صلاحية معيار بروتين سي التفاعلي في تقييم شدة مرض الانسداد الرئوي المزمن : دراسة مستندة الى المستشفى == VALIDITY OF C - REACTIVE PROTEIN TITER IN ASSESSMENT OF SEVERITY CHRONIC OBSTRUCTIVE PULMONARY DISEASE (HOSPITAL STUDY BASE)
Author name:
رشا مناور عبد
Supervisor name:
محمد وهيب سلمان العبيدي
General topic:
Medicine
Specific topic:
Diseases - Thoracic
Degree:
Higher Diploma
University:
University of Baghdad - Faculty Of Medicine
Language:
English
University location:
Baghdad
First pages:
19T1476 - p.pdf
Abstract:
Chronic Obstructive Pulmonary Disease (COPD) : is one of the most important causes of morbidity and mortality all over the world.C - Reactive Protein (CRP) : a biomarker of systemic inflammation and as an indicator of malnutrition or severity of Chronic Obstructive Pulmonary Disease (COPD). An assessment the relationship between serum C - reactive protein (CRP) levels and well - known clinical parameters in severity of Chronic Obstructive Pulmonary Disease (COPD) considering the impact of smoking behavior.Aim of study : To evaluate the interrelationship between C - reactive protein and chronic obstructive pulmonary diseaseMethodsWe studied (69) diagnosed COPD patients according to GOLDstages all patients didspirometry, body mass index andserum CRP titer levels were investigated in diseased COPD patients.Results : Patients sample, 72.5% male and 27.5% female, the ratio (3 to 1) of COPD included (75.4%) had positive CRP and (24.6%) had negative CRP. CRP titer levels were higher in severe COPD patients and there’s inversely relationship between Body Mass and the incidence of the C - Reactive Protein. There’s close relationship between cigarette smoking, body mass and chronic obstructive pulmonary disease.Conclusion : The circulating levels of the inflammatory marker CRP are significantly elevated in patients with COPD, supporting the view that COPD is in part an inflammatory disorder. This risk increase with increased severity of disease and cigarette smoking and this level elevated with decreasing body mass index.
