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Histomorphological Study Of Hematopoiesis Stages In Bone Marrow Of Adult Male Albino Rat Rattus Norvegicus

Author name: Al - Ta ae . Muntadhur Muhammad Cani
General topic: Veterinary Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - College Of Veterinary Medicine
University location: Baghdad
Key words:
  • Veterinary anatomy

Anatomical , Histological And Biochemical Study Of Remaining K Idney Ofter Unilateral Nephrectomy In Young And Adult Indigenous Rabbits Oryctola Cuniculus

Author name: al - khuzae bassim abdullah jassim
General topic: Veterinary Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - College Of Veterinary Medicine
University location: Baghdad
Key words:
  • veterinary anatomy

ظهور مؤشرات الخلايا الجذعية في النسيج الطبيعي المجاور CD44, ALDH1A1 وCD166 لسرطان القولون والمستقيم في عينات من المرضى العراقيين == Expression of Stem Cell Markers CD44, ALDH1A1 and CD166 in Normal Tissue Adjacent to Colorectal Carcinoma in Samples of Iraqi Patients

Author name: نوال مصطفى عبد الله
Supervisor name: مصطفى محمد ابراهيم | باسم شهاب احمد
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Mustansiriyah University
Language: English
University location: Baghdad
First pages:

اظهار تعبير المؤشرين في عينات من الغدة الدرقية الطبيعية مقارنة مع عينات من الغدد الدرقية المجوثرة == Expression ofHIF-1?&HIF-2?inTissuesof NormalThyroidComparedtoTissuesofThyroid Multinodular Goitres

Author name: محمد حسين عاصي
Supervisor name: سامية عباس عليوي | باسم شهاب احمد
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Mustansiriyah University
Language: English
University location: Baghdad
First pages:

دراسة الاحياء الجزيئية لنسيج الثدي الطبيعي المحيط بمنطقة السرطان للنساء العراقيات عن طريق التهجين الموقعي للمؤشرات ERBB2, TOP2A and C-MYC وعلاقتها بوجود == MOLECULAR BIOLOGY OF NORMAL MAMMARY TISSUE SURROUNDING BREAST CA OF IRAQI WOMEN THROUGH GENETICALLY FLUERESCENT IN SITU HYBRIDIZATION OF ERBB2, TOP2A AND CMYC IN RELATION TO ER & PR

Author name: حمد فاخر حميد
Supervisor name: مصطفى محمد ابراهيم
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Mustansiriyah University
Language: English
University location: Baghdad
First pages:

استخدام الصبغة المناعية p16INK4a والتهجين الموقعي وتاثيرها على فحوصات عنق الرحم الصحيحة والملتبسة == The Use of p16INK4a and In Situ Hybridization and Their Impact on the Healthy and Equivocal Pap Smears of the Cervix

Author name: ثناء جميل الخشالي
Supervisor name: ندى صالح امين | هدى مهدي الخطيب
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Throughout the past thirty years, the perception of cervicalcarcinoma has shifted from that of a mysteriously fatal disease, to one ofthe sexually transmitted, human papillomavirus (HPV) related infection.HPV DNA has been found in almost all cervical invasive and preinvasivecervical neoplasms.Conventional Pap smear, which was established in the early sixtiesreduced effectively the morbidity and mortality related to cervical cancer.Given the lower sensitivity of the Pap cytology test, new diagnosticparameters have been established. The histological features ofpreinvasive cervical neoplasia (CIN1, CIN2, and CIN3) are wellunderstood. However, misinterpretation of the morphological criteriacould lead to significant variability.The aim of this study is to identify women with equivocal and normalPap smear who are at risk for developing cervical cancer through the useof p16INK4a immunostaining and human papillomavirus (HPV) DNAtesting using in situ hybridization (ISH).Materials and MethodsIn order to identify human papillomavirus infection in minorcytological and histological abnormalities, biopsies collected from 60women 25 - 66 years of age with normal cervices and Pap smears (groupI), abnormal cervices and Pap smears (group II) and with cervicalcarcinoma (groupIII) referred to the Colposcopy Clinic in BaghdadTeaching Hospital - Medical City Complex, during the period from June2013 through July 2014. Cytology samples collected with ThinPrep forIVliquid base cytology (LBC), punch biopsy for histopathology formalinfixed and paraffin embedded. In situ hybridization (ISH) and p16INK4aimmunohistochemistry in addition to routine hematoxylin and eosin(H&E) stain were used to evaluate the histological specimens.ResultsThe age, age of marriage and parity of the three groups werestudied in relation to each of ISH and p16INK4a reactions. Agedistribution was highly significant among all age groups; in both ISH andp16 test results GI &GII (p=0.00), GI & GIII (p=0.00), GII &GIII(p=0.00) in both ISH and p16 test results. The age of marriage was notsignificant among the groups in both ISH and p16; GI & GII p (0.93), GI&GIII (0.12), GII &GIII (0.30). The effect of parity was insignificantamong all groups; GI & GII = (p = 0.66), GI & GIII (p = 0.82), GII &GIII (p = 0.79) in both ISH and p16 test resultsp16INK4a immunoreaction : Among group I there was a negativereaction in all the specimens collected. In specimens from group II, therewas a very mild or focal p16INK4a immunoreaction in one specimen(5%), a moderate immunoreactivity in 9 specimens (45%), and a highpositive reactivity in 10 specimens (50%) (p=0.000). Group III showedvery high immunoreaction in all the specimens collected.In situ hybridization (ISH) in group I was mild positive in 4specimens (20%) which showed diffuse signal pattern. A mild positivereaction with diffuse nuclear staining was noticed in 4 (20%) of thecervical specimens. Moderate positive reaction with diffuse staining ofthe nucleus was observed in 8 (40%) of the specimens. The remaining 8(40%) of the specimens showed both diffuse and punctate staining of theVnuclei. Among group III specimens, the nuclei in the epithelial cellsshowed both punctate and diffuse signal patterns.Chi square was done to compare results concerning ISH & variousgroups was highly significant (p= 0.00) ConclusionHPV infection is prevalent and can be missed by the conventional Pap smear. The severity of the disease was directly proportional with the age of women in this study. p16 overexpression was correlated with the positivity of ISH. This may support the use of either, or both, tests to improve the accuracy of cervical intraepithelial neoplasia (CIN) diagnosis, and help in the triage of women with equivocal lesions.

تاثير الفيتامينات B1,B6 and B12) على الاعتلال العصبي المحيطي : دراسة نسيجية، نسيجية كيميائية وكيميا نسيجية مناعية == The effect of vitamins B1, B6 and B12 on peripheral neuropathy , Histological , Histochemical and Immunohistological studies

Author name: صالح مهدي علي
Supervisor name: معن حمد الخالصي
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Peripheral neuropathy is a nerve injury process by disease or so on leading to damage of peripheral nervous system . Diabetes mellitus and compression are most common causes of peripheral neuropathy. Vitamins (B1,B6 and B12) commonly used for treatment of peripheral neuropathy. The objective of this study is to compare the effect of vitamins (B1,B6 and B12) on nerve regeneration and recovery after induced sciatic nerve crush injury in experimental animal model.Seventy five male Swiss albino rats were divided randomly into five groups and each group consisted of 15 animals. Group A( which considered as control positive(with crush injury) received normal saline intramuscularly for 45days. Group B received vitamin B1 , group C received vitamin B6 , group D received vitamin B12 and group E which considered as control negative(no crush injury and no treatment) . All animals were injected vitamins intramuscularly for 45days. Tail flick test time was reduced in rats treated with vitamin B12 after crush injury to the Sciatic nerve. Mid thigh circumference (MTC) was significantly increase in B12 treated group after crush injury to the Sciatic nerve. Data analysis was performed by SPSS 20 software using descriptive statistics.IVHistological examination of rats sciatic nerves stain by H&E on day 15 showing degenerative nerve fibers with Schwann cell infiltration in all groups but it is less prominent in group D. On day 45 histological examination of rats gastrocnemius muscles exhibited separation of bundles muscle fibers by connective tissue, variation of fibers in size and shape with atrophy of muscle bundles in all groups .While these were less prominent in rats treated with B12.Van Giesons staining of rat sciatic nerves on day 45 after crush injury. In all groups experimental and control (B,C,D,A) showing degenerative nerve fibers in different areas but less in group D and better organized sciatic nerve fibers in group D.Finally, Immunohistochemical study of (anti S100 protein) of rat sciatic nerves on day 45showed strong activity for those rats treated with vitamin B12 while rats treated with vitamin B1 and B6 exhibited moderate and weak activities respectively .In conclusion vitamin B12 promote peripheral nerve regeneration more than vitamin B1and vitamin B6.

