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تحضير و تشخيص مشتقات البنزمايد ثنائية و ثلاثية التعويض كميزوجينات ذات نهايات منتفخة == Synthesis and characterization of di - and tri - substituted benzamide derivatives as bis - swallow - tailed mesogens

Author name: دنيا مالك هادي
Supervisor name: نسرين رحيم جبر
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Baghdad

الترسيب الكهربائي للانديوم,القصدير,الانتيمون على النحاس من السائل الايوني == Indium, Tin and Antimony electro deposition from ionic liquid on copper substrate

Author name: ازل اسامة احمد
Supervisor name: هادي محمد علي عبود
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Baghdad

تحضير بعض مشتقات املاح البريدين كمضادات لتاكل الفولاذ الطري في حامض الكبريتيك == Synthesis of some N - pyridinium salt derivatives as corrosion inhibitors for mild steel in sulfuric acid

Author name: احمد عماد جواد
Supervisor name: مهدي صالح شهاب
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Baghdad

تخليق وتشخيص بعض مشتقات الحوامض الامينية ودراسة الفعالية المضادة للبكتريا == Synthesis and Characterization of Some Amino Acid Derivatives and Studying Its Antibacterial Activity

تقييم التاثير المنخفض لفرط سكر الدم لمستخلصات وريقات نخيل القنطار ضد مرض السكر == Evaluation of Hypoglycemic effect of Phoenix dactylifera Ganthar Leaflets Extracts Against Diabetes Dise

Author name: رنين سالم سوادي
Supervisor name: عباس دواس مطر المالكي
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

دور العناصر النزره والاسمة في خصوبة نساء متلازمة تكيس المبايض في الناصرية == The role of trace and toxic elements in productive of female with polycystic ovary syndrome in AL - Nasiriyah

Author name: نبا نعمة حميد
Supervisor name: ساجد حسن كزار | ايناس صالح الخياط
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Dhi Qar

تخليق وتشخيص ودراسة مضادات الاكسدة لبعض المشتقات الجديدة (لداي هايدروبرميدين/ثايون) == Synthesis, characterization and Antioxidant Study of some new Dihydropyrimidine - 2 - (1H) - ones /thion derivative

Author name: نور ريسان علي
Supervisor name: محمود شاكر مكطوف
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Dhi Qar

تخليق وتشخيص ودراسة الفعالية البايولوجية لبعض مشتقات الموناسترول ثايونس الجديدة == SYNTHESIS AND CHARACTRIZAITION AND STUDY BIOLOGICAL ACTIVITY OF SOME NEW MONASTROL THIONES DERIVITATIVE

Author name: احمد احسان فليح حسن
Supervisor name: محمود شاكر مكطوف
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Dhi Qar

تحضير وتشخيص بعض مركبات ازو - ازوميثين واستخدامها في استخلاص ايون الكاديميوم الثنائي بطريقة استخلاص نقطة الغيمة == Synthesis and characterization of some Azo - Azomethine compounds and using them in could - point extraction of Cadmium Ion

Author name: ميعاد نكاد عوض
Supervisor name: ساهر عبد الرضا علي
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Dhi Qar

تحضير وتشخيص مشتقات جديدة ين 4,3,1 - اوكسادايازول و 4,2,1 ترايازول ومعقداتها مع بعض ايونات العناصر الانتقالية == Preparation and Characterization of new Derivatives of 1,3,4 - Oxadiazol and 1,2,4 - Triazole and its complexities with some transition metal ions

Author name: امنة نعيم هليل الركابي
Supervisor name: ابراهيم عبود فليفل
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Dhi Qar

تحضير وتشخيص بعض مركبات البنزوثايوزول ودراسة صفاتها البلورية السائلة == Synthesis and Characterization of some Benzothiazole compounds and study their Liquid Crystalline properties

Author name: سجى عبد الحسين طالب
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

تحضير وتشخيص ودراسة الفعالية البيولوجية لبعض المركبات العضوية والعضوية لفلزية الجديدة المتضمنة النتروجين

Author name: زينب كاظم الخزرجي
Supervisor name: بشرى كامل السلمي | عادل علي الفريجي
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

تحضير وتشخيص ودراسة الفعالية البايولوجية لبعض مشتقات الثايزولدين الجديدة == Synthesis, Characterization and Biological Activity Study of Some New Thiazolidine Derivatives

