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تحضير بعض مشتقات المركبات الحلقية غير المتجانسة المتضمنة حلقات رباعية وخماسية وسباعية وحلقة البايرازولين وتقييم تاثيرها على انواع مختلفة من البكتريا والفطريات == Synthesis of Some Deriativel Heterocyclic Compounds Containing Four, Five, Seven - Membered Rings And Pyrazol - 5 - One And Evaluate The Biological Activity of Some Bacteria And Fungies
Author name:
هبة حمزة رشيد لطيف التكريتي
Supervisor name:
خالد مطني محمد الجنابي
General topic:
Chemistry
Specific topic:
Chemistry
Degree:
Master
University:
Tikrit University - Faculty Of Education - Chemistry Department
Language:
Arabic
University location:
Salahaddin
First pages:
25T1490 - p.pdf
Abstract:
تتضمن الدراسة عدة اجزاء : الجزء الاول : تحضير مجموعة من قواعد شف من تكثيف البنزلديهايدالمعوض بالمواقع بارا بمجاميع( بارا - برومو، بارا - كلورو، بارا - نايترو، بارا - N,N - ثنائي مثيل امينو بنزالديهايد ) مع معوضات الانلين المختلفة (بارا - امينو اسيتوفينو | This Work was accomplished through the following four part : Part one In this part nine Schiff bases derived from p - substituted benzaldehyde) with (p - bromo aniline , p - amino acetophenon, aniline, 2 - amino phenol were prepared.The electronic spectra in absolute ethanol solution were used to study the intermolecular charge - transfer complexes between the considered Schiff bases as charge donor , and iodine as charge acceptor molecules.The physical parameters of charge - transfer complexes were calculated by applying Bensi - Hildebrand equation. The equilibrium Constants for complexes formation were found to follow (3<4<9<6<7<8<5<1<2) arrangement. The energy of the complexes and extiztion coefficient were found to have the same arrangement shown above. The difference in the values of this physical properties are attributed to structural difference of the molecular (donating and withdrawing substituted groups). KCT values for the complexes were calculated from Bensi - Hildebrand equation and was found to fit the following arrangement ( 9<8<7<4<3<6<5<1<2 ), depending mainly on the types of substituted groups on aniline ring. Part Two Effect of temperature variation on equilibrium constant for the charge - transfer complexes formation were measured by applying Bensi - Hildebrand equation ,which used to estimate the thermodynamic parameter such as (?G0, ?S0 , ?H ) in absolute ethanol. Part Three The kinetic of the formation of charge - transfer complexes in absolute ethanol was studied.The results indicated that, the more stable charge - transfer complexes have higher rate constant formation and the kinetic of CTC was first order. Part Four Photo stability of (1 - 9) Schiff bases against direct sun light was investigated as solution in both ethanol and dimethyl sulfoxide DMSO.The results indicated that, the rates of photo decay of the Schiff bases in ethanol were faster than in DMSO solvent and the photo decay kinetic was found to follow first order reaction in ethanol and second order in DMSO solution.
