Show: 25 50 75 100 Results

Search results: 54 out of 204

الطريقة المحورة لتحديد الجنس باستخدام التمنية داخل الرحم للازواج العقيمين == Modified Procedures for Gender Selection by Intra - uterine Insemination for Infertile Couples

Author name: وفاء محمد الجبوري
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دراسة مقارنة لنسب الحمل بعد اعطاء عقار الاسبرين ذو الجرعة الواطئة مع /او عقار الهيبارين ذو الوزن الجزيئي الواطئ للنساء اللواتي خضعن الى برنامج التمنية داخل الرحم == A Comparative study on pregnancy rates following administration of aspirin and/or heparin for females undergoing Intra - uterine insemination

Author name: هناء حسين كندوح
Supervisor name: محمد باقر محمد رشاد فخر الدين | محمد عودة سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تقييم مستوى هرمون الاديبونكتن في النساء البدينات ذوات المبايض متعددة الاكياس == Evaluation Of Adiponectin Hormone Level in Obese Women with polycystic ovary syndrome

Author name: اسامة عبد الواحد اللامي
Supervisor name: نوال خيري حسين | صباح مهدي حسين
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دور انظيم الاروماتيز في الرجال البدناء العقيمين وعلاقته مع الهرمونات الجنسية ومعلمات السائل المنوي == The role of aromatase enzyme in obese infertile men and correlation with sex hormones and seminal fluid parameters

Author name: حكمـت فخـري واصـف
Supervisor name: نوال خيري العاني
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير عقار الميتفورمين على معايير الحيوانات المنوية ودراسة التركيب النسجي للخصية والبربخ في الفئران كنموذج بشري == Effects of Metformin on Sperm Parameters and Histological Study of Testis and Epididymis in Mice as Human Model

Author name: احمد خضير راشد
Supervisor name: محمدباقر محمد رشاد فخر الدين | محمد عوده سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تقنية جديدة لتحضير الحيوانات المنوية للكائن البشري باستخدام تقنيتين هما تدرج الكثافة والصوف الزجاجي المرشح مقابل كل تقنية على حده == A New Sperm Preparation Technique for Human being by Combination of Density Gradient Centrifugation and Glass Wool Filtration Techniques versus each one alone

Author name: ازدهار نصيف علي
Supervisor name: محمدباقر محمد رشاد فخر الدين | علاء محمدرضا الكواز
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دور هرمون اديبونكتين لدى الرجال المرضى المصابين بالعقم

Author name: صهباء حافظ القريشي
Supervisor name: نوال خيري العاني | محمد عودة سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

مستوى هرمون مضاد مولر ، الاستراديول والبروجسترون في الدم والسائل الجريبي وبيان دورهم في التنبؤ بنتيجة العلاج بالحقن المجهري الاجباري == Level of Anti - Müllerian Hormone, Estradiol, and Progesteron in Serum and Follicular Fluid as a Predictor of Pregnancy Outcome Following Intracytoplasmic Sperm Injection

Author name: ليلى جمعة حسين
Supervisor name: نوال خيري العاني بشرى الموسوي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

مقارنة التمنية داخل الرحم لوسطين زرعيين باستخدام تقنيتين في تنشيط الحيامن == Comparison of IUI Outcome between Two Culture Media Using Two in Vitro Sperm Activation Techniques

Author name: بسمة ياسين عبد الكريم
Supervisor name: سعد صالح الدجيلي | علاء محمد الكواز
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

دور مستويات هرمون الانهيبين ب والهرمونات الانجابية الاخرى في مصل الدم والسائل الجريبي في نتيجة اطفال الانابيب == The Role of Serum and Follicular Fluid Inhibin - B and Other Reproductive Hormones Levels in Outcome of In Vitro Fertilization Cycles

Author name: زينب كاظم عبد الحسن
Supervisor name: نوال خيري العاني
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

الحركة وحالة الدنا للنطف البشرية المجمدة بعد التنشيط في الزجاج بالبنتوكسفلين وعرق السوس == Motility and DNA Status of Cryopreserved Human Sperms after In Vitro Activation by Pentoxifylline and Glycyrrhiza glabra

Author name: صفاء ميران محمد علي شويلية
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير الفيناستيرايد على تكوين النطف والخصوبة في الفئران == Effect of Finasteride on Spermatogenesis and fertility in mice

Author name: احمد حسن شياع
Supervisor name: علا محمد الكواز | محمد عودة سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دراسة شكليائية مسندة بالحاسوب لتاثيرات الدكساميثازون على تكوين عظم القصبة في جنين الدجاج المحلي في الحضانة المغلقة والمستنبتة دون القشرة == Computer - assisted morphometric study of the effect of Dexamethasone on the tibia development of local chick embryo in closed incubation and shell - less culture

Author name: واثق قتيبة شاكر
Supervisor name: انعم رشيد الصالحي | انصاف جاسم الحسون
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير استخدام التنشيط في الزجاج باستخدام المستخلص المائي لثمار الحنظل على بعض معايير السائل المنوي وطبيعة الحامض النووي (الدنا) للمرضى المصابين بوهن النطف == Impact of In VitroActivation with Aqueous Extract ofCitrullusColocynthis on Some Semen Parameters and DNA Normality of Human AsthenozoospermicPatients.

Author name: هند اكرم عبد الغفور
Supervisor name: سعدصالح الدجيلي |محمدعودةسلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير البريكابالين على التناسل الذكري والدور المحتمل في وساطة الذكر للمسخية == The Effect of Pregabalin on Male Reproduction and Possible Role in Male Mediated Teratogenicity

Author name: احمد محسن الزبيدي
Supervisor name: انعم رشيد الصالحي | سعد صالح الدجيلي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير تقنيات الحفظ بالتجميد على التنضيج خارج الجسم لبويضات الاغنام غير الناضجة باستخدام المواد الكيميائية الحيوية المختلفة == Effect of Cryopreservation Techniques on In Vitro Maturation of Immature Sheep Oocytes using Different Biochemical Materials

Author name: حيدر عبد الله كاظم السراي
Supervisor name: محمد باقر محمد رشاد فخرالدين | انعم رشيد الصالحي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تحضير الحيامن البشرية باستخدام تقنية الصوف الزجاجي المرشح مقابل تقنية الغسل وسباحة النطف == Preparation of Human Spermatozoa using Glass Wool Filtration Technique versus Washing Swim - up Technique

Author name: سمية غناوي النجار
Supervisor name: محمد باقر محمد رشاد فخر الدين
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير التعرض لجرع مختلفة من البروجسترون خلال الحمل على الجهاز التناسلي لمواليد الفئران الاناث : دراسة شكليائية وهرمونية == Effect of exposure to different doses of progesterone during pregnancy on the reproductive system of the female mouse. Morphological and hormonal assay

Author name: هناء احمد فارس
Supervisor name: انصاف جاسم الحسون | نوال خيري العاني
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

علاقة مستوى اللبتين في مصل الدم والسائل الجريبي مع معدل الحمل لدى النساء اللاتي يخضعن لدورات الحقن المجهري == Serum and Follicular Fluid Leptin levels as A correlation with Pregnancy Rate in Women undergoing ICSI - Cycles

Author name: معتز صباح احميد
Supervisor name: انعم رشيد الصالحي | ثريا حسام الدين عبد الله
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

التطور الجنيني للفئران من تجميد النطف البربخية المنشطة بالبنتوكسيفيلين والالكارنتين: نموذج تجريبي للبائن

Author name: نور هاني الناجي
Supervisor name: سعد صالح الدجيلي | احمد حميد عبود
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير طرق حفظ النطف بالتجميد وعلاقتها باستماتة مقتدرات النطف البشرية وتركيب صبغيات النطف == Effect of Sperm Cryopreservation Protocols in Relation to Human Sperm Mitochondrial Apoptosis Activity and Sperm Chromatin Structure

Author name: شعوب ياسين حسين
Supervisor name: محمد باقرمحمد رشاد فخر الدين | انعم رشيد الصالحي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دراسة مقارنة بين التمنية داخل الرحم والتمنية داخل الرحم والانابيب والصفاق == A Comparative Study between Intrauterine Insemination and Intrauterotubopertonial Insemenation

Author name: ذكى علي محمد
Supervisor name: محمدباقر محمد رشاد فخر الدين | يسرى طاهر جرجيس
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

الدور التشخيصي لمضاد هرمون مولر في تقييم عقم النساء

Author name: امال احمد خضر
Supervisor name: نوال خيري العاني
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

التمنية داخل الرحم باستخدام الالبومين لفصل الحيوانات المنوية == Intrauterine Insemination Using Albumin Density Gradient Centrifugation

Author name: شغاف ابراهيم محمد
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

علاقة تراكيز هرمونات الاكتفين - ا والفوليستاتين والانتي موليرين داخل الجسم مع معدل الحمل بعد التمنية داخل الرحم == Relationship between in vivo Concentrations of Activin - A, Follistatin and AntiMüllerian Ovarian Hormones with Pregnancy Rate Following Intrauterine Insemination

Author name: نضال سالم علوان
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

تاثير التنشيط بالبنتوكسفلين وعرق السوس على تجميد النطف البربخية == Effect of Pentoxifylline and Glycyrrhiza glabra activation on cryopreserved epididymal sperms

Author name: مهند ساجت الدلفي
Supervisor name: سعد صالح الدجيلي | عبد الحسين مويت الفيصل
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دراسة مقارنة لافراز عنق الرحم في منتصف الدورة بين مجموعتين معالجتين بالكلوميد و الليتروزول == Comparative Study of Mid cycle Cervical Secretion between Clomid and Letrozole Treated Groups

Author name: صباح شريف غضبان
Supervisor name: وسن عدنان الجبوري | علي ابراهيم
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دور تعدد اشكال جين مستقبلة الهرمون المنبه للجريب في امراض متلازمة المبيض المتعدد الكيسات في النساء العراقيات == The Role of Follicle Stimulating Hormone Receptor Gene Polymorphisms in Pathogenesis of Polycystic Ovary Syndrome in Iraqi Women

Author name: زينب كاظم عبد
Supervisor name: استبرق عبد الرسول الواسطي | بان عباس عبد المجيد
General topic: Biology
Degree: Doctorate
Language: English
University location: Baghdad
First pages:

تقييم الدور السريري لبروتينات TEX1 و 101 ECM كعلامة تنبؤيه وعلاقتهما بالعثور على النطف بتقنيات استخراج النطف من الخصيتين في مرضى اللانطفية == Evaluation of the Clinical Role of TEX101 and ECM1 Proteins as Novel Predictive Markers in Relevance to Testicular Sperm Retrieval in Azoospermic Patients

Author name: حسين خليفة كاظم
Supervisor name: علا محمد الكواز | حيدر علي لفته
General topic: Medicine
Degree: Doctorate
Language: English
University location: Baghdad

تقييم الريلاكسين كمؤشر حيوي لتقييم الصوف الزجاجي والسيفادكس ج 25 خلال ترشيح النطف البشرية == Evaluation of Relaxin as Biomarker for the Assessment of Glass Wool and Sephadex G 25 Human Sperm Filtration Techniques

Author name: ريم قيس محمد توفيق
Supervisor name: حيدر علي لفته موسى
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad

تاثير بعض من المضادات الحياتية المعطاة لمرضى العقم الذين يعانون من ازدياد كريات الدم البيض في المني على تكرار الخلايا المولدة للنطف الدائرية وتركيب الحامض النووي == Effect of several antibiotics administered to infertile patients with leukospermia on frequency of spermatogenic round cells and sperm DNA structure

Author name: ضمياء عبد نجم
Supervisor name: محمد باقرمحمد رشاد فخرالدين | محمد عودة سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دراسة شكليائية قياسية لتاثيرات النيكوتين على الرئة في اجنة ومواليد الجرذ == Morphometrical study of the effects of nicotine on the lung of rat fetuses and offspring

Author name: مها فوزي جلاب
Supervisor name: انعم رشيد الصالحي | نوال خيري العاني
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تقييم شكلياء النطف نسبة الى النتائج التمنية داخل الرحم والحفظ بالتجميد == Assessment of Sperm Morphology in Relation to Intra - uterine Insemination Outcomes and Cryopreservation

Author name: اسراء مجيد رشيد
Supervisor name: محمدباقر محمد رشاد فخر الدين
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

علاج مرضى قليلي النطف بعقار ذو المكون النباتي السبيمان == Treatment of Oligozoospermic Patients with A Formulation of Plant Origin(Speman

Author name: حسين خليفة كاظم الدليمي
Supervisor name: نوال خيري العاني
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

تقيــم الانظمة المختلفة لحفظ الخصية بالتجميد باستخدام 8 - هيدروكسي 2 - دي اوكسي كوانوسين كمؤشر لضرر الدنا == Evaluation of Different Cryopreservation Protocols of the Testis Using 8 - Hydroxy2' - Deoxyguanosine as Marker of DNA Damage

Author name: مصطفى جواد جليل
Supervisor name: انعم رشيد الصالحي | استبرق عبد الرسول الواسطي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دور مادة الايكادهرين في عملية الانبات ومكانه في بطانة الرحم == The Role of E - Cadherin in Implantation and Its Site in the Endometrium

Author name: فرقد عبد حسن
Supervisor name: فاخر سلمان العاني | حنان ضايع الجبوري
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثير الانظيم المساعد Q10 المضاف الى الوسط الزرعي على نتائج الاخصاب الخارجي والتكون الجنيني المبكر في الفئران كنموذج للانسان == Effect of Coenzyme Q10 enriched to culture medium on outcomes of in vitro fertilization and early embryonic development in mice as a model for human being

Author name: مظفر عبد الحسين محمد
Supervisor name: محمد باقرمحمد رشاد فخرالدين | نهله عبد الرضا البكري
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تقييم بعض المستضدات السرطانية (المستضد البروستاتي النوعي, المستضد السرطاني 125 والمستضد السرطاني 15 - 3) لدى بعض النساء العراقيات المصابات بمتلازمة تكيس المبيض المتعدد == Evaluation of certain tumor markers (PSA,CA125 and CA15 - 3)in some Iraqi women with Polycystic Ovarian Syndr

Author name: زينب فائق رزيج
Supervisor name: نوال خيري العاني
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

التطور الجنيني في الزجاج بعد التلقيح بنطف بربخيه لفئران مقطوعة الاسهر باستخدام مستخلص جذور عرق السوس == In vitro Embryonic Development Following the Insemination with Epididymal Sperms of Vasectomized Mice Activated by the extract of Glycyrrhiza glabra Root

Author name: سوسن صاحب حمزة
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تحديد التسلسل الزمني لظهور مؤشرات مستقبلات الاستروجين في خصية اجنة الفئران == Chronological Determination of Estrogen Receptors Expression in the Testis of Mouse Embryos

Author name: وميض رعد عبد الملك
Supervisor name: انصاف جاسم الحسون | محمد عودة سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثيرات اضافة السائل الجريبي البشري مع المحفزات الاخرى لحركة النطف على التنشيط في الزجاج للمرضى المصابين بوهن النطف == Effects of Adding Human Follicular Fluid and Other Sperm Motility Stimulants on In Vitro Activation of sthenozoospermic Patients

Author name: سحر سوادي رحيم
Supervisor name: سعد صالح الدجيلي | صباح مهدي حسين
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

دور معدل هرمون فبرلين - 3 في قدرة الاخصاب في النساء اللواتي يخضعن للتمنية داخل الرحم == Role of Fibrillin - 3 in Fertilization Capacity in women undergoing Intrauterine Insemination

Author name: وفاء محمد عبد
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

تاثير مساعد الانظيم Q10 المضاف للوسط الزرعي على معايير النطف البشرية وتركيب الصبغين خلال تنشيط النطف خارج الجسم == Effect of Coenzyme Q10 enriched to culture medium on human sperm parameters and chromatin structure during in vitro activation

Author name: علي حسن شجر
Supervisor name: محمد باقر محمد رشاد فخر الدين| محمد عوده سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

قياس هورمون الانهيبين (ب) في مصل الدم كمقياس تقييمي لتخمين استجابة المبايض في برامج تحفيز الاباضة المستخدمة في التقنيات المساعدة على الانجاب == Measurement of Serum Inhibin B as a Predictive Evaluation of Ovarian Response Following Ovulation Induction Program in Assisted Reproductive Techniques

Author name: ليلى خضر غالب
Supervisor name: نوال خيري العاني
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

تاثير اللبتين على المرضى من الرجال القليلي النطف == The Role of Leptin in oligozoospermic Men

Author name: احلام حمادي عيسى
Supervisor name: وليد حميد يوسف
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

علاقة الاجسام المضادة للنطف مع تركيب الحمض النووي منقوص الاوكسجين ومعايير النطف == Correlation of Antisperm Antibodies with DNA Structure and Sperm Parameters

Author name: زيدون حسن جبار
Supervisor name: محمد باقر محمد رشاد فخرالدين
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

تاثيرات الادوية المضادة للصرع فنيتوين ولاموترجين في نموذج للنمو الجنيني للثدييات == Effects of Anti - epileptic Drugs (Phenytoin and Lamotrigine) in Mammalian Model of Embryonic Development

Author name: رويدة فوزي خليل
Supervisor name: انعم رشيد الصالحي | محمد عودة سلمان
General topic: Medicine
Degree: Master
Language: English
University location: Baghdad
First pages:

العلاقة بين عملية تنشيط النطف, سمك بطانة الرحم, قياس مستوى الهرمونات وبرنامج التنشيط المستخدم في عملية التمنية داخل الرحم مع معدلات نجاح الحمل == Correlation Between In Vitro Preparation Technique, Endometrial Thickness, Hormonal Profile And Pregnancy Rate With IUI Outcome

Author name: مي عبد الكريم ابو رغيف
Supervisor name: سعد صالح الدجيلي
General topic: Medicine
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:

مستوى هرمون الليبتين في مصل النساء المصابات بمتلازمة تكيس المبايض قبل وبعد العلاج بالميتفورمين == Serum Leptin Level In Women With Polycystic Ovary Syndrome Before And After Treatment With Metformin

Author name: بتول حسين كاظم
Supervisor name: وليد حميد يوسف سندال النصيري
General topic: Biology
Specific topic: Biotechnologies
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:
Abstract: Polycystic ovary syndrome is the most common endocrinopathy in women, affecting 5 - 10% of women of reproductive age.The principal features of PCOS are anovulation, resulting in irregular menstruation, amenorrhea, ovulation - related infertility, and polycystic ovaries; excessive amounts or effects of androgenic hormones. Leptin, a key hormone in energy homeostasis and neuroendocrine function, has a permissive role in the pathogenesis of reproductive dysfunction. Aim of the study To assess the role of serum leptin in women with PCOS and to evaluate leptin levels in PCOS women before and after treatment with metformin. Materials and Methods This prospective experimental study included 60 women of reproductive age (18 - 38years) were allocated to four groups : 15 obese women with PCOS (BMI >30 kg/m2), 15obese controls, 15 non - obese women with PCOS (BMI 18 - 30 kg/m2), and 15 non - obese controls. Serum leptin and insulin levels were measured and compared between case and control subjects also comparison done before and after treatment with metformin. Results There was a significant increase in leptin in non - obese PCOS group (8.2±2.73) compared to non - obese control (5.64±1.43), (P value=0.0032), insulin level was significantly higher in PCOS group (15.87±6.65) than control (5.47±1.68), (P value<0.001). There was significant decrease in BMI, leptin and insulin levels after 12 weeks of metformin treatment in obese and non - obese PCOS subjects. Conclusions Leptin level increased remarkably with increasing body weight. It is higher in non - obese PCOS women in comparison with non - obese healthy women. Treatment with metformin for 12 weeks resulted in significant reduction in leptin levels in both obese and non - obese PCOS subjects.

مقارنة نسب الحمل للنساء اللواتي يعانين من توقف الطمث لاسباب ثانويه بعد استعمال ادوية المنشطه للحويصلات المبيضيه باستخدام التمنيه داخل الرحم والطريقه الطبيعيه للحمل == Comparison of Pregnancy Rate Between Intrauterine Insemination And Spontaneous Pregnancy After Ovulation Induction In Women With Secondary Amenorrhea

Author name: سوسن كاظم عبد الامير
Supervisor name: محمد باقر محمد رشاد فخر الدين
General topic: Biology
Specific topic: Biotechnologies
Degree: Master
Language: English
University location: Baghdad
First pages:
Abstract: انقطاع الطمث لاسباب ثانوية هو انعدام الدوره الشهريه لمدة ثلاثة الى ستة اشهر للنساء اللواتي لهن دوره شهريه منتظمة.واستنادا لمنظمة الصحة العالمية ان انقطاع الطمث يتضمن مجموعة (WHOI) و(WHOII) والتي تكون (30%) من حالات العقم.وتعاني اكثر النساء ممن يكونون من م | Secondary amenorrhea refers to the lack of cycle for three months in a row or for more than six months in a woman who has had regular menstrual periods before, and its associated with conditions classified as World Health Organization (WHO) group 1 and WHO group 2 and has been estimated to represent almost (30%) of all causes of infertility. In clinical practice, WHO group 2 subjects present much more frequently than WHO group 1 subjects and they appear to be much harder to treat successfully. Among women classified as WHO group 2, those diagnosed with polycystic ovary syndrome (PCOS) constitute the largest group (60 - 85% of cases). These women account for most cases with oligomenorrhea (90%) and represent about (30%) of those with amenorrhea.ObjectiveThe aim of this study was to find out the pregnancy rate following intrauterine insemination (IUI) in women complaining of secondary amenorrhea after induction of ovulation and compare it with those achieve pregnancy by natural way.Material and MethodsSeventy five females with secondary amenorrhea were involved in this study, there ages were ranged between (?30, 30 - 39, ?40) years old with infertility duration ranged between (?2, 3 - 4, 5 - 6, 7 - 8, ?9) years. History and medical examination were done for all women, with tubal patency assessment by HSG or laparoscopy.By cycle day two, hormonal assay (S.FSH, S.LH, S.E2, S.Prolactin and S.Testosterone) were done for all females in addition to ultrasonography to exclude any ovarian pathology.Ovulation induction program was applied for all females which include either clomiphene citrate (CC) alone, recombinant Follicular Stimulating Hormone (r - FSH) alone or combined CC and r - FSH. Vaginal ultrasonography was done for all females on day 12 or13 to assess ovarian response (size and number of mature follicles) and endometrial thickness. Meantime all male partners undergo seminal analysis to assess sperm parameters (sperm concentration, sperm motility and morphology).Thirty eight of females participated for natural pregnancy and thirty seven of females participate for IUI. Washing swim up technique was used for sperm activation for all male partner involved in IUI group.Follow up of all these females for pregnancy test to assess the pregnancy rate for both groups (natural and IUI).ResultsThe pregnancy rate achieved by natural way for a women with secondary amenorrhea is (23.7%), and (18.92%) by IUI way.In this study, it was found that female age, infertility duration, hormonal balance and ovulation induction program affect the pregnancy outcome where the young age group and short infertility duration correlate positively with pregnancy rate. Furthermore, early diagnosis of underlying causes of secondary amenorrhea to achieve hormonal balance by suitable ovulation induction program, have an effect on pregnancy rate, were combined CC and r - FSH produce a significant result among females achieve pregnancy by natural way (13.5%) compared with other ways. While ovulation induction by r - FSH drugs produce a significant results (13.5%) among females achieve pregnancy by IUI way.ConclusionFrom results of this study, it was concluded that young female age, short infertility duration, early diagnosis of underlying causes of secondary amenorrhea and the use of r - FSH drugs for ovulation induction produce a high significant pregnancy rate using IUI program.

دراسة مقارنة بين تاثير سترات الكلوميفين وسترات التاموكسيفين على بعض معايير نطف الفئران == Comparative Study On The Effects of Clomiphene Citrate And Tamoxiphene Citrate On Some Sperm Parameters In Mice

Author name: رائد عبد الاله عباس
Supervisor name: محمد باقر محمد رشاد فخر الدين | محمد عوده سلمان
General topic: Biology
Specific topic: Zoology - Embryology
Degree: Master
Language: English
University location: Baghdad
First pages:
Abstract: يعد العقم واحدة من المشاكل الاجتماعية المهمة في معظم انحاء العالم.استنادا الى الاحصائيات الحالية حوالي 15% من المتزوجين يواجهون العقم. يؤدي تقييم السائل المنوي غير الطبيعي للاستروجينات الى تشخيص قلة اعداد النطف ونشاطها وشكلها الطبيعي ومن ناحية اخرى تؤثر | Infertility is one of the most critical social problems in the all of population world. According to the current statistics, about 15% of married couples face with infertility. Assessment of abnormal semen parameters leads to diagnosis of oligoasthenoteratozoospermia, and in others, it leads to isolated abnormalities of sperm concentration, motility, and morphology, due to the lack of differentiable or correctable etiology, Both clomiphene citrate and tamoxiphene citrate, as an anti - estrogen, is the most common prescribed medication for male infertility. In humans, ant estrogens interfere with the normal negative feedback of sex steroids at the hypothalamus and pituitary, thereby increasing endogenous gonadotropin releasing hormone (GnRH) secretion from the hypothalamus and follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion directly from the pituitary. Objective : The objective of this study was to investigate the effect of clomiphene citrate (CC) and tamoxiphene citrate (TC) administered to male mice on quality of sperm parameters.Materials and Methods : Ninety six male mice were divided into two major groups, and every one of these groups was subdivided into three minor groups involving control and two treated groups. In the CC study, 48 mice were administrated orally 0, 0.0125 mg and 0.025 mg as control (G 1), low dose (G 2) and high dose (G 3) for 42 days. While, in the TC study, 48 mice were administrated orally 0, 0.01 mg and 0.02 mg as control (G 1), low dose (G 2) and high dose (G 3) for 42 days. Then, the male mice were sacrificed, both vas deferens were collected and assessment sperm parameters involving sperm concentration, sperm motility and activity, and normal sperm morphology. Results : The results of present study appeared that the use high dose of CC or TC significantly increment (P<0.05) sperm concentration as compared to control groups. However, use high dose of CC significantly increment (P<0.05) percentages of sperm motility and normal sperm morphology. Meanwhile, the percentage of progressive sperm motility was increased significantly (P< 0.05) when low CC dose administered as compared to control and high CC dose groups. In this study, percentages of sperm motility, progressive sperm motility and normal sperm morphology showed best elevation when used low TC dose as compared to both control and high TC dose groups. High TC dose causes significant increment (P<0.05) in the percentage of sperm agglutination when compared to control and low TC dose groups.Conclusions : Based on the results of this study, it can be concluded that the administration of high dose of either CC or TC increases sperm concentration, while administration of low dose of either CC or TC enhances progressive sperm motility.

تاثير الادينوسين ثلاثي الفوسفات على اخصاب وتطور الاجنة الاولي خارج الجسم الحي في الفئران كنموذج للجنس البشري == Effect of Adenosine Triphosphate On In Vitro Fertilization And Early Embryonic Development In Mice As A Model For Human Being

Author name: مهند علي مشكور
Supervisor name: محمد باقر محمد رشاد فخر الدين | نوال خيري العاني
General topic: Biology
Specific topic: Zoology - Embryology
Degree: Master
Language: English
University location: Baghdad
First pages:
Abstract: يعد الاخصاب خارج الجسم الحي (IVF) من احد اهم التقنيات المستخدمة لانتاج اعداد كبيرة من الاجنة لبحوث التطور الاساسيه والبيولوجيا الجزيئية لنضوج البويضات المختبري والاخصاب. يعتمد الاخصاب خارج الجسم الحي وظروف حفظ الجنين المثلى على مكونات الوسط الزرعي كونها ا | In vitro fertilization (IVF) is one of the most important techniques used to produce large numbers of embryos for research into the basic development and molecular biology of in vitro oocytes maturation and fertilization. Optimal IVF and embryo culture conditions depend on the composition of culture media being the most important determinants of success in vitro interaction of the gametes and subsequent embryo development. Adenosine 5 - triphosphate (ATP) is a fundamental factor to maintain life, by providing energy, and controlling the cell function and metabolism. Objectives : The present study aims to investigate the effect of ATP supplied to SMART medium on a rate of fertilization and early embryonic development (ED) in mice as a model for human beings.Materials and Methods : The female mice (90) were superovulated using superovulation program to produce a large number of oocytes. These were divided into three groups, the first group was inseminated with vassal sperm in vitro alone (control); the seconed group (G2) was inseminated with vassal sperm in vitro using SMART medium enriched with low concentration of ATP(1.25mM). The third group (G3) was inseminated with vassal sperm in vitro using SMART medium enriched with high concentration of ATP (2.5mM). Mouse spermatozoa were collected from both vasdeferens. Then sperm parameters were assessed after 30 min. IVF technique was performed for 3 groups, and assessed after 20 - 22h. Then, percentages of early embryonic development stages and abnormal embryos morphology (%) for each embryo stage were assessed.Results : Results of the present study revealed significant increment (P<0.05) in the in - vitro fertilization (%) when using 1.25mM ATP as compared to 2.5 mM ATP and the control group. Significant differences (P<0.05) in the 1 - cell stage were assessed in 2.5mM compared with 1.25mM groups and the control group. Also, Significant differences (P<0.05) in the 2 - cell and 4 - cell stage were assessed in 1.25mM ATP compared with other groups. However, non significant differences in the percentages of abnormal embryos morphology were reported between both treated groups of ATP.Conclusion : From the results of present study it was concluded that the low ATP concentration (1.25mM) enriched to the culture medium improved the percentage of in vitro fertilization and early embryonic development.

العلاقة بين متلازمة تكيس المبايض وهرمون المضاد لمولر وبرامج تحريض الاباضة عند اجراء عملية التمنية داخل الرحم

Author name: عبير ناظم جاسم
Supervisor name: محمد باقر محمد رشاد فخر الدين | صباح مهدي حسين
General topic: Biology
Specific topic: Biotechnologies
Degree: Higher Diploma
Language: English
University location: Baghdad
First pages:
Abstract: تعد متلازمة المبيض متعدد الا كياس هي من اكثر امراض الغدد الصماء شيوعا عند النساء حيث يصاب من النساء في سن الانجاب مايقارب (5 - 10%). الاعراض الرئيسيه لمرض متلازمة المبيض متعدد الاكياس هو اضطراب الدوره الشهريه مع فشل لاباضه وظهور اعراض زيادة الهرمون الذكر

نوعية البويضة والتكوين الجنيني بعد الاعطاء الفموي للسبيرماكس لاناث الفئران : موديل تجريبي للبائن == Oocyte Quality And Embryonic Development After Oral Administration of Speramax® In Female Mice : Experimental Model For Mammal

Author name: هبة صاحب حمزة
Supervisor name: سعد صالح الدجيلي
General topic: Biology
Specific topic: Zoology - Embryology
Degree: Master
Language: English
University location: Baghdad
First pages:
Abstract: Background : Speramax® has been found to play an important role in sperm function characters and males reproductive performance with no studies on its effects on the oocyte maturation and embryonic development in females.Objective : The goal of the thesis is to examine the effect of Speramax ® on oocyte maturation. And to emphasize the effect of Speramax ® on ova quality, embryonic development and newborn. Materials and Methods : Speramax ® treated by oral administration for 1, 2 and 4 weeks. A hundred and twenty six female mice were randomly divided into four groups, the first group was treated without Speramax® with superovulation(SUO) while the second group were treated by Speramax® with SUO and the third group were superovulated only and the fourth group was not treated and spontaneously ovulated (SPO) and considered the control group(thirty two mice). Results : The results indicated that the treatment with Speramax® showed a positive effect on oocytes maturation in vivo. There was a highly significance (p? 0.0001) improvement in number of mature oocytes following treatment with Speramax® in SPO and SUO mice compared with SPO and SUO mice not treated with Speramax®. The embryonic developmental rate after 24 and 48 hours of mating in treated groups with Speramax® was significantly (p? 0.05) higher than those of SPO and SUO mice too.The study showed that the quantity and quality of embryos generated from the treated groups were superior to that of untreated groups.Conclusion : It was concluded that the treatment by Speramax® has a great improvement on oocyte maturation, early embryonic development and embryo grading quality of mice embryos with an increase in the numbers of mice newborn.
1 2 3