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معدل انتشار المقاومة البلازميدية لمضادات الكوينولون في العزلات السريرية لبكتيريا Klebsiella pneumoniae في مستشفيات النجف == Prevalence of Plasmid-Mediated Quinolones Resistance Genes in Clinical Isolates of Klebsiella pneumoniae in Najaf Hospitals

Author name: زينب جابر هادي

Supervisor name: علي محسن المحنة

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

تاثير الفالزارتان والرزوفاستاتين على التحوير المناعي بعد الاصابة بنقص التروية الدماغية واعادة الترويه == Effect Of Valsartan And Rosuvastatin On Immune Modulation After Brain Ischemia Reperfusion Injury

Author name: كحلاء كاظم عبد

Supervisor name: هاشم رحيم طارش | نجاح رايش الموسوي

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

الكشف عن انزيمات البيتالاكتاميز نوع OXA في بكتريا الزوائف الزنجارية المعزولة من مستشفيات النجف == Detection of OXA-Type ?-Lactamases in Pseudomonas aeruginosa Isolated from Al-Najaf Hospitals

Author name: علاء عبد الحسين رسول

Supervisor name: علي محسن المحنة

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

دراسة مناعية وجزيئية للافات الجلدية في النساء الحوامل المصابات بداء القطط == Immunological and molecular study of cutaneous lesions in pregnant women with Toxoplasmosis

Author name: رنا طالب فاخر النفاخ

Supervisor name: باقر عبيس سلطان | زينب حسن الخفاجي

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

دراسة جزيئية ومناعية لترافق وتاثير عصيات السل الرئوية سرطان المثانة == Molecular and Immunological Study for the Association and Effect of Mycobacterium tuberculosis on Urinary Bladder Cancer

Author name: زينا محمد عبد الحسين الشامي

Supervisor name: هاشم رحيم طارش | اسعد عبد الحمزة الجنابي

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

دراسة مناعية وجزيئية بداء المقوسات على بعض مستويات الحركيات الخلوية والهرمونات في النساء في محافظة النجف == Immunological and Molecular study of Toxoplasmosis on some levels of cytokines and hormones in women in Najaf province

Author name: هاشم علي عبد الامير الشريس

Supervisor name: علاء جواد حسن | هاشم رحيم طارش

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

دراسة جزيئية ومناعية لبعض جينات الملوية البوابية == Molecular and Immunological study of some virulent genes of Helicobacter pylori

Author name: اسراء سعيد عباس كاظم

Supervisor name: كريم ثامر مشكور

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

دور الاجسام المضادة الذاتية ، الحركيات الخلوية، اليللات التطابق النسجي في امراضية داء السكري == Role of the Autoantibodies, Cytokines, HLA - DR alleles in the pathogenesis diabetes mellitus

Author name: منظر علي عبد الرضا السعيدي

Supervisor name: حسين سرحان الجنابي | جعفر كاظم الموسوي

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

بعض الاختبارات الجزيئية والمصلية للكشف عن مرضى داء المقوسات لدى النساء اللاتي عانين اجهاضا == Some Serological and Molecular tests used to identify Toxoplasmosis among Women with Abortion

Author name: كريم غالي محمد

Supervisor name: سلمان عزيز الجبوري | باقر عبيس سلطان

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University of Kufa - Faculty Of Medicine

Language: English

University location: Najaf

First pages:

دراسة مناعية وبكتيرية حول زيادة قابلية الاصابة بالتهابات الجهاز التنفسي بين الاطفال المرضى بالداء الزلاقي (مرض حساسية القمح) == Immunological and Bacterological Study about the Increased Susceptibility to Respiratory Tract Infections Among Coeliac Diseased Children

Author name: سولاف عبد العظيم البكري

Supervisor name: ايفاد كريم الشبلي | مضر حسن نور

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Babylon - Faculty Of Medicine

Language: English

University location: Babylon

First pages:

تاثير التنوع الجيني ل 17-il في مرضى التدرن الرئوي في محافظة بابل == Effect of IL-17 Gene Polymorphism in Tuberculosis Patients in Babylon Province

