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دراسة وتصنيع اقطاب عالية الحساسية لتقدير وتشخيص العناصر الثقيلة في المركبات الصيدلانية == Studies and Industrialisation of high sensitive electrodes for determination and characterization of heavy metal in pharmaceutical compounds

Author name: عماد سلام عبود شلاكة

Supervisor name: عامر موسى جودة | مثنى صالح مشكور

General topic: Chemistry

Specific topic: Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

دراسة تجريبية ونظرية للمعقدات الجزيئية ل 6-ميركابتوبيورين (6-MP) و6- ثيوغوانين (6-TG) ومشتقاتها وتقدير نشاطها مع المستقبل HGPRT

Author name: الاء عبادي حبيب

Supervisor name: فلاح شريف سهيل

General topic: Chemistry

Specific topic: Physical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

تحضير وتشخيص ودراسة الفعالية الحيوية لبعض مشتقات البيريميدين الجديدة ابتداء من حامض الميلدرم

Author name: رنا نعمة عطية

Supervisor name: ناجي موسى علي

General topic: Chemistry

Specific topic: Organic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

تحضير وتشخيص ودراسة الفعالية الحيوية لبعض المشتقات الجديدة للبيتا لاكتام

Author name: رضية عبد الباقي خضر

Supervisor name: عزت حسين زمام

General topic: Chemistry

Specific topic: Organic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

تحضير متراكبات نانوية من بعض الاكاسيد المعدنية والبولي ثايوفين مضادة للتاكل ومعالجة للمياه

Author name: هناء كاظم

Supervisor name: عامر موسى

General topic: Chemistry

Specific topic: Physical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

Synthesis, characterization ,theoretical,thermal and biological study of new Schiff bases derived from dimedon and their cpmplexes for some metal ions

Author name: وليد محسن سرحان

Supervisor name: عباس علي صالح | حسين جاسم محمد

General topic: Chemistry

Specific topic: Inorganic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

Synthesis and characterization of biopolymer nano composite based on modified clay using organic nitrogen compounds

Author name: منار غياث عبد المطلب

Supervisor name: عماد عباس جعفر الملا | ماجد جاري محمد

General topic: Chemistry

Specific topic: Organic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

Studies of Electrochemical and Geometrical Parameters for Anticancer Drug 5 - Fluorouracil with Respiratory Chain Components:Computerized and In Vitro Modes

Author name: رزاق عبد الـزهرة ابراهيم حمود العامري

Supervisor name: فلاح شريف عبد سهيل | حسين كاظم الحكيم

General topic: Chemistry

Specific topic: Physical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

Assessment of Some Factors as a Risk Predicators for cardiovascular, in Iraqi Impaired Glucose Tolerance Obese Patients

Author name: دنيا محمد رضا محمد علي

Supervisor name: هناء عداي علي

General topic: Chemistry

Specific topic: Biochemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

تصميم منظومة حقن جرياني جديدة لتقدير الهيدرازين و بعض الادوية الامينية في التراكيب الدوائية == Construction of a new flow injection system for the determination of hydrazine and some amine drugs in pharmaceutical formulations

Author name: احمد عدنان عبد الامير

Supervisor name: مثنى صالح مشكور | داخل ناصر طه

General topic: Chemistry

Specific topic: Analytical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

تحضير و توصيف و الخصائص الطيفية الكهربائية لبعض كواشف الازو الجديدة غير المتجانسة الحلقة واستعمالها في التقدير الطيفي لايونات بعض العناصر الفلزية == Synthesis,characterization and electrochemistry spectroscopic properties of some new azo heterocyclic reagents and using their for determination of some metal ions

Author name: فاطمة عباس خزعل الموسوي

Supervisor name: حسين جاسم محمد

General topic: Chemistry

Specific topic: Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

متحسس - ابتمر الكتروكيميائي عالي الحساسية للكشف المبكر عن التهاب الكبد الفايروسي نوع B == Ultrasensitive Electrochemical Aptasensor for Earlier Detection of Hepatitis B Virus