Author name: ايات ناجـــي حســــــن عــلي
Supervisor name: داود سالم عبد
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

تحضير وتشخيص ودراسة طيفية وكهربائية لبعض معقدات الفثالوسيانين واشباهها وتشويبها بمشوبات عضوية ولاعضوية == Synthesis, Spectroscopic and electriecal studies for some Phthalocyaninen and Semiphthalocyanine complex and their doping with organic and inorganic dopants

Author name: ايات جودت كاظم مجيد
Supervisor name: نزار عبد الامير حسين
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

تحضير وتشخيص ودراسة الفعالية البايولوجية وكمضادات اكسدة لبعض مشتقات الغابابنتين ومعقداتها مع [Zn(II), Cu(II)] == Synthesis, Characterization, Biological Activities and Antioxidant Study of Gabapentin Derivatives and their complexes with [Cu(II), Zn(II)]

Author name: اسامة حسن سالم البدران
Supervisor name: ظافر محمد حسين المظف | لي حسين الموالي
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

تخليق انابيب ثنائي اوكسيد التيتانيوم و جسيمات الفضة النانوية وتطبيقها في التحرر الدوائي و الفعالية الحيوية == Synthesis of Titanuim dioxid and Silver Nanoparticles and their applications in Drud Release and Bioactivity

Author name: احمد مكي صداع
Supervisor name: زينب طه ياسين
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

تحضير وتشخيص دايمرات متناظرة وغير متناظرة ودراسة صفاتها البلورية السائلة == Synthesis and Characterization of Symmetric and non - Symmetric Dimers and Study their Liquid Crystalline properties

Author name: ابتهال حميد شهيب
Supervisor name: عهود جبارعبيد الحمداني
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Basrah

دراسة العلاقة بين هرمون مخزون المبيض واضطرابات الغدة الدرقية لدى النساء والمصابات بمتلازمة تكيس المبيض في بغداد == A case study of the relationship between AMH and thyroid disorders in female patients with poly ovarian syndrome in Baghdad

Author name: سماح مشعان عبد ا لله
Supervisor name: نوال محمد جواد الشماع
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
University: University of Baghdad
Language: English
University location: Baghdad

عزل وتشخيص وتعيين السليلوز و النانوسليلوز واللكنين لسيقان نبات زهرة النيل في العراق == Isolation, characterization, and determination of cellulose, nanocellulose and lignin of dried stems of water hyacinth in Iraq

Author name: ياسر فتحي محمود
Supervisor name: محمد حسن عبد اللطيف
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Baghdad

تحضير وتشخيص مركبات حلقية غير متجانسة من مشتقات الفانيلين == Synthesis and Characterization of Heterocyclic Compounds from Vanillin Derivatives

Author name: مراد كدر مناحي نويف
Supervisor name: خضير جواد كاظم
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Babylon

دراسة نمذجة جزيئية لعقار الجنتاميسين وبعض مشتقاته الجديدة == Molecular Modeling Study of Gentamicin Drug and Some of Its New Deriv

Author name: مروة كامل جليل احمد
Supervisor name: عباس عبد علي دريع الصالحي
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Babylon

دراسة ازالة صبغة السلستين الزرقاء من محاليلها المائيه بالامتزاز على الاوكسيد المركب NiO - MgO النقي والمشوب == Study The Removal of Celestine Blue Dye from their Aqueous solutions by adsorption over mixed oxides NiO - MgO pure and doped

Author name: هدى سلام غني محمد السامرائي
Supervisor name: صادق جعفر باقر
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Babylon

طريقة طيفية جديدة لتقدير ايونات النحاس II والحديد III باستخدام المركبات الدوائية الاموكسيسلين صوديوم والسيفيكزيم ثلاثي الهيدرات == New Spectrophotometric Method for the Determination of Cu(II) and Fe(III) using Drug Compounds(Amoxicillin - Sodium and Cefixime Trihydrate)

