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دور الانترلوكين RA - 1 والسكليروستين والخلية التائية المستجيبة CD4 في مصل مرضى التهاب المفاصل الرثوي == Role Of Serum IL - 1RA, Sclerostin And Effector T - Cell (CD4) In Rheumatoid Arthritis Patients

اسم المؤلف: سنن ثائر عبد الوهاب
اسم المشرف: حيدر صباح كاظم | علاء الدين مظفر زبير
الموضوع العام: الطب
السنة: 2016
الموضوع الدقيق: الاحياء المجهرية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: التهاب المفاصل الرثوي هو احد امراض المناعة الذاتية الاكثر شيوعا والذي يتميز بالتهاب المفاصل المزمن والذي يؤدي فيما بعد الى تدمير المفاصل.لا يزال مرض التهاب المفاصل الرثوي يعرف على انه سمة من التوسع في الغشاء الزليلي وارتشاح الخلايا الالتهابية اضافة الى | Rheumatoid arthritis (RA) is one of the most common systemic autoimmune diseases characterized by chronic joint inflammation and subsequent joint destruction. It is well known that RA is characterized by the expansion of the synovium and infiltration of the inflammatory cells coupled with destruction of adjacent articular cartilage and bone. This is strongly dependent on CD4 T cell. CD4 Cells stimulate monocytes, macrophages, synovial fibroblasts, and other cells to produce cytokines such as tumor necrosis factor - ? (TNF - ?), interleukin - 1 (IL - 1), IL - 6, IL - 15, IL - 17 and metalloproteinases that produce tissue damage. TNF is a major inflammatory cytokine contributing to the pathogenesis of RA, which provides rational for development of anti - TNF biological agents in the treatment of RA.Wnt pathway (a complex protein network) important in control of the bone formation through the regulation of osteoblast activity, and sclerostin is an important in the regulator of the Wnt pathway by blocking Wnt binding to its receptor and thereby inhibiting bone formation. Blockage of Wnt antagonists such as sclerostin will trigger repair or even healing of bone erosion.Recently have shown that IL - 1Ra has been given therapeutically in several experimental models of arthritis with weak effect in RA. This study planned to evaluate the frequencies of CD4+CD25+ Treg cells in Iraqi patients treated with RA under treatment with biological therapy (Etanercept). The level of serum sclerostin, serum level of IL - 1RA, and investigate the correlation between serum sclerostin and Treg expression. Correlate the level of serum sclerostin and Treg expression with disease activity by (CDAI or DAS28).This study was performed during the period from January 2016 to May 2016.The patients were attending the out patients' Clinic in Medical City/Baghdad Teaching hospital/Rheumatology Unit and the laboratory Enzyme Linked Immunosorbent Assay tests were done in Bio - technology center at the University of Al Nahrain, flow cytometery analysis was performed in the private laboratory (Al Rawabi Laboratory) at Yarmouk/Baghdad. Thirty patients and 30 apparently healthy control individuals were included in this study, Patients under treatment of etanercept.The diagnosis of RA patients has performed under the rheumatologist consultant at the consultation clinic of Baghdad Teaching Hospital of the medical city. Blood samples had taken from RA patients to measure Erythrocyte Sedimentation Rate, Complete Blood Picture, Rheumatoid Factor and High - Density Lipoprotein. Also, analyze the serum levels of Anti - Citrullinated Protein Antibodies and estimate the levels of sclerostin and IL - 1RAin patients and healthy individuals using Enzyme Linked Immunosorbent Assay test kits. CD4+CD25+ Treg cells had achieved by flow cytometery analysis.The results showed the reduction in Treg cells in patients (0.00264 ± 0.002) % under biological therapy than control group (0.026 ± 0.012) % with significant difference (p< 0.05). Also body mass index showed significant difference between patients (32.10 ± 5.81) kg/m2 and control group (28.84 ± 4.67) kg/m2 (p< 0.05). The results showed that sclerostin level higher in healthy (1.072 ± 0.59) ng/ml than patients (0.801 ± 0.28) ng/ml which showed significant difference (p<0.05). Furthermore IL - 1RA serum level was higher in healthy (0.979 ± 0.34) ng/L than patients (0.633 ± 0.35) ng/L with significant difference (p<0.05). Anti - Cyclic Citrullinated Peptide results showed non - significant difference between patients and healthy control. Treg cells is reduction in the patients with RA. Sclerostin and IL - 1RA levels are low in patients treated with etanercept.

دراسة جزيئية للاصابات بفايروس الحليمي البشري وفايروس سرطان الغدد اللبنية البشري في المريضات المجراة لهن عملية استئصال الرحم الكامل == Molecular Study Of Human Papilloma Virus And Human Mammary Tumor Virus Infections Of Patients With Total Hysterectomy

اسم المؤلف: سري ظافر داود العزيز
اسم المشرف: سعد حسن محمد علي | بسام شهاب احمد
الموضوع العام: الطب
السنة: 2015
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Theoretically , the origin & mode of in - utero transmission of high risk Human PapillomaVirus (HR - HPV) types could be acquired hematogenously, by semen at fertilization or as asending infection in the genital tract. Viral Oncogenes E6 and E7 have ability to altered the Cyclin D1,p21 and p27 protein levels. Worldwide, Human Mammary Tumor Virus(HMTV) infection been described in hormonal responsive tissues.This research work is to study viruses in relaition to endometrial carcinoma in Iraqi patients.Materials and MethodsA retrospective study envolved seventy(70) cases (158 samples) of endometrial and cervical tissues collected from teaching laboratories in Medical City, Al - Yarmok Teaching Hospital and private laboratories related to the period from 2012 to 2014. Sections were made and subjected to chromogenic in - situ hybridization technique to detect the presence of High risk (HR) HPV 16/18 DNA and HMTV integrated DNA (provirus) and immunohistochemical technique to detect the presence of Cyclin D1,P21and P27.Results : The most commonly affected age group was ? 60 year 60.0% in malignant endometrial tumors, 40 - 49 years 36.0% in non - malignant endometrial tumors. Adenocarcinoma was the only histopathological type among endometrial cancer (100%) and the majority have well differentiated grade (90.0% ),and have (70%) T1b/IB stage.Hight risk HPV16/18 expression was detected 33.3% of malignant endometrial tumors, 20% in non - malignant endometrial tumors, andSUMMARY26.7% in control group. The higher rates of expression of HPV in cervical lesions was 40%.Most HPV16/18 infections revealed in both sites (cervix and endomertium) have Punctate DNA pattern.Cyclin D1 expression was mostly in 43.3% of malignant endometrial tumors and 33.3% was in cervical lesions. The significant correlation between Cyclin D1 expression and HR - HPV16/18 infection was reported only in malignant endometrial tumors groups. The highest P21 expression was 40.0% in malignant endometrial tumors and 44.0% in cervical lesions that reveals a significant association between p21 expression and HR - HPV16/18 infection. The highest rates of P27 expression were noticed among non - malignant endometrial tumors 24.0% and 32.0% in cervical lesions.While significant association of P27 expression with HR - HPV16/18 infection was only found in the cervical lesions among malignant endometrial tumors group.The distribution of integrated HMTV genome detected by Chromogenic in - situ hybridaztion (CISH) in the endometrial tissues was 16.7% in malignant endometrial tumor , 8% in non - malignant endometrial tumors, and 13.3% in the control tissues group while in the cervical lesions HMTV was detected in 13.3%. Significant correlations were found between HMTV infection and Cyclin D1 expression in the cervical lesions among malignant endometrial tumors group and p21 expression in the malignant endometrial tumors.ConclusionsHR - HPV16/18 may be associated with initiation of endometrial carcinogenesis events as well as play a role in the progression of such malignant tumors in addition ,these viruses could ascendingly be transmitted from lower part(cervix) to the upper part of the genital tractSUMMARY(endometrium) in some way or other.Cyclin D1 ,P21,and p27 could have sharing in early events of tumorgenesis in endometrial carcinoma and a significant correlations of Cyclin D1 ,p21& p27 expressions with HPV infection was observed among study group.Althought a relating low rates of HMTV infection were detected among different endometrial as well as cervical lesion in this Iraqi study,it might mark or shade alight in the way for further researches in this field to exposure more aspects of this newly studied virus among other hormonal dependent malignancy

تقييم sFas ligand, sFas وcaspase - 3 في المرضى المصابين بمرض ابيضاض الدم النقياني المزمن == Assessment Of Soluble Fas, Soluble Fas Ligand And Caspase - 3 In Patients With Chronic Myeloid Leukemia

اسم المؤلف: سحر راضي ياسر
اسم المشرف: ميسون علي سليم | بسام فرنسيس متي
الموضوع العام: الطب
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: ابيضاض الدم النقياني المزمن هو اضطراب التكاثر النقي النسيلي للخلايا الجذعية ويتميز بواسطة فلادلفيا كروموسوم وهو انتقال متبادل بين كروموسوم 9 و22. الجين المسرطن المتحد الجديد المتولد على كروموسوم 22 كنتيجة للانتقال يسمى BCR - ABL gene. في اغلبية المرضى, هذ | Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of the haemopoietic stem cell, defined by the Philadelphia chromosome (Ph) - reciprocal translocation between chromosomes 9 and 22. The novel fusion oncogenes generated on chromosome 22 as a result of this translocation are called BCR - ABL gene. In the majority of patients, this oncogene transcribes a 210 - kDa constitutively active protein tyrosine kinase, often referred to as p210BCR - ABL, which is necessary for the transformation of the disease. The introduction of tyrosine kinase inhibitor (TKI) - imatinib mesylate (IM) - marked a major advance in CML treatment in terms of efficacy and tolerability and has now become the first line of therapy. In CML, besides genetic change during which a normal cell is transformed into a malignant one, evasion of apoptosis (programm cell death PCD) is one of the essential changes in a cell that cause malignant transformation. So ‘Evading apoptosis’ has been recognized as one of the six hallmarks of cancers, as reduced apoptosis or its resistance plays a vital role in carcinogenesis. Soluble receptors (sFas) that act as decoys, binding FasL and preventing association with transmembrane Fas. So production of sFas in tumor patients may be a key mechanism to inhibit Fas - mediated apoptosis. Soluble FasL competes with the membrane - bound counterpart; however, it can act even as an antagonist preventing apoptosis induction by the membrane integrated form of the ligand. Recently, caspase - 3 has been demonstrated to play an important role in determining the cellular sensitivity to diverse apoptotic stimuli, also it is involved in a number of non - apoptotic events. So the aims of the study were to estimate the level of serum sFas, sFas ligand & caspase - 3 in patients with chronic myeloid leukemia at time of diagnosis (newly diagnosed), then after receiving imatinib myselate treatment with optimal response and compare them with healthy control. It was a prospective study, included 56 Iraqi CML patients (25 were males and 31 were females with Age ranged from 15 - 78 years) attending to Baghdad teaching hospital/hematology department between November 2012 up to June 2013, were categorized by fluorescence in situ hybridization analysis (FISH) for Ph chromosome into two stages, newly diagnosed CML patients (FISH Ph cells result ? 90% ) not received any treatment and optimally treated (complete cytogenetic response (CCgR) = FISH Ph cells result < 1% or by major molecular response (MMoR) = BCR - ABL : ABL ?0.10% by International Scale, on RT - Q - PCR) with imatinib mesylate 400 mg/day at least 1 year. Then used an ELISA technique to assess serum level of sFas, sFas Ligand (sFasL) & Caspase - 3 for each patients of CML, and compared them with 28 apparently healthy volunteers used as control. The controls were age and sex matched with the patients, they were not taken medication and with no history of chronic illness and/or acute infection. As well as, they were nonsmoker and nondrinker. For patients the inclusion criteria including all patients were free of fever and other chronic illness such as diabetes mellitus, hypertension and infection; also they had no history of smoking and drinking of alcohol. And the exclusion criteria including patients suffering from any chronic, debilitating disease and other blood disorders were not taken.The observed results revealed the following : ? Patients were included in the study, male : female ratio was 0.8 : 1with mean age 42.6± 14.0.? The mean± SD serum of sFas levels (pg/ml) for the newly diagnosed and optimally responded of CML was 1163.6±231.5 and 1021.7±360.6 respectively.? The mean± SD serum of sFas Ligand levels (pg/ml) for the newly diagnosed and optimally responded of CML was 216.9±165.7 and 147.7±91 respectively. ? The median serum of Caspase - 3 (ng/ml) for the newly diagnosed and optimally treated cases was 0.421 and 0.361 respectively. ? The mean± SD serum of sFas and sFas Ligand levels (pg/ml) for the healthy group was 970.1±361.7, 152.5±98 consequently. The median serum of Caspase - 3 (ng/ml) for the healthy group was 0.314.? Serum sFas level was increased in newly diagnosed compare with optimal responder and healthy control group. Also serum sFas level in optimal responder group was increase when compared with healthy control group. The differences observed were no statistical significance (P=0.09).? Serum sFasL level was increased in newly diagnosed patients of CML when compared with optimal responder and healthy control group. But serum sFasL level in optimal responder group was decreased when compared with healthy control group. The differences observed were non statistical significance (P=0.07).? Serum Caspase - 3 level showed statistically significant (P ?0.001) increase in newly diagnosed when compared with healthy control group. While it was in optimal responder group was statistically increased (not significant P=0.13) when compared with healthy control group. And its level was increased in newly diagnosed compare with responder group which was statistically significant (P= 0.04).Finally, this study concluded that increase in sFas and sFas Ligand &Caspase - 3 in newly diagnosed CML patients compared with optimally and healthy control groups. Also concluded that Caspase - 3 was a good confirmed test to diagnose newly CML cases

