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تقييم التاثيرات الفيزيولوجية لحوض ماء ال (CO2) على القدم السكري == Evaluation of physiological Effect of (CO2) Water bath on diabetic Foot

اسم المؤلف: غزوان رياض عبد الحمزة
اسم المشرف: حنان لؤي العمري
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الفسلجة
الدرجة: ماجستير
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: تعتبر قرحة القدم السكرية واحدة من اكثر المضاعفات التي تقلق المصابين بمرض السكري غير المتحكم والمسيطر علية. حيث تعتبركواحدة من اهم ومن اكثر المضاعفات الشائعة والمعروفة لدى المصابين بهذا المرض وهي سبب رئيسي للاعاقة والمراضة والوفيات بين المرضى المصابين بمرض السكري ، وقد تم تقدير ان 15٪ من جميع الاشخاص المصابين بالسكري سيصابون بقرحة في بعض مراحل حياتهم العمرية . ان الهدف من هذة الدراسة هو تقييم تاثير علاج الماء المشبع بغازثاني اكسيد الكربون على قرحة القدم مرضى السكري ومقارنتها مع المرضى الذين يعانون من قرحة القدم السكري الذين يتعالجون بالعلاج التقليدي ، ان منهاج العمل لهذة الدراسة هو اخذ مئة مريض مصابين بمرض السكري ويعانون من قرحة القدم السكري (متوسط العمر 51.6 سنة ± 8.43 سنة ؛بتصنيف 59 ذكر و41 انثى) انقسما الى مجموعتين ،المجموعة الاولى بالعلاج التقليدي بالضمادات (التنظيف ، والكحول والشاش) والمضادات الحيوية ، في حين ان مجموعة الثانية هي ايضا بالعلاج التقليدي بالضمادات (التنظيف ، والكحول والشاش) والمضادات الحيوية مع اضافة العلاج بالماء المشبع بغاز ثاني اكسيد الكربون.تم اجراء هذه الدراسة في خلال فترة سبعة اشهرعلى الذين تم علاجهم باستخدام العلاج التقليدي كمجموعة والمجموعة الثانية باستخدام العلاج التقليدي بالضافة الى الماء المشبع بغاز ثاني اكسيد الكربون بواقع 4 ايام من بداية سبتمبر/ ايلول عام 2017 الى مارس / اذار 2018 في مركز القدم السكري Diabetic Foot Center في مدينة الصدر الطبية التابعة الى دائرة الصحة في النجف / وزارة الصحة العراقية ، في مدينة النجف / العراق . خلال الدراسة تم قياس مؤشر الكاحل العضدية ودراسة الدوبلر للشرايين ايضا ،و تم التقييم الكلي لحجم ولون والاحساس في منطقة التقرحية في قدم المريض المصاب بالسكري والمقارنة بينو وبين المريض المصاب بتقرح القدم السكري من المجموعة الثانية.واظهرت النتائج تحسن تدفق الدم الى القدم المصابة التي اظهرتها في اختلافات كبيرة في مؤشر الكاحل العضدية وفحص الدوبلر في مجموعة العلاج بالماء المشبع بغاز ثاني اكسيد الكربون قبل وبعد العلاج ثاني اكسيد الكربون. وكذلك تحسين الاحساس وحجم ولون المنطقة التقرحية. فاعلية هذه الطريقة في علاج قرحة القدم السكرية ويشير الى انها فائدة محتملة كشكل من اشكال العلاج الطبيعي في علاج قرحة القدم المصابة بالسكري والتي اظهرت ان هناك تحسنا كبيرا في مؤشر الكاحل العضدي وقياس فحص الدوبلر في المريض مع قرحة القدم السكري بعد العلاج الماء المشبع بغاز ثاني اكسيد الكربون ، كما اظهر تحسن كبير في حجم القرحة ، لون القرحة والاحساس بعد العلاج ثاني اكسيد الكربون في مرضى القدم السكري بعد العلاج ثاني اكسيد الكربون. تهدف هذه الدراسة الى تقييم تاثير علاج الماء المشبع بغاز ثاني اكسيد الكربون في تقييم تدفق الدم من خلال مراقبة مؤشر العضد في الكاحل وفحص الدوبلر وكذلك لتقييم تاثير علاج الماء المشبع بغاز ثاني اكسيد الكربون في فحص شفاء الجروح عن طريق دراسة حجم ولون القرحة والاحساس في مرضى السكري المصابين بتقرح القدم | Diabetic foot ulcer is considered one of the most anxious complications associated with uncontrolled diabetes mellitus. Foot ulcers are one of the most feared andxcommon complications ofxdiabetes. They are a majorxcause of disability, morbidity, and mortality amongxdiabetic patients, and it has been estimatedxthat 15% of all people withxdiabetes will have an ulcer at some stagexof their life, The aim is to evaluate the effect of carbon dioxide therapy on patients with diabetic foot ulcer and compare it with patients had diabetic foot ulcer on traditional therapy, Patients & Methods handred patients with diabetic foot ulcer (mean age 51.6 ± 8.43 years; 59 male and 41 femal) we divided into two groups , traditional treatment by dressings (cleaning, alcohol and gauze) and antibiotics, while carbon dioxide therapy group who were treated using a traditional treatment and carbon dioxide therapy this study was done in period of seven moths 4 days per start from Sumptember 2017 to March 2018 at Diabetic Foot Centre in Al Sadier Medical City / Najaf Directorat of Health, in Al - Najaf city. Ankle brachial index and Doppler were measured also, the size, color and sensation of the ulcerative area were all evaluated and compared between two groups. The results showed improvement of blood flow to the affected foot that shown in significant differences in Ankle brachial index and Doppler study in carbon dioxide group therapy pre and post carbon dioxide therapy (P <0.001). As well as improvement in the sensation, size and color of the ulcerative area. The effectiveness of this method in the treatment of diabetic foot ulcer and indicates it is potential utility as a form of physiotherapy in the treatment of diabetic foot ulcer which was showed there is significant improvement in Ankle brachial index and Doppler measurement in patient with diabetic foot ulcer after carbon dioxide therapy, It also was showed an significant improvement in the size of ulcer, color of ulcer and sensation after carbon dioxide therapy in diabetic foot patient after carbon dioxide therapy. The aims of this study is to evaluate the effect of carbon dioxide water bath therapy in assessing blood flow by monitoring ankle brachial index and Doppler study inxdiabetic foot ulcer patient and also To evaluate the effect of carbon dioxide water bath therapy in assaying wound healing by monitoring size and color of ulcer and the sensation in diabetic foot ulcer patient.

انتشار كتلة العضلة غير الطبيعي لدى المرضى العراقيين المصابين بفصال الركبة وتاثيرها على نوعية الحياة == Prevalence of Abnormal Muscle Mass in Iraqi Patients With Knee Osteoarthritis and its Effect on Quality of Life

اسم المؤلف: رغد دريد يحيى
اسم المشرف: فائق ايشو كوريال
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Age - related osteoarthritis is characterized by degradation of articular cartilage and substantial loss of matrix, as a consequence of senescence; Intra - articular cell senescence and cartilage matrix degradation, extraarticular loss of skeletal muscle mass and deteriorated proprioception contribute to development of osteoarthritis. Age - related degenerative loss of skeletal muscle mass and strength is referred to as Sarcopenia, skeletal muscle mass is the metabolically active body component, however, fat massis metabolically inactive, so that the changes of skeletal muscle mass and fat mass with aging can be one of the most relevant biomarkers of senescence.Aim of the study This study was conduc ted to assess the prevalence of abnormal muscle mass (sarcopenia) in Iraqi patients with knee osteoarthritis and to evaluate the effect of sarcopenia on knee osteoarthritis patient's quality of life.Patients and methods This was a cross sectional study conducted at Baghdad Teaching Hospital, Unit of Rheumatology during the period from august 2017 to the end of June 2018, a total of 150 Iraqi females aged 50 years old and older with knee osteoarthritis. Plain X - rays of the weight bearing bilateral knee joints were obtained from the anterio - posterior and lateral aspects with 30º of knee flexion, quality of life and disease impact assessment was done by using Western Ontario and McMaster Universities Osteoarthritis Index, Physical activity measurement was done by using The leisure - time Physical Activity Index. Assessment of sarcopenia was done by using a dual energy x - ray absorptiometry scan for the body composition analysis, fat mass, lean mass, and bone mineral density. Diagnosis of sarcopenia was made via measuring skeletal mass index which defined as appendicular skeletal muscle mass /height m², cut off point ≤ 5.6 kg/m² for female and handgrip strength was measured using a Dynamometer, cut off point < 20 kg. Body mass index (BMI) was measured. History of sociodemographic and medications including steroid and NSAIDs were taken.Results : The current study revealed that 14 (9.3%) of Iraqi women with knee osteoarthritis had sarcopenia. BMI appear to significantly predict sarcopenia (negative correlation), since the OR less than 1.0, both T score and Z predict sarcopenia (negative correlation) and T score appear to predict sarcopenia better than Z score (since the OR is lower in T score compared to Z score), LM and FMI negatively correlated with sarcopenia, gripe strength negatively correlated with sarcopenia.Age, menopausal duration, and sarcopenia appear to directly correlate with osteoporosis, while BMI, LM, FMI, negatively correlated with osteoporosis. Patients with sarcopenia had 7 folds increase risk of having osteoporosis. There was no significant association between WOMAC scoring (quality of life indicator) and sarcopenia and osteoporosis in women with knee osteoarthritis.

