Search — Iraqi Digital Repository

Search results: 20 out of 20

التاثيرات التشويهية لعقار الفيناتون على اجنة الجرذان : دراسة داخل الرحم وفي انابيب الاختبار == The Teratogenic Effects Of Phenytion In The Rat : An In Vivo And In Vitro Study

Author name: فاضل علي وصفي

Supervisor name: سلمان سلمان | ليث الالوسي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

تاثيرات عقار كلوريرمازين هايدروكلورايد التنويهية : دراسة داخل الرحم في انابيب الاختيار == Chlorpromazine Hydrochloride Teratogensis An In Vivo In Vitro Study

Author name: فلاح ذياب الصباغ

Supervisor name: ليث الالوسي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

تاثيرات زيادة لنحاس على الجرذان الحوامل وذريتها : دراسة نسيجية وللتشوهات الخلقيه == The Effects Of Copper Loading On Pregnant Rats And Their Offsprings : A Histological And Teratological Study

Author name: داود سالم حداد

Supervisor name: عائدة كانتارجيان | ليث الالوسي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة كمية نسيجية للب الغدة الكظرية في ذكور الجرذان الطبيعية والمعرضه للاجهاد == Quantitative Histological Study Of The Adrenal Medulla In Normal And Stressed Male Rats

Author name: عماد غانم شكري

Supervisor name: الخطيب

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

Molecular Bilology Of Normal Mammary Tissue

Author name: احمد فاخر حميد

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

University location: Baghdad

Hiuman Neural Stem Cell Culture

Author name: عبد الجبار فالح حسين

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

University location: Baghdad

ظهور مؤشرات الخلايا الجذعية في النسيج الطبيعي المجاور CD44, ALDH1A1 وCD166 لسرطان القولون والمستقيم في عينات من المرضى العراقيين == Expression of Stem Cell Markers CD44, ALDH1A1 and CD166 in Normal Tissue Adjacent to Colorectal Carcinoma in Samples of Iraqi Patients

Author name: نوال مصطفى عبد الله

Supervisor name: مصطفى محمد ابراهيم | باسم شهاب احمد

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

اظهار تعبير المؤشرين في عينات من الغدة الدرقية الطبيعية مقارنة مع عينات من الغدد الدرقية المجوثرة == Expression ofHIF-1?&HIF-2?inTissuesof NormalThyroidComparedtoTissuesofThyroid Multinodular Goitres

Author name: محمد حسين عاصي

Supervisor name: سامية عباس عليوي | باسم شهاب احمد

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة الاحياء الجزيئية لنسيج الثدي الطبيعي المحيط بمنطقة السرطان للنساء العراقيات عن طريق التهجين الموقعي للمؤشرات ERBB2, TOP2A and C-MYC وعلاقتها بوجود == MOLECULAR BIOLOGY OF NORMAL MAMMARY TISSUE SURROUNDING BREAST CA OF IRAQI WOMEN THROUGH GENETICALLY FLUERESCENT IN SITU HYBRIDIZATION OF ERBB2, TOP2A AND CMYC IN RELATION TO ER & PR

Author name: حمد فاخر حميد

Supervisor name: مصطفى محمد ابراهيم

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة نسيجية لجلد اناث وذكور الفئران بعد اعطاء عقار الكلوكوزامين سلفيت == Histological Study On The Male And Female Mice's Skin After The Administration Of Glucosamine Sulphate

Author name: معن ماجد صالح السامرائي

Supervisor name: عبد الامير حمادي النعيمي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

