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المؤشر الورمي CA153 عناصر مختارة في اللعاب وعلاقتها بصحة الفم والاسنان ضمن مجموعة من النساء العراقيات المصابات بسرطان الثدي == Salivary Tumor Marker CA15 - 3 And Selected Elements In Relation To Oral Health Status Among A Group of Iraqi Breast Cancer Women

Author name: بسمة عبد الباري عزیز

Supervisor name: احلام طه محمد

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

Abstract: Background : Breast cancer is the commonest type of malignancy worldwide and in Iraq. It is a serious disease that affects the general health and cause systemic changes that affect the physical and chemical properties of saliva leading to adverse effects on oral health.Aims of the study : The aims of this study were to assess the oral health condition (including dental caries, oral cleanliness and periodontal health condition), to evaluate the changes in salivary flow rate and to assess the concentration of tumor marker CA15 - 3 and selected elements (calcium, phosphorus, zinc, copper, total proteins) in saliva and their relation to oral variables among breast cancer women in comparison to control group.Subjects, Materials and Methods : The total sample consisted of 60 women aged 35 - 45 years attending Al - Kadhemyia Teaching Hospital. Those comprised 30 women newly diagnosed with breast cancer before starting treatment and 30 women without clinical signs and symptoms of breast cancer as a control group.Diagnosis and recording o f dental caries was done by using DMFS indexaccording to the criteria of WHO (1987). Plaque index of Silness and Loe (1964) and calculus component of Ramfjod index for periodontal disease (1959) were applied to assess oral cleanliness. Periodontal disease was evaluated using the gingival index (Loe and Silness, 1963) and loss of attachment level (Ramfjord, 1959). Stimulated salivary samples were collected and salivary flow rate, salivary CA15 - 3, calcium, phosphorus, zinc, copper ions and total proteins were determined.Results : Results showed that caries experience (DMFS) was higher among the study group compared with the control group but the difference was statistically not significant. The mean values of plaque index, calculus index, gingival index and loss of attachment were higher among the study group than the control group with a highly significant difference (P<0.01).The salivary levels of CA15 - 3 in breast cancer patients were higher than that of the controls with a highly significant difference (P<0.01). All the correlations between salivary CA15 - 3 and dental caries and periodontal diseases were statistically not significant.The salivary flow rate was lower among the study group than control group with a highly significant difference (P <0.01). Higher concentrations of salivary phosphorus, copper and total proteins were recorded among study group compared to control with statistically highly significant differences concerning phosphorus and copper (P<0.01). On the other hand, salivary calcium and zinc were lower among study group compared to control group with statistically highly significant difference concerning zinc (P<0.01). All the correlations between the caries experience and salivary constituents in the study and control groups were weak and not significant except the correlation with total proteins in the control group which was significantly positive. Concerning the correlations of oral hygiene and periodontal disease with salivary constituents, the study showed that all the correlations were weak and not significant except the correlations between the total proteins with loss of attachment in study group and with dental plaque in control group which were significantly positive relations.Conclusions : This study showed that the breast cancer patients had poor oral hygiene and higher rates of periodontal diseases and dental caries, therefore special preventive programs need to be designed for this group of patients. Also the results of this study could support the concept that salivary oncentrations of CA15 - 3 might serve to be used in the detection of breast cancer and/or the po operative follow - up of patients under treatment for carcinoma of the breast

دراسة المضاعفات الفموية الوجهية, مؤشرات عامل - الغلوبيولين المناعي اللعابي A , الانترليوكين 6 وعامل تنخر الورم الفا في لعاب مرضى بيتا ثلاسيميا الكبرى في محافظة ميسان == Study of Orofacial Complications, Salivary IgA, Interleukin - 6 And Tumor Necrosis Factor - Alpha Markers In Saliva of Beta - Thalassemia Major Patients In Missan Governorate

