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حدوث مرض الاسهال الحاد بين الاطفال دون سن الخامسة للاطفال في بغداد قبل وبعد التطعيم بلقاح الفيروس العجلي حزيران 2013 == Occurrence of Acute Diarrheal Disease among under Five Years Children in Baghdad before and after Rota Virus Vaccination, June 2013
Author name:
سنان اكرم عقراوي
Supervisor name:
بتول علي غالب ياسين
General topic:
Medicine
Specific topic:
Applied Epidemiology
Degree:
Higher Diploma
University:
University of Baghdad - Faculty Of Medicine
Language:
English
University location:
Baghdad
First pages:
19T1370 - p.pdf
Abstract:
Background : Approximately 39% of the global diarrhea deaths in children aged 5 years may be attributable to rotavirus infection. Two rotavirus vaccines were recently introduced to the market, with evidence of efficacy in the USA, Europe and Latin America. We sought to estimate the effectiveness of these vaccines against rotavirus morbidity and mortality.Objectives : To determine the association between infant rotavirus vaccination in Baghdad and the occurrence of acute diarrheal diseases, the rate of hospital admission for gastroenteritis and mortality among under five years children Methods : An observational, cross - sectional study of two time periods : 1 January - 31 August 2011 (prior to initiating rotavirus vaccination) and 1 January - 31 August 2013 (one year after introducing rotavirus vaccination). All cases of acute diarrhea among infants and under five years children during 2011 and 2013 were retrieved from surveillance section /CDC Baghdad, from Health and Vital statistics Department - MOH - Iraq and Pediatrics Hospital’s Statistical Units and analyzed. Discrete variables were presented as numbers and percentages. Z test for difference between two proportions was calculated with a 95% confidence interval (95% CI) Findings with P value less than 0.05 were considered significant.Results : The current study revealed a 32.7% decrease of acute diarrhea among under five years children (Z value= 7.967, p <0.0001, C.I. =0.0087 - 0.0143) and a decrease by 33.2% acute diarrhea infants (Z value= 41.4458, p > 0.0001, C.I. =0.0362 - 0.0398). The disease burden decreased by 51.9% for under five years and 28.2% for infants reductions in hospitalizations due to acute diarrhea and the case fatality rate decreased by 23% for under five years.Conclusions : A noticeable reduction in the occurrence of acute diarrhea among infants and under five years children, in hospital utilization and to less extent in the mortalities due to acute diarrhea after implementing the Rota virus vaccination for infants in Iraq.
