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دراسة مقارنة بين تاثير الاسبارتام والنيوتام الحرين والمصنعين نانويا على بعض المعلمات الفسيولوجية العصبية والكيموحيوية في ذكور الجرذان == Comparison Study between the effects of Free and newly synthesis Aspartame and neotame nanoparticles on Some Neurophysiological and biochemical markes in male rats

Author name: احمد جاسم محمد التميمي
Supervisor name: حسن كاطع العوادي | حمزة هاشم كزار
General topic: Veterinary Medicine
Specific topic: Physiology
Degree: Master
University: Al-Qasim Green University - College of Veterinary Medicine - Department of Physiology, Biochemistry and Pharmacology
Language: English
University location: Babylon

التشخيص التقليدي والجزيئي لطفيلي Entamoeba spp في الانسان والابقار في محافظة بابل == Traditinal and Molecular Detection of the Entamoeba spp. in human and cattle in Babylon Province

Author name: محمد جواد كاظم الجبوري
Supervisor name: قاسم جواد امير الجبوري
General topic: Veterinary Medicine
Specific topic: Parasites
Degree: Master
University: Al-Qasim Green University - College of Veterinary Medicine - Department of Parasitology
Language: English
University location: Babylon

علاقة تعدد الاشكال الجيني للهرمون المطلق لهرمون النمو و مرض ضخامة الاطراف للمرضى في العراق == The Association of Growth Hormone Releasing Hormone Gene Polymorphism with Acromegaly in Patients from Iraq

Author name: ذو الفقار غالب تركي
Supervisor name: ناظم مشتاق هاشم
General topic: Biology
Specific topic: Biotechnologies
Degree: Master
University: Al-Qasim Green University - College of Biotechnology - Department of Medical Biotechnology
Language: English
University location: Babylon
Key words:
  • Growth Hormone Releasing Hormone Gene
  • DNA Mutation
  • Endocrine
  • Acromegaly
  • Growth Hormone
Abstract: Acromegaly is a rare syndrome categorized by extreme excretion of growth hormone via a pituitary adenoma, happening everywhere in the world also in Iraqi population. Practically all conditions of acromegaly are produced by a benign tumor in the pituitary that creates much growth hormone. In additions, some tumors in the body may yield an element known as growth hormone releasing hormone which lead to stimulating the pituitary for over secretion of growth hormone. The main objective of study was to determine the association of GH,IGF-1,GHRH,FBS biochemical parameter as well as GHRH gene polymorphism with the severity of acromegaly disorder. The biochemical and molecular genetic study is performed from August 2022 to October 2022, including 80 samples of Iraqi ACM patients that collected from Diabetic National Center in AL-Mustansiriyah University and 40 samples from healthy . Biochemical study includes 80 samples ACM patients and 40 were as a control. The measuring of FBS by Trinder method , GH, IGF-1 were achieved by using sandwich chemiluminescence immunoassay technique and The measuring of GHRH was achieved by using the enzyme-linked immunosorbent assay (ELISA) kit to estimate the variations among these biochemical parameters in healthy and ACM patients. The genetic material (DNA) was isolated from ACM patients and healthy controls. The one fragment of GHRH gene (amplicon size 791 included exon 2,3 and intron 2) within chromosome 20 was amplified via polymerase chain reaction technique.