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دراسة نظرية طيفية لبعض مشتقات الثايوفين == Theoretical Spectroscopic study for some Thiophene derivatives

اسم المؤلف: نمارق عامر لفته
اسم المشرف: شذى فاضل السعيدي
الموضوع العام: علوم الكيمياء
السنة: 2018
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد

تاثير بعض المعادن الثقيلة على وظائف الغدة الدرقية == Impact of Some heavy metals on thyroid gland functions

اسم المؤلف: سارة جواد كاظم
اسم المشرف: علاء حسين جواد
الموضوع العام: علوم الكيمياء
السنة: 2018
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بغداد

تحضير وتشخيص مركبات حلقية غير متجانسة من مشتقات الفانيلين == Synthesis and Characterization of Heterocyclic Compounds from Vanillin Derivatives

اسم المؤلف: مراد كدر مناحي نويف
اسم المشرف: خضير جواد كاظم
الموضوع العام: علوم الكيمياء
السنة: 2018
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بابل

دراسة نمذجة جزيئية لعقار الجنتاميسين وبعض مشتقاته الجديدة == Molecular Modeling Study of Gentamicin Drug and Some of Its New Deriv

اسم المؤلف: مروة كامل جليل احمد
اسم المشرف: عباس عبد علي دريع الصالحي
الموضوع العام: علوم الكيمياء
السنة: 2018
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بابل

طريقة طيفية جديدة لتقدير ايونات النحاس II والحديد III باستخدام المركبات الدوائية الاموكسيسلين صوديوم والسيفيكزيم ثلاثي الهيدرات == New Spectrophotometric Method for the Determination of Cu(II) and Fe(III) using Drug Compounds(Amoxicillin - Sodium and Cefixime Trihydrate)

اسم المؤلف: علي سعدون ناجي دحام
اسم المشرف: عباس نور الشريفي
الموضوع العام: علوم الكيمياء
السنة: 2018
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: الانكليزية
مكان الجامعة: بابل
المستخلص: This thesis consists of three methods : | Describes three simple and sensitive methods for the determination of copper (II), iron (III) ions and Cefixime trihydrate drug. | The first method based on determination of copper ion in aqueous so-lution, in its pure form, pharmaceutical preparations and in fungicide sam-ples, by oxidizing phenol group in Amoxicillin drug in oxidative coupling reactions, coupled of two molecules of Amoxicillin, these oxidized by cop-per (II) ion as oxidized agent in alkaline medium pH 11.5 to give a violet coloured product, soluble in water, has maximum absorption at wave-length (540) nm at 30 ᵒC. Beer's law was obeyed between (5-32) μg.ml-1, a molar absorptivity (5× 104) L.mol-1cm-1, Sandell's sensitivity (0.12)μg cm-2, the LOD was (0.29) μg.ml-1 , LOQ was (0.97) μg.ml-1. | The second method includes determination of iron (III) depends on reduced iron (III) to iron (II) by Cefixime trihydrate as reducing agent, the iron (II) react with three molecules bipyridyl to form red coloured product complex, soluble in distilled water in acidic medium PH 3.3 that has max-imum absorption at wavelength 520 nm. Beer's law was obeyed between (0.5-11) μg.ml-1, a molar absorptivity (1.02 × 104) L.mol-1.cm-1, Sandell's sensitivity (5.49 ×10-3) μg.cm-2, the LOD was (0.013) μg.ml-1, LOQ was (0.045) μg.ml-1. This method was applied successfully for the determina-tion of iron (III) in pure state and in pharmaceutical formulations (Tablets, Syrup), the analytical results were compared with the standard method was used for determination of iron (III), | The third method has been described a reversible determination of Cefixime trihydrate based on the same above second method, the iron (III) as oxidizing agent in acidic medium, under the same optimum conditions at wavelength (520) nm. Beer's law was obeyed between (1-18) μg.ml-1, a | molar absorptivity (5.55 × 103) L.mol-1.cm-1, Sandell's sensitivity (1.01×10-2) μg.cm-2, the LOD was (0.032) μg.ml-1, LOQ was (0.106) μg.ml-1. This method was applied successfully for the determination of (CEFI) in phar-maceutical formulations (Tablets and Syrup). | Evaluating the proposed methods results by using F and t- test. It was found that results experimental F and t value at 95% confidence level did not exceed the critical values. This means the proposed methods have no different significally in accuracy and precision with standard method. The effect of interference ions (Mn(II), Co(II), Ni(II), Zn(II), Ag(II), Hg(I), Cd(II), pb(II)) on copper(II), and iron(III) also has been studied.

تحضير وتشخيص ودراسة الفعالية البايولوجية لمشتقات جديدة من 4.3.1 اوكسادايازول ومعقداتها مع بعض العناصر الانتقالية == Preparation , characterization and biological activity of a new1,3,4 - oxadiazole derivatives and some of their transition metal complexes

اسم المؤلف: ايمان حسين شويل التميمي
اسم المشرف: ابراهيم عبود فليفل | احمد حسن محمد
الموضوع العام: علوم الكيمياء
السنة: 2018
الموضوع الدقيق: الكيمياء
الدرجة: ماجستير
اللغة: العربية
مكان الجامعة: ذي قار
المستخلص: The work described in this thesis is mainly concerned with preparation and characterization of three ligands (L1-L3) derived from 1,3,4-Oxadiazole .The study deals with reaction of these ligands with transition metal salts as (CrCl3.6H2O , CoCl2.6H2O , NiCl2.6H2O , CuCl2.2H2O) .The ligands and their complexes were characterized by the elemental analysis (C,H,N), Infrared spectroscopy (IR) , Proton Nuclear Magnetic Resonance Spectroscopy (1HNMR), Mass spectra and molar conductivity. However, the ligands and some of their were studied by using hyperchem7.5 program in order to know their geometry and proving their shapes and hypridizaion which were notice the chromium complexes is octahedral (oh), the hypridization is d2sp3 with the three ligands while the shapes of the complexes (cobalt(II), Nickel(II), Cupper (II) ) is four coor-dinated is square planar and the hypridizaion is sp3. | Antibacterial activity was carried out against Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes and Klepsiella pneumonia, and with test compounds at four concentrations of (5, 2.5, 1.25, 0.625mg/ml). Azithromycin and Cefoaxime were the standard drugs utilize. Some of these compounds showed good efficacy, while others ranged from medium to small. | The hemolysis activity of the compounds was tested at different concentrations (5, 2.5, 1.25, 0.625mg/ml) and the results showed high percentage of hemolysis for all these compounds and these gave a conclusion about the contraindication use of these compounds in vivo .
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