Author name: جمال محبس ديوان

Supervisor name: زاهدة جاسم محمد

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

Abstract: الثلاسيميا نوع بيتا هو الاضطراب الاحاد اليين الاكثر شيوعا في الشرق الاوسط، والتي تتميز بشذوذ في تركيب سلاسل بيتا من خضاب الدم مما يؤد الى ظواهر متفاوتة تتراوح بين فقر الدم الشديد الى عدم وجود اعراض سريريا.اهداف الدراسة : تحديد مدى انتشار المضاعفات الفمو | Beta - thalassemia is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. Several immunological defects can be found in patients with beta - thalassemia major patients, among which circulating cytokines levels, impairment of neurophil, macrophage phagocytic and killing functions, this impairment may be due to iron over load.Aims of study : Aims of this study was to evaluate the prevalence of Orofacial complications in beta - thalassemia major patients, salivary flow rate, salivary levels of salivary immunoglobulin A, interleukin - 6 and tumor necrosis factor alpha and to evaluate correlations between salivary parameters (salivary immunoglobulin A, interleukin - 6, tumor necrosis factor alpha and salivary flow rate) in beta thalassemia major patients.Methods : Sixty subjects were participated in this study, they were divided into two groups, patients group composed of 30 patients with major beta - thalassemia, age rang (5 - 23), and 30 healthy looking subjects of both sexes as a control group, age rang (5 - 25). Data was collected using a special formula for general, medical and Orofacial examination sheet. Whole non - stimulated saliva was collected, measured and analyzed by enzyme linked immmunosorbent assay.Results : Most patients were in the first and second decade of life (90%), 20 (60%) were males and 10 (40%) were females with an age rage (5 - 23 years). The prevalence of Orofacial complications in beta - thalassemia major patients increased with age.The prevalence of orofacial complications in beta - thalassemia major patients were color change of oral mucosa (73.3%), rodent face (66.7%), maxillaryprotrusion (66.7%), saddle nose (63.3%), deep bite (26.7%)), open bite (13.3%) and spacing (10%).Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013).Laboratory investigations for salivary concentration of interleukin - 6, tumor necrosis factor alpha and salivary immunoglobulin A revealed highly significant to significantly in mean of these parameters in beta thalassemia major patients as compared with control group, interleukin - 6 (p=0.001), tumor necrosis factor alpha (p= 0.01) and salivary immunoglobulin A (p= 0.05) at P value ? 0.05.Conclusions : Beta - thalassemia major patients have specific Orofacial complications and a particular salivary cytokines compared to normal individuals.

تقييم تاثير بلازما النيتروجين المتوهج لغرسة التيتانيوم التجاري على الترابط العظمي بالتحليل الميكانيكي والتحليل النسيجي == Evaluation of The Effect of Glow Plasma Nitriding of Commercially Pure Titantium Dental Implant On Osseointigration Through Mechanical And Histomorphometric Analysis

Author name: حسن جواد فرحان المسعودي

Supervisor name: شذى سليم الامير

General topic: Dentistry

Specific topic: Dentistry

Degree: Higher Diploma

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

Abstract: الاتجاه الجديد للغرسات هوايجاد المواد التي تسرع عملية بناء العظم في السطح البيني للعظم والغرسه وتحسين الاندماج العظمي من اجل توفير التحميل الفوري والمباشر بعد وضع الغرسات وتقليص فترة الانتظار التي تكون مزعجه وغير مريحه للمرضى.الاهداف.تقييم تاثير طلاء ال | Introduction : The new trend of implants is to find materials which accelerate bone formation in bone implant interface and improve osseointegration to provide immediate or early loading after placement in addition to eliminate the waiting period which is usually uncomfortable and disturbs patients. Aim of study : To evaluate the effect of plasma nitride treatment of screw shaped commercially pure titanium dental implant on bond strength at bone implant interface by torque removal test and histomorphometric analysis after 2 and 6 weeks in comparison to non treated one.Materials and methods : Commercial pure titanium plates and screws were plasma nitrided for 10h using glow plasma nitride apparatus. X - ray diffraction (XRD) analysis , scanning electron microscope examination were carried out on the nitride surfaces of the plates ,contact angle measurement (Wettability) was done by applying drop of saline and blood on the nitrided surface and compared to control. The femur of 10 white New Zealand rabbits were chosen as implantation sites. The femur of each rabbit received two screws, one plasma nitride treated and one non treated and a total of 40 screws were implanted. Torque removal test was performed(by digital torque meter) to measure bond strength between implant and bone, after 2 and 6 weeks healing periods. For each period of time 18 screws were tested for the torque required to remove the implant from the bone and 2 screws were kept for histological examination. Results : The results revealed that the mean removal torque values for the plasma nitride treated implants was significantly higher than the non treated implants and over the two periods of time. There was an increase in the bond strength (torque value) of bone - implant interface with time. The torque removal force for plasma nitride implants after 2 and 6 weeks was (30.22, 59.56 N.cm ,respectively) and for non treated implants after 2 and 6 weeks were ( 23.61,56.11N.cm, respectively) and new bone formation ratio for plasma nitride treated implants after 2 and 6 weeks(3.36, 4.72 , respectively) and for non treated after 2 and 6 weeks(1.56, 3.04, respectively). Conclusion : Plasma nitriding of Cp Ti screws significantly increased the torque removal value and new bone formation ratio at 2 and 6 weeks compared with the non treated implant.Dental implant, Osseointegration, Digital torque meter

نقييم الالفا اميليز والكورتيزول في اللعاب كمؤشرين جيويين للتوتر النفسي وعلاقتها بامراض المفصل الصدغي بين عينة من طلاب كلية طب الاسنان == Assessment of Alpha - Amylase And Cortisol As Salivary Psychological Stress Markers In Relation To Temporomandibular Disorders Among A Sample of Dental Students

Author name: سرمد قيس علي

Supervisor name: رجاء هادي الجبوري

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

Abstract: Background : University dental students perceived a higher level of stress prior to each examation especially the final. Therefore, there is a need for a useful noninvasive biomarker for measuring acute stress in those students. Many studies considered salivary alpha - amylase as a stress biomarker that is most often used in conjunction with cortisol. Understanding of the exact association between these two salivary stress markers are poorly established. Using a Helkimo anamnestic and clinical dysfunction scoring index for temporomandibular disorders can give a better insight about the association between these markers and temporomandibular joint disorders.The aims of study : was to evaluate the levels of salivary alpha - amylase and salivary cortisol in stressed students with temporomandibular joint disorders and the differences between these markers in relation to temporomandibular joint disorders students. This might give a better understanding to the role of psychological stress as an etiological factors for developing temporomandibular joint problems.Subjects, materials and methods : A total eighty (60 study and 20 control) participants aged between 20 and 24 years, were recruited for this study. The participants were final year undergraduate Baghdad university dental students who were examined and gave saliva samples before their final academic examination. Those with temporomandibular joint disorders problems were exposed to psychological stress and included on the study. While, those who were taking corticosteroids or hormone supplementation including oral contraceptives, or having history of head injury, orthodontic treatment, occlusal disharmonies and muscle tenderness due to systemic diseases as fibromyalgia, or having more than 2 missing posterior teeth were excluded. Salivary assay kits (alpha - amylase and cortisol) were used to measure those variables and a Helkimo anamnestic and clinical dysfunction scoring for temporomandibular joint disorders were utilized in this study.Results : There is statistically a highly significant difference of the salivary cortisol and salivary alpha - amylase in the patient group( stress with temporomandibular joint disorders) and control group. The absence of correlation between these salivary markers was founded. Correlation analysis of salivary cortisol with Helkimo anamnestic and clinical dysfunction score shows positive association expressed by significant probability of error (p) value while for salivary alpha - amylase there is no association.Conclusion : This study demonstrates that salivary alpha amylase can be used as a stress biomarker in conjunction with cortisol to assess temporomandibular joint problems due to psychological stress in university students.

الظواهر الوجهية والفموية، عوامل الاكسدة ومضادات الاكسدة في مصل ولعاب مرضى فقر الدم البحر الابيض المتوسط نوع بيتا في مدينة كربلاء == Oro - Facial Manifestations, Oxidative Stress And Antioxidants Markers In Serum And Saliva of Patients With Beta Thalassemia Major In Karbala City

Author name: مؤيد صاحب عباس شمسه

Supervisor name: تغريد فاضل زيدان

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

Abstract: Thalassemia is a hereditary anemia resulting from defects in hemoglobin production. Beta Thalassemia, which is caused by a decrease in the production of beta globin chains, affects multiple organs and is ssociated with considerable morbidity and mortality. Aims of the study : The aims of this study were to study the oro - facial manifestations in beta thalassemia major patients and evaluation of the oxidative stress status in serum and saliva represented by malondialdehyde as xidative stress indicator and also assessment of serum and saliva antioxidants which are ceruloplasmin and uric acid in beta thalassemic patients with and without periodontitis and compared that with the healthy individuals in addition to investigate the relation between the clinical findings and laboratory investigations.Methods : Eighty seven (87) subjects were consented and contributed in this study, twenty eight (28) thalassemic patients with periodontitis, thirty (30) thalassemic patients without periodontitis and twenty nine (29) healthy subjects that were age matched with the patients. Oral examination has been done for each subject. Serum and saliva sample have been taken from each subject for analysis, to study malondialdehyde as oxidative stress and antioxidants ceruloplasmin and uric acid.Results : Malocclusion was the most common prevalent oro - facial manifestations (60%), followed by rodent face (35%), brown pigmentation of oral mucosa (23%) and incompetent lip (8%). The mean serum and saliva malondialdehyde were significantly higher in thalassemic patients with periodontitis than that in thalassemic patients without periodontitis and healthy subjects (p<0.001), while the mean serum and saliva ceruloplasmin were significantly higher in control group than that in other study groups (p<0.001). The mean serum uric acid was significantly higher in thalassemic patients without periodontitis than that in thalassemic patients with periodontitis and healthy subjects (p<0.001) and the mean saliva uric acid was significantly higher in thalassemic patients without periodontitis (p<0.05) compaired with thalassemic patients with periodontitis and healthy subjects. The results of this study showed that there were no significant correlation between serum and saliva malondialdehyde in any of study groups, while there was a positive significant linear correlation between serum and saliva ceruloplasmin in thalassemic patients with periodontitis (p<0.05), a negative significant linear correlation in healthy subjects (p<0.05) , a positive significant linear correlation in thalassemic patients without periodontitis (p<0.001). The results showed that there was a positive significant linear correlation between serum and saliva uric acid in thalassemic patients with periodontitis (p<0.05), a positive significant correlation in thalassemic patients without periodontitis (p<0.001) and no significant correlation between serum and saliva in healthy subjects. On the other hand there were no significant correlation between serum and saliva (malondialdehyde, ceruloplasmin and uric acid) and clinical attachment loss (p>0.05), except a positive significant linear correlation between clinical attachment loss and salivamalondialdehyde (p<0.05) was found. Conclusions : Malocclusion was the most prevalent oro - facial manifestations of beta thalassemia major patients. Oxidative stress play a significant role in the pathogenesis of beta thalassemia ,which was the main cause of red blood cells destruction represented by significant elevation of serum and saliva malondialdehyde and significant reduction of ceruloplasmin. Also oxidative stress remain contributing factor in periodontal tissue destruction, which was appeared as a significant increased level of saliva malondialdehyde and decreased saliva ceruloplasmin in patients with periodontitis and there was a significant correlation between saliva malondialdehyde and clinical attachment loss

Assessment of The Oral Findings, Salivary Oxidative Status And Iga Level Among Group of Workers Exposed To Petroleum Pollutants In Al - Daura Oil Refinery

Author name: امير سعد حمزة

Supervisor name: Jamal Noori Ahmed

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

Abstract: Petroleum is perhaps the most important substance consumed in modern society. Petroleum is unique and s a complex mixture of thousands of compounds. Oil refinery workers are continuously exposed to numerous hazardous materials and working conditions that place them at continuous risk of injury and death.Petroleum contains the heavy metals as a natural constituent or as additives. The main threats to human health from heavy metals are associated with exposure to lead, cadmium, mercury and arsenic. Several carcinogenic metals such as arsenic, cobalt, chromium, lead, mercury, and nickel induce redox reactions in living systems. These metals induce the production of reactive oxygen species in both in vivo and in vitro systems. These radicals have rendered oxidative damage to deoxyribonucleic acid, proteins, and lipids. Secretory immunoglobulin A is the main immunoglobulin found in mucous secretions from the tear glands, salivary glands, mammary glands, the respiratory system, the genito - urinary tract, and the gastrointestinal tract.Aims of the study Assessment of the salivary levels of heavy metals among the workers of Al - Daura oil refinery, assessment of the oxidative status in the oral cavity of the workers by measurement of Malondialdehyde and Superoxide dismutase markers,assessment of the oral immunological activity by measurement of secretory immunoglobulin A level in saliva and Assessment of the oral findings among the workers.Subjects, Materials and Methods This study was done in Al - Daura oil refinery, samples consist of 60 workers involved in refining processes as study group subdivided into three subgroups which represent the different sections in the refinery and 20 subjects not involved in refining processes as control group. Oral examination and saliva collection was done to assess the oral findings and measure the level of heavy metals (lead and cadmium), oxidative status (Malondialdehyde and Superoxide dismutase) and secretory IgA.Results The mean of salivary lead and cadmium was higher in study group (6.34 ?g/dl and 0.56 ?g/l respectively) than that of control group (3.3?g/dl and 0.34 ?g/l respectively) with highly significant difference (p