دراسة المؤشر ات الحيوية للخلايا الجذعية السرطانية FOXM1, TAZ, EpCAM,CD47 في ما يتعلق بالمعلمات النسيجية لسرطان الثدي

اسم المؤلف: رفاه محمد جعفر الخطیب
اسم المشرف: سالم رشید حمودي العبیدي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض النسيجية
الدرجة: دكتوراه
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

سرطان الثدي لدى النساء العراقيات في العقد الخامس من العمر == Iraqi Female Breast Cancer In Their Fifth Decade (Retrospective Study

اسم المؤلف: ضحى محمد كاسب
اسم المشرف: منور عبد الاله النقاش
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الاشعة العلاجية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الكلمات الدلالية:
  • Iraqi breast cancer
  • molecular classification
  • Luminal A like
  • DFS
الصفحات الاولى:
المستخلص: the United States, breast cancer remains the most frequent cancer in women and the second most frequent cause of cancer death.Breast cancer incidence generally increases with age. Age of the patients is an important factor both for the occurrence and management of the disease Objective : The aim of this study to assess Iraqi female breast cancer patients’ clinical profile in their fifth decade, Evaluate patients’ molecular profile and 5years DFS.Patients and methods This is aretrospective study was conducted in Baghdad oncology teaching hospital fromJanuary12012 toDecember122016, carried on979breast cancer female patients 285patients of them ranging between(40to49)years with their histopathology reports and immunohistochemichal (IHC) results including ER, PgR, HER2/neu The patients in this study underwent surgical intervention either by a biopsy or mastectomy with axillary clearance, and the formalin - fixed paraffin - embedded tissue blocks were sent to the hospital’s laboratory for H&E and IHC.ResultsThe mean age 45 years, the highest incidence of breast cancer among patients in 5th (40 - 49 years) and 6th (50 - 59 years) decades of life(29% and 28%)respectively , while the lowest incidence in 80 years and more female. Regarding the stage ;stage II and III were the most common stages at diagnosis (40.8% and 39.5%) respectively ,while CIS is the lowest stage(3.1%).XIILuminal A like were 124 patients (58.5%), Luminal B like were 30 patients (14.2%), Triple negative were 29 patients (13.7%) and HER2 overexpressed were 29 patients (13.7%). The highest frequency was seen among patients with Luminal A like followed by Luminal B - like . Denovo metastatic patients occupy only 6.7% from all studied group. DFS was 48 months with (95% CI : 41.4 - 54.5 months).ConclusionsHighest prevelance of breast cancer was seen in 5thand 6th decades. Stage II breast cancer is the most common stage at diagnosis. Luminal A was the most common molecular subtype of the breast cancer patients in the studied group.Her2overexpressed and triple negative were the lowest with the same percentage. Most patient s in our study were overweight or obese.Median DFS was 48 months.

التاثيرات الصحية لداء الفقار المقسط على جودة الحياة والاداء الوظيفي للمرضى العراقيين == Health - Related Quality of Life and Work Outcome in Iraqi Patients with Ankylosing Spondylitis

اسم المؤلف: نورا صباح مهدي
اسم المشرف: نزار عبد اللطيف جاسم
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Ankylosing Spondylitis (AS) is a chronic inflammatory rheumatic disease, mainly affecting the axial skeleton, and less frequently the peripheral joints, entheses as well as other extra - articular organs such as the eyes, heart and lungs. AS has a considerable effect on the individual’s healthrelated quality of life. Work disabled patients with AS experience a significantly reduced quality of life.Objective : To evaluate health - related quality of life and factors influencing it in patients with Ankylosing Spondylitis, as well as, to assess work outcome and its correlation with quality of life in AS patients.Patients and Methods : A case - control study was conducted at the Rheumatology Unit in Baghdad Teaching Hospital during the period from August 2017 to March 2018. A total of 168 patients (151 male : 17 female) with Ankylosing Spondylitis were enrolled in the study, all of them fulfilled the modified New York criteria for Ankylosing Spondylitis, and Assessment of Spondyloarthritis International Society (ASAS) classification criteria for axial spondyloarthropathy, and compared with 169 healthy controls (149 male : 20 female) matched for age and sex. Socio - demographic and clinical data of the patients and controls were collected. Health - related quality of life and work outcome were evaluated by the medical outcome survey short form - 36 (SF - 36) and work productivity and activity impairment - specific health problem (WPAI - SHP) scores respectively.Results : the mean age of the studied groups was 37.4 ± 9.4 years and 36.9 ± 9.5 years in Ankylosing Spondylitis and control groups, respectively. The median disease duration in AS patients was 11.3 ± 7.6. The quality of life in Ankylosing Spondylitis patients on all the scales of the short form 36 (SF - 36), was significantly worse than in the control group. Mental health quality of life was mostly affected than physical health overall. Role - physical was the most affected subscale of the short form - 36 (SF - 36). Male gender, smoking,fatigue, bath Ankylosing Spondylitis functional index (BASFI), treatment with biologics (anti - tumor necrosis factor) were significantly associated with the components of physical & mental health - related quality of life. Of 168 patients, 126 were employed (75%). Patients with Ankylosing Spondylitis reported work absenteeism loss, work productivity loss, overall work impairment, and daily activity impairment of 9.19%, 48.17%, 36.19%, 50.82% respectively. Work productivity and activity impairment - specific health problem (WPAI - SHP) summary scores were significantly correlated with all scores of quality of life (short form - 36).Conclusions : Ankylosing Spondylitis has negative impact on patients’ healthrelated quality of life, affecting both physical & mental health. Male gender, smoking, fatigue, poor functional status, treatment with biologics were the most associated factors with better or worse quality of life in patients with Ankylosing Spondylitis. AS has a significant effect on working conditions, quality of life has a direct relationship with a patient’s ability to work.

تقييم نوعية الحياة لدى المرضى العراقيين المصابين بمرض بهجت وعلاقتها مع فاعلية المرض == Quality of life assessment in Iraqi patients with Behçet’s disease and its relationship with disease activity

اسم المؤلف: میس عجیل جبار
اسم المشرف: فائق ايشو كوريال
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Behçet’s disease is a multisystem inflammatory disorder characterized by recurrent exacerbations affecting mucocutaneous tissues, eyes, blood vessels, and several other tissues. Among them, vascular and nervous system involvement are the most common causes of mortality in Behçet’s disease. The previous studies have shown that Quality of Life in patients with Behçet disease was negatively affected by the disease.Aim of the study : To evaluate Quality of Life in patients with Behçet’s disease compared with healthy controls, To assess the correlation of Quality of Life with organ involvements of Behçet’s disease and To assess the effect of demographic and clinical features of Behçet’s disease on Quality of Life. Patients and Methods : A case - control study was conducted at the Rheumatology Unit of Baghdad Teaching Hospital in Medical City from July 2017 to January 2018 . A total of seventy - one consecutive patients (45 male : 26 female) were classified as Behçet’s disease by fulfilling the International Study Group criteria 1990 for Behçet’s disease and compared with seventy - one healthy controls (45 male : 26 female) matched for age and gender. After acquiring their consent, findings were gathered using a preconstructed data collection sheet for patients and controls that evaluate Age, gender, smoking status, disease duration, age at disease onset, Behçet’s disease organ involvements were reported. Disease activity was assessed using Behçet's disease current activity form and health - related quality - of - life was evaluated using The Short Form - 36 (SF - 36) .Results : All the components of Short Form - 36 (SF - 36) , it’s summary scores and Total Short Form - 36 (Total SF - 36) score was significantly lower ( p - value <0.001 ) in patients compared to control . Patients with eye involvement had significantly higher Physical functioning (p - value = 0.023), role - physical ( p - value <0.001), and bodily pain (p - value <0.010) subscores when compared to those without eye involvement. Patients with skin involvement did not show a significant impairment in all SF - 36 subscales when compared to those without skin involvement. Behçet's disease Patients with articular involvement, Physical functioning (p - value = 0.027), bodily pain (p - value <0.001), and general health (p - value = 0.018) subscores are significantly impaired when compared to those without articular involvement .Behçet’s disease patients with myalgia, Physical functioning (p - value = 0.001), bodily pain (p - value = 0.018), and vitality (p - value = 0.038) subscores are significantly impaired when compared to those without myalgia. patients with Central nervous system involvement, physical functioning (p - value = 0.006), rolephysical (p - value <0.001), bodily pain (p - value = 0.001) , general health (p - value = 0.001) and vitality (p - value = 0.042) subscores are significantly impaired when compared to those without Central nervous system involvement. There are certain demographic and treatment modalities had a significant positive impact on Total SF - 36 score : Male gender (p - value = 0.020) , use of cyclosporine (p - value = 0.043 ), use of infliximab (p - value = 0.001), and use of adalimumab (p - value = 0.001) . While others had a significant negative impact on Total SF - 36 score : Disease duration (pvalue = 0.019) , Behçet’s Disease Current Activity Form (BDCAF) (p - value = 0.043 ), and use of Mycophenolate mofetil (p - value = 0.043 ).

تقييم نسبة خلايا الدم المتعادلة الى الخلايا اللمفاوية وعرض توزيع الصفائح الدموية كعلامات التهابية في عينة من المرضى العراقيين المصابين بمتلازمة الالم الليفي العضلي == Evaluation of blood neutrophil - lymphocyte ratio and platelet distribution width as inflammatory markers in a sample of Iraqi patients with fibromyalgia

اسم المؤلف: فادية علي شعلان
اسم المشرف: زياد شفيق الراوي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Fibromyalgia syndrome is a diminished quality of life related to generalized body pain with physical and psychological symptoms that occurs in the absence of a clear pathologic cause. Neutrophil to lymphocyte ratio is a simple parameter to assess easily the inflammatory status of a subjects. Platelet distribution width is a regular parameter in blood routine examination which reflects variation of platelet size distribution. Mean platelet volume is a part of the complete blood count test and correlates with the platelets function and activation.Objective : To evaluate Neutrophil to lymphocyte ratio, Platelet distribution width and Mean platelet volume in patients with Fibromyalgia as an inflammatory markers.Patients and Methods : This case - controlled study was conducted at Baghdad Teaching Hospital, Unit of Rheumatology, from July 2017 till November 2017. A total of 100 Iraqi patients with Fibromyalgia diagnosed according to 2012 Canadian Guidelines in addition to 50 healthy subjects worked as a control group were recruited. Data were collected using a paper clinical research form through interview and questionnaires. It consisted of two parts : the first part for the demographic data and full history, the second part laboratory data when the samples collected and sent for laboratories to obtain Platelet distribution width and Mean platelet volume while Neutrophil/lymphocyte ratio was calculated manually.Results : The neutrophil to lymphocyte ratio was significantly higher among patients with fibromyalgia (2.18) compared to healthy controls (1.92) (p =0.033). The Mean platelet volume was significantly higher in patients with fibromyalgia (8.3) compared to healthy controls (8) (p =0.045). In contrast, the Platelet distribution width was significantly lower among patients with fibromyalgia (16.7) compared to healthy controls (17) (p=0.01). No statistically significant differences had been found in demographic variables. None of the tested parameters qualified as an acceptable test for predicting a diagnosis of fibromyalgia, since the Receiver operating characteristic area associated with any of them did not reach the minimum value of (0.65).Conclusions : The Neutrophil to lymphocyte ratio is significantly higher in fibromyalgia patients compared to the healthy controls. The Mean platelet volume is significantly higher in the patients compared to the controls. The Platelet distribution width was significantly lower among the patients compared to the healthy controls. None of these tested parameters qualified as an acceptable test for predicting a diagnosis of Fibromyalgia.

العلاقة بين الخصائص السريرية وبروز القرص القطني وانتقامة المثبت بفحص الرنين المغناطيسي == The Relationship between Clinical Features and Magnetic Resonance Imaging Proven Lumbar Disc Bulging and Herniation

اسم المؤلف: ابان ناظم علي
اسم المشرف: خضير زغير معيوف البدري
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Lumbar disc herniation is one of the commonest causes of low backpain. The Magnetic resonance imaging is a gold standard noninvasiveinvestigation for viewing lumbar anatomy and physiology in great details.Obesity is strongly linked to biomechanical changes that damage thespine and contribute to a range of spinal diseases including intervertebraldisc herniation.Aim of the studyTo evaluate the effects of body mass index and waist to hip ratio on thepresence, extent and severity of lumbar disc bulging and herniation as wellas to determine the relationship between clinical features and magneticresonance imaging proven lumbar disc bulging and herniation.Patients and methodsA cross - sectional study was conducted at Baghdad Teaching Hospital,Rheumatology Unit during the period from October 2017 to May 2018. Atotal of 100 patients with lumbar disc bulging and herniation proven by MRIwere included in this study. The patients were examined neurologically andtheir body mass index was calculated as well as the waist to hip ratio.ResultsThe magnetic resonance imaging findings demonstrated that (72%) ofthe studied group had disc bulge, (13%) had disc protrusion and (15%) haddisc extrusion with no cases of disc sequestration. Multiple discinvolvements were seen in (73%) of those patients. The correlation betweenbody mass index and the total disc bulge/extrusion score was statisticallysignificant. There was a significant association between neurological deficitand body mass index as well as between straight leg raising test, femoralVIstretch test, neurological deficit and the waist to hip ratio. On the other hand,there was no significant association between clinical features and nerve root compression for patients with both normal body mass index as well as overweight and obese ones, although the frequency of patients with positive clinical findings was higher in patients with nerve root compression but the difference did not reach the significant level (P - value >0.05). The sensitivity of straight leg raising test, femoral stretch test and crossed straight leg raising test were (39.6%), (25.3%) and (6.6%) respectively.ConclusionsThere is an increase in the likelihood of having lumbar disc herniation and its global severity in overweight and obese patients. The clinical findings were more severe in overweight and obese patients especially in patients with central obesity. There was no significant association between the clinical features and the nerve root compression in patients with both normal body mass index as well as overweight and obese ones. The type of disc displacement associated poorly with clinical signs and symptoms as well as with the obesity.

الارتباط بين الموجات فوق الصوتية للوريد البابي الكبدي والنتائج التنظيرية في دوالي المرئ == Correlation between portal vein Doppler ultrasound and endoscopic findings in esophageal varices

اسم المؤلف: اسراء مزاحم ذاكر
اسم المشرف: ليث احمد خلف
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الاشعة التشخيصية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: خلفية عن الموضوع : دوالي المريء ، وهو احد المضاعفات الرئيسية لتليف الكبد ، يمكن ان يؤدي الى تهيدد للحياة نتيجة نزيف الجهاز الهضمي.الهدف من البحث : تقييم الاداة التشخيصية للكشف عن دوبلر الوريد البابي (سرعة ، قطر ، مؤشر الازدحام ، وحجم الطحال) للتنبؤ بدوالي المريء.الطرائق : تم تضمين 51 مريضا بالغا يعانون من تليف الكبد في الدراسة. خضع جميع الاشخاص الى الموجات فوق الصوتية في البطن وتنظير المريء. تضمنت مؤشرات الوريد البابي التي تمت دراستها مؤشر الاحتقان الكبدي ، وقطر الوريد البابي ، سرعة الوريد البابي وحجم الطحال. تم حساب حساسيتها ونوعيتها والقيم التنبؤية باستخدام التنظير المريء كمعيار ذهبيالنتائج : كانت الارتباط بين سرعة الوريد البابي ومؤشر الاحتقان الكبدي مع وجود دوالي المريء ذات دلالة احصائية (قيمة p <0.05). كان سرعة الوريد البابي اعلى حساسية 92.7 ٪ للكشف عن وجود دوالي المريء. وكان مؤشر الاحتقان الكبدي اعلى خصوصية من 99 ٪ واعلى قيمة تنبؤية ايجابية من 99 ٪. كانت القيمة التنبؤية السلبية اعلى سرعة الوريد البابي بنسبة 66.7 ٪.استنتاج : يمكن ان يكون دوبلر بالموجات فوق الصوتية بديلا سهلا ، رخيصا وامنا . حيث لا يتوفر تنظير المريء . مؤشرات دوالي الوريد البوابي مفيدة للكشف عن دوالي المريء وافضل مؤشرات الدوبلر سرعة الوريد البابي ومؤشر الاحتقان الكبدي ، في حين ان قطر الوريد البابي قد يكون لها قيمة محدودة للتنبؤ بدوالي المريء | Background : Esophageal varices, a major complication of liver cirrhosis, can lead to life threatening gastrointestinal bleeding.Objective : Evaluate the diagnostic utility of portal vein Doppler findings (velocity, diameter, congestion index ) and spleen size to predict esophageal varices.Methods : A cross sectional study of 51 adult patients with cirrhosis were included in the study. All of them underwent an abdominal ultrasound and esophageal endoscopy. The portal vein indices that were studied included hepatic congestion index, portal vein diameter portal vein velocity and splenic size. Their sensitivity, specificity and predictive values were calculated using esophageal endoscopy as a gold standard. Results : Association of PVV and HCI with presence of EV was statistically significant (p - value <0.05). PVV had the highest sensitivity 92.7% for detecting the presence of EV. HCI had the highest specificity of 99% and the highest positive predictive value of 99%. Negative predictive value was highest for PVV at 66.7%.Conclusion : Doppler Ultrasound can be an easy, cheap and safe alternative, where esophageal endoscopy is not available, available, for triaging patients for referral for esophageal endoscopy. Portal vein Doppler indices are useful for detecting esophageal varices, the best Doppler indices PVV and HCI, while PVD may have a limited value for predicting esophageal varices.

تاثير التجميد بالتزجيج وطرق الاذابة المختلفة على حيوية وسلامة الحامض النووي للنطف == The Effect Of Laser Thawing After Vitrification On Sperm Motility And DNA Integrity

اسم المؤلف: شذى صادق المراياتي
اسم المشرف: غسان ثابت سعيد
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الفسلجة
الدرجة: دكتوراه
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: ان التجميد بطريقة التزجيج تعتبر من طرق تجميد النطف البشرية وتعتمد على التجميد السريع للماء الى الحالة الزجاجية من خلال زيادة اللزوجة بدون تكوين بلورات داخلية (داخل الخلية). ان التجميد من الممكن ان يؤدي الى تاثيرات ضارة على تركيب ووظيفة النطف البشرية وان الاضرار الناتجة من التجميد من الممكن ان تؤثر على تركيب وسلامة الغشاء البلازمي. وان هذه الاضرار لا تقتصر على اضرار التجميد فقط بل تشمل ايضا على الاضرار الناتجة من عملية الاذابة بسبب اذابة او تبلور الثلج الناتج من التجميد. ان هذه العمليات ( التجميد والاذابة) من الممكن ان تؤثر سلامة الاحماض النووية وكذلك من الممكن ان تؤدي الى تغييرات في نواة النطف البشرية . ان التجميد قد يؤدي الى اجهاد تاكسدي للنطف البشرية كنتيجة الى انحلال الدهون التاكسدي وتقليل الية الدفاعية بواسطة الانزيمات المضادة للاكسدة. خلال عملية التجميد الخلايا والانسجة تخضع الى تغييرات كيميائية وفيزيائية . ان تاثير الليزر ومن خلال التحفيز الضوئي من الممكن ان يقاوم الاضرار الناتجة من التجميد للنطف البشرية وهذا من الممكن ان يؤدي الى تحسين نوعية النطف المجمدة وزيادة قابيلتها على الخصوبة. الهدف : دراسة تاثير الليزر كطريقة لاذابة النطف البشرية المجمدة وتاثيرها على سلامة الاحماض النووية والحركة مقابل الاذابة بدرجة حرارة الغرفة او عن طريق الحمام المائي. الموضوع والطرق : دراسة اجريت على 70 نموذج من النطف البشرية. كل نموذج قسم الى قسمين , قسم قد تم تحضيره بتقنية السباحة الى فوق والقسم الثاني بدون تحضير , وكل قسم قد قسم الى ثلاثة, جمدت, وتم اذابة كل جزء من النماذج بالليزر اوبدرجة حرارة الغرفة او بالحمام المائي بدرجة 37 درجة مئوية . تم دراسة سلامة الاحماض النووية وحركة النطف قبل وبعد التجميد , وكذلك قبل وبعد التحضير بتقنية السباحة الى فوق بطريقة الاكردين اونج (AOT) الحصول بالاعتماد على قياس المذنب (comet).النتائج : اظهرت النتائج ان الاذابة عن طريق الليزر لها تاثير معنوي (P<0.05 ) في تقليل تحطيم الاحماض النووية مع زيادة في الحركة الفعالة للنطف عند المقارنة مع الاذابة بدرجة حرارة الغرفة او بالحمام المائي.الاستنتاج : استنتجت هذه الدراسة ان تجميد الحيامن له اثار مؤذية تؤثر على سلامة الاحماض االنووية وحركة النطف البشرية. ان الاذابة بالليزر تحافظ على سلامة الاحماض النووية والحركة النشطة للنطف وان تقنية السباحة الى فوق كذلك تؤدي الى تنشيط النطف وتقليل تحطم الاحماض النووية. | Vitrification is a method of sperm freezing based on the rapid cooling of water to a glassy state through extreme elevation of viscosity without intracellular ice crystallization. Cryopreservation may lead to deleterious changes of sperm structure and function. Cryoinjury is not limited to the freezing process but may also occur during the thawing process as the ice melts or recrystallizes. It have been reported that cryopreservation/thawing significantly lead to alterations of sperm DNA integrity and could alter the quality of the spermatozoon’s nucleus. Cryopreservation induces oxidative stress in the spermatozoa due to increasing rate of lipid peroxidation and suppression of the antioxidant enzyme defense mechanism. These effects of cryopreservation lead to spermatozoa damage including nucleic acids. Subjects and methods : This prospective study carried on 70 cryopreserved semen samples. Each sample wasdivided into two parts, one part is unprepared and other part was prepared by swim - up technique and each part is divided into 3 parts, freezed and thawed by three methods of thawing by laser irradiation till melting for one part, and by room temperature and water bath at 37°C for the other two parts. The semen parameters were assessed by microscopical examination and the DNA integrity assessed by acridine orange test and comet assay before vitrification and after the three methods of thawing as well as before and after preparation. Result : The results of cryopreserved semen samples showed that laser irradiation thawing has a significant increase in sperm motility as well as a significant decreased DNA fragmentation (P < 0.05) versus room temperature and water bath thawing in addition sperm preparation by swim up method also lead to improve sperm motility and DNA integrity (P < 0.05).Conclusions : Vitrification has a deleterious effect on sperm DNA integrity and motility. Laser irradiation thawing methods of post freezing sperm improves post - thaw motility and DNA integrity. Sperm preparation by swim up technique for sperm preparation increasing motility and decrease DNA damage after thawing . The results of the acridine orange test and comet assay gave relatively similar predictive values for DNA fragmentation.

تواتر التدرن الكامن في المرضى المرشحين للعلاج البيولوجي في مستشفى بغداد التعليمي == The frequency of Latent tuberculosis infection in patients who are candidates for biological therapy in Baghdad Teaching hospital

اسم المؤلف: امل خالد علي
اسم المشرف: مصطفى نعمة عبد علي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الجهاز التنفسي
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Introduction : Tuberculosis remains one of the biggest global human killers accounting for 9.4 million new cases of active tuberculosis and 3 million tuberculosis - related deaths with an incidence of 140/100,000 inhabitants. More than 90% (up to 8 million) of total TB Tuberculosis cases occurring in developing countries and more than half of all deaths (2 million) occurring in Asia.Aim of the study : To assess the burden of latent TB in patients candidate for biological therapy.Patients and method : A descriptive cross sectional study conducted at Baghdad teaching hospital during the period from the 1st of April 2017 to the end of March 2018. A consecutive sampling included 150 respondents candidate for biological therapy were included in this study Results : The mean age of patients was 38.9±11.4 years. TST was positive in 23.3% of studied patients. Significant association between positive TST findings and middle age group (p=0.05). A significant association was observed between positive TST results and gender (p=0.001). Also significant association between prolonged duration of the disease, and positive TST.Conclusions : The TST were positive in about only one quarter of patients with chronic immunomediated diseases who are candidates for biological therapy, and significant associations were found between age group , and TST results.

نتائج الفحص بالرنين المغناطيسي لمرض سرطان المبايض بالارتباط مع الفحص النسيجي == Magnetic Resonance Imaging Findings Of Ovarian Malignancy In Correlation With Histopathology

اسم المؤلف: صبا قيس عيسى
اسم المشرف: خليل ابراهيم محسن
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الاشعة التشخيصية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: نبذة : التشخيص المبكر والعلاج من الاورام الخبيثة للمبيض مصحوبان بتنبؤات حياتية جيدة. التصوير بالرنين المغناطيسي له درجة عالية من الدقة في التصنيف المبكر لاورام المبيض.الهدف من الدراسة : لتحديد دقة التصوير بالرنين المغناطيسي في تشخيص الاورام الخبيثة في المبيض بالمقارنة مع التشريح المرضي كاختبار ذهبي.المرضى وطرق البحث : دراسة متابعة مستقبلية اجريت في وحدة التصوير بالرنين المغنطيسي في قسم الاشعة بمستشفى بغداد التعليمي في مجمع مدينة الطب في بغداد خلال الفترة من 1 فبراير 2017 الى 31 ديسمبر 2017 على عينة من 30 امراة مشتبهة بالاصابة بورم المبيض. تم فحص جميع المرضى مع التصوير بالرنين المغناطيسي الموزون الانتشار وتم جمع العينات لفحص التشريح المرضي.النتائج : كشف التصوير بالرنين المغنطيسي للنساء المصابات بورم خبيث في المبيض في 73.3٪ من النساء كما كشف تحليل الانسجة عن وجود ورم خبيث في المبيض في 73.3٪ من النساء. كانت نتائج صلاحية التصوير بالرنين المغنطيسي فيما يتعلق باورام المبيض الخبيثة حساسية (90.9٪) وخصوصية (75٪) وقيمة تنبؤيه موجبة (90.9٪) وقيمة تنبؤيه سالبة (75٪) ودقة (86.6٪). كانت قيمة القطع المناسبة لمعامل الانتشار الظاهر في التمايز بين الكتلة الضامة الخبيثة والحميدة 0.97 مع حساسية 100٪ وخصوصية 90.9٪.الاستنتاجات : ان التصوير بالرنين المغناطيسي الموزون الانتشار هو تقنية صالحة ويمكن الاعتماد عليها في تشخيص وتوصيف اورام المبيض. | Early diagnosis and treatment of adnexal malignancy is accompanied with good prognosis. The magnetic resonance imaging has high accuracy in early categorization of adnexal masses. Aim of study : To determine accuracy of magnetic resonance imaging in diagnosing ovarian malignancy in comparison to histopathology as golden test.Patients and methods : A prospective follow up study conducted in magnetic resonance imaging unit of Radiology Department in Baghdad Teaching Hospital in Baghdad Medical City Complex during the period from 1st of February, 2017 to 31st of December, 2017 on sample of 30 women with suspected adnexal masses. All patients were examined with diffusion - weighted magnetic resonance imaging and specimens were collected for histopathology examination.Results : The magnetic resonance imaging of women with adnexal mass revealed malignancy in (73.3%) of women and the histopathology revealed also malignancy in (73.3%) of women with adnexal mass. The validity results of magnetic resonance imaging regarding malignant adnexal mass were sensitivity (90.9%), specificity (75%), +ve predictive value (90.9%), - ve predictive value (75%) and accuracy (86.6%). The appropriate cut off value for apparent diffusion coefficient in differentiation between malignant and benign adnexal mass was 0.97 with (100%) sensitivity & 90.9% specificity.Conclusions : The diffusion - weighted magnetic resonance imaging among other MRI sequences that play valid and reliable role in diagnosis and characterization of adnexal masses. Keywords : Adnexal masses, Ovarian Malignancy Magnetic Resonance Imaging, Histopathology

نسبة الصفيحات الدموية الى الخلايا اللمفاوية ونسبة الخلايا اللمفاوية الى الخلايا الوحيدة لدى عينة من المرضى العراقيين المصابين بمرض بهجت == Platelet - Lymphocyte Ratio and Lymphocyte - Monocyte Ratio in a Sample of Iraqi Patients with Behçet’s Disease

اسم المؤلف: زهراء مصطفى كامل
اسم المشرف: فائق ايشو كوريال
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Behçet’s disease is a multi - systemic disorder, characterized bya remission and relapse , associated with a major morbidity and mortality.the principal pathological process is inflammation of blood vessels of allsizes and types (variable - vessel vasculitis).Platelet - lymphocyte ratio (PLR) and lymphocyte - monocyte ratio(LMR)regards simple, cheap parameters and was introduced as a novel marker todetermine inflammation in other diseases.ObjectiveTo evaluate the association between activity of Behçet’s disease withplatelet - lymphocyte and lymphocyte - monocyte ratio.Patients and MethodsThis case - control study conducted at Baghdad Teaching Hospital,Unit of Rheumatology from July 2017 to the end of February 2018. A total of 66 Iraqi patients who were diagnosed with Behçet's disease and met the inclusion criteria, and 66 apparently healthy individuals matched in age and sex as controls were enrolled. After acquiring their consent, data were collected using a pre - constructed data collection sheet, questionnaire including demographic and clinical data of the patients. Disease activity was assessed using Behçet's disease current activity form. Total White Blood Cells count and differential , C - reactive protein (CRP), erythrocytes sedimentation rate (ESR) were measured. platelet - lymphocyte and lymphocyte - monocyte ratio was calculated manually after obtaining the results from laboratory

الوضع الوبائي لمتلازمة العوز المناعي في العراق من 1990 - 2017 == Epidemiological Profile of HIV in Iraq From 1990 - 2017

اسم المؤلف: قيس عبد العزيز عبد المطلب
اسم المشرف: جواد كاظم الديوان
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الوبائيات التطبيقية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : HIV/acquired immune deficiency syndrome (HIV/AIDS) is a disease of far greater demographic diversity, affecting all ages, sexes, races, and income levels; involving multiple transmission risk behaviors; and having a broad geographic distribution worldwide.Globally, there are about 36.7 million people living with HIV, and 1.81 million new HIV infections occurred worldwide in 2016. There is insufficient epidemiological data on HIV infection in Iraq, so this study was conducted to estimate the prevalence, incidence and other epidemiological characteristics of HIV patients in Iraq.Methods : Descriptive cross sectional study was conducted by reviewing all records of HIV patients that retrieved from the Iraqi HIV Surveillance Center from1990 - 2017. Corresponding population data of Iraqi population was obtained from the Ministry of Health (MOH) - Directorate of Planning and Resource Development - Health and Vital Statistics Department. Results : The total number of the registered HIV patients in the Iraqi HIV Surveillance Center from 1990 - 2017 were 385 documented HIV cases. The prevalence and incidence of HIV infection in Iraq in 2017 were 0.66/ 100,000 populations and 0.24/100,000 population respectively, and they increased gradually over the last 27 years.The mean age of patients with HIV at time of detection was 31±12 years. Most of the patients aged 25 years and above that account for (86.8%).Males showed much higher percentage of HIV infection than females about 82%.Most of the cases concentrated in Baghdad governorate (123 cases) that represent 52.8%, followed by Erbil governorate (21,8.4%).Clinically suspecting HIV infection was the main route for detecting cases (22.07%), followed by blood donation (20%) of the cases.Sexual activities represent the major role of transmission about 57%, followed by blood and blood products consumption that represent 22.5%.Conclusions : The prevalence and incidence of HIV infection continue to rise over the last 27 years especially in the last five years. We recommend paying more attention to the control and prevention measures and enhancement of surveillance system.Keywords : HIV, Iraq, Epidemiology, ART.

الوفيات والمراضة الناتجة عن حالات التهاب المعدة والامعاء بين الاطفال دون سن الخمسة سنوات في بابل, 2007 - 2017 == THE MORTALITY and MORBIDITY of GASTROENTERITIS in UNDER 5 YEARS CHILDREN, BABYLON PROVNCE (2007?2017)

اسم المؤلف: رزاق هاشم محمد
اسم المشرف: علياء مكي حسن الصافي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الوبائيات التطبيقية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Diarrhea is one of the main causes of morbidity and mortality among children in developing countries. It was the second leading cause of death in children under five years, accounting for 9 % of all deaths among children under age 5 worldwide in 2015. Despite the availability of simple effective treatment, about 1,400 young children die each day which is equivalent to 526,000 children a year. According to Multiple Indicator Cluster Survey (MICS - 4), the incidence of diarrhea in Iraq was 15% .The objective of this study was to identify the incidence and deaths of gastroenteritis in children under five year in Babylon, 2007 - 2017.Methods : A descriptive cross - sectional study by reviewing all reported cases of gastroenteritis in hospitals and districts of Babylon province between 2007 - 2017.Incidence, mortality rate and case fatality rate (CFR) for <5 years population were calculated.Results : The mean of cases was 69,436 patients. A mean of outpatient was 60,243(86.8%) and 9,194(13.2%) were admitted cases. Male to female ratio was 1.1 : 1. Incidence of gastroenteritis was 237.8/1,000, the highest incidence was in 2012(302 /1,000), the lowest was in 2016(163/1,000), most deaths occur in children <1year (82.1%). CFR was (1.1/10,000), the highest case fatality rate was in2007 (3.9/10,000), there was no deaths in 2013 and 2015, therefore CFR was 0%.Proportional mortality rate (PMR) the mean was (0.3%); the highest PMR was in 2007 (0.8%), because there was no deaths in 2013 and 2015 PMR (0%).The incidence was higher in infants (477/1,000), than1 - <5 years (168.2/1,000) as means, which represented 2.8 times more in infants.Conclusion Diarrhea is still a major cause of morbidity and mortality in children under five years, which need to pay more attention for PHC efforts and community cooperation, improvements of living situations and encouragement of Breast feeding.Key words : Gastroenteritis, Babylon, Under 5 years children, Incidence, Case fatality rate, Proportional mortality rate.

دراسة العلاقه بين ارتفاع ضغط الدم الشرياني ومرض الانسداد الرئوي المزمن : دراسة مستندة الى المستشفى == Study of relation between systemic arterial hypertension and Chronic Obstructive Pulmonary Disease (Hospital Based Study

اسم المؤلف: زينب مهاوي هادي
اسم المشرف: محمد وهيب سلمان العبيدي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - الصدرية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: ان مرض الانسداد الرئوي المزمن هو سبب رئيسي للوفاة في جميع انحاء العالم . ويسبب العديد من الامراض خارج الرئه مثل داء السكري وامراض القلب والاوعيه الدموية .الهدف من الدراسة : لتقييم العلاقة المتبادلة بين مرض الانسداد الرئوي المزمن وارتفاع ضغط الدم الشرياني طريقــــــــــــــة البحث : اجريت دراسة مقطعيه على مئة مريض مشخص مسبقا بالانسداد الرئوي المزمن في ( مستشفى بغداد التعليمي ) و( مستشفى البصرة التعليمي ) وبعمر (35سنة واكثر. المرضى المصابون بامراض الاضطرابات التنفسية والقلبية والغدد الصماء الاخرى والذين لديهم تاريخ بارتفاع ضغط الدم المشخص قبل مرض الانسداد الرئوي تم استثنائهم من هذه الدراسة .النتائـــــــــــج : الدراسةاجريت ل( 100) مريض تم تشخيصهم مسبقا بــمرض الانسداد الرئوي المــــــــــــــــــــــــزمن حيث تبين ان (23 ) مريضا لديهم تاريخ ايجابي لارتفاع ضغط الدم الشرياني تم تشخيصهم بعد تطور مرض الانسداد الرئوي ؛ و(77) مريضا لديهم تاريخ سلبي لارتفاع ضغط الدم الشرياني.وبعد قياس ضغط الدم لذوي التاريخ السلبي السابق في ارتفاع ضغط الدم الشرياني وجد ان (14) لديهم ضغط دم طبيعي و( 36 ) مريضا لديهم ارتفاع ضغط الدم الشرياني للمرحلة الثانية .كانت هناك علاقة بارزة بين زيادة حدة مرض الانسداد الرئوي المزمن وزيادة القراءة لضغط الدم. الاستــنــــــــــــــــتاج : توجد علاقة بارزة بين مرض الانسداد الرئوي المزمن وتطور ارتفاع ضغط الدم الشرياني.الكلمات الدالة : ارتفاع ضغط الدم الشرياني , مرض الانسداد الرئوي المزمن , ضغط الدم . | Background : Chronic obstructive airway disease (COPD) is a leading cause of death worldwide. And it cause various extrapulmonary comorbidities as diabetes mellitus and cardiovascular diseases .Aim of Study : To assess the correlation between COPD and systemic arterial hypertension .Method : Cross sectional study was conducted on 100 patients diagnosed previously as COPD in Baghdad teaching hospital and Basrah teaching hospital (age≥35 year), Patients with other chronic respiratory disorder and cardiac and endocrine diseases and who had history of systemic arterial hypertension diagnosed before COPD were excluded from this study.Results : The study done on 100 patients diagnosed previously with COPD and found 23 patients had positive history of systemic arterial hypertension diagnosed after COPD developed and 77 patients had negative history of systemic arterial hypertension. and after measured blood pressure for the patients with negative previous history of systemic arterial hypertension 14 patients found having normal reading and 36 patients had stage 2 systemic arterial hypertension . There were significant association between increase in severity of COPD and increase in blood pressure reading.Conclusion : There is significant association between COPD and development of systemic hypertension.Keyword : Systemic arterial hypertension , Chronic obstructive pulmonary disease , blood pressure.

تقييم القصور الكلوي عند مرضى الانسداد الرئوي المزمن == Assessment of renal impairment in patients with chronic obstructive pulmonary disease

اسم المؤلف: مروة حمدي صالح
اسم المشرف: محمد وهيب سلمان العبيدي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الجهاز التنفسي
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الخلفية : مرض الانسداد الرئوي المزمن هو احد الاسباب الرئيسية للمراضة والوفيات في جميع انحاء العالم. من المتوقع ان يرتبط مرض الانسداد الرئوي المزمن بشكل كبير مع الاعتلال المشترك ، وقد افادت بعض الدراسات عن وجود اختلال كلوي في مرض الانسداد الرئوي المزمن في مجموعات مختارة من السكان.الهدف من الدراسة : لتقدير وتيرة الضعف الكلوي في عدد السكان من مرضى مرض الانسداد الرئوي المزمن.المرضى والطريقة : تم اجراء دراسة الحالة والضابطه للفتره من 1 يونيو 2017 حتى نهاية ابريل 2018 في مستشفى بغداد التعليمي. اجريت الدراسه على 100 شخص تم تصنيفهم الى مجموعتين : مجموعة مرض الانسداد الرئوي المزمن 50) مريضا يعانون من مرض الانسداد الرئوي المزمن) والمجموعة الضابطة (50 شخص دون مرض طبي مزمن)في البداية تم تاكيد تشخيص مرض الانسداد الرئوي المزمن وتقييمه للتدريج حسب التاريخ والفحص السريري وقياس التنفس. وقد تم تقدير معدل الترشيح الكبيبي وتم تصنيف المرضى وفقا لوظيفة الكلى لديهم وظيفة الكلى المستقرة ، اختلال وظائف الكلى المخفي واختلال وظائف الكلى العلني.النتائج : في مجموعة مرض الانسداد الرئوي المزمن ، كان متوسط قيمة نيتروجين اليوريا في الدم هي 44±19.4 ، وكان متوسط تركيز الكرياتينين في المصل 1.25 ± 0.53 وكان متوسط معدل الترشيح الكبيبي التقديري 67.6 ± 27.5 في المجموعه الضابطه, وان متوسط قيمة قيمة نيتروجين اليوريا في الدم هي 28.5± 5.8 ، وكان متوسط تركيز الكرياتينين في المصل 0.7 ± 0.1 وكان متوسط معدل الترشيح الكبيبي هو 97.3 ± 16.8 ( قيمة بي (<0,001) للجميع مقارنة مرض الانسداد الرئوي المزمن) . وجد ان معدلات انتشار كل من : وظيفة الكلى مستقرة ، خلل وظيفي كلوي مخفي واختلال وظيفي كلوي علني في مجموعة مرض الانسداد الرئوي المزمن هي 29 ٪ ، 16 ٪ و26 ٪ على التوالي. كان معدل الانتشار العام للضعف الكلوي ) معدل الترشيح الكبيبي اقل من 60مل /دقيقه/1.73م2 )يساوي 42٪ في مجموعة مرض الانسداد الرئوي المزمن و2 ٪ في المجموعة الضابطة ( قيمة بي<0.001) كان هنالك ارتباط احصائي لمرض الانسداد الرئوي المزمن مع كلا من الخلل وظيفي المخفي والعلني.للكلى.وقد وجد ان العمر ، وحالة التدخين العلبه/ العام ، ومدة المرض وانخفاض متوسط حجم الزفير القسري ارتبطت بشكل كبير مع الخلل الكلوي العلني.الاستنتاجات : هنالك ارتباط ملحوظ بين زيادة شدة مرض الانسداد الرئوي المزمن وارتفاع اليوريا في الدم، كرياتينين المصل ونقصان معدل الترشيح الكبيبي. | Background : Chronic obstructive pulmonary disease is a leading cause of death worldwide. COPD is expected to be significantly associated with comorbidity, and some studies have reported renal impairments in COPD subjects in selected populationsAim of the study : To estimate the frequency of renal impairment in a population of COPD patients Patients and method : A case control study carried out from the 1st of Jun. 2017 to the end of April 2018 in Baghdad teaching hospital. This study was conducted on 100 persons who were classified into two groups : case group (50 patients with COPD) and control group (50 persons healthy without chronic medical illness). First, the diagnosis of COPD was confirmed and evaluated for staging by history, clinical examination and spirometry. The glomerular filtration rate was estimated and the patients were categorized according to their renal function as having stable renal function, concealed renal dysfunction and overt renal dysfunction. Results : in the COPD group, the mean Blood Urea Nitrogen value was 44±19.4, the mean serum creatinine concentration was 1.25 ±0.53 and the mean estimated GFR was 67.6±27.5.In the control group, the mean BUN value was 28.5±5.8, the mean serum creatinine concentration was 0.7 ±0.1 and the mean estimated GFR was 97.3±16.8 (P<0.001) for all in comparison with the COPD). The prevalence of stable renal function, concealed renal dysfunction and overt renal dysfunction in COPD group was 29%, 16% and 26% respectively.The overall prevalence of renal impairment (GFR<60ml/min/1.73 m2) was 42% in COPD group and 2% in control group (P<0.001).Chronic obstructive pulmonary disease was significantly associated with both concealed and overt renal dysfunction. Age, Pack/year, duration of disease and decrease of FEV1 were significantly associated with overt renal dysfunction(GFR <60 ml/min/1.73 m2 with elevated blood urea and serum creatinine). Conclusions : there is significant association between increased COPD severity and elevated blood urea, serum creatinine and reduced glomerular filtration rate.

تقييم مستوى مصل حمض البوليك لمرض الانسداد الرئوي المزمن وعلاقته بشدة المرض وتكرار الانتكاسات : دراسة الحالات والشواهد == ASSESSMENT OF SERUM URIC ACID LEVEL IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ITS RELATION TO DISEASE SEVERITY AND EXACERBATION FREQUENCY (Case - Control Study

اسم المؤلف: الاء عبد الجبار
اسم المشرف: عدنان محمد الجبوري
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - الصدرية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Chronic obstructive pulmonary disease (COPD) is a major contributor to morbidity worldwide,and lead to damage lung tissue and so lead to reduce oxygen intake resulting in tissue hypoxia.Tissue hypoxia induces the degradation of adenosine triphosphate, resulting in production of serum uric acid.Identification of prognostic biomarker for COPD as serum uric acid(sUA) may aid in improving survival .Objective of the study : Evaluate role of hyperuricemia in disease severity and exacerbation frequency in COPD patients.Method : Case - control study was conducted from 1st of December 2017 to 1st of June 2018, on 80 subjects in Baghdad teaching hospital\medical city, 40 subjects with COPD, other 40 subjects are healthy persons consider as control, all >40 years old<70 .Serum uric acid level measured for all study sample.Excluded from this study those with Hx of Diabetes mellitus, Hypertension, Malignancy, Cardiac disease, Gout and persons on drugs affect sUA level.Results : The mean age for COPD was 61.9 while for control was 49.3 years.Serum utic acid higher in male than female in both group. In COPD cases there are higher level of serum uric acid compared to control and COPD patients had 3.16 time more risk to developed high serum uric acid than persons without disease also there was a significant statistical association between mean sUA and duration and degree of COPD (P value<0.05).Conclusion : Patients with COPD have higher serum uric acid level than control group, which tend to increase with increase in duration and severity of disease.

اهمية حالة استخدام جهاز الاستنشاق في السيطرة على الربو عند البالغين == Importance of inhaler device use in the control of asthma in adult

اسم المؤلف: حواء خالد علوان
اسم المشرف: مصطفى نعمة عبد علي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الجهاز التنفسي
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: الخلفية : يعتبر الربو من الامراض المزمنة العرضية للممرات الهوائية التي ينظر اليها بشكل افضل على انها متلازمة. في عام 1997 ، شمل المعهد الوطني للقلب والرئة والدم السمات التالية كجزء لا يتجزا من تعريف نوبات الربو المتكررة من الاعراض التنفسية ؛ انسداد تدفق الهواء المتغير الذي غالبا ما يكون قابلا للعكس ، اما بشكل عفوي او مع العلاج ؛ وجود تفاعل فرط مجرى الهواء. والاهم من ذلك ، التهاب المسالك الهوائية المزمن الذي تلعب فيه العديد من الخلايا والعناصر الخلوية دورا ، على وجه الخصوص ، الخلايا البدينة ، الحمضات ، اللمفاويات التائية ، الضامة ، العدلات ، والخلايا الظهارية.الهدف من الدراسة : لتقييم تقنية الاستنشاق المريض الربوالمرضى والطريقة : اجريت دراسة مقطعية مستعرضة في وحدة الامراض التنفسية في مستشفى بغداد التعليمي من 1 يوليو 2017 حتى نهاية فبراير 2018. واشتملت على 400 بالغ يعانون من الربو المستمر لمدة 6 اشهر على الاقل ، ووفقا للمبادرة العالمية لالمعايير الربو وادرجت في هذه الدراسة.النتائج : كانت اخطاء اعداد الجهاز موجودة في 47.2 ٪ من مرضى الربو ، وكان الفشل في الزفير قبل الاستنشاق في 80.2 ٪ من المرضى ، وزفير اثناء الاستنشاق كان موجودا في 10 ٪ من المرضى ، كان الوقت قصير للاستنشاق في 51.7 ٪ من المرضى ، والفشل في ان تحبس الانفاس لمدة 5 - 10 ثواني في 68٪ من المرضى ، ولم يكن الشطف بالماء بعد الاستنشاق موجودا في 85.5٪ من المرضى وكان التكرار اكثر من الموصى به في 22.8٪ من مرضى الربو . وجد ان هنالك ارتباط مهم للغاية بين المرضى الاصغر سنا ومسبار التركيز واجهزة الاستنشاق المقننة الجرعة.الاستنتاجات : هناك خطا في استخدام تقنية علاج الاستنشاق الربو. | Background : Asthma is a chronic, episodic disease of the airways that is best viewed as a syndrome. In 1997, the National Heart, Lung, and Blood Institute included the following features as integral to the definition of asthma recurrent episodes of respiratory symptoms; variable airflow obstruction that is often reversible, either spontaneously or with treatment; presence of airway hyper reactivity; and, importantly, chronic airway inflammation in which many cells and cellular elements play a role, in particular, mast cells, eosinophils, T lymphocytes, macrophages, neutrophils, and epithelial cells.Aim of the study : To assess the asthmatic patient's inhaler use technique,any error if present Any effect on asthma control from use technique error or type of inhaler.Patients and method : A cross sectional study conducted in consulting respiratory unit in Baghdad teaching hospital from the 1st of July 2017 to the end of February 2018. In which 400 adults with persistent asthma for at least 6 months duration, and according to the Global Initiative for Asthma criteria were included in this study. Results : Device preparing errors was present in 47.2% of asthmatic patients, failure to exhale before inhalation was present in 80.2% of patients, exhalation during inhalation was present in 10% of patients, short inhalation time was present in 51.7% of patients, failure to hold breath for 5 - 10 seconds in 68% of patients, not rinsing mouth with water after inhalation was present in 85.5% of patients and repetition more than recommended was present in 22.8% of asthmatic patients. Highly significant association between younger age patients and MDI & spacer,Conclusions : There is error in using the asthmatic inhalers treatment technique

اثار العلاج الاشعاعي على اختبار وظيفة الغدة الدرقية في سرطان الراس والعنق == Effects of Radiotherapy on Thyroid Function Test in Head and Neck Cancers

اسم المؤلف: زينة عماد عمران
اسم المشرف: خضير جاسم صبيح الرواق
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الاشعة العلاجية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Patients with head and neck cancers are often treated with external beam radiation therapy with or without surgery and / or chemotherapy. While radiation to the neck area may involve part or whole of thyroid gland ,the well - known side effect of hypothyroidism will subsequently ensue. Aim : to evaluate the risk of developing hypothyroidism after radiotherapy in patients with head & neck malignancies. Patients and methods : This is a prospective study of 40 patients of head and neck cancer, receiving radiotherapy in Baghdad center of radiotherapy from October 2017 to January 2018. TSH,T3 and T4 estimations were done at baseline and at 4 months following radiotherapy. Results : Before radiotherapy, all study patients showed normal T3, T4, and TSH levels with a mean of 1.88 ± 0.22, 123.92 ± 6.97, and 2.19 ± 0.67 respectively.After radiotherapy, all patients showed normal T3 and T4 with a mean of 1.8 ± 0.19 and 121.52 ± 8.86 respectively; while 12.5% of study patient showed elevated TSH level with a mean of 2.63 ± 1.44.The mean of TSH after radiotherapy was significantly higher than that before radiation (2.63 versus 2.19, P=0.044) while no statistical significant change in mean of T3 and T4 levels before and after radiation (P ≥ 0.05). The highest prevalence of elevated TSH level was seen in patients who had a history of surgery to head and neck (40%) with a significant association (P=0.047) between prevalence of elevated TSH level and past surgical history. There was no significant association (P ≥ 0.05) between prevalence of elevated TSH level and all other characteristics.Conclusions : The likelihood of thyroid dysfunction after radiation therapy is common and can initially manifested within 4 months and addition of surgery to radiation therapy can increase the risk of hypothyroidism by 40%.

المعارف والمواقف والممارسات المتعلقة باصابات وخز الابر بين العاملين في مجال الرعاية الصحية في بغداد == Knowledge, attitude and practices regarding needle stick injuries among health care workers in Baghdad

اسم المؤلف: ميس علاء الدين علي
اسم المشرف: سهير محمد محمود الجبوري
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: طب العائلة
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Needle stick injuries are serious occupational hazards in thetransmission of a variety of bloodborne diseases, more than twenty pathogens canbe transmitted through NSI including hepatitis B virus, hepatitis C virus, and humanimmunodeficiency virus (AIDS) among healthcare workers.Objective : Determine the prevalence of needle stick injuries among healthcareworkers and its predisposing factors. Assess the knowledge, attitude and practice ofhealth care workers towards needle stick injuries.Methods : Cross - sectional descriptive study, a convenient sample of 300 health careworkers were selected from various hospitals and primary healthcare centers inBaghdad, Iraq. Data were collected by an anonymous questionnaire from Februaryto May 2018. The collected data was analyzed by using statistical package for thesocial sciences (SPSS version 24).Results : Among the studied sample, there were 218 (72.7%) nurse and 82 (27.3%)laboratory technician. Prevalence of needle stick injury among the health workerswas found to be 38.7%, which was higher in nurses (40.8% of nurses) compared to32.9% of laboratory technicians. The highest number of needle stick injuriesoccurred by recapping of needles (43.8%) followed by injuries during handling(25%) and (23.2%) injuries while withdrawing a blood. A high proportion (84.33%)of health care workers whom sustained needle stick injury had reported their Injury.The mean score of knowledge, attitude, and practice were 8.21, 7.07 and 7.19respectively. Nurses scored better than laboratory technicians. A considerable percentage of the participants (88.33%) were immunized against HBV.Conclusions : The study showed a high prevalence of NSIs among health care workers. The score of knowledge was high, acceptable responses were obtained in most attitude and practice statements, except for recapping of needles statements.Key Words : needle stick injury, sharp injuries, universal precautions,

نتائج فحص الدوبلر الملون لامراض الكلى المنتيه المزمنة ومقارنتها بنتائج الفحص النسيجي الخلوي == Significance of Doppler indices finding in renal parenchymal disease Correlated with histopathological findings

اسم المؤلف: جنان حسين محمد
اسم المشرف: طالب الزيدي | ليث احمد خلف
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الاشعة التشخيصية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Renal Doppler ultrasound is increasingly used in assessment of renal parenchymal diseases as investigation and for evaluation of renovascular disease and allograft dysfunction. We compared intrarenal Doppler indices measurment to biopsy findings of Mesangial hypercellularity, Membranous glumerulopathy, Minimum change disease, Segmental glumeriolosclerosis, chronic glomerulonephritis, chronic rejection, acute rejection and interstitial nephritis in sample of 84 patient Patients and Method A study was conducted between 1st of Dec - 2016 to 1st of Oct - 2017 at radiological department of Al Shaheed Ghazi Hospital in the renal disease and transplantation center (Baghdad Medical city complex) on 84 patient who are suffering from renal disease manifestation in both native and transplanted kidneys. Doppler blood indices (Resistive index,Pulsatility index and Acceleration time) were measured at same day before renal biopsy. Renal biopsy finding and Doppler study indices were compared to asses' if there were a correlation between parenchymal renal changes and the Doppler indices changes. Aim of study to evaluate renal vascular Doppler indices (Resistive index , Pulsatility index and Acceleration time) as indicator of accuracy and prediction in renal parenchymal diseases,severity and grading Results RI, was significantly higher in patients group with renal diseases which in comparison to control group (0.70 ± 0.07vs. 0.55 ± 0.04),the accuracy was 72.9%,while P.I and AT show less significant changes P.I was (1.61 ± 0.25vs. 1.47 ± 0.06) and AT (0.086 ± 0.023vs. 0.024 ± 0.058). PI accuracy was 59.9 %and for AT was 54.2% .as consequence the mean value of RI was significantly differed among different renal pathologies (p=0.001) but the PI and AT were not differed significantly (p<0.05 for both).Conclusions Our results suggest that Renal Doppler indices ,as example (resistive index)was significantly increased in patients with renal parenchymal disease which confirmed by pathological examination and higher accuracy than other indices pulsatility index and acceleration time so we can use resistive index as good marker for parenchymal renal disorders while other indices can use as complimentary.

دراسة عن حالات التهاب الكبد الفيروسي ج عند مرضى التحال الدموي في وحدة غسيل الكلى في مستشفى بغداد التعليمي العراق == Hepatitis (C), virus infection among patients in Hemodialysis unit in Baghdad Teaching Hospital, Iraq, 2018

اسم المؤلف: عادل عبد عنبر
اسم المشرف: ايمان عدنان القصير
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: طب العائلة
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Background : Viral hepatitis C infection are important cause of morbidity and mortality in hemodialysis patients, and it's prevalence varies considerably among different areas of the world. Patients receiving maintenance hemodialysis are at high risk for acquiring hepatitis C virus infection than the general population. This study was conducted to estimate the prevalence rate and the possible associated factors responsible for hepatitis C viral infection among chronic hemodialysis patients in Baghdad.Iraq. 2018.Method : A cross - sectional study was carried out in hemodialysis unit in Baghdad Teaching Hospital for the period from 1st February to 30th April 2018. The study participants were all patients available during data collecting period. The participants were directly interviewed according to a special questionnaire designed for the purpose of the study. Data collected regarding patient's age, gender, duration of dialysis, number of sessions per week, history of blood transfusion, renal transplantation, previous surgery, history of tattoo, alcohol use, injecting drugs user, previous dialysis in another center, having diseases(Hypertension, Diabetes), and viral screen of all patients for hepatitis C and B viral infection. in addition of reviewing patient's medical records to confirm the laboratory results. Results : the total number of participants were 218 patients. The prevalence rate of Hepatitis C infection was 25.7%. male gender, age between 51 - 70 years, married and not worker patients were having higher prevalence rates of infection. Hemodialysis patients with diabetes mellitus and dental procedures were more prone to Hepatitis C infection while blood transfusion and frequency of transfusion was not a significant factor.Conclusion : High prevalence of Hepatitis C virus in hemodialysis patients in Baghdad teaching Hospital in Hemodialysis unit. The hepatitis C virus infection was significantly associated with Duration of dialysis, previous dialysis in another center, Diabetes mellitus, dental procedures and creatinine level. That need to follow the universal precaution to minimize nosocomial infection particularly at the hemodialysis unit.

عسر شحميات الدم اعتلال المفاصل الصدفي الفعال : دراسة حالة ضابط == Dyslipidemia in Active Psoriatic Arthropathy Case Control Study

اسم المؤلف: منار هشام صابر
اسم المشرف: عبد اللطيف جاسم
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - المفاصل
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Psoriasis is a chronic inflammatory skin condition characterized by scaly erythematous plaques on body surfaces. Psoriatic arthritis (PsA) is a unique, clinically heterogeneous type of inflammatory arthritis associated with skin psoriasis.Atherogenic dyslipidemia comprises a triad of increased blood concentrations of small, dense low‐density lipoprotein (LDL), decreased high‐density lipoprotein (HDL) particles, and increased triglycerides. Most recently, a relationship between psoriasis and increased risk of myocardial infarction, cerebrovascular disease, and peripheral vascular (cardiovascular) disease has been reported.Objectives : This study aimed to shed the light on dyslipidemia in psoriatic arthropathy patients and to determine any association between lipid abnormalities and disease activity.Patients and Methods : This study is a case control study which was conducted on 84 patients in Rheumatology and Dermatology department/ Baghdad Teaching hospital and 90 healthy controls for 8 months' period from August 2017 to April 2018. All patients with confirmed cases of Psoriatic arthritis according to CASPAR criteria. Data collected and analyzed according to patient history and Physical examination were including age, gender, body mass index, education level, occupation, smoking status, disease duration and disease activity score ,presence or history of dactylitis and enthesitis, history of diabetes, hypertension and hypercholesterolemia, cardiovascular diseases, and drug history of Disease - modifying antirheumatic drugs (DMARDs) and (anti - TNF agents), lipid lowering drug ,use of fish oil with its duration . Laboratory parameters were also taken including ESR and lipid profile.Results : Total number of the patient in this study was 84 and controls were ninety.The mean age was (42.6)years, 51% were male . There was no significant difference in age, gender and BMI between patients and control. Cholesterol, triglyceride and LDL were significantly higher in patients compared to controls p value <0.001 . There was no significant difference in the (Cholesterol, TG, HDL, LDL, and Atherogenic index) between low and moderate to high disease activity. There was direct significant correlation between cholesterol with TNFI duration p value (0.039 ) Conclusions Patients with psoriatic arthritis had elevated levels of cholesterol, TG, LDL and atherogenic index. There is a direct association between high level of cholesterol and the duration of TNF inhibitor treatment. The current study shows that, no relation between disease activity and lipidprofile abnormality

صلاحية معيار بروتين سي التفاعلي في تقييم شدة مرض الانسداد الرئوي المزمن : دراسة مستندة الى المستشفى == VALIDITY OF C - REACTIVE PROTEIN TITER IN ASSESSMENT OF SEVERITY CHRONIC OBSTRUCTIVE PULMONARY DISEASE (HOSPITAL STUDY BASE)

اسم المؤلف: رشا مناور عبد
اسم المشرف: محمد وهيب سلمان العبيدي
الموضوع العام: الطب
السنة: 2018
الموضوع الدقيق: الامراض - الصدرية
الدرجة: دبلوم عالي
الجامعة: جامعة بغداد - كلية الطب
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Chronic Obstructive Pulmonary Disease (COPD) : is one of the most important causes of morbidity and mortality all over the world.C - Reactive Protein (CRP) : a biomarker of systemic inflammation and as an indicator of malnutrition or severity of Chronic Obstructive Pulmonary Disease (COPD). An assessment the relationship between serum C - reactive protein (CRP) levels and well - known clinical parameters in severity of Chronic Obstructive Pulmonary Disease (COPD) considering the impact of smoking behavior.Aim of study : To evaluate the interrelationship between C - reactive protein and chronic obstructive pulmonary diseaseMethodsWe studied (69) diagnosed COPD patients according to GOLDstages all patients didspirometry, body mass index andserum CRP titer levels were investigated in diseased COPD patients.Results : Patients sample, 72.5% male and 27.5% female, the ratio (3 to 1) of COPD included (75.4%) had positive CRP and (24.6%) had negative CRP. CRP titer levels were higher in severe COPD patients and there’s inversely relationship between Body Mass and the incidence of the C - Reactive Protein. There’s close relationship between cigarette smoking, body mass and chronic obstructive pulmonary disease.Conclusion : The circulating levels of the inflammatory marker CRP are significantly elevated in patients with COPD, supporting the view that COPD is in part an inflammatory disorder. This risk increase with increased severity of disease and cigarette smoking and this level elevated with decreasing body mass index.
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