دور بعض المؤشرات الالتهابية المختارة في البول وبروتينات خلية البودوسايت عند مرضى اعتلال الكلية السكري == The Role Of Selected Urinary Inflammatory Markers On Podocyte In Type 2 Diabetic Nephropathy

اسم المؤلف: داليا محمود خلف
اسم المشرف: رفيف صبيح الشوك | عصام نوري الكروي
الموضوع العام: الطب
السنة: 2017
الموضوع الدقيق: الاحياء المجهرية
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: اعتلال الكلية السكري هو السبب الرئيسي للمرض الكلوي المزمن وويرتبط ذلك مع زيادة وفيات مرضى القلب والاوعية الدموية. التعريف الكلاسيكي لاعتلال الكلية السكري هو زيادة افراز البروتين في البول. وتتميز المرحلة المبكرة للمرض عن طريق زيادة صغيرة في افراز الزلا | Diabetic nephropathy (DN) is the leading cause of chronic renal disease. It is associated with increased cardiovascular mortality. The DN has been classically defined as increased protein excretion in urine. Early stage is characterized by a small increase in urinary albumin excretion (UAE), also called microalbuminuria or incipient DN. More advanced disease is defined by the presence of macroalbuminuria or proteinuria. The latter is classically named overt DN.This study was planned with the aim of evaluate the levels of urinary Monocyte Chemoattractant Protein - 1(MCP - 1), interleukin (IL - 18), Osteopontin and Nephrin at diabetic nephropathy and its correlation with the parameters in Iraqi type 2 diabetic subjects and to explore the impact of albuminuria and duration of the diabetes on fine glomerular architecture using podocyte injury related marker (Nephrin) in urine. This may explore the more specific, and sensitive early biomarkers for nephropathy in diabetic patients and could help the physicians in controlling the occurrence of renal failure.Sixty Iraqi type 2 diabetes mellitus patients attending the National Diabetes Center for Treatment and Research at Al - Mustansiriyah University during the period October 2014 - June 2017 were recruited for this study. For the purpose of comparison, 20 control subjects matched for age, gender and ethnic background were also included. The patients and controls were characterized in family history of diabetes, diabetic nephropathy groups divide by used Albumin to creatinine ratio. The patients were also assessed for duration of disease, fasting serum glucose, and serum creatinine and blood urea.The mean urinary level of MCP - 1 (15.38±15.50 vs. 6.10±7.23pg/ml) and IL - 18 (35.90±16.67 vs. 23.55±12.67pg/ml) and osteopontin (337.15±257.06 vs. 174.11±183.65ng/ml) and nephrin (100.01±88.66 vs. 52.23±19.61ng/ml) were significantly higher in T2DM patients as compared to controls.The mean levels of urinary MCP - 1, uIL - 18 and osteopontin in macroalbuminurea group of patients were significantly higher than those in normoalbumine ( p < 0.008, p< 0.0001 and p< 0.03 respectively), and only of the Nephrin in the normoalbuminurea group of patients showed significant increased level as compared to the controls (52.23±19.61 vs.75.05±37.8 ng/ml) (p<0.022).The duration of disease showed an increase in mean of urinary level for all the markers MCP - 1, IL - 18, osteopontin and nephrin (17.01±18.09 vs. 19.76±21.30 pg/ml, 29.24±15.98 vs. 42.98±17.25pg/ml, 321.1±291.05 vs. 409.05±210.0ng/ml, 99.40±48.40 vs. 79.21±44.23 ng/ml) respectively, in late duration of disease as compared with early duration of disease except in Nephrin showed the early duration of disease higher than the late duration of disease (99.40±48.40 vs. 79.21±44.23), although the differences were not significant.The Receiver operating characteristic (ROC) curve analysis for all markers MCP - 1, IL - 18, Osteopontin and Nephrin levels (MCP - 1 = 0.72, IL - 18 = 0.71, Osteopontin =0.70 and Nephrin =0.72) for early diagnosis and detection of DN revealed that the cut - off value of uMCP - 1 was 6.23 pg/mg with 70% sensitivity and 75% specificity; whereas, the cut - off value of u IL - 18 pg/ml was 23.69 ng/mg with 80% sensitivity and 59% specificity and Nephrin was 49.5 ng/ml with 78% sensitivity and 55% specificity. uOsteopontin was 182 ng /ml with 68% sensitivity and 69% specificity.The linear correlation revealed a significant positive linear correlation between urinary MCP - 1, IL - 18, Nephrin and A : C ratio, also showed a significant negative linear correlation between urinary MCP - 1, IL - 18, osteopontin and GFR.In conclusion the Nephrin may be considered as potential diagnostic and prognostic biomarker a for the early detection and progression of diabetic nephropathy while the uMCP - 1, uIL - 18 and uOsteopontine may be considered as potential prognostic biomarkers for the diabetic nephropathy. The duration of disease also affect investigated biomarkers suggesting the long term effect of hyperglycemia

تقدير مستويات السايتوكينات (الحركيات الخلوية) المولدة للالتهاب والمضادة للالتهاب لدى مرضى فصال العظام في الركبة قبل وبعد الحقن بالبلازما الغنية بالصفيحات الدموية == Estimation Of Pro - Inflammatory And Anti - Inflammatory Cytokines In Patients With Knee Osteoarthrosis Before And After Injection With Platelets - Rich Plasma (Prp)

