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تاثـير بـعـض الـعوامل الـبـيـئـية عـلى نمـو الاحياء الدقيقة في بعض القاعات الانتاجية لمصنع ادوية سامراء == The Effect of Some Ecological Factors On The Growth of Microorganisms In Some Production Units In Sammara Drug Industry (SDI)
Author name:
خالد محمد عباس
Supervisor name:
حميد سلمان خميس المهداوي
General topic:
Biology
Specific topic:
Life Science
Degree:
Master
University:
Tikrit University - Faculty Of Education - Department Of Biology
Language:
Arabic
University location:
Salahaddin
First pages:
24T3015 - p.pdf
Abstract:
تم دراسة الظروف الطبيعية الموجودة في القاعات الانتاجية لمصنع ادوية سامراء من خلال العوامل البيئية التي شملت الحرارة، والرطوبة النسبية. وشدة الاضاءة واعداد حجم الدقائق العالقة في الهواء وتاثيرها على الاحياء المجهرية الموجودة في القاعات الانتاجية حيث تم اخذ | The natural environmental conditions existing in the production units of Sammara drug company have been studied. Environmental factors included, temperature, relative humidity, light intensity as well as number and size of suspended particles in the air. From December 2006 through June 2007. 87 sampling visit was made during which 384 swabs were collected from three production buildings : Ibn - Hayan, Ibn - Sina and Al - Zahrawy. Results showed that at different temperature levels during this study dominance of bacterial colony over fungal colony in two buildings Ibn - Hayan and Ibn - Sina, was observed, whereas the dominance of fungal colony over bacterial colony in Al - Zahrawy building was noticed. While the effect of relative humidity on microorganisms showed that in Ibn - Hayan building at low relative humidity (41 - 53%) the dominance of bacterial colony over fungal colony whereas the dominance of fungal colony on bacterial colony at relative humidity (53 - 62%). While in Ibn - Sina building bacterial colony dominante fungal colony except at high relative humidity (63 - 73%), where the fungal colony dominance. The same pattern have shown in Al - Zahrawy building at low relative humidity less than 51% while fungal colony exceeded bacterial colony at high relative Humidity. Result of the effect of light intensity showed that the low light intensity have greater effect on fungal colony than bacterial colony this clear in Ibn - Hayan and Ibn - Sina buildings whereas increases in light intensity showed the reverse while the low light intensity in Al - Zahrawy building shown different effects which the dominance of fungal colony over bacterial colony. This perhaps reflects the different species of fungal colony in production units.The effect of the number and the size of 0.3 micron of particulates on bacterial and fungal colony was also examined. It has been noticed that the dominance of bacterial colony over fungal colony until the number of particulates 49000/foot3 in Ibn - Hayan building, while fungal colony appeared in most swabs in Ibn - sina building, but dominancy for bacterial colony. While in Al - Zahrawy building the swabs showed clear appearance for fungal colony, but some swabs shown high bacterial growth. The effect of 0.5 micron particulates showed that the dominance of bacterial colony with increased number of particulates in Ibn - Hayan building. The same pattern was shown in Ibn - Sina building, while in Al - Zahrawy building it has been the dominances of bacterial colony until 15000/foot3, but with increase in number fungal colony appear very clear. The following bacteria and fungi were identified during the course of this study; Staphylococcus, E.coli and a low genera of fungi like Penicillium, Aspergillus, Mucor. It has been shown by the collected swabs that the contamination with bacteria and fungi of drug production units never exceeded the standard limits set by the company except in very rare occasions the high contamination rate occurred in the hands of workers and delivery boxes in Ibn - Sina building.
