Show: 25 50 75 100 Results

Search results: 25 out of 6,846

تقييم ممارسات الامهات مع اطفالهم المصابين بمرض الناعور الوراثي المراجعات مركز امراض الدم في مستشفى بابل التعليمي للنسائية والاطفال - محافظة بابل == Assessment of Mothers' Practices Regarding their Children with Hemophilia in Blood Disease Center at Babylon Teaching Hospital for Maternity and Pediatric / Babylon Governorate

Author name: مرفت ظافر حيدر
Supervisor name: منى عبد الوهاب خليل | فخرية جبر محيبس
General topic: Medicine
Specific topic: Nursing
Degree: Master
University: University of Babylon - Faculty Of Medicine
Language: English
University location: Babylon
First pages:
Abstract: دراسة وصفية (مقطعية) اجريت في مستشفى بابل للنسائية والاطفال على الامهات الاتي لديهن اطفال مصابين بمرض الناعور الوراثي. بدات الدراسة في 24 من كانون الثاني الى 1 تموز من عام 2015. وتهدف الدراسة الى تقييم ممارسات الامهات مع اطفالهن المصابين بمرض الناعور. وتحديد العلاقة بين هذه الممارسات والخصائص الاجتماعية والديموغرافية لامهات واطفال والعينة. عينة الدراسة غير عشوائية (غرضية) مختارة من مستشفى بابل للنسائية والاطفال. اجريت على (100) ام لاطفال مصابين بالناعور الوراثي واللاتي يراجعن مركز امراض الدم في المستشفى.استبانة الدراسة تم اعتمادها وتطويرها من قبل الباحث بعد مراجعة واسعة للدراسات والمقالات المتعلقة بموضوع الدراسة, وتتكون من (5) اجزاء تشمل الخصائص الاجتماعية للامهات واطفال العينة وممارسات الامهات المتعلقة بالرعاية والتغذية والمتابعة.تم جمع البيانات من خلال المقابلة المباشرة مع امهات العينة. تم تحديد صحة وموثوقية الاستبانة من قبل مجموعة من الخبراء ومن خلال الدراسة التجريبية. وتم استخدام برنامج (SPSS) للتحليل الاحصائي, واستخدم للتحليل الوصفي (النسبة المئوية (%), المتوسط الحسابي (X) والانحراف المعياري) واستخدم للتحليل الاستنتاجي تحليل التباين (ANOVA). اظهرت نتائج الدراسة من خلال خصائص الامهات الاجتماعية ان (20%) من الامهات اعمارهن تتراوح بين(26 - 30 ) عاما, بينما الغالبية منهن (79%) ربة منزل, و(43%) هن خريجات الدراسة الابتدائية ويسكن مناطق حضرية, و(67%) من الامهات لديهن علاقة قرابة مع ازواجهن وعلاوة على ذلك اظهرت الدراسة من خلال الخصائص الديموغرافية للاطفال المصابين بمرض الناعور ان (32%) اعمارهم تتراوح بين (7 - 9) سنوات. و(41%) منهم كان تسلسلهم الثاني في اطفال العائلة ومع ذلك كانت الغالبية (70%) تم تشخيصهم بالمرض بعد 6 اشهر من الولادة ولكن (62%) يتم تلقيحهم بانتظام و(63%) من اطفال امهات العينة يذهبون الى المدرسة. واما نتائج ممارسات الامهات المتعلقة برعاية وتغدية ومتابعة الاطفال المصابين بمرض الناعور الوراثي اظهرت الدراسة ان المتوسط الحسابي للممارسات كان (1.64) والذي هو اقل من المتوسط الحسابي المرجح وهو(2) وهذه النتيجة تشير الى ضعف ممارسات الامهات في رعايتهم لاطفالهم المصابين بالناعور الوراثي. كما اظهرت الدراسة علاقة ذات دلالة احصائية بين ممارسات الامهات وبعض من الخصائص الاجتماعية المدروسة (عمر الام, التحصيل الدراسي ,بيئة منطقة السكن, علاقة القرابة بين الام والاب, والتاريخ الوراثي للعائلة) وايضا هناك علاقة ذات دلالة احصائية بين ممارسات الامهات وبعض الخصائص الاجتماعية المدروسة ( ترتيب الطفل في العائلة وانتظام التلقيح).والتوصيات المقترحة من خلال هذه الدراسة. تطوير برنامج تعليمي للابوين يتعلق بالرعاية المنزلية للاطفال المصابين بمرض الناعور الوراثي, وضع برنامج تدريب منتظم في مراكز امراض الدم للامهات الجدد اللاتي تم تشخيصهن اطفالهن حديثا بمرض الناعور الوراثي للتحسين من ممارساتهن. | A descriptive study has been conducted in Babylon Teaching Hospital for Maternity and Pediatric on mothers with hemophilic children. The study started at 24th Dec 2014 to 1st July of 2015. This study aimed to assess the practices of mothers with hemophilic children, identify the association between mother's practices with their certain demographic data, and to identify the association between mother's practices with certain demographic data of hemophilic children. A non - probability (purposive) sample selected from Babylon Teaching Hospital for Maternity and Pediatric conducted on (100) mothers with hemophilic children were visiting the Blood Disease Center in the hospital. The instrument of the study was a questionnaire which was designed and developed by the researcher after extensive literature review and the articles related to this subject which is composed of (5) parts : mother and child some certain demographic data, mother practices related to care, nutrition, visiting the clinic and follow up. The data was gathered through direct interviews with mothers. Reliability and validity of the questionnaire was determine through a pilot study and the panel of expertise. A statistical analysis was done by the use of (SPSS) the descriptive analysis, percentage (%) mean (x) standard deviation and the relative efficiency and in inferential analysis use one way (ANOVA). The study results showed that (20%) of mothers aged between (26 - 30) yrs. While, the majority of them (79%) were housewives , however, (43%) of them were primary school graduates and lived in urban areas, and (67%) of them had a relative kinship with their husbands. Moreover, the hemophilic children demographic characteristics showed that (32%) of them were (7 - 9) yrs old. The second child effected was (41%), however, the majority (70%) of them were diagnosed after the sixth month, about, (62%) of children were regularly vaccinated and (63%) of children attended school. Concerning mothers practices related to care, follow up and nutrition the arithmetic mean was (1.64) which was less than the Cutoff point (2). This indicates poor practices of mothers caring of hemophilic children. The results showed significant relationship between mothers' practices and some of their demographic data (mother's age, academic qualifications, environment of residential area, kinship between parents and genetic family history). There were significant relationships between mothers' practices and some of hemophilic children demographic data (birth order, regularly of vaccination). The suggested recommendation developed an educational program regarding home care management to parents with hemophilic children. It is important establish a regularly training program in Blood Disease Centers to new mothers with hemophilic children who were newly diagnosed to improved their practices regarding the care of their hemophilic children.

تحضير مصل تشخيصي متعدد التكافؤ لبكتيريا السالمونيلا للنمطين المصليين Typhi وTyphimurium == Preparation of Polyvalent Diagnostic Antisera for Salmonella serovares Typhi and Typhimurium

Author name: امير صادق ياسر العذاري
Supervisor name: حبيب صاحب نهر | علاء حسين حيدر
General topic: Medicine
Specific topic: Microbiology
Degree: Master
University: University of Babylon - Faculty Of Medicine
Language: English
University location: Babylon
First pages:
Abstract: اجريت هذه الدراسة على عزلتين مختلفتين لبكتريا Salmonella ( typhi وtyphimurium ) تم الحصول عليهما من مختبر الصحة العامة في محافظة النجف خلال شهر كانون الاول 2014. تضمنت الدراسة ثلاثة محاور رئيسية , المحور الاول بكتريولوجي وتضمن دراسة تشخيصية للعزلتين وفق انظمة تشخيصية متقدمة ومعتمدة وتضمن المحور الثاني الكشف عن بعض عوامل الضراوة التي تمتلكها البكتريا كقدرتها على الحركة, وانتاج انزيم البروتييز والقدرة على تكوين biofilm اما المحور الثالث فقد تضمن دراسة مناعية تم من خلالها تحضير المستضد الجسمي والمصل التشخيصي متعدد التكافؤPolyvalent antisera لكل من العزلتين.تم اختبار البكتريا من خلال اجراء الفحوصات المجهرية والكيموحياتية وتقنيات Api - 20 والVitek2 ومن خلال نتائج تلك الفحوصات ومقارنتها بالصفات النوعية للبكتريا تاكد بانه العزلتين قيد الدراسة هما Salmonella typhi , وSalmonella typhimurium . اظهرت النتائج قدرة بكتريا Salmonella جنس typhimurium على استهلاك السترات , وانتاجها لكميات كبيرة لكبريتيد الهيدروجين على وسط kliglar iron agar في حين كانت لها القدرة على تخمير العديد من السكريات واهما سكر Arabinose . في حين كانت العزلة للجنس typhi غير قادرة على استهلاك السترات وانتاجها لكميات قليلة لكبريتيد الهيدروجين بالاضافة لعدم قدرتها على تخمير سكر Arabinose .كشفت الدراسة عن امتلاك بكتريا السالمونيلا لبعض عوامل الضراوة متمثلة بانتاج الانزيم المحلل للبروتينات protease enzyme وقدرتها على تكوين biofilm الذي تعتبر احدى العوامل الرئيسة في تلوث الاغذية المحفوظة وانتشار المرض اضافة الى قدرة البكتريا على الحركة بنشاط مما يمكنها من اختراق الطبقة المخاطية المبطنة للامعاء. ومن النتائج التي توصلت اليها الدراسة قدرة البكتريا على مقاومة المضادات الحيوية النيومايسن والكلورامفينكول الذي كان في السابق يعتبر المضاد الحيوي الاول في علاج الاصابة ببكتريا السالمونيلا في حين اظهرت البكتريا حساسية كبيرة للمضادين السيبروفلوكساسين والسيفترياكسون اضافة الى حساسيتها للمضادات كوتريميكسازول والتيتراسايكلين والنالدكسك اسد ,كما اظهرت العزلتين تباين في نسبة الحساسية الكبيرة الى المتوسطة للمضادين الاموكسلين والامبسيلين حيث كانت Salmonella typhi حساسة لتلك المضادات في حين كانت Salmonella typhimurium متوسطة الحساسية لتلك المضادات .المصل التشخيصي متعدد التكافؤPolyvalent diagnostic antisera تم تحضيره خلال طريقة مقترحة من قبل جامعه فلوريدا. حيث تم تحضير المستضدات الجسمية لكلتا العزلتين لبكتريا السالمونيلا المقتولة بالحرارة وحقن هذه المستضدات في الحيوانات المختبرية ( ارانب ) التي قسمت الى ثلاثة مجاميع حقنت الاولى والثانية منها بمستضدات جسمية مختلفة للعزلتين المختلفتين وباربعة جرع بين حقنة واخرى ثلاثة الى اربعة ايام في حين حقنت المجموعة الثالثة بالمحلول الملحي الفسلجي واستخدمت كمجموعة سيطرة للمقارنة تم بعد الحقنة الرابعة للحيوانات سحب الدم من الحيوانات بطريقة ثقب القلب تم عزل المصول واختبار كفاءتها في الكشف عن البكتريا من خلال فحص التلازن agglutination test لكلا المستضدين مع الاضداد المتمثلة بالمصل وكانت النتيجة موجبة لكلا الفحصين . اما عند مزج المستضد للعزلة الاولى مع الضد العزلة الثانية فقد اظهرت نتيجة موجبة للتلازن لكنها كانت ضعيفة مقارنة مع النتيجة الاولى, في حين عند عمل تفاعل مع بعض انواع من البكتيريا الواقعة ضمن العائلة المعوية فكانت النتيجة غير جديرة بالذكر | The present study was executed on two different isolates of Salmonella (typhi and typhimuruim) which were obtained from Central Health Laboratory in AL - Najaf province during December 2014. The study included three main parts. The first part was to confirm diagnosis of those isolates based on reliable diagnostic procedures. The second part concerned with the study of some virulence factors of Salmonella such as motility, production of protease enzyme and ability to formation of biofilm. The last part included immunological study including preparation of somatic antigen and polyvalent diagnostic antisera for each isolates. The suspected isolates were fully identified by using bacteriological, biochemical, API 20E and Vitek2 techniques. The results of these tests which compared with specific characteristics of Salmonella indicated, it was that the isolates included in this study were Salmonella typhi and Salmonella typhmurium . The results revealed that ability of Salmonella genus typhimurium was able to utilize citrate, produce high amount of H2S in Kliglar iron agar and ferment Arabinose sugar, while Salmonella typhi was incapable to citrate utilization and produce little amount of H2S in Kliglar iron agar and has inability to ferment Arabinose sugar. The results revealed that Salmonella produced virulence factors represented by producing protease enzyme and biofilm formation which consider as the main factor in contaminating of food and transmission of disease. The results exhibited a remarkable resistance of Salmonella to Neomycin and Chloramphenicol which was consider the first choice in treatment of Salmonella, but it was sensitive to Ciprofloxacin, Ceftriaxone, Cotrimoxazole, Tetracycline and Naldixic acid, while it exhibited variable sensitive to Ampicillin and Amoxicillin . Polyvalent diagnostic antisera were prepared according to protocol being suggested by Florida State University. Preparation of heat killed somatic antigen for each isolates of Salmonella, then were injected in three groups of laboratory animals (rabbits). The first and second group was injected with different somatic antigen in four successive doses with an interval time of three to four days, while the third group was injected with normal saline which used as control. Blood was collected from animals by intracardiac injection then serum has been separated and tested for its specificity by reaction with Salmonella typhi and Salmonella typhimurium using the agglutination test. The results were highly positive and specific, but when test antigen of first isolate with serum of second isolate will exhibit positive result with weak agglutination, then when cross reaction prepared antisera with live antigens of other some species belong Enterobactrecea the results was no considerable reaction

نتئج تنظير القولون والفحص النسيجي لمراجعي مركز التنظير البالغين في مستشفى الحسين التعليمي 2018 == Colonoscopic and histopathological finding among adults attending to Al Hussein teaching hospital colonoscopic center 2018

Author name: وجدان عجيل حسن
Supervisor name: علي عبد سعدون الغزي | فائز خلف عبد المحسن
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine - Department Of Family And Community Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: Colonoscopy is a preventive, diagnostic & possible therapeutic safe procedure .Its results influence patient’s life and outcome. To estimate the extent of abnormal colonoscopy finding among adults attended to colonoscopy center, to estimate the extent of pathological finding among patients which were biopsies had been taken , to find out the main determinant of clinical and pathological findings of colonoscopy , and to estimate the validity of colonoscopy hospital based analytical cross sectional study carried out. It is extended from beginning of February 2018 to second week of September 2018. It was carried out in Al Hussein teaching hospital in Al Nasiriyah city Thi Qar Governorate . A convenience sample of (178) attended to colonoscopy center was included in the study. The researcher try to study the socio - demographic characters and determinant using a well prepared questioner that approved by ethical committee. It was revised by two experts in medicine. Statistical Package for Social Sciences (SPSS) version 23 was used for data analysis P value (0.05) was a cut - off point for measuring statistical association .The colonoscopy findings for178 participants were as follow the normal cases were 76 (42.7%), internal hemorrhoid in 49 cases (27.5%) , nonspecific inflammation in 23cases (12.9%) , polyp in 20 cases in (11.2%) , inflammatory bowel disease in 7cases (3.9%) , colorectal cancer in 6 cases (3.4%) , and other diseases in 7cases (3.9%) Some patients had more than one abnormality.The histopathological result of colonoscopic biopsies for 39 cases which were as follow non - specific inflammation 25 cases (64.2%) ,colorectal cancer 6 cases (15.4%) , and inflammatory bowel disease 4 cases (10.2%) , and polyps 4 cases (10.2%) .About the diseases that diagnosed by colonoscopy there was a significant statistical association between age groups and specific diseases like inflammatory bowel disease, non - specific inflammation diverticular diseases , and polyps. No significant statistical association between age and colorectal cancer .Bleeding per - rectum is a big predictor sign and symptoms of lower gastrointestinal problems , and it is the main cause of referral. The Combination of diazepam and pethidine represent the highest percent (87.6%) of intravenous sedation used in 156 cases.Adequate bowel preparation in 133 cases (74.7%) while inadequate preparation was in 34 cases (19.1%) ,and bad preparation was in 11 cases (6.2).About the site of polyp we found that the most commen site of polyp others colonic polyp 9 cases (45%) , sigmoid polyp 6 cases (30%) ,and rectal polyp 5 cases (25%). While the distribution of carcinoma according to the site of location . Carcinoma of sigmoid were 3 cases (50%) , carcinoma of other colon were 2 cases (33.3%) ,and carcinoma of rectal was 1 case (16%). Sigmoid represent the most common site of occurrence of carcinoma.Colonoscopy is 92.30 % sensitive in diagnosis lower GIT problems .The most common cause of referral was bleeding per - rectum and most abnormal finding was internal heamorrhoid . Inadequate prepared bowel hide small pathology

معدل انتشار ومحددات الامراض المهنية في مدينة الناصرية في العام 2018

Author name: صفاء خضير عباس
Supervisor name: علي عبد سعدون الغزي | مسلم ناهي الهلالي
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine - Department Of Family And Community Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: Background : Occupational diseases and work - related injuries are a significant public health problem with severe consequences for workers and society (disabilities, lost working time, medical care). It's a major epidemic problem in the field of public health in developing countries .Aims : 1. Assessment of general workers' health.2. Exploring the extent and determinants of the occupational diseases in Al - Nasiriyah province in 2018.Method and material : An analytical cross - sectional study for exploring the extent of occupational diseases which was conducted in Al Nasiriyah thermal electrical plant, cable plant and oil refinery in the Al Nasiriyah - city at 2018. A multistage cluster sampling method was conducted to recruit (369) workers. The data gathered by survey questionnaire and processed by statistical analysis.Results : The extents of the occupational diseases and occupational injuries were about 68.02% and 22.5% respectively with diseased to non - diseased ratio equal to (2.1 : 1) and injured to non - injured ratio equal to (0.29 : 1) among the workers in AL - Nasiriyah city in 2018. The highest extent (46.6%) was being within the (From 41 - 50 years) age group. The extents of the occupational diseases for the males and females were accounting for 75.3% and 31.1% respectively with the male : female ratio equal to 12.2 : 1. Binary Logistic Regression was done for adjusting the confounder factors for systematically classified occupational diseases. An odds ratio was equal to (19.1).Recommendations : Introducing the speciality of the occupational doctor in primary health care. Requesting from the medical committees in Thi Qar Governorate Council of Nasiriyah for the establishment of the (Thi - Qar Occupational Medical Centre) to promote the optimal occupational medical care.

دراسة معدل انتشار ومحددات امراض العيون في العيادة الخارجية في الناصرية خلال عام 2018 == Epidemiology Of Ophthalmological Disease in Outpatient Clinic in AL - Nasiriya During 2018

Author name: هالة علي حسين
Supervisor name: علي عبد سعدون الغزي | واجدة سعد بنيان
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine - Department Of Family And Community Medicine
Language: English
University location: Dhi Qar
Key words:
  • AL Nasiriya
  • 2018
  • epidemiology of ophthalmological disease.
First pages:
Abstract: Background : Ophthalmological disease especially (ocular allergy) represents one of the most common conditions encountered by ophthalmologists.Allergic conjunctivitis is often underdiagnosed and consequently undertreated. Basic and clinical research has provided a better understanding of the cells, mediators, and immunologic events, which occur in eye allergy.Objectives : This study was carried out to provide a profile on the epidemiology of ophthalmological disease in outpatient clinic in Al - Nasiriya at 2018.Materials and methods : Cross - sectional analytical study involved 1000 patients, attending Al - Habboby Teaching hospital _ophthalmology out patient in Al Nasiriya , the study extended from February to September 2018. sociodemographic factor ,current history of ophthalmology disease and some determinants, specific investigation had implemented from each patient to assess the frequency ,determinants ,distributions of the commonest ophthalmological disease, (SPSS) version 23 had been in used to analysis data when be p - value <0.05 considered as significant statistically.Results : Female to male ratio was (1.277). Mean age (35 - +2.0) , the highest Prevalence ophthalmological disease according prevalence rank as follow (allergy, viral conjunctivitis , cataract ,bacterial conjunctivitis and foreign body) the result was (32.1%,14.5%,9.5%,4.6%,4.1%) respectively. While lowest prevalence of ophthalmological disease was (astigmatism ,hyphema ,lazy eye, hordeolum, sebaceous cyst) the result was (0.1%,0.1%,0.1%,0.1%,0.1%)respectively. Where resident and education had significant statistical association.Conclusion : Ophthalmological disease specially allergy are becoming more common in Al - Nasiriya . Increasing levels of allergy carry significant clinical and economic implications, with more people at risk of the sight - threatening complications associated with high allergy.

نوع التركيب النسيجي في العقدة المنعزلة في الغده الدرقية في مدينه الناصرية لثلاث سنوات 2017.2016.2015 == HISTOPATHOLOGICAL CHARACTERS OF SOLITARY THYROID NODULE IN PATIENT UNDERGOING SURGERY AT 3 YEARS(2015_2017) IN AL - NASIRIYAH CITY

Author name: مروة ياسين عايد
Supervisor name: علاء جميل حسن
General topic: Medicine
Specific topic: Surgery
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: دراسه لتوثيق نسبه ان العقدة المنعزله في الغدة الدرقية ان تكون سرطانية الخلايا واحتمالية انتشارها للغدد اللمفاوية للرقبة عند وقت تشخيص العقدة لمرضى مدينه الناصرية في محافظه ذي قار خلال ثلاث سنوات السابقه(2017_2016_2015). المواد والاساليب : - دراسة مقطعية وصفية وتحليلية, الدراسة تتضمن تجميع عدد من الحالات المرضى الذين يعانون من عقدة منعزلة الغدة الدرقية وبعد اجراء عملية جراحية في صالات عمليات مستشفى الامام الحسين التعليمي لاستئصال العقدة تم اخذها لاجراء الزراعة النسيجية المختبريه,وقد تمت الدراسه في مختبرات مستشفى الامام الحسين التعليمي في مدينه الناصريه التي تبعد 360كم جنوبي بغداد العاصمة.تمت الدراسه من خلال السنه الدراسيه 2 /10/2017 باثر رجعي لسنوات السابقة(2015_2016_2017).وقد شملت الدراسه المرضى من مختلف الفئات العمرية وكلا الجنسين .اهداف الدراسة : - 1 - الكشف عن الحالات المسجلة باحتماليه العقدة المنعزله في الغدة الدرقية ان تكون سرطانية الخلايا.2 - معرفة عند وقت الاستئصال ان كانت الخلايا السرطانية منتشرة في الغدد اللمفاويه للرقبه ام لا ؟النتائج : هذه الدراسة شملت الحالات المسجلة للعقدة المنعزلة في الغده الدرقية خلال السنوات (2015_2016_2017)ضمت 162حاله وكانت النتائج اكثر الحالات سجلت في سنه2016 ,وكانت نسبه المريضات(96.9%)واغلبهم يتراوح عمرهم(18_45) بنسبه(67.9%)ومنهم اعمارهم(45_65)بنسبه(29.6%).وكانت نسبه ان تكون العقدة المنعزلة ذات خلايا حميده(57.4%) اكثر من نسبه كونها خلايا سرطانية(35.2%) اوصت الرسالة : 1_فتح مراكز تهتم بمتابعة الهرمونات بمشاركة فريق متخصص لعدة اختصاصات كالجراحة العامة والنسائية وطب المجتمع والاسرة ....................2_متابعة النظام الغذائي مع متخصصين تغذية.3_يتطلب اجراء مزيد من الدراسات مع تصميمات مختلفة ولفترات اطول نسبيا,ويفضل ان يكون نوع الدراسة بشكل يسمح لمتابعة لتحديد تاثير عوامل الخطر المربكة مثل العمر,والاجهاد,والاشعاع بدلا من العوامل المحددة وكذلك الدراسات المطلوبة حول الاستجابة للعلاج ومتابعة مضاعفات المرض | Background : The morbidity of solitary thyroid nodule to be benign or malignant affecting different age group and gender are generally not well established need to more focus about details histopathology and identified the characters of histopathology. AIM OF STUDY : To know histopathological characters of solitary thyroid nodule in patients undergoing in Nasiriya city at (2015_2016_2017).Patients and methodThis cross - sectional analytical study was carried out at the department of general surgery, Al_Hussain teaching hospital. It is retrospective study during 3 years ago(2015,2016,2017).The study include the collection samples of known cases of solitary thyroid nodule from operation room in ,Al_Hussain teaching hospital for 3 years about 162 cases and send it into histopathology in lab. In same hospital in Nasiriya city about 360 km south Baghdad the capital, and take the result of histopathology from lab. In same hospital.The study include different ages All age groups were included in this study. Classified into : • Child and adolescence less than 18 years old• Young adult(18_45) years old• Old adult (45_65) years old • Elderly (65years old and above)And both sexes (male and female).Results : A total samples collection to study are 162 of patients with STN during three years(2015_2017),The female (157) and the male( 5 ).majority of the studied population were female (96.9%), and most of them were at age of 18 - 45 years (67.9%), followed by the old adult 29.6%, while the other groups were having an equal percent of 1.25%., a studied total number were attending the Al - Hussien teaching hospital mostly coming at the 2016followed by 2017 then 2015.were most of them at the 2016 (41.1%), followed by 2017 (39%), while the 2015 were the smallest proportions of the contributors.most of the presented cases were with follicular adenoma (57.4%) followed by papillary carcinoma (35.2%) then follicular carcinoma (5.6%), while medullary Ca were the littlest proportion (1.9%). Child and elderly show no case of lymph node involvement, highest proportion were among adult cases, while the old adult show only (6,3%) L.N involvement , where M.Ca showing no L.N involvement, while(15.8%) of the papillary carcinoma show L.N involvement, regarding folicular Carcinoma only 11.1% of them showing L.N involvement.

