تخليق وتشخيص لبعض المركبات الحلقيه الغير متجانسه كالبيتا لاكتام والكاما لاكتام وفق تفاعل كانيكوزا == SYNTHESIS AND CHARACTRIZAITION OF SOME NEW HETROCYCLIC COMPOUNDS INCLUDING ? & ? LACTAMS BY USING KINUGASA REACTION
Author name:
دعاء هادي محسن العطار
Supervisor name:
محمود شاكر مكطوف | محسن عريبي الدخيلي
General topic:
Chemistry
Specific topic:
Organic Chemistry
Degree:
Master
University:
University of Thi-Qar - College Of Science - Chemistry Department
Language:
English
University location:
Dhi Qar
First pages:
25T1900 - p.pdf
Abstract:
This study is concerned with the synthesis and characterization of the some β- lactams 3(a-f),as in (Table.2). These compounds 3(a-f) were prepared by reacting phenylactylene with the appropriate nitrones2(a-f), in the presence of triethylamine | in acetronitrel under nitrogen atmosphere at -10˚C. in moderate yield (50-70)% . The nitrones compound 2(a-f) were prepared by reacting aldehyde with appropriate N-phenyl hydroxyl amine 1 in the presence of Ethanol. | As in (Table.1) Also the N-phenyl hydroxyl amine 1 compounds were prepared by reduction of nitrobenzene with ammonium chloride in Zinc Powder in the presence of water.This study is concerned with the synthesis and characterization of mono-γ- | lactams and bis-γ-lactams These compounds were prepared by reaction phenylsuccinic anhydride with the appropriate schiff bases(imines), by using chloroform solvent and heated at temperature (51-61˚C) in moderate yields(70- 92)%, All this compound confirmed by using spectra data such as : , IR , 1H-NMR , 13CNMR , APT 13C-NMR , HSQC 1H-13C-NMR,Mass