Author name: ضياء حسين محسن

Supervisor name: مثنى صالح مشكور | فتانة فاطمي

General topic: Chemistry

Specific topic: Physical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

تحضير محفزات متراكبة نانوية ثانوية وثالثية لاوكسيد المغنسيوم MgO عالية النشاط وتطبيقاتها البيئية == Preparation of High Activity Binary and Ternary MgO Nanocomposites Catalysts and their Environmental Application

Author name: فاطمة علاوي عبد السجاد الحجامي

Supervisor name: عامر موسى جودة سامي وحيد راضي

General topic: Chemistry

Specific topic: Physical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

تحضير وتشخيص ودراسة بعض الخواص الحرارية لبوليمرات الماليئيمايد تحتوي على ادوية سلفا == Synthesis, Characterization and Thermal Study of Some New Maleimide Polymers Contain Sulfa Drugs

Author name: احمد وحيد راضي

Supervisor name: عزت حسين زمام

General topic: Chemistry

Specific topic: Organic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

تحضير وتشخيص ودراسة الفعالية الحيوية لمشتقات الكلوكوز الكلايكوسيدية الجديدة == New Glucoside Derivatives Synthesis, Characterization and Biological Activity

Author name: مصطفى كاظم نعيم

Supervisor name: عزت حسين زمام

General topic: Chemistry

Specific topic: Organic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

التغيرات الكيموحيوية والمناعية عند مرضى الثالاسيميا العظمى المصحوبة بالكابة == Biochemical and munological Changes in Major Thalassemia Patients with Depression

Author name: اساور حسن نجم

Supervisor name: حسين كاظم الحكيم

General topic: Chemistry

Specific topic: Biochemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

المؤشرات الحيوية المناعية لنقص الادراك في المرضى العراقيين المصابين بمرض الفصام المقاوم للعلاج == Immune Biomarkers of Cognitive Deficits in Iraqi Patients with Treatment Resistant Schizophrenia

Author name: عباس فاضل عباس محمد

Supervisor name: حسين كاظم الحكيم

General topic: Chemistry

Specific topic: Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

دراسة حاسوبية لمحاكاة حيوية لنموذج معقدات الروثينيوم والحديد العنقودية لاختزال النيتروجين == Computational Study on Biomimetic Model Ruthenium and Iron Clusters for Reduction of N2

Author name: خلود عبيد كزار المسعودي

Supervisor name: محسن عبود محسن العبادي | سميرا شامل

General topic: Chemistry

Specific topic: Physical Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

تحضير وتشخيص بعض معقدات الازو الجديدة وتقدير فعاليتها البايولوجية == Synthesis, Characterization of Some New Azo Complexes and Evaluation of Biological Activity

Author name: نور الهدى باسم عبد مجي

Supervisor name: ساجد محمود لطيف | حسين كاظم الحكيم

General topic: Chemistry

Specific topic: Inorganic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

تحضيرو تشخيص والفعالية الحيوية لبعض المشتقات الجديدة للبيتا لاكتام ثنائية الحلقة لسكر D- مانيتول == Synthesis , Characterization and biological activity of some new bis ?-lactam derivatives from D-mannitol

Author name: ايمان عبد الوهاب عبد الله الكويتي

Supervisor name: عزت حسين زمام

General topic: Chemistry

Specific topic: Organic Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

دراسة نظرية بولاروغرافية وطيفية لفعالية ومدى استقرارية المعقدات الجزيئية لحاجزات بيتا مع مستقبلاتها == Theoretical , polarographic and spectroscopic study of activity and molecular complex stability for beta blockers compounds with their receptors

Author name: اوراس عدنان حاتم

Supervisor name: فلاح شريف عبد سهيل | عامر موسى جودة

General topic: Chemistry

Specific topic: Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

قياس المتغيرات الكيموحيوية والجين المثبط لفعالية البلازمنوجين للتلقيح في الانابيب == Estimation the Biochemical Parameters and Plasminogen Activator Inhibitor-1 (PAI-1) gene Polymorphism in Vitro Fertilization

Author name: ايمان محمد جبر حمزة

Supervisor name: حسين كاظم عبد الحسين الحكيم

General topic: Chemistry

Specific topic: Analytical Biochemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

التناظر الجيني للجينات ذات العلاقة بمرض السكري كمؤشر لامراض القلب الاقفاريه لدى مرضى السكري من النوع الثاني في محافظه النجف الاشرف == Single Nucleotide Polymorphism of Diabetic Related Genes as Predictor for Ischemic Heart Diseases in Type 2 Diabetic Patients in Al-Najaf Governorate

Author name: رشا شاكر نعمة

Supervisor name: ماجد كاظم حسين | حسين جاسم محمد

General topic: Chemistry

Specific topic: Analytical Biochemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

تطبيقات طريقة استخلاص سائل - سائل للفصل والتقدير الطيفي لبعض العناصر الانتقالية بواسطة معقدات عضوية جديدة == Applcations of Liquid - Liqid Extraction Method For Separation And Spectrophotometric Determiination To Some Transition Metal Elements By New Organic Reagents

Author name: احمد ابراهيم حمزة

Supervisor name: شوكت كاظم جواد

General topic: Chemistry

Specific topic: Biochemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: Arabic

University location: Najaf

First pages:

Abstract: اجريت هذه الدراسة لمعرفة تاثير مرض ارتفاع ضغط الدم على بعض المتغيرات الكيموحيوية في الدم, ومقارنتها مع القيم الطبيعية (مجاميع السيطرة) والبالغ عددهم (125) (47 اناث و72 ذكور) والذين تراوحت اعمارهم بين (21 - 70) سنة حيث تضمن البحث : دراسة 115 حالة مرضية للاش | The present study was carried out to determine the effect of hypertension on some biochemical parameters in the blood compared to that of normal values of healthy subjects in healthy control group(125) (47 females and 72 males) Their ages ranged between(21 - 70) yearsThe study included : - 1 - seventy hypertensive patients(30 females and 40 males)Their ages ranged between (30 - 80) years the following biochemical parameters were included : (Cho, TG, HDL, LDL, VLDL, GOT, GPT, SOD MDA, HbA1C ,LDH, Metall oendopeptidase , leptin )for both hypertensive patients and health subjects as a control. Results of this study have shown a significant increase(p?0.05) in the concentration of cholesterol, triglyceride ,LDL,VLDL compared with control group while high density lipoprotein showed a significant decrease (p?0.05) compared with control groupThe estimation of LDL/HDL ratio showed a significant decrease (p?0.05) compared to that of healthy subjects The study also included the effect of hypertension duration on BMI and age in relation to the concentration of (Cho, TG ,LDL,VLDL,HDL)The study showed increase in the concentrations of (Cho, TG ,LDL,VLDL) while a decrease in the concentrations of high density lipoprotein for all patients compared with that of healthy subjects (control group).A clinical study of Metallo endopeptidase on the serum of healthy and hypertensive patients was carried which has been shown that the activity of this enzyme in healthy subjects does not affect by sex, age, and smoking while there is significant increase in the activity of Metallo endopeptidase in the serum of the hypertensive patients for both sexes at different ages compared with that of control group while there was an increase in the activity of Metallo endopeptidase in relation to the duration of disease the result also demonstrated a significant increase in the activity of lactate dehydrogenase in hypertensive patients compared with that of control group.ALT and AST enzyme levels have been estimation in this study which showed a significant increase in the level of AST in hypertensive patients for both normal weight and overweight compared with that of control group, while ALT level showed no significant difference in hypertensive patients for both normal weight and overweight compared with that of control groupAs for Leptin the study has showed a significant increase in the concentrations of leptin hormone in control group of healthy subject (over weight BMI?25) compared with normal weight(BMI?25) for the same group. the concentration of leptin in all hypertensive patients showed an increase level in relation to age &BMIThis study also included the estimation of SOD and MDA in both hypertensive patients and healthy subjects (control group).It showed a significant decrease in the activity of SOD as the duration increases and there was a significant increase in the level of MDA(P?0.05)in hypertensive patients compared healthy group.Finally the level of (HbA1C) was also studied which no significant difference in hypertensive patients compared with that of control group, while there was a signi

دراسات كيمياء الكم لمركبات الروثينيوم العضوية الفلزية == Quantum Chemical Studies of Ruthenium Organometallic Compounds

Author name: دريد توفيق عريبي الكنبي

Supervisor name: محسن عبود محسن العبادي | حسين جاسم محمد

General topic: Chemistry

Specific topic: Chemistry

Degree: Doctorate

University: University of Kufa - College Of Science - Chemistry Department

Language: English

University location: Najaf

First pages:

Abstract: There are a wide variety of polyphenolic compounds named flavonids. These are extensively distributed in plants, and they are considered to be dietary antioxidants. They occur naturally in broad range of vegetables, fruits, and primarily recognized as the pigments.Many flavonoids have a metallic ion complexation capacity. The study of this capacity is important because it can be used in producing nutritional supplements, medicine, and heavy metal detoxification.Chelation therapy is the use of chelating agents (complexing agents) to detoxify poisonous metal such as mercury, arsenic, and lead by converting them to chemically inert form that can be excreted without further interaction with the body.Lead is considered as one of the most hazards and cumulative environmental pollutants that affect all biological system through exposure from air, water and food sources. It is toxic heavy metals which are known to induce a broad range of physiological, biochemical and behavioral dysfunction in humans. Because of its perverseness in the environment, lead poisoning still remains an important health problem.The polarographic measurements were carried out using differential pulse polarography (DPP), at hanging mercury drop electrode (HMDE) at the optimal conditions for flavonoids which were 1M HCl for Quercetin, Rutin, and Hespertin and 0.01M NaOH for chrysin as a supporting electrolyte.A well - defined two electron reversible reduction and diffusion controlled one wave for these flavonoide were observed, a linear relationship between concentration and diffusion current (id) was obtained with the value of correlation coefficient (r2) near to one, this obey Ilkovic equation. The values of n; the number of electrons transferred in the reduction process were obtained from the slop of the straight line corresponding to E vs. log i/id - i.Addition of flavonoides to a solution of Pb (II) ion, show the appearance of a new peak in a more negative potential than Pb (II) peak, with the gradual decrease in id of Pb (II) ion which suggests the complex formation between them.The stoichiometry and the stability constant of Pb (II) complex with flavonoids were calculated by Lingane equation; a plot of ?Ep vs. log [L] give a straight line, the slope of the line allows the determination of the coordination number (p), and the stability constant were determined from the intercept, the stoichiometry of these complexes were (1 : 1) with a stability constant of : Pb - Quercetine (5.5*107) ? Pb - Rutine (1.3*107) ? Pb - Hespertine (4*106) ? Pb - Chrysin (5.4*104)These measurements also includes the determination of the kinetic parameter of the electrode reaction (Kth, ?n) and the thermodynamic parameters such as ?H, ?G, and ?S.The spectrophotometric measurements were carried out in 50% methanol/water for Quercetin and Rutin, 30% methanol/water for Hespertin and in phosphate buffer of pH - 7 for Chrysin.The electronic spectrum of free flavonoides in methanol solution was mainly characterized by an important absorption band at ? 370 nm (band I) and a second one located at ? 256 nm (band II). Upon addition of lead (II) to the flavonoids solution significant changes are observed in the electronic spectra, a bathochromic shift in band (I) to the extent of ? 40 nm and a shift in band (II) to the extent of ? 7 nm, the change in ?max and the change in the intensities of the bands were due to the coordination between flavonoids molecules and Pb (II) ion.The stoichiometry of the formed complexes were investigated by the method of continuous variation and it were found (1 : 1), the stability constant were calculated also and were found to be in the order of ? 105 to 106.Thermodynamic parameters and kinetic studies were also determined which indicates a second order interaction between lead (II) and these flavonoides.Spectroscopic measurements for (EDTA) Complexation with lead (II) were carried out in order to compare its stability constant with that obtained for flavonoides complexes, due to its application in the treatment of metal poisoning.Stability constant of (EDTA) with Pb (II) complex were in the order of 108 which is much more efficient than flavonoides.