البروتين التفاعلي - C عالي الحساسية, الانترلوكين6 والفيبرينوجين كدليل على امراض القلب التاجية == Highly - Sensitivity C - Reactive Protein, Interleukin6 And Fibrinogen As Predictor of Coronary Heart Disease
Author name:
فرح حقي عزت
Supervisor name:
حميد محمود مجيد
General topic:
Biology
Specific topic:
Zoology
Degree:
Master
University:
University of Diyala - College Of Education For Pure Sciences - Department Of Biology
Language:
Arabic
University location:
Diyala
First pages:
24T2840 - p.pdf
Abstract:
يعد مرض القلب التاجي (CHD) Coronary heart disease من الامراض متعددة الاسباب والتي تثار حولها العديد من التساؤلات، الا ان ارتفاع مستويات بروتينات الطور الحاد مثل البروتين التفاعلي C عالي الحساسية hs - CRP والفيبرينوجين والحركيات الخلوية مثل انترلوكين6 - (I | Coronary heart disease (CHD) considered a multifactorial disease. raising many questions about the early marker of the disease. And these include high sensitivity C - reactive protein (hs - CRP) fibrinogen and cytokines such as interleukin - 6 (IL - 6) considered a predictors of coronary heart event. and to reveal their roles in cardiac events we constructed this study. we prepared a special from for each patient and it include : age, sex, hieght, weight, and measurement of systolic blood pressure, diastolic blood pressure, fasting blood sugar, total cholesterol, triglycerides, high density lipoprotein, low density lipoprotein, very low density lipoprotein, high sensitive C - reactive protein, fibrinogen, interleukin - 6. The study included two groups : The first group included 120 people suffering from coronary heart disease and admitted to the coronary care unit (CCU) in Baquba Teaching Hospital aged between 31 - 70 years for the period from the first of November 2014 and first of May until 2015. The second group of 66 healthy people aged between 31 - 70 years for the same period. The study results showed : The existence of high statistical difference with probability of P<0.01 in the body mass index, systolic blood pressure, fasting blood sugar, total cholesterol, triglycerides, low density lipoprotein, very low density lipoprotein, high sensitive C - reactive protein, fibrinogen, interleukin - 6. while showed significant decrease <0.01 in the level of High density lipoprotein and high level of P<0.05 in the diastolic blood pressure in coronary heart disease patients compared to the control group. wich predict an increased mortality in patients