اسم المؤلف: حسنين خضير عبد العباس
اسم المشرف: عبد العظيم ياسين عبود البراك | سامر محمد رضا عنون | زيد وجيه رؤوف الشهواني
الموضوع العام: الطب
السنة: 2016
الموضوع الدقيق: الاحياء المجهرية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: التهاب العظام والمفاصل Osteoarthrosis)) او فصال العظام او ما يعرف بالاسم الشائع السوفان هو مرض يحدث في غضروف المفصل الذي يعمل على عدم احتكاك عظام المفصل ,مما يؤدي الى تقليل هذه الحماية ضد الاحتكاك فتصبح حركة المفصل بها خشونة ومصحوبة بالالام عند استخدام ا | Osteoarthrosis (OA) are defined as a progressive architecture destruction of the joints compared to slow healing of these joints which leads to reduce protection against degeneration and the movement of the joint is associated with by the roughness and accompanied by pain when using the joint. Often this disease affect the knee joint, it may affect any other joint in the body, especially those that carry weights such as leg hinges the pelvis, elbow and spine. The aim of this study is to evaluate the efficacy of platelets - rich plasma injection in osteoarthritis knee and the estimation of the biological and immunological markers associated with the treatment. This study involved 50 patients suffering from inflammation of the knee joint under supervision of speiclist of orthopedic ,most of these patients attended Al - Shaheed Firooz hospital in wasit Governorate and specialty private clinics of orthopedic and Rheumatology in the district during the period from April 2015 until October 2015.The age of patients was about 35 - 65 years; 31 females and 19 males with 25 healthy matching group. All patients were injected into the knee joint by a specialist physician with two injections during two months with platelets - rich plasma (PRP)after its preparation from the same patient's blood in sterile conditions. This was done after the signing of the patient or one of his relatives on the written consent to conduct the injection process after explaining and clarifying the principle of injection and the purpose. The level of pain of patients group was measured by Visual Analogue Scale (VAS). The enzyme linked immunnosorbant assay ELISA method to determine the level of some of cytokines in serum of patients group (interleukin - 1beta, tumor necrosis factor - alpha,IL - 10,IL - 8 and Transforming growth factor - B1) in addition to measuring the concentration of C - Reactive protein (CRP).The rate of Erythrocyte Sedimentation Rate (ESR) was also estimated. All were done to all patients groups before and after injections with PRP in addition to healthy group. Statistical analysis showed no significant differences between males and females (54.5±1.2 males, 53.2±2.1 females). The study showed significant decrease in the mean of the Visual Analogue Scale (VAS) of patients before and after two months of injections with (PRP) 8.46 ± 0.104, 5.98 ± 0.129, , respectively, with highly significant differences (P=000.0) , also the study showed that there was no significant differences in VAS between age groups (30?s, 40?s, 50?s , 60?s) before and after injections with PRP (7.5,8.0 ,8.38 ,9.05), (5.0,5.55,5.69,6.7) respectively. The study also showed a difference in the mean for inflammatory marker C. Reactive protein concentration before and after injections with PRP 7.156± 0.328 µg/ml, 5.384± 0.196 respectively, in comparison with healthy group with highly significant differences (P=0.000).The study also showed a difference in the mean of ESR before and after injections with PRP (35.66± 0.879 mm/1hr, 23.7±0.856) respectively, with in comparison with healthy group highly significant differences (P=0.000).The mean of Interleukin 1 - Beta(IL - 1?) was decline after injections with PRP from 13.220±0.295, pg/ml to 9.622 ± 0.273 pg/ml in comparison with healthy group with highly significant differences (P=0.000). Also a decline in the mean of Tumor necrosis factor - alpha (TNF - ?) after injections with PRP from 62.384±0.927 pg/ml to 55.36 ± 1.121 pg/ml in comparison with healthy group with highly significant differences (P=0.000). The study also demonstrates a decrease in the mean of Interleukin - 8 (IL - 8) before and after injections with PRP (41.092±0.808 pg/ml, 35.93 ± 0.813pg/ml) respectively in comparison with healthy group with highly significant differences (P=0.000). An increase in the mean of Interleukin - 10(IL - 10) after injections with PRP from 5.108±0.291 pg/ml to 6.734±0.330pg/ml, in comparison with healthy group with highly significant differences (P=0.000). The final parameter in this study was demonstrated an increase in the mean of Transforming growth factor - ?1 (TGF - ?1) before and after injections with PRP (111.544±6.960, 149.212±7.540pg/ml) respectively in comparison with healthy group with highly significant differences (P=0.000). Association was obtained between VAS score and C. RP as well as ESR after treatment. PRP treatment also has an impact on increasing the level of anti - inflammatory IL - 10 and TGF - ?1 on one side and the decreasing level of pro - inflammatory IL - 1?, TNF - ?,IL - 8 (catabolic marker) on the other side these results suggest the inhibition of catabolic process demonstrated by reducing of VAS scores and the efficacy of effectiveness plasma rich platelets (PRP) treatment of osteoarthrosis.

دراسة التعبير المناعي النسيجي الكيميائي لبعض المعلمات المناعية في مختلف درجات سرطان البروستات == Study The Immunohistochemical Expression Of Some Immunological Markers In Different Grades Of Prostate Cancer

اسم المؤلف: حسن هادي زريج
اسم المشرف: زينب فاضل عاشور | وسن عبد الاله باقر
الموضوع العام: الطب
السنة: 2015
الموضوع الدقيق: الاحياء المجهرية
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Prostate cancer is the most common malignancy and the second leading cause of cancer related death among males worldwide. Prostate cancer developed in prostate , a gland that is located below the bladder and just in front of rectum.Inflammation is a fundamental physiological process that can arise in any tissue in response to traumatic, infectiousor autoimmune injury. Transforming growth factor beta one (TGF - ?I) is a potential regulator of prostate cancer cell growth that signals through a heteromeric complex composed of type I and type II receptors.TGF - ?R II is an important receptor , because TGF - ? bind to receptor II to initiate it's signaling, then receptor II recruits receptor I to initiate signal transduction. Interleukin - 17 (IL - 17) is a pro - inflammatory cytokine produced by T - helper 17 (Th17) cells contributes toboth the processes by playing a dual role in the antitumor immunity. On one hand, IL - 17 encourages an antitumor cytotoxic T cell response leading to tumor regression. On the other hand, by promoting angiogenesis and egress of tumor cells from the primary focus, so IL - 17 promotes tumor growth.This study was carried out to establish the correlation between expression of Transforming growth factor beta one(TGF - ?I), Transforming growth factor beta receptor one (TGF - ?RI) and Transforming growth factor beta receptor two (TGF - ?RII) and prostate cancer progression. Also to establish the role of IL - 17 in prostate cancer development.The study consisted of 16 patients with poorly differentiated malignancy (PDM) ,whose age ranged (48 - 89) years, with mean age of (71.2) years , and 25 patients with moderately differentiated malignancy(MDM) , whose age ranged (31 - 83) years , with mean age of (66.6) years , and 46 patients with benign prostatic hyperplasia (BPH) , whose age ranged (27 - 85) years , with mean age of (64.3) years. Allpatients were diagnosed surgically by consultant physicians in Baghdad hospital for specialist surgeries , Al - Yarmook teaching hospital ,as well as AL - Hilla teaching hospital , and 20 normal tissue sample taken from cadaver, whose age ranged (17 - 28) years , with mean age of (21.8) years , where chosen as a control group. The work was conducted in Iraqi center for cancer and medical genetic researches. The study were performed during the period from March 2014 to December 2014).Immunohistochemistry (IHC) technique was used to detect the level of expression of TGF - ?I , TGF - ?RI , TGF - ?RII and IL - 17 protein in tissues of patients and healthy control groups.The current study revealed that there was significant difference in mean levels of TGF - ?I protein expression between each of poorly and moderately differentiated malignancy compared with healthy control subjects with P - value of 0.001 , but there was no significant difference in mean level of TGF - ?Iprotein expression between benign prostatic hyperplasia and healthy control subjects with P - value of 0.398. Also there was no significant difference between poorly and moderately differentiated malignancy in mean level of TGF - ?I protein expression.TGF - ?R1 protein was expressed in 3 (18.7%) and 14 (56%) of poorly and moderately differentiated malignancy respectively , with weak immunostaining reaction was the most frequent score. There was significant difference in mean level of TGF - ?RI protein expression among all studied groups. TGF - ?RII protein was expressed in 6 (37.5%) and 22 (88%) of poorly and moderately differentiated malignancy respectively ,with weak immunostaining reaction was the most frequent score. There was significant difference in mean level of TGF - ?RII protein expression among all studied groups.IL - 17 immunohistochemical expression was detected in tissues of all studied groups , the results showed that moderate immunostaining reaction was the most frequent score among them. There was significant difference in mean levels of IL - 17 protein expression among all studied groups.We concluded that there was statistically significant association between the loss ofexpression of TGF - ?1 signaling receptors, especially TGF - ?RI, andincreasing grades of malignancy in prostate cancer. These resultssuggest a potential mechanism for prostate cancer cells toescape the growth inhibitory effect of TGF - ? and thus, leadingto a more malignant phenotype.

دراسة التنميط الجيني لفيروس الSEN في متبرعي الدم الاصحاء ومرضى الثلاسيميا المصابين وغير المصابين بفيروس التهاب الكبد نمط ج واهميته السريرية == Genotypic Study Of SEN Virus In Healthy Blood Donors And Thalassemia Patients; With Or Without HCV Infection And Its Clinical Importance

اسم المؤلف: بشار منذر خزعل الزبيدي
اسم المشرف: اروى هادي الحمداني | اشنا جمال فائق
الموضوع العام: الطب
السنة: 2015
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Blood transfusion is one of the most common routes of viral hepatitis transmission among population. There are several diseases need continuous blood transfusions to manage the patient's condition; one of these diseases is ?thalassemia, so these patients are at increased risk of infection with blood transfusion transmitted agents. SEN - Virus is a DNA virus which is associated with acute post - transfusion hepatitis and the prevalence with the clinical importance and also the genetic characterization are still much unknown in Iraq; therefore, this study was designed to investigate the occurrence and the clinical importance of SEN - virus infection in healthy blood donors and thalassemia patients with or without HCV infection and then the study of the genome sequencing and the phylogenetic analysis of SEN - V clones. One hundred and fifty eight thalassemia patients (57.6% male, 42.4% female), with mean age of 16.8±8.5 year, and one hundred and fifty healthy blood donors with randomly selected persons (58.7%male, 41.3% female), with mean age of 16.7±8.6 year. All these samples involved in this study that were conducted in the period between January to June 2015. SEN - V had been identified by DNA extraction, DNA amplification by nested conventional PCR and then Agarose gel electrophoresis amplified DNA bands detection; while HCV was identified by RNA extraction, RNA reverse transcription into complementary DNA, DNA amplification by nested conventional PCR and then Agarose gel electrophoresis amplified DNA bands detection. Liver transaminases (Aspartate Transaminase and Alanine Transaminase) were determined, in addition of measure of serum ferritin levels by VIDAS. SEN - V was detected in 68 out of 158 (43%) thalassemia patients and 16 out of 150 (10.7%) blood donors. HCV prevalence was (11.4%) in thalassemia patients. There was significant increase observed in the occurrence of SEN - V or HCV infection with age but there was no significant difference observed in the occurrence of both with gender. The most important (hepatotropic) SEN - V genotypes were SEN - V - D and SEN - V - H and there were patients infected with D genotype or H genotype alone, while there were patients co - infected with D and H. According to HCV and SEN - V co - infection status, patients and controls subdivided into six subgroups : subgroup I was thalassemia HCV RNA + and SENV DNA +, subgroup II was thalassemia HCV RNA + and SEN - V - , subgroup III was thalassemia HCV RNA - and SEN - V DNA +, subgroup IV was thalassemia HCV RNA - and SEN - V - , subgroup V was control SEN - V + and finally subgroup VI was control SEN - V - . Statistical analysis revealed that there was significant increase in AST and ALT levels in subgroup I when compared with the other subgroups - that showed the increasing relationship in the case of infection with both viruses - and there were no any significant differences in ferritin levels among these subgroups. Moreover, there were no significant differences between SEN - V - D, SEN - V - H and SEN - V - D and H co - infected samples in AST, ALT and ferritin among thalassemia patients and controls. The results from the study of gene sequencing and phylogenetic analysis of samples of amplified SEN - V - D and samples of amplified SEN - V - H DNA which were selected randomly from blood donors and thalassemia patients infected with D or H genotypes alone or together (co - infection), revealed that the most transmission route of SEN - V D and H was blood transfusion that is because there was (99%) gene similarity between blood donors and thalassemia patients, furthermore SEN - V - D or SEN - V - H sequences of the co - infected persons were the same sequences of D or H genotypes alone and with the observations of similarity with neighboring countries.

Immunological Status Of Seminal Plasma For Bodybuilders On Androgenic Anabolic Steroid Hormones == Immunological Status Of Seminal Plasma For Bodybuilders On Androgenic Anabolic Steroid Hormones

اسم المؤلف: Anwar M. Rasheed Abdulhussein
اسم المشرف: Dr.Abduladheem Y. Abbood AL.Barra
الموضوع العام: الطب
السنة: 2016
الموضوع الدقيق: الطب
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: Exercises done by bodybuilder have great benefit for the general health and muscle size and performance. Anabolic androgenic steroid hormones are commonly used by bodybuilders to increase muscle mass and strength depending on its mode of action to increase the level of nitrogen retention in muscle, insulin like growth factor IGF - 1 increase in muscle tissue and seminal fluid. IGF - 1 responsible for Cell proliferation, growth and inhibiting apoptosis activity. Also AAS generally has an immunmodulatory impact on cytokines interactions as well as infertility. This study was designed to estimate the changes in cytokines in seminal plasma, sperm count in the seminal fluid and estimation of testosterone concentration in serum due to the impact of androgenic anabolic steroids hormones in bodybuildrs. Eighty male volunteers their age groups are ranging from 21 - 35 years. They were divided into three groups; the first group 27 age matched volunteers apparently healthy (healthy control group) , Second group 27 bodybuilders players attending the sport club with androgen anabolic steroid hormone abuse (AAS) (steroid group), and the third group 26 bodybuilder players attending this sport club in Baghdad without AAS uptake (fitness group ). A blood sample and seminal fluid were obtained from each individual involved in this study. Blood, serum and seminal plasma were prepared from these samples were obtained and applied for estimation of testosterone level by using enzyme immuno - florescent technology. Anti - sperm Ab test by heamo - aglutenation method was used to exclude the positive cases from this study.Heparinized blood was used for estimation of neutrophil phagocytic activity Sperm count was done for each seminal fluid sample, cytokines were estimated by sandwich ELISA method, in seminal plasma, these cytokines are IL - 6, IL - 10,IL17a,TNF - ? and INF - ?. The bodybuilders with AAS uptake showed a significant reduction in sperm count (P=0.00), fitness group sperm count showed slight nonsignificant decrease compared to healthy control group (P=0.7). Serum testosterone level in the AAS uptake group showed a significant decline compared with fitness and healthy control groups (P= 0.00). Exercise alone increases the level of IL - 6 (P=0.00), while exercise with AAS uptake decreases the level of IL - 6 (P=0.06). The fitness group showed highly significant increases in TNF alpha (P =0. 00). IL - 10 as an anti - inflammatory cytokine shows a high level in the AAS uptake group compared to the healthy group (0.04). IL - 17 as an inflammatory cytokine showed high significant increase in steroid group and fitness group (P=0.00), which indicate that both exercises with and without AAS uptake increases the level of IL - 17 secretion(P= 0.02) separately or in combination. Phagocytosis of AAS uptake group showed a highly significant decline (P= 0.00).The correlation results showed that there is a complex network interactions between the studied cytokines. The Phagocytic activity of the AAS uptake group showed a strong correlation with both IL - 6 and IL - 10 levels. IL - 10 as a suppresser cytokine has a significant correlation with TNF - alpha, INF - gamma and IL - 17A while, IL - 10 showed a negative correlation with IL - 6. IL - 17 which act as an inflammatory cytokine has a significant correlation with all cytokines except IL6 and phagocytic activity. Generally seminal plasma cytokine network may be under the effect of immune regulation mechanism and cytokine inactions as well as, the impact of steroids uptakes. In general the final impact of AAS uptake on bodybuilders immunity are declining in phagocytosis and an increase in IL - 10 which act as suppressor to the Th1 immune response and increase of IL - 17 which has a role in increasing the inflammatory response so, these results suggest that AAS abuse players may be more liable for infection and decrease in sperm count which may cause temporary or permanent infertility.