Author name: علي سعدون ناجي دحام
Supervisor name: عباس نور الشريفي
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: English
University location: Babylon
Abstract: This thesis consists of three methods : | Describes three simple and sensitive methods for the determination of copper (II), iron (III) ions and Cefixime trihydrate drug. | The first method based on determination of copper ion in aqueous so-lution, in its pure form, pharmaceutical preparations and in fungicide sam-ples, by oxidizing phenol group in Amoxicillin drug in oxidative coupling reactions, coupled of two molecules of Amoxicillin, these oxidized by cop-per (II) ion as oxidized agent in alkaline medium pH 11.5 to give a violet coloured product, soluble in water, has maximum absorption at wave-length (540) nm at 30 ᵒC. Beer's law was obeyed between (5-32) μg.ml-1, a molar absorptivity (5× 104) L.mol-1cm-1, Sandell's sensitivity (0.12)μg cm-2, the LOD was (0.29) μg.ml-1 , LOQ was (0.97) μg.ml-1. | The second method includes determination of iron (III) depends on reduced iron (III) to iron (II) by Cefixime trihydrate as reducing agent, the iron (II) react with three molecules bipyridyl to form red coloured product complex, soluble in distilled water in acidic medium PH 3.3 that has max-imum absorption at wavelength 520 nm. Beer's law was obeyed between (0.5-11) μg.ml-1, a molar absorptivity (1.02 × 104) L.mol-1.cm-1, Sandell's sensitivity (5.49 ×10-3) μg.cm-2, the LOD was (0.013) μg.ml-1, LOQ was (0.045) μg.ml-1. This method was applied successfully for the determina-tion of iron (III) in pure state and in pharmaceutical formulations (Tablets, Syrup), the analytical results were compared with the standard method was used for determination of iron (III), | The third method has been described a reversible determination of Cefixime trihydrate based on the same above second method, the iron (III) as oxidizing agent in acidic medium, under the same optimum conditions at wavelength (520) nm. Beer's law was obeyed between (1-18) μg.ml-1, a | molar absorptivity (5.55 × 103) L.mol-1.cm-1, Sandell's sensitivity (1.01×10-2) μg.cm-2, the LOD was (0.032) μg.ml-1, LOQ was (0.106) μg.ml-1. This method was applied successfully for the determination of (CEFI) in phar-maceutical formulations (Tablets and Syrup). | Evaluating the proposed methods results by using F and t- test. It was found that results experimental F and t value at 95% confidence level did not exceed the critical values. This means the proposed methods have no different significally in accuracy and precision with standard method. The effect of interference ions (Mn(II), Co(II), Ni(II), Zn(II), Ag(II), Hg(I), Cd(II), pb(II)) on copper(II), and iron(III) also has been studied.

تخليق وتشخيص والتقييم البايولوجي لبعض مشتقات السبروفلوكساسين == SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME CIPROFLOXACIN DERIVATIVES