Author name: مصطفى جواد عبد خضير

Supervisor name: محمد عبد كاظم السعدي | ايفاد كريم عبد الشبلي

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University of Babylon - Faculty Of Medicine

Language: English

University location: Babylon

First pages:

الايجاد المصلي والطفيلي للزحار الاميبي لدى المرضى المثبطين مناعيا والمصابين بالاسهال

Author name: معالي ابراهيم يونس

Supervisor name: نوفل ياسين الدباغ

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Al Mosul - Faculty Of Medicine

Language: English

University location: Mosul

First pages:

دراســة التجمع البكتيري الحيوي فـــي الانابيــب المستخدمـــــة والمصاحبــــة للاخماج المختلفة == A study of bacterial biofilm formed in tubes associated infections

Author name: زينة نزار ذنون الجليلي

Supervisor name: هيثـم محمد خليـل الحبيـب

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Al Mosul - Faculty Of Medicine

Language: English

University location: Mosul

First pages:

تاثير بعض المضادات الحيوية على تطور المقوسات الكوندية المعزولة في الفئران == Effect of Some Antimicrobial Chemotherapeutic Agents on the Development of Toxoplasma gondii in Mice

Author name: زياد حسن احمد الجادر

Supervisor name: عبد السلام محمد المختار

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Al Mosul - Faculty Of Medicine

Language: English

University location: Mosul

First pages:

تقييم فحص مستضد البروتين الحلقي السترولينيدي في التهاب المفاصل الرثواني == Evaluation of Anti-Citrullinated Cyclic Peptide Antibody in Rheumatoid Arthritis

Author name: زهراء عامر هاشم

Supervisor name: نوفل ياسين الدباغ

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Al Mosul - Faculty Of Medicine

Language: English

University location: Mosul

First pages:

زيادة نمو المبيضات في المرضى ذوي المناعة المنقوصة والحساسية للمضادات الفطرية == Candidal Overgrowth in Immunocompromised Patients and Antifungal Susceptibility

Author name: زهراء صديق قاسم

Supervisor name: مناهل محمد يحيى

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Al Mosul - Faculty Of Medicine

Language: English

University location: Mosul

First pages:

عزل جراثيم الزائفة الزنجارية في العزلات من مرضى عدوى المستشفيات والكشف عن المورثات المقاومة لمضادات البيتالاكتم وتحليل تتابع الجينات في محافظة البصرة.العراق == Isolation of Pseudomonas aeruginosa from Patients with Hospitalized Infection and Detection of ?-lactam Resistance with Their DNA Sequencing in Basra Iraq

Author name: صبا عدنان عبد الوهاب

Supervisor name: سندس صديق بكر | زكي عبد الجبار الفداغ

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University Of Basrah - Faculty Of Medicine

Language: English

University location: Basrah

First pages:

التمنيع الجيني ضد اللشمانية في الفئران المختبرية نوع Balb/c == Genetic Immunization Against Leishmaniasis In Balb/c Mice Model

Author name: وميـض هاشــم عباس

Supervisor name: ناظم كاظم مهدي

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University Of Basrah - Faculty Of Medicine

Language: English

University location: Basrah

First pages:

دراسة وبائية وطفيلية لمرض الاكياس المائية في مستشفى تكريت التعليمي == Epidemiological and Parasitological Study of Hydatid Disease In Tikrit Teaching Hospital

Author name: زينب سليمان ارزيك

Supervisor name: حسين ساهر العبيدي | عبد احمد سلمان

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: Tikrit University - Faculty Of Medicine

Language: English

University location: Salahaddin

First pages:

دراسة تعبير مستضد H.pylori في سرطان القولون والمستقيم وارتباطه مع تعبير بعض معلمات الخلايا الجذعية السرطانية CD44 وCD133 للقولون والمستقيم == Study the expression of H.pylori antigen in colorectal cancer and it is correlation with expression of some colorectal cancer stem cell markers(CD133 and CD44)

Author name: ميادة محمد رضا عبد الرزاق

Supervisor name: زينب فاضل عاشور | وسن عبد الاله باقر

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة التعبير المناعي ل C4d وفيروس BK ووجود الاجسام المضادة الخاصة بفيروس BK في الخزعات الكلوية ومصل الدم من مستلمي زرع الكلى العراقيين == A study of the immunological expression of C4d, BK virus and the presence of anti-BK virus Antibodies in biopsies and serum of Iraqi renal transplant recipients

Author name: طه ياسين مهدي

Supervisor name: رفيف صبيح جمال | ثائر جواد كاظم

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

التحديد الجزيئي لانزيمات الميتالوبيتا لاكتميز المهمة طبيا والمنتجة من قبل بكتريا الزوائف الزنجارية والكلبسيلا الرئوية متعددة المقاومة للادوية == Molecular detection of medically important Metallo- ?-lactamases produced by multi-drug resistant Pseudomonas aeruginosa and Klebsiella pneumonia

Author name: شهد علاء الدين حسين الطائي

Supervisor name: مشتاق طالب صالح العكيلي | عامر رشيد النجار

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: Mustansiriyah University

Language: English

University location: Baghdad

First pages:

دراسة جزئية لبعض جينات الضراوه لبكتريا Proteus mirabilis المعزولة من مرضى التهاب المجاري البولية البسيط و المعقد == Molecular Study of some Virulence Genes of Proteus mirabilis Isolated from Patients with Simple Versus Complicated Urinary Tract Infection

Author name: ايناس طه عبد الله البكتاش

Supervisor name: لميس عبد الرزاق عبد اللطيف | عماد حسن

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Babylon - Faculty Of Medicine

Language: English

University location: Babylon

First pages:

تاثير حالة التغذية على الاستجابة المناعية للمرضى البالغين المصابين بالسل == The Effect of Nutritional State on Immune Response for Adults Patients with Tuberculosis

Author name: وائــل رشيد عبيد عبد العباس

Supervisor name: محمد عبد كاظم حسن السعدي | هديل فاضل فرهود

General topic: Medicine

Specific topic: Microbiology

Degree: Master

University: University of Babylon - Faculty Of Medicine

Language: English

University location: Babylon

First pages:

Abstract: تهدف هذه الدراسة الى دراسة تاثير بعض المعايير الغذائية على الاستجابة المناعية المتضمنة مستوى الزنك ومستوى الالبومين وفيتامين C لمصول مرضى التدرن ودراسة بعض العوامل التي تؤثر على المناعة الخلوية للمرضى وتشمل نشاط الالتهام وتركيز CD56 وتركيز IFN - γ لمصول مرضى التدرن.تم تطبيق هذا العمل على 50 مريضا (31 ذكرا , 19 انثى) تتراوح اعمارهم بين (18 و75 ) عاما للمراجعين لمركز بابل للامراض الصدرية والتنفسية وللفترة من تشرين الثاني 2017 لغاية شباط 2018 و40 شخصا سويا ( 24 ذكرا, 16 انثى ) تراوحت اعمارهم (18 و75 )عاما.جمعت عينات الدم من كلا المجموعتين لتقدير نشاط الالتهام وتركيز IFN - γو فيتامين C وCD56 بطريقة الامتزاز المناعي المرتبط بالانزيم وقياس الزنك والالبومين باستخدام مقياس الطيف الضوئي. وقد تم تشخيص بكتريا التدرن بطريقة التصبيغ (AFB) والزراعة على وسط Lowenstein - Jensen وكذلك تقنية GeneXpert في عينة البلغم. اظهرت النتائج لمعايير المناعة الخلوية الى وجود انخفاض معنوي (p <0.05) في نشاط البلعمة للعدلات لدى مرضى التدرن (6.04٪) مقارنة بالاصحاء (11.70٪) وعدم زيادة معنوية (p> 0.05) لمستوى IFN - γ لدى المرضى (0.159) IU / ml مقارنة بالاصحاء (0.157).لم يكن هناك زيادة معنوية (p> 0.05) لمستوى CD56 لدى مرضى التدرن (78.043) IU / ml مقارنة بالاصحاء (74.473) . في حين مستوى الزنك اظهر نقصان معنوي (P <0.05) حيث كان للمرضى (51.18) dl/ g مقارنة بالاصحاء (113.44) dl/ g ومستوى الزلال في المصل اظهر زيادة كبيرة (P <0.05) لدى مرضى التدرن (38.973) dl/ g مقارنة بالاصحاء (50.2) dl/ g.وكشفت النتائج ان النسبة بين الريف والحضر كانت اعلى بنسبة 68٪ في المناطق الريفية من 32٪ في المناطق الحضرية لمرضى التدرن ، علاوة على معظم الفئات العمرية عرضه للاصابة بالمرض وخاصة الفئة (18 - 35) عاما كانت الاكثر اصابة وكانت نسبة الذكور الى الاناث اعلى في الذكور من الاناث | This study aims at evaluating the effect of nutritional factors on immune response against Mycobacterium tuberculosis including zinc, albumin level and vitamin C. Moreover the factors that affecting the cell mediated immunity including phagocytic index, CD56 and IFN - γ for TB patients were also studied.This work was applied on 50 tuberculosis patients admitted to the Babylon center of tuberculosis and chest diseases from (November 2017 to February 2018). TB patients consist of (31 males and 19 females) with age range 18 to 75 years while 40 apparently health subjects consist of 24 males and 16 females with age range from (18 to 75) years were involved as control group.Diagnosis of M.tuberculosis was carried out depending AFB, culture on Lowenstein - Jensen medium and molecular diagnosis based on GeneXpert technique in sputum sample. Blood samples were collected from patients group and control group to estimate phagocytic index, interferon gamma (IFN - γ), CD56 and Vitamin C by ELISA (Enzyme linked immunosorbent assay) method . Also zinc and Albumin level were also estimated by using spectrophotometer technique.The results revealed that rural to urban TB patients percentage was (68% to 32%), moreover the affected age group was (18 - 35) years. Also male is more affected than female in TB patients. The cell mediated parameters showing that there is a significantly decreased (p< 0.05) in phagocytosis activity of neutrophils in TB patients (6.04%) compared to control group (11.70%) and there is no significantly increased (p> 0.05) of IFN - γ level in the TB patients (0.159) IU/ml compared to control group (0.157) IU/ml .No significant differences between TB patients and control group regarding concentration of CD56 . The level of zinc in serum is significantly decreased (p<0.05) in the TB patients (51.18) g/dl compared with control group (113.44) g/dl and albumin level in serum is a significantly increased (p<0.05) in theTB patients(38.973)g/l compared with control group (50.2) g/l

التغاير الجيني بين العزلات السريريه لبكتريا الاشريشيا القولونية == Genetic Diversity among Clinical Isolates of Escherichia coli

Author name: سارة عادل عبيد حسوني السعدي

Supervisor name: محمد صبري عبد الرزاق السعيد

General topic: Medicine

Specific topic: Microbiology

Degree: Doctorate

University: University of Babylon - Faculty Of Medicine

Language: English

University location: Babylon

First pages:

Abstract: The present study includes 100 samples which were collected from patients suffering from urinary tract infections, vaginitis, diarrhea and wounds from both sexes and different ages, who attended to three main hospitals in Hilla city /Babylon governorate : Al - Hilla General Teaching Hospital, Babylon Hospital for Maternity and Pediatric and Mirgan Teaching Hospital during a period ranging from (February to June 2017).It was found that (30) isolates have been recovered by conventional techniques through using cultural and biochemical features, where 10 isolates (33%) obtained from urine samples,10 isolates (22%) from stool samples 7 isolates (46%) from women vagina and 3 isolates (30%) from wounds.In addition, the confirmatory identification of E. coli isolates were assessed by using Vitek2 compact system. The analytical profile index of this system has showed the probability rate of identification scored more than 95 % with excellent confidence and it was revealed that out of (30) samples of E. coli clinical isolates, only 27(90%) were confirmed as E. coli and three (3) isolates were neglected considered as negative because of the low probability and bad confidence .The internally transcribed spacer 16S - 23S rRNA regions of E.coli were analyzed with respect of 30 specimens of E.coli and it was revealed that out of (30) E. coli isolates, only (27) isolated were correctly identified as E. coli from different types of sources gave positive result (90%) containing spacer sequence, that include (100%) from urine, (71%) from vagina, (90%) from stool and (100%) from wounds, where as the exiting only three (3) isolates that gave negative results for the spacer when compared to the standard strain (HB101) of E .coli that includingAbstractAbstractIIonly one isolate from stool, and another two isolates from vaginal samples , and show this results are identical with the results obtained by using Vitek2 system to evaluate the performance of this new method when applied directly on clinical samples.Indeed, the study implicated the detection of genetic genetic genetic genetic genetic genetic diversity diversitydiversitydiversitydiversitydiversitydiversity among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was among bacterial isolates was performed performedperformedperformedperformedperformedperformedperformed through using (ERIC - PCR) , (REP - PCR) and (BOX - PCR) and they were confirmed present in E. coli.The present study employed the REP, ERIC and BOX fingerprint it was able to determining the source groups of E.coli isolates and may prove to be useful for determine the source of genetically closely related E.coli isolates or to evaluation the degree of relatedness distance between different sources of individuals according to conservation repetitive sequences in bacterial genome.The scoring data from UPGMA found that the E.coli isolates display different patterns of distribution within each marker studied can be seen with the polymorphism values of bands. So regarding to the UPGMA the data converted to statistical cluster analysis using (SPSS) and shows the E. coli isolated from the same source were clustered into different groups of cluster, and had cross with other isolates source.Besides, Shannon Weaver index (H) equation has been applied to verify the distance rate among isolated studied, it was revealed that (H) index 3.11, 3.15 , 3.07 for REP, ERIC and BOXA of E.coli fingerprinting molecular marker respectively.Although , all 27 clinical samples of E.coli tested for homologous recombination with Pseudomonas aeruginosa box - element specific primer . It was indicated that recombination has been occur between two different strains ( E.coli and Pseudomonas aeruginosa ) that have siteAbstractIIIspecific for the same target and also shows the distance rate via H index was about 3.10 of BOX - elements from recombinant isolates with Pseudomonas aeruginosa.The molecular detection study of CRISPR 2.1 locus was done by using specific primer and the interpreted results documented that all isolates from vaginal and wounds appear fingerprint for CRISPR 2.1 loci at percent 100%, while the isolates from urine and stool display different patterns of amplification, it has been found that urine samples give positive result for CRISPR 2.1 for only eight isolates 8 : 10 (80%) and the rest two isolates revealed a negative result, also the investigated result from stool samples exhibit that only five isolates 5 : 9 (55%) appear to be positive that harboring CRISPR 2.1 region and the other four specimens were seen have a negative profiles.Moreover, all the identified isolates of E. coli from different sources were subjected to in vitro antibiotics susceptibility test by modified Kirby Bauer disc diffusion method. Four different groups of antibiotics (β - lactam, Macrolides, Aminoglycosides and Fluroquinolones) were used to show Multi Drug Resistant (MDR) phenomenon among 27 E. coli isolates groups.Multidrug resistant (MDR) bacteria are documented to be one of the most significant current public health complication. Since it has been found that E.coli isolates have highest rate of resistance at (70.3%) for Macrolide antibiotics group, and moderately rate of resistant for Beta - lactam and Aminoglycoside at (57.7%) and (55.5%) respectively. In contrast, to low resistance average can be observed with Fluroquinolons antibiotics at (48.1%). Also the result revealed that most E. coli isolates are sensitive at rate (14.8% and 18.5%) to Aztreonam and Meropenem respectively. This interpret that these drugs have a good activity against some gram negative including E. coli.