Abstract: يتكون الجلد وكما هو معروف جيدا من عدة طبقات من الخلايا متجددة باستمرار عبر اعادة بناء نفسها ذاتيا مرة كل ثلاثون يوما من خلال دورة حيلتية متكررة وتقسم هذه الطبقات الى نوعين اساسية البشرة والادمة. يعتبر الكلوكوز امين سكر اميني بسيط ينبعث من عمليات الايض ال | It is well known that the skin is made up of multiple layers of cells that fare constantly going through self shedding and regeneration once every 30 days, or so in repeated cycles. The layers can be broadly divided into two sections : the epidermis and the underlying dermis. Glucosamine is an amino monosaccharide derived from cellular glucose metabolism. Glucosamine is a simple component or "building block" of more complex molecules. Glucosamine was considered to be an effective treatment for many joint diseases especially osteoarthritis. It is believed that glucosamine maintain healthy joint functions and rebuild damaged joint cartilage, tendons, ligaments and other connective tissue. It does this by stimulating the production of glycosaminoglycans (GAG’s) which are the structural components of cartilage and connective tissue else where in the body. On that basis, this study was designed to study the effects of glucosamine sulphate on the skin.Twenty male and twenty females adult mice (weighting between 23.3gm to 27.2gm), were divided into two equal subgroups (control and experimental); the drug was given at noon three hours after starvation it had been grinded and mixed with food and given as a single oral dose of 350mg/kg body weight per day for 35 successive days. Histological examination and statistical analysis of multiple sections of ventral and dorsal skin of male and female mice and of both subgroups were done by using hemotoxyline and eosin stain. Special stains were used to demonstrate the specific components of the skin as follows : for collagen fibers (Van Gieson's staining method), for elastic fibers (modified Taenzer - Unna Orcien staining method), and for ground substance (Alcian blue stain method).The results reveal that there was no particular change in the epidermis between the experimental and control groups. On the contrary there was a marked thickening with high cellular contents of both layers of the dermis (papillary and reticular).The dermis of the treated animals contains more collagen and elastic fibers. The predominant cell of the dermis was the fibroblast which was more obviously seen in the ventral skin of the treated animals. This study confirms practically that glucosamine sulphate induces significant structural changes in the skin of male and female mice. Using glucosamine sulphate clinically for medical conditions rather than arthritic diseases is now the target of most recent researches, its ability to decrease wrinkles in the aged skin and promotion of wound healing with less scar tissue is consider to be a light for dermatologist and plastic doctors, plus its effect to rebuild any aged, injured and diseased tissue in the body.

دراسة تاثير اديبونكتين على هيكل كبد الفئران وعلاقته بالنظام الغذائي وكمية الدهون في الجسم == A Study Of Adiponectin Effects On The Mice Liver Architecture In Relation To Dietary Intake And Body Fat Content

