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تقدير البروتينات الدهنية والاجهاد التاكسدي في مصل المصابين بمرض حب الشباب == Evaluation of Serum Lipid Profile and Malondialdehyde in Patients with Acne

اسم المؤلف: رنا عبد العالي الرفيعي
الموضوع العام: علوم الكيمياء
السنة: 2008
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: النجف
الصفحات الاولى:
المستخلص: The present study was conducted to verify the relevance of lipids and lipoproteins levels and their byproduct of oxidation, malondialdehyde (MDA) in acne patients. The design of the project included one hundred acne patients (47% males and 53% females)and 40 apparently healthy individuals (control group). Total serum cholesterol (TC), high density lipoprotein cholesterol (HDL - C), triglycerides (TG), low density lipoprotein (LDL - C), very low density lipoprotein (VLDL - C) and MDA levels were measured in acne patients and the control group.The results indicated significant (P≤0.05) elevations for TC, TG, LDL - C, VLDL - C and MDA levels in acne patients with respect to those of the control group. Sex differences were obtained as rises forTC, LDL - C and MDA (P≤0.05) in males when compared with thoseof the females. The linear regression analysis exhibited significantpositive correlation for TC (r = 0.68, P≤0.05) and LDL - C (r = 0.48, P≤0.05) with ages of the control group but not in the acne patients.Smoker acne patients demonstrated significant elevations for TC, TG, VLDL - C, LDL - C and MDA (P≤0.05) in comparison with those of the control group, while nonsmokers acne patients showed significant elevations for TC and LDL - C (P≤0.05) during a comparable evaluation. Married acne patients indicated significant increases for TC, TG, VLDL - C, LDL - C and MDA (P≤0.05) when compared with those of the control group, while non married acne patients illustrated significant elevations for TG, VLDL - C, LDL - C and MDA (P≤0.05). The influence of treatment was studied, the data stated significant elevation for TG and LDL (P≤0.05), in treated acne patients when compared with those of the control group, while untreated acne patients showed significant increases for TC, TG, VLDL - C, LDL - C and MDA (P≤0.05) in comparison with those of the control group.These results suggested that oxidative stress is involved in the pathogenesis of acne. We believed that this study is the first to deal with changes of serum lipid profile and oxidative stress in acne patients.

دراسة الاطياف الاهتزازية والفعالية البايولوجية لبعض القلويدات == A study of the vibrational spectra and the biological activity of some alkaloids

اسم المؤلف: ايمان عبد الوهاب عبد الله الكويتي
اسم المشرف: عبد الرزاق عبد الجليل العيسى | حسين عبد الكاظم عبد الحسين
الموضوع العام: علوم الكيمياء
السنة: 2008
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: النجف
الصفحات الاولى:
المستخلص: The present study was conducted to extracts several alkaloids and their potency on the contraction of smooth’s Rat intestine .to achieve these aims : (Okra, Potato, Cilca ,Pomegranate, Sweet melon, Water melon, Eggplant , pumpkin , Quince , Oaks, Apple, Broad been ,Cauliflower ,Cinnamon ,spinach) were subjected to extraction by petroleum ether and ethanol.HPLC and Mayer’s test revealed significant amounts of pelletierin from punica granatum,lupanine from spinacia oleracea,sinaxalen from brassica oleracea,jasmonoyl tyrosine alkaloid from vica faba ,solanidine from solanum tuberosum and solanine from solanum melongena,in the enrolled plants.The amounts of these alkaloids were (0.22,0.015,0.043,0.036,0.041,0.031) mg/g Respectively .The interaction of alkaloids (0.1) g/L and the contraction of smooth muscle in rat was examined by IR spectroscopy. with the data exhibited stretching band of (C - N) bond in the rang of (1215 - 1020),as described in the literatures .The wave number of the stretching bands of (C - N)in alkaloids were found to be inversely proportional with the molecular weight of alkaloids .Alkaloids were found to elicit Rat intestinal strain according to the order Pelletierine>Lupanine>Sinaxalen>Jasmonoyltyrosine> Solanidine>Solanine.These results suggest the involvement of (C - N) bonds in alkaloids during the induction of smooth muscle contraction.

دراسة طيفية لامتزاز صبغتي الايوسين والزرقاء الفعالة على سطوح مخلفات الخشب == Spectrophotometeric study for Adsorption of Eosin and Reactive Blue on Sawdust wood Surfaces

اسم المؤلف: مرتضى عبد علي فرحان الجبوري
اسم المشرف: موسى عمران كاظم
الموضوع العام: علوم الكيمياء
السنة: 2008
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: النجف
الصفحات الاولى:

امتزاز بعض الادوية على سطح طين الكاؤولين العراقي الابيض == Adsorption of some drugs on the surface of white Iraqi kaolin clay

اسم المؤلف: جلال اسماعيل ابراهيم الكناني
اسم المشرف: سعد عزيز حسن حسوة
الموضوع العام: علوم الكيمياء
السنة: 2008
الموضوع الدقيق: الكيمياء الفيزيائية
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: النجف
الصفحات الاولى:

تقييم صورة الدهون المصلية والاجهاد التاكسدي لدى المتعاطيات حبوب منع الحمل == Evaluation Of Serum Lipid Profile & Oxidative Stress In Oral Contraceptive Users

اسم المؤلف: سيناء كاظم علي الحسيني
اسم المشرف: ماجد كاظم حسين
الموضوع العام: علوم الكيمياء
السنة: 2008
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: النجف
الصفحات الاولى:

تحضير بعض مركبات ازو - قواعد شف الجديدة، ودراسة فاعليتها الحيوية == Preparation and Characterization of Some New Azo - Schiff Bases and studying of its Biological Activity

اسم المؤلف: رجاء عبد الامير غافل
اسم المشرف: حسن ثامر غانم
الموضوع العام: علوم الكيمياء
السنة: 2008
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: النجف
الصفحات الاولى:

تقدير الكادميوم (II) والزئبق (II) طيفيا باستعمال الكاشف الجديد مشتق الازو بريميدين == Determination of Cadmium (II) and Mercury (II) Spectrophotometrically By using New Reagent Azo Primidine Derivative

اسم المؤلف: شيماء حمزة ديلي البديري
اسم المشرف: حسين جاسم محمد
الموضوع العام: علوم الكيمياء
السنة: 2008
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: النجف
الصفحات الاولى:

الاجهاد التاكسدي وفرط الدهون في داء السكري == Oxidative Stress And Hyperlipidemia In Diabetes Mellitus

اسم المؤلف: محمد عباس خليبص الناشي
اسم المشرف: ماجد كاظم حسين
الموضوع العام: علوم الكيمياء
السنة: 2008
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: النجف
الصفحات الاولى:
المستخلص: The present study aims at investigating the relationship b etween oxidative stress and hyperlipideamia in diabetes mellitus. For this purpose,(120) diabetes patients were chosen (48 type1 patients and 72 type2 patients). This sample of (120) patients was compared with a group of (50) healthy subjects. The malondialdehyde (MDA) (one of the markers of oxidative stress), serum total cholesterol(S.TC),triglycerides (S.TG) high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol(LDL) and very low density lipoprotein triglycerides (VLDL) were all measured via the enzymatic methods. Results indicated a significant increase(p<0.05) in the levels of (MDA),(S.TC),(S.TG),(HDL),(LDL) and (VLDL) in diabetes patients of both types, as compared with healthy subjects. The same fact holds when comparing the two types of patients. A significant increase (p<0.05) was also observed in the levels of (MDA),(S.TC),(S.TG),(HDL),(LDL) and (VLDL) in male and female diabetes patients of type1 as compared with healthy subjects. As for type2 patients the increase in the same values was(p<0.01) as compared with healthy subjects. The comparison of male and female patients showed a significant increase(p<0.05) in the levels of (S.TC),and (VLDL) only in type1. It was also found that age is an influential factor in the criteria of serum lipids and (MDA) levels in patients of both types, except in case of(S.TG)and(VLDL) in type2 patients where age proved irrelevant. Moreover, results indicated that (BMI) has an impact on (MDA),(S.TC),(S.TG),(LDL) and (VLDL) levels. The duration of the disease in patients of both types also produced a significant increase(p=0.05) in (MDA) levels and serum lipids criteria. The complications suffered by the patients because of diabetes also produced a significant increase (p<0.05 - p<0.005) in (MDA) levels and serum lipids criteria as compared with those free of such complications for both types. No significant correlation was found between MDA level and levels of serum lipids in all patients and in both types except(VLDL) in type2. All these results prove the correlative relationship between oxidative stress and serum lipids criteria in diabetes mellitus.