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تحضير وتشخيص بعض مشتقات4,2,1 و4,3,1 - اوكسادايازول وتقييم فعاليتها البايولوجية == Synthesis And Characterization of Some (1,2 ,4 & 1,3 ,4) - Oxadiazoles And Evaluation Their Biological Activity
Author name:
بشرى فيصل نعمان
Supervisor name:
خالد مطني محمد الجنابي
General topic:
Chemistry
Specific topic:
Inorganic Chemistry
Degree:
Master
University:
Tikrit University - College Of Science For Girls - Chemistry Department
Language:
Arabic
University location:
Salahaddin
First pages:
25T1499 - p.pdf
Abstract:
في هذه الدراسة تم تحضير ثلاثة ليكاندات ازو اميدازول جديدة (L1 - L3) وتم تشخيصها بوساطة اطياف ,C.H.N ,1HNMR, 13CNMR, UV - Vis, I.R طيف الكتله اضافه الى الطرائق الفيزيائيه من ذوبانيه ودرجة انصهار.حضرت عدد من المعقدات الجديدة لايونات Cd(II), Zn(II), Ni(II) | In this work, three azo imidazole ligands [L1 (2,3 - DMBAI), L2 (2 - CyBAI) and L3 (4 - SuBAI) ] have been prepared and characterized by I.R, UV - Vis spectra, (C.H.N.) microanalysis, 1HNMR, 13CNMR, mass spectroscopy and other physical properties like solubility and melting point measurements.A wide range of new complexes of Co( ), Ni( ), Cu( ), Zn( ), Cd ( ) and Hg ( ) with azo ligands (L1 - L3) were prepared after fixing the optimum conditions of pH and molar concentration. The structures of these complexes were assigned according to the molar ratio, which was obtained from the spectroscopic studies of the complexes solution of the above metal ions. However, metal - ligand (M : L) ratio of 1 : 2 were obtained.Stability constant have been founded in optimum concentration and optimum pH of complexes.The percentages of the metals in the complexes have been measured by flame atomic absorption spectrophotometer (A.A.) technique. Conductivity measurements with optimum concentration of prepared complexes have shown non - ionic character for all complexes in ethanol.The magnetic susceptibility measurements of Zn ( ), Cd ( ) and Hg ( ) complexes exhibit diamagnetic behavior, while paramagnetic properties were recorded for all the other complexes The UV - Vis spectra of the prepared complexes showed bathachromic shift in ?max , while the IR spectra ( using KBr disc) of the complexes showed changes in the band shape and density formed with those of the free ligand which indicated the complexation between the metal ions and ligands through the N atom of imidazole and azo group The analysis results showed that the proposed geometrical structure were octahedral configuration for all complexes and the general formula are : [M (Ln)2 X2 ]. mH2O , when M= Co( ), Ni( ), Cu( ), Zn( ),Cd ( ) and Hg ( ) ; L= ligands ; n= 1 - 3; X= Cl ; m= 0,1,2.
