in comparisom with (MDA) and Frog appliance that show distal tipping of first premolar.Conclusions : It is concluded that the three methods are effective in molar distalization. The best method of first molar distalization ranged between the K - Loop spring and Frog appliance. Consequently the two methods showed good amount of molar distalization with minimal effects on first molar and first premolar.