دراسة عدد من المتغيرات الفسلجية والمناعية لدى النساء المصابات بالتهاب السبيل البولي في مدينة تكريت == Study Some of Physiological And Immunological Parameters In Women With Urinary Tract Infections In Tikrit City
Author name:
لبنى عبد الجبار ياسين
Supervisor name:
موسى جاسم محمد الحميش
General topic:
Biology
Specific topic:
Zoology - Physiology
Degree:
Master
University:
Tikrit University - College Of Science - Department Of Biology
Language:
Arabic
University location:
Salahaddin
First pages:
24T2932 - p.pdf
Abstract:
ان الهدف الرئيس لهذه الدراسة هو معرفة علاقة الانترلوكينات(IL - 2, IL - 4, IL - 6) ببعض الهرمونات لدى النساء المصابات بالتهاب السبيل البولي.تضمنت هذه الدراسة 116عينة دم من النساء المراجعات للعيادات الخارجية التابعة لمستشفى تكريت التعليمي اللواتي تترواحت اع | The main objective of this study is to investigate the relationship of Interleukines (IL - 2, IL - 4, and IL - 6) with hormones in women with inflammation of the urinary tract. This study involved (116) women visiting outpatient clinic of Tikrit Teaching Hospital for the period from September 2011 until February 2012. The ages of women were 16 - 50 years, and blood samples were taken for each of these women for the purpose of determining the levels of sex hormones (FSH, LH, estrogen, progesterone, testosterone) and the levels Interleukines (IL - 6, IL - 4, IL - 2) and identify some of the variables blood parameters (WBC, ESR) and C - reactive protein Twenty samples were taken from the blood of women who are not infected and non - pregnant as a control group samples. The patients divided into three groups, which included non - pregnant women infected and pregnant women who are infected and pregnant non - infected urinary tract (UTI) also samples of the study was divided by periods of gestation into three periods included the first period (1 - 12 weeks) and the second period (12 - 24 weeks) and the third period (24 - 40 weeks) of pregnancy The results of the current study showed that there is significant increase in ESR for a pregnant women infected and pregnant women non - effected with UTI when compared to control (P ? 0.01) and highest level of ESR was in the last third of pregnancy, The total Count of white blood cells (WBC), results showed a significant difference between the three groups compared to the control group, had the highest level for (WBC) in the last third of pregnancy. As for the study of hormones when measuring the level of the hormone LH showed a significant decrease (P ? 0.05) for the three groups compared to control and the steepest decline of hormone level was in the last third of pregnancy. The hormone FSH got a significant decrease in the three groups compared with a control (P ? 0.01), lowest level was in the third trimester of pregnancy.Estrogen level showed a significant decrease (P ? 0.01) for a non pregnant women with UTI compared with a control, and show a significant increase in the level of the two sets of hormone - positive pregnant non - infected, and the highest increase was in last third of Pregnancy in both groups. The progesterone showed a significant increase in the level of the pregnant infected and pregnant non - infected (P ? 0.01) compared with a control group. While in non - pregnant, there is no significant difference. The testosterone level increased significantly (P ? 0.05) in the three groups compared to control group. the level Interleukines, Tests showed that a significant increase(p ? 0.01) in the level of interleukin - 2 (IL - 2) for a pregnant women with (UTI) compared with a control and a significant decrease in the last third of pregnancy in pregnant women which is non infected compared to the rest of the gestation periods, and for the level of interleukin - 4 The present study showed a significant increase (p ? 0.01) in the level of interleukin - 4 (IL - 4) for a non - pregnant women with (UTI) compared with a controlThe highest level reached by IL - 4 was in the last third of pregnancy in the non - infected at (p ? 0.05), interleukin - 6 has a significant decrease for the two sets of pregnant women with (UTI) and non - infected, compared with the control group and the absence of significant differences between the two sets of pregnant women infected and non - infectedRegarding level of C - reactive protein there is a significant increase (P ? 0.01) in the two groups of pregnant and non pregnant women compared with a control, and significant differences between control group and a group of pregnant non - infected.