Author name: غسان علي عبد الحسین

Supervisor name: سلمان شفیق سلمان | عماد غانم قاسم

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

Abstract: يعتبر مرض الكبد الدهني غير الكحولي الاضطراب المزمن الاكثر شيوعا في الكبد واصبح تشخيصه في ازدياد مع زيادة وباء السمنة العالمي وقد تم تصميم الدراسة الحالية لدراسة الفوائد المحتملة للاديبونيكتين على النماذج الحيوانية من مرض.تم تطوير نموذجين من اضطراب الكبد | Non - alcoholic fatty liver disease is the most common chronic liver disorder whose prevalence has been on the rise with the worldwide increasing pandemic of obesity. The current study was designed to study potential benefits of the adipokine (adiponectin) on animal models of non - alcoholic fatty liver disease.Two models of the disorder were developed using two different approaches. In experiment 1 (25 mice, last 8 weeks), fatty change was induced using high fructose intake to simulate human - like diet induced obesity and fatty liver disease. In experiment 2 (25 mice, last 3 weeks), fatty liver damage was induced by using methionine - choline deficient diet. Animal body weights, absolute and relative liver weight, food consumption and fructose water consumption were recorded. Visceral (epididymal) fat and liver tissue were studied using routine hematoxylin and eosin staining and histochemical stains including Masson trichrome, Periodic acid schiff and reticulin stains. Morphological and morphometric changes were compared between animals treated with adiponectin, untreated diseased animals, and control healthy animals and a non - alcoholic steatosis activity score was used to evaluate the severity of liver damage. Random blood sugar and serum lipid levels were also included as biochemical metabolic parameters.High fructose intake resulted in larger visceral fat depots and weight gain, effects that were combated by adiponectin treatment despite increased food intake. Hepatic steatosis, inflammation, pyknotic pictures and fibrosis were reduced in adiponectin treated animals resulting in a lower activity score. Random blood sugar levels were normal in all animal groups but were significantly lower in adiponectin treated groups. TG and VLDL were alleviated with adiponectin treatment.Methionine - choline deficient diet resulted in emaciation of animals, much reduced visceral fat depots but a more severe form of liver fatty damage over a shorter period of time when compared to high fructose obese animal models. Weight loss was worsened after adiponectin treatment. Hepatic steatosis, inflammatory foci, ballooning degeneration and fibrosis were all exaggerated but remained significantly less severe with less activity score in adiponectin treated animals. Random blood sugar levels were normal in all animal groups but were significantly higher after adiponectin treatment. TG and VLDL was alleviated with adiponectin treatment.Adiponectin affects appetite, food consumption and body composition in healthy animals and animal models of non - alcoholic fatty liver disease through different mechanisms. It has beneficial effects in reducing body weight in obese animals but can modulate weight loss in lean animals on methionine - choline deficient diet. Adiponectin has autocrine/paracrine effects on visceral adipose tissue and can correct the dyslipidemic picture of fatty liver disease. The antisteatotic and antifibrotic effects of adiponectin carry greater therapeutic potentials in obesity - related liver disease.

هرمون اللبتين والاستقلاب : دراسة كيميانسيجية وكيمياحيوية شاملة في الحيوانات الطبيعية والمصابة بالسكري == Leptin And The Metabolism : A Comprehensive Histochemical And Biochemical Study In Healthy And Diabetic Animals

Author name: سامح سمیر موسى عكیلة

Supervisor name: سلمان شفیق سلمان | سامیة عباس علیوي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Doctorate

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

Abstract: The adipocytokine leptin is a major player in the pathogenesis of diabetes mellitus and obesity. Since its discovery around 20 years ago, leptin has been; and still is; the subject of extensive research.The current study was designed to examine the effects of physiological doses of leptin on major organs involved in metabolism. The anatomical, histochemical, physiological, and biochemical effects of leptin were studied in healthy animals and in animal models of type 1 and type 2 diabetes.Eighty male albino mice were divided into three groups. The first group (A) consisted of healthy non - obese non - diabetic animals, a subgroup (A1) of which received leptin therapy to study its effects under normal conditions without metabolic disturbances. In the second group (B), a model of diet induced obesity and insulin resistance was developed using a combination of high fat diet and low dose streptozocin injection. In one subgroup (B1), the effects of leptin were studied under dietary manipulation after the discontinuation of high fat diet. In other subgroups, leptin effects were examined with continuous HFD with (B3) and without (B2) concomitant metformin therapy. The third group animals (C) represented a type 1 DM model developed by high dose streptozocin injection. A subgroup (C3) served as model control, not receiving any hormonal therapy. The others two subgroups received leptin treatment with (C2) and without (C1) concomitant insulin therapy.Statistical parameters for the study included the body weight, food and caloric consumption, adiposity index and specific organ weights and weight ratios. The epididymal fat pad, liver and pancreas were examined for gross anatomical and histological changes. Adipose tissue and some pancreatic sections were stained with H&E, liver sections were stained with periodic acid schiff stain, other pancreatic sections were stained with modified Gomori's aldehyde fuchsin. Random blood sugar and serum lipid levels and insulin tolerance test were also studied as biochemical parameters.Leptin therapy in healthy non - obese animals resulted in a reduction in food consumption, body weight, adiposity index and white fat pads weight. It also caused a reduction in the diameter and surface area of epididymal adipocytes. Serum TGL and LDL levels were significantly reduced. iiiThe same effects were seen in group B animals that underwent dieting or received metformin, but not in ones receiving leptin alone. Animal models of type 1 DM showed a moderate response to leptin therapy alone but the response was dramatically enhanced when treatment was combined with insulin. Sever weight loss and polyphagia of type 1 DM were greatly ameliorated by leptin therapy and there was an improvement in fat pad weights and adipocyte measurements. The hepatic glycogen content and insulin sensitivity were greater in animals treated with leptin (A1), on diet and leptin (B1) or metformin (B3) and in animals on leptin with insulin (C1). This was associated with significantly lower levels of random blood sugar. The pancreatic islet surface area was markedly reduced while the ? - cell/ ? - cell ratio was increased in treated animals.Leptin therapy can alter body weight and adiposity index by affecting appetite and food consumption via central and peripheral mechanisms involving the control of feeding behavior and manipulating the processes involved in carbohydrate and lipid metabolism. It can also correct the metabolic disturbances of type 2 DM but requires the concomitant use of metformin and/or the manipulation of dietary content of fat and carbohydrates. Much of its influence arises from its ability to enhance insulin sensitivity.Leptin also has a sparing effect on hepatic glycogen, favoring in turn the use of fatty acids for energy expenditure. Leptin effects on blood glucose are insulin dependent in most cases but can be insulin - independent in type 1 DM by utilizing alternative metabolic pathways for energy expenditure and interacting with hyperglycemia - inducing hormones.

ظهور المؤشرات في الثدي الطبيعي المحيط بسرطان الثدي في عينة من النساء العراقيات

Author name: احمد فاخر حميد

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

تاثير اثنيل استرادايول وخلات سايبروتيرون على جلد ومبيض اناث الفئران البيضاء : دراسة نسيجية وقياس شكلية == The Effects Of Ethinyl Estradiol & Cyproterone Acetate, On Skin And Ovary Of Female Albino Mice : A Histological And Morphometeric Study

Author name: نبراس حاتم خميس

Supervisor name: امل علي الخطيب | انصاف جاسم الحسون

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة نسجية لكلية ذكور الجرذ بعد اعطاء هرمون الميلاتونين == Histological Study On Male Rat’s Kidney After Administration Of Exogenous Melatonin

Author name: مصطفى محمد ابراهيم

Supervisor name: امل علي الخطيب | عبد الامير حمادي النعيمي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

التغييرات النسيجية والقياس شكلية للمشيمة وعلاقتها بقياس ابغار الواطئ والعالي == Histological And Morphometric Changes In The Placenta In Relation To Low And High Apgar Score

Author name: محمد عماد غانم

Supervisor name: سامية عباس عليوي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

مانع الحمل الهرموني الذكري : دراسة نسيجية وشكلية لخصى الفئران البيض == Hormonal Male Contraception, Histological And Morphometrical Studies On Albino Mice Testes

Author name: عبد الجبار فالح حسين

Supervisor name: امل علي الخطيب

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة نيسجية والنقص الاقراص بين الفقرات لقطنية == Histological And Magnetic Resonance Imaging Study Of Lumbar Intervertebral Disc Degeneration

Author name: حیدر حامد عبد اللطیف

Supervisor name: عماد غانم شكري | حیدر قطران رحیم

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

التغيرات النسيجية المستحثة بفعل هرمون النمو البشري في غدة التوتة للفئران البيض == Histological Changes Induced By Exogenous Human Growth Hormone In The Thymus Of Male Albino Mice

Author name: سامح سمير موسى صالح عكيلة

Supervisor name: سلمان شفيق سلمان

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

تاثيرات الجرعات المنشطة لمادة كلين بيوتيرول هايدروكلورايد على خصى الفئران البيضاء : دراسة نسيجية == Effects Of Anabolic Doses Of Clenbuterol Hydrochloride On Albino Mice Testes : Histological Study

Author name: زياد صباح عزيز

Supervisor name: زينب احمد كاظم شيرازي

General topic: Medicine

Specific topic: Anatomy and Histology and Embryos

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages: