Share
دراسة مقارنة للجرعة الاشعاعية القلبية بانواع مختلفة من العمليات الجراحية لمرضى سرطان الثدي في مركز بغداد للعلاج الشعاعي == Comparative study of cardiac radiation dose with different types of surgery in breast cancer patients in Baghdad radiotherapy center
Author name:
سجاد عباس خير الله
Supervisor name:
خضير جاسم صبيح الرواق
General topic:
Medicine
Specific topic:
Therapeutic Radiology
Degree:
Higher Diploma
University:
University of Baghdad - Faculty Of Medicine
Language:
English
University location:
Baghdad
First pages:
19T1607 - p.pdf
Abstract:
Radiotherapy has been shown to decreases breast cancer recurrence as well as reduce in breast cancer mortality. The dose of radiation is important to be calculated accurately for both the site to be treated and for the organs to be protected such as the heart as it has major impact on morbidity and mortality on patients if received high dose of radiotherapy.Aim of study : To compare the mean heart dose of radiation in breast cancer patients between breast conserving surgery VS mastectomy, between different radiotherapy doses and fractionation schedules and between right and left breast cancer irradiation.Patients & Methods : This is a cross - sectional descriptive retrospective comparative study that was conducted in Baghdad Radiotherapy Center from January 2018 to June 2018 , carried on 174 breast cancer patients of different age groups selected randomly and their mean heart dose data collected from their files and database in Baghdad Radiotherapy Center. Patients are divided into two groups : Breast conserving surgery and modified radical mastectomy .each group is further subdivided according to dose of radiotherapy and side of breast cancer.VResults : The overall average of the mean dose was 372 cGy (range from 76.4 to 716.2).The greatest difference in the mean heart dose was between (BCS) patients who received 5000 cGy with regional nodal irradiation and (BCS) patients who received 4005 cGy also with regional nodal irradiation ( difference in the mean is 639.8 , the P - value <0.001 ) .In regard to the side of breast cancer , the greatest difference in mean heart dose seen between left and right breast cancer patients who did the same type of surgery (MRM) and received the same dose of radiotherapy (4256 cGy) (difference in the mean is 565cGy and the P - value <0.001 ) .No statistically significant difference in the mean dose between breast conserving surgery and mastectomy was recorded.Conclusion : The mean heart dose of radiotherapy is significantly increased in left sided breast cancer irradiation as compared to the right side. A dose of 5000 cGy has the greatest effect on the dose received by the heart especially in left breast cancer. The type of surgery whether breast conserving surgery or mastectomy did not affect the mean dose received by the heart
