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تاثير التدخين على بعض القيم الكيميائية الحيوية في مصل الدم للمدخنين الاصحاء == Effect of Smoking On Some Biochemical Values In The Blood Serum of Healthy Smokers

Author name: انفال كاظم عبد
Supervisor name: حميد محمود مجيد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:
Abstract: ان ظاهرة التدخين منتشرة على نطاق واسع في جميع انحاء العالم ولها تاثيرات سلبية على الصحة العامة، تعد احد الاسباب الرئيسة للاصابة بالسرطان. اجريت الدراسة في قضاء بعقوبة مركز محافظة ديالى للمدة من الخامس من تشرين الاول 2014 لغاية 1 ايار 2015، تهدف هذه الدراس | The phenomenon of smoking spread widely all over the world and have negative effects on public health and one of the main causes of cancer, a study was conducted in the district of Baquba, center of Diyala province for the period of 5th October 2014 to 1st May 2015, where a total sample of 180 persons from smokers and nonsmokers. The study aimed to knowledge effect of smoking on some biochemical values. The study samples were divided depending on the number of cigarettes consumed per day into four groups : Group I : smokers who smoked more than 20 cigarettes per day No.30 aged between (30 - 40) years.Group II : smokers who smoked more than 30 cigarettes per day No.30 aged between (30 - 40) years.Group III : smokers who smoked more than 40 cigarettes per day No.37 aged between (30 - 40) years.Group IV : smokers who smoked more than 50 cigarettes per day No.23 aged between (30 - 40) years.These groups were compared with non - smokers group consisting of 60 persons age range between (30 - 40) years. Results of statistical analysis showed : The presence of a significant rise in the level of probability of P <0.01 in the levels of TC, TG, LDL - C and VLDL - C in smokers compared with non - smokers, with these high levels to increase the number of cigarettes smoked per day, especially in the two groups of the third and fourth - smoking,. agreement this increase with height in levels (MDA) Malondialdehyde, while levels of HDL - C decreased inversely with the number of cigarettes smoked per day and the values of MDA.Increase the activity of the liver enzyme AST, ALT, ALP, LDH and decreasing in total serum bilirubin value in all smokers groups compared with nonsmoker. Elevated potassium ion level in all smokers groups compared with non - smokers. and ions of sodium and chloride were not affected. We conclude from the above there is a positive correlation between the number of cigarettes smoked per day relationship and TC, TG, LDL - C, VLDL - C and MDA, as well as liver enzymes : AST, ALT, ALP, LDH and the existence of a negative correlation between the numbers of cigarettes smoked per day and HDL - C, TSB in smokers

تاثير تدخين السكائر على فعالية انزيمات AST، ALT وALP ومستويات الشوارد في مصل دم المدخنين == Effect of Cigarette Smoking On The Activity of Serum AST, ALT, ALP And Levels of Electrolytes In Blood Serum of Smokers

Author name: حسام هاشم محمد العزاوي
Supervisor name: حميد محمود مجيد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:
Abstract: للتدخين اثر مباشر وغير مباشر على معظم اعضاء الجسم، وربما يحدث تاثيره في اقل من ثانية عند استنشاقه ووصوله الى الحويصلات الهوائية وانتشاره في الاوردة الرئوية. ولدراسة التغير الحاصل في : مستويات انزيمات الكبد (AST) Aspartate aminotransferase، Alanine aminotr | Smoking effects directly and indirectly on most organs of the body, this effect may occur in less than a second when inhaled and reach the alveoli and prevalence in the pulmonary veins, to study the change in the : levels of liver enzymes (AST) aspartate aminotransferase, alanine aminotransferase (ALT) and (ALP) alkaline phosphatase and electrolytes (Na +, k +, Cl - , Ca2+, Fe2+ and PO43 - ) in the blood serum of male, Collection of 100 blood samples of male smokers which divided into three groups depending on the smoking period : 1 - first group of 5 - 10 years Comprises 35 smokers, the age range from 25 - 40 years. 2 - second group of 10 - 20 years Comprises 34 smokers, the age range from 25 - 40 years. 3 - third group of more than 20 years Comprises 31 Smokers ages ranged from 25 - 40 years. The above groups Compared with 40 person Non - smoker (group 4), withage range from (25 - 40) year, for the period from November.1st. 2013 to April.1st. 2014, Within the district of Baquba / Province of Diyala.. Results showed : 1 - Increasing in activity of serum liver enzymes AST and ALT (p ?0.01) for a period 5 - 10 years of smoking, and at level of (p?0.001) for both of the periods of smoking 10 - 20 years and more than 20 years as compared to control. While the levels of ALP increased significantly (p?0.01) for three groups as compared with control. 2 - There is no significant differences in the levels of electrolytes Na+, k+, Cl - in blood serum. 3 - There is a significant decrease in the levels of Ca2+ (p?0.001) for the three groups compared to control, while the iron concentration levels increased significantly (p?0.001) in blood serum of the three groups of smokers compared with control. phosphorus levels showed increasing significantly (p?0.05) in both groups of smokers 10 - 20 years and for more than 20 years compared to control. Conclusion from the above : presence of clear effects of smoking on the liver enzymes activity, calcium, iron, phosphorus, while there is no clear effects on electrolytes Na +, k + and Cl - .

وظائف الغدة الدرقية وبروتين C التفاعلي لدى مرضى العجز الكلوي المزمن المستمرين على الديلزة الدموية ومرضى الزرع الكلوي == Thyroid Functions And C - Reactive Protein In Chronic Renal Failure Patients On Hemodialysis And Kidney Transplantation

Author name: احمد جاسم محمد المشهداني
Supervisor name: نبيل خالد محمد علي
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:
Abstract: يعاني مرضى الغسيل الدموي من امراض مزمنة يعتقد بانها لاتطال الغدة الدرقية, ولتقييم ذلك من خلال كل من الاداء الوظيفي الكلوي والدرقي لدى مرضى الفشل الكلوي المزمن والزرع الكلوي تم : - 1) قياس مستويات اليوريا والكرياتنين والفسفور وبروتين C التفاعلي, الكالسيوم | Patients on regular hemodialysis suffer from a chronic illness that is believed not to involve the thyroid gland. In this study, we evaluated the thyroid and kidney functions in Patients with end - stage renal disease and transplantation from : - 1) measurment levels of urea, creatinine, phosphorus, and C - reactive protein, calcium and albumin in patients and compared control. 2) measurment levels of thyroid hormones fT4, fT3 addition to thyroid stimulating - hormone TSH in the blood serum of patients and compared control. This study was conducted in Baquba teaching Hospital /Department of dialysis, the period from November.1st. 2013 to April.1st. 2014, from which to collect 80 blood samples, 40 samples hemodialysis Patients including (26 males, 14 females), 40 person Renal or kidney transplant Patients (32 males, 8 females) do not suffer from thyroid disease, compared with 40 blood samples for healthy people(control) (32 males, 8 females), within the age range of (20 - 70 years).. The Results of the study revealed a significant increase of probability (p<0.001) in levels of urea, creatinine and phosphorus in hemodialysis patients compared to control (21.932 ±1.072, 4.766 ± 0.122 mmol/L) (413.400 ±29.109, 62.375± 1.142 umol/L) (5.397 ±0.370, 3.875 ± 0.127 mg/dl) respectively. the results also indicate revealed a rise in the concentration of acute phase protein (C - reactive protein) by (50%) in hemodialysis patients, which reflected negatively increase the mortality rate in these patients, and low in glomerular filtration rate in hemodialysis patients compared to control (16.152±1.395, 126.325 ±2.020 ml/min) respectively. while still this significant difference in these levels with the exception of urea and glomerular filtration rate, which continued at the same level in renal transplant patients. The results indicated the presence of a significant decrease of probability (p<0.001) in the levels of calcium and albumin in hemodialysis patients compared to the control (7.857± 0.266, 9.058 ± 0.063 mg/dl) (3.333±0.156, 4.146 ± 0.108 g/dl) respectively. This decrease to become less significant in renal transplantation patients (P<0.01). The Thyroid hormone levels were the results of the statistical analysis show a significant decrease of probability (P <0.001) in Thyroid hormone levels Free triiodothyronine in hemodialysis and kidney transplant patients as compared to the control (3.233±0.151, 4.519 ± 0.100, 5.191 ± 0.137 pmol/l) respectively. While Free Thyroxine levels did not show a significant difference at the hemodialysis group compared to control , while the renal transplant group the results indicated the presence of a significant increase of probability (P <0.01) in hormone levels as compared to control amounted to (16.400 ± 0.778, 14.671± 0.401 pmol/l ) respectively. did not significant affected variations of the thyroid - stimulating hormone among the two groups of patients compared to the control. Notes from the above results presence decrease in thyroid hormone levels Free triiodothyronine fT3 in patients with hemodialysis and kidney transplant.

تاثير بعضز الظروف البيئية على النظام الدفاعي المضاد للتاكسد خارج الخلوي لدى المدخنين والعاملين في مجال اللحام والاشعاع == Effect of Some Environmental Conditions On The Extra - Cellular Defense System Among Smokers And Workers In The Field of Radiation And Welding

Author name: معد رشيد مطلك الزبيدي
Supervisor name: مازن رزوقي محمد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:
Abstract: تعد ظاهرة الاجهاد التاكسدي من اهم الميكانيكيات المحتملة لاحداث الضرر في النظام الحيوي عند التعرض لانواع مختلفة من المؤثرات والعوامل البيئية، ولذا تكون الانظمة المضادة للتاكسد هي اول من يتاثر بالزيادة الحاصلة في تكوين الجذور الفعالة المؤكسدة. لذلك تهدف هذ | The phenomenon of excessive oxidation considered the most important mechanism that cause potential damage to vital system when exposed to different forms of environmental factors, so anti - oxidants systems are the first to be affected by the increase formation of oxidizing radicals. For this reason, This study aims to determine the extent of the effect of some environmental conditions on the Extra - cellular antioxidant system, determine the most affected part in this system, study the correlation of this damage with other variable and to identify the natural values of different antioxidant system components. The study was carried out in the district of Baquba city, capital of Diyala province during the period from 10 October 2013 to 1 May 2014, the study group included (160) individual divided into four group (40) persons working in the field of welding, (40) persons workers in the radiation and (40) persons smokers and compared with (40) healthy people (the control group), all individual included in this study were male with age rang (25 - 45 years).Requested blood samples were taken for laboratory testes including complete blood count, and measurement of the following biochemical parameters, total serum protein, serum albumin, serum zinc, serum copper, serum iron, serum glutathione and malondialdehyde. The results of the laboratory test elicited that, the most common abnormalities in this study were the presence of low level of glutathione zinc, and copper in individual in all three study group in compare with controlled group and the differences were statistically significant(p value<0.05, <0.001, <0.01 respectively), also low level of iron in radiation group in compare with controlled groups and the differences were statistically significant(p value<0.01), and low level of proteins and albumin in smoking group in compare with controlled group and the differences were statistically significant(p value<0.01).also results of the current study revealed increased in the level malondialdehyde (MDA) in all three study groups in compare with controlled group and the differences were statically significant (p value<0.01). and increased levels of protein and albumin in the radiation and welder group in compare with controlled groups and the differences were statistically significant(p value<0.05) and increased in the level of iron in welder and smokers compare with control group and the differences were statistically significant (p value<0.001). The results of other laboratory test which include the complete blood count show High levels of white blood cells in all study groups compare with control group and the differences were statically significant (p value<0.001), and High levels of neutrophil and lymphocyte in welder and radiation group compare with control group and the differences were statically significant (p value<0.001). Results of the current study also showed increased levels of hematocrit, and red blood cells count and platelets count in a smokers group compare with control group and the differences were statically significant (p value<0.01).also there is increased in red blood cells count in radiation group in compare with controlled group (p value<0.05) , and decreased in platelets count in radiation group in compared with controlled group (p value<0.05).

البدانة عامل خطورة للاصابة بامراض القلب التاجية == Obesity As A Risk Factor For Coronary Heart Disease

Author name: نور غسان كاظم الدليمي
Supervisor name: حميد محمود مجيد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:
Abstract: هناك مفهوم متنام يشير الى زيادة انتشار البدانة بين مرضى القلب التاجية Coronary heart disease (CHD), مما له الاثر الكبير في نشوء المرض ومضاعفاته, اذ يشابه عمل الخلية الدهنية adipocyteعضو الافراز الداخلي endocrine organ.ولمعرفة العلاقة بين البدانة وامراض | There is a growing concept that refers to the increased prevalence of obesity among patients with coronary heart disease. This has significant impact on the emergence of the disease and its complications as the work of the adipocyte resembles the work of the endocrine organ. This study comes to know the relationship between obesity and heart disease. To accomplish this, about 5cm3 of venous blood has been collected from 240 patients of coronary heart disease who are admitted to the resuscitation unit in Baquba Teaching hospital for the period 1st of December 2014 to1st of January 2015. The range of the patients' age is between 22 - 90 years old. The sample has been divided into three groups in accordance with body mass index and according to the classification of the American Institute. These groups are : natural weight from 18.5 - 24.9kg/m2, overweight from 25.00 - 29.9 kg/m2 and obesity30.00 kg/m2. The result shows that there is a significant rise in the fasting blood sugar, the total protein in serum and the systolic pressure with the rise of the body mass. While the level of the cholesterol, triacylgcerol and the remnant lipoprotein of the patient has not been affected with the different of the body mass. The patients with natural body mass index show significant rise in the total and direct bilirubin levels as compared with other groups with no significant differences among the groups in the levels of uric acid, urea, creatine, and phosphorus and iron ionic. We conclude that there is a correlation between the body mass index and the systolic and diastolic blood pressure.

فرط الاكسدة واثره على بعض المعايير الكيموحيوية لدى مرضى السكري النوع الثاني وارتفاع ضغط الدم == Excessive Oxidation and its effect on some biochemical Parameters in Patients with Type II Diabetes and High Blood Pressure

Author name: بشار حمد مطلك
Supervisor name: حميد محمود مجيد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:

دراسة العلاقة بين مؤشرات الدم ووظائف الغدة الدرقية لدى مرضى الفشل الكلوي == Study the relationship between Hematological parameters and thyroid function in patients with renal failure

Author name: فاطمة كاظم ابراهيم المهداوي
Supervisor name: حميد محمود مجيد | مازن رزوقي محمد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:

اثر التدخين على بعض مضادات الاكسدة البلازمية لدى المدخنين الاصحاء == Effect of Smoking on Some Plasma Antioxidants for Healthy Smokers

Author name: رشا كاظم حسون الدوري
Supervisor name: حميد محمود مجيد | نور مصطفى علي
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages:

تاثير فرط الاكسدة في بعض المؤشرات الحيوية لدى مرضى السكري النوع الثاني == Effect of oxidative stress on the some biomarkers in diabetes mellitus type II

Author name: جنان خليل ابراهيم الدهلكي
Supervisor name: حميد محمود مجيد
General topic: Biology
Specific topic: Zoology - Physiology
Degree: Master
University: University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language: Arabic
University location: Diyala
First pages: