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تاثير المستخلص الكحولي الخام لاوراق الجت (Medicago sativa) على بعض المعايير الفسلجية والكيموحيوية في اناث الجرذان المستحثه بمادة الالوكسان == Effects of Crude Alcoholic Extract of Alfalfa (Medicago Sativa) Leaves On Some Physiological And Biochemical Parameters In Alloxan Induced Diabetic Female Rats

Author name: حوراء سليم محمد طه بشيبش

Supervisor name: عبد الزهرة كاظم محمد علي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

Abstract: اجريت هذه الدراسة في مختبر البحوث السريرية في كلية الصيدلة ومختبر فسلجة الحيوان في كلية العلوم / جامعة الكوفة للمدة من 15 / 9 /2011 الى 12 /3 /2012 للتقصي عن فعالية المستخلص الكحولي الخام لاوراق نبات الجت Medicago sativa L. في تخفيض مستوى سكر الدم وبعض ال | This study was conducted at the Clinical researches laboratory/ Pharmacy College and Animal physiology laboratory/ Sciences College / university of Kufa during the period from 15/ 9/ 2011 to 12 / 3/ 2012 to investigate the activity of the crud alcoholic extract of the alfalfa (Medicago sativa L). leaves in affecting the blood glucose level and some physiological and biochemical changes due to induced diabetes mellitus by alloxan (150) mg/kg in female albino rats (Ratus ratus), in comparison with the activity of the reference drugs Glibenclamide. This study was also used to know the effect of the extract in normal (healthy) female rats. In this study (54) female rats were utilized which were divided into (9) groups with 6 rats for each group. Diabetes mellitus was induced in (30) female rats, were distributed into 5 sub groups. One of them was considered as control group for the infected rats, and three groups of them were treated with different concentrations of the extract (250, 500 and 750)mg/kg while the fifth group was treated by the chemical drug Glibenclamide (0.6) mg/kg. The other 24 normal rats were also divided into 4 sub groups, one of them considered as control group. And the other three groups were treated with the extract concentrations (250, 500 and 750)mg/kg. The treating period with the plant extract and the drug continued for 30 day.Results of this study were as the following : ? A significant (P< 0.05) decrease was showen in total body weight, insulin hormone and HDL - c levels, total WBC and RBC count in addition to Hb concentration in infected group of diabetes mellitus in comparison with healthy control group.? A significant (P< 0.05) increase was clear in the levels of glucose, TC, TG, LDL - c, VLDL - c, urea, creatinine and ALT and AST enzymes in infected group in comparison with healthy control group.? The healthy rats that treated with the extract concentrations were showed a significant increase in their total body weight at the end period as compared with the first day of experiment, there was also a significant (P < 0.05) increase in body weights of the infected rats that were treated by the two concentrations (500, 750) mg/kg of extract as compared with infected control group.? The infected rats that treated by all three concentration of plant extract and the glibenclamid drug were exhibited a significant (P< 0.05) increase in insulin level as compared with infected control group.? on the other hand, it was also showen a significant (P< 0.05) decrease in glucose level of infected rats that have been treated by the three concentrations and the (0.6) mg/kg concentration of glibenclamid as compared with infected control group.? The levels of TC, TG, LDL - c, VLDL - c were significantly (P< 0.05) decreased, in contrast a significant increase was occurred in the level of HDL - c in infected rats when they treated by all the concentrations of plant extract as compared with infected control group.? The urea and creatinine levels showed a significant (P< 0.05) decrease when the infected rats were treated by the two concentrations (500, 750) mg/kg as compared with infected control group, while in the healthy rats, the urea level showed a significant (P< 0.05) decrease as compared with healthy control group.? A significant (P < 0.05) decrease was occurred in ALT enzyme level when the infected rats were treated by all extract concentrations and the chemical drug. But AST enzyme level was significantly (P < 0.05) decrease when the infected rats were only treated with the two concentrations (500, 750) mg/kg of plant extract in addition to glibenclamid as compared with healthy control group.? The two concentrations (500, 750) mg/kg of plant extract and the concentration (0.6) mg/kg of the glibenclamid drug caused a significant (P< 0.05) increase in total RBC count, and the hemoglobin concentration, while only the larger dose of plant extract caused a significant (P < 0.05) increase in total WBC count in infected rats as as compared with infected control group.In conclusion, the results of this study indicate that the two concentrations (500, 750) mg/kg of alfalfa leaves extract gave a good results, even better than the reference drug, glibenclamid for treating diabetes mellitus, in addition to ameliorate the metabolic disorders that accompany it.

عوامل الخطورة لطفرات الجينين CBS وMTHFR لقبل الارتعاج لدى النساء الحوامل في النجف == Risk Factors of CBS And MTHFR Gene Mutation For Preeclampsia In Pregnant Women In Al - Najaf

Author name: زهراء سامي رزاق النجار

Supervisor name: ظافرة جعفر عبد علي الفتلاوي | ماجد كاظم حسين

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - Faculty Of Education - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

Abstract: تعد الاصابة بقبل الارتعاجPre - eclampsia من الاعتلالات الخطيرة التي قد تظهر في الثلث الثالث من مدة الحمل اذ تتصف هذه الاصابة بارتفاع ضغط الدم وظهور بروتين الالبومين في الادرار. وقد ظلت اسباب نشوء هذه الحالة غير واضحة المعالم, اذ اعزيت بعض من اسبابها الى ا | Preeclampsia is considered as one of the serious complication in the third trimester of pregnancy. It is associated with hypertension and proteinuria. The causes of preeclamptic are still not well understood. Evidences suggested the involvement of metabolic related mutations in the disease. In the current study, the genetic mutations of CBS and MTHFR genes are studied as markers for the diagnosis of preeclampsia. Sixty preeclamptic pregnant women and forty healthy pregnant women as control group diagnosed by the physicians at Azzahra Teaching hospital for obstetrics &pediatrics in Najaf province from December 2012 to August 2013 The poly merase chain reactions technique was used to evaluate the incidence and frequency of C?S &MTHFR mutations. A questionnaire was conducted to obtain the information of the patients and the control group. Genetic mutation were detected by polymerase chain reaction (PCR)and agaros gel electrophoresis. The information indicated that the age of pregnant women, gestation age, previous history of the patients, family history and parity are involved in the pathogenesis of preeclampsia. The results of the present study of preeclampsia showed a significant increase (P ? 0.01) in patients (25 - 34) years old when compared with the other group. where the results found a significant increase (P <0.01) of Preeclampsia occurred during (33 - 39) weeks of pregnancy. And in the patients with previous history for preeclampsia there was significant increase (P<0.001) compared with healthy pregnants. Pregnants with preeclampsia in the family history showed significant increase (P< 0.01) as for women pregnant for the first time showed and significant (P<0.01) and constituted 8% pregnanst with preeclampsia who had diabetes mellitus. The extraction and quantification of cell free fetal DNA (cff DNA) revealed a significant (P<0.0001)increase in preeclamptic patients when compared with those of healthy pregnant women. It is confirmed by the use of an internal negative control through the monitoring of SRY gene (Y chromosome gene) amplification that the gene belong to the infant and 40 pregnant woman were followed up till the labor. Thus, 9 of them had delivered males, while 30 had delivered females. The wild type SRY gene band was obtained clearly from those of male delivery, but not from those of female delivery. Mutations of C?S gene were analyzed by theuse a primer intended to amplify a fragment of171 bp.The rate of mutation was found to be 51.7% and 5% in preeclamptic patients and healthy pregnant women respectively and Odd Ratio=20.31, P value=10 - 7. The C677T mutation of MTHFR gene was verified by the use of a primer designed to amplify a fragment of 198bp. The prevalence of mutation was indicated to be 68.3% and 17.5% in the preeclamptic patients and healthy pregnant women respectively and Odd Ratio =10.17, Pvalue =6.2*10 - 7. Results demonstrated the wide involvement of C?S and MTHFR gene mutation in the pathogenesis of preeclampsia, but they are no crucial for the development of the disease. In addition there are so many factors thatmay be involved in such development.

تقييم مستوى الثرومبوسبوندين لدى مرضى السكري النوع الثاني == Assessment of Thrombospondin Level In Diabetic Patients Type II

Author name: وجدان راجح حمزة الكريطي

Supervisor name: ارشد نوري غني الدجيلي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

Abstract: The present study is intended to asses serum levels of Thrombospondin - 1, Fasting blood glucose, Glycated Hemoglobin A1c, Lipid profile and BMI in type 2 diabetic patients, also correlation between Thrombospondin - 1 with all criteria above in both males and females.The study was conducted on randomly selected 65 type 2 diabetic patients (34 males and 31 females) attending the diabetes mellitus center in Al - Sadder Teaching City in Al - Najaf province, Iraq and a group of 24 apparently healthy subjects (12 Males and 12 Females) were included as a control group. The Study was carried out from August 2013 to February 2014.The patients' age was ranging of 35 to 64 years old.The results indicated a significant increase (p<0.05) in serum FBG, Cholesterol, TG, VLDL - C, LDL - C, TSP - 1 levels and a significant decrease (p>0.05) in serum HDL - C level in diabetic patients in comparing with healthy groups. The results also revealed that significant increase (p<0.05) in serum HbA1c level and BMI in diabetic patients in comparing with healthy groups.The results also revealed no significant differences (p> 0.05) in serum Cholesterol, Triglyceride, VLDL - C, LDL - C, HDL - C and TSP - 1 levels between males and females in both patients and health groups, while the results of FBG and HbA1c levels increase significantly (p<0.05) in females than males in both patients and health groups.The results show that Cholesterol, Triglyceride, VLDL - C, LDL - C, TSP - 1, FBG and HbA1c levels increase significantly (p<0.05) in both males and females patients groups in comparing with males and females of healthy groups respectively, and a significant decrease (p<0.05) in serum HDL - C in both males and females patients groups in comparing with males and females of healthy groups respectively.The results indicated a significant increase (p<0.05) in serum TSP - 1 level in females than males patients at same BMI (over weight and obese) except normal weight there is no significant differences (p>0.05) and there is no significant differences (p>0.05) between males and female of control groups at same BMI.The results show that TSP - 1 increase significantly (p<0.05) with increasing age of patients in males and females patients and the ages (55 - 64y) are highly significant(p<0.05) than (45 - 54y) and (35 - 44y), But there is no significant differences (p>0.05) in males and females of healthy groups at different ages. while there is a significant increase (p<0.05) in serum TSP - 1 level at same ages in both males and females patients in comparing with males and females of healthy groups respectively. The results also indicated that TSP - 1 increasing significantly (p<0.05) with increasing duration of disease in males and females patients and the (11 - 15y) reveals a highly significantly (P<0.05) than (6 - 10y) and (1 - 5y). The results have been shown significant positive correlation (P<0.05) between TSP - 1 and FBG, TSP - 1 and HbA1c, TSP - 1 and BMI, TSP - 1 and cholesterol, TSP - 1 and TG, TSP - 1 and LDL - C, TSP - 1 and VLDL - C in (males and females), males, females DM patients. The results have been shown significant negative correlation (P<0.05) between TSP - 1 and HDL - C in (males and females), males, females DM patients. The present study concluded that Thrombospondin - 1 and HbA1c levels were markers for detection and diagnosis of diabetic patients type

تاثير محرضات القند في وظائف الجهاز التناسلي الانثوي للفئران البيض == Effect of Gonadotrophins on Functions of Albino Mice Female Reproductive System

Author name: سعاد محمد جودة الحسناوي

Supervisor name: يحيى كاظم السلطاني

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير مستخلص بذور الحبة السوداء Nigella sativa L. في خصوبة ذكور الفئران البيض وبعض معايير الدم الفسلجية == Effect of Nigella sativa L. Seeds Extracts on the Fertility of Male Albino Mice and Some Haematological Parameters

Author name: اخلاص علي حسين الهلالي

Supervisor name: اسماعيل كاظم عجام | يحيى كاظم السلطاني

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

انتاج مبيد حيوي من لقاح الفطر Beauveria bassiana (Balsamo) Vuillemin لمكافحة حشرة من الخوخ الاخضرMyzus persicae (Sulzer) == The production of bio – cidal from inoculum of fungus Beauveria bassiana (Balsamo) Vuillemin to control the green peach aphid Myzus persicae ( Sulzer )

Author name: نبيل سليم سعيد تويج

Supervisor name: سامي عبد الرضا الجميلي | هادي مزعل الربيعي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تقييم بعض المؤشرات الحيوية لدى الاطفال حديثي الولادة المصابين باليرقان الوليدي ومضاعفاته == Evaluation Of Some Biomarkers In Neonatal Jaundice Associated With It's Complication

Author name: سارة علي ناصر الجزائري

Supervisor name: محمد عماد منصور الغرابي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

تقييم عامل النخر الورمي- الفا و انترليوكين 6 في مرضى التهاب الكبد الفيروسي-سي مع السكري وبدونه == Evaluation Of Tumor Necrosis Factor - Alpha And Interleukin - 6 In Hepatitis C Virus With Diabetes Mellitus And Non Diabetes Mellitus Patients

Author name: ضحى حيدر عبد الجواد العبود

Supervisor name: موسى نعمة مزهر الجعفيري

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

تاثير مستخلصي المائي والايثانول لجذور نبات Salvadora persica على خصوبة اناث الجرذان البيض == Effect Of Aqueous And Ethanol Extracts Of Salvadora Persica Roots On The Fertility Of Female Albino Rats

Author name: ظفر نجم عبد الشيباني

Supervisor name: ارشد نوري غني الدجيلي | جبار عبادي محمد العارضي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

تقييم مستوى الاوستيوكالسين وبعض الدلائل الاخرى لدى مرضى السكري النوع الثاني == Assessment Of Serum Osteocalcin Level And Some Other Parameters In Type 2 Diabetic Patients

Author name: هديل حيدر صالح الدجيلي

Supervisor name: ارشد نوري غني الدجيلي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

دراسات نسجية فسلجية للغدد الدهنية وعلاقتها بالاستجابة للفرمونات في الفار الابيض == Histophysiological Studies Of Preputial Gland Related To Pheromonal Response In Albino Mice

Author name: علي عادل مجيد الفتلاوي

Supervisor name: مرزه حمزه حميدي المرشدي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

دراسة جزيئية وفسيولوجية لمرض الكلية متعددة الاكياس السائد الجسمي في البالغين في محافظة النجف == Molecular And Physiological Study Of Autosomal Dominant Polycystic Kidney Disease (ADPKD) In Adults In Al - Najaf Province

Author name: رافع شاكر عبود الخفاجي

Supervisor name: علي حمود السعدي | حيدر كامل زيدان

General topic: Biology

Specific topic: Zoology

Degree: Doctorate

University: University of Kufa - College Of Science - Department Of Biology

Language: English

University location: Najaf

First pages:

دراسة العلاقة بين فقر الدم وهرمون الارثروبويتين لدى مرضى العجز الكلوي المزمن في محافظة النجف الاشرف == A study of the relationship between anemia and Erythropoietin hormone in patients with Chronic renal Failure in the Holy Governorate of Najaf

Author name: وفاء هادي موسى جواد الهاشمي

Supervisor name: عبد الزهرة كاظم محمد علي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير الحامض الدهني غير المشبع الاوميغا - 3 في بعض المعايير الهرمونية والكيموحيوية والنسجية في الارانب البيض المعاملة بعقار السايكلوسبورين == Effect of unsaturated fatty acid Omega-3 on some Hormonal, biochemical and Histological criteria in White rabbits administrated with cyclosporine drug

Author name: مرتضى محمد جواد الخفاجي

Supervisor name: ارشد نوري الدجيلي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

علاقة الارثروبيوتين ببعض المتغيرات الحيوية ذات العلاقة باعتلال الكلى السكري لدى الرجال == The relevance of Erythropoietin with Diabetic Nephropathy Related Parameters in Men

Author name: اسراء مهدي عبد الهادي زاهد

Supervisor name: سحر محمود جواد الجمالي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Education For Girls - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير المستخلص المائي والكحولي لاوراق نبات الميرمية "Salvia officinalis L." في الجرذان البيض المصابة تجريبيا بداء السكري == Effect of Aqueous and Alcoholic Extracts of Sage "Salvia officinalis L." Plant Leaves in Experimental Infected Albino Rats with Diabetes

Author name: كرار عباس تكي الخفاجي

Supervisor name: كريم طالب خشان الحاتمي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

دراسة نسجية مقارنة للفصوص اللامسية في دماغ عاملات وذكور نحل العسل Apis mellifera L. (Hymenoptera : Apidae) == Histological Comparative Study of the Antennal Lobes in the Brain of the Drones and Workers of Honeybee Apis mellifera L. (Hymenoptera : Apidae)

Author name: مريم محمد برهان الجبوري

Supervisor name: محسن حميدي الغزي | سعدي محمد هلال

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

دراسة كيموحيوية ومناعية عن تاثير بذور الحبة السوداء Nigella sativa L. في مرضى الداء السكري == Biochemical and Immunological Study of Effect of Nigella sativa L. on Diabetic Patients

Author name: رند محمد عبد الحسين الحسيني

Supervisor name: خليل ابراهيم الطيف | فارس عبد الكريم خزعل

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير مستخلص الكحول الاثيلي لثلاثة نباتات وعقاري السايمتدين والالبيندازول في داء الاكياس العدرية == Effect Of Ethyl Alcohol Extract Of Three Plants,Cimetidine And Albendazole Drugs In Hydatid Cysts Disease

Author name: شيماء عبد الحسين محمد شلاش

Supervisor name: شاكر شناوة صالح

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير التهاب المفاصل في بعض معايير الدم لدى النساء في محافظة النجف الاشرف == Effect of arithritis on some blood criteria in women in Najaf governorate

Author name: اسراء حرجان محسن

Supervisor name: ارشد نوري الدجيلي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير التدرن الرئوي ونظام العلاج قصير الامد في بعض المعايير الهرمونية والكيموحيوية لدى الرجال في محافظة النجف الاشرف == the effects of pulmonary tuberculosis and short course therapy on some hormonal and biochemical criteria of men in al_najaf province

Author name: عقيل موسى دنانة البديري

Supervisor name: ارشد نوري الدجيلي

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

دراسة الاضطرابات الهرمونية والكيموحيوية في مصل نساء محافظة النجف اللاتي يعانين من حالة تاخر الحمل بعد ترك حبوب منع الحمل الفموية == Study of Hormonal and Biochemical Disturbances in Blood Serum of Women in Najaf City Who Were Suffering from Delay in Their Pregnancy After Discontinue of Oral Contraceptive

Author name: انتصار رزاق محمد شربة

Supervisor name: عبد الزهرة كاظم

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Science - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير محلول القهوة المائي في معالم النطف لدى ذكور الجرذان البيض

Author name: هشام قاسم محمد النويني

Supervisor name: يحيى كاظم محمد السلطاني

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Education For Girls - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

علاقة الربو القصبي بمجاميع الدم (ABO) في مجتمع محافظة النجف الاشرف == The Association of Bronchial Asthma to (ABO) Blood Groups in Najaf Governorate Population

Author name: صادق محمد علي عبد الامير الترجمان

Supervisor name: يسار محمد حسن الشماع

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Education For Girls - Department Of Biology

Language: Arabic

University location: Najaf

First pages:

تاثير المحلول المائي للقهوة في الجهاز التناسلي الانثوي للفئران البيض == Effect of Coffee on The Female Reproductive System of Albino Mice

Author name: جنان مهدي غني خليفة

Supervisor name: يحيى كاظم السلطاني

General topic: Biology

Specific topic: Zoology

Degree: Master

University: University of Kufa - College Of Education For Girls - Department Of Biology

Language: Arabic

University location: Najaf

First pages: