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دراسة الاطياف الاهتزازية والفعالية البايولوجية لبعض القلويدات == A study of the vibrational spectra and the biological activity of some alkaloids
اسم المؤلف:
ايمان عبد الوهاب عبد الله الكويتي
اسم المشرف:
عبد الرزاق عبد الجليل العيسى | حسين عبد الكاظم عبد الحسين
الموضوع العام:
علوم الكيمياء
السنة:
2008
الموضوع الدقيق:
الكيمياء
الدرجة:
ماجستير
الجامعة:
جامعة الكوفة - كلية التربية للبنات - قسم الكيمياء
اللغة:
الانكليزية
مكان الجامعة:
النجف
الصفحات الاولى:
📎 25T1561 - p.pdf
المستخلص:
The present study was conducted to extracts several alkaloids and their potency on the contraction of smooth’s Rat intestine .to achieve these aims : (Okra, Potato, Cilca ,Pomegranate, Sweet melon, Water melon, Eggplant , pumpkin , Quince , Oaks, Apple, Broad been ,Cauliflower ,Cinnamon ,spinach) were subjected to extraction by petroleum ether and ethanol.HPLC and Mayer’s test revealed significant amounts of pelletierin from punica granatum,lupanine from spinacia oleracea,sinaxalen from brassica oleracea,jasmonoyl tyrosine alkaloid from vica faba ,solanidine from solanum tuberosum and solanine from solanum melongena,in the enrolled plants.The amounts of these alkaloids were (0.22,0.015,0.043,0.036,0.041,0.031) mg/g Respectively .The interaction of alkaloids (0.1) g/L and the contraction of smooth muscle in rat was examined by IR spectroscopy. with the data exhibited stretching band of (C - N) bond in the rang of (1215 - 1020),as described in the literatures .The wave number of the stretching bands of (C - N)in alkaloids were found to be inversely proportional with the molecular weight of alkaloids .Alkaloids were found to elicit Rat intestinal strain according to the order Pelletierine>Lupanine>Sinaxalen>Jasmonoyltyrosine> Solanidine>Solanine.These results suggest the involvement of (C - N) bonds in alkaloids during the induction of smooth muscle contraction.
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