Evaluation Of Salivary Immunoglobulin A, Interleukins IL - 1 Alpha And IL - 8 In Psoriatic Patients With And Without Geographical Tongue

Author name: تانيا عاصم فائق

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

Evaluation Of Bleaching Effect On Microhardness And Morrphological Appearance On Enamel In Children

Author name: ندى عبد الواحد شنان

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

Language: English

University location: Baghdad

First pages:

دراسة مقارنة بين تاثير التلقيح بالمبيضات البيضاء تحت الجهاز الحنكي الاكريلي والكروم كويلتي في جرذ وسند

Author name: محمد علي كشمولة

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

حالة ما حول الاسنان عند المرضى الذين يتعاطون العقارات الغير استيرودية المانعة للالتهاب : دراسة سريرية

Author name: زينب عزيز عبد الامير

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

University location: Baghdad

تاثير ازالة طبقة الجليط على قوة ثبات وتد التيتانيوم المتوازي المسنن المثبت بالسمنت الزجاجي

Author name: جوني بطرس شمو

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Baghdad

University location: Baghdad

التحليل الهيكلي السني وانواع الوجه للبالغين العراقيين في مدينة الموصل ذوي الصنف الاول من الاطباق الطبيعي للاسنان : دراسة شعاعية جانبية لقياسات الراس

Author name: ندى محمد سعيد الصائغ

General topic: Dentistry

Specific topic: Dentistry

The Effect Of Iaser Welding On The Tensile Strength And Radiographic Analysis Of Co - Cr Rebaired Joints

Author name: عبد الله جاسم محمد النعيمي

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

He Effect Of Some Naturl Products On Disinfection And Some Physical Propties Of Wax And Acrylic Denture Base

Author name: رنا ربيع عزيز الصميدعي

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Evaluation Of Surface Roughness And Adherence Of Candia Albicans On Some Denture Base And Denture Lining Materials (An In Vitro Study)

Author name: ريم ناطق عبد القادر

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Evaluation Of Space Closure Rate , Tipping , Rotation And Vertical Assessment Of Canine During Its Retraction With Sliding Mechanics In Different Bracket Types An In Vitro Study

Author name: افنان جمال الدين اسماعيل رشيد

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Evaluation Of Microwave Disinfection And Its Effect On Some Physical Properties Of Acrylic Acrylic Resin Denture Base

Author name: الاء ناظم محمد

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Effect Of The Enamel Bleaching On The Shear Bond Strength And The Site Of Bond Failure Of Orthodontic Brackets (An In Vitro Study)

Author name: عمر خالد محمد

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Effect Of Platelet Rich Plasma And Propolis On Healing Of Bone Defects In Rabbits

Author name: ضرار احمد قاسم الجمعة

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Effect Of Glass Ionomer Cement Of The Micrdness Of Artificially Demineralized Dentin 'An In Vitro Study '

Author name: انتصار سعد الله توما القصاب

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

تاثير القصر الحي واستعمال مادة مضادة للاكسدة على التسرب المجهري للحشوة الراتنجية باوقات مختلفة : دراسة مختبرية

Author name: اسعد محمد عبد القادر

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

تاثير استخدام المعدن المعاد صبه على قابلية صب المعدن وقوة الربط الانزلاقي للخزف الملفح مع سبيكة النيكل - كروم

Author name: ايمان محمد يحيى

Supervisor name: عبد الخالق قاسم الشيخ عبدال

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

Vertification Of Electrochemical Corrosion Behavior Of Orthodontic Archwires In Artificial Saliva

Author name: حيدر موفق ياسين شندالة

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

The Influence Of Flowable Composite Resinand Bonding Agents On Gingival Marginal Microleakage In Class Ii Composite Restorations

Author name: شيماء شاكر حسن

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul

The Effect Of Curing Time And Light Intensity The Degree Of Conversion Of Poly - Acid Modified Composite On Resin

Author name: فنار تركي عبد الحميد

General topic: Dentistry

Specific topic: Dentistry

Degree: Master

University: University of Al Mosul - Faculty Of Dentistry

University location: Mosul