Author name:
حسين مهدي حسين الخفاجي
Supervisor name:
يسار محمد حسن الشماع
University location:
Najaf
Abstract:
في هذه الدراسة العرضية, تم اختيار 140 شخصا بصورة عشوائية, من بينهم 90 كان مصابا بالسكري والباقون كانوا سليمين ,لدراسة تاثير ارتداء طقم الاسنان الكلي والجزئي من قبل مرضى السكري على فحوصات كفاءة الرئتين وبالتحديد, , السعة الحيوية القسرية (FVC)و الحجم الزفير | In this cross sectional study, a total number of 140 subjects selected randomly, 90 of them were diabetic and the remaining were normal, to study the effect of complete and partial dentures wearing by diabetic patients on pulmonary function test particularly peak expiratory flow rate (PEFR), forced expiratory volume in the first second (FEV1), forced expiratory volume ratio (FEV1/FVC) ratio (FEV1%), forced vital capacity (FVC), and also the retropharyngeal space (RPS), the level of Endothelial selectin (E - selectin) and the level of Vascular Cell Adhesion Molecule - 1(VCAM - 1)was also compared, in this study, between the diabetic and the normal subjects.The results indicate that the spirolab III was accurate and reproducible and can be used in all related studies.The effect of wearing of complete and partial dentures by diabetic patients on FVC, FEV1, PEFR and also the degree of alteration of the RPS were measured.1) The results of the study shows a significant increase in values of FEV1, FEV1%, PEFR and retropharyngeal space (RPS) (p<0.05), while there was no significant change in the value of FVC after the replacement of complete denture.2) No statistically significant differences in the values of FVC, FEV1, FEV1%, PEFR and retropharyngeal space (RPS) was observed after replacement of partial denture without free end extension3) There was a significant increase in values of FEV1, FEV1%, PEFR and retropharyngeal space (RPS) (p<0.05), never the less there was no significant change in the value of FVC after the replacement partial denture with unilateral free end extension.4) There was a significant increase in values of FEV1, FEV1%, PEFR and retropharyngeal space (RPS) (p<0.05), However there was no significant change in the value of FVC after the replacement partial denture with bilateral free end extension5) The results showed that in poor and good control diabetic patients there was a significant decrease in the values of FEV1, PEFR, FEV1%and RPS after the removal of all types of dentures(p<0.05), while no significant change in FVC.6) Statistical significant increase in Serum E - selectin and VCAM - 1 level was found in diabetic patients when compared to that of the normal subjects (p<0.05).7) No statistical significant difference between serum E - selectin and VCAM - 1 level in diabetic patients after and before denture placement (p>0.05). The cause of the significant change in the values of FEV1, FEV1%, PEFR and retropharyngeal space (RPS) in case of complete and partial denture with free end extension replacement may be due to pressing of the retropharyngeal space bilaterally and unilaterally by the complete and partial denture and the FVC was not significantly changed because it may not be affected by denture support, while the elevated Serum E - selectin and VCAM - 1 level might indicate endothelial activation and inflammation.In conclusion we can conclude that 1. The spirolabIII used in this study is an accurate and reproducible device and can be used in the assessment of lung function test.2. Values of FEV1, FEV1%, PEFR and retropharyngeal space (RPS) where significantly higher after the replacement of complete denture and partial denture with bilateral and unilateral free end extension in diabetic patients (p<0.05), while there was no significant change in the value of FVC.3. No statistically significant differences in the values of FVC, FEV1, FEV1%, PEFR and retropharyngeal space (RPS) was observed after partial denture without free end extension has been replaced in diabetic patients.6. In poor and good control diabetic patients there was no significant change in the value of FVC, while the values of FEV1, PEFR, FEV1%and RPS where significantly decrease after the removal of all types of dentures.8. Statistical significant increase in Serum E - selectin and VCAM - 1 level was found in diabetic patients when compared to that of the normal subjects.9. The results for serum level of E - selectin and VCAM - 1 shows no significant difference diabetic patients after the placement of all types of dentures (p>0.05).
