اورام الدماغ الثانوية المنتشرة ضمن الاورام السرطانية الصلبة == Secondary brain metastasis in solid tumors
Author name:
افيل نديم كاظم
Supervisor name:
خضير جاسم صبيح الرواق
General topic:
Medicine
Specific topic:
Diagnostic Radiology
Degree:
Higher Diploma
University:
University of Baghdad - Faculty Of Medicine
Language:
English
University location:
Baghdad
First pages:
19T1347 - p.pdf
Abstract:
Title : Secondary brain metastasis in solid tumors.Background : Brain metastases are among the most feared complications of cancer because they often cause profound neurologic symptoms that severely impair the quality of life. They represent a common complication, occurring in 10 - 30% of cancer patients. The prevalence of brain metastases in cancer patients has been rising over the past three decades.Aims of the study : To investigate the distributions of secondary Brain metastases and their percentage of frequency among common solid tumors and to correlate the strength of the relationship with different prognostic criteria that are obtained from common primary diseases which ended up with secondary brain metastases in Al - Amal hospital for radiation oncology and nuclear medicine .Patients and methods : Clinical data of 40 patients with brain metastatic cancers were collected and analyzed for the relationship between survival time and age, gender, primary diseases, quantity of brain metastatic foci, their position, extra cranial lesions, and therapeutic regimens used before brain metastasis detection.Results : The average female to male ratio was 3.4 : 1, with highest frequency were among patients in the 4th and 5th decades, females with breast cancer showed the highest frequency to develop brain metastases. Highest frequency was seen at 1 - 5 years after diagnosis of the primary disease. Majority of patients were treated with surgery and chemotherapy showed a high frequency for brain metastases.Conclusion : Female gender 30 - 50 years age having breast cancer, between 1 - 5 years after the diagnosis of the primary disease are at high risk for secondary brain metastases.Keywords : Secondary brain tumor, brain metastases, cerebral cancer treatment, brain neoplasm, metastasis