المستودع الرقمي العراقي
Iraqi Digital Repository
تخليق قواعد شف جديدة مشتقة من انهدريد البايرومليتك == Synthesis ,Antibacterial of Some Novel Schiff Bases Derived From Pyromellitic Dianhydride
اسم المؤلف:
عذراء محمد سلوم
اسم المشرف:
امينة عبد الرحمن فياض | عماد تقي علي
الموضوع العام:
علوم الكيمياء
السنة:
2014
الموضوع الدقيق:
الكيمياء
الدرجة:
ماجستير
الجامعة:
جامعة بغداد
اللغة:
الانكليزية
مكان الجامعة:
بغداد
الصفحات الاولى:
📎 25T1508 - p.pdf
المستخلص:
تم تخليق قواعد جديده مشتقة من انهدريد ثنائي البايرومليتك بعدة خطوات. حيث حضرت مشتقات حامض البايرومليتك المتناظره ac[ I ] من تفاعل انهدريد ثنائي البايرومليتك مع بعض الامينا ت الاورماتية الحاويه على (مجاميع ساحبه واخرى دافعة ) في الاسيتون كمذيب. واشتملت | The novel Schiff bases derived from pyromellitic dianhydride were synthesized by several steps reaction. A symmetrical diamic acide [I ]a - c was synthesized by the reaction of pyromellitic dianhydride with some aromatic amines (containing electron withdrawing , repulling groups ) in dry acetone.In the second step the diacids were converted to their corresponding diimide [II ]a - c using acetic anhydride and sodium acetate system as a dehydrating agent, via the intramolecular cyclization steps of amic acids.The third step was to synthesis the hydrazone derivatives from the reaction of diimides , with 80 % hydrazine hydrate at (50 - 60)C?.These hydrazone derivatives were allowed to react with several aromatic aldehydes to form new Schiff bases via step four at a temperature near by (80 - 85)C?. As shown in the following scheme (3.1). All the novel compounds and their structures have been ascertained by their melting points , mixed melting points , C.H. N analysis , FTIR , UV - Viss. and 1HNMR spectroscopy for some of them. Also the biological activity of some of them was studied which showed that these compounds have different activities towards the studied bacteria.
مشاركة البيانات
Share Data