مدى انتشار الاكتئاب لدى مراجعي عيادة الجهاز الهضمي في مدينة الناصرية 2018 == Extent of depression among gastrointestinal tract symptoms in medical outpatient clinic attendees in Al - Nasiriyah city at 2018

Author name: ابرار علي حسن
Supervisor name: احمد حسن حسین | مسلم ناھي سعید
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine - Department Of Family And Community Medicine
Language: English
University location: Dhi Qar
Key words:
  • depression
  • Gastrointestinal symptoms
  • Prevalence
  • Al - Nasiriyah 2018
First pages:
Abstract: Background : Depression is one of the most common mental health conditions in the general population as well as in clinical practice. In clinical studies, there is a strong relationship between gastrointestinal symptoms and depression and the gastrointestinal symptoms remain for longer time and are more serious than in patients without depression.Objective : To estimate extent of depression in gastrointestinal tract symptoms in medical outpatient clinic attendees.methods : The study was a cross - sectional analytical study for 154 adult population in the Al - Hussein teaching hospital in Nasiriya city ,conducted at first March 2018 and completed at end of September 2018. tools of method was questioner and for diagnosis of depression was used Diagnostic and Statistical Manual of Mental Disorders ,fourth edition (DSM - IV) criteria. refusal rate was zero and for statistic analysis was used SPSS version 22.Result : The study showed that 43.5 % of subjects with gastrointestinal symptoms suffer from depression. depression found in 40.7% of females and 47.1% of males . 50.0% of depressed patients were in two age groups of 20 - 44 years and ≥ 65 years.Most of depressed patients were suffering constipation (51.3%), change in appetite (51.3%), and change in weight(50.7%), where only change in appetite had significant association with depression, were p - value=0.001. More of depressedsubjects had GI symptoms with one month duration and ≥7 numbers of GIT symptoms. Recommendation : Raising awareness of general population about the depression and relation of that with GIT symptoms

دراسة العلاقة بين نسبة الصوديوم بالدم وتكرار الصرع الحراري في الاطفال من عمر 6 اشهر الى 7 سنوات في مدينة الناصرية 2018 == THE RELATIONSHIP BETWEEN SERUM SODIUM LEVEL AND RECURRENT FEBRILE SEIZURES IN CHILDREN BETWEEN 6 MONTHS TO 7 YEARS AL - NASSIRIYA CITY 2018

Author name: فلاح حسن مالك
Supervisor name: امين تركي | مسلم ناهي
General topic: Medicine
Specific topic: Family Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
Key words:
  • Febrile seizure
  • serum sodium (hyponatremia)
First pages:
Abstract: Background : Febrile seizure is the most common convulsive event in children younger than 60 months, it is often recurring within the first twenty - four hours. A febrile seizure is terrifying event for parent. Different factors enhance the occurrence of seizure and one of these factors is hyponatremia which thought to be low in children with recurrent febrile convulsion. Objective : To estimate the relation and the effect of serum sodium in recurrence of febrile convulsion. Patients and method : An observational case control study conducted on (180) child between the age of 6 months and 7 years ,all patients divided in to 3 groups ;group (A) which include (60) children presented with fever without convulsion which considered control group , group B which include (60) child presented with single febrile convulsion and last group was group C which include (60) child presented with recurrent febrile convulsion .Serum sodium was estimated for all children immediately after admission to emergency . Our study carried out in Mohammed Al Mousawi pediatrics hospital in AL - Nasiriya city during the period between May to September of 2018. Result : In our current study 180 children were included with age range between (6 months to 7 years) old. Serum sodium was estimated and we compare the result between the 3 groups of study. The study involved 89 males and 91 females. The mean serum sodium in group A, B, C, were 139.45,137.09,131.95 respectively with (p value <0.001) which found to be significant value. We estimate that decrease serum sodium levels in relation with increase recurrence of febrile convulsion, also we found that hyponatremia children are 4 times more likely to develop recurrent convulsion than children with normal or elevated serum sodium. Regarding the serum calcium, random blood sugar and Tamp., there is no significant association, but family history was significantly associated with occurrence of febrile seizure. Conclusion : The current study shows significant correlation between decrease serum sodium and recurrence of febrile convulsion us serum level found to be lower in children with recurrent febrile convulsion

تقييم ضعف السمع بين اطفال المدارس الابتدائية في مدينة الناصرية خلال عام 8102 == Hearing impairment among primary school children in Al - Nasiriya city during 2018

Author name: علي عبد سعدوى الغزي
Supervisor name: مشتاق نعمة المالكي
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: More than five percent of people in the world have disabling hearing loss . Children are thirty four millions from total four hundred sixty six million people with hearing loss . Hearing impairment among primary school children if remains unaddressed can significantly affect the academic performance of children and can result in poor psycho - social and intellectual development in children.so early detection and early intervention of hearing impairment in early childhood will ensure well - mental , social, communicational and educational development of children.Study objective : To estimate extent of hearing impairment among children of primary schools in Al - Nasiriya city and identify certain determinants .Methodology : Across - sectional and comparative school - based study was carried out through multistage systematic random sampling for 9 public primary schools in Al - Nasiriya city from1st of February/2018 - 3th of May /2018. Primary information was obtained through prepared questionnaires including the socio - demographic characters of studied pupils ,thorough otological history ; and clinical examination ( through direct observation ; and use of tuning fork test were conducted on all participants and screening audiometry was conducted for children with suspected hearing impairment). Then children with suspected hearing impairment were referred for AL - Habboby hospital to confirm the diagnosis of hearing loss by diagnostic audiometry and tympanometry and to know whether it was CHL or SNHL . The statistical analysis was done by using SPSS version 23 and tests of significance were used( x2 test and Fisher exact test ) , and the significant Probability value ≤ 0.05.Results : A total of 355 pupils were screened, 228(64.2%) of them were males and 127(35.8%) were female that ratio of male to female was 1.8 : 1. Nearly half of pupils were within 6 - 7 years at (55.2%) ,and least one were within age group >10 years (15.2%). Majority of pupils were within high socio - economic status (87.6%) , and the remaining were within moderateXIV(8.2%) - low class (4.2%). The extent of hearing impairment among pupils in Nasiriya city was 16% .Unilateral (9.2%) was more prevalent than bilateral (7%). of 58 pupils with HI , 24(41.4%), 23(39.7%) , 5(8.6%) , 4(6.9%) ,and 2(3.4%) had ear wax, otitis media with effusion , CSOM, ear wax ,and foreign body in external ear canal respectively.Of 58 pupils with hearing impairment,52(14.7%) of studied pupils had mild hearing impairment, and 6(1.7%) had moderate hearing impairment. Non showed moderately severe or sever or profound hearing loss.There was significant association between age , socio - economic status of studied population and Prevalence of hearing impairment by logistic regression analysis.Conclusion : The most affected pupils in our study were female gender , pupils aged > 10 years ,and with low socioeconomic status. Where univariate analysis shown statistical association of hearing impairment with sex , socioeconomic status, family size, ear discharge and otalgia. There was high prevalence of hearing impairment in comparable with other study. The study shown that most common ear diseases associated with hearing impairment were ear wax impaction and otitis media with effusion and the commonest degree

تقييم الخطوره على الحوامل اللاتي تراجع رعاية الحامل في المراكز الصحيه في مدينة الناصريه للعام 2018\1440 == Risk assessment among pregnant women attending antenatal care in the primary health care centers in Al - Nasiriya city in 2018 / 1440

Author name: زينب حيدر عبد الجبار
Supervisor name: الاء حسين علي الناصر | مسلم ناهي سعيد محاضر
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
Key words:
  • prevalence
  • pregnant women
  • antenatal care
  • Modified Coopland score
  • cross sectional study
  • laboratory results
First pages:
Abstract: دراسه مقطعيه وصفيه وبائيه تدرس ٥٨٦ من الحوامل في محافظة ذي قار في مركز الناصريه على المراكز الصحيه ، امتدت الدراسه من الاسبوع الثالث لشهر كانون الثاني ٢٠١٨ حتى نهاية شهر اب ٢٠١٨ ، لدراسة تقييميه للحوامل اللاتي تراجع المراكز الصحيه لاخذ رعاية الحوامل وخدمات للحوامل ودراسة تاثير عوامل الخطوره على الحامل وما هو العامل الاكثر انتشارا بين الحوامل وكم نسبة باقي عوامل الخطوره على الحوامل وعلاقة هذه العوامل على الحاله الاجتماعيه كالعمر والمهنه ودرجة التعليم والحاله الماديه ، كانت الدراسه على ٩ مراكز صحيه من مراكز المدينه : ٦ مراكز صحيه من القطاع الثاني و٣ مراكز صحيه من القطاع الاول حيث اختيرت عشوائيا ، واخذت جميع الحوامل المراجعات التي تنتمي لذلك المركز بالاعتماد على الرقعه الجغرافيه يوميا ولمدة تقريبا ٣ اشهر ونص في تجميع العينه يوميا من السبت للخميس من الساعه ٨ ونصف صباحا حتى الساعه ١ ظهرا عدا ايام الجمعه والعطل الرسميه ، وكانت نتيجة الدراسه كالتالي : منخفضة الخطوره ٦٠,٦% ، عالية الخطوره ٢٠,٦% ، جدا عالية الخطوره ١٨,٨% واما بالنسبه اكثر عامل خطوره هو التهاب المسالك البوليه بنسبة ٢٨,٩% ويليه فقر الدم بنسبة ٢٧,٨% واكثر فتره وجدت فيها عوامل الخطوره مرتفعه هي الفتره الثانيه من الحمل من الشهر الرابع حتى نهاية الشهر السادس ، وهناك علاقه مع الحاله الاجتماعيه لهذا كانت ضمن التوصيات للدراسه زيادة ثقافة وعي الحامل قبل الحمل وخلال الحمل | Background : Antenatal care services is particularly definitive for enhancing effectiveness of services for childbirth and introduce best pregnant women’s needs of antenatal care services and consequentially improve the outcome of both mothers and infants.Objectives : To assess of antenatal care in pregnant women's to identify the level of antenatal care, prevalence of risk factor according to the score among pregnant women attendens primary health care centers for antenatal care.Subjects and methods : A descriptive cross sectional study started from 15th of January 2018 to the end of august 2018 on 586 pregnant women attending nine Primary Health Care centers for antenatal care in Al Nasyria city. These nine PHCCs were located in two health Sectors, data collection continued for three months and a half.The questionnaire was prepared after a through literature review to include all potential risk factors in addition to possible related demographic and other related factors (educational level, socioeconomic level and occupation).Antenatal risks were calculated according to modified Coopland score.The data were analyzed by using the Statistical Package for Social Sciences version 23 (SPSS - 23).Result : according to Coopland score the distribution of the sample showed that : - Low risk : 355 women (60.6%) of the sample - High risk : 121 women (20.6%) of the sample - Extremely high risk : 110 women (18.8%) of the sampleThe high risk and extremely high risk cases occurred mostly in 2nd trimester. Urinary tract infection represented the prvelant risk factor (28.9%).Conclusion : the prevalence of risky pregnancy was high. Although low risk factors were found in about two thirds of the sample, high and very high risky pregnancy was found in two fifths of the sample. These findings indicated the urgent need for more facilities to improve antenatal services in the primary health care centers and to encourage women to utilize these services. Special emphasis need to be centered on high and extremely high risk groups through providing specialized care during antenatal care and put a plan for them to decrease both complication and death on both fetus and mother sides. Recommendation : the study results mandate more facilities like ultrasound to obtain more information that encourage pregnant women to visit primary health care centers and put plan for high risk pregnancy for specialized care

تقدير مدى انتشار ومحددات سرطان الثدي بين الاناث ذوات عقدة الثدي ومتغيراته الزمنية لستة سنوات في محافظة ذي قار == Extent and determinants of breast cancer among females with breast mass during 2018 in Thi - Qar province

Author name: استبرق امين حبيب
Supervisor name: علاء جميل حسن | حميد نعيم موسى
General topic: Medicine
Specific topic: Community Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: خلفية الدراسة : من اهم الاعراض الاكثر شيوعا لسرطان الثدي هي الاحساس بعقدة او كتلة جديدة في الثدي، وتعتبرايضا واحدة من اهم مؤشرات اضطرابات الثدي ، على الرغم من ان معظم عقد الثدي حميدة ، ولكن سرطان الثدي هو اكثر انواع السرطانات شيوعا في الاناث في جميع انحاء العالم ومن الاسباب الاكثر شيوعا للوفاة بسبب السرطان بين الاناث في البلدان المتقدمة والنامية بما في ذلك العراق.الاهداف : تهدف الرسالة الى تقدير نسبة سرطان الثدي الى عقدة الثدي بين الاناث التي تعاني من عقدة الثدي في ذي قار خلال عام 2018 ، ودراسة الخصائص الاجتماعية للمصابين كمحددا لسرطان الثدي مع دراسة خواص سرطان الثدي الخلوية والنسيجية في ذي قار 2018.طرق العمل : • التصميم : تم استخدام تصميم تحليلي مقطعي.• المرضى : ادرجت كل النساء اللاتي تعرضن بكتلة الثدي في عمر محدد.• اخذ العينات : تم اخذ حجم عينة طبقا لفترة الدراسة.• الاجراء التشخيصي : تم التشخيص بشكل اساسي على اساس التقييم الثلاثي(Triple test).النتائج : يشكل سرطان الثدي في ذي قار ربع الحالات المصابة بكتلة الثدي بين النساء, مع نسبة الكتلة الخبيثة للكتل الحميدة حوالي (1 : 2,8) ، ويشكل سرطان القنوات المتسلل غير المحدد النوع الشكل الاكثر شيوعا. (59.5٪) من الخلايا السرطانية كانت معتدلة التمايز اثناء الدراسة و( 32 ٪) كانت غير متمايزة اما (8.5 ٪) فان الخلايا متمايزة بشكل جيد. ، من ناحية اخرى فان معظم المرضى اكتشفوا في مراحل متاخرة (II, III, IV stages)، في حين ان 10 ٪ فقط في مرحلة مبكرة.التوصيات : 2. الفحص الدوري المبرمج اللازم للكشف عن السرطان في المرحلة المبكرة ، وتسهيل توافر ادوات الفحص في مراكز الرعاية الصحية وفي مستشفيات اقضية محافظة ذي قار.2. تعتبر عيادة الثدي جزءا مهما من الرعاية في مستشفى الحسين التعليمي وفي المحافظة ، مما يزيد من الحاجة الى مركز متخصص قادر على تحقيق الهدف الوقائي والصحي المطلوب.3. على الرغم من معظم عوامل خطر الاصابة بالسرطان ليست قابلة للتعديل ، فان عددا من العوامل يمكن التحكم بها وذلك بتغيير نمط الحياة العام بالتخلص من العادات غير الصحية كالتدخين ، وارتفاع الوزن بعد انقطاع الطمث ، وعدم ممارسة الرياضة او قلة النشاط البدني التدخين وتشجيع الرضاعة الطبيعية للحد من سرطان الثدي.4. الحاجة الى تفعيل برنامج الفحص على مستوى الرعاية الصحية الاولية مع وجود طبيب اشعة متخصص في فحص امراض الثدي في ذي قار.5. الطلب على التخصصات الفرعية الجراحية والاشعاعية في امراض الثدي ولزيادة اعداد اخصائيي امراض الانسجة لتحسين النظام الصحي.6. الحاجة لاجراء مزيد من الدراسات مع تصميمات مختلفة ولمدة اطول ، ويفضل ان يكون نوع الدراسة يسمح بمتابعة المرضى لفترات طويلة, لتحديد تاثير عوامل الخطر التي تداخل الدراسات المقطعية مثل العمر ، والاجهاد والاشعاع ، وكذلك دراسات اخرى حول الاستجابة للعلاج | Background : The most common symptom of breast cancer is a new mass. It is regarded as one of the most important indicators of breast disorders, Although most masses were benign, but breast cancer is the most common cancer in females worldwide and the commonest factor of cancer related death among females in developed and developing countries including Iraq. Aim of the study : To measure extent of breast cancer among female with breast mass in Thi - Qar, to define the most common types of malignant and benign breast mass and to study the soscio - demographic characteristics, and most important determinant of breast cancer patients counseling breast disease centre in Thi - Qar 2018.Methodology :  Design : A cross sectional analytical design was used.  Duration of study : 8 months. Patients : All women presented with breast mass at defined age, were included.  Sampling : A convenience sample size was taken. diagnostic procedure : Diagnosis was mainly done based on triple assessment. SPSS analysis has been used.Results : • Breast cancer in Thi - Qar constitute 26% of attendant with breast mass. The ratio of malignant for benign masses was 1 : 2.8.• Invasive carcinoma of NST the most common variant, and more than half of the malignant masses were moderately differentiated, one third of them were poorly differentiated, and only less than ten percent was well differentiated at the time of study. Also the majority of patients presents at late stages (II,III and 4) while only 10% at early stages (I) at the time of diagnosis.Recommendation : • Regular programmed screening required to detect the cancer in the earlier stage, and facilitate the availability of screening tools at the health care centers and in peripheries hospitals of Thi - Qar.• The breast clinic is an important part of care in Al - Hussein Teaching hospital, as its unique clinic in the governorate, so increasing the need to be specialized center.

النتائج السريرية لانثقاب المرارة اثناء عملية استئصال المرارة بالمنظار في مستشفى الحسين التعليمي 2018 == Clinical outcomes of Gall bladder perforation during laparoscopic cholecystectomy in AL - Husain Teaching hospital 2018

Author name: كاظم جواد كاظم
Supervisor name: مهند عبد الرضا عكموش
General topic: Medicine
Specific topic: Surgery
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: The most common surgical procedure as laparoscopy, performed all over the world is Lap. chole. .It has now become the golden procedure of management for gallstones. Even though, there are many attempts to explore the influence of perforation of gallbladder on the clinical outcomes, but the conflicting results are still. Because of increasing in the attempts at minimally invasive surgery, during lap chole; accidental gallbladder perforation is on rise. Aims : The researcher try to investigate criteria and the clinical outcomes and the risk factors in patients who develop gallbladder perforation during Lap Chole. Methods : An (80) patients had been undergo Lap.chole.. by a cross sectional comparative analytical study in prospective pattern had been carried out in Al - Hussain teaching hospital - Thi - Qar - Iraq. The data collection phase extended over a period of 7 months from 2nd of January 2018 to 1st of august 2018. Each participants subjected to a questionnaire that include : personal socio - demography, and fallowed up for at least one week to assess the outcome. The data analyzed by using SPSS (version 23). p value less than 0.05 was considered as statistically significant .XIIResults : Eighty (80) patients sustained a gallbladder perforation, the bulk of the sampled cases taken was females were mostly at age of 40 - 60 years, and Al - Nasiriya residency, and these are not the total number of cases of accidental gallbladder perforation during laparoscopic cholecystectomy within 7 months of the study, only two cases ended with sub - hepatic collection, there was statistical association between type of perforation and some determinants such age and gender (p value=0.001), while there was no sig. Statistical association between complication and studied variables (P value >0.05) . Conclusion : The most age of occurrence of the complication is the peak age of gall stone development, and because the large number of female patient in our study, so female consider the main affected gender for both gall bladder diseases and perforation during lap. chole.. Accidental gallbladder perforation can be caused mainly by technical errors.

نمط الامراض الجلديه للمرضى الوافدين الى العياده الخارجية للامراض الجلدية في مستشفى الامام الحسيني التعليمي في مدينة الناصرية لعام 2018 == Pattern of dermatological diseases among a sample of patients attending the dermatology outpatient clinic in Al - Hussein teaching hospital in Al - Nasiriya city 2018

Author name: زهراء جبر ابراهيم
Supervisor name: Ali A.Saadoon Al - Ghuzi
General topic: Medicine
Specific topic: Family Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: Background : skin diseases are a common problem wide world affecting both sexes and all age groups, there are many factors contributing to skin diseases such as contact with infectious patient, contact with allergen or others irritant materials, overcrowding and poor hygiene.Objective : to study the epidemiology of common dermatological diseases in Al - Nasiriya city at 2018.Methods and materials : case series study from first of February 2018 to the September 2018.try to study sociodemographic, determinant, specific laboratory investigation of common dermatological diseases under a well prepared questionnaire. The analysis of data was done by - SPSS version 25 Result : total of 1048 patients had been studied where the extent of eczema/dermatitis 38.3%, viral infection20.4%, and protozoal infection 14%.regarding to the sociodemographic the age had significant association in multivariate analysis and other determinant the past medical history had a significant association.Conclusion : eczema /dermatitis, viral infection, protozoal infection had most extent of dermatological diseases.Recommendation : further studies are required to identify preventive measures and establishment of dermatological center

دراسة الدهون الاسفنجية النشطة بايولوجيا والانزيمات الاستقلابية في كل من تضخم البروستات الحميد وسرطان البروستات الخبيث == Bioactive Sphingolipids and metabolizing enzymes in patients with benign prostate hyperplasia and malignant prostate cancer

Author name: رغدة عبد المنعم رزوقي
Supervisor name: رائد جاسم محمد التميمي | اسامة سليمان قدوري الناصري
General topic: Medicine
Specific topic: Medical Biochemistry
Degree: Master
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Bioactive Sphingolipids an important molecules of structural and signaling lipids. In this study was highlight on new biomarkers uses to investigate prostate cancer by using new method HPLC fluorescence detector to measure concentration and activity enzymes sphingosine - 1 - phosphate lyase enzyme (SPL) and Acid Ceramidase enzyme (AC) by used new material (BODIPY) aromatic structural is binding with enzymes and give fluorophore product sensitive by HPLC fluorescence detector in patients have BPH and PC in serum and tissue and comparing with healthy men as (control). Eliza method was used to measured sphingosine - 1 - phosphate and Ceramide in patients (BPH and PC) in serum and tissue with controls in serum. Sphingolipids metabolites pathological processes, are established regulators of myriad cellular and sphingolipids research is intricate due to the role of these molecules in vastly different biologics, interconnected metabolic pathways and structural properties. Ceramide and sphingosine - 1 - phosphate (S1P), SGPL and AC have been defined as reciprocal regulators of cellular fate, and not surprisingly have been targeted for their role in cancer and their therapeutic potential, sphingolipid metabolic enzymes and lipids are metabolically interconnected and highlight recent findings to support the reciprocal role of Ceramide and S1P in cellular processes and in cancer. Studies show increase levels markers in serum and tissue in BPH and PC with healthy men and different Km and V max in AC and SPL between healthy, BPH and PC patients also this reaction was noncompetitive inhibition with enzyme because V max was change and Km was not change in all cases these results were accepted with studies in America and Spain (Liu, Y.Y.; Patwardhan, G.A.;et al. 2011).IXAim of study1 - 1 - The main aim of this study is found a new sensitive and specific bio markers for diagnosis prostatic cancer And other goals of conducting this study are : 2 - To measure activity of Acid ceramidase and Sphingosine - 1 - Phospate Lyase in sera and prostate tissue of patients with benign prostatic hyperplasia and prostate cancer and compare these activities of enzymes with normal controls.3 - To determine the concentration of bioactive Sphingolipids Ceramide and Sphingosine - 1 - phosphate in tissues and sera of the patients and control.4 - To correlate the level of bioactive lipids with serum PSA concentration to detect their use as additional biomarker for diagnosis and follow up of patient with prostate cancer.Methods : A case - control study design was employed in this study. On a total of 30 patients with confirmed PC, 30 patients with BPH and age matched 30 healthy men. Prostate tissue samples were obtained for patients were serum and urine samples were collected for patients and controls. Enzyme linked immune assay (Elisa) was used to measure S1P and Ceramide concentration in serum and tissue, while HPLC fluorescence detector was used to estimate activities of SPL and AC and measured Km and V max. Urine and serum samples were undergone biochemistry analysis. HbA1c was used to measure cumulative sugar for three groups. Protein in tissue was measure by brad ford method to PC and BPH patients.Results : The results showed that increase levels of Sphingosine 1 phosphate lyase and Acid ceramidase in serum and tissue in BPH and Malignant cancer in men these levels were different result in patient wereXtaken drugs or not and patients were taken chemotherapy or not and activity, Km and Vmax of enzyme SPL and AC were different in BPH and PC that men is inhibition enzymes was noncompetitive it had same Km but different data of control, BPH and PC men in tissue and serum.The concentration of S1P and Ceramide were different levels with control, and high levels in patients without any drugs or chemotherapy while levels of these markers still low with patients were taken drugs or chemotherapy and level of protein in tissue were raised. Results of biochemistry analysis still normal because we take patients without any D.M., renal failure, and hypertension.

تقييم الانزيمات المعدنية المحللة للبروتين - 9 MMP - 9 والانترلوكين - 18 (IL - 18) في دم الحبل السري والنسج البيني في الولادات القيصرية والمهبلية الطبيعية == Matrix Metalloproteinase - 9 and IL - 18 Level in Cord Blood and Tissue Matrix in Caesarean and Normal Vaginal Delivery

Author name: خوله عبد الحمزة شمران مشجل
Supervisor name: ريا سليمان صلاح الدين بابان | مي فاضل ماجد الحبيب
General topic: Medicine
Specific topic: Clinical Biochemistry
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: ماتركس ميتالوبروتياز Matrix metalloproteinases اختصارا (MMPs) وهي انزيمات تعتمد على الزنك وتحتوي على اندوبيبتيداز endopeptidases . هذه الانزيمات لها القدرة على احداث التحلل في جميع انواع البروتينات للمصفوفة خارج الخلية، ولكن ايضا يمكن معالجة عدد من الجزيئات النشطة بيولوجيا. ومن المعروفة انها تقوم بالمشاركة في انشقاق والانقسام لمستقبلات سطح الخلية، واطلاق المعقدات المسؤولة عن موت الخلية (مثل معقد FAS)، وعدم تفعيل السيتوكينات cytokines. وايضا خلال فترة الحمل تحدث تغيرات فسيولوجية خاصة مثل نضج عنق الرحم، وتمزق الاغشية الجنينية، وانفصال المشيمة والذي تتطلب اعادة تشكيل المصفوفة خارج الخلية (ECM) . السيتوكين مثل الانترلوكين (IL - 18)يلعب دورا حاسما في دفاع المضيف، وانها قد تكون جزء في توفير حاجز لعنق الرحم/ ساقطي ضد الغزو الميكروبي من السائل الذي يحيط بالجنين وقد يكون بمثابة علامة لعنق الرحم للعدوى داخل الامنيوتك Amniotic. الاجهاد التاكسدي، وهي حاله تتميز بعدم التوازن بين الجزيئات المؤكسدة، بما في ذلك الانواع الاكسجين التفاعلية (ROS)، وبين دفاع المضادات للاكسدة Antioxidant . هذه ROS قد يسبب اصابات الانسجة مما يؤدي الى تلف البروتينات الخلوية داخل الخلايا ، والحمض النووي DNA التي تورطت في مضاعفات الحمل في بوقت مبكر اثناء المخاض، ويمكن ان يؤثر على طريقة الولادة . استجابة الجسم المناعية تتضمن المضادات للاكسدة الانزيمية وغير الانزيمية التي تقلل من تاثير هذه الجذور الحرة. تهدف هذه الدراسة الى تقييم العلاقة بين مستويات انزيم ماتركس ميتالوبروتياز - 9 (MMP - 9 )ووضعية الحمل. الطرق : في هذه الدراسة تم تعيين ستة واربعين النساء الحوامل (31 حاملا خضعن للولادة الطبيعية، 33 حاملا خضعن للولادة القيصرية. . تم جمع نموذج الدراسة من صالات النسائية والتوليد في مدينة الامامين الكاظمين الطبية خلال فترة من حزيران من 2015 الى تموز من 2016.واخذت موافقة النساء الحوامل قبل الدخول لصالة العمليات, وتم اخذ عينات من الدم وقطعة من النسيج جمعت خلال خمس دقائق من الحبل السري. تم جمع عينات الانسجة الحبل السري ايضا اثناء الولادة. واستخدمت عينات دم وانسجة لقياس الفلزي المصفوفة (MMP - 9)، وانترلوكين 18 (IL - 18)، وايضا تم استخدام نماذج الدم لقياس معدل جهد التاكسد في مصل الدم والمضادات للاكسدة (SOD) والعناصر النزرة. النتائج : اظهرت النتائج ان تدهور في المستويات الحيوية ل( MMP - 9و IL - 18) في الدم النساء اللواتي خضعن الولادة الطبيعية. وكانت عالية في النساء اللواتي خضعن للعملية القيصرية وبالاضافة الى ذلك، فان مستويات الانزيمات المضادة للاكسدة الاقل بين النساء اللواتي خضعن للولادة الطبيعية واعلى بين النساء اللواتي خضعن للعمليات القيصرية. وذكرت في الدراسة ايضا انخفاض كبير في مستوى العناصر النزرة المؤشرات الحيوية (الزنك والنحاس والمغنيسيوم) في الدم النساء اللواتي خضعن للعملية القيصرية مقارنة مع مجموعة النساء اللواتي خضعن الولادة الطبيعية. الفحص النسيجي للنسيج الحبل السري من النساء الحوامل كشفه عن نتائج مطابقة لنتائج فحوصات الدم حيث بينت عن ارتفاع معنوي في تركيز انزيم MMP - 9 والانترلوكين IL - 18 في النساء اللواتي خضعن للعملية القيصرية مقارنة مع مجموعة النساء اللواتي خضعن الولادة الطبيعية.الاستنتاجات : ارتبط الولادة الطبيعية مع زيادة الاكسدة وانخفاض في النشاط المضادة للاكسدة وفي المقابل انخفاض الاجهاد التاكسدي وزيادة في النشاط الانزيمي المضادة للاكسدة (SOD) في الولادات القيصرية ،. واضاف لذلك ارتبط الولادة الطبيعية بانخفاض معنوي في مستويات انزيم MMP - 9 والسايتوكينات IL - 18 مقارنة مع مجموعة النساء اللواتي خضعن الولادة الطبيعية. ومن ناحه اخرى اظهر الفحص النسيجي هنالك تركيزات عالية MMP - 9 وIL - 18 في الانسجة الحبل السري للمراة التي تخضع للعملية القيصرية بالمقارنة مع النساء اللواتي الولادة الطبيعية. | Matrix metalloproteinases (MMPs) are calcium - dependent zinc - containing endopeptidases. These enzymes are capable of degrading all kinds of extracellular matrix proteins, but also can process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands (such as the FAS ligand), and cytokine inactivation. During pregnancy, specific physiological changes such as cervical ripening, rupture of the fetal membranes, and placental detachment require the remodeling of the extracellular matrix (ECM). Cytokine like Interleukin - 18(IL - 18) play a critical role in host defense, and it may participate in providing a cervical/decidual barrier against microbial invasion of the amniotic fluid and might serve as a cervical marker for intra - amniotic infection. Oxidative Stress, a state characterized by an imbalance between pro - oxidant molecules, including reactive oxygen species (ROS), with antioxidant defense. These ROS may cause tissue injury resulting in cytotoxic damage to cellular proteins, and DNA which has been implicated in early pregnancy complications and during ,labor and may effect on mode of labor. Body defense response involves enzymatic and non - enzymatic antioxidant buffering pathways which reduce the effect of these free radicals. This study aimed to assess the relationship between matrix metalloproteinase enzyme levels and delivery mode and also an attempt to assess the impact of oxidative stress on maternal antioxidant defense during labour and correlate it with mode of parturition. Methods : A case - control study design was employed in this study. Sixty four pregnant women were recruited 31 term pregnant women with normal vaginal delivery and 33 term pregnant women underwent cesarean section delivery. At the time of their admission to operation theatre, blood samples were taken and a piece of tissue was collected from umbilical cord after delivery . Blood and tissue samples were used to measure matrix metalloproteinase (MMP - 9), Interleukin - 18 (IL - 18), Superoxide Dismutase (SOD) activity and trace elements levels was determined in the umbilical cord blood only. Placental tissue was prepared and stained for histological assessment. Anti - MMP - 9 and Anti - IL - 18 monoclonal antibody laboratory kits were employed to demonstrate degradation and cytokine levels in umbilical cord tissue. Results : results showed that both blood MMP - 9 and IL - 18 levels were significantly higher in term women who underwent cesarean section compared with those women who underwent normal vaginal delivery. In addition, the enzymatic anti - oxidant SOD was significantly lowest among term women who underwent normal vaginal delivery when compared term women who underwent cesarean section. The present study also reported a significant decreases in level of trace elements (Zn, Cu and Mg) in blood of term women who underwent NVD compared those a with C/S labor (P<0.01). The histological examination of umbilical cord tissue revealed that term women underwent normal vaginal delivery group had the lowest reactivity with both anti - MMP - 9 and anti - IL - 18 monoclonal antibody in comparison to term women underwent cesarean section group. From the study it was concluded that term pregnancy women underwent normal vaginal delivery was associated with increased oxidative stress and decreased anti - oxidant activity. In contrast, term pregnancy underwent cesarean section was associated with low oxidative stress status and high enzymatic anti - oxidant activity (SOD). In other hand, pregnancy underwent with cesarean section was significantly associated with high levels of serum MMP - 9 and IL - 18 and high level of enzymatic anti - oxidant activity (SOD). While the Histological examination showed high MMP - 9 and IL - 18 concentrations in the umbilical cord tissue of term women underwent cesarean section in comparison to term women underwent normal vaginal delivery

دراسة كيميائية حياتية لارتباط المستضد بضاده الحيوي في مرضى داء CA19 - الكاربوهيدراتي 9 السكري من النوع الثاني باستخدام مقايسة الممتز المناعي المرتبط بالانزيم مع بعض التحويرات == Biochemical Studies of the Binding of CA 19 - 9 to its Antibody in Patients with type 2 Diabetes Mellitus using Enzyme - Linked Immunosorbent Assay with some Modifications

Author name: رسل رياض عباس
Supervisor name: حسن حسين طه السعيد | محمود شاكر خضير
General topic: Medicine
Specific topic: Medical Biochemistry
Degree: Master
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Carbohydrate Antigen CA19 - 9 has been widely utilized for diagnosis of different kinds of cancer such as pancreatic cancer, cancer of upper gastrointestinal tract. It may also be used as an indicator of pancreatic tissue damage that may be caused by diabetes.The method of enzyme linked immunosorbent assay (ELISA) for measurement CA19 - 9 in sera of patients with type 2 diabetes mellitus was developed using external CA19 - 9 antibody (competitive sandwich ELISA technique) and found to be suitable for the determination of a dissociation constant (Kd) of the binding of CA19 - 9 to its antibody in type 2 diabetic patients using scatchard plot. Objectives : - This study was performed to assess CA19 - 9 levels in sera of patients with type 2 diabetes mellitus with non - cancerous tissue by enzyme - linked immunosorbent assays (ELISA) and define the normal range (cutoff value) for the same marker in this patients also investigated the possible relationships of CA19 - 9 with fasting plasma glucose and HbA1c.This study present a new method for determination the dissociation constant (Kd) of the binding of CA19 - 9 to its antibody in type 2 diabetic patients using scatchard plot through development of ELISA (competitive sandwich ELISA technique).Different factors affecting this binding were extensively studied such as divalent cations, different halides, and Polyethylene (PEG - 6000).

قيمة التتبع النقطي المقطع بالموجات فوق الصوتية لعضلة القلب للكشف عن مرض الشرايين التاجية مقابل تصوير الاوعية التاجية == Detection Of Coronary Artery Disease Using 2D - Regional (Segmental) Longitudinal strain (RLS) Comparing with Coronary Angiography in Patient with Acute Coronary Syndrome

Author name: عماد محمود حسين
Supervisor name: نزار ناصر عباس العتابي
General topic: Medicine
Specific topic: Echocardiography
Degree: Higher Diploma
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Background : Speckle - tracking echocardiography is a new noninvasive ultrasound imaging technique that allows for evaluation of global and regional myocardial function.Aim of the Study : to evaluate the accuracy of regional(segmental) longitudinal strain by 2D - STE for pick up culprit vessels in ACS by detecting ischemic segments of the corresponding territories and its severity compared with coronary angiography as a gold standard, in patients with acute coronary syndrome .Patients and Methods : A cross sectional study was held in Baghdad teaching hospital from March 2017 to March 2018, consisted of patients with acute coronary syndrome(ACS) underwent 2D - STE for left ventricular regional longitudinal strain(RLS) immediately before invasive coronary angiography .Results : Fifty patients who fulfilled the inclusive criteria were enrolled in this study. The mean age 57.2 (± 7.9) years; and male : female ratio 1.9 : 1. Regional Longitudinal strain - speckle tracking showed 38 patients had CAD and 12 patients had no CAD, Versus coronary angiography which showed 29 patients had CAD while 21 patient had no CAD or non significant lesions.The validity of RLS according to coronary angiography showed sensitivity 100%, specificity 57.1% ,PPV 76.3%,NPV 100%, and accuracy 82%.Conclusion : The current study revealed that (RLS) Speckletracking echocardiography technique has high sensitivity but with relatively low specificity in diagnosis of coronary artery disease in patient with acute coronary syndrome.

صلاحية فحوصات الفسلجة العصبية بتنبؤ شدة متلاكمة غوليان باري وباستحقاق التنفس الاصطناعي == Validity of neurophysiological study in prediction of severity of Guillain - Barre syndrome and the indication for mechanical ventilation

Author name: بلال صادق عبد الباقي
Supervisor name: نجیب حسن محمد | زكي نوح حسن
General topic: Medicine
Specific topic: Neurophysiology
Degree: Master
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Guillain - Barre syndrome is an acute monophasic, non - febrile postinfectious illness manifesting as ascending weakness, and areflexia.However, sensory, autonomic and brainstem abnormalities may also seen. It is one of the most common causes of acute motor paralysis. In addition to the clinical presentation, those patients may develop neurophysiological features suggestive of demyelinating neuropathy.However, an axonal form had been reported. Hence, the importance of electrophysiological study; nerve conduction study (NCS) and electromyography (EMG) in the neurological evaluation of the severity of Guillain - Barre syndrome and the indication for mechanical ventilation.This study aimed to evaluate the neurophysiological study in prediction the severity of GBS, assess the usefulness of neurophysiology in prediction of respiratory muscles involvement and find out whether the neurophysiological study of peripheral nerves can predict the indications of mechanical ventilation.Two groups of patients are involved in this study. 22 Patients with GBS in the neuromedical wards and 18 patients in the respiratory care units (RCU).The mean age of the two groups were (47+\ - 24 years) with female predominance (1.22 : 1).Each patient submitted to brief medical history, clinical examination and neurophysiological study. This study was conducted at the neuromedical wards and RCU departments of Hospital of neurosciences, Baghdad and ALyarmuk teaching hospitals in a period from December 2017 to June 2018.The neurophysiological assessments involve the following tests : 1. Sensory NCS of bilateral median, ulnar and sural nerves involve sensory latency and sensory nerve action potential (SNAP). 2. Motor NCS of bilateral median, ulnar, common peroneal and tibial nerves involve the motor latency, compound motor action potential (CMAP), motor nerve conduction velocity (MNCV), conductions block and temporal dispersion.3. Minimal F wave latency of bilateral median, ulnar, common peroneal and tibial nerves.4. Needle EMG for bilateral proximal and distal muscles of upper (first dorsal interosseous) and lower limbs (tibialis anterior and extensor digitorium brevis) in which insertional activity, spontaneous activity, motor unit action potential MUAP and interference pattern were applied.The results of this study reveal that F wave and distal motor latencies of the left median, left ulnar, left peroneal, left tibial, right ulnar, right peroneal and right tibial nerves are significantly different between studied groups. Where there are prolonged latencies which could be considered as an indicator for admission to the RCU.Moreover, the reduced compound motor action potential (CMAP) and decrease conductive velocity (CV) in nearly all nerves are significantly different between studied groups and can also increase the chance for admission to the RCU.Concerning sensory abnormalities recorded in this study there are a reduced sensory nerve action potential of left median nerve or a prolonged left ulnar sensory latency when compared to the right ulnar and median sensory study and also increase the risk for admission to the RCU. Interestingly, what was noticed in this study, there are asymmetrical findings in nerve conductive parameters of the same patient involving not only the motor nerves rather than the sensory nerves too.This study concluded that the neurophysiological study can predict the severity of Guillain - Barre syndrome mainly the prolongation of F wave and motor latencies. The peripheral neurophysiological findings are useful in prediction of respiratory muscles involvement by GBS depending on CMAP and conductive velocity. There are asymmetrical finding changes in the studied neurophysiological parameters more apparently involving the sensory nerves of the same patients. Extremes of an age (<30yrs and >50yrs) represent a risk factor if not an indicator for RCU admission.

تعدد الاشكال الجيني للكالكتين - ? في مرضى التهاب المفاصل الروماتويدي == Galectin - 8 Gene Polymorphism In Rheumatoid Arthritis Patients

Author name: طارق قادر طلاب
Supervisor name: محمد عبد الاخوة الفحام | فائق ايشو كوريال
General topic: Medicine
Specific topic: Microbiology - Immunology
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: التهاب المفاصل الروماتويدي هو مرض التهاب المفاصل الالتهابي المزمن مع معدلات كبيرة للمراضة والوفيات .التشخيص المبكر مهم للمعالجة وتحقيق افضل النتائج . لقد اجريت هذه الدراسة في الفترة ما بين بداية تشرين الثاني عام 2016 وحتى نهاية تشرين الثاني عام 2017 على 90 شخصا تم تشخيص 50 منهم على انهم مصابين بالتهاب المفاصل الروماتويدي (مجموعة المرضى) الذين كانوا يحضرون للعيادة الخارجية للمفاصل بمستشفى بغداد التعليمي وكان هناك ايضا 40 اخرون من مجموعة الاصحاء. تم جمع عينات الدم من المرضى والاصحاء لاكتشاف تعدد الاشكال الجيني للكالكتين - 8 والذي تم اجراؤه بواسطة تفاعل سلسلة البوليميريز الخاص بتضخيم الطفرة (ARMS - PCR)كما تم تقييم مستوى الكالكتين - 8 والاجسام المضادة لل CCP في مصل الدم بواسطة مقايسة الممتز المناعي المرتبط بالانزيم ELISA)). تم قياس بروتين سي التفاعلي( CRP) بواسطة nephlometer كما تم فحص العامل الروماتويدي RF) ) بواسطة طريقة تراص اللاتكس . كان مجموع مرضى الدراسة الحالية 50 مريضا، كان متوسط اعمارهم (10.4±46.5) سنة ، وكانت نسبة الاناث سائدة اكثر من الذكور في نسبة (F : M 2.6 : 1). لقد اوضحت الدراسة الحالية انه لم يكن هناك اختلاف كبير بين المرضى والاصحاء في ما يتعلق بتعدد الاشكال الجيني للكالكتين - 8 وكشفت الدراسة الحالية ان مستوى الكالكتين - 8 كان اعلى في مجموعة الاصحاء (87.83 ± 182.93) من مجموعة المرضى ( 36.68± 25.79 ) وهذا الفرق ذو دلالة احصائية (P<0.001 ) ,في ما يتعلق بالاجسام المضادة للCCP فقد تم اكتشافها في 45 من المرضى بينما كانت سالب في جميع عناصر مجموعة الاصحاء والفرق كان ذو دلالة احصائية P <0.001 ) ) ,كما اظهرت الدراسة ان بروتين سي التفاعلي كان موجبا في 25 مريضا وفي 11 فردا من مجموعة الاصحاء وهذا الفرق ذو قيمة احصائية (p= 0.03), كما كشفت النتائج الحالية ان اختبار العامل الروماتويدي كان موجبا في 25 مريضا وكذلك 9 افراد من مجموعة الاصحاء وهذا الفرق ذو دلالة احصائية (p= 0.007) ,كما ان معدل ترسيب الدم لمجموعة المرضى اعلى من مجموعة الاصحاء وذو دلالة احصائية عالية (P <0.0001 ) . لقد اوضحت الدراسة انه لم يكن هناك اي اختلاف ملحوظ بين مجموعة المرضى ومجموعة الاصحاء فيما يتعلق بتعدد الاشكال الجيني للكالكتين - 8كما بينت الدراسة ان لمستوى الكالكتين - 8 في مصل الدم نتائج ممتازة للتمييز بين مجموعة المرضى ومجموعة الاصحاء.ان مستويات الكالكتين - 8 كانت اعلى في مجموعة الاصحاء من مجموعة المرضى , كان هناك ارتباط كبير سلبي بين مستويات الكالكتين - 8 والاجسام المضادة للCCPومعدل ترسيب الدم والعامل الروماتزمي وهذا يشير الى ان مستوى منخفض من الكالاكتين - 8 يرتبط بشكل كبير مع مستوى عال ( مستوى متزايد) من الاجسام المضادة للCCPومعدل ترسيب الدم والعامل الروماتويدي ، وبالتالي يمكن ان يشير الى نشاط المرض وشدته. | Rheumatoid arthritis is chronic inflammatory arthritis disease with significant morbidity and mortality .Early diagnosis is important for beter treatment and outcome. Galectins are potent immune regulators and modulate a range of pathological processes, such as inflammation, autoimmunity, and cancer, Accumulated evidence shows that several family members of galectins play positive or negative roles in the disease development of RA, through their effects on T and B lymphocytes, myeloid lineage cells, and fibroblast - like synoviocytes. This case controls study assess the association between serum galactin - 8 gene polymorphism in RA and controls .And also measure the serum level of Galectin - 8 in RA patient and controls and its validity in early diagnosis. Patients and Methods : This study was conducted in the period between November 2016 till the end of November 2017 on ninety (90) subjects, fifty (50) of them (patient group) were diagnosed as established RA patients, who were attending the Rheumatology Outpatient Clinic of Baghdad Teaching hospital, and other forty (40) were apparently healthy control group. Blood samples were collected from patients and controls to assess serum galectin - 8 and ACCP by enzyme linked immunosorbent assay (ELISA), the CRP was measured by nephlometer, and RF by latex agglutination method, Whereas Galectin - 8 gene Polymorphism done by Amplification - Refractory Mutation System - PCR (ARMS - PCR).Results : 50 case study group included in the current study, their mean age 46.5±10.4 years, the females were predominant than males in a ratio (F : M 2.6 : 1). The current study revealed that serum levels of galectin - 8) higher in control group (182.93±87.83) than patient group (36.68±25.79) and this difference is statistically significant (P - value < 0.001).At the optimum cut off value of serum gal - 8 ≤ 95.7 we found that maximum accuracy was 95.6 , sensitivity 98.0%, specifity 92.5% and AUC was 0.971 this indicate that the biomarker has excellent valid results to differentiate bet patient and control. In the present study there was negative significant correlation between serum galectin - 8 and ESR,ACCP,RF. there was no significant difference between patients and controls regarding galectin - 8 gene polymorphism. TT allele had the highest association with RA while AT allele had the weakest association with RA, however; all these alleles did not associated significantly with RA.Anti - CCP antibodies were detected in 45 (90.0%) patients and were not detected only in 5 (10.0%) patients. Out of 40 healthy controls; the anti - CCP was negative in all healthy controls (100.0%), , with extremely statistical difference (P <0.001) between the patients and healthy control group. The present study showed that CRP was positive in 25 patients (50.0 %), and in 11 subjects (27.5%) from control group and this difference is statistically significant p - value= 0.03The present findings revealed that RF test was positive in only 25 patients (50.0%), and was positive in nine subjects (22.5%) from control group and this difference was statistically significant (P - Value = 0.007 ), Mean level of ESR of patient group higher than control group and is highly statistically significant (P - Value < 0.0001).Conclusions : The study shown that there was no significant difference between patient and controls regarding galectin - 8 gene polymorphism, and there was significantly less serum galectin - 8 in patient compared to control, also there was negative significant correlation between serum galectin - 8 and ESR,ACCP,RF.At the optimum cut off value of serum gal - 8 ≤ 95.7 we found that maximum accuracy was 95.6 , sensitivity, specifity and AUC was 0.971 this indicate that the biomarker has excellent valid results to differentiate between patient and control

تاثير التدخين المزمن على وظائف البطين الايمن للقلب لدئ فئة الذكور الشباب : دراسه صدئ القلب بطريق تعقب الوصلة النقطية للاجهاد == The Effects of Chronic Cigarette Smoking on the Right Ventricular Functions in Young Male Subjects : A Speckle Tracking Echocardiographic Study

Author name: شهيد حميد عيدان
Supervisor name: معتز فوزي حسين
General topic: Medicine
Specific topic: Diseases - Heart
Degree: Higher Diploma
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: الخلفية : يعتبر التدخين المزمن واحدا من اهم عوامل الخطورة للاصابة بامراض الشرايين التاجية ومع ذالك فان له تاثيرات جانبية اخرى على القلب غير معتمدة على تصلب الشرايين.الهدف من هذه الدراسة : لتقييم الاعراض الجانبية المحتملة من التدخين المزمن على وظاىف البطين الايمن للقلب الانقباضية والانبساطية بتعقب الوصلة النقطية للاجهاد بواسطة جهاز صدى القلب ثنائي الابعاد.طرائق البحث : تم اجراء هذه الدراسة في مستشفى بغداد التعليمي شعبة القسطرة \وحدة الايكو للفترة من حزيران 2017 الى ايار 2018 .حيث تم تقسيم المشاركين الى مجموعتين ,مجموعة المدخنين ومجموعة غير المدخنين وتم اجراء فحص صدى القلب للماشركين حسب البروتوكول القياسي ومن ثم تعقب الوصلة النقطية للاجهاد بواسطة صدى القلب ثنائي الابعاد لتقييم الاجهاد الطولي العام للبطين الايمن من القلب . النتائج : اربعين حالة من الذكور الشباب مع اربعين حالة مراقبة مطابقة في العمر تم تسجيلهم في هذه الدراسة حيث كانت الخصائص الاساسية لكلا المجموعتين متشابهة.وكان هنالك اختلاف بشكل ملحوظ للانحراف الانقباضي للحلقة الطائرة لثلاثي الحراشف (قيمه 0.04 > P) حيث انه كان منخفض بشكل ملحوظ لدى مجموعة المدخنين. قمة السرعة الانبساطية المتاخرة( موجه A )كانت مرتفعة بشكل ملحوظ لدى مجموعة المدخنين (قيمه 0.016 > P) وبالتالي فان نسبة قمة السرعة الانبساطية المتقدمة الى قمة السرعة الانبساطية المتاخرة كانت منخفظة بشكل ملحوظ لدى هذه المجموعة(قيمه 0.017 > P). ان تصوير الدوبلر للانسجة لجدار البطين الايمن الحر اظهر ان قمة السرعة الانقباضية لجدار البطين الايمن الحر وقمة السرعة الانبساطية كانتا منخفظتان بشكل ملحوظ لدى مجموعة المدخنين مقارنة بمجموعة المراقبة(قيمه 0.02 > P للحالتين ). وان الاجهاد الطولي العام كما تم تقييمه بتعقب الوصلة النقطية للاجهاد بواسطة جهاز صدى القلب ثنائي الابعاد كان منخفظا بشكل ملحوظ لدى مجموعة المدخنين (قيمه 0.04 > P). كانت هنالك علاقة مترابطة بشكل ملحوظ بين كمية التدخين والاجهاد العام للبطين الايمن بتعقب الوصلة النقطية للاجهاد بواسطة جهاز صدى القلب ثنائي الابعاد.الاستنتاج : اظهرت هذه الدراسة ان التدخين المزمن يسبب تغييرات في الوظائف الانقباضية الطولية والوظائف الانبساطية لبطين القلب الايمن لدى فئة الذكور الشباب وان هذه التغييرات يمكن اكتشافها بصورة مبكرة بتعقب الوصلة النقطية للاجهاد بواسطة صدى القلب ثنائي الابعاد. | Background : Chronic Cigarette smoking is one of the major risk factors for coronary artery disease. However, it has additional cardiac adverse effects independent of coronary atherosclerosis.Objectives of study : To assess the effects of chronic smoking on right ventricular systolic and diastolic functions using Two - Dimensional Speckle Tracking.Patient and methods : This study was carried out in Baghdad Teaching Hospital\ Echo unit from June 2017 to May 2018.The participants whom divided into two groups smoker vs nonsmoker were examined by standard echocardiography protocol which was followed by Two - Dimensional Speckle Tracking to assess the functions of the right ventricle.Results : Forty young smokers’ men and 40 age - matched nonsmoking controls enrolled in this study, the baseline characteristics of two groups were similar. There were significant differences regarding the Tricuspid Annular Plane Systolic Excursion ,P (<0.04) which were significantly reduced in smokers group. The peak late diastolic velocity (A wave) were significantly higher in smoker group P (0.016) and hence the E/A ratio were significantly lower P (0.017). The Tissue Doppler Imaging examination of right ventricular free wall reveal that the Peak systolic velocity of RV free wall (S’), and the peak early diastolic velocity of RV free wall (E’) were found significantly lower in smokers group when compared to control group (P <0.02 for both ). The Global Longitudinal Strain as assessed by 2D - Speckle Tracking Echocardiography were also significantly reduced in smoker group P (0.04). There were significant correlations between the amount of smoking and right ventricular global strain by 2 - D Speckle Tracking Echo study.Conclusion : This study demonstrated that chronic cigarette smoking causes alterations in long - axis systolic and diastolic functions of right ventricle in healthy young subjects. These changes can be early detected with 2 - D Speckle Tracking Echocardiography

تقييم التشخيص الكهروفسلجي الناتج عن خلل الوظيفة اللا ارادية في مرضى داء السكري == ELECTRODIAGNOSTIC EVALUATION OF AUTONOMIC DYSFUNCTION IN DIABETES MELL

Author name: نهال مهند لطفي
Supervisor name: عبد الناصر حسين امير
General topic: Medicine
Specific topic: Physiology
Degree: Master
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: Diabetic autonomic neuropathy is a serious and common complication of diabetes. The most studied and clinically important form of diabetic autonomic neuropathy is cardiovascular autonomic neuropathy.Aim of study : To assess the autonomic dysfunction in diabetics electrodiagnoctically using reliable tests by sympathetic skin response and R - R interval tests.A cross - sectional study was conducted in the Electromyography unit in Baghdad Teaching Hospital between (Feb/1/2018 - May/15/2018). It included all adult male and female with symptoms of neuropathy or autonomic dysfunction. Pregnant women were excluded from the study. Neurological tests were performed as sympathetic skin response, and R - R interval including normal and deep breath, Valsalva and tilt tests).Means of sympathetic skin response amplitude, R - R interval (Valsalva), and R - R interval (tilt) tests were significantly higher in non - diabetic patients than diabetics (2.19 versus 0.541, P= 0.001; 1.75 versus 1.48, P= 0.017; and 1.44 versus 1.01, P= 0.002 respectively). They were also significantly higher in controlled than in uncontrolled diabetic patients (1.69 versus 0.15, P= 0.044; 1.99 versus 1.31, P= 0.039; and 1.23 versus 0.941, P= 0.022 respectively). Cut points of these tests between controlled and uncontrolled diabetic patients were (0.81, 1.84, and 1.04 respectively). This mean that all patients with tests below these values can be considered uncontrolled diabetics.Sympathetic skin response amplitude, and R - R interval tests are good electro diagnostic tests to evaluate the autonomic dysfunction affected by diabetes, and to assess the severity of autonomic dysfunction in uncontrolled diabetes and differentiating them from those with controlled diabetes.

التقييم الوظيفي للبطين الايمن في مرضى ارتفاع الضغط الشرياني باستخدام تقنية شدة صدى القلب == Physiological Assessment of Right Ventricular Function in Patients with Systemic Hypertension Using Strain Echocardiography

Author name: حيدر عامر توفيق
Supervisor name: حنان لؤي العمري | غازي فرحان حاجي
General topic: Medicine
Specific topic: Physiology
Degree: Doctorate
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: البطين الايمن او البطين المنسي هو عبارة عن حجرة ذات شكل غير منتظم وتركيب هندسي معقد . على الرغم من ان التركيز كان في السابق على الجزء الايسر من القلب من الناحية الوظيفية والمرضية ، فهناك عدد متزايد من الادلة على اهمية البطين الايمن وخاصة اهميته في الحفاظ على استقرار الدورة الدموية للجسم ، مستوى النشاط في المرضى الذين يعانون من قصور القلب المزمن ومدى التحسن في المرضى الذين يعانون من امراض صمامات القلب.ارتفاع ضغط الدم الشرياني هو مشكلة صحية عامة رئيسية واسعة الانتشار على المستوى العالمي. تعرف امراض القلب الناتجة عن ارتفاع ضغط الدم باعتلال عضلة القلب الناتجة عن استجابة عضلة القلب للاجهاد الميكانيكي الناتج عن ارتفاع ضغط الدم وتاثير الهرمونات العصبية وعوامل النمو التي تؤدي الى تشوهات متنوعة تشمل تضخم البطين الايسر , الاضطراب الانقباضي والانبساطي ، ومضاعفاتها السريرية بما في ذلك عدم انتظام ضربات القلب وقصور القلب.في دراسة صدى القلب للبطين الايمن ، يجب اجراء التقييم الشامل باستخدام نوافذ صوتية متعددة وتقنيات مختلفة. ان طريقة تتبع البقع الصغيرة باستخدام تخطيط صدى القلب ثنائي الاتجاه هي طريقة جديدة لحساب تشوه عضلة القلب في الصور القياسية ذات المقياس الرمادي حيث كل قطعة صغيرة من عضلة القلب في صورة تخطيط صدى القلب لديها نمط فريد خاص بها من البقع.كان الهدف من هذه الدراسة هو : تقييم تاثير ارتفاع ضغط الدم الشرياني على وظيفة البطين الايمن الانقباضي والانبساطي مقارنة مع المجموعة الضابطة وتحديد تاثير ارتفاع ضغط الدم الشرياني على ميكانيكة البطين الايمن بقياس قيمة التشوه الطولي ثنائي البعد .وكان العدد الاجمالي المشمول في الدراسة ( 200 ) شخص من كلا الجنسين ( 118 من الرجال و82 من الاناث ) ، تتراوح اعمارهم من ( 40 - 60 ) سنة ، وتم تقسيمهم الى مجموعتين : 1 - 100 شخص من المرضى الذين يعانون من ارتفاع ضغط الدم الشرياني . 2 - 100 شخص من الاشخاص الاصحاء يمثلون المجموعة الضابطة. وقد تم اخذ التاريخ الطبي الكامل ، تخطيط القلب الكهربائي , قياس ضغط الدم , تصوير الصدر بالاشعة السينية وقياسات الطول والوزن لكل الاشخاص , تم اجراء تخطيط صدى القلب لجميع الاشخاص باستخدام جهاز GE Vivid E9® .نتائج هذه الدراسة اكدت وجود فرق معتد من الناحية الاحصائية فيما يتعلق بوظيفة البطين الايمن الانبساطية بين مجموعة المرضى والمجموعة الضابطة ( P = 0.001 ) .وفيما يتعلق في قياس قيمة التشوه في البطين الايمن كذلك اكدت الدراسة انخفاض قيمة التشوه في البطين الايمن للمرضى مقارنة بالمجموعة الضاغطة وكان الفرق معتد من الناحية الاحصائية ( P = 0.001 ) .و كشفت الدراسة ان نسبة الارجحية من الانحدار اللوجستي متعدد المتغيرات ان سمك الحاجز بين البطينين كان المؤثر الاكبر على قيمة التشوه في البطين الايمن .نتائج هذه الدراسة وضحت انخفاض نسبة التشوه الطولي للبطين الايمن وبالتالية تاثر الوظيفة الانقباضية عند مجموعة المرضى وعلاقة هذا التاثر القوية مع تضخم الحاجز بين البطينين الشيء الذي لم تستطع الفحوصات التقليدية في اكتشافه | The right ventricle or the forgotten chamber is multi - compartmental in orientation with a complex structural geometry. Although the focusing in cardiology was placed on left heart physiology and pathology in the past, there is a growing body of evidence for the importance of the RV especially the maintenance of normal body hemodynamics, exercise capacity in chronic heart failure and survival in patients with valvular heart disease. Arterial hypertension is a major public health problem due to its high prevalence globally. Hypertensive heart disease is the cardiomyopathy which result from myocardial response to the mechanical stress from elevated blood pressure , the influences of neurohormones , growth factors, and cytokines and then leads to variety of abnormalities includes left ventricular hypertrophy (LVH), systolic and diastolic dysfunction, and their clinical complication including arrhythmias and heart failure .In echocardiographic studies, a comprehensive assessment of the right ventricle should be performed using multiple acoustic windows and different image techniques .The two dimensions speckle tracking echocardiography is a novel non - invasive echocardiographic method to calculate myocardial deformation in standard grey - scale images in which every little piece of myocardium in echocardiography image has its own unique pattern of speckles. The aim of this study was to : evaluate the effect of systemic arterial hypertension on systolic and diastolic right ventricular function and to determine the effect of systemic arterial hypertension on right ventricle mechanics using two dimensional longitudinal strains.The total number of hypertensive patients and apparently healthy control subjects were (200) of either sex (118 male and 82 female), their age range from (40 - 60) year; they were divided into two groups : 100 Patients with hypertension, 100 apparently healthy control subjects. Each patient and control subject was submitted to full medical history, physical examination, ECG, chest X - Ray, blood pressure determination and subject’s anthropometry measurements. Echocardiography was performed for all subjects using a GE Vivid E9® system in which M - mode, two dimensional , color, pulse and continuous wave Doppler , tissue Doppler and speckle tracking imaging were obtained according to the American Society of Echocardiography guideline of using Echocardiography in Adult Hypertension.Trans - tricuspid E/A ratio was decreased in hypertensive group (1.10±0.12) versus (1.39±0.28) in normotensive group with statistically significant difference p value =0.001. The mean tricuspid E/ é ratio was (4.95±1.34) in hypertensive patients while was (3.90±0.98) in control group, the p value was 0.001 and there was significant difference between them. It was observed that the mean 2D - RVGLS was ( - 20.12 ± 3.80) % in hypertensive patients versus ( - 25.90 ± 2.18) in normal subjects, the P value was 0.001 and there was significant difference between the two groups. The odds ratio of multivariate logistic regression revealed that the diastolic interventricular septum thickness was the strongest factor affect RVGLS in this study, odds ratio for IVSD, RWT, and LVPW were respectively 2.418, 1.978, and 1.761. This study conclude that RV longitudinal strain is significantly impaired in hypertensive patients group and strongly correlates with heart remodeling and it is superior to more conventional functional parameters of RV systolic function.

دراسة تنشيط النطف البشرية باستخدام الوسط الزرعيHam's F - 12 ومادة البومين المصل البشري لمرضى العقم == An in vitro human sperm activation study Using Ham’s F - 12 medium and human serum albumin for infertile patients

Author name: محمد حسن شعبان
Supervisor name: محمد باقر محمد رشاد فخر الدين
General topic: Medicine
Specific topic: Obstetrics and Gynecology
Degree: Higher Diploma
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: تهدف هذه الدراسة الى التحقق من كفاءة الوسط الزرعي (Ham's F - 12) كوسط لتحضير النطف, كذلك فعالية مادة البومين مصل الدم البشري ( (Human serum albumin; HSA كمادة منشطة للنطف لاستخدامها في عمليات التنشيط لمرضى العقم. شملت هذه الدراسة مائة واربعون مريضا من المصابين بالعقم بسبب وهن النطف(Asthenozoospermia) او قله عدد النطف) (Oligozoospermiaاو كلاهما) (Oligoasthenozoospermia. كان معدل اعمارهم هو) 4.32±35.62 (عاماومعدل فترة العقم هو (6.06±0.22) سنة. تمت الدراسة في مستشفى الحسين العام وعيادة المصطفى الطبية الشعبية في كربلاء واستغرقت للفترة من شهر تموز 2006 الى شهر تشرين الثاني 2006 .تم تنشيط النطف خارج الجسم ( (in vitro sperm activation حيث استخدم الوسط الزرعي ( (Ham's F - 12 كمجموعة سيطرة(ضابطة) واستخدمت ثلاث تراكيز من مادة ( (HSA 5% و7.5% و10% وبفترتي حضن 15 و30 دقيقة. قسمت نماذج المني الى قسمين حيث حضرت المجموعة الاولى( 70 نموذج ) بتقنية النبذ والسباحة Centrifugation swim - up technique)) والسبعون الاخرى بتقنية السباحة المباشرة (Direct swim - up technique).تم فحص السائل المنوي لجميع المرضى قبل عملية التنشيط ثم قورنت النتائج مع نتائج بعد التنشيط ولجميع المرض وقورنت كذلك بعد استخدام التراكيز الثلاث المضافة من مادة ( (HSA . اظهرت النتائج ايجابية الوسط الزرعي Ham's F - 12) )لاستخدامه كوسط لتحضير النطف حيث لوحظ زيادة في حركة النطف , وكذلك زيادة في نسبة فعالية النطف A,B وكذلك زيادة في نسبة النطف السوية . كذلك لوحظ زيادة في حركة ونسبة فعالية النطف A, B وزيادة في نسبة النطف السوية ايضا بعد اضافة مادة ( (HSA وكان التركيز الافضل هو 5% وبفترة حضن 30دقيقة . وان افضل النتائج كانت للمرضى المصابين بوهن النطف مقارنة مع نتائج المرضى المصابين بقلة النطف او بقلة ووهن النطف. نستنتج من هذه الدراسة ان الوسط الزرعي Ham's F - 12) ) ذو فعالية جيدة كوسط لتنشيط النطف كما ان مادة الالبومين( (HSA يمكن استخدامها كمادة منشطة للنطف للمرض المصابين وهن النطف. | medium as sperm preparation medium and the effectiveness of human serum albumin HSA as sperm stimulator in in vitro human sperm activation for infertile patients. One hundred forty (140) infertile males were shared in present study. The mean ages of infertile males were 35.62± 4.32 years. The mean duration of infertility of them was 6.06 ±0.22 years with range of 1 - 11 year.Ham’s F - 12 medium was used as control group and three different concentrations of HSA were used (5%, 7.5% and 10%), with two incubation periods (15 and 30 minuets). Seventy semen samples were prepared using centrifugation swim - up technique, and the other seventy semen samples prepared using direct swim - up technique. The comparison was done between parameters of semen of all treated groups post - activation with pre - activation parameters and control group (Ham’s F - 12 medium).The results of the present study showed that a significant improvement in seminal fluid analysis parameters especially sperm concentration, percentage of sperm agglutination and round cells concentration were reduced significantly (P<0.01) in both technique. In contrast, percentages of sperm motility, progressive sperm activity (grades A and B) and normal sperm morphology were increased significantly (P<0.05) using both techniques.With the usage of Ham’s F - 12 medium also significant enhancement were reported in compared to pre - activation Sperm concentration, sperm agglutination percentage and round cells concentration were reduced significantly(P<0.01) in both techniques. On the other hand, percentage of sperm motility, percentage of progressive sperm activity (grades A+B) and normal sperm morphology (%) were increased significantly (P<0.05) using both techniques.The results showed that the addition of HSA to the culture medium enhances sperm motility (%), percentage of progressive sperm activity (grades A and B) and normal sperm morphology (%) using both techniques. Moreover, the best results were reported with 5% HSA and 7.5% HSA after 30 minutes of incubation. In addition to that, the results of sperm activation were better with asthenozoospermic patients than oligozoospermic and oligoasthenozoospermic patients

قياس جودة الاشعة السينية الرقمية لاشعة الصدر في مستشفيات مدينة الناصرية 2018م/1440هـ == Quality Assessment of digital Chest radiography in Al Nasiriyah Main Hospitals at 2018/1440H

Author name: رياض عادل عبد العزيز
Supervisor name: Muslim Nah. Saaeed
General topic: Medicine
Specific topic: Family Medicine
Degree: Higher Diploma
University: University of Thi-Qar - Faculty Of Medicine
Language: English
University location: Dhi Qar
First pages:
Abstract: الخلفية : يحق لطبيب الاسرة في حالات متكررة ترتيب وتقييم وتفسير وتشخيص صور الاشعة السينية بنفسه وبدون توجيه مهني متخصص من اخصائي الاشعة. جودة الاشعة السينية هي العنصر الاساسي لتسهيل التشخيص وزيادة دقة العلاج، من خلال القيام بذلك، فهي توفر اقصر الطرق للتعافي.الهدف : هدفت هذه الدراسة الى تقييم جودة الصور الشعاعية للصدر لتقييم كفاءة فنيي الاشعة في مستشفيات الناصرية الرئيسية : مستشفى الحسين، والحبوبي بنت الهدى.المواد والطرق : دراسة مقطعية بصورة رجعية، اجريت لمدة ثلاثة اشهر، من الاول من حزيران / 2018 حتى 31 اب / 2018، في ثلاثة مستشفيات جامعية في مدينة الناصرية / جنوب العراق. شملت العينة عينة من 711 صدر اشعة سينية الرقمية ، تم تقييمها لمعلمات الجودة من قبل اثنين من اطباء الاشعة من نفس المستشفى الذي تم اخذها منه.النتائج : كان معدل الرفض للاشعة السينية على الصدر 20.25 ٪، حيث كان هناك 144 من اصل 711 فيلما لم تجب على السؤال السريري، وتحتاج الى تكرار. تقريبا نصف الافلام المرفوضة كانت من بنت الهدى مع 70 (48.6٪) من الافلام المرفوضة. اعلى معدل للرفض كان سببه : تناوب مع 29 (20.14 ٪)، والتنغيم مع 28 (19.44 ٪) وخطا الاختراق 26 (18.06 ٪). سوء التنفس هو السبب الرئيسي للرفض في 15 (10.42 ٪) من الافلام، وقطع الاشتمال التشريحيAnatomical inclusion في 15 (10.42).الاستنتاجات : كان هناك معدل رفض الاشعة السينية الصدر (20.25 ٪) في المستشفيات الثلاثة. تشمل اكثر الاسباب شيوعا خطا الموقع (الدوران في 29 (20.14٪) وسوء التنفس في 28 (19.44٪)، اخطاء الاختراق في 26 (18.06٪)، اما مستشفى بنت الهدى فكانت الاكثر شيوعا في رفض الاشعة السينية (48.6). ٪). توافد عدد كبير من المرضى والتحميل الزائد في تلك المستشفيات، نتجت باخطاء تشخيصية مع ارتكاب العديد من الاخطاء في جودة الاشعة السينية للصدر. | Background : the the family physician is entitled in frequent situations to order, evaluate, interpret, and diagnose chest X - rays by himself and without professional guidance of a specialized radiologist. Quality of X - rays is the key element for facilitating the diagnosis and increase the accuracy of treatment, by doing that it provides the shortest way to recovery.Aim : This study aimed for assessing the quality of chest radiography in AlNasiriyah main hospitals; Al - Hussein, AlHabbobi, and Bent AlHuda Hospitals.Material and methods : Observational prospective cross sectional study, done for a period of three months, from the First of June/2018 until the 31st of Ougest/2018, in three tertiary hospitals in AlNasiriyah city/ South of Iraq. It included a total sample of 711 chest X - rays, assessed for quality parameters by two radiologists from the same hospital it was taken from. Results : there were 144 out of 711 films that did not answer the clinical question, and needed to be repeated. Almost half of rejected films were from Bent Al - Huda with 70(48.6%) rejected films. The variables that had the highest odds for rejecting an X - ray film were having an obese body built, angulated films, aftifacts and incomplete inspirationConclusions : There was a chest X - ray rejection rate of (20.25%) in the three hospitals. The most common causes included positioning fault (rotation in 29(20.14%) and angulation in 28(19.44%), and penetration errors in 26(18.06%). Bent AlHuda Hospital had the most frequent rejected X - rays of (33.9%). Large number of patients and resulting loading in those hospitals interfered with diagnosing their diseases and made several mistakes in chest X - ray quality

تقييم كثافة المعادن العظمية وكتلة العجاف والكتلة الدهنية في المراة قبل وبعد انقطاع الطمث : دراسة مقارنة == Evaluation of Bone Mineral Density, Lean Mass and Fatty Mass in Pre and Postmenopausal Women A Comparative Study

Author name: علي حسين فالح
Supervisor name: غسان ثابت سعيد | فائق ايشو كوريال
General topic: Medicine
Specific topic: Physiology
Degree: Higher Diploma
University: University of Baghdad - Faculty Of Medicine
Language: English
University location: Baghdad
First pages:
Abstract: The body composition (BC) describes the different components that makeup the human being and refers to the proportion of fat and fat - free mass inthe body. Aging processes are natural complex physiological alteration in thebody associated by weakness of the structure and functions in the organs.The alterations in body composition that occur with the aging process nothappen homogeneously. Although there are various techniques forassessment of body composition in research and clinical settings, DualX - ray absorptiometry (DXA) is the most commonly used methods forexamination and also preferred choice and golden clinical tool for thediagnosis of osteoporosis and assessment of its severity. This equipment isnoninvasive, widely available and currently the scanning of hip and spineused as the gold standard by a major number of clinicians. In recent years,there has been an increasing interest in BC measurement to assess the health.This is the first study in Iraq to assess healthy subjects.Objectives : to evaluate the changes of bone mineral density and fatty massand lean mass in postmenopausal period and to correlate them withanthropometric measurements. Also to correlate between BMD with serumcalcium, phosphate and alkaline phosphatase.Subjects and methods : This cross - sectional study was conducted at DXAUnit in Baghdad Teaching Hospital from November 2016 to December2017. Data were collected from (120) postmenopausal female subjects and(120) premenopausal female subjects with total of 240 females from age of40 - 69 years were randomly selected from the patients attending DXA unit inBaghdad Teaching Hospital. The postmenopausal female subjects weredefined as individuals with menopause at least one year since the last naturalmenstruation. Osteoporosis was diagnosed according to WHO criteriaIIT - score was used for postmenopausal subjects and Z - scores forpremenopausal subjects. Women were excluded from the study if they anycondition may affect the BMD or other constituents of BC.Results : a highly significant lower BMD of lumbar spine and both femurswere found in postmenopausal group. Although the mean of areas of ribs, lumbar spine, pelvis, legs and total body fat mass were higher in postmenopausal subjects but no significantly differences of body fat mass g̸cm² measured by DXA between the postmenopausal and premenopausal subjects. A highly significant difference of LM g ̸cm² measured by DXA between the postmenopausal and premenopausal subjects (p - value0.0004 - 0.001) in measurements of total LM and anatomical areas. Significant effects were found of total FM and total LM on BMD of lumbar spine and neck of both femurs in postmenopausal subjects but LM had more effect than FM.Conclusion : A highly significant lower BMD and LM were found with increased adiposity among postmenopausal women. Both FM and LM affect BMD of lumbar spine and both femurs but LM had more effect
1 ... 168 169 170 171 172 ... 274