Author name: نادية صادق مجيد البوعبيد
Supervisor name: ناظر نجم عبد الله
General topic: Chemistry
Specific topic: Chemistry
Degree: Doctorate
Language: English
University location: Babylon
Abstract: الفصل الاول : يصف الاهمية الدوائية لدواء السبروفلوكساسين ومشتقاته كدواء مضاد للالتهابات ونبذه تاريخية لكل ما يتعلق بتحضير الامايدات والاسترات والثايواستر والهيدرازايد بالاضافه الى تفاعل سازوكي بطريقة حديثة وذلك باستخدام طريقة التشعيع باستعمال المايكرويف (MWI) في التحضيروتم التطرق ايضا الى اهم التطبيقات البايولوجية. | الفصل الثاني : تطرق بالتفصيل الى الجزء العملي وطرق التحضير العامة وكذلك تضمن التحليل لاطياف الاشعة تحت الحمراء FT-IR واطياف الرنين النووي المغناطيسي للبروتون 1 1H-NMR ونظيرالكاربون13 13C-NMR اضافة الى التحليل الدقيق للعناصر (CHNS). | الفصل الثالث : تطرق بالتفصيل الى النتائج ومناقشتها وتفسيرات الاطياف كما تطرق الفصل الى الفعالية البايولوجية للمركبات المحضرة من خلال ست مسارات : - | المسار الاول : يضم تحضير مشتقات استرية للسبروفلوكساسين (2-6) عن طريق تفاعل السبروفلوكساسين مع خمس انواع من الكحولات الاليفاتية بالتعاقب (الميثانول, الايثانول, البروبانول | البيوتانول والبنتانول) بوجود حامض الكبرتيك المركز كعامل مساعد في التفاعل وباستخدام تقنية MWI) ). مخطط (1) | المسار الثاني : تضمن تحضير مشتقات الثايواستر للسبروفلوكاسين (7-11)من تفاعل السبروفلوكاسين مع مركبات عديدة للثايو بوجود DMF كمذيب وباستعمال تقنية MWI . مخطط (2 ) | المسار الثالث : تضمن تحضير مشتقات الهيدرازايد للسبروفلوكاسين (12-15) من تفاعل السبروفلوكاسين مع مشتقات الهيدرازين بعد تحضير الاستر(3) كمركب وسطي في التفاعل باستخدام تقنية (MWI). مخطط (3 ) | المسار الرابع : يضم تحضير مشتقات امايدية للسبروفلوكساسين (16-29) باستعمال تقنية (MWI) مع مشتقات الامين الاليفاتية والاروماتية بعد تكوين مشتق الاستر (3) كمركب وسطي في التفاعل. مخطط (4 ) | المسار الخامس : تطرق الى تخليق مشتقات جديده لدواء السبروفلوكاسين من تفاعل ازدواج سازوكي (30-43) والتي تم تحضيرها من تفاعل مشتق السبروفلوكاسين (17) مع مختلف حوامض البورون الاروماتية المعوضة وباستعمال palladium-tetrakis(triphenyl phosphine) كعامل مساعد بواسطة التفاعل النيوكليوفليي البسيط . مخطط ( 5 ) | ان جميع هذه المركبات قد تم تحليلها وتشخيصها بواسطة طيف الاشعة تحت الحمراء وطيف الرنين النووي المغناطيسي للبروتون 1 ونظير الكاربون 13 وكذلك بواسطة التحليل الدقيق للعناصر (CHNS) كما وتم متابعة سير التفاعلات الكيميائية باستعمال تقنية TLC بوجود نوعين من المذيبات Hexane : Ethyl acetate) ) بنسبه (2 : 3) باستعمال جهاز الUV عند الطول الموجي 254 نانوميتر. | المسارالسادس : تم قياس الفعالية البايولوجية للمركبات المحضره على اربعة انواع من البكتريا المرضية (staphylococas aurans and Grantice tella adiacens) gram positive and (E.coli, protens mirabilis) gram negative | واظهرت جميع المشتقات فعالية بايولوجية عالية تجاه هذه الانواع من البكتريا تفوق فعالية دواء السبروفلوكساسين الاصلي. | == First chapter described the pharmacological importance of ciprofloxacin drug and its derivatives as anti-inflammatory drug and the literature review about the most significant process of synthesis amides, esters, carbothioate and carbohydrazide as well as Suzuki reaction by new method using microwave irradiation technique, Some of the biological applications of these compounds were studied | Second chapter described all compounds (2-43) in details the experimental work and the general procedures of preparation as well as including the analysis of FT-IR, 1H-MMR, 13C-NMR and C.H.N.S analysis. | Third chapter described in details the results and discussion for all prepared derivatives as well as explaining the result of biological activity and included six paths : | First path contains the synthesis of ester Ciprofloxacin derivatives (2-6) by reacting Ciprofloxacin drug with five types of aliphatic alcohols (Methanol, Ethanol, Propanol, Butanol and Pentanol) respectively in the presence of sulphuric acid as a catalyst by using MWI. Scheme (1) | Second path contains the preparation of carbothioate derivatives of Ciprofloxacin (7-11) by reaction Ciprofloxacin with various thio compounds in the presence of DMF as solvent by using MWI. Scheme(2) | Third path includes the preparation of carbohydrazide derivatives of Ciprofloxacin (12-15) by reacting Ciprofloxacin with different substituted | hydrazine compounds after synthesis of Ciprofloxacin derivatives (3) as an intermediate compound in this reaction by using MWI. Scheme (3) | Fourth path contains synthesis of amide Ciprofloxacin derivatives (16-29) by using microwave irradiation with aliphatic and aromatic amine derivatives after forming ester derivative (3) as intermediate compound in this reaction. Scheme (4) | Fifth path describes the synthesis of new Ciprofloxacin derivatives by Suzuki coupling reaction (30-43) during treatment ciprofloxacin derivative (17) with different substituted aryl boronic acid by using pd(pph3)4 palladium-tetrakis(triphenyl phosphine) as a catalyst via oxidation, transformation and reduction steps. Scheme (5) | All these synthesized compounds(2-43) were analyzed by the FT-IR, 1H-NMR, 13C-NMR spectra and (C.H.N.S) analysis as well as the follow up the progress of chemical reactions by using TLC technique. | Sixth path included the assay of biological activity of the synthesized compounds against four types of bacteria (staphylococcus aureus, Granutice tella adiacens) gram positive and (E. coli, Proteus mirabilis) gram negative the results exhibited excellent biological activity of all these synthesized compounds of these microorganisms much higher than the effectiveness of Ciprofloxacin drug. |

تحضير و تشخيص و تقييم الفعالية الحيوية لبعض المركبات الحلقية الغير متجانسة الجديدة لمشتق5.5 ثنائي مثيل ايميدازولدين دايون == Synthesis,Characterization and Biological activity of Some New Heterocyclic Compounds For 5,5 - dimethylimidazolidine - dione

Author name: محمد رضا عبود الحيدري
Supervisor name: شيرين رضراسول
General topic: Chemistry
Specific topic: Chemistry
Degree: Master
Language: Arabic
University location: Babylon
Abstract: The work reported in this thesis involves synthesis of 26 new heterocyclic compounds of 5,5-dimethyl imidazolidinedione.All the prepared compounds have been studied phesical properties and identified by using( FT-IR, 1H-NMR ( Schemes 1, 2 and 3 summarize the preparation steps. | The ester derivatives of the 5,5-diethylhydantoin have been prepared M1 compound has highest percentage yield(Scheme 1). | The carboxylic acid derivatives of imidazolidandione M2 have been synthesized either by hydrolysis of M1 using hydrochloric acid or by alkylation of the nitrogen of M by fusing it with bromo acetic acid in basic medium. The reaction of M2 with thionyl chloride gave compound M3 as shown in (Scheme1). | Synthesis of hippuric acid derivative M4 have been done by the reaction of M3 with glycine in the presence of 10% NaOH, followed by a cyclization reaction to M4 with different substituted aldehydes in the presence of acetic anhydride/acetic acid to get 1,3-oxazole in M5 and M6 derivatives as shown in (Scheme1). | The synthesis of 1,3-imidazole M7 and M8 have been conducted using hydrazine 80% with 1,3-oxazole derivatives (M5 and M6) as shown in (Scheme2). | Synthesis of imidazole esters M9 and M10 by the reaction of M7 and M8 with ethylbromo acetate in basic media then used in reaction with hydrazine 80% to prepar M11 and M12 as shown in (Scheme 2) | Also, the M11 and M12 have been used to prepare two different types of derivatives as follows : - | Firstly;by treating with carbon disulfide in basic media and cyclization to prepare 1,3-oxadiazole derivatives substituted by thiol group M13 and M14. | Summary | II | Secondly;synthesis of triazole M15 and M16 from M11 and M12 by reaction with carbon disulfide in basic media followed by addition of hydrazine 80% as shown in (Scheme2). | On the other hand, synthesis of M17 and M18 by reacting of M5 and M6 with ethyl acetoacetate in basic medium as shown in (Scheme3). | The M17 and M18 used to prepare two different types of derivatives : Firstly; synthesis of pyrazole derivatives M19 and M20 by reaction of M17 and M18 with hydrazine hydrate 80% during ten hours. | Secondly; synthesis of hydrazide derivatives M21 and M22 by reaction M17 and M18 with hydrazine hydrate 80% during five hours as shown in (Scheme3). | Synthesis of new Schiff base derivatives M23 and M24 by addition new aldehyde p-bromobenzaldehyde and N,N-dimethylamino benzaldehyde to M21 and M22 and finally cyclization by acetic anhydride to prepared M25 and M26 as shown in (Scheme3). | For some prepared compounds M1-M26 the λexcitation, λemmition, intensity and absorbency at the same concentration were studied and quantum yields are calculated. | Also biological activity of some of the prepared compounds are studied by using two type of bacteria( Escherichia coli and Staphylococcus aureus) and most of them showed good antibacterial activity
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