التاثير الموضعي لعلاج الفيناسترايد في علاج مرض الشعرانية مجهولة السبب == The Effect of Topical Finasteride In Treatment of Idiopathic Hirsutism
Author name:
يحيى ابراهيم يحيى
Supervisor name:
نسرين جلال محمد البياتي | وسام علي امين
General topic:
Medicine
Specific topic:
Medicines and Toxins
Degree:
Master
University:
University of Babylon - Faculty Of Medicine - Department Of Medicine
Language:
English
University location:
Babylon
First pages:
19T1125 - p.pdf
Abstract:
يعرف مصطلح الشعرانية هو الشعر الاكثر خشونة وسمكا في النساء مثل نمط والمواقع في الذكور , الاندروجين المسؤولة عن تغير في الصوت وزيادة في كتلة العضلات في المراة هو هرمون التستوستيرون، وانه المسؤول عن الشعرانية، ونظرا لحدوث درجة عالية من هذا المرض في العراق | The term hirsutism defines as presence of coarser, thicker and terminal hair in women in a male like pattern and locations.The androgen responsible for the change in voice and the increase in muscle mass in women is testosterone, and that responsible for hirsutism and due to the highly incidence of this disease in Iraq so the finasteride cream 1% used and the study was carried out in Collage of Medicine / Babylon University from November 2013 - November 2014 for treatment of fifty five females were enrolled in this study. Their age was between (18 - 55 years) and the mean of their age was 32.26. Those females were chosen from Consulting dermatologist department in Mergan medical city in Babylon in which these females were complained from hirsutism and After preparation Finasteride 1% cream and using it by the patients it was measured TSH,FSH,LH and free Testosterone and the follow up every 15 day and after 3 months (end of study) it was measured the same parameters TSH,FSH,LH and free Testosterone and ferryman gallawy scores the patients had two parts : (Pretreatment) the patients with TSH,FSH,LH and free Testosterone level before treated with finasteride cream. (Post treatment) the patients were taking the Finasteride cream and the TSH,FSH,LH and free Testosterone levels measured after three months of treatment with finasteride cream and also measured the : • Hair color• Hair removal frequency of the patients• Pain severity before and after treatment• F - Gallawy score• Visual analogue scoreand the follow up every 15 day and after 3 months (end of study) it was measured the same parameters Finasteride cream 1% had significant decrease in the serum free testosterone levels with no significant effects on others parameters as TSH and FSH and LH level. From the above results we can conclude the following : Finasteride cream 1% is an effective and harmless treatment in patients whom suffer from idiopathic hirsutism.
