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الظواهر الوجهية والفموية، عوامل الاكسدة ومضادات الاكسدة في مصل ولعاب مرضى فقر الدم البحر الابيض المتوسط نوع بيتا في مدينة كربلاء == Oro - Facial Manifestations, Oxidative Stress And Antioxidants Markers In Serum And Saliva of Patients With Beta Thalassemia Major In Karbala City

Author name: مؤيد صاحب عباس شمسه
Supervisor name: تغريد فاضل زيدان
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
Language: English
University location: Baghdad
First pages:
Abstract: Thalassemia is a hereditary anemia resulting from defects in hemoglobin production. Beta Thalassemia, which is caused by a decrease in the production of beta globin chains, affects multiple organs and is ssociated with considerable morbidity and mortality. Aims of the study : The aims of this study were to study the oro - facial manifestations in beta thalassemia major patients and evaluation of the oxidative stress status in serum and saliva represented by malondialdehyde as xidative stress indicator and also assessment of serum and saliva antioxidants which are ceruloplasmin and uric acid in beta thalassemic patients with and without periodontitis and compared that with the healthy individuals in addition to investigate the relation between the clinical findings and laboratory investigations.Methods : Eighty seven (87) subjects were consented and contributed in this study, twenty eight (28) thalassemic patients with periodontitis, thirty (30) thalassemic patients without periodontitis and twenty nine (29) healthy subjects that were age matched with the patients. Oral examination has been done for each subject. Serum and saliva sample have been taken from each subject for analysis, to study malondialdehyde as oxidative stress and antioxidants ceruloplasmin and uric acid.Results : Malocclusion was the most common prevalent oro - facial manifestations (60%), followed by rodent face (35%), brown pigmentation of oral mucosa (23%) and incompetent lip (8%). The mean serum and saliva malondialdehyde were significantly higher in thalassemic patients with periodontitis than that in thalassemic patients without periodontitis and healthy subjects (p<0.001), while the mean serum and saliva ceruloplasmin were significantly higher in control group than that in other study groups (p<0.001). The mean serum uric acid was significantly higher in thalassemic patients without periodontitis than that in thalassemic patients with periodontitis and healthy subjects (p<0.001) and the mean saliva uric acid was significantly higher in thalassemic patients without periodontitis (p<0.05) compaired with thalassemic patients with periodontitis and healthy subjects. The results of this study showed that there were no significant correlation between serum and saliva malondialdehyde in any of study groups, while there was a positive significant linear correlation between serum and saliva ceruloplasmin in thalassemic patients with periodontitis (p<0.05), a negative significant linear correlation in healthy subjects (p<0.05) , a positive significant linear correlation in thalassemic patients without periodontitis (p<0.001). The results showed that there was a positive significant linear correlation between serum and saliva uric acid in thalassemic patients with periodontitis (p<0.05), a positive significant correlation in thalassemic patients without periodontitis (p<0.001) and no significant correlation between serum and saliva in healthy subjects. On the other hand there were no significant correlation between serum and saliva (malondialdehyde, ceruloplasmin and uric acid) and clinical attachment loss (p>0.05), except a positive significant linear correlation between clinical attachment loss and salivamalondialdehyde (p<0.05) was found. Conclusions : Malocclusion was the most prevalent oro - facial manifestations of beta thalassemia major patients. Oxidative stress play a significant role in the pathogenesis of beta thalassemia ,which was the main cause of red blood cells destruction represented by significant elevation of serum and saliva malondialdehyde and significant reduction of ceruloplasmin. Also oxidative stress remain contributing factor in periodontal tissue destruction, which was appeared as a significant increased level of saliva malondialdehyde and decreased saliva ceruloplasmin in patients with periodontitis and there was a significant correlation between saliva malondialdehyde and clinical attachment loss

Assessment of The Oral Findings, Salivary Oxidative Status And Iga Level Among Group of Workers Exposed To Petroleum Pollutants In Al - Daura Oil Refinery

Author name: امير سعد حمزة
Supervisor name: Jamal Noori Ahmed
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
Language: English
University location: Baghdad
First pages:
Abstract: Petroleum is perhaps the most important substance consumed in modern society. Petroleum is unique and s a complex mixture of thousands of compounds. Oil refinery workers are continuously exposed to numerous hazardous materials and working conditions that place them at continuous risk of injury and death.Petroleum contains the heavy metals as a natural constituent or as additives. The main threats to human health from heavy metals are associated with exposure to lead, cadmium, mercury and arsenic. Several carcinogenic metals such as arsenic, cobalt, chromium, lead, mercury, and nickel induce redox reactions in living systems. These metals induce the production of reactive oxygen species in both in vivo and in vitro systems. These radicals have rendered oxidative damage to deoxyribonucleic acid, proteins, and lipids. Secretory immunoglobulin A is the main immunoglobulin found in mucous secretions from the tear glands, salivary glands, mammary glands, the respiratory system, the genito - urinary tract, and the gastrointestinal tract.Aims of the study Assessment of the salivary levels of heavy metals among the workers of Al - Daura oil refinery, assessment of the oxidative status in the oral cavity of the workers by measurement of Malondialdehyde and Superoxide dismutase markers,assessment of the oral immunological activity by measurement of secretory immunoglobulin A level in saliva and Assessment of the oral findings among the workers.Subjects, Materials and Methods This study was done in Al - Daura oil refinery, samples consist of 60 workers involved in refining processes as study group subdivided into three subgroups which represent the different sections in the refinery and 20 subjects not involved in refining processes as control group. Oral examination and saliva collection was done to assess the oral findings and measure the level of heavy metals (lead and cadmium), oxidative status (Malondialdehyde and Superoxide dismutase) and secretory IgA.Results The mean of salivary lead and cadmium was higher in study group (6.34 ?g/dl and 0.56 ?g/l respectively) than that of control group (3.3?g/dl and 0.34 ?g/l respectively) with highly significant difference (p

Evaluation Of Bleaching Effect On Microhardness And Morrphological Appearance On Enamel In Children

Author name: ندى عبد الواحد شنان
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
Language: English
University location: Baghdad
First pages:

حالة ما حول الاسنان عند المرضى الذين يتعاطون العقارات الغير استيرودية المانعة للالتهاب : دراسة سريرية

Author name: زينب عزيز عبد الامير
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تاثير ازالة طبقة الجليط على قوة ثبات وتد التيتانيوم المتوازي المسنن المثبت بالسمنت الزجاجي

Author name: جوني بطرس شمو
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

قوة الارتباط القصية للمادة السادة للجذور بالنسبة الى عاج السن

Author name: ميعاد عبد الرزاق العاني
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

سعة انتشار الالتهاب العدواني للانسجة ماحول السنية للشباب البالغين في محافظة النجف

Author name: حيدر رعد عبد الباقي
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تقييم العلاقة المتبادلة بين محور جسد الفك السفلي ومستوى الفك السفلي في قياس دوران الفك السفلي التاتج عن النمو المختلف لاصناف الهيكلية

Author name: اسامة سعد صادق
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تحضير وتشخيص البوليمر الاسهامي للبولي مثيل ميثاكريليت المطعم باللكنين وتقيم تاثيره على بعض مواصفات قاعدة طقم الاسنان الاكرلي

Author name: انتصار جميل اسماعيل
General topic: Dentistry
Specific topic: Dentistry
Degree: Doctorate
University: University of Baghdad
University location: Baghdad

تاثير نظام على تكيف قاعدة طقم الاكريللك في النماذج المختلفة للحنك

Author name: فرح نبيل محمد طاهر
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

العلاقة بين تراكب الاسنان مستوى اطباق الاسنان، ودرجة الميل المحوري للقواطع في العضة الطبيعية والعضة العميقة لاشعة الوجه القياسية الجانبية

Author name: همسة خلدون طارق
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

Dental Caries And Salivary Mutans Streptococci Level Among Agroup Of Mothers And Their Children In Relation To Feeding

Author name: نهى شوكت الشمري
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تقييم مدى انطلاق ايونات الكالسيوم والهيدروكسيل من معجون هيدروكسيد الكالسيوم غير المتصلب ومن تكتل ثلاثي الاوكسيد المعدني من خلال ثلاث احجام مختلفة لذروة جذر السن خلال عملية علاج ذروة جذر السن المفتوح

Author name: سارة طالب عبد القادر
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

قوة الربط القصي لخزف الاسنان المدمج مع معدن النيكل كروم المعاد

Author name: عارف سلمان الكبيسي
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

عضة الامامية المتعاكسة لطلبة عراقيين تتراوح اعمارهم 7 - 11 سنة : دراسة مستعرضة

Author name: شذى عبد الواحد القيسي
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

دراسة مختبرية لتقييم تاثير استخدام مزيل التسوس الكيميائي الميكانيكي الجديد على التسرب المجهري لحشوة الراتنج باستخدام نوعين من عوامل الربط ولفترات زمنية مختلفة

Author name: زينب محمود منسي العبيدي
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

دراسات للتغيرات النسيجية المرضية، نيسجية كيميائية، التراكيب المستدقة والكيميائية الحياتية للغدة اللعابية تحت الفكية في الجرذ المصاب بداء السكري المحدث عن طريق الغذاء والالوكسان : دراسة تجريبية

Author name: ايمان عبد الرزاق خلف
General topic: Dentistry
Specific topic: Dentistry
Degree: Doctorate
University: University of Baghdad
University location: Baghdad

حالات الالتهاب، مؤشرات الالتهاب، بعض المتثابتات الكيميائية الحياتية وبعض المناسب الفمية لدى مرضى داء السكري نمط 1 الاطفال والمراهقين

Author name: سرى علي احمد
General topic: Dentistry
Specific topic: Dentistry
Degree: Doctorate
University: University of Baghdad
University location: Baghdad

تحضير مادة السيليوز المؤكسد في العراق وتقييم كفاءته كيميائيا وسريريا

Author name: محمد هلال الشجيري
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تحدد فتحة الفم التشخيص والمعالجة

Author name: صالح جوحي جاني
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تاثير علك المستك على اللويحة الجرثومية السنية

Author name: محمد شوكت عطية
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تاثير تعاطي موانع الحمل الفموية على اللثة

Author name: نهى عكاب حامد
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تاثير المواد التعويضية والحفر المحضرة على معامل المرونة في الضواحك

Author name: ايمان حكمت هنودي
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تاثير المجال الكهرومغناطيسي المتذبذب على حركة الاسنان التقويمية

Author name: سامر رمزي متي
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad

تاثير التخديش الحامضي والقصف الرملي لقواعد الحاصرات التقويمية المعدنية على قوة الاصرة

Author name: عبد الله عبد المعبود
General topic: Dentistry
Specific topic: Dentistry
Degree: Master
University: University of Baghdad
University location: Baghdad
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