دراسة المقاومة المتعددة للمضادات الحيوية لعصيات التدرن لدى مرضى التدرن الرئوي == A Study On Drug Resistance Of Mycobacterium Tuberculosis Isolated From Pulmonary Tuberculosis Patients

اسم المؤلف: انمار ليث طالب الحسني
اسم المشرف: عامر رشيد النجار | احمد اسمر منخي
الموضوع العام: الطب
السنة: 2016
الموضوع الدقيق: الاحياء المجهرية
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: تعتبر عزلات جراثيم التدرن المقاومه للادوية من المشاكل الرئيسية في معالجة مرضى التدرن حول العالم. , ولاهميته اجريت هذه الدراسة لتسليط الضوء اكثر حول الحساسيه الدوائية بواسطة الطرق المختبرية التقليدية وعلى الوسط الصلب ومقارنته مع الطرق التشخيصية المختبرية ا | Drug resistant tuberculosis remained as major problems in the treatment of tuberculosis patients in the world. A prospective study was conducted to evaluate drug susceptibility testing (DST) by classical methods on solid media as compared with advance and molecular Laboratory diagnostic methods (Bactec MGIT 960 and GeneXpert MTB - RIF ). The study included the estimation of the first line anti - TB drugs, including (Rifampicin,Isonizid,Streptomycin and Etambutol) by solid media (Lowenstein - Jensen medium) and Bactec MGIT 960 system. In addition, the use of rapid molecular diagnostic method by GeneXpert MTB/RIF assay. Seventy five TB patients attending the National Reference Laboratory of Tuberculosis /medical city - Baghdad from December 2015 to June 2016 were included in this study. Patients were classified into two main groups : selected MDR patients, which were referred from different hospitals and health respiratory center in Iraq, represented 46 in order to compare different laboratory methods to detect of DST isolates, while 29 were randomly isolated and identified , the study matched by age and gender were also included. This study revealed that the drug resistance tuberculosis to Rifampicin was 47 (62.7%), Isonizid 41 (54.7%), Streptomycin 42 (56.0%) and Ethambutol 38 (50.7%). Respectively , on the golden stander in which solid media were used.The molecular and advance technique (GeneXpert and Bactec MGIT 960) as applied to estimation of drug resistance tuberculosis, the results of drug susceptibility testing (DST), as showed highly sensitivity and Accuracy, when compared with golden stander( LJ media) especially in detected of primary drugs (Rifampicin and Isoniazid) and showed lower sensitivity and accuracy to detected of the secondary drugs (Streptomycin and Ethambutol). The Multiple drug resistance (MDR - TB) case from selective samples was found to be almost similar to that found in other countries of the middle east and other regions in the world. While in the randomly identified samples, the rate of MDR - TB was lower than the referred (previously treated) cases.The GeneXpert MTB - RIF system is rapid molecular methods that used in many countries to identify of MTB and Rifampicin detected during 2 hours only, that used in this study. The high Rifampicin resistance and other drugs of local isolates could be due to abuse of the drug,defaulter and relapse of retreating cases (previously treated).

دراسة التنميط الجيني لفيروس تي تي في مرضى الثلاسيميا المصابين وغير المصابين بفيروس التهاب الكبد نمط ج

اسم المؤلف: ابتسام نايف عودة الجبالي
اسم المشرف: اروى هادي الحمداني
الموضوع العام: الطب
السنة: 2014
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
المستخلص: ما زال الكثيرون لا يعرفون الاهمية السريرية لفيروس تي تي الذى رشح كاحد فايروسات التهاب الكبد انماط A - G)).ان فيروس تي تي يصيب المرضى المعرضين لخطر الحقن ونقل الدم المتكرر، كما في المرضى المصابين بفقر دم البحر الابيض المتوسط(? - Thalassemia major). تمت هذة | Much is still unknown about the clinical significance of TT virus (TTV) that has been reported as a candidate for non A - G hepatitis virus. TTV infects patients at risk for parenteral exposure and chronic blood transfusion, such as those with ? - thalassemia major. This study was designed to investigate the prevalence and clinical importance of TTV infection in thalassemia patients with or without hepatitis C virus (HCV) co - infection, furthermore to sequence and analyse phylogentic of TTV clones.One hundred fifty four thalassemia patients (64.3% male, 35.7% female) with a mean age of 23.8±6.8 years were involved in this study that was conducted in the period between Feb. to Dec. 2013. TTV DNA was detected using Real time PCR. Furthermore, conventional PCR was done for sequencing and phylogenetic analysis using N22 region from open reading frame 1 (ORF1). Anti - HCV antibody was determined by Enzyme Linked Immunosorbent Assay (ELISA) and confirmed by western blot. Then, HCV core antigen was detected in those anti - HCV Abs seropositive samples. Liver transaminases (ALT, AST) were determined, in addition to measure serum ferritin levels by VIDAS ferritin. TTV was detected in 45 of 154 (29.2%) of thalassemia patients with predominance of males than females (64.4% vs. 35.6%). The prevalence rate of anti - HCV Abs were 54.5% with significant increase in females than males (p<0.05).Out of these 84 samples, 59 (70.2%) were positive by HCV core Ag assay and related significantly to frequency of blood transfusion. According to HCV and TTV infection status, patients were categorized into six groups : Anti - HCVAb+ HCV core Ag + TTV+, Anti - HCVAb+ HCV core Ag + TTV - , Anti - HCVAb+ HCV core Ag - TTV+, Anti - HCVAb+ HCV core - TTV - , Anti - HCVAb - TTV+, Anti - HCVAb - TTV - . The increased levels of ALT, AST and ferritin in the HCV and TTV infected group were not significantly different from those in the TTV and HCV negative groups. Co - infection of TTV and HCV were significantly increase ALT levels compared to infection with HCV alone. No association of TTV infection was found with gender, age and frequency of blood transfusion.The results of genotyping in 12 randomly selected patients showed the presence of equal percentage of genotype 1 (G1) and genotype 2 (G2) 50% for each one, with homology between them 79.0%. Other TTV genotypes were not identified in the present study suggesting that G1and G2 are predominant in this area. Mixed infection of the same patient with multiple TTV genotypes was observed. The results concluded that TTV is moderately present in Iraqi thalassemia patients, with G1 and G2 were predominant. Patients co - infected with HCV and TTV had a significantly higher serum ALT level than those without TTV infection, so TTV infection is suggested to have a role in increasing the severity of liver diseases in the thalassemia patients when co - infected with HCV.

محاكاة كومبيوترية لتقليل الجرعة الاشعاعية مع الابقاء على نفس مستوى صورة المفراس لمرضى ذوي احجام متنوعة == Computer Simulated Dose Reduction With The Same Quality Of CT Images For Patients Of Various Sizes

اسم المؤلف: فراس محمد عبد القادر
اسم المشرف: عبد الرضا صاحب يونس الساعدي | شذى عبد الصاحب علش
الموضوع العام: الطب
السنة: 2007
الموضوع الدقيق: الفيزياء الطبية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

رؤى فايروسية ومناعية في البيئة المجهرية لانسجة المشيمة للمجهضات المصابات بفايروسات الحلا == Virological And Immunological Insights Into Placental Tissue Microenvironment Of Aborted Patients Infected With Human Herpes Viruses

اسم المؤلف: زينب عبد الحسين حامد
اسم المشرف: سعد حسن محمد علي | باسم شهاب احمد
الموضوع العام: الطب
السنة: 2014
الموضوع الدقيق: الاحياء المجهرية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

دراسة دور العقدية الرئوية والرشاشية الدخناء في مرضى الربو : دراسة مصلية جزيئية == Study On The Role Of Streptococcus Pneumoniae And Aspergillus Fumigatus In Asthma : Serological And Molecular Diagnosis

اسم المؤلف: اياد صالح مهدي
اسم المشرف: عامر رشيد النجار | امنة نعمة الثويني
الموضوع العام: الطب
السنة: 2016
الموضوع الدقيق: الاحياء المجهرية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

المكورات العنقودية الذهبية المقاومة للمثسيلين بين العاملين في المستشفى والمجتمع وتميز وجود جين Luks_Lukf == Methicillin - Resistant Staphylococcus Aureus (MRSA) Among The Hospital Staff And Community With Focus On The Presence Of luks - lukf PVL Gene

اسم المؤلف: الاء علي جواد
اسم المشرف: عروبة خالد عباس | سراب خاشع الراوي
الموضوع العام: الطب
السنة: 2016
الموضوع الدقيق: الاحياء المجهرية
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

استخدام الذكاء الاصطناعي في تميز اصوات القلب لامراض الصمامات القلبية == Artificial Intelligence In Recognition Of Heart Sound In Valvular Heart Diseases

اسم المؤلف: نهاد عبد الامير صالح المعموري
اسم المشرف: Riad A. Al | Ramadhni | Abdul | Redha S. Al | Saidy
الموضوع العام: الطب
السنة: 2005
الموضوع الدقيق: الفيزياء الطبية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تقييم بعض جوانب تغيرات الدم في الاشهر الثلاثه الاخيره من الحمل == Study Of Some Hematological Parameters In The Third Trimester Of Pregnancy

اسم المؤلف: عمر صالح وتوت
اسم المشرف: سعد شوقي منصور
الموضوع العام: الطب
السنة: 2004
الموضوع الدقيق: الامراض - الدم
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تاثيرات الادوية المضادة للاكسدة ( فيتامين C وفيتامين E والاسبرين ) في حالات مرض الاوعية المحيطية == Effects Of Antioxidants (Vitamin C, Vitamin E And Aspirin) On Peripheral Vascular Disease

اسم المؤلف: سعد بداي نشتر
اسم المشرف: سليم محيي حسن | غالب عبد زيد الشريفي
الموضوع العام: الطب
السنة: 2004
الموضوع الدقيق: الادوية والسموم
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

دراسة وبائية للتدرن المعند في العراق == Epidemiological Study Of Multi - Durg Resistant Tuberculosos In Iraq

اسم المؤلف: هناء بهجت احمد التميمي
اسم المشرف: محمد جواد كاظم
الموضوع العام: الطب
السنة: 2008
الموضوع الدقيق: طب المجتمع
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

دور الاقران في نشر الثقافة الصحية بين طلاب المدارس الثانوية في الحلة == Peer Health Education Role Among Al - Hilla Secondary School Students

اسم المؤلف: ماهر جواد كاظم
اسم المشرف: وليد عارف العاني
الموضوع العام: الطب
السنة: 2012
الموضوع الدقيق: طب المجتمع
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

العنـف ضـد الاطفال عينة من بغـداد == Violence Against Children : A Sample From Baghdad

اسم المؤلف: لباب عدنان جابر
اسم المشرف: رياض خضير لفتة
الموضوع العام: الطب
السنة: 2007
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

التحري عن التهاب الكبد الوبائي (النوع البائي والنوع السيني) لدى عينه من النساء الحوامل في مدينة الفلوجه == Screening For Hepatitis B And Hepatitis C Viral Infection Among A Sample Of Pregnant Women In Fallujah City

اسم المؤلف: كفاح عبد اللطيف محسن
اسم المشرف: نجلاء فوزي الجسار
الموضوع العام: الطب
السنة: 2011
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

انتشار اضداد فيروس انتفاخ الخلية نوع IgG لمرضى داء السكري في بغداد == Epidemiological Study Of Cytomegalovirus IgG Antibodies Among Diabetic Patients In Baghdad

اسم المؤلف: فراس يونس محسن
اسم المشرف: جمال رشيد الراوي | عباس مهدي رحمة
الموضوع العام: الطب
السنة: 2008
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

نمط حياة البدناء == Lifestyle Of The Obese

اسم المؤلف: علي حسن حياوي
اسم المشرف: رياض خضير لفتة
الموضوع العام: الطب
السنة: 2003
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

المشاكل الطبية والاجتماعية لدى العوائل التي تراسها امراة == Medical And Social Problems Among Women - Headed Families In Baghdad

اسم المؤلف: علي حسن حياوي
اسم المشرف: رياض خضير لفتة | جمال محمود الخضيري
الموضوع العام: الطب
السنة: 2011
الموضوع الدقيق: طب المجتمع
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

التاخر في تشخيص وعلاج مرض التدرن الرئوي في محافظة الانبار == The Delay In Diagnosis And Treatment Of Pulmonary Tuberculosis In Al - Anbar Province

اسم المؤلف: عبد الحكيم خلف لطيف الجميلي
الموضوع العام: الطب
السنة: 2004
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

معدل وانواع سرطانات الجلد في سبع مراكز رئيسية في بغداد == Rates And Types Of Skin Cancers In Seven Main Centers In Baghdad

اسم المؤلف: عباس فضال حمادي
اسم المشرف: محمد جواد كاظم | جمال رشيد الراوي
الموضوع العام: الطب
السنة: 2012
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

استخدام خدمات الرعاية لما بعد الولادة في عينة من النساء في بغداد \ الكرخ == Utilization Of Postnatal Care Services In A Sample Of Women In Baghdad/ Al - Karkh

اسم المؤلف: شيماء رفعت نافع
اسم المشرف: نجلاء فوزي جميل
الموضوع العام: الطب
السنة: 2013
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

ادراك النساء عن مرض هشاشة العظام وعوامل الخطورة ذات العلاقة في بعض مناطق بغداد == Awareness Of Women About Osteoporosis And Its Related Risk Factors In Certain Areas In Baghdad

اسم المؤلف: زينب نبيه اسماعيل
اسم المشرف: لمياء ضياء الدين بهاء الدين
الموضوع العام: الطب
السنة: 2013
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

مدى انتشار التهاب الجلد التاتبي عند الاطفال في المدارس الابتدائية - محافظة بغداد / الكرخ == Prevalence Of Atopic Dermatitis Among Primary School Children In Baghdad - Alkarkh District

اسم المؤلف: رائدة خضير جاسم
اسم المشرف: جمال رشيد الراوي
الموضوع العام: الطب
السنة: 2004
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تحري فايروس اللمفومة وابيضاض الدم نوع 1 و2 لدى المرضى العراقيين المصابين باللمفومة وابيضاض الدم == Screening For HTLV 1 & 2 Among Iraqi Patients With Lymphoma And Leukemia

اسم المؤلف: ايمن محمود عبد اللطيف
اسم المشرف: جمال رشيد الراوي | غالب عبد الشريفي
الموضوع العام: الطب
السنة: 2009
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

الاسباب العشرة الاولى للوفيات بين الاشخاص العسكريين == The Ten Leading Causes Of Death Among Military Personnel In Baghdad For The Years (1999 - 2001)

اسم المؤلف: ايمان غالب محمد
اسم المشرف: محمد جواد كاظم
الموضوع العام: الطب
السنة: 2002
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

دراسة وبائية لحالات المعتمدين على الكحول الراقدين في مستشفى ابن الرشد لعام 2004 - 2006 == Epidmiological Study Of Alcoholic Patients Admitted To Ibin Rushed Hospital During (2004 - 2006)

اسم المؤلف: الاء سليم توفيق
اسم المشرف: مازن غازي جاسم الربيعي
الموضوع العام: الطب
السنة: 2008
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

Prevalence Of Asymptomatic Urinary Tract Infection Through A Sample Of Primary School Children In Hilla Province

اسم المؤلف: اسراء عمران كاظم حلف السعدي
الموضوع العام: الطب
السنة: 2002
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تقييم بعض جوا نب خدمات الصحة المدرسية لطلبة الصف الاول الابتدائي في بغداد - ناحية الكرخ == Evaluation Of Some Aspects Of School Health Services For First Class Primary School Pupils In Baghdad - Kharkh District

اسم المؤلف: احمد خلف صوفي الدليمي
اسم المشرف: نجاة محمد فخري البياتي
الموضوع العام: الطب
السنة: 2004
الموضوع الدقيق: طب المجتمع
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

فهرس حجم البروتينات الدهنية واطئة الكثافة والجهد التاكسدي عند معالجة المرضى المصابين بالمراحل المتاخرة من عجز الكلية == LDL Particles Size Index And Oxidative Stress In Treated Patients With End Stage Renal Disease

اسم المؤلف: هند محسن الجنابي
اسم المشرف: ثابت نعمان وحيد العزاوي | غسان عبد الامير الشماع
الموضوع العام: الطب
السنة: 2004
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تاثير اختلالات الغدة الدرقية على مستويات عامل النمو شبيه الانسولين 1(IGF - 1) وهرمون النمو(GH) في مصل الدم == Effects Of Thyroid Disorders On Serum Insulin - Like Growth Factor (IGF - 1) And Growth Hormone (GH) Levels

اسم المؤلف: هدى جابر وحيد
اسم المشرف: مثنى عبد الغني عبد الكريم | عباس مهدي الموسوي
الموضوع العام: الطب
السنة: 2009
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

مدى انتشار الامراض الذهنية عند اليافعين في المدارس الثانوية في محافظة الديوانية2011 == Prevalence Of Mental Disorders Among Adolescents Of Secondary Schools In Diwaniya Governorate

اسم المؤلف: هادي جبر سهيل
اسم المشرف: مازن غازي جاسم الربيعي | علي عبيد جعاز
الموضوع العام: الطب
السنة: 2011
الموضوع الدقيق: طب المجتمع
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

تقييم وضعية بعض المعادن عند مرضى اختلالات الغدة الدرقية == Evaluation Of Some Minerals Status In Patients With Thyroid Disorders

اسم المؤلف: محمد عبد الجليل زيارة الكعبي
اسم المشرف: عدنان فاضل النجار
الموضوع العام: الطب
السنة: 2008
الموضوع الدقيق: الكيمياء الحياتية الطبية
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

دراسة كيمياحياتيه لـ CA 125 , HCG ودلائل كيمياحياتيه اخرى في انواع مختلفة من سرطان المبيض == Biochemical Studies Of CA125, HCG And Other Biochemical Parameters In Patients With Different Types Of Ovarian Cancer

اسم المؤلف: محمد داود عبد الحسين
اسم المشرف: ناصر محمد فهد الربيعي | رياض محمد صالح
الموضوع العام: الطب
السنة: 2004
الموضوع الدقيق: الكيمياء الحياتية الطبية
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

اللبتين وبعض الفحوصات الكيمياء حياتية عند مرضى تضخم الغدة الدرقية == Leptin And Some Biochemical Parameters In Goitrous Patients

اسم المؤلف: فريال هاشم رضا
اسم المشرف: نهلة مجيد الصقال | عبد الكريم يحيى السامرائي
الموضوع العام: الطب
السنة: 2008
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:

دراسة التغيرات الحيوية لمتعاطي علاج املودبين بيزيليت او تلميزارتان لمعالجة ارتفاع ضغط الدم == Biochemical Changes In Patients Receiving Either Amlodipine Besylate Or Telmisartan For The Treatment Of Hypertension

اسم المؤلف: عهود خليل ابراهيم
اسم المشرف: مثنى عبد الغني عبد الكريم | فاضل محسن عبد
الموضوع العام: الطب
السنة: 2005
الدرجة: دكتوراه
اللغة: الانكليزية
مكان الجامعة: بغداد
الصفحات الاولى:
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