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تقييم التشخيص الكهروفسلجي الناتج عن خلل الوظيفة اللا ارادية في مرضى داء السكري == ELECTRODIAGNOSTIC EVALUATION OF AUTONOMIC DYSFUNCTION IN DIABETES MELL
Author name:
نهال مهند لطفي
Supervisor name:
عبد الناصر حسين امير
General topic:
Medicine
Specific topic:
Physiology
Degree:
Master
University:
University of Baghdad - Faculty Of Medicine
Language:
English
University location:
Baghdad
First pages:
19T1647 - p.pdf
Abstract:
Diabetic autonomic neuropathy is a serious and common complication of diabetes. The most studied and clinically important form of diabetic autonomic neuropathy is cardiovascular autonomic neuropathy.Aim of study : To assess the autonomic dysfunction in diabetics electrodiagnoctically using reliable tests by sympathetic skin response and R - R interval tests.A cross - sectional study was conducted in the Electromyography unit in Baghdad Teaching Hospital between (Feb/1/2018 - May/15/2018). It included all adult male and female with symptoms of neuropathy or autonomic dysfunction. Pregnant women were excluded from the study. Neurological tests were performed as sympathetic skin response, and R - R interval including normal and deep breath, Valsalva and tilt tests).Means of sympathetic skin response amplitude, R - R interval (Valsalva), and R - R interval (tilt) tests were significantly higher in non - diabetic patients than diabetics (2.19 versus 0.541, P= 0.001; 1.75 versus 1.48, P= 0.017; and 1.44 versus 1.01, P= 0.002 respectively). They were also significantly higher in controlled than in uncontrolled diabetic patients (1.69 versus 0.15, P= 0.044; 1.99 versus 1.31, P= 0.039; and 1.23 versus 0.941, P= 0.022 respectively). Cut points of these tests between controlled and uncontrolled diabetic patients were (0.81, 1.84, and 1.04 respectively). This mean that all patients with tests below these values can be considered uncontrolled diabetics.Sympathetic skin response amplitude, and R - R interval tests are good electro diagnostic tests to evaluate the autonomic dysfunction affected by diabetes, and to assess the severity of autonomic dysfunction in uncontrolled diabetes and differentiating them from those with controlled diabetes.