تاثيرات عقاري المتفورمين والاناستروزول على شكل ووظيفة المبيض في بمتلازمة تكيس المبايض في الجرذان : دراسة شكلية قياسية، نسيجية، وكيميانسيجية == The Effects of Metformin and Anastrozole on the Morphology and Function of the Ovary in Polycystic Ovarian Syndrome Rat Model, Morphometrical, Histological, and Immunoistochemical Study

Author name: علي محسن عبد الامير
Supervisor name: معن حمد الخالصي
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:

دراسة تاثير اديبونكتين على هيكل كبد الفئران وعلاقته بالنظام الغذائي وكمية الدهون في الجسم == A Study Of Adiponectin Effects On The Mice Liver Architecture In Relation To Dietary Intake And Body Fat Content

Author name: غسان علي عبد الحسین
Supervisor name: سلمان شفیق سلمان | عماد غانم قاسم
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Mustansiriyah University
Language: English
University location: Baghdad
First pages:
Abstract: يعتبر مرض الكبد الدهني غير الكحولي الاضطراب المزمن الاكثر شيوعا في الكبد واصبح تشخيصه في ازدياد مع زيادة وباء السمنة العالمي وقد تم تصميم الدراسة الحالية لدراسة الفوائد المحتملة للاديبونيكتين على النماذج الحيوانية من مرض.تم تطوير نموذجين من اضطراب الكبد | Non - alcoholic fatty liver disease is the most common chronic liver disorder whose prevalence has been on the rise with the worldwide increasing pandemic of obesity. The current study was designed to study potential benefits of the adipokine (adiponectin) on animal models of non - alcoholic fatty liver disease.Two models of the disorder were developed using two different approaches. In experiment 1 (25 mice, last 8 weeks), fatty change was induced using high fructose intake to simulate human - like diet induced obesity and fatty liver disease. In experiment 2 (25 mice, last 3 weeks), fatty liver damage was induced by using methionine - choline deficient diet. Animal body weights, absolute and relative liver weight, food consumption and fructose water consumption were recorded. Visceral (epididymal) fat and liver tissue were studied using routine hematoxylin and eosin staining and histochemical stains including Masson trichrome, Periodic acid schiff and reticulin stains. Morphological and morphometric changes were compared between animals treated with adiponectin, untreated diseased animals, and control healthy animals and a non - alcoholic steatosis activity score was used to evaluate the severity of liver damage. Random blood sugar and serum lipid levels were also included as biochemical metabolic parameters.High fructose intake resulted in larger visceral fat depots and weight gain, effects that were combated by adiponectin treatment despite increased food intake. Hepatic steatosis, inflammation, pyknotic pictures and fibrosis were reduced in adiponectin treated animals resulting in a lower activity score. Random blood sugar levels were normal in all animal groups but were significantly lower in adiponectin treated groups. TG and VLDL were alleviated with adiponectin treatment.Methionine - choline deficient diet resulted in emaciation of animals, much reduced visceral fat depots but a more severe form of liver fatty damage over a shorter period of time when compared to high fructose obese animal models. Weight loss was worsened after adiponectin treatment. Hepatic steatosis, inflammatory foci, ballooning degeneration and fibrosis were all exaggerated but remained significantly less severe with less activity score in adiponectin treated animals. Random blood sugar levels were normal in all animal groups but were significantly higher after adiponectin treatment. TG and VLDL was alleviated with adiponectin treatment.Adiponectin affects appetite, food consumption and body composition in healthy animals and animal models of non - alcoholic fatty liver disease through different mechanisms. It has beneficial effects in reducing body weight in obese animals but can modulate weight loss in lean animals on methionine - choline deficient diet. Adiponectin has autocrine/paracrine effects on visceral adipose tissue and can correct the dyslipidemic picture of fatty liver disease. The antisteatotic and antifibrotic effects of adiponectin carry greater therapeutic potentials in obesity - related liver disease.

هرمون اللبتين والاستقلاب : دراسة كيميانسيجية وكيمياحيوية شاملة في الحيوانات الطبيعية والمصابة بالسكري == Leptin And The Metabolism : A Comprehensive Histochemical And Biochemical Study In Healthy And Diabetic Animals

Author name: سامح سمیر موسى عكیلة
Supervisor name: سلمان شفیق سلمان | سامیة عباس علیوي
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Mustansiriyah University
Language: English
University location: Baghdad
First pages:
Abstract: The adipocytokine leptin is a major player in the pathogenesis of diabetes mellitus and obesity. Since its discovery around 20 years ago, leptin has been; and still is; the subject of extensive research.The current study was designed to examine the effects of physiological doses of leptin on major organs involved in metabolism. The anatomical, histochemical, physiological, and biochemical effects of leptin were studied in healthy animals and in animal models of type 1 and type 2 diabetes.Eighty male albino mice were divided into three groups. The first group (A) consisted of healthy non - obese non - diabetic animals, a subgroup (A1) of which received leptin therapy to study its effects under normal conditions without metabolic disturbances. In the second group (B), a model of diet induced obesity and insulin resistance was developed using a combination of high fat diet and low dose streptozocin injection. In one subgroup (B1), the effects of leptin were studied under dietary manipulation after the discontinuation of high fat diet. In other subgroups, leptin effects were examined with continuous HFD with (B3) and without (B2) concomitant metformin therapy. The third group animals (C) represented a type 1 DM model developed by high dose streptozocin injection. A subgroup (C3) served as model control, not receiving any hormonal therapy. The others two subgroups received leptin treatment with (C2) and without (C1) concomitant insulin therapy.Statistical parameters for the study included the body weight, food and caloric consumption, adiposity index and specific organ weights and weight ratios. The epididymal fat pad, liver and pancreas were examined for gross anatomical and histological changes. Adipose tissue and some pancreatic sections were stained with H&E, liver sections were stained with periodic acid schiff stain, other pancreatic sections were stained with modified Gomori's aldehyde fuchsin. Random blood sugar and serum lipid levels and insulin tolerance test were also studied as biochemical parameters.Leptin therapy in healthy non - obese animals resulted in a reduction in food consumption, body weight, adiposity index and white fat pads weight. It also caused a reduction in the diameter and surface area of epididymal adipocytes. Serum TGL and LDL levels were significantly reduced. iiiThe same effects were seen in group B animals that underwent dieting or received metformin, but not in ones receiving leptin alone. Animal models of type 1 DM showed a moderate response to leptin therapy alone but the response was dramatically enhanced when treatment was combined with insulin. Sever weight loss and polyphagia of type 1 DM were greatly ameliorated by leptin therapy and there was an improvement in fat pad weights and adipocyte measurements. The hepatic glycogen content and insulin sensitivity were greater in animals treated with leptin (A1), on diet and leptin (B1) or metformin (B3) and in animals on leptin with insulin (C1). This was associated with significantly lower levels of random blood sugar. The pancreatic islet surface area was markedly reduced while the ? - cell/ ? - cell ratio was increased in treated animals.Leptin therapy can alter body weight and adiposity index by affecting appetite and food consumption via central and peripheral mechanisms involving the control of feeding behavior and manipulating the processes involved in carbohydrate and lipid metabolism. It can also correct the metabolic disturbances of type 2 DM but requires the concomitant use of metformin and/or the manipulation of dietary content of fat and carbohydrates. Much of its influence arises from its ability to enhance insulin sensitivity.Leptin also has a sparing effect on hepatic glycogen, favoring in turn the use of fatty acids for energy expenditure. Leptin effects on blood glucose are insulin dependent in most cases but can be insulin - independent in type 1 DM by utilizing alternative metabolic pathways for energy expenditure and interacting with hyperglycemia - inducing hormones.

Postnatal histomorphological development of the ovary, uterine tube and uterus in normal and ovariectomized local rabbits (Oryctologus cuniculus)

Author name: منى رضا علي الدهان
Supervisor name: فرحان عودة ربيع | احسان حمودي التميمي
General topic: Veterinary Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - College Of Veterinary Medicine
Language: English
University location: Baghdad
First pages:

دراسة دور فيتامين سي على الاصابة التجريبيه بتصلب الشرايين العصيدي في ذكور الجرذ

Author name: مهدي صالح شلال الهيتي
Supervisor name: سالم رشيد حمودي العبيدي | شاكرمحمود مرهش
General topic: Veterinary Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - College Of Veterinary Medicine
Language: Arabic
University location: Baghdad
First pages:

دراسة تشريحية ونسيجية وفوق عيانية للمنفحة وتطور غددها في ذكور المعز العراقي الاسود (Caprus hircus) == Anatomical, Histological And Ultrastructural Study Of Abomasum And Its Glands Development In Iraqi Male Black Goat (Caprus Hircus)

Author name: ايمان موسى خليل النعيمي
General topic: Veterinary Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - College Of Veterinary Medicine
Language: English
University location: Baghdad
First pages:

التغيرات الشكلية للمشيمات في النساء المصابات بداء المقوسات الفعال == Morphological Changes Of Placentae In Women With Active Toxoplasmosis

Author name: مها عبد الجبار السماك
Supervisor name: عبد الجبار ياسين الحبيطي | عبد الجبار
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Al Mosul - Faculty Of Medicine
Language: English
University location: Mosul
First pages:

دراسة تشريحية وطوبوغرافية للجيوب الانفـية في الانسان لفئات عمرية مـختلفة من خلال التشريح العياني والتصوير الشعاعي الطبقي == Anatomical And Topographical Study In Different Age Groups Of Human Paranasal Sinuses : By Gross Anatomy And Computerized Tomographic Imaging

Author name: محمد احمد عبد الله
Supervisor name: عبد الجبار جميل مهدي السامرائي
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Tikrit University - Faculty Of Medicine - Department Of Anatomy, Histology And Embryology
Language: English
University location: Salahaddin
First pages:

دراسة عيانية تشريحية وقياسية للقسم العصبي لجمجمة الطفل حديث الولادة == Gross Anatomical And Morphometrical Study Of Human Neonate Neurocranium

Author name: سعد احمد محمد علي
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Tikrit University - Faculty Of Medicine - Department Of Anatomy, Histology And Embryology
Language: English
University location: Salahaddin
First pages:

تغييرات العصبونات في القرن البطني وعقد الجذر الظهري للحبل الشوكي بعد قطع العصب الوركي في فئات عمرية مختلفة في الارانب == Neuronal Changes Of The Ventral Horn And Dorsal Root Ganglia Of Spinal Cord After Sciatic Nerve Section In Different Age Groups In Rabbits

Author name: بان اسماعيل صديق
Supervisor name: اياد حميد ابراهيم | عبد الكريم سالم ماهود
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Tikrit University - Faculty Of Medicine - Department Of Anatomy, Histology And Embryology
Language: English
University location: Salahaddin
First pages:

تاثير التعرض للفورملدهيد على دم وانسجة بعض الاعضاء == Effect Of Exposure To Formaldehyde On The Blood And Histology Of Some Internal Organs In The Rabbits

Author name: اياد عبد الرحمن محمد السراج
Supervisor name: عبد الجبار ياسين الحبيطي
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Al Mosul - Faculty Of Medicine
Language: English
University location: Mosul
First pages:

دراسة نسيجية لخزع الكبد الماخوذة بوساطة الناظور والطرائق التقليدية == Histology Of The Liver Biopsies Removed By Laparoscopic And Conventional Techniques

Author name: حافظ علي محمود العشو
Supervisor name: الياس اسحق شعيا
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Al Mosul - Faculty Of Medicine
Language: English
University location: Mosul
First pages:

The Effect Of Black Cumin (Nigella Sativa Linn.) And Some Other Folk Herbs On The Male Reproductive System Of Rat

Author name: فردوس م. جعفر
Supervisor name: Fara’id Y.S. Haddad | Hiwa Bakar
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:

التاثير العشبي على قلة النطاف وفقد النطاف اللانطفية : دراسة نسيجية وكيمياحياتية == Herbal Influences On Oligospermia And Azoospermia; Histological And Biochemical Studies

Author name: رياض لفتة متعب
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:

دراسة تشريحية ونسيجية لرئة الانسان قبل وبعد الولادة == Anatomical And Histological Study Of Prenatal And Postnatal Human Lung

Author name: حيدر عبد الرسول جعفر
Supervisor name: Ayad Hameed Ibraheem | Samira Abdul | Hussain Abdulla
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Tikrit University - Faculty Of Medicine - Department Of Anatomy, Histology And Embryology
Language: English
University location: Salahaddin
First pages:

تاثير بعض من مستخلصات بذور الحلبة على اجزاء من الجهاز التناسلي الانثوي للجرذان العذارى : دراسة نسجية, كيميانسجية, تاثير هرموني ومسحات مهبلية == The Effect Of Various Fenugreek Seeds Extracts On Un Coupled Female Rats Genital Tract : Histological, Histochemical, Hormonal & Cytological Approach

Author name: اسراء معتوق سليمان الجلبي
Supervisor name: Kais A.W.Al | Neamy
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:

تاثير عشب القريص على جلد ذيل الفار كنموذج مطابق لداء الصدفيه في الانسان : دراسة نسيجيه

Author name: عبد الجبار جميل مهدي
Supervisor name: غنام مصطفى الشيخ
General topic: Medicine
Specific topic: Anatomy and Histology and Embryos
Degree: Doctorate
University: Tikrit University - Faculty Of Medicine - Department Of Anatomy, Histology And Embryology
University location: Salahaddin
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