تقييم جهاز كتلة غاز الزفير كوسيلة لفحص وظائف الرئتين عند العراقيين الاصحاء == Evaluation of Expiratory Gas Mass Device As A Measure of Lung Function Test In Healthy Iraqi Subjects
Author name:
نبراس حسين عبد الساده الحسناوي
Supervisor name:
يسار محمد حسن الشماع | باسم متعب هادي زوين
General topic:
Medicine
Specific topic:
Physiology
Degree:
Master
University:
University of Kufa - Faculty Of Medicine - Department Of Physiology And Medical Physics
Language:
English
University location:
Najaf
First pages:
19T1122 - p.pdf
Abstract:
تعد فحوصات وظائف الرئتين من الوسائل المفيدة جدا لاغراض التشخيص والمتابعة والبحث العلمي للاصحاء ومرضى الجهاز التنفسي. وابسط تلك الفحوصات واكثرها معلومة هو الفحص السبايرومتري الذي يتضمن قياس السعة الحيوية القسرية (FVC) , وحجم الزفير القسري في الثانية الا | Lung function tests are very useful diagnostic, follow up and research measures for healthy and respiratory compromised subjects. The simplest, yet the most informative, lung function tests are the spirometric tests.They involve the forced vital capacity (FVC), the forced expiratory volume in first second (FEV1) and the forced expiratory volume ratio (FEV%). Several types of devices are used to perform spirometric tests based on the measurement of lung volumes and their subdivisions. Lung volumes, hence, are represented by the volume of expired air. There was a controversy about the difference between body and ambient temperatures which may extremely affect gas volume , but this is thought to be solved by temperature correction. Temperature correction, however, may not be the precise solution in extremely fluctuating environmental temperatures. A fixed amount of expired gas has a constant mass despite the changes in pressure or volume as is implied by the law of conservation of mass in a closed system by Antoine Lavoisier. The aim of this study is to construct and evaluate a simple device called expiratory gas mass device as a reliable, reproducible, accurate and convenient tool to substitute Vitalograph spirometer as a measure of lung function in healthy Iraqi subjects and testing the hypothesis that expired gas mass could significantly and acceptably alternate or conjugate its volume as measures of lung function. The design of the study is a cross sectional study. The statistically required number of participants was decided by a professional statistician to be 70 healthy subjects. However, 300 healthy subjects are included in the present research to cover the need for subgrouping (146 male and 154 female) aged 20 - 50 years (31.84 ± 9.28 years). The male and female were classified into three age groups for each one, ten years interval was considered to be suitable for classifying subjects.Subjects with abnormal lung function such as smokers were excluded. A uniform case sheet was assigned for every participant in the study which includes, name, gender, age, weight, height, smoking habits, residence, cultural status, socioeconomic status, present and past medical history, family history of respiratory illnesses. They were asked to perform the forced expiratory maneuver through the standardized spirometer and then through the newly constructed gas mass device.The accuracy (systematic error) and reproducibility (random error) were tested for the constructed gas mass device.A comparison between forced vital capacity (FVC) and adjusted gas mass (AGM) was made on two main groups , the male group and female group, both of them were subdivided to three age groups.The results revealed that there were no significant differences in values of FVC and AGM measured by standard Vitalograph spirometer and gas mass device respectively. Regression lines indicated that there were strong positive correlations between gas mass (GM) and FVC in male and female. Separate data for male and female are processed and the results indicated that FVC values and GM (or AGM) values are significantly higher in male than in female , P?0.05. Regression lines indicated that there was a negative correlation between age and both of FVC and GM, a positive correlation between height and both of FVC and GM and a weak positive correlation between weight and both of FVC and GM. From the present study, it can concluded that gas mass device is simple, portable and easily handled device. It is also reproducible and accurate device for the measurement of GM in